MCID: RTN021
MIFTS: 47

Retinal Vascular Occlusion malady

Eye diseases, Cardiovascular diseases categories
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Summaries for Retinal Vascular Occlusion

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Wikipedia:65 Ocular ischemic syndrome is the constellation of ocular signs and symptoms secondary to severe, chronic... more...

MalaCards based summary: Retinal Vascular Occlusion, also known as unspecified retinal vascular occlusion, is related to retinal artery occlusion and retinal vein occlusion. An important gene associated with Retinal Vascular Occlusion is F5 (coagulation factor V (proaccelerin, labile factor)), and among its related pathways are Integrated Breast Cancer Pathway and Hemostasis. The compounds kaolin and coumarins have been mentioned in the context of this disorder. Affiliated tissues include eye, and related mouse phenotypes are integument and cardiovascular system.

Aliases & Classifications for Retinal Vascular Occlusion

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Sources:
8Disease Ontology, 44Novoseek, 62UMLS, 39NCIt, 57SNOMED-CT, 27ICD9CM, 25ICD10
See all sources

Retinal Vascular Occlusion, Aliases & Descriptions:

Name: Retinal Vascular Occlusion 8 44 62
Unspecified Retinal Vascular Occlusion 8 62
Retinal Vascular Occlusion, Unspecified 8
 
Retinal Vascular Occlusion Nos 8
Cardiovascular Occlusion 62
Retinal Vasc. Occlusion 8


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Eye diseases, Cardiovascular diseases


External Ids:

Disease Ontology8 DOID:1729
NCIt39 C34980
ICD9CM27 362.3, 362.30
ICD1025 H34

Related Diseases for Retinal Vascular Occlusion

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Diseases related to Retinal Vascular Occlusion via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 62)
idRelated DiseaseScoreTop Affiliating Genes
1retinal artery occlusion30.8APOH
2retinal vein occlusion30.7F5, APOH, VEGFA
3thrombophilia30.5APOH, SELP, F5
4central retinal vein occlusion30.3VEGFA, APOH, F5
5blindness30.3RHO, VEGFA
6antiphospholipid syndrome30.1APOH, SELP, F5
7retinitis11.1
8quebec platelet disorder10.5F5
9sneddon syndrome10.4APOH
10patent foramen ovale10.4F5
11thrombophlebitis10.4APOH
12endophthalmitis10.4VEGFA
13hepatic vein thrombosis10.4PIGA
14retinal disease10.3
15mondor disease10.3F5, APOH
16prothrombin deficiency10.3F5, APOH
17intracranial thrombosis10.3APOH, F5
18antithrombin iii deficiency10.3APOH, F5
19factor xii deficiency10.3F5, APOH
20protein s deficiency10.3F5, APOH
21severe pre-eclampsia10.3APOH, F5
22hellp syndrome10.2F5, APOH
23protein c deficiency10.2F5, APOH
24ovarian hyperstimulation syndrome10.2VEGFA, F5
25pulmonary embolism10.2APOH, F5
26pregnancy loss10.2APOH, F5
27behcet's disease10.2APOH, F5
28atherosclerosis10.1
29ischemic optic neuropathy10.1
30paroxysmal nocturnal hemoglobinuria10.1
31retinitis pigmentosa10.1
32hemoglobinuria10.1
33exfoliation syndrome10.1
34branch retinal artery occlusion10.1
35central retinal artery occlusion10.1
36thrombotic thrombocytopenic purpura10.1
37hemiplegia10.1
38neuropathy10.1
39papilledema10.1
40purpura10.1
41age related macular degeneration10.1VEGFA, RHO
42lupus erythematosus10.1APOH, F5
43von willebrand's disease10.1SELP, F5
44factor viii deficiency10.1F5, SELP
45hemolytic anemia10.1APOH, PIGA
46diabetic retinopathy10.1VEGFA, RHO
47thrombotic thrombocytopenic purpura, acquired10.0APOH, SELP
48adult respiratory distress syndrome10.0SELP, F5
49cerebrovascular disease10.0SELP, APOH
50proliferative diabetic retinopathy10.0VEGFA, SELP

Graphical network of the top 20 diseases related to Retinal Vascular Occlusion:



Diseases related to retinal vascular occlusion

Symptoms for Retinal Vascular Occlusion

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Drugs & Therapeutics for Retinal Vascular Occlusion

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Drug clinical trials:

Search ClinicalTrials for Retinal Vascular Occlusion

Search NIH Clinical Center for Retinal Vascular Occlusion

Genetic Tests for Retinal Vascular Occlusion

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Anatomical Context for Retinal Vascular Occlusion

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MalaCards organs/tissues related to Retinal Vascular Occlusion:

32
Eye

Animal Models for Retinal Vascular Occlusion or affiliated genes

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MGI Mouse Phenotypes related to Retinal Vascular Occlusion:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00107718.2F5, SELP, VEGFA, PIGA
2MP:00053858.1F5, RHO, SELP, VEGFA
3MP:00053868.1F5, SELP, VEGFA, PIGA
4MP:00053767.9VEGFA, APOH, SELP, RHO, F5
5MP:00036317.7F5, RHO, SELP, VEGFA, PIGA
6MP:00053977.7PIGA, VEGFA, SELP, RHO
7MP:00107687.6PIGA, VEGFA, APOH, SELP, F5

Publications for Retinal Vascular Occlusion

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Articles related to Retinal Vascular Occlusion:

(show top 50)    (show all 68)
idTitleAuthorsYear
1
Oral contraceptive pills: A risk factor for retinal vascular occlusion in in-vitro fertilization patients. (23869159)
2013
2
Pipeline embolization device: a new source for embolic retinal vascular occlusion. (24051422)
2013
3
Impact of cilostazol on the progression of carotid atherosclerosis in patients with retinal vascular occlusion. (24034133)
2013
4
Thrombophilia and retinal vascular occlusion. (22969282)
2012
5
Central retinal vascular occlusion associated with acute retinal necrosis. (22491922)
2012
6
Retinal vascular occlusion after vitrectomy with retrobulbar anesthesia-observational case series and survey of literature. (21850439)
2011
7
Retinal vascular occlusion during in vitro fertilization. (25390129)
2010
8
Factor V Leiden mutation with retinal vascular occlusion. (21199226)
2010
9
Retinal vascular occlusion syndromes. (19584622)
2009
10
Retinal vascular occlusions: an interdisciplinary challenge. (19626196)
2008
11
Low density lipoprotein triglycerides and lipoprotein(a) are risk factors for retinal vascular occlusion. (17481600)
2007
12
Role of hyperhomocystinemia in retinal vascular occlusive disease. (17164500)
2007
13
Retinal vascular occlusion following ocular contusion. (15931542)
2005
14
Retinal vascular occlusion following traumatic hyphema and glaucoma, as a presenting sign of sickle cell trait. (16011069)
2005
15
Retinal vascular occlusion in patients infected with human immunodeficiency virus. (16141865)
2005
16
Impairment of homocysteine metabolism in patients with retinal vascular occlusion and non-arteritic ischemic optic neuropathy. (16197292)
2005
17
Central retinal vascular occlusion by orbital pseudotumor. (15187672)
2004
18
Hyperhomocysteinaemia: risk of retinal vascular occlusion. (16335656)
2004
19
Meta-analysis of plasma homocysteine, serum folate, serum vitamin B(12), and thermolabile MTHFR genotype as risk factors for retinal vascular occlusive disease. (14644226)
2003
20
Factor V Leiden mutation does not correlate with retinal vascular occlusion in white patients with BehAset's disease. (12881356)
2003
21
Unilateral peripheral retinal vascular occlusion in a young Japanese woman with neurofibromatosis-1. (12972769)
2003
22
Retinal vascular occlusion and primary antiphospholipid syndrome. Report of 2 cases]. (11912840)
2001
23
The electroretinogram in patients with retinal vascular occlusion. (12567597)
2001
24
Systemic disorders associated with retinal vascular occlusion. (11141642)
2000
25
Retinal vascular occlusion and deficiencies in the protein C pathway. (10653431)
2000
26
Retinal vascular occlusion and deficiencies in the protein C pathway. (10653432)
2000
27
Retinal vascular occlusion and deficiencies in the protein C pathway. (10482096)
1999
28
Genetic thrombophilia in patients with retinal vascular occlusion. (11456253)
1999
29
Abnormalities in haemorheological factors and lipoprotein (a) in retinal vascular occlusion: implications for increased vascular risk. (9683948)
1998
30
Visual field loss caused by retinal vascular occlusion after vitrectomy surgery. (9152086)
1997
31
Cocaine-associated retinal vascular occlusion: report of two cases. (8059789)
1994
32
Lipoprotein (a): a risk factor for retinal vascular occlusion. (1477637)
1992
33
The investigation of patients with retinal vascular occlusion. (2209910)
1990
34
Massive bilateral retinal vascular occlusion. (2475899)
1989
35
Retinal vascular occlusion without retrobulbar or optic nerve sheath hemorrhage after retrobulbar injection of lidocaine. (3231409)
1988
36
Experimental retinal vascular occlusion. II. A clinico-pathologic correlative study of simultaneous occlusion of central retinal vein and artery. (3721721)
1986
37
Ocular neovascularization with retinal vascular occlusion-III. Incidence of ocular neovascularization with retinal vein occlusion. (6192376)
1983
38
Ocular neovascularization with retinal vascular occlusion. I. Association with experimental retinal vein occlusion. (6175297)
1982
39
Ocular neovascularization with retinal vascular occlusion. II. Occurrence in central and branch retinal artery occlusion. (6182865)
1982
40
Experimental retinal vascular occlusion. I. Pathogenesis of central retinal vein occlusion. (415709)
1978
41
Acute infantile hemiplegia associated with ipsilateral retinal vascular occlusion. (4843527)
1974
42
Sudden blindness after ventriculography. Bilateral retinal vascular occlusion superimposed on papilledema. (4546564)
1974
43
Abnormal glucose tolerance in association with retinal vascular occlusion. (4752297)
1973
44
Retinal vascular occlusion in the cat by photocoagulation: trial of a new instrument. (4753336)
1973
45
Fluorescein studies in retinal vascular occlusion. (5635899)
1968
46
Microangiography in retinal vascular occlusion [abstract]. (20919019)
1968
47
CURRENT DEVELOPMENTS IN OPHTHALMOLOGY. FIBRINOLYSIS IN RETINAL VASCULAR OCCLUSION. (14190868)
1964
48
INTRAVENOUS STREPTOKINASE IN THE TREATMENT OF RETINAL VASCULAR OCCLUSION. (14159485)
1964
49
Retinal vascular occlusion associated with gastro-intestinal hemorrhage. (13977191)
1962
50
Anticoagulant therapy in retinal vascular occlusion. (18136778)
1949

Variations for Retinal Vascular Occlusion

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Expression for genes affiliated with Retinal Vascular Occlusion

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Expression patterns in normal tissues for genes affiliated with Retinal Vascular Occlusion

Search GEO for disease gene expression data for Retinal Vascular Occlusion.

Pathways for genes affiliated with Retinal Vascular Occlusion

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Pathways related to Retinal Vascular Occlusion according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.4RHO, VEGFA
2
Show member pathways
8.7F5, SELP, VEGFA
3
Show member pathways
8.7F5, SELP, VEGFA

Compounds for genes affiliated with Retinal Vascular Occlusion

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Compounds related to Retinal Vascular Occlusion according to GeneCards/GeneDecks:

(show top 50)    (show all 70)
idCompoundScoreTop Affiliating Genes
1kaolin4410.0APOH, F5
2coumarins4410.0F5, APOH
3cardiolipin44 1110.9F5, APOH
4phosphatidylethanolamine44 1110.8F5, APOH
5fluorescein44 1110.8VEGFA, F5
6batroxobin449.7F5, SELP
7tyrosine sulfate449.7F5, SELP
8bivalirudin44 1110.7F5, SELP
9argatroban44 1110.6SELP, F5
10penicillin449.6F5, SELP
1111-dehydrothromboxane b2449.6APOH, SELP
12ristocetin449.6SELP, F5
13ticlopidine44 1110.5SELP, APOH
14desmopressin44 61 28 1112.5SELP, F5
15ptca449.5SELP, APOH
16deoxyribonucleic acid449.5F5, APOH
17fluorochrome449.5SELP, RHO
18hirudin449.5SELP, F5
19quinacrine44 1110.5SELP, APOH
20phosphatidylcholine449.5APOH, RHO, F5
21candesartan44 50 28 1112.4SELP, VEGFA
22phospholipid449.4APOH, RHO, F5
23protamine449.4SELP, F5
24txb2449.4APOH, SELP
25mycophenolate mofetil44 50 1111.4SELP, F5
26dermatan sulfate449.3F5, SELP
27dextran sulfate449.2F5, SELP, APOH
28warfarin44 50 24 1112.2F5, APOH, SELP
29kininogen449.2F5, APOH, SELP
30homocysteine44 2410.2APOH, SELP, F5
31cocaine44 1110.2SELP, APOH, F5
32infliximab44 50 1111.2APOH, VEGFA
33aspirin44 50 28 2412.2APOH, SELP, F5
34halothane44 50 28 1112.2RHO, SELP, F5
35atorvastatin44 50 28 24 1113.1SELP, F5, VEGFA
36simvastatin44 50 61 28 24 1114.1VEGFA, F5, SELP
37fibrinogen449.1F5, SELP, APOH
38epinephrine44 24 1111.1SELP, RHO, F5
39polysaccharide449.1SELP, RHO, F5
40lactate449.0SELP, APOH, F5
41ly294002448.9RHO, VEGFA, SELP
42cyclophosphamide44 50 1110.9VEGFA, APOH, PIGA, F5
43creatinine448.8F5, APOH, SELP
44aspartate448.7RHO, SELP, F5
45phosphatidylserine44 28 1110.7F5, RHO, SELP, APOH
46arginine448.7RHO, APOH, F5, SELP
47estrogen448.6SELP, VEGFA, F5, APOH
48prostacyclin448.2RHO, F5, SELP, APOH, VEGFA
49heparin44 28 24 1111.2F5, VEGFA, APOH, SELP, RHO
50vegf448.2F5, VEGFA, APOH, SELP, RHO

GO Terms for genes affiliated with Retinal Vascular Occlusion

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Cellular components related to Retinal Vascular Occlusion according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1platelet alpha granule lumenGO:0310939.5F5, VEGFA
2extracellular spaceGO:0056158.0F5, SELP, APOH, VEGFA

Biological processes related to Retinal Vascular Occlusion according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of leukocyte migrationGO:0026879.0SELP, VEGFA
2platelet degranulationGO:0025768.7F5, SELP, VEGFA
3blood coagulationGO:0075968.7F5, SELP, VEGFA
4platelet activationGO:0301688.4VEGFA, SELP, F5

Molecular functions related to Retinal Vascular Occlusion according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1glycoprotein bindingGO:0019489.2SELP, APOH
2heparin bindingGO:0082018.6SELP, APOH, VEGFA
3protein bindingGO:0055156.8PIGA, VEGFA, APOH, SELP, RHO, F5

Products for genes affiliated with Retinal Vascular Occlusion

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  • Antibodies
  • Proteins
  • Lysates

Sources for Retinal Vascular Occlusion

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet