MCID: RTN003
MIFTS: 48

Retinal Ischemia malady

Category: Eye diseases

Aliases & Classifications for Retinal Ischemia

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Aliases & Descriptions for Retinal Ischemia:

Name: Retinal Ischemia 35 11 50 13 68

Classifications:



External Ids:

Disease Ontology11 DOID:12510
ICD1030 H35.82
SNOMED-CT62 193427006, 26468004
ICD9CM32 362.84

Summaries for Retinal Ischemia

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MalaCards based summary: Retinal Ischemia is related to exudative vitreoretinopathy 3 and exudative vitreoretinopathy 4. An important gene associated with Retinal Ischemia is HIF1A (Hypoxia Inducible Factor 1 Alpha Subunit), and among its related pathways are Angiogenesis (WikiPathways) and Gemtuzumab ozogamicin Pathway, Pharmacokinetics/Pharmacodynamics. Affiliated tissues include eye, bone and endothelial, and related mouse phenotypes are Increased Nanog expression and Increased cell death HMECs cells.

Related Diseases for Retinal Ischemia

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Diseases related to Retinal Ischemia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 77)
idRelated DiseaseScoreTop Affiliating Genes
1exudative vitreoretinopathy 310.8
2exudative vitreoretinopathy 410.8
3exudative vitreoretinopathy 110.8
4exudative vitreoretinopathy 2, x-linked10.8
5transient cerebral ischemia10.8
6mini stroke10.8
7ischemia10.8
8retinitis10.8
9psychologic vaginismus10.4HIF1A, SETD2
10iridogoniodysgenesis and skeletal anomalies10.3HIF1A, VEGFA
11cutaneous leishmaniasis10.2TNF, VEGFA
12elane-related neutropenia10.2CASP2, TNF
13plasma protein metabolism disease10.2BAX, CASP3, TNF
14large intestine adenoma10.2CASP3, HIF1A, VEGFA
15verloove vanhorick brubakk syndrome10.1HIF1A, SETD2, VEGFA
16renal tubular transport disease10.1HIF1A, SETD2, VEGFA
17autoimmune polyendocrine syndrome10.1TNF, VEGFA
18amelogenesis imperfecta hypomaturation type10.1CASP3, VEGFA
19renal fibrosis10.1HIF1A, TNF, VEGFA
20neuronitis10.1
21hilar cholangiocellular carcinoma10.1CXCL12, HIF1A, VEGFA
22tendinosis10.1CAT, HIF1A, TNF
23endotheliitis10.1
24villous adenoma10.1CASP3, HIF1A, VEGFA
25atypical depressive disorder10.0CASP3, NFKB1, TNF
26gallbladder papillomatosis10.0CASP3, TNF, VEGFA
27tracheal disease10.0CASP3, HIF1A, VEGFA
28adrenal cortical carcinoma10.0BAX, CASP3, PCNA
29multiple system atrophy with orthostatic hypotension9.9CAT, SOD1
30cystadenoma9.9HIF1A, SETD2, TNF, VEGFA
31pylorus cancer9.9BAX, PCNA, VEGFA
32retinal vein occlusion9.8
33choroiditis9.8
34cpt deficiency, hepatic, type ia9.8CASP3, CXCL12, TNF, VEGFA
35neurofibromatosis, type 19.8
36ehlers-danlos syndrome, musculocontractural type9.8CXCL12, SOD1, TNF
37pseudoretinitis pigmentosa9.7CAT, SOD1, TNF
38t-cell lymphoma 1a9.7TNF, VEGFA
39gemistocytic astrocytoma9.7CASP3, KNG1, TNF, VEGFA
40angiomyolipoma9.7CASP3, SOD1, TNF
41chronic myocardial ischemia9.7CASP3, CXCL12, TNF, VEGFA
42temporal arteritis9.7
43cataract9.7
44central retinal artery occlusion9.7
45neovascular glaucoma9.7
46cerebritis9.7
47retinal artery occlusion9.7
48ocular hypertension9.7
49hypoxia9.7
50scarlet fever9.7SOD1, TNF

Comorbidity relations with Retinal Ischemia via Phenotypic Disease Network (PDN):


Hypertension, Essential

Graphical network of the top 20 diseases related to Retinal Ischemia:



Diseases related to retinal ischemia

Symptoms & Phenotypes for Retinal Ischemia

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GenomeRNAi Phenotypes related to Retinal Ischemia according to GeneCards Suite gene sharing:

26
idDescriptionGenomeRNAi Source AccessionScoreTop Affiliating Genes
1GR00371-A-39.5CASP2, PCNA, SETD2, VEGFA
2GR00103-A-09.1CASP2, CASP3, CAT, HIF1A, PCNA
3GR00104-A-09.0CASP2, CASP3, CAT, PCNA, TNF
4GR00250-A-37.9BAX, HIF1A, NFKB1, PCNA, SOD1
5GR00250-A-14.5BAX, CASP3, HIF1A, NFKB1, PCNA, SOD1

MGI Mouse Phenotypes related to Retinal Ischemia according to GeneCards Suite gene sharing:

41 (show all 16)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00030128.5CASP3, CXCL12, HSPB1, PCNA, TNF, VEGFA
2MP:00020068.5BAX, CAT, HIF1A, SOD1, TNF, VEGFA
3MP:00053828.5CASP3, HIF1A, NFKB1, SETD2, TNF, VEGFA
4MP:00053888.5BAX, CASP3, HIF1A, NFKB1, TNF, VEGFA
5MP:00053708.2CXCL12, HIF1A, NFKB1, SOD1, TNF, VEGFA
6MP:00053907.9BAX, CASP3, HIF1A, NFKB1, SOD1, TNF
7MP:00053897.7BAX, CASP2, CASP3, CXCL12, PCNA, SOD1
8MP:00053697.6BAX, CASP3, CXCL12, HIF1A, NFKB1, SOD1
9MP:00053797.0BAX, CASP2, CASP3, HIF1A, NFKB1, PCNA
10MP:00053766.6BAX, CASP3, CAT, HIF1A, HSPB1, NFKB1
11MP:00053846.4BAX, CASP2, CASP3, CAT, CXCL12, HIF1A
12MP:00036316.4BAX, CASP2, CASP3, CXCL12, HIF1A, NFKB1
13MP:00053876.1BAX, CASP2, CASP3, CXCL12, HIF1A, HSPB1
14MP:00053976.1BAX, CASP2, CASP3, CXCL12, HIF1A, HSPB1
15MP:00053785.8BAX, CASP3, HIF1A, HSPB1, KNG1, NFKB1
16MP:00107685.6BAX, CASP2, CASP3, CAT, CXCL12, HIF1A

Drugs & Therapeutics for Retinal Ischemia

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Drugs for Retinal Ischemia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 201)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Latanoprostapproved, investigationalPhase 4197130209-82-45282380, 5311221
Synonyms:
130209-82-4
AC1NSK8Q
AR-202
Ambap130209-82-4
CHEBI:6384
CHEMBL1051
CID5311221
CPD000466354
Catioprost
D00356
HMS2051H11
HMS2089J17
Isopropyl (5Z,9alpha,11alpha,15R)-9,11,15-trihydroxy-17-phenyl-18,19,20-trinor-prost-5-en-1-oate
Isopropyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((3R)-3-hydroxy-5-phenylpentyl)cyclopentyl)-5-heptenoate
Jsp001835
L1167_SIGMA
Latanoprost
Latanoprost (JAN/USAN/INN)
Latanoprostum
MLS000759468
MLS001424106
 
MolPort-003-942-862
Nova-21027
PHXA-41
PhXA 41
PhXA34 [as 15(R,S)-isomer]
PhXA41
Propan-2-yl (5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl}hept-5-enoate
S1254_Selleck
SAM001246671
SMR000466354
TL8000716
XA-41
XA41
Xalatan
Xalatan (TN)
Xalatan Fixed Flow Device
ZINC12468792
isopropyl (5Z,9alpha,11alpha,15R)-9,11,15-trihydroxy-17-phenyl-18,19,20-trinorprost-5-en-1-oate
latanoprost
latanoprost free acid
propan-2-yl (5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl}hept-5-enoate
propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoate
2
Bevacizumabapproved, investigationalPhase 4, Phase 3, Phase 2, Phase 11968216974-75-3
Synonyms:
216974-75-3
Avastin
Avastin (TN)
Bevacizumab
Bevacizumab (genetical recombination)
 
Bevacizumab (genetical recombination) (JAN)
D06409
R-435
anti-VEGF monoclonal antibody
antiVEGF
bevacizumab
3
DorzolamideapprovedPhase 467120279-96-13154, 5284549
Synonyms:
(4S,6S)-4-(ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide
(4S,6S)-4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide
(4S,6S)-4-Ethylamino-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda*6*-thieno[2,3-b]thiopyran-2-sulfonic acid amide
(4S,trans)-4-(Ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide
(4S,trans)-4-(ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide
(4S-TRANS)-4-(ETHYLAMINO)-5,6-DIHYDRO-6-METHYL-4H-THIENO(2,3-B)THIOPYRAN-2-SULFONAMIDE-7,7-DIOXIDE
(4S-trans)-4-(ETHYLAMINO)-5,6-dihydro-6-methyl-4H-thieno(2,3-b)thiopyran-2-sulfonamide-7,7-dioxide
120279-96-1
1cil
4-Ethylamino-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda*6*-thieno[2,3-b]thiopyran-2-sulfonic acid amide
4-Ethylamino-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda6-thieno[2,3-b]thiopyran-2-sulfonic acid amide
4S,6S-Dorzolamide
AB00514687
AC1NR4NP
BIDD:GT0306
BPBio1_001377
BRD-K48617017-003-03-1
BSPBio_001252
C06969
CHEBI:4702
 
CHEMBL218490
CID5284549
D07871
DB04507
Dorzolamid
Dorzolamida
Dorzolamide
Dorzolamide (DZA)
Dorzolamide (INN)
Dorzolamidum
HMS2089O06
MolPort-005-941-739
Prestwick0_001116
Prestwick1_001116
Prestwick2_001116
Prestwick3_001116
SPBio_003116
STK645522
Trusopt
Trusopt (TN)
dorzolamide
4
TimololapprovedPhase 425226839-75-833624, 5478
Synonyms:
(-)-3-Morpholino-4-(3-tert-butylamino-2-hydroxypropoxy)-1,2,5-thiadiazole
(2S)-1-((1,1-dimethylethyl)amino)-3-((4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl)oxy)-2-propanol
(2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol
(2S)-1-[(1,1-dimethylethyl)amino]-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol
(S)-1-(1,1-(Dimethylethyl)amino)-3-((4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl)oxy)-2-propanol
(S)-1-(tert-Butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-ol
(S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol
(S)-timolol
131628-37-0
194288-09-0
26839-75-8
26921-17-5 (maleate (1:1) salt)
AB00513729
AC1L1PYN
AC1Q59QM
Apo-Timol
Apo-Timop
Aquanil
BIDD:GT0073
BPBio1_001008
BRD-K08806317-050-03-6
BSPBio_000916
Betim
Betimol
Betimol (TN)
Blocadren
C07141
C13H24N4O3S
CAS-26921-17-5
CHEBI:9599
CHEMBL499
CID33624
CPD001456519
D08600
DB00373
DB08625
EINECS 248-032-6
HMS2089I11
HSDB 6533
Istalol
L-714,465
LS-122231
Lopac-T-6394
Lopac0_001189
MK-950
NCGC00016038-01
 
NCGC00016038-02
NCGC00016798-01
NCGC00016798-07
NCGC00022033-02
NCGC00022033-04
NCGC00022033-05
Novo-Timol
Nu-Timolol
Oprea1_640981
Optimol
Phoxal-timolol
Prestwick0_000948
Prestwick1_000948
Prestwick2_000948
Prestwick3_000948
Proflax
S(-)-Timolol maleate
S-(-)-3-(3-tert-Butylamino-2-hydroxypropoxy)-4-morpholino-1,2,5-thiadiazole
SAM002564238
SPBio_003075
ST072193
TIM
Temserin
Tenopt
Tim-AK
Timacar
Timacor
Timolol
Timolol (INN)
Timolol (TN)
Timolol GFS
Timolol Maleate, (1:1) Salt
Timolol [USAN]
Timolol anhydrous
Timolol maleate
Timololo
Timololum
Timololum [INN-Latin]
Timopic
Timoptic
Timoptic OcuDose
Timoptic in Ocudose
Timoptic-XE
Timoptol
Tocris-0649
UNII-817W3C6175
timolol
5
Aspirinapproved, vet_approvedPhase 4, Phase 3111250-78-22244
Synonyms:
11126-35-5
11126-37-7
1oxr
2-(ACETYLOXY)benzoic acid
2-(Acetyloxy)benzoate
2-(Acetyloxy)benzoic acid
2-Acetoxybenzenecarboxylic acid
2-Acetoxybenzoate
2-Acetoxybenzoic acid
2-Carboxyphenyl acetate
2349-94-2
26914-13-6
50-78-2
8-hour Bayer
98201-60-6
A 5376
A.S.A
A.S.A.
A.S.A. Empirin
A.S.A. empirin
A2093_SIGMA
A3160_SIGMA
A5376_SIGMA
A6810_SIGMA
AB1003266
AC 5230
AC1L1D8U
AC1Q1LA0
ACETYLSALICYLIC ACID
AI3-02956
AIN
AKOS000118884
ASA
Acenterine
Acesal
Acetal
Acetard
Aceticyl
Acetilsalicilico
Acetilum acidulatum
Acetisal
Acetol
Acetonyl
Acetophen
Acetosal
Acetosalic acid
Acetosalin
Acetoxybenzoic acid
Acetylin
Acetylsal
Acetylsalicylate
Acetylsalicylic acid
Acetylsalicylsaeure
Acetylsalicylsaure
Acetylsalycilic acid
Acetyonyl
Acetysal
Acetysalicylic acid
Acide 2-(acetyloxy)benzoique
Acide acetylsalicylique
Acide acétylsalicylique
Acido O-acetil-benzoico
Acido acetilsalicilico
Acidum acetylsalicylicum
Acimetten
Acisal
Acylpyrin
Adiro
Aloxiprimum
Asacard
Asagran
Asatard
Ascoden-30
Aspalon
Aspec
Aspergum
Aspir-Mox
Aspirdrops
Aspirin
Aspirin (JP15/USP)
Aspirin [BAN:JAN]
Aspirina 03
Aspirine
Asprin
Aspro
Aspro Clear
Asteric
Azetylsalizylsaeure
Azetylsalizylsäure
BIDD:GT0118
BRN 0779271
Bay-e-4465
Bayer
Bayer Aspirin 8 Hour
Bayer Buffered
Bayer Extra Strength Aspirin For Migraine Pain
Bayer Plus
Benaspir
Bi-prin
Bialpirina
Bialpirinia
Bufferin
C01405
CCRIS 3243
CHEBI:15365
CHEMBL25
CID2244
Caprin
Cardioaspirin
Cardioaspirina
Cemirit
Claradin
Clariprin
Colfarit
Contrheuma retard
Coricidin
Crystar
D00109
D001241
DB00945
Decaten
Delgesic
Dispril
DivK1c_000555
Dolean pH 8
Duramax
ECM
EINECS 200-064-1
EU-0100038
Easprin
Easprin (TN)
Ecolen
Ecotrin
Empirin
Empirin with Codeine
Endosprin
Endydol
 
Entericin
Enterophen
Enterosarein
Enterosarine
Entrophen
Extren
Globentyl
Globoid
HMS1920E13
HMS2090G03
HMS2091K13
HMS501L17
HSDB 652
Helicon
I14-7505
IDI1_000555
Idragin
Istopirin
KBio1_000555
KBio2_001725
KBio2_002271
KBio2_004293
KBio2_004839
KBio2_006861
KBio2_007407
KBio3_002149
KBio3_002751
KBioGR_000398
KBioGR_002271
KBioSS_001725
KBioSS_002272
Kapsazal
Kyselina 2-acetoxybenzoova
Kyselina acetylsalicylova
LS-143
Levius
Lopac-A-5376
Lopac0_000038
MLS001055329
MLS001066332
MLS001336045
MLS001336046
Magnecyl
Measurin
Medisyl
Micristin
MolPort-000-871-622
NCGC00015067-01
NCGC00015067-04
NCGC00015067-09
NCGC00090977-01
NCGC00090977-02
NCGC00090977-03
NCGC00090977-04
NCGC00090977-05
NCGC00090977-06
NCGC00090977-07
NCI60_002222
NINDS_000555
NSC 27223
NSC27223
NSC406186
Neuronika
Novid
Nu-seals
Nu-seals aspirin
O-(Acetyloxy)benzoate
O-(Acetyloxy)benzoic acid
O-Acetoxybenzoate
O-Acetoxybenzoic acid
O-Acetylsalicylic acid
O-Carboxyphenyl acetate
O-accetylsalicylic acid
O-acetylsalicylic acid
PL-2200
Persistin
Pharmacin
Pirseal
Polopirin
Polopiryna
Premaspin
R16CO5Y76E [UNII]
Rheumin tabletten
Rheumintabletten
Rhodine
Rhonal
Ronal
S-211
SMR000059138
SP 189
SPBio_001838
SPECTRUM1500130
ST075414
Salacetin
Salcetogen
Saletin
Salicylic acid acetate
Salicylic acid, acetate
Salospir
Solfrin
Solprin
Solprin acid
Solpyron
Solupsan
Spectrum2_001899
Spectrum3_001295
Spectrum4_000099
Spectrum5_000740
Spectrum_001245
Spira-Dine
St. Joseph
St. Joseph Aspirin for Adults
Supac
Tasprin
Temperal
Toldex
Triaminicin
Triple-sal
UNII R16CO5Y76E
UNII-R16CO5Y76E
UNII=R16CO5Y76E
UNM-0000306102
Vanquish
WLN: QVR BOV1
XAXA
Xaxa
Yasta
ZORprin
aspirin
cMAP_000006
component of Midol
component of Synirin
nchem.859-comp6
o-Acetoxybenzoic acid
o-Carboxyphenyl acetate
o-acetoxybenzoic acid
o-carboxyphenyl acetate
ácido acetilsalicílico
6
DipyridamoleapprovedPhase 48058-32-23108
Synonyms:
2,6-Bis(diethanolamine)-4,8-dipiperidinopyrimido[5,4-d]pyrimidine
2,6-Bis(diethanolamino)-4,8-dipiperidinopyrimido(5,4-d)pyrimidine
2,6-Bis(diethanolamino)-4,8-dipiperidinopyrimido[5,4-d]pyrimidine
4-26-00-03840 (Beilstein Handbook Reference)
58-32-2
AB00051974
AC-18100
AC1L1F6T
AC1Q7CXU
AC1Q7CXW
AC1Q7CXX
AKOS000509426
Agilease
Anginal
Antistenocardin
Apo-Dipyridamole
Apo-Dipyridamole Fc
Apo-Dipyridamole Sc
Apotex Brand of Dipyridamole
Apricor
Ashbourne Brand of Dipyridamole
BAS 00818792
BIM-0050449.0001
BPBio1_000270
BRD-K86301799-001-04-1
BRN 0068373
BSPBio_000244
BSPBio_001554
BSPBio_001924
Belmac Brand of Dipyridamole
Berlin Chemie Brand of Dipyridamole
Berlin-Chemie Brand of Dipyridamole
Bio-0173
Boehringer Ingelheim Brand of Dipyridamole
C24H40N8O4
CAS-58-32-2
CHEBI:4653
CHEMBL932
CID3108
CPD000058382
Cardioflux
Cardoxil
Cardoxin
Cerebrovase
Chilcolan
Cleridium
Cleridium 150
Coribon
Coridil
Coronarine
Corosan
Coroxin
Curantil
Curantyl
D 9766
D00302
D004176
D2274
D9766_SIGMA
DB00975
Dipiridamol
Dipiridamol [INN-Spanish]
Dipyramidole
Dipyridamine
Dipyridamol
Dipyridamole (JP15/USP/INN)
Dipyridamole [USAN:INN:BAN:JAN]
Dipyridamolum
Dipyridamolum [INN-Latin]
Dipyridan
Dipyudamine
DivK1c_000696
Dypyridamol
EINECS 200-374-7
EU-0100464
Gulliostin
HMS1568M06
HMS1791N16
HMS1920I10
HMS1989N16
HMS2089N15
HMS2091O18
 
HMS502C18
IDI1_000696
IPRAD Brand of Dipyridamole
Iv Persantine
Justpertin
KBio1_000696
KBio2_001484
KBio2_004052
KBio2_006620
KBio3_001144
KBioGR_001123
KBioSS_001484
Kurantil
LS-66732
Lopac-D-9766
Lopac0_000464
MLS000028420
MLS001076306
MLS001333724
Miosen
MolPort-001-792-504
NCGC00015385-01
NCGC00015385-02
NCGC00015385-03
NCGC00015385-07
NCGC00015385-15
NCGC00023914-02
NCGC00023914-04
NCGC00023914-05
NCGC00023914-06
NCGC00023914-07
NCGC00023914-08
NCGC00023914-09
NCGC00023914-10
NCGC00023914-11
NCI60_005689
NINDS_000696
NSC 515776
NSC-515776
NSC515776
Natyl
Novo-Dipiradol
Novopharm Brand of Dipyridamole
Peridamol
Permiltin
Permole, Persantine, Dipyridan, Dipyridamole
Persantin
Persantine
Persantine (TN)
Piroan
Prandiol
Prandiol 75
Prestwick0_000142
Prestwick1_000142
Prestwick2_000142
Prestwick3_000142
Prestwick_145
Protangix
RA 8
RA-8
S1867_Selleck
S1895_Selleck
SAM002264609
SMP2_000208
SMR000058382
SPBio_001003
SPBio_002183
SPECTRUM1500259
Spectrum2_000972
Spectrum3_000402
Spectrum4_000522
Spectrum5_000839
Spectrum_001004
Stenocardil
Stenocardiol
Stimolcardio
Tocris-0691
UNII-64ALC7F90C
UPCMLD-DP072
UPCMLD-DP072:001
Usaf Ge-12
WLN: T66 BN DN GN INJ CCN HCN E- AT6NTJ B2Q F2Q& J- AT6NTJ B2Q F2Q
ZINC00643046
dipyridamole
7
RanibizumabapprovedPhase 4, Phase 3, Phase 1, Phase 2474347396-82-1459903
Synonyms:
347396-82-1
D05697
Lucentis
Lucentis (TN)
 
Ranibizumab
Ranibizumab (USAN/INN)
Ranibizumab (genetical recombination)
Ranibizumab (genetical recombination) (JAN)
ranibizumab
rhuFab V2
8
Tadalafilapproved, investigationalPhase 4149171596-29-5110635
Synonyms:
(6R,12AR)-2,3,6,7,12,12a-hexahydro-2-methyl-6-(3,4-(methylenedioxy)phenyl) pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione
(6R,12aR)-2,3,6,7,12,12a-Hexahydro-2-methyl-6-(3,4-(methylenedioxy)phenyl) pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione
(6R,12aR)-2,3,6,7,12,12a-Hexahydro-2-methyl-6-(3,4-methylenedioxyphenyl)pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione
(6R-trans)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione
171596-29-5
1xoz
6-BENZO[1,3]dioxol-5-yl-2-methyl-2,3,6,7,12,12a-hexahydro-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione
AC1L380B
ADCIRCA
Acdirca
Adcirca
C429886
CHEBI:41488
CHEMBL779
CID110635
CPD000466321
Cialis
Cialis (TN)
Cialis, GF 196960, IC 351, ICOS 351, Tadalafil
D02008
DB00820
FT-0080116
GF 196960
GF-196960
 
HMS2051N17
HSDB 7303
IC 351
IC-351
ICOS 351
Ic351
KS-1117
LS-186558
LS-187015
LS-187770
Lilly brand of tadalafil
MLS000759426
MLS001165782
MLS001195644
MLS001424132
MolPort-002-885-864
S1512_Selleck
SAM001246586
SMR000466321
Tadalafil
Tadalafil (JAN/USAN/INN)
Tadalafil [USAN]
Tadanafil
UNII-742SXX0ICT
ZINC03993855
9
Cholineapproved, nutraceuticalPhase 414862-49-7305
Synonyms:
(2-Hydroxyethyl)trimethyl ammonium
(2-Hydroxyethyl)trimethylammonium
(beta-hydroxyethyl)trimethylammonium
2-Hydroxy-N,N,N-trimethyl-ethanaminium
2-Hydroxy-N,N,N-trimethylethanaminium
Bilineurine
Biocolina
Biocoline
Choline
Choline cation
 
Choline ion
Cholinum
Hepacholine
Hormocline
Lipotril
N,N,N-Trimethylethanol-ammonium
N,N,N-Trimethylethanolammonium
N,N,N-trimethylethanol-ammonium
N-trimethylethanolamine
Neocolina
Paresan
trimethylethanolamine
10Lipid Regulating AgentsPhase 42702
11Hypolipidemic AgentsPhase 42721
12Anti-Inflammatory AgentsPhase 4, Phase 3, Phase 2, Phase 110355
13Rosuvastatin CalciumPhase 4459147098-20-2
14Angiogenesis InhibitorsPhase 4, Phase 3, Phase 2, Phase 14143
15Peripheral Nervous System AgentsPhase 4, Phase 3, Phase 2, Phase 122776
16Hydroxymethylglutaryl-CoA Reductase InhibitorsPhase 41956
17Calcium, DietaryPhase 45525
18Angiogenesis Modulating AgentsPhase 4, Phase 3, Phase 2, Phase 14072
19Adrenergic AntagonistsPhase 4, Phase 1, Phase 21535
20Adrenergic AgentsPhase 4, Phase 1, Phase 25140
21Adrenergic beta-AntagonistsPhase 4, Phase 1, Phase 21154
22Anti-Arrhythmia AgentsPhase 4, Phase 1, Phase 22969
23AntimetabolitesPhase 411774
24Anticholesteremic AgentsPhase 41983
25Neurotransmitter AgentsPhase 4, Phase 3, Phase 1, Phase 217734
26Antihypertensive AgentsPhase 4, Phase 3, Phase 1, Phase 24095
27Carbonic Anhydrase InhibitorsPhase 4179
28Platelet Aggregation InhibitorsPhase 4, Phase 32419
29Phosphodiesterase InhibitorsPhase 4, Phase 21254
30Phosphodiesterase 5 InhibitorsPhase 4571
31ImmunoglobulinsPhase 46045
32AntibodiesPhase 46045
33Vasodilator AgentsPhase 4, Phase 2, Phase 13438
34AntipyreticsPhase 4, Phase 31534
35AnalgesicsPhase 4, Phase 311287
36Cytidine Diphosphate CholinePhase 429
37Nootropic AgentsPhase 4701
38Analgesics, Non-NarcoticPhase 4, Phase 36260
39Anti-Inflammatory Agents, Non-SteroidalPhase 4, Phase 34295
40Cyclooxygenase InhibitorsPhase 4, Phase 32778
41Antirheumatic AgentsPhase 4, Phase 310627
42Fibrinolytic AgentsPhase 4, Phase 32317
43Vardenafil DihydrochloridePhase 476
44Sildenafil CitratePhase 4323171599-83-0
45
Methylprednisoloneapproved, vet_approvedPhase 3, Phase 1, Phase 2115383-43-26741
Synonyms:
(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
(6a,11b)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6α,11β)-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione
.DELTA.1-6.alpha.-Methylhydrocortisone
1-Dehydro-6alpha-methylhydrocortisone
1-dehydro-6alpha-Methylhydrocortisone
1-dehydro-6α-methylhydrocortisone
11-beta,17,21-Trihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione
11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methyl-1,4-pregnadiene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
121673-01-6
4-08-00-03498 (Beilstein Handbook Reference)
46436_FLUKA
46436_RIEDEL
570-35-4
6 Methylprednisolone
6-Methylprednisolone
6-alpha-Methylprednisolone
6.alpha.-Methylprednisolone
6923-42-8
6alpha-Methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione
6alpha-Methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
6alpha-Methylprednisolone
6alpha-methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
83-43-2
AC1L1N7A
Artisone-Wyeth
Artisone-wyeth
BPBio1_000174
BRD-K35240538-001-03-1
BRN 2340300
BSPBio_000158
Besonia
Bio-0658
CHEBI:6888
CHEMBL650
CID6741
CPD000058330
D00407
D008775
DB00959
Depo-Medrol (acetate)
Dopomedrol
EINECS 201-476-4
Esametone
Firmacort
HMS1568H20
HMS2090B13
HSDB 3127
LMST02030178
LS-118498
Lemod
M0639_SIGMA
M1665
MEPRDL
MLS000028541
MLS001148159
MLS002207191
Medesone
Medixon
Medlone 21
 
Medrate
Medrol
Medrol (TN)
Medrol Adt Pak
Medrol Dosepak
Medrol adt pak
Medrol dosepak
Medrol, Solu-Medrol, Medrone, Methylprednisolone
Medrone
Mesopren
Metastab
Methyleneprednisolone
Methylprednisolon
Methylprednisolone
Methylprednisolone (JP15/USP/INN)
Methylprednisolone [USAN:INN:BAN:JAN]
Methylprednisolone, 6-alpha
Methylprednisolonum
Methylprednisolonum [INN-Latin]
Metilbetasone
Metilprednisolona
Metilprednisolona [INN-Spanish]
Metilprednisolone
Metilprednisolone [DCIT]
Metilprednisolone [Dcit]
Metipred
Metrisone
Metrocort
Metysolon
Moderin
MolPort-002-528-554
NCGC00022735-03
NCI60_001657
NSC-19987
NSC19987
Nirypan
Noretona
Predni N Tablinen
Prednol- L
Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy-6alpha-methyl- (8CI)
Prestwick0_000279
Prestwick1_000279
Prestwick2_000279
Prestwick3_000279
Prestwick_622
Promacortine
Reactenol
S1733_Selleck
SAM002589984
SMR000058330
SPBio_002377
Sieropresol
Solomet
Summicort
Suprametil
U 7532
UNII-X4W7ZR7023
Urbason
Urbasone
Wyacort
ZINC03875560
delta(1)-6alpha-Methylhydrocortisone
delta(sup 1)-6-alpha-Methylhydrocortisone
methylprednisolone
methylprenisolone
46
Prednisoloneapproved, vet_approvedPhase 3, Phase 1, Phase 2115350-24-85755
Synonyms:
(11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione
.DELTA.1-Cortisol
.DELTA.1-Dehydrocortisol
.DELTA.1-Dehydrohydrocortisone
.DELTA.1-Hydrocortisone
.delta.-Cortef
.delta.-Stab
1,2-Dehydrohydrocortisone
1,4-Pregnadiene-11beta,17alpha,21-triol-3,20-dione
1,4-Pregnadiene-3,20-dione-11beta,17alpha,21-triol
1-Dehydrocortisol
1-Dehydrohydrocortisone
3,20-dioxo-11beta,17alpha,21-Trihydroxy-1,4-pregnadiene
46656_FLUKA
46656_RIEDEL
50-24-8
58201-11-9
8056-11-9
AC-1773
AC1L1L2E
Ak-Pred
Ak-Tate
Alphadrol
Articulose-50
BPBio1_000164
BRD-K98039984-001-03-0
BRN 1354103
BSPBio_000148
Bio-0666
Bubbli-Pred
C07369
CCRIS 980
CHEBI:8378
CHEMBL131
CID5755
CO-Hydeltra
CPD000718761
Co-Hydeltra
Codelcortone
Cordrol
Cortalone
Cotogesic
Cotolone
D00472
D011239
DB00860
Decaprednil
Decortin H
Delcortol
Delta F
Delta(1)-dehydrohydrocortisone
Delta-Cortef
Delta-Cortef (TN)
Delta-Ef-Cortelan
Delta-Stab
Delta-stab
Deltacortenol
Deltacortril
Deltacortril Enteric
Deltahydrocortisone
Deltasolone
Deltisilone
Depo-Medrol
Derpo PD
Derpo Pd
Dexa-Cortidelt Hostacortin H
Dexa-Cortidelt hostacortin H
Di Adreson F
Di-Adreson F
Di-Adreson-F
Di-adreson F
DiAdresonF
Dicortol
Donisolone
Dydeltrone
EINECS 200-021-7
Eazolin D
Econopred
Econopred Plus
Erbacort
Erbasona
Estilsona
Fernisolone
Fernisolone P
Fernisolone-P
Flamasone
HMS1568H10
HMS2090J05
HSDB 3385
Hostacortin H
Hydeltra
Hydeltra-Tba
Hydeltrasol
Hydeltrone
Hydrodeltalone
Hydrodeltisone
Hydroretrocortin
Hydroretrocortine
I-Pred
Inflamase Forte
Inflamase Mild
K 1557
Key-Pred
Klismacort
LMST02030179
LS-7669
Lentosone
Lite Pred
M-Predrol
 
MLS001304083
MLS002154250
MLS002207037
Medrol
Medrol Acetate
Metacortandralone
Methylprednisolone Acetate
Meti-Derm
Meticortelone
Metreton
MolPort-002-507-147
NCGC00179649-01
NSC 9120
NSC9120
NSC9900
Neo-Delta-Cortef
Nisolone
Nor-Pred T.B.A.
Ocu-Pred
Ocu-Pred Forte
Ophtho-Tate
Orapred
P0152_SIGMA
P0637
P6004_SIGMA
PRDL
PRED-G
Panafcortelone
Paracortol
Paracotol
Pediapred
Poly-Pred
Precortalon
Precortancyl
Precortilon
Precortisyl
Pred Forte
Pred Mild
Predair
Predair A
Predair Forte
Predalone 50
Predalone T.B.A.
Predate
Predate Tba
Predate-50
Predcor-25
Predcor-50
Predcor-Tba
Predisolone Sodium Phosphate
Predne-Dome
Prednelan
Predni-Dome
Prednicen
Predniliderm
Predniretard
Prednis
Prednisolona
Prednisolona [INN-Spanish]
Prednisolone (JP15/USP/INN)
Prednisolone (anhydrous)
Prednisolone Acetate
Prednisolone Sodium Phosphate
Prednisolone Tebutate
Prednisolone [INN:BAN:JAN]
Prednisolonum
Prednisolonum [INN-Latin]
Predonin
Predonine
Prelone
Prenolone
Prestwick0_000274
Prestwick1_000274
Prestwick2_000274
Prestwick3_000274
Prestwick_404
Rolisone
S1737_Selleck
SAM002264639
SMR000718761
SPBio_002367
Scherisolon
Solone
Steran
Sterane
Sterolone
Supercortisol
UNII-9PHQ9Y1OLM
Ulacort
Ultra Pred
Ultracorten H
Ultracortene H
Ultracortene-H
Ultracortene-Hydrogen
Ultracortene-hydrogen
ZINC03833821
component of Ataraxoid
component of K-Predne-Dome
delta(1)-Cortisol
delta(1)-Dehydrocortisol
delta(1)-Dehydrohydrocortisone
delta(1)-Hydrocortisone
delta(sup 1)-Cortisol
delta(sup 1)-Dehydrocortisol
delta(sup 1)-Dehydrohydrocortisone
delta(sup 1)-Hydrocortisone
delta-dehydrocortisol
delta-dehydrohydrocortisone
delta-hydrocortisone
prednisolone
47
VorapaxarapprovedPhase 315618385-01-6
Synonyms:
Carbamic acid, N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(E)-2-[5-(3-fluorophenyl)-2-pyridinyl]ethenyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]-, ethyl ester
 
Carbamic acid, [(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)-2- pyridinyl]ethenyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]-, ethyl ester
Ethyl N-[(3R,3aS,4S,4aR,7R,8aR,9aR)-4-[(E)-2-[5-(3-fluorophenyl)-2-pyridyl]vinyl]-3-methyl-1-oxo-3a,4,4a,5,6,7,8,8a,9,9a-decahydro-3H-benzo[f]isobenzofuran-7-yl]carbamate
[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-{(E)-2-[5-(3-Fluorophényl)-2-pyridinyl]vinyl}-1-méthyl-3-oxododécahydronaphto[2,3-c]furan-6-yl]carbamate d'éthyle
48
Irbesartanapproved, investigationalPhase 3101138402-11-63749
Synonyms:
138402-11-6
2-Butyl-3-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-1,3-diazaspiro(4.4)non-1-en-4-one
2-Butyl-3-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]1,3-diaza-spiro[4.4]non-1-en-4-one
2-Butyl-3-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1,3-diazaspiro[4.4]non-1-en-4-one
2-butyl-3-[ p -( o -1 H -tetrazol-5-ylphenyl)benzyl]-1,3-diazaspiro[4,4]non-1-en-4-one
2-butyl-3-[2'-(1h-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1,3-diaza-spiro[
2-butyl-3-[2'-(1h-tetrazol-5-yl)biphenyl-4-ylmethyl]1,3-diaza-spiro[
2-butyl-3-[p-(o-1H-tetrazol-5-ylphenyl)benzyl]-1,3-diazaspiro[4.4]non-1-en-4-one
2-butyl-3-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-1,3-diazaspiro[4.4]non-1-en-4-one
2-butyl-3-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1,3-diazaspiro[4.4]non-1-en-4-one
2-n-butyl-3-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-1,3-diazaspiro(4,4)non-1-en-4-one
8-butyl-7-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-7,9-diazaspiro[4.4]non-8-en-6-one
AC-537
AC1L1GMK
Aprovel
Avalide
Avapro
Avapro (TN)
BIDD:GT0347
BMS 186295
BMS Brand of Irbesartan
BMS-186295
BMS-186295, SR-47436, Aprovel, Karvea, Irbesartan
BRD-K60038276-001-02-5
BSPBio_002687
Bio-0053
Bristol Myers Brand of Irbesartan
C07469
C081309
C25H28N6O
CHEBI:5959
CHEMBL1513
CID3749
CPD000466306
D00523
DB01029
HMS1922J05
HMS2051L08
HMS2093E16
 
I06-0690
Irbesarran
Irbesartan
Irbesartan (JAN/USAN/INN)
Irbesartan [USAN:INN]
Irbesartan [Usan:Inn]
Irbetan
Jsp002315
KBio2_002231
KBio2_004799
KBio2_007367
KBio3_001907
KBioGR_001603
KBioSS_002231
Karvea
L000319
LS-60064
Lrbesartan
MLS000759408
MLS001424099
MolPort-003-666-550
NCGC00095122-01
NCGC00095122-02
NCGC00095122-03
S1507_Selleck
SAM001246548
SMR000466306
SPBio_001889
SPECTRUM1504259
SR 47436
SR-47436
STK645362
Sanofi Winthrop Brand of Irbesartan
Spectrum2_001675
Spectrum3_000994
Spectrum4_001122
Spectrum5_001288
Spectrum_001751
TL8000875
UNII-J0E2756Z7N
irbesartan
49
Triamcinoloneapproved, vet_approvedPhase 3, Phase 2482124-94-731307
Synonyms:
(8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11,16,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
11-beta,16-alpha,17-alpha,21-Tetrahydroxy-9-alpha-fluoro-1,4-pregnadiene-3,20-dione
11.Beta.,16.alpha.,17.alpha., 21-Tetrahydroxy-9.alpha.-fluoro-1,4-pregnadiene-3,20-dione
11.beta.,16.alpha.,17.alpha.,21-Tetrahydroxy-9.alpha.-fluoro-1,4-pregnadiene-3,20-dione
11β,16α,17α,21-tetrahydroxy-9α-fluoro-1,4-pregnadiene-3,20-dione
124-94-7
4-08-00-03629 (Beilstein Handbook Reference)
83474-03-7
9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9-Fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9-alpha-Fluoro-11-beta,16-alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9-alpha-Fluoro-16-alpha-hydroxyprednisolone
9-fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9.Alpha.-Fluoro-11.beta.,16.alpha.,17,21-tetrahy
9.Alpha.-Fluoro-11.beta.,16.alpha.,17.alpha., 21-tetrahydroxypregna-1,4-diene-3,20-d
9.alpha.-Fluoro-11.beta.,16.alpha.,17,21-tetrahydroxy-1,4-pregnadiene-3,20-dione
9.alpha.-Fluoro-11.beta.,16.alpha.,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9.alpha.-Fluoro-11.beta.,16.alpha.,17.alpha.,21-tetrahydroxypregna-1,4-diene-3,20-dione
9.alpha.-Fluoro-16.alpha.-hydroxyprednisolone
9alpha-Fluoro-11beta,16alpha,17,21-tetrahydroxy-1,4-pregnadiene-3,20-dione
9alpha-Fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9alpha-Fluoro-16alpha-hydroxyprednisolone
9α-fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9α-fluoro-11β,16α,17α,21-tetrahydroxypregna-1,4-diene-3,20-dione
9α-fluoro-16α-hydroxyprednisolone
AC-2072
AC1L1LDH
AC1Q5HJC
Adcortyl
Aristocort
Aristocort A
Aristocort Tablets
Aristogel
Aristospan
Azmacort
BPBio1_000154
BRD-K77554836-001-03-3
BRN 2341955
BSPBio_000140
Bio-0662
C21H27FO6
CHEMBL1451
CID31307
CL 19823
Celeste
Cinolone
Cinolone-T
D00385
D014221
DB00620
Delphicort
EINECS 204-718-7
EU-0101179
Fluoxiprednisolone
Fluoxyprednisolone
Flutex
Fougera
HMS1568G22
HMS2090D12
HSDB 3194
Kenacort
Kenacort (TN)
Kenacort-A
Kenacort-AG
Kenacort-Ag
Kenalog
Kenalog in Orabase
Kenalog-10
Kenalog-40
Kenalog-H
LS-698
Ledercort
Lopac0_001179
 
MLS000028542
MLS001066543
MLS002695935
MolPort-002-528-981
Mycolog
NCGC00021580-03
NCGC00021580-04
NCGC00021580-05
NCGC00021580-06
NCGC00021580-07
NCI60_000750
NSC 13397
NSC13397
Nasacort
Nasacort Aq
Nasacort Hfa
Omcilon
Omicilon
Oracort
Oralone
Orion
Polcortolon
Pregna-1,4-diene-3,20-dio
Pregna-1,4-diene-3,20-dione, 9-fluoro-11,16,17,21-tetrahydroxy-, (11beta,16alpha)
Pregna-1,4-diene-3,20-dione, 9-fluoro-11beta,16alpha,17,21-tetrahydroxy- (8CI)
Prestwick0_000120
Prestwick1_000120
Prestwick2_000120
Prestwick3_000120
Prestwick_438
Rodinolone
S1933_Selleck
SK-Triamcinolone
SMP1_000300
SMR000058333
SPBio_002079
Sk-Triamcinolone
T6376_SIGMA
TRIAMCINOLONE (SEE ALSO TRIAMCINOLONE ACETONIDE (76-25-5) AND TRIAMCINOLONE DIACETATE (67-78-7))
Tiamcinolonum
Tiamcinolonum [INN-Latin]
Tri-Nasal
Triacet
Triacort
Triam-Tablinen
Triamcet
Triamcinalone
Triamcinlon
Triamcinolon
Triamcinolona
Triamcinolona [INN-Spanish]
Triamcinolone (JP15/USP/INN)
Triamcinolone [USAN:INN:BAN:JAN]
Triamcinolone acetonide
Triamcinolone diacetate
Triamcinolone hexacetonide
Triamcinolonum
Triamcinolonum [INN]
Triatex
Tricortale
Triderm
Trilone
Tristoject
Trymex
UNII-1ZK20VI6TY
Vetalog
Volon
Volon A
WLN: L E5 B666 OV KU MUTJ A1 BF CQ E1 FV1Q FQ GQ
ZINC03882036
droxypregna-1,4-diene-3,20-dione
ione
nchembio.2007.53-comp7
triamcinolone
50
Heparinapproved, investigationalPhase 38129005-49-6772, 46507594
Synonyms:
101921-26-0
102-94-3
102785-31-9
104521-37-1
11078-24-3
11129-39-8
12656-11-0
2-o-sulfohexopyranuronosyl-(1->4)-2-deoxy-3-o-sulfo-2-(sulfoamino)hexopyranosyl-(1->4)-2-o-sulfohexopyranuronosyl-(1->4)-2-acetamido-2-deoxy-6-o-sulfohexopyranose
37324-73-5
6-[6-[6-[5-acetamido-4,6-dihydroxy-2-(sulfooxymethyl)oxan-3-yl]oxy-2-carboxy-4-hydroxy-5-sulfooxyoxan-3-yl]oxy-2-(hydroxymethyl)-5-(sulfoamino)-4-sulfooxyoxan-3-yl]oxy-3,4-dihydroxy-5-sulfooxyoxane-2-carboxylic acid
9041-08-1
9045-22-1
9075-96-1
913079-23-9
91449-79-5
AC1L19ZN
AC1L1ROY
ALFA 87-120
ALFA 87-163
ALFA 87-198
ALFA 87-81
ALFA 88-247
AR-1E4539
Allocinnamic acid
Ardeparin
Ardeparin sodium
Arteven
Bemiparin
Bemiparin sodium
CID772
CID8784
CY 216
Calciparine
Certoparin
Clexane
Clivarin
Clivarine
Cy 222
D006495
D017984
DB00407
DB01225
Dalteparin
Dalteparin sodium
Depo-Heparin
EINECS 232-681-7
EMT 966
EMT 967
EMT-966
EMT-967
EMT966
EMT967
Enoxaparin
Enoxaparin sodium
Enoxaparine
Eparina
Eparina [DCIT]
FR 860
Fluxum
Fragmin A
Fragmin B
Fragmin IV
Fraxiparin
H 2149
HSDB 3094
Hed-heparin
Hep Flush Kit in plastic container
Hep-Lock
Hep-Lock U/P
Hep-lock
Heparin
Heparin CY 216
Heparin Lock Flush
Heparin Lock Flush in plastic container
Heparin Lock Flush preservative free
Heparin Lock Flush preservative free in plastic container
Heparin Sodium
Heparin natrium
Heparin sodium
Heparin sodium 1,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 1,000 units in dextrose 5% in plastic container
Heparin sodium 1,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 10,000 units in dextrose 5%
Heparin sodium 10,000 units in dextrose 5% in plastic container
Heparin sodium 10,000 units in sodium chloride 0.45%
Heparin sodium 10,000 units in sodium chloride 0.9%
Heparin sodium 12,500 units in dextrose 5%
Heparin sodium 12,500 units in dextrose 5% in plastic container
Heparin sodium 12,500 units in sodium chloride 0.45% in plastic container
Heparin sodium 12,500 units in sodium chloride 0.9%
Heparin sodium 2,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 2,000 units in dextrose 5% in plastic container
Heparin sodium 2,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 20,000 units and dextrose 5% in plastic container
Heparin sodium 20,000 units in dextrose 5% in plastic container
Heparin sodium 25,000 units and dextrose 5% in plastic container
 
Heparin sodium 25,000 units in dextrose 5%
Heparin sodium 25,000 units in dextrose 5% in plastic container
Heparin sodium 25,000 units in sodium chloride 0.45% in plastic container
Heparin sodium 25,000 units in sodium chloride 0.9%
Heparin sodium 25,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 5,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 5,000 units in dextrose 5% in plastic container
Heparin sodium 5,000 units in sodium chloride 0.45%
Heparin sodium 5,000 units in sodium chloride 0.9%
Heparin sodium 5,000 units in sodium chloride 0.9% in plastic container
Heparin sodium in plastic container
Heparin sodium preservative Free
Heparin sulfate
Heparin sulphate
Heparin, Low Molecular Weight
Heparin, Low-Molecular-Weight
Heparin, sodium salt
Heparina
Heparina [INN-Spanish]
Heparinate
Heparine
Heparine [INN-French]
Heparinic acid
Heparinsodiumsalt
Heparinum
Heparinum [INN-Latin]
Heparinum natricum
Hepathrom
Hepflush-10
Inno-Hep
Innohep
Isocinnamic acid
KB 101
Kabi 2165
LHN 1
LMWH
Lioton 1000
Lipo-hepin
Liquaemin
Liquaemin Lock Flush
Liquaemin Sodium
Liquaemin sodium preservative free
Liquemin
Logiparin
Lovenox
Lovenox HP
Low Molecular Weight Heparin
Low molecular weight heparin
Low molecular weight heparin sodium
Low-Molecular-Weight Heparin
Minolteparin sodium
MolPort-003-760-257
Multiparin
NSC174025
Nadroparin
Nadroparine
Novoheparin
OP 386
OP 622
Octaparin
PK 10,169
PK-10,169
PK-10169
PK10,169
PK10169
Pabyrin
Panheprin
Parnaparin
Parnaparin sodium
Parvoparin
Pularin
Reviparin
Reviparin sodium
Ro 11
Sandoparin
Sodium acid heparin
Sodium heparin
Sodium heparinate
Subeparin
Sublingula
Thromboliquine
Tinzaparin
Tinzaparin sodium
Triofiban
UNII-12M44VTJ7B
UNII-3S182ET3UA
UNII-E47C0NF7LV
UNII-T2410KM04A
UNII-ZZ45AB24CA
Unfractionated heparin
Vetren
Vitrum AB
WY 90493RD
alpha-Heparin
cis-.beta.-Carboxystyrene
cis-Cinnamic acid
enoxaparin
heparin

Interventional clinical trials:

(show top 50)    (show all 108)
idNameStatusNCT IDPhase
1Bevacizumab and Peripheral Retinal Changes on Wide Field Angiography in Diabetic Macular EdemaUnknown statusNCT02096874Phase 4
2The DIOXXACT Trial(Diurnal IOP and OBF Xalatan vs Xalatan And Cosopt Trial)Unknown statusNCT00957190Phase 4
3The Prediction of Extent and Risk Profile of Coronary Atherosclerosis and Their Changes During Lipid-lowering Therapy Based on Non-invasive TechniquesUnknown statusNCT01773512Phase 4
4Widefield Angiography Guided Targeted-retinal Photocoagulation Combined With Anti VEgf Intravitreal Injections for the Treatment of Ischemic Central Retinal Vein Occlusion, Hemi Retinal Vein Occlusion, and Branch Retinal Vein OcclusionCompletedNCT01710839Phase 4
5Intravitreal Macugen for Ischaemic Diabetic Macular OedemaCompletedNCT01175070Phase 4
6Intraocular Bevacizumab (Avastin) for Rubeosis IridisCompletedNCT00557232Phase 4
7Neural Conduction Along the Visual Pathways After Oral Treatment With Citicoline in Patients With Optic Nerve DiseasesCompletedNCT00404729Phase 4
8ESPRIT: European/Australasian Stroke Prevention in Reversible Ischaemia TrialCompletedNCT00161070Phase 4
9Ophthalmic Findings During 10-year Enzyme Substitution of Danish Fabry Patients.CompletedNCT01997489Phase 4
10Laser Therapy Combined With Intravitreal Aflibercept vs Intravitreal Aflibercept Monotherapy (LADAMO)RecruitingNCT02432547Phase 4
11Evaluation of the Usefulness of a PRN Regimen Using Ranibizumab for Macular Edema Due to Branch Retinal Vein OcclusionRecruitingNCT02478515Phase 4
12Peripheral and Macular Retinal Vascular Perfusion and Leakage in DME and RVORecruitingNCT02503540Phase 4
13Aflibercept anD navigateD vErsus coNvensional Laser in Diabetic macUlar edeMaRecruitingNCT02554747Phase 4
14PDE5 Inhibitor Use and Non-arteritic Anterior Ischemic Optic Neuropathy (NAION)RecruitingNCT00867815Phase 4
15Long-Term Efficacy & Safety of Aflibercept IVT for the Treatment of DME in Subjects Who Completed the VISTA-DME TrialActive, not recruitingNCT02299336Phase 4
16Long-Term Efficacy and Safety of Intravitreal Aflibercept Injections for the Treatment of Diabetic Macular Edema in Subjects Who Completed the Three Year VISTA-DME Trial (The Endurance 2 Trial)Enrolling by invitationNCT02368756Phase 4
17Evaluation of the "Treat-and-extend" Scheme in Patients With Retinal Vein Occlusion (RVO) With and Without LASER Treatment of Ischaemic Retinal AreasNot yet recruitingNCT02522897Phase 4
18Ranibizumab and the Risk of Arterial Thromboembolic EventsTerminatedNCT01319188Phase 4
19Outcomes of Steroid and Oxygen Therapy Versus Placebo Therapy in Non-arteritic Anterior Ischemic Optic NeuropathyUnknown statusNCT02439866Phase 3
20Central Vein Occlusion Study (CVOS)CompletedNCT00000131Phase 3
21Long-term Treatment Effect of Intravitreal Ant-VEGF in Branch Retinal Vein OcclusionCompletedNCT02033031Phase 3
22Effect of Irbesartan on Endothelial Function of the Retinal Vasculature in Patients With HypercholesterolemiaCompletedNCT00152698Phase 3
23Combined Triple Procedure in Retinal Vein Occlusion (RVO)CompletedNCT00805064Phase 3
24Intravitreal Bevacizumab for Diabetic RetinopathyCompletedNCT00600262Phase 2, Phase 3
25Trial to Assess the Ocular Safety of Vorapaxar (SCH 530348) in Participants With Atherosclerosis (Study P05183)CompletedNCT00617123Phase 3
26Combined Triple Therapy in Diabetic Retinopathy (DRP)CompletedNCT00806169Phase 3
27Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke (POINT) TrialRecruitingNCT00991029Phase 3
28Phase 2/3, Randomized, Double-Masked, Sham-Controlled Trial of QPI-1007 in Subjects With Acute Nonarteritic Anterior Ischemic Optic Neuropathy (NAION)RecruitingNCT02341560Phase 2, Phase 3
29Erythropoietin in Methanol Associated Optic Neuropathy: A Phase-2 Clinical Trial (EPO-MAON Study)RecruitingNCT02376881Phase 3
30The Individually Marked Panretinal lasEr phoTokoagUlation for Proliferative Diabetic Retinopathy Study - DETECTActive, not recruitingNCT02157350Phase 3
31Trial of Aganirsen in iCRVO Patients at Risk of Developing NVGNot yet recruitingNCT02947867Phase 2, Phase 3
32A Study of the Beneficial Effects of Eplerenone on Central Serous ChorioretinopathyNot yet recruitingNCT02215330Phase 2, Phase 3
33Parnaparin vs Aspirin in the Treatment of Retinal Vein OcclusionTerminatedNCT00732927Phase 3
34Effect of Intravitreal Bone Marrow Stem Cells on Ischemic RetinopathyUnknown statusNCT01518842Phase 1, Phase 2
35Comparison of Two Laser Therapy Methods for PDRUnknown statusNCT01232179Phase 2
36Recombinant Erythropoietin for Neuroprotection in Very Preterm InfantsUnknown statusNCT00910234Phase 1, Phase 2
37Ranibizumab Supplementing Panretinal Photocoagulation as Treatment for Iris/Angle Neovascularization in Retinal Ischemic DiseaseCompletedNCT00841373Phase 1, Phase 2
38A Randomized, Double-Masked, Placebo-Controlled Two Cross Over Study Comparing the Effects of Moxaverine and Placebo on Ocular Blood FlowCompletedNCT00569621Phase 2
39Ranibizumab and Peripheral Scatter Laser in Patients With Diabetic Macular Edema and Peripheral NonperfusionCompletedNCT00815360Phase 2
40Effects of Moxaverine and Placebo on Ocular Blood FlowCompletedNCT00709423Phase 2
41Oral Propranolol Versus Placebo for Early Stages of Retinopathy of Prematurity: A Randomized and Prospective StudyCompletedNCT01238471Phase 1, Phase 2
42Study of the Efficacy and Tolerability of Intravitreal Injections of Ranibizumab Compared to Intravitreal Injections of Ranibizumab Combined With Targeted Retinal Photocoagulation to Treat Radiation Retinopathy.RecruitingNCT02222610Phase 2
43Prevention of Retinal Non-perfusion in Central Retinal Vein Occlusion by Hydroxycarbamide Treatment.RecruitingNCT02957760Phase 2
44Safety and Efficacy of Aflibercept in Proliferative Diabetic Retinopathy.RecruitingNCT02151695Phase 2
45Traumatic Optic Neuropathy Treatment Trial (TONTT)RecruitingNCT01783847Phase 1, Phase 2
46Hyperbaric Chamber for Central Retinal Vein Occlusion (CRVO) PatientsRecruitingNCT02405741Phase 2
47Fluoxetine for Visual Recovery After Ischemic StrokeRecruitingNCT02737930Phase 2
48Efficacy & Safety Trial of Intravitreal Injections Combined With PRP for CSME Secondary to Diabetes Mellitus (DAVE)Active, not recruitingNCT01552408Phase 1, Phase 2
49Intraocular Pressure During Prone Spinal SurgeryTerminatedNCT00176722Phase 2
50Lucentis for New Onset Neovascular GlaucomaWithdrawnNCT00727038Phase 1, Phase 2

Search NIH Clinical Center for Retinal Ischemia

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Retinal Ischemia cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Retinal Ischemia:
Bone marrow-derived stem cells for retinal diseases
Embryonic/Adult Cultured Cells Related to Retinal Ischemia:
Bone marrow-derived mononuclear cells (family), PMIDs: 23049424, 21225138, 19347139, 23000646

Genetic Tests for Retinal Ischemia

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Anatomical Context for Retinal Ischemia

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MalaCards organs/tissues related to Retinal Ischemia:

36
Eye, Bone, Endothelial, Retina, Bone marrow, Brain, Neutrophil

Publications for Retinal Ischemia

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Articles related to Retinal Ischemia:

(show top 50)    (show all 288)
idTitleAuthorsYear
1
Myeloid differentiation protein 2-dependent mechanisms in retinal ischemia-reperfusion injury. (28063877)
2017
2
Protective effect of etanercept, an inhibitor of tumor necrosis factor-I+, in a rat model of retinal ischemia. (27259948)
2016
3
A Mouse Model of Retinal Ischemia-Reperfusion Injury Through Elevation of Intraocular Pressure. (27501124)
2016
4
Cellular Stress Response and Immune Signaling in Retinal Ischemia-Reperfusion Injury. (27822213)
2016
5
Chi-Ju-Di-Huang-Wan protects rats against retinal ischemia by downregulating matrix metalloproteinase-9 and inhibiting p38 mitogen-activated protein kinase. (27617027)
2016
6
C1q propagates microglial activation and neurodegeneration in the visual axis following retinal ischemia/reperfusion injury. (27008854)
2016
7
Inhibiting Matrix Metalloproteinase 3 Ameliorates Neuronal Loss in the Ganglion Cell Layer of Rats in Retinal Ischemia/Reperfusion. (26830289)
2016
8
Lower Hemoglobin Concentration Is Associated with Retinal Ischemia and the Severity of Diabetic Retinopathy in Type 2 Diabetes. (27200379)
2016
9
Functional and Structural Evaluation of Sildenafil in a Rat Model of Acute Retinal Ischemia/Reperfusion Injury. (27421045)
2016
10
Peripheral retinal ischemia in a young Indian woman with neurofibromatosis type 1. (26949362)
2016
11
Calpain-1 and calpain-2 play opposite roles in retinal ganglion cell degeneration induced by retinal ischemia/reperfusion injury. (27185592)
2016
12
Hypoxic-Preconditioned Bone Marrow Stem Cell Medium Significantly Improves Outcome After Retinal Ischemia in Rats. (27367588)
2016
13
Astaxanthin Protects Against Retinal Damage: Evidence from In Vivo and In Vitro Retinal Ischemia and Reperfusion Models. (27158842)
2016
14
Methane attenuates retinal ischemia/reperfusion injury via anti-oxidative and anti-apoptotic pathways. (27208496)
2016
15
Refractory acute angle-closure glaucoma with retinal ischemia: January consultation #1. (26948794)
2016
16
Postconditioning with inhaled hydrogen promotes survival of retinal ganglion cells in a rat model of retinal ischemia/reperfusion injury. (26705611)
2016
17
Cryopreserved Mesenchymal Stromal Cells Maintain Potency in a Retinal Ischemia/Reperfusion Injury Model: Toward an off-the-shelf Therapy. (27212469)
2016
18
Pre-treatment with vinpocetine protects against retinal ischemia. (27899287)
2016
19
The protective effect of prophylactic ozone administration against retinal ischemia-reperfusion injury. (27028056)
2016
20
Cannabinoid receptors and TRPA1 on neuroprotection in a model of retinal ischemia. (27876485)
2016
21
Neuroprotective impact of prothymosin alpha-derived hexapeptide against retinal ischemia-reperfusion. (26779836)
2016
22
Utility of optical coherence tomography in the evaluation of monocular visual loss related to retinal ischemia. (26765759)
2016
23
Involvement of microRNA-181a and Bim in a rat model of retinal ischemia-reperfusion injury. (26949607)
2016
24
Effects of curcumin on interleukin-23 and interleukin-17 expression in rat retina after retinal ischemia-reperfusion injury. (26464670)
2015
25
Regulatory networks in retinal ischemia-reperfusion injury. (25902940)
2015
26
Structural and functional changes in retinal vasculature induced by retinal ischemia-reperfusion in rats. (25728136)
2015
27
Modeling transient retinal ischemia in mouse by ligation of pterygopalatine artery. (26526209)
2015
28
VINPOCETINE MODULATES METABOLIC ACTIVITY AND FUNCTION DURING RETINAL ISCHEMIA. (25696811)
2015
29
Comparison of pre-treatment and post-treatment use of selenium in retinal ischemia reperfusion injury. (25938038)
2015
30
Activation of autophagy and paraptosis in retinal ganglion cells after retinal ischemia and reperfusion injury in rats. (25574219)
2015
31
Chitosan oligosaccharides prevented retinal ischemia and reperfusion injury via reduced oxidative stress and inflammation in rats. (25479043)
2015
32
A novel imidazopyridine derivative, X22, prevents the retinal ischemia-reperfusion injury via inhibition of MAPKs. (25907396)
2015
33
Peripheral retinal ischemia following posttraumatic ocular hypertension in the setting of sickle cell trait. (25763551)
2015
34
Nerve growth factor protects retinal ganglion cells against injury induced by retinal ischemia-reperfusion in rats. (25707536)
2015
35
Neuroprotective effect of water-dispersible hesperetin in retinal ischemia reperfusion injury. (26407617)
2015
36
Peripheral Retinal Ischemia, Neovascularization, and Choroidal Infarction in Wyburn-Mason Syndrome. (25906291)
2015
37
Prediction of Retinal Ischemia in Branch Retinal Vein Occlusion: Spectral-Domain Optical Coherence Tomography Study. (26465891)
2015
38
Monomethyl fumarate promotes Nrf2-dependent neuroprotection in retinal ischemia-reperfusion. (26689280)
2015
39
Angiogenic and Inflammatory Vitreous Biomarkers Associated With Increasing Levels of Retinal Ischemia. (26447988)
2015
40
Hydrogen-rich saline reduces cell death through inhibition of DNA oxidative stress and overactivation of poly (ADP-ribose) polymerase-1 in retinal ischemia-reperfusion injury. (25954991)
2015
41
Intravitreal injection of lipoamino acid-modified connexin43 mimetic peptide enhances neuroprotection after retinal ischemia. (26238242)
2015
42
Upregulation of Homer1a Promoted Retinal Ganglion Cell Survival After Retinal Ischemia and Reperfusion via Interacting with Erk Pathway. (25924704)
2015
43
Diffuse retinal ischemia following intravenous crushed oxymorphone abuse. (24921173)
2014
44
The protective effects of dexmedetomidine against apoptosis in retinal ischemia/reperfusion injury in rats. (24517497)
2014
45
Effect of retinal ischemia on the non-image forming visual system. (25238585)
2014
46
Bilateral Exudative Retinal Detachment in a Diabetic Patient With Severe Peripheral Retinal Ischemia. (25256271)
2014
47
Identification of protein network alterations upon retinal ischemia-reperfusion injury by quantitative proteomics using a Rattus norvegicus model. (25549249)
2014
48
Peripheral retinal ischemia after intravenous tissue plasminogen activator for central retinal artery occlusion. (25284117)
2014
49
Protective effects of the neuropeptides PACAP, substance P and the somatostatin analogue octreotide in retinal ischemia: a metabolomic analysis. (24514073)
2014
50
Retinal ischemia/reperfusion injury is mediated by Toll-like receptor 4 activation of NLRP3 inflammasomes. (25097240)
2014

Variations for Retinal Ischemia

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Expression for genes affiliated with Retinal Ischemia

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Search GEO for disease gene expression data for Retinal Ischemia.

Pathways for genes affiliated with Retinal Ischemia

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Pathways related to Retinal Ischemia according to GeneCards Suite gene sharing:

(show all 48)
idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
10.0HIF1A, VEGFA
29.8BAX, CASP3
3
Show member pathways
9.6HIF1A, HSPB1, VEGFA
49.6CXCL12, HIF1A, VEGFA
59.5CXCL12, TNF, VEGFA
69.5BAX, CASP3, TNF
79.4CASP3, HIF1A, TNF, VEGFA
89.3NFKB1, TNF
99.3NFKB1, TNF
109.3BAX, CASP3, KNG1
11
Show member pathways
9.3BAX, CASP2, CASP3, HIF1A
12
Show member pathways
9.2BAX, CASP2, CASP3, TNF
139.1HIF1A, NFKB1, VEGFA
149.1CASP3, NFKB1, TNF
159.1CASP3, NFKB1, TNF
169.1CASP3, NFKB1, TNF
179.0CXCL12, NFKB1, TNF
188.9BAX, NFKB1, TNF
198.9BAX, NFKB1, TNF
20
Show member pathways
8.8BAX, CASP2, CASP3, HSPB1, TNF
218.8KNG1, NFKB1, TNF
22
Show member pathways
8.8CASP2, CASP3, NFKB1, TNF
238.7CASP3, HSPB1, NFKB1, TNF
24
Show member pathways
8.7HSPB1, NFKB1, TNF, VEGFA
258.7BAX, CASP3, NFKB1, VEGFA
26
Show member pathways
8.7CAT, NFKB1, SOD1
278.7CAT, NFKB1, SOD1
288.7BAX, CASP3, NFKB1, TNF
298.6CASP3, HIF1A, NFKB1, SOD1
30
Show member pathways
8.6BAX, CASP3, CXCL12, NFKB1
318.5CASP3, HIF1A, NFKB1, TNF, VEGFA
32
Show member pathways
8.5BAX, CASP3, CAT, SOD1, TNF
33
Show member pathways
8.5CASP2, CASP3, NFKB1, TNF, VEGFA
34
Show member pathways
8.5BAX, CASP3, HIF1A, NFKB1, VEGFA
358.4CASP2, CASP3, HSPB1, NFKB1, TNF
368.4BAX, CASP3, NFKB1, TNF, VEGFA
378.4BAX, CASP3, NFKB1, TNF, VEGFA
38
Show member pathways
8.4BAX, CASP2, CASP3, NFKB1, TNF
39
Show member pathways
8.4BAX, CASP3, NFKB1, PCNA
40
Show member pathways
8.4BAX, CASP2, CASP3, NFKB1, TNF
418.3BAX, NFKB1, PCNA, TNF
42
Show member pathways
8.3BAX, CAT, NFKB1, SOD1
43
Show member pathways
8.2CAT, HIF1A, NFKB1, SOD1, VEGFA
448.1BAX, CASP3, CXCL12, HIF1A, NFKB1, VEGFA
45
Show member pathways
8.0BAX, CASP3, NFKB1, PCNA, TNF
46
Show member pathways
8.0BAX, CASP2, CASP3, CXCL12, NFKB1, TNF
477.7BAX, CASP3, NFKB1, PCNA, TNF, VEGFA
48
Show member pathways
7.7BAX, CASP2, CASP3, CXCL12, NFKB1, TNF

GO Terms for genes affiliated with Retinal Ischemia

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Cellular components related to Retinal Ischemia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:00056157.7CAT, CXCL12, HSPB1, KNG1, SOD1, TNF

Biological processes related to Retinal Ischemia according to GeneCards Suite gene sharing:

(show top 50)    (show all 52)
idNameGO IDScoreTop Affiliating Genes
1camera-type eye morphogenesisGO:004859310.7HIF1A, VEGFA
2execution phase of apoptosisGO:009719410.7CASP2, CASP3
3positive regulation of neuroblast proliferationGO:000205210.7HIF1A, VEGFA
4positive regulation of transcription from RNA polymerase II promoter in response to hypoxiaGO:006141910.7HIF1A, VEGFA
5positive regulation of vascular endothelial growth factor receptor signaling pathwayGO:003094910.7HIF1A, VEGFA
6positive regulation of chemokine productionGO:003272210.6HIF1A, TNF
7cellular response to vascular endothelial growth factor stimulusGO:003592410.6HSPB1, VEGFA
8induction of positive chemotaxisGO:005093010.6CXCL12, VEGFA
9positive regulation of protein complex assemblyGO:003133410.6TNF, VEGFA
10activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome cGO:000863510.6BAX, CASP3
11positive regulation of blood vessel endothelial cell migrationGO:004353610.6HSPB1, VEGFA
12positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathwayGO:003803310.6HSPB1, VEGFA
13B cell homeostasisGO:000178210.6BAX, CASP3
14glial cell apoptotic processGO:003434910.6BAX, CASP3
15positive regulation of axon extension involved in axon guidanceGO:004884210.5CXCL12, VEGFA
16ectopic germ cell programmed cell deathGO:003523410.5BAX, CASP2
17regulation of I-kappaB kinase/NF-kappaB signalingGO:004312210.5HSPB1, TNF
18muscle cell cellular homeostasisGO:004671610.5HIF1A, SOD1
19negative regulation of apoptotic signaling pathwayGO:200123410.5BAX, HSPB1
20cellular response to organic cyclic compoundGO:007140710.4CASP3, HIF1A, TNF
21positive regulation of angiogenesisGO:004576610.3HIF1A, HSPB1, VEGFA
22response to glucocorticoidGO:005138410.3CASP3, HIF1A, TNF
23myeloid cell homeostasisGO:000226210.3BAX, SOD1
24positive regulation of endothelial cell proliferationGO:000193810.3CXCL12, HIF1A, VEGFA
25extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.3BAX, CASP2, CASP3
26positive regulation of cell adhesionGO:004578510.2CXCL12, TNF, VEGFA
27positive regulation of neuron apoptotic processGO:004352510.2BAX, CASP2, CASP3
28intrinsic apoptotic signaling pathway in response to DNA damageGO:000863010.2BAX, CASP2, TNF
29cellular response to nicotineGO:007131610.1NFKB1, TNF
30kidney developmentGO:000182210.1BAX, CAT, VEGFA
31response to salt stressGO:000965110.1BAX, HIF1A, TNF
32negative regulation of neuron apoptotic processGO:004352410.0BAX, HIF1A, SOD1
33ovarian follicle developmentGO:000154110.0BAX, SOD1, VEGFA
34response to organic substanceGO:001003310.0CASP3, SOD1, TNF
35response to X-rayGO:001016510.0CASP3, HIF1A
36activation of cysteine-type endopeptidase activity involved in apoptotic processGO:000691910.0BAX, CASP2, CASP3, TNF
37apoptotic signaling pathwayGO:00971909.9BAX, CASP2, CASP3, TNF
38DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrestGO:00069779.9BAX, CASP2, PCNA
39platelet degranulationGO:00025769.9KNG1, SOD1, VEGFA
40response to hydrogen peroxideGO:00425429.9CASP3, CAT, SOD1
41cellular response to mechanical stimulusGO:00712609.9CASP2, HIF1A, NFKB1
42cellular response to lipopolysaccharideGO:00712229.9HIF1A, NFKB1, TNF
43response to virusGO:00096159.8CXCL12, HSPB1, TNF
44positive regulation of NF-kappaB transcription factor activityGO:00510929.6CAT, NFKB1, TNF
45response to estradiolGO:00323559.6CASP3, CAT, HIF1A, PCNA
46agingGO:00075689.6BAX, CASP2, CAT, SOD1
47response to drugGO:00424939.5BAX, CASP3, CAT, SOD1
48response to hypoxiaGO:00016669.5CASP3, CAT, CXCL12, HIF1A, VEGFA
49response to copper ionGO:00466889.4BAX, NFKB1, SOD1
50positive regulation of apoptotic processGO:00430658.6BAX, CASP2, CASP3, HIF1A, KNG1, SOD1

Molecular functions related to Retinal Ischemia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cysteine-type endopeptidase activity involved in apoptotic processGO:009715310.6CASP2, CASP3
2enzyme bindingGO:00198999.1CASP2, CAT, HIF1A, PCNA, SOD1
3protein homodimerization activityGO:00428038.0BAX, CAT, NFKB1, SOD1, VEGFA
4identical protein bindingGO:00428027.8BAX, HSPB1, NFKB1, PCNA, SOD1, TNF

Sources for Retinal Ischemia

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet