MCID: RTN021
MIFTS: 39

Retinal Vascular Occlusion malady

Eye diseases, Cardiovascular diseases categories

Summaries for Retinal Vascular Occlusion

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MalaCards based summary: Retinal Vascular Occlusion, also known as retinal vascular occlusion, unspecified, is related to retinal artery occlusion and retinal vein occlusion. An important gene associated with Retinal Vascular Occlusion is F5 (coagulation factor V (proaccelerin, labile factor)), and among its related pathways are Integrated Breast Cancer Pathway and Hemostasis. The compounds kaolin and coumarins have been mentioned in the context of this disorder. Affiliated tissues include eye, and related mouse phenotypes are integument and cardiovascular system.

Aliases & Classifications for Retinal Vascular Occlusion

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Sources:
9Disease Ontology, 43Novoseek, 60UMLS, 55SNOMED-CT, 27ICD9CM, 38NCIt, 25ICD10
See all sources

Retinal Vascular Occlusion, Aliases & Descriptions:

Name: Retinal Vascular Occlusion 9 43 60
Retinal Vascular Occlusion, Unspecified 9
Unspecified Retinal Vascular Occlusion 9
 
Retinal Vascular Occlusion Nos 9
Retinal Vasc. Occlusion 9


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Eye diseases, Cardiovascular diseases


External Ids:

Disease Ontology9 DOID:1729
ICD9CM27 362.3, 362.30
NCIt38 C34980
ICD1025 H34, H34.9

Related Diseases for Retinal Vascular Occlusion

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Diseases related to Retinal Vascular Occlusion via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 62)
idRelated DiseaseScoreTop Affiliating Genes
1retinal artery occlusion30.8APOH
2retinal vein occlusion30.7F5, APOH, VEGFA
3thrombophilia30.5F5, SELP, APOH
4central retinal vein occlusion30.3VEGFA, APOH, F5
5blindness30.3RHO, VEGFA
6antiphospholipid syndrome30.1F5, SELP, APOH
7retinitis11.1
8quebec platelet disorder10.5F5
9sneddon syndrome10.4APOH
10patent foramen ovale10.4F5
11thrombophlebitis10.4APOH
12endophthalmitis10.4VEGFA
13hepatic vein thrombosis10.4PIGA
14mondor disease10.3APOH, F5
15hypoprothrombinemia10.3F5, APOH
16budd-chiari syndrome10.3APOH, F5
17thrombophilia due to antithrombin iii deficiency10.3APOH, F5
18intracranial thrombosis10.3APOH, F5
19factor xii deficiency10.3F5, APOH
20severe pre-eclampsia10.2APOH, F5
21protein s deficiency10.2APOH, F5
22hellp syndrome10.2APOH, F5
23protein c deficiency10.2APOH, F5
24thrombophilia due to activated protein c resistance10.2APOH, F5
25ovarian hyperstimulation syndrome10.2VEGFA, F5
26pulmonary embolism10.2APOH, F5
27pregnancy loss, recurrent 110.2F5, APOH
28behcet's disease10.2APOH, F5
29exfoliation syndrome10.2
30atherosclerosis10.2
31ischemic optic neuropathy10.2
32paroxysmal nocturnal hemoglobinuria10.2
33retinitis pigmentosa10.2
34thrombotic thrombocytopenic purpura10.2
35branch retinal artery occlusion10.2
36central retinal artery occlusion10.2
37hemiplegia10.2
38hemoglobinuria10.2
39neuropathy10.2
40papilledema10.2
41purpura10.2
42macular degeneration, age-related, 110.1RHO, VEGFA
43lupus erythematosus10.1APOH, F5
44von willebrand's disease10.1SELP, F5
45hemophilia a10.1F5, SELP
46hemolytic anemia10.1APOH, PIGA
47microvascular complications of diabetes 510.1RHO, VEGFA
48thrombotic thrombocytopenic purpura, acquired10.0APOH, SELP
49acute respiratory distress syndrome10.0SELP, F5
50cerebrovascular disease10.0APOH, SELP

Graphical network of the top 20 diseases related to Retinal Vascular Occlusion:



Diseases related to retinal vascular occlusion

Symptoms for Retinal Vascular Occlusion

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Drugs & Therapeutics for Retinal Vascular Occlusion

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Drug clinical trials:

Search ClinicalTrials for Retinal Vascular Occlusion

Search NIH Clinical Center for Retinal Vascular Occlusion

Genetic Tests for Retinal Vascular Occlusion

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Anatomical Context for Retinal Vascular Occlusion

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MalaCards organs/tissues related to Retinal Vascular Occlusion:

31
Eye

Animal Models for Retinal Vascular Occlusion or affiliated genes

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MGI Mouse Phenotypes related to Retinal Vascular Occlusion:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00107718.2F5, SELP, VEGFA, PIGA
2MP:00053858.1F5, RHO, SELP, VEGFA
3MP:00053868.1F5, SELP, VEGFA, PIGA
4MP:00053767.9VEGFA, APOH, SELP, RHO, F5
5MP:00036317.7F5, RHO, SELP, VEGFA, PIGA
6MP:00053977.7PIGA, VEGFA, SELP, RHO
7MP:00107687.6PIGA, VEGFA, APOH, SELP, F5

Publications for Retinal Vascular Occlusion

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Articles related to Retinal Vascular Occlusion:

(show top 50)    (show all 69)
idTitleAuthorsYear
1
Oral contraceptive pills: A risk factor for retinal vascular occlusion in in-vitro fertilization patients. (23869159)
2013
2
Pipeline embolization device: a new source for embolic retinal vascular occlusion. (24051422)
2013
3
Impact of cilostazol on the progression of carotid atherosclerosis in patients with retinal vascular occlusion. (24034133)
2013
4
Thrombophilia and retinal vascular occlusion. (22969282)
2012
5
Central retinal vascular occlusion associated with acute retinal necrosis. (22491922)
2012
6
Retinal vascular occlusion after vitrectomy with retrobulbar anesthesia-observational case series and survey of literature. (21850439)
2011
7
Retinal vascular occlusion during in vitro fertilization. (25390129)
2010
8
Factor V Leiden mutation with retinal vascular occlusion. (21199226)
2010
9
Retinal vascular occlusion syndromes. (19584622)
2009
10
Retinal vascular occlusions: an interdisciplinary challenge. (19626196)
2008
11
Low density lipoprotein triglycerides and lipoprotein(a) are risk factors for retinal vascular occlusion. (17481600)
2007
12
Role of hyperhomocystinemia in retinal vascular occlusive disease. (17164500)
2007
13
Retinal vascular occlusion following ocular contusion. (15931542)
2005
14
Retinal vascular occlusion following traumatic hyphema and glaucoma, as a presenting sign of sickle cell trait. (16011069)
2005
15
Retinal vascular occlusion with overlying vitreous hemorrhage masquerading as a tumor. (15710833)
2005
16
Retinal vascular occlusion in patients infected with human immunodeficiency virus. (16141865)
2005
17
Impairment of homocysteine metabolism in patients with retinal vascular occlusion and non-arteritic ischemic optic neuropathy. (16197292)
2005
18
Central retinal vascular occlusion by orbital pseudotumor. (15187672)
2004
19
Factor V Leiden mutation does not correlate with retinal vascular occlusion in white patients with BehAset's disease. (12881356)
2003
20
Unilateral peripheral retinal vascular occlusion in a young Japanese woman with neurofibromatosis-1. (12972769)
2003
21
Retinal vascular occlusion and primary antiphospholipid syndrome. Report of 2 cases]. (11912840)
2001
22
The electroretinogram in patients with retinal vascular occlusion. (12567597)
2001
23
Systemic disorders associated with retinal vascular occlusion. (11141642)
2000
24
Retinal vascular occlusion and deficiencies in the protein C pathway. (10653431)
2000
25
Retinal vascular occlusion and deficiencies in the protein C pathway. (10653432)
2000
26
Retinal vascular occlusion and deficiencies in the protein C pathway. (10482096)
1999
27
Genetic thrombophilia in patients with retinal vascular occlusion. (11456253)
1999
28
Abnormalities in haemorheological factors and lipoprotein (a) in retinal vascular occlusion: implications for increased vascular risk. (9683948)
1998
29
Visual field loss caused by retinal vascular occlusion after vitrectomy surgery. (9152086)
1997
30
Cocaine-associated retinal vascular occlusion: report of two cases. (8059789)
1994
31
Lipoprotein (a): a risk factor for retinal vascular occlusion. (1477637)
1992
32
The investigation of patients with retinal vascular occlusion. (2209910)
1990
33
Massive bilateral retinal vascular occlusion. (2475899)
1989
34
Retinal vascular occlusion without retrobulbar or optic nerve sheath hemorrhage after retrobulbar injection of lidocaine. (3231409)
1988
35
Experimental retinal vascular occlusion. II. A clinico-pathologic correlative study of simultaneous occlusion of central retinal vein and artery. (3721721)
1986
36
Experimental retinal vascular occlusion. III. An ultrastructural study of simultaneous occlusion of central retinal vein and artery. (3721722)
1986
37
Ocular neovascularization with retinal vascular occlusion-III. Incidence of ocular neovascularization with retinal vein occlusion. (6192376)
1983
38
Ocular neovascularization with retinal vascular occlusion. I. Association with experimental retinal vein occlusion. (6175297)
1982
39
Ocular neovascularization with retinal vascular occlusion. II. Occurrence in central and branch retinal artery occlusion. (6182865)
1982
40
Experimental retinal vascular occlusion. I. Pathogenesis of central retinal vein occlusion. (415709)
1978
41
Acute infantile hemiplegia associated with ipsilateral retinal vascular occlusion. (4843527)
1974
42
Sudden blindness after ventriculography. Bilateral retinal vascular occlusion superimposed on papilledema. (4546564)
1974
43
Abnormal glucose tolerance in association with retinal vascular occlusion. (4752297)
1973
44
Retinal vascular occlusion in the cat by photocoagulation: trial of a new instrument. (4753336)
1973
45
Fluorescein studies in retinal vascular occlusion. (5635899)
1968
46
Microangiography in retinal vascular occlusion [abstract]. (20919019)
1968
47
CURRENT DEVELOPMENTS IN OPHTHALMOLOGY. FIBRINOLYSIS IN RETINAL VASCULAR OCCLUSION. (14190868)
1964
48
INTRAVENOUS STREPTOKINASE IN THE TREATMENT OF RETINAL VASCULAR OCCLUSION. (14159485)
1964
49
Retinal vascular occlusion associated with gastro-intestinal hemorrhage. (13977191)
1962
50
Anticoagulant therapy in retinal vascular occlusion. (18136778)
1949

Variations for Retinal Vascular Occlusion

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Expression for genes affiliated with Retinal Vascular Occlusion

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Search GEO for disease gene expression data for Retinal Vascular Occlusion.

Pathways for genes affiliated with Retinal Vascular Occlusion

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Pathways related to Retinal Vascular Occlusion according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.4RHO, VEGFA
2
Show member pathways
8.7F5, SELP, VEGFA
3
Show member pathways
8.7F5, SELP, VEGFA

Compounds for genes affiliated with Retinal Vascular Occlusion

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Compounds related to Retinal Vascular Occlusion according to GeneCards Suite gene sharing:

(show top 50)    (show all 70)
idCompoundScoreTop Affiliating Genes
1kaolin4310.0F5, APOH
2coumarins4310.0APOH, F5
3cardiolipin43 1210.9APOH, F5
4phosphatidylethanolamine43 1210.8F5, APOH
5fluorescein43 1210.8F5, VEGFA
6batroxobin439.7F5, SELP
7tyrosine sulfate439.7F5, SELP
8bivalirudin43 1210.7F5, SELP
9argatroban43 1210.6SELP, F5
10penicillin439.6F5, SELP
11ristocetin439.6SELP, F5
1211-dehydrothromboxane b2439.6APOH, SELP
13ticlopidine43 1210.5SELP, APOH
14ptca439.5SELP, APOH
15desmopressin43 59 28 1212.5F5, SELP
16fluorochrome439.5RHO, SELP
17quinacrine43 1210.5SELP, APOH
18hirudin439.5F5, SELP
19phosphatidylcholine439.5APOH, RHO, F5
20candesartan43 49 28 1212.4SELP, VEGFA
21phospholipid439.4F5, RHO, APOH
22infliximab43 49 1211.4APOH, VEGFA
23protamine439.4F5, SELP
24txb2439.4APOH, SELP
25mycophenolate mofetil43 49 1211.4F5, SELP
26dermatan sulfate439.3F5, SELP
27deoxyribonucleic acid439.3F5, APOH
28dextran sulfate439.2F5, SELP, APOH
29warfarin43 49 24 1212.2F5, SELP, APOH
30kininogen439.2APOH, SELP, F5
31homocysteine43 2410.2F5, SELP, APOH
32cocaine43 1210.2F5, SELP, APOH
33aspirin43 49 28 2412.2F5, SELP, APOH
34halothane43 49 28 1212.2SELP, RHO, F5
35atorvastatin43 49 28 24 1213.1VEGFA, SELP, F5
36simvastatin43 49 59 28 24 1214.1VEGFA, SELP, F5
37fibrinogen439.1APOH, SELP, F5
38epinephrine43 24 1211.1F5, RHO, SELP
39polysaccharide439.1F5, RHO, SELP
40lactate439.0F5, SELP, APOH
41ly294002438.9VEGFA, SELP, RHO
42cyclophosphamide43 49 1210.9F5, APOH, VEGFA, PIGA
43creatinine438.8APOH, SELP, F5
44aspartate438.7F5, RHO, SELP
45phosphatidylserine43 28 1210.7APOH, SELP, RHO, F5
46arginine438.7F5, RHO, SELP, APOH
47estrogen438.6VEGFA, APOH, SELP, F5
48prostacyclin438.2F5, RHO, SELP, APOH, VEGFA
49heparin43 28 24 1211.2VEGFA, APOH, SELP, RHO, F5
50vegf438.2F5, RHO, SELP, APOH, VEGFA

GO Terms for genes affiliated with Retinal Vascular Occlusion

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Cellular components related to Retinal Vascular Occlusion according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1platelet alpha granule lumenGO:00310939.5F5, VEGFA
2extracellular spaceGO:00056158.0F5, SELP, APOH, VEGFA

Biological processes related to Retinal Vascular Occlusion according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of leukocyte migrationGO:00026879.0SELP, VEGFA
2platelet degranulationGO:00025768.7F5, SELP, VEGFA
3blood coagulationGO:00075968.7VEGFA, SELP, F5
4platelet activationGO:00301688.4SELP, F5, VEGFA

Molecular functions related to Retinal Vascular Occlusion according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1glycoprotein bindingGO:00019489.2SELP, APOH
2heparin bindingGO:00082018.6SELP, APOH, VEGFA
3protein bindingGO:00055156.8PIGA, VEGFA, APOH, SELP, RHO, F5

Products for genes affiliated with Retinal Vascular Occlusion

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Retinal Vascular Occlusion

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet