MCID: RTN003
MIFTS: 56

Retinal Ischemia malady

Summaries for Retinal Ischemia

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63Wikipedia, 32MalaCards
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Wikipedia:63 Ocular ischemic syndrome is the constellation of ocular signs and symptoms secondary to severe, chronic... more...

MalaCards: Retinal Ischemia, also known as retinal ischaemia, is related to ischemia and glaucoma. An important gene associated with Retinal Ischemia is SETD2 (SET domain containing 2), and among its related pathways are Signaling events mediated by VEGFR1 and VEGFR2 and TNF Signaling. The compounds butyrate and resveratrol have been mentioned in the context of this disorder. Affiliated tissues include eye, endothelial and bone, and related mouse phenotypes are renal/urinary system and endocrine/exocrine gland.

Aliases & Classifications for Retinal Ischemia

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8Disease Ontology, 44Novoseek, 30LifeMap Discovery™, 60UMLS, 56SNOMED-CT, 27ICD9CM
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Aliases & Descriptions:

retinal ischemia 8 44 30 60
retinal ischaemia 8


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Disease Ontology8 DOID:12510
SNOMED-CT56 26468004, 193427006
ICD9CM27 362.84

Related Diseases for Retinal Ischemia

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17GeneCards, 18GeneDecks
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Diseases related to Retinal Ischemia via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 208)
idRelated DiseaseScoreTop Affiliating Genes
1ischemia31.6ADORA1, SETD2, NOS2, GFAP, CXCL12, HIF1A
2glaucoma30.4ADORA1, HSPB1
3retinal disease30.4SETD2, GFAP, HIF1A, VEGFA, KNG1
4diabetic retinopathy30.4NOS2, CXCL12, HIF1A, VEGFA, SOD1
5hypertension30.2KNG1
6macular retinal edema30.1CXCL12, VEGFA
7cataract30.1SOD1, CAT, HSPB1, TXN
8adult t-cell leukemia29.9TXN
9proliferative diabetic retinopathy29.9GFAP, CXCL12, HIF1A, IGFBP2, VEGFA
10retinal vascular disease29.9VEGFA, TXN
11hyperglycemia29.9NOS2, HIF1A, SOD1, CAT, TXN
12vascular disease29.9SETD2, NOS2, VEGFA, KNG1, SOD1, CAT
13multiple sclerosis29.9ADORA1, BCL2L1, NOS2, GFAP, CXCL12, IGFBP2
14leukemia29.9BCL2L1, SETD2, CXCL12, BAK1, BAX, IGFBP2
15melanoma29.9BCL2L1, SETD2, PCNA, HIF1A, BAK1, BAX
16retinitis11.2
17neuronitis10.5
18retinal artery occlusion10.3
19retinal degeneration10.3
20choroiditis10.2
21carotid artery occlusion10.2
22retinal vein occlusion10.2
23neurofibromatosis10.1
24neovascular glaucoma10.1
25cerebritis10.1
26temporal arteritis10.1
27carotid artery disease10.0
28cystic fibrosis10.0ADORA1
29endometriosis10.0VEGFA
30sarcoma10.0HSPB1
31dilated cardiomyopathy10.0TXN
32psoriasis10.0BAK1
33brain ischemia10.0ADORA1
34nephrotic syndrome10.0IGFBP2
35gastric ulcer10.0HSPB1
36age related macular degeneration10.0VEGFA
37hepatitis c10.0CXCL12
38huntington's disease10.0CHAT
39hemangioma10.0VEGFA
40severe combined immunodeficiency10.0CXCL12
41schizophrenia10.0CHAT
42esophagitis10.0CAT
43vasculitis10.0NFKB1
44malaria10.0KNG1
45sjogren's syndrome10.0BAX
46glucose intolerance10.0TXN
47anorexia nervosa10.0IGFBP2
48polycystic ovary syndrome10.0IGFBP2
49angiosarcoma10.0CHAT
50rhinitis10.0KNG1

Graphical network of the top 20 diseases related to Retinal Ischemia:



Diseases related to retinal ischemia

Clinical Features for Retinal Ischemia

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Drugs & Therapeutics for Retinal Ischemia

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 30LifeMap Discovery™, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Retinal Ischemia

Drug clinical trials:

Search ClinicalTrials for Retinal Ischemia

Search NIH Clinical Center for Retinal Ischemia

Search CenterWatch for Retinal Ischemia

Cell-based therapeutics:


LifeMap Discovery
The database of embryonic development, stem cell research and regenerative medicine
Read about Retinal Ischemia cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Retinal Ischemia:
Bone marrow-derived stem cells for retinal diseases
Embryonic/Adult Cultured Cells Related to Retinal Ischemia:
Bone marrow-derived mononuclear cells (family), PMIDs: 23049424, 21225138, 19347139, 23000646

Genetic Tests for Retinal Ischemia

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Anatomical Context for Retinal Ischemia

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32MalaCards
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MalaCards organs/tissues related to Retinal Ischemia:

32
Eye, Endothelial, Bone, Retina, Spleen, Brain, T cells, B cells

Animal Models for Retinal Ischemia or affiliated genes

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36MGI
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Publications for Retinal Ischemia

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50PubMed
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Articles related to Retinal Ischemia:

(show top 50)    (show all 256)
idTitleAuthorsYear
1
Protective effect of pioglitazone on retinal ischemia/reperfusion injury in rats. (23557740)
2013
2
Baicalein protects against retinal ischemia by antioxidation, antiapoptosis, downregulation of HIF-1I+, VEGF, and MMP-9 and upregulation of HO-1. (23537149)
2013
3
Synergistic protective effects of escin and lowa89dose glucocorticoids on blooda89retinal barrier breakdown in a rat model of retinal ischemia. (23525122)
2013
4
Modeling of diseases of retinal ischemia in vitro: possible participation of autocrine vascular endothelial growth factor signaling. (23257772)
2013
5
Progressive morphological changes and impaired retinal function associated with temporal regulation of gene expression after retinal ischemia/reperfusion injury in mice. (23800383)
2013
6
Toll-like receptor 4 mediates retinal ischemia/reperfusion injury through nuclear factor-I_B and spleen tyrosine kinase activation. (23908181)
2013
7
p38 mitogen-activated protein kinase-induced nuclear factor kappa-light-chain-enhancer of activated B cell activity is required for neuroprotection in retinal ischemia/reperfusion injury. (22876136)
2012
8
Endovascular coiling of the ophthalmic artery in pigs to induce retinal ischemia. (21622700)
2011
9
Pharmacological preconditioning by low dose cobalt protoporphyrin induces heme oxygenase-1 overexpression and alleviates retinal ischemia-reperfusion injury in rats. (21275512)
2011
10
Vitreal oxygenation in retinal ischemia reperfusion. (21051734)
2011
11
Necroptosis, a novel form of caspase-independent cell death, contributes to neuronal damage in a retinal ischemia-reperfusion injury model. (20025059)
2010
12
Time-dependent effects of focal retinal ischemia on axonal cytoskeleton proteins. (20089877)
2010
13
Protective effects of caffeic acid phenethyl ester on retinal ischemia/reperfusion injury in rats. (20858115)
2010
14
Effect of lutein on retinal neurons and oxidative stress in a model of acute retinal ischemia/reperfusion. (18936152)
2009
15
The porcine retinal vasculature accessed using an endovascular approach: a new experimental model for retinal ischemia. (19516013)
2009
16
Edaravone (MCI-186), a free radical scavenger, attenuates retinal ischemia/reperfusion injury in rats. (18565280)
2008
17
The effect of thalidomide on vascular endothelial growth factor and tumor necrosis factor-alpha levels in retinal ischemia/reperfusion injury. (17786465)
2008
18
Epigallocatechin-3-gallate reduces retinal ischemia/reperfusion injury by attenuating neuronal nitric oxide synthase expression and activity. (18289530)
2008
19
The neuropeptide NAP provides neuroprotection against retinal ganglion cell damage after retinal ischemia and optic nerve crush. (18414890)
2008
20
Localized retinal ischemia as an ocular manifestation of primary antiphospholipid syndrome. (17508052)
2007
21
Bevacizumab and retinal ischemia. (17980746)
2007
22
The role of clusterin in in vitro ischemia of human retinal endothelial cells. (17852194)
2007
23
TNF-alpha is critical for ischemia-induced leukostasis, but not retinal neovascularization nor VEGF-induced leakage. (17107717)
2007
24
Effect of thalidomide on endostatin levels in retinal ischemia/reperfusion injury. (17947830)
2007
25
Differential sensitivity of in vivo and ex vivo diffusion tensor imaging to evolving optic nerve injury in mice with retinal ischemia. (16797189)
2006
26
Retinal ischemia: mechanisms of damage and potential therapeutic strategies. (14766318)
2004
27
Early activation of caspase-1 after retinal ischemia and reperfusion injury in mice. (15161540)
2004
28
Mitogen-activated protein kinases and retinal ischemia. (14638742)
2003
29
Interleukin-6 in retinal ischemia reperfusion injury in rats. (12939322)
2003
30
Protective effects of pentoxifylline in retinal ischemia/reperfusion injury. (12913323)
2003
31
The monocarboxylate transport inhibitor, alpha-cyano-4-hydroxycinnamate, has no effect on retinal ischemia. (14519520)
2003
32
Effect of MCI-9042, a 5-HT2 receptor antagonist, on retinal ganglion cell death and retinal ischemia. (12634109)
2003
33
Retinal ganglion cell death after acute retinal ischemia is an ongoing process whose severity and duration depends on the duration of the insult. (11784707)
2002
34
Loss of retinal ganglion cells following retinal ischemia: the role of inducible nitric oxide synthase. (12457864)
2002
35
Expression of matrix metalloproteinases and their inhibitors in experimental retinal ischemia-reperfusion injury in rats. (12076079)
2002
36
Occurrence of hemispheric and retinal ischemia in atrial fibrillation compared with carotid stenosis. (12154246)
2002
37
Pigment epithelium-derived factor suppresses ischemia-induced retinal neovascularization and VEGF-induced migration and growth. (11867604)
2002
38
A possible role for p16INK4 in neuronal cell death after retinal ischemia-reperfusion injury. (9950615)
1999
39
Changes of GABA metabolic enzymes in acute retinal ischemia. (10375453)
1999
40
Role of nitric oxide during the initial phase of reperfusion after retinal ischemia in the rat. (9831818)
1999
41
The b-wave of the electroretinogram as an index of retinal ischemia. (9510075)
1998
42
Expression of vascular endothelial growth factor and its receptor, KDR, following retinal ischemia-reperfusion injury in the rat. (9846628)
1998
43
Postoperative retinal ischemia with self-sealing cataract surgery incisions. (9186109)
1997
44
Retinal ischemia induced by the intraluminal suture method in rats. (9292888)
1997
45
Involvement of adenosine in retinal ischemia. Studies on the rat. (8977474)
1996
46
Intraretinal study of cat electroretinogram during retinal ischemia-reperfusion with extracellular K+ concentration microelectrodes. (8113017)
1994
47
A paired comparison of two models of experimental retinal ischemia. (7956312)
1994
48
Influence of oxygenator type on the prevalence and extent of microembolic retinal ischemia during cardiopulmonary bypass. Assessment by digital image analysis. (2294366)
1990
49
Retinal ischemia during anesthesia. (13889836)
1961
50
Retinal ischemia with cataract formation; a case report. (13661282)
1959

Genetic Variations for Retinal Ischemia

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Expression for genes affiliated with Retinal Ischemia

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Retinal Ischemia

Search GEO for disease gene expression data for Retinal Ischemia.

Pathways for genes affiliated with Retinal Ischemia

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Sources:
37NCBI BioSystems Database, 55SinoBiological, 53Reactome, 12EMD Millipore, 51QIAGEN, 29KEGG, 49PharmGKB, 52R&D Systems, 4Cell Signaling Technology
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Pathways related to Retinal Ischemia according to GeneCards/GeneDecks:

(show all 47)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
9.9HSPB1, VEGFA, HIF1A
2
Hide members
9.9CASP2, BAK1
39.9SOD1, CAT
4
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9.9BAK1, BAX
5
Apoptosis and survival Caspase cascade
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9.9HSPB1, CASP2, BAX
6
Transcription P53 signaling pathway
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9.9HSPB1, VEGFA, NFKB1
7
Hide members
9.8CASP2, NFKB1, BAX
8
Hide members
9.8SOD1, KNG1, VEGFA
9
Apoptosis and survival Lymphotoxin-beta receptor signaling
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9.8NFKB1, BAX, CXCL12
109.7HIF1A, NFKB1, VEGFA, CHAT
119.7CAT, SOD1, NFKB1
12
Apoptosis and survival Anti-apoptotic action of nuclear ESR1 and ESR2
Hide members
9.7TXN, NFKB1, BAX
139.7NOS2, SOD1, CAT
149.6NOS2, CXCL12, HIF1A, VEGFA
159.6VEGFA, NFKB1, HIF1A, NOS2
169.6BCL2L1, NFKB1, HSPB1
179.6BCL2L1, CXCL12, NFKB1
18
Hide members
9.6HSPB1, VEGFA, NFKB1, NOS2
199.6TXN, CAT, SOD1
209.6NFKB1, NOS2, BCL2L1
219.5SOD1, NFKB1, HIF1A, NOS2
229.5BCL2L1, BAK1, BAX
23
Hide members
9.5BCL2L1, BAK1, BAX
249.5VEGFA, NFKB1, BAX, BAK1
25
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9.5CASP2, NFKB1, BAX, BAK1
26
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9.4BCL2L1, BAX, NFKB1, CASP2
27
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9.4CAT, SOD1, NFKB1, NOS2
28
Hide members
9.4CAT, NFKB1, BAX, BAK1
299.4PCNA, BAX, NFKB1, VEGFA
309.4BCL2L1, PCNA, NFKB1
319.3NFKB1, SOD1, CAT, TXN
32
Development Prolactin receptor signaling
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9.3BCL2L1, NOS2, BAX, NFKB1
33
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9.3TXN, CASP2, NFKB1, BCL2L1
34
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9.3BCL2L1, BAX, SOD1, CAT
35
Hide members
9.3NFKB1, BAX, PCNA, NOS2
36
Hide members
9.3VEGFA, NFKB1, BAX, HIF1A, BCL2L1
37
Hide members
9.2CASP2, NFKB1, BAX, CXCL12, BCL2L1
38
Hide members
9.1CASP2, BAX, BAK1, HIF1A, BCL2L1
39
Apoptosis and survival Apoptotic TNF-family pathways
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9.1BCL2L1, BAK1, BAX, CASP2, HSPB1
40
Hide members
9.0BCL2L1, BAK1, BAX, NFKB1, CASP2
419.0VEGFA, NFKB1, BAX, HIF1A, NOS2, BCL2L1
42
Hide members
9.0HSPB1, NFKB1, BAX, BAK1, PCNA
438.9TXN, CASP2, BAX, BAK1, BCL2L1
44
Hide members
8.8CASP2, NFKB1, BAX, BAK1, CXCL12, BCL2L1
45
Hide members
8.8NFKB1, IGFBP2, BAX, PCNA, BCL2L1
46
Hide members
8.8CASP2, KNG1, VEGFA, NFKB1, HIF1A, CXCL12
47
Hide members
8.5NFKB1, BAX, BAK1, HIF1A, CXCL12, GFAP

Compounds for genes affiliated with Retinal Ischemia

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Sources:
44Novoseek, 59Tocris Bioscience, 11DrugBank, 24HMDB, 28IUPHAR, 49PharmGKB, 2BitterDB
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Compounds related to Retinal Ischemia according to GeneCards/GeneDecks:

(show top 50)    (show all 241)
idCompoundScoreTop Affiliating Genes
1butyrate4410.6GFAP
2resveratrol44 59 11 2413.6TXN
3diphenyleneiodonium4410.5SOD1
4estrogen4410.2GFAP, CHAT, ADORA1
5rotenone4410.2BCL2L1, CASP2
6cycloheximide4410.1CXCL12, IGFBP2, CAT
7gsno449.6SETD2, TXN, CAT, SOD1, HIF1A
8superoxide44 2410.5SETD2, GFAP, BAK1, CASP2, TXN
9bapta449.5SETD2, HIF1A, KNG1, CASP2, ADORA1
10nitroglycerin44 1110.4HIF1A, NOS2, KNG1, SOD1, SETD2
11manganese superoxide449.4HIF1A, TXN, HSPB1, CAT, BCL2L1
12apocynin44 5910.3SETD2, NOS2, CAT, VEGFA, SOD1
13flavopiridol44 1110.2BCL2L1, HIF1A, BAK1, BAX, VEGFA, CASP2
14alpha lipoic acid449.2BAX, NOS2, CHAT, TXN, CAT, SOD1
152-methoxyestradiol44 59 2411.2HSPB1, BAX, HIF1A, SETD2, BCL2L1, PCNA
16bortezomib44 1110.1BAX, BAK1, VEGFA, BCL2L1, HSPB1, HIF1A
17pdtc449.1BCL2L1, SETD2, CAT, SOD1, HIF1A, NOS2
18peroxynitrite449.1GFAP, SOD1, CAT, CASP2, TXN, NOS2
194-hydroxynonenal44 2410.1NOS2, CAT, TXN, BAX, CHAT, SOD1
20celecoxib44 59 28 49 11 2414.0BAX, VEGFA, BAK1, PCNA, NOS2, HIF1A
21ascorbic acid44 249.9TXN, CASP2, CAT, PCNA, NOS2, SETD2
22paclitaxel44 49 1110.9BCL2L1, SETD2, GFAP, HIF1A, BAK1, BAX
23sodium nitroprusside448.9CHAT, CAT, SETD2, NOS2, PCNA, SOD1
24dutp448.9BCL2L1, GFAP, HSPB1, BAK1, BAX, PCNA
25sp 60012544 599.8BCL2L1, HIF1A, SETD2, HSPB1, BAX, CASP2
26docetaxel44 49 59 1111.8BCL2L1, SETD2, HIF1A, BAX, BAK1, VEGFA
27camptothecin44 59 1110.8BAX, BCL2L1, PCNA, CASP2, SETD2, BAK1
28mg 13244 599.8PCNA, VEGFA, HIF1A, BAX, BCL2L1, NOS2
29curcumin448.8HSPB1, CAT, NOS2, BAK1, BCL2L1, VEGFA
30sb 20358044 599.8CAT, HSPB1, VEGFA, BAX, HIF1A, CXCL12
31h2o2448.7SETD2, PCNA, BAK1, CASP2, HSPB1, CAT
32pd 98,059448.7BAX, HIF1A, SETD2, GFAP, CXCL12, CHAT
33ly294002448.7BCL2L1, SETD2, NOS2, HIF1A, IGFBP2, VEGFA
34arsenite44 249.6PCNA, SETD2, HIF1A, BAX, TXN, HSPB1
355fluorouracil448.5BCL2L1, HSPB1, VEGFA, BAX, BAK1, CASP2
36quercetin44 59 11 2411.4SOD1, BCL2L1, BAX, BAK1, HSPB1, NOS2
37oxygen44 249.3IGFBP2, BAX, BAK1, GFAP, NOS2, BCL2L1
38nitric oxide44 11 2410.3CHAT, NFKB1, BAK1, HIF1A, SOD1, CAT
39paraffin448.2BAK1, CASP2, BCL2L1, GFAP, PCNA, HSPB1
40doxorubicin44 49 1110.2TXN, HSPB1, CASP2, CAT, VEGFA, BAX
41etoposide44 49 59 1111.1HSPB1, BAK1, BCL2L1, SETD2, PCNA, HIF1A
42phosphatidylinositol448.1BCL2L1, HSPB1, KNG1, CHAT, IGFBP2, BAX
43n acetylcysteine448.0BCL2L1, SETD2, NOS2, PCNA, HIF1A, BAX
44genistein44 28 59 2 11 2412.9ADORA1, BCL2L1, NOS2, GFAP, CXCL12, PCNA
45actinomycin d447.9BCL2L1, SETD2, NOS2, CXCL12, HIF1A, BAK1
46dexamethasone44 49 28 1110.9TXN, HSPB1, CHAT, VEGFA, BAK1, HIF1A
47arginine447.8HSPB1, SOD1, KNG1, TXN, IGFBP2, HIF1A
48cisplatin44 49 59 1110.6BCL2L1, SETD2, GFAP, TXN, HSPB1, CASP2
49vegf447.6PCNA, VEGFA, CXCL12, BAX, HSPB1, TXN
50retinoic acid44 248.5CHAT, HSPB1, IGFBP2, CASP2, BCL2L1, BAX

GO Terms for genes affiliated with Retinal Ischemia

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Sources:
16Gene Ontology
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Cellular components related to Retinal Ischemia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1pore complexGO:0469309.9BAK1, BAX
2Bcl-2 family protein complexGO:0971369.7BCL2L1, BAX
3neuronal cell bodyGO:0430259.2TXN, SOD1, CHAT, ADORA1
4mitochondrionGO:0057398.2TXN, CASP2, SOD1, CHAT, NFKB1, BAX
5cytosolGO:0058297.1BCL2L1, TXN, HSPB1, CASP2, CAT, SOD1

Biological processes related to Retinal Ischemia according to GeneCards/GeneDecks:

(show all 32)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of transcription from RNA polymerase II promoter in response to hypoxiaGO:06141910.5VEGFA, HIF1A
2positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathwGO:03803310.4HSPB1, VEGFA
3relaxation of vascular smooth muscleGO:06008710.2SOD1, ADORA1
4B cell negative selectionGO:00235210.2BAK1, BAX
5post-embryonic camera-type eye morphogenesisGO:04859710.2BAX, BAK1
6establishment or maintenance of transmembrane electrochemical gradientGO:01024810.2BAX, BAK1
7positive regulation of endoplasmic reticulum unfolded protein responseGO:190010310.2BAX, BAK1
8B cell apoptotic processGO:00178310.2BAX, BAK1
9positive regulation of mitochondrial outer membrane permeabilizationGO:190103010.2BAK1, BAX
10reduction of endoplasmic reticulum calcium ion concentrationGO:03247110.1BAX, BAK1
11regulation of protein homodimerization activityGO:04349610.1BAK1, BAX
12regulation of protein heterodimerization activityGO:04349710.0BAK1, BAX
13activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome cGO:00863510.0BAX, BAK1
14response to axon injuryGO:04867810.0BAX, SOD1, TXN
15germ cell developmentGO:00728110.0BAX, CXCL12, BCL2L1
16myeloid cell homeostasisGO:00226210.0BAK1, BAX, SOD1
17vagina developmentGO:0600689.9BAX, BAK1
18cellular response to mechanical stimulusGO:0712609.9BAK1, NFKB1, CASP2
19positive regulation of angiogenesisGO:0457669.9HSPB1, VEGFA, HIF1A
20platelet degranulationGO:0025769.9VEGFA, KNG1, SOD1
21apoptotic signaling pathwayGO:0971909.9CASP2, BAX, BAK1, ADORA1
22negative regulation of intrinsic apoptotic signaling pathway in response to DNA damageGO:19022309.8BCL2L1, CXCL12
23release of cytochrome c from mitochondriaGO:0018369.8BAX, BAK1, BCL2L1
24response to hypoxiaGO:0016669.8CAT, VEGFA, HIF1A, NOS2, ADORA1
25mitochondrial fusionGO:0080539.8BAK1, BAX
26ovarian follicle developmentGO:0015419.8SOD1, VEGFA, BAX, BCL2L1
27negative regulation of neuron apoptotic processGO:0435249.7SOD1, BAX, HIF1A, BCL2L1
28intrinsic apoptotic signaling pathwayGO:0971939.7BAX, BAK1, BCL2L1
29regulation of mitochondrial membrane potentialGO:0518819.6BCL2L1, BAK1, BAX, SOD1
30regulation of mitochondrial membrane permeabilityGO:0469029.4BCL2L1, BAK1
31negative regulation of apoptotic processGO:0430669.4ADORA1, BCL2L1, NFKB1, VEGFA, CAT, HSPB1
32positive regulation of apoptotic processGO:0430659.2CASP2, SOD1, KNG1, BAX, BAK1, BCL2L1

Molecular functions related to Retinal Ischemia according to GeneCards/GeneDecks:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1BH3 domain bindingGO:0514349.7BAX, BCL2L1
2receptor bindingGO:0051029.5NOS2, CXCL12, KNG1, CAT
3enzyme bindingGO:0198999.2HIF1A, CAT, CASP2, TXN
4protein heterodimerization activityGO:0469828.9VEGFA, BAX, BAK1, HIF1A, BCL2L1, ADORA1
5protein homodimerization activityGO:0428038.7CAT, SOD1, VEGFA, NFKB1, BAX, BAK1
6identical protein bindingGO:0428028.4HSPB1, SOD1, VEGFA, BAX, BAK1, PCNA
7protein bindingGO:0055156.4ADORA1, TXN, HSPB1, CASP2, SOD1, KNG1

Products for genes affiliated with Retinal Ischemia

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  • Antibodies
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Sources for Retinal Ischemia

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet