MCID: RTN021
MIFTS: 32

Retinal Vascular Occlusion malady

Categories: Eye diseases, Cardiovascular diseases

Aliases & Classifications for Retinal Vascular Occlusion

Aliases & Descriptions for Retinal Vascular Occlusion:

Name: Retinal Vascular Occlusion 12 52 14 69
Retinal Vascular Occlusion, Unspecified 12
Unspecified Retinal Vascular Occlusion 12
Retinal Vascular Occlusion Nos 12
Retinal Vasc. Occlusion 12

Classifications:



External Ids:

Disease Ontology 12 DOID:1729
ICD10 33 H34 H34.9
ICD9CM 35 362.3 362.30
NCIt 47 C34980
UMLS 69 C0035326

Summaries for Retinal Vascular Occlusion

MalaCards based summary : Retinal Vascular Occlusion, also known as retinal vascular occlusion, unspecified, is related to central retinal vein occlusion and retinitis, and has symptoms including amaurosis fugax An important gene associated with Retinal Vascular Occlusion is APOH (Apolipoprotein H). The drugs Bevacizumab and Triamcinolone have been mentioned in the context of this disorder. Affiliated tissues include eye.

Related Diseases for Retinal Vascular Occlusion

Diseases related to Retinal Vascular Occlusion via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 25)
id Related Disease Score Top Affiliating Genes
1 central retinal vein occlusion 10.7
2 retinitis 10.6
3 central retinal artery occlusion 10.3
4 transient retinal arterial occlusion 10.1
5 thrombophilia 9.9
6 retinal vein occlusion 9.9
7 antiphospholipid syndrome 9.8
8 atherosclerosis 9.6
9 hemoglobinuria 9.6
10 ischemic optic neuropathy 9.6
11 paroxysmal nocturnal hemoglobinuria 9.6
12 retinal artery occlusion 9.6
13 vasculitis 9.6
14 retinitis pigmentosa 9.6
15 chickenpox 9.6
16 thrombotic thrombocytopenic purpura 9.6
17 neuropathy 9.6
18 hemiplegia 9.6
19 lupus erythematosus 9.6
20 retinal vasculitis 9.6
21 branch retinal artery occlusion 9.6
22 papilledema 9.6
23 systemic lupus erythematosus 9.6
24 purpura 9.6
25 exfoliation syndrome 9.6

Comorbidity relations with Retinal Vascular Occlusion via Phenotypic Disease Network (PDN):


Hypertension, Essential Ischemic Heart Disease

Graphical network of the top 20 diseases related to Retinal Vascular Occlusion:



Diseases related to Retinal Vascular Occlusion

Symptoms & Phenotypes for Retinal Vascular Occlusion

UMLS symptoms related to Retinal Vascular Occlusion:


amaurosis fugax

Drugs & Therapeutics for Retinal Vascular Occlusion

Drugs for Retinal Vascular Occlusion (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 165)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Bevacizumab Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 216974-75-3
2
Triamcinolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 124-94-7 31307
3
Ranibizumab Approved Phase 4,Phase 3,Phase 2,Phase 1 347396-82-1 459903
4
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 50-02-2 5743
5
Aspirin Approved, Vet_approved Phase 4,Phase 3 50-78-2 2244
6
Dipyridamole Approved Phase 4 58-32-2 3108
7
Verteporfin Approved, Investigational Phase 4 129497-78-5
8
Glucosamine Approved, Nutraceutical Phase 4 3416-24-8 439213
9 Endothelial Growth Factors Phase 4,Phase 3,Phase 1,Phase 2
10 Mitogens Phase 4,Phase 3,Phase 1,Phase 2
11 Angiogenesis Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
12 Angiogenesis Modulating Agents Phase 4,Phase 3,Phase 2,Phase 1
13 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
14 glucocorticoids Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
15 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
16 Hormones Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
17 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
18 Immunosuppressive Agents Phase 4,Phase 3,Phase 2,Phase 1
19 triamcinolone acetonide Phase 4,Phase 3,Phase 2,Phase 1
20 Triamcinolone diacetate Phase 4,Phase 3,Phase 2,Phase 1
21 Triamcinolone hexacetonide Phase 4,Phase 3,Phase 2,Phase 1
22 Anticholesteremic Agents Phase 4,Phase 3
23 Antimetabolites Phase 4,Phase 3,Phase 2
24 Calcium, Dietary Phase 4,Phase 3
25 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 4,Phase 3
26 Hypolipidemic Agents Phase 4,Phase 3,Phase 2
27 Lipid Regulating Agents Phase 4,Phase 3,Phase 2
28 Rosuvastatin Calcium Phase 4 147098-20-2
29 Antiemetics Phase 4,Phase 2,Phase 3,Phase 1
30 Antineoplastic Agents, Hormonal Phase 4,Phase 2,Phase 3,Phase 1
31 Autonomic Agents Phase 4,Phase 2,Phase 3,Phase 1
32 BB 1101 Phase 4,Phase 2,Phase 3,Phase 1
33 Dexamethasone 21-phosphate Phase 4,Phase 2,Phase 3,Phase 1
34 Dexamethasone acetate Phase 4,Phase 2,Phase 3,Phase 1 1177-87-3
35 Gastrointestinal Agents Phase 4,Phase 2,Phase 3,Phase 1
36 HIV Protease Inhibitors Phase 4,Phase 2,Phase 3,Phase 1
37 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 3,Phase 1
38
protease inhibitors Phase 4,Phase 2,Phase 3,Phase 1
39 Fibrinolytic Agents Phase 4,Phase 3,Phase 1
40
Lactitol Phase 4 585-86-4 3871
41 Pharmaceutical Solutions Phase 4,Phase 2,Phase 3,Phase 1
42 Mitomycins Phase 4
43 Analgesics Phase 4,Phase 3
44 Analgesics, Non-Narcotic Phase 4,Phase 3
45 Anti-Inflammatory Agents, Non-Steroidal Phase 4,Phase 3
46 Antipyretics Phase 4,Phase 3
47 Antirheumatic Agents Phase 4,Phase 3,Phase 1,Phase 2
48 Cyclooxygenase Inhibitors Phase 4,Phase 3
49 Phosphodiesterase Inhibitors Phase 4,Phase 2
50 Platelet Aggregation Inhibitors Phase 4,Phase 3

Interventional clinical trials:

(show top 50) (show all 253)
id Name Status NCT ID Phase
1 Study of Intravitreal Aflibercept Injection for Persistent CRVO-associated Macular Edema Despite Prior Anti-VEGF Therapy Unknown status NCT01857544 Phase 4
2 Study to Evaluate Efficacy of Aflibercept in Neovascular Age-related Macular Degeneration Patients Non Responders to Anti-Vascular Endothelial Growth Factor Unknown status NCT01896284 Phase 4
3 Treatment of Bevacizumab and Triamcinolone in Treatment or Macular Edema Secondary to CRVO Unknown status NCT00566761 Phase 4
4 The Prediction of Extent and Risk Profile of Coronary Atherosclerosis and Their Changes During Lipid-lowering Therapy Based on Non-invasive Techniques Unknown status NCT01773512 Phase 4
5 Ranibizumab in Patients With Branch Retinal Vein Occlusion Completed NCT01027481 Phase 4
6 Morphological and Functional Retinal Changes Following Retinal Photocoagulation Completed NCT00682240 Phase 4
7 Evaluation of Macugen Treatment of Macular Edema Due to Branch Retinal Vein Occlusion Completed NCT00406107 Phase 4
8 Efficacy and Safety of Lucentis® (Ranibizumab Intravitreal Injections) in Chilean Patients With Diabetic Macular Edema. Completed NCT02140411 Phase 4
9 Widefield Angiography Guided Targeted-retinal Photocoagulation Combined With Anti VEgf Intravitreal Injections for the Treatment of Ischemic Central Retinal Vein Occlusion, Hemi Retinal Vein Occlusion, and Branch Retinal Vein Occlusion Completed NCT01710839 Phase 4
10 NEWTON: Aflibercept Injection for Previously Treated Macular Edema Associated With Central Retinal Vein Occlusions Completed NCT01870427 Phase 4
11 Hemodilution Versus Ranibizumab in Early-onset Central Retinal Vein Occlusion Completed NCT01448018 Phase 4
12 Single Site, Masked, Randomized, Controlled Study to Assess Efficacy of Osurdex as Adjunct to Avastin Compared With Avastin Alone in the Treatment of Patients With Macular Edema Due to Central or Branch Retinal Vein Occlusion Completed NCT01085734 Phase 4
13 Safety and Efficacy Study of Ozurdex® Compared to Lucentis® in Patients With Branch Retinal Vein Occlusion Completed NCT01427751 Phase 4
14 A Safety and Efficacy Study of OZURDEX® in Macular Edema Associated With Branch Retinal Vein Occlusion Completed NCT01903720 Phase 4
15 A Study Evaluating Dosing Regimens for Treatment With Intravitreal Ranibizumab Injections in Subjects With Macular Edema Following Retinal Vein Occlusion Completed NCT01277302 Phase 4
16 Extension Study to Compare Long-term Efficacy and Safety of Ranibizumab Intravitreal Injections Versus Dexamethasone Intravitreal Implant in Patients With RVO Completed NCT01580020 Phase 4
17 Dexamethasone-implant for the Treatment of RVO Completed NCT01767545 Phase 4
18 Intravitreal Macugen for Ischaemic Diabetic Macular Oedema Completed NCT01175070 Phase 4
19 Intravitreous Ranibizumab as Adjunctive Treatment for Trabeculectomy in Neovascular Glaucoma Completed NCT01922154 Phase 4
20 ESPRIT: European/Australasian Stroke Prevention in Reversible Ischaemia Trial Completed NCT00161070 Phase 4
21 Comparison of Retinal Oxygenation and Retinal Vessel Diameters in Healthy Subjects and Patients With Diabetic Retinopathy or Retinal Vein Occlusion Between DVA and Oxymap Recruiting NCT02521116 Phase 4
22 Ozurdex Versus Ranibizumab Versus Combination for Central Retinal Vein Occlusion Recruiting NCT01827722 Phase 4
23 Retinal Sensitivity in BRVO After Anti-VEGF Therapy Recruiting NCT02527733 Phase 4
24 Study to Show a Superior Benefit in Terms of Reduction of Ranibizumab Injections in Patients Receiving Ranibizumab Plus Laser Photocoagulation Combination Therapy Without Loss of Efficacy and Safety Recruiting NCT02953938 Phase 4
25 Evaluation of a Treat and Extend Regimen of Intravitreal Aflibercept for Macular Edema Secondary to CRVO Recruiting NCT02800642 Phase 4
26 Evaluation of the Usefulness of a PRN Regimen Using Ranibizumab for Macular Edema Due to Branch Retinal Vein Occlusion Recruiting NCT02478515 Phase 4
27 Safety and Efficacy of Switching From Aflibercept to Ranibizumab in Patients With nAMD Recruiting NCT02161575 Phase 4
28 Cohort Study of the Clinical Course of Macular Diseases in Kagawa Recruiting NCT02321267 Phase 4
29 Continuation of Previous Study to Gather More Data on Effect of Macugen on the Corneal Endothelium Recruiting NCT01573572 Phase 4
30 Peripheral and Macular Retinal Vascular Perfusion and Leakage in DME and RVO Active, not recruiting NCT02503540 Phase 4
31 Ranibizumab for Macular Edema Secondary to Branch Retinal Vein Occlusion in Patients With Fair Vision Active, not recruiting NCT01795209 Phase 4
32 Comparing Injection Frequency Between Aflibercept and Ranibizumab in Patients With CRVO With a Treat& Extend Regimen Active, not recruiting NCT02274259 Phase 4
33 Evaluation of the "Treat-and-extend" Scheme in Patients With Retinal Vein Occlusion (RVO) With and Without LASER Treatment of Ischaemic Retinal Areas Not yet recruiting NCT02522897 Phase 4
34 Strategies for Management of Corneal Neovascularisation Not yet recruiting NCT02594423 Phase 4
35 Cytokine and Visual Outcome Variations in Eyes Receiving Aflibercept Not yet recruiting NCT03056079 Phase 4
36 Cytokine and Visual Outcome Variations in Eyes Receiving Ranibizumab Not yet recruiting NCT03056092 Phase 4
37 TF (SENSIMED Triggerfish) in Intraocular Anti-VEGF (Vascular Endothelial Growth Factor) Injection Terminated NCT01983579 Phase 4
38 Ranibizumab and the Risk of Arterial Thromboembolic Events Terminated NCT01319188 Phase 4
39 Bevacizumab and Retinal Vascular Occlusions Unknown status NCT00347711 Phase 3
40 Atorvastatin for the Treatment of Retinal Vein Occlusion Unknown status NCT00517257 Phase 3
41 Comparison of Intravitreal Ranibizumab and Macular Laser Photocoagulation for ME Following Branch Retinal Vein Occlusion (BRVO) Unknown status NCT01189526 Phase 3
42 Comparing the Effectiveness and Costs of Bevacizumab to Ranibizumab in Patients With Retinal Vein Occlusions (BRVO) Unknown status NCT01635803 Phase 2, Phase 3
43 TTT Versus PDT for Treatment of Choroidal Neovascularization in Age-Related Macular Degeneration Unknown status NCT00260403 Phase 2, Phase 3
44 Effect of Avastin in Juxtafoveal Telangiectasias Unknown status NCT00406380 Phase 3
45 Long-term Treatment Effect of Intravitreal Ant-VEGF in Branch Retinal Vein Occlusion Completed NCT02033031 Phase 3
46 Vascular Endothelial Growth Factor (VEGF) Trap-Eye: Investigation of Efficacy and Safety in Central Retinal Vein Occlusion (CRVO) Completed NCT00943072 Phase 3
47 Vascular Endothelial Growth Factor (VEGF) Trap-Eye: Investigation of Efficacy and Safety in Central Retinal Vein Occlusion (CRVO) Completed NCT01012973 Phase 3
48 Steroid Injections vs. Standard Treatment for Macular Edema Due to Retinal Blood Vessel Blockage Completed NCT00106132 Phase 3
49 Intravitreal Bevacizumab and Triamcinolone Associated to Laser Photocoagulation for Diabetic Macular Edema(IBeTA) Completed NCT00997191 Phase 3
50 Retrospective Study of the Effectiveness and Safety of Niacin and Steroid Eye Drops for Retinal Vein Occlusions Completed NCT00500045 Phase 2, Phase 3

Search NIH Clinical Center for Retinal Vascular Occlusion

Genetic Tests for Retinal Vascular Occlusion

Anatomical Context for Retinal Vascular Occlusion

MalaCards organs/tissues related to Retinal Vascular Occlusion:

39
Eye

Publications for Retinal Vascular Occlusion

Articles related to Retinal Vascular Occlusion:

(show top 50) (show all 75)
id Title Authors Year
1
Risk of Mortality and of Atherosclerotic Events Among Patients Who Underwent Hemodialysis and Subsequently Developed Retinal Vascular Occlusion: A Taiwanese Retrospective Cohort Study. ( 26720586 )
2016
2
ADULT WITH CHICKENPOX COMPLICATED BY SYSTEMIC VASCULITIS AND BILATERAL RETINAL VASCULITIS WITH RETINAL VASCULAR OCCLUSIONS. ( 27533640 )
2016
3
Venous thromboembolism does not share familial susceptibility with retinal vascular occlusion or glaucoma: a nationwide family study. ( 27283943 )
2016
4
Retinal vascular occlusion: a window to diagnosis of familial and acquired thrombophilia and hypofibrinolysis, with important ramifications for pregnancy outcomes. ( 27563233 )
2016
5
SEVERE BILATERAL RETINAL VASCULAR OCCLUSION AS FIRST PRESENTATION OF SYSTEMIC LUPUS ERYTHEMATOSUS AND ANTIPHOSPHOLIPID SYNDROME. ( 27548039 )
2016
6
Impact of cilostazol on the progression of carotid atherosclerosis in patients with retinal vascular occlusion. ( 24034133 )
2013
7
Pipeline embolization device: a new source for embolic retinal vascular occlusion. ( 24051422 )
2013
8
Oral contraceptive pills: A risk factor for retinal vascular occlusion in in-vitro fertilization patients. ( 23869159 )
2013
9
Thrombophilia and retinal vascular occlusion. ( 22969282 )
2012
10
Central retinal vascular occlusion associated with acute retinal necrosis. ( 22491922 )
2012
11
Retinal vascular occlusion after vitrectomy with retrobulbar anesthesia-observational case series and survey of literature. ( 21850439 )
2011
12
Retinal vascular occlusion during in vitro fertilization. ( 25390129 )
2010
13
Factor V Leiden mutation with retinal vascular occlusion. ( 21199226 )
2010
14
Retinal vascular occlusions occur more frequently in the more affected eye in exfoliation syndrome. ( 19557023 )
2010
15
Retinal vascular occlusion syndromes. ( 19584622 )
2009
16
Paroxysmal nocturnal hemoglobinuria may cause retinal vascular occlusions. ( 18437293 )
2009
17
Retinal vascular occlusions: an interdisciplinary challenge. ( 19626196 )
2008
18
Low density lipoprotein triglycerides and lipoprotein(a) are risk factors for retinal vascular occlusion. ( 17481600 )
2007
19
Role of hyperhomocystinemia in retinal vascular occlusive disease. ( 17164500 )
2007
20
Inappropriate investigation and management of a retinal vascular occlusion. ( 16082396 )
2006
21
Retinal vascular occlusion following ocular contusion. ( 15931542 )
2005
22
Impairment of homocysteine metabolism in patients with retinal vascular occlusion and non-arteritic ischemic optic neuropathy. ( 16197292 )
2005
23
Retinal vascular occlusion following traumatic hyphema and glaucoma, as a presenting sign of sickle cell trait. ( 16011069 )
2005
24
Retinal vascular occlusion in patients infected with human immunodeficiency virus. ( 16141865 )
2005
25
Retinal vascular occlusion with overlying vitreous hemorrhage masquerading as a tumor. ( 15710833 )
2005
26
[The characteristics of retinitis pigmentosa with retinal vascular occlusion]. ( 15938805 )
2005
27
Central retinal vascular occlusion by orbital pseudotumor. ( 15187672 )
2004
28
Hyperhomocysteinaemia: risk of retinal vascular occlusion. ( 16335656 )
2004
29
Meta-analysis of plasma homocysteine, serum folate, serum vitamin B(12), and thermolabile MTHFR genotype as risk factors for retinal vascular occlusive disease. ( 14644226 )
2003
30
Factor V Leiden mutation does not correlate with retinal vascular occlusion in white patients with BehAset's disease. ( 12881356 )
2003
31
Unilateral peripheral retinal vascular occlusion in a young Japanese woman with neurofibromatosis-1. ( 12972769 )
2003
32
[Thrombophilia factors as inducers of retinal vascular occlusion]. ( 11450475 )
2001
33
[Retinal vascular occlusion and primary antiphospholipid syndrome. Report of 2 cases]. ( 11912840 )
2001
34
The electroretinogram in patients with retinal vascular occlusion. ( 12567597 )
2001
35
Thermolabile MTHFR genotype and retinal vascular occlusive disease. ( 11133719 )
2001
36
Retinal vascular occlusion and deficiencies in the protein C pathway. ( 10653432 )
2000
37
Systemic disorders associated with retinal vascular occlusion. ( 11141642 )
2000
38
Retinal vascular occlusion and deficiencies in the protein C pathway. ( 10653431 )
2000
39
Retinal vascular occlusion and deficiencies in the protein C pathway. ( 10482096 )
1999
40
Genetic thrombophilia in patients with retinal vascular occlusion. ( 11456253 )
1999
41
Abnormalities in haemorheological factors and lipoprotein (a) in retinal vascular occlusion: implications for increased vascular risk. ( 9683948 )
1998
42
Visual field loss caused by retinal vascular occlusion after vitrectomy surgery. ( 9152086 )
1997
43
Peripheral retinal neovascularization and retinal vascular occlusion associated with activated protein C resistance. ( 9372725 )
1997
44
Antiphospholipid antibodies in retinal vascular occlusions. A prospective study of 75 patients. ( 8002838 )
1994
45
Cocaine-associated retinal vascular occlusion: report of two cases. ( 8059789 )
1994
46
Lipoprotein (a): a risk factor for retinal vascular occlusion. ( 1477637 )
1992
47
The investigation of patients with retinal vascular occlusion. ( 2209910 )
1990
48
Massive bilateral retinal vascular occlusion. ( 2475899 )
1989
49
Massive bilateral retinal vascular occlusion secondary to thrombotic thrombocytopenic purpura. ( 2976518 )
1988
50
Retinal vascular occlusion without retrobulbar or optic nerve sheath hemorrhage after retrobulbar injection of lidocaine. ( 3231409 )
1988

Variations for Retinal Vascular Occlusion

Expression for Retinal Vascular Occlusion

Search GEO for disease gene expression data for Retinal Vascular Occlusion.

Pathways for Retinal Vascular Occlusion

GO Terms for Retinal Vascular Occlusion

Sources for Retinal Vascular Occlusion

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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