Aliases & Classifications for Retinitis

Aliases & Descriptions for Retinitis:

Name: Retinitis 12 52 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:3612
ICD10 33 H30.9
MeSH 42 D012173
NCIt 47 C115993
UMLS 69 C0035333

Summaries for Retinitis

MalaCards based summary : Retinitis is related to retinitis pigmentosa 34 and leber congenital amaurosis 8. An important gene associated with Retinitis is RPGR (Retinitis Pigmentosa GTPase Regulator), and among its related pathways/superpathways are Development_Thrombopoetin signaling via JAK-STAT pathway and the visual cycle I (vertebrates). The drugs Cidofovir and Ganciclovir have been mentioned in the context of this disorder. Affiliated tissues include eye, endothelial and retina, and related phenotypes are Increased HPV16-GFP infection and nervous system

Wikipedia : 71 Retinitis is inflammation of the retina in the eye, which may lead to blindness. Retinitis may be caused... more...

Related Diseases for Retinitis

Diseases related to Retinitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 1375)
id Related Disease Score Top Affiliating Genes
1 retinitis pigmentosa 34 33.1 RHO RPE65
2 leber congenital amaurosis 8 31.7 CRB1 RP9
3 choriodal dystrophy, central areolar 2 31.1 PRPH2 RHO RP9
4 macular degeneration, age-related, 6 30.8 RPGR RPGRIP1
5 leber congenital amaurosis 9 29.8 CRB1 RPE65 RPGRIP1
6 retinitis pigmentosa 12.3
7 retinal detachment 12.2
8 retinitis pigmentosa 3 12.1
9 central retinal vein occlusion 12.1
10 retinitis pigmentosa 2 12.1
11 retinitis pigmentosa 9 12.1
12 retinitis pigmentosa 1 12.1
13 central retinal artery occlusion 12.1
14 retinitis pigmentosa 17 12.0
15 retinitis pigmentosa 28 12.0
16 retinal dystrophy with inner retinal dysfunction and ganglion cell abnormalities 12.0
17 retinal disease 12.0
18 cytomegalovirus retinitis 12.0
19 infantile cerebellar-retinal degeneration 12.0
20 retinitis pigmentosa-12, autosomal recessive 12.0
21 retinitis pigmentosa 7 and digenic 12.0
22 retinitis pigmentosa 67 12.0
23 retinal vasculitis 12.0
24 retinitis pigmentosa 11 12.0
25 retinitis pigmentosa 41 12.0
26 retinal degeneration 12.0
27 retinitis pigmentosa 38 12.0
28 retinitis pigmentosa 14 12.0
29 retinitis pigmentosa-50 12.0
30 branch retinal artery occlusion 12.0
31 retinitis pigmentosa 69 12.0
32 retinitis pigmentosa 20 12.0
33 retinitis pigmentosa 19 12.0
34 retinitis pigmentosa 18 12.0
35 retinitis pigmentosa 35 12.0
36 retinitis pigmentosa 33 12.0
37 retinitis pigmentosa 26 12.0
38 retinitis pigmentosa 4, autosomal dominant or recessive 12.0
39 retinitis pigmentosa 25 12.0
40 retinitis pigmentosa 31 12.0
41 retinitis pigmentosa 13 12.0
42 retinitis pigmentosa 36 12.0
43 retinitis pigmentosa 30 12.0
44 retinitis pigmentosa 59 12.0
45 retinitis pigmentosa 58 12.0
46 retinitis pigmentosa 47 12.0
47 retinitis pigmentosa 55 12.0
48 retinitis pigmentosa-40 12.0
49 retinitis pigmentosa 49 12.0
50 retinitis pigmentosa 43 12.0

Graphical network of the top 20 diseases related to Retinitis:



Diseases related to Retinitis

Symptoms & Phenotypes for Retinitis

GenomeRNAi Phenotypes related to Retinitis according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased HPV16-GFP infection GR00350-A 8.92 FLVCR1 IMPDH1 RP2 RPE65

MGI Mouse Phenotypes related to Retinitis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 nervous system MP:0003631 9.85 CRB1 PRPH2 RHO RLBP1 RP1 RP1L1
2 pigmentation MP:0001186 9.56 CRB1 PRPF3 PRPF31 PRPH2 RHO RLBP1
3 vision/eye MP:0005391 9.47 RHO RLBP1 RP1 RP1L1 RP2 RPE65

Drugs & Therapeutics for Retinitis

Drugs for Retinitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 234)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cidofovir Approved Phase 4,Phase 2,Phase 3,Phase 1 113852-37-2 60613
2
Ganciclovir Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 82410-32-0 3454
3
Foscarnet Approved Phase 4,Phase 3,Phase 2,Phase 1 63585-09-1, 4428-95-9 3415
4
Probenecid Approved Phase 4,Phase 2,Phase 1 57-66-9 4911
5
Phosphonoacetic Acid Experimental Phase 4,Phase 3,Phase 2,Phase 1 4408-78-0 546
6 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1
7 Antirheumatic Agents Phase 4,Phase 3,Phase 2,Phase 1
8 Antiviral Agents Phase 4,Phase 3,Phase 2,Phase 1
9 Ganciclovir triphosphate Phase 4,Phase 3,Phase 2,Phase 1
10 Nucleic Acid Synthesis Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
11 Anti-Retroviral Agents Phase 4,Phase 3,Phase 2,Phase 1
12 Reverse Transcriptase Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
13 Renal Agents Phase 4,Phase 2,Phase 1
14
Valganciclovir Approved, Investigational Phase 3,Phase 2 175865-60-8 64147
15
Clindamycin Approved, Vet_approved Phase 3 18323-44-9 29029
16
Dexamethasone Approved, Investigational, Vet_approved Phase 3,Phase 2 50-02-2 5743
17
Methylprednisolone Approved, Vet_approved Phase 3 83-43-2 6741
18
Prednisolone Approved, Vet_approved Phase 3 50-24-8 5755
19
Pyrimethamine Approved, Vet_approved Phase 3 58-14-0 4993
20
Sulfadiazine Approved, Vet_approved Phase 3 68-35-9 5215
21
Celecoxib Approved, Investigational Phase 3 169590-42-5 2662
22
Spironolactone Approved Phase 2, Phase 3,Phase 1 1952-01-7, 52-01-7 5833
23
Eplerenone Approved Phase 2, Phase 3 107724-20-9 150310 443872
24
Folic Acid Approved, Nutraceutical, Vet_approved Phase 3,Phase 1,Phase 2,Early Phase 1 59-30-3 6037
25
leucovorin Approved, Nutraceutical Phase 3,Phase 1,Phase 2 58-05-9 54575, 6560146 143
26
Lutein Approved, Nutraceutical Phase 3,Phase 1,Phase 2 127-40-2 6433159 5368396
27
Vitamin A Approved, Nutraceutical, Vet_approved Phase 3,Phase 1 11103-57-4, 68-26-8 445354
28
Vitamin E Approved, Nutraceutical, Vet_approved Phase 3 59-02-9 14985
29 Anti-Bacterial Agents Phase 3,Phase 1,Phase 2
30 Antiemetics Phase 3,Phase 2
31 Anti-Inflammatory Agents Phase 3,Phase 2
32 Antimalarials Phase 3
33 Antineoplastic Agents, Hormonal Phase 3,Phase 2
34 Antiparasitic Agents Phase 3
35 Antiprotozoal Agents Phase 3
36 Autonomic Agents Phase 3,Phase 2,Phase 1
37 BB 1101 Phase 3,Phase 2
38 Clindamycin palmitate Phase 3
39 Clindamycin phosphate Phase 3
40 Dexamethasone 21-phosphate Phase 3,Phase 2
41 Dexamethasone acetate Phase 3,Phase 2 1177-87-3
42 Folic Acid Antagonists Phase 3,Phase 1,Phase 2
43 Gastrointestinal Agents Phase 3,Phase 2
44 glucocorticoids Phase 3,Phase 2
45 HIV Protease Inhibitors Phase 3,Phase 2
46 Hormone Antagonists Phase 3,Phase 2,Phase 1
47 Hormones Phase 3,Phase 2,Phase 1
48 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3,Phase 2,Phase 1
49 Methylprednisolone acetate Phase 3
50 Methylprednisolone Hemisuccinate Phase 3

Interventional clinical trials:

(show top 50) (show all 213)
id Name Status NCT ID Phase
1 Comparison of Two Drugs, Cidofovir and Ganciclovir, in Treating Patients With AIDS Who Have CMV Retinitis Completed NCT00000894 Phase 4
2 The Role of Capsular Tension Ring (CTR) in Anterior Capsular Contraction Completed NCT00717080 Phase 4
3 A Multicenter Study of Oral Versus Intravenous Hydration in AIDS Patients With CMV Retinitis Treated With Foscavir (Foscarnet Sodium) Completed NCT00002125 Phase 4
4 Pharmacokinetics of Cidofovir During Continuous Venovenous Hemofiltration Completed NCT01866397 Phase 4
5 Valganciclovir in Patients With CMV Retinitis and AIDS Who Cannot Take Drugs by Injection Unknown status NCT00017784 Phase 3
6 To Compare Intravitreal Clindamycin & Dexamethasone With Classic Treatment of Toxoplasmic Retinochoroiditis Unknown status NCT00372294 Phase 3
7 Clinical Trial of Lutein for Patients With Retinitis Pigmentosa Receiving Vitamin A Completed NCT00346333 Phase 3
8 Randomized Trial for Retinitis Pigmentosa Completed NCT00000116 Phase 3
9 Studies of the Ocular Complications of AIDS (SOCA)--HPMPC Peripheral CMV Retinitis Trial (HPCRT) Completed NCT00000142 Phase 2, Phase 3
10 A Randomized, Controlled Study of Intravenous Ganciclovir Therapy for Peripheral Cytomegalovirus Retinitis in Patients With AIDS Completed NCT00000688 Phase 3
11 A Treatment Protocol for the Use of Intravenous Ganciclovir in AIDS Patients With Immediately Sight-Threatening CMV Retinitis Completed NCT00000698 Phase 3
12 Studies of the Ocular Complications of AIDS (SOCA)--Foscarnet-Ganciclovir CMV Retinitis Trial (FGCRT) Completed NCT00000136 Phase 3
13 Studies of the Ocular Complications of AIDS (SOCA)--Monoclonal Antibody CMV Retinitis Trial (MACRT) Completed NCT00000135 Phase 2, Phase 3
14 Phase III Ganciclovir +/- rGM-CSF for AIDS-Related CMV Retinitis Completed NCT00002070 Phase 3
15 Randomized Trial of Vitamin A and Vitamin E Supplementation for Retinitis Pigmentosa Completed NCT00000114 Phase 3
16 Studies of Ocular Complications of AIDS (SOCA)--Ganciclovir-Cidofovir CMV Retinitis Trial (GCCRT) Completed NCT00000143 Phase 3
17 Studies of the Ocular Complications of AIDS (SOCA)--Cytomegalovirus Retinitis Retreatment Trial (CRRT) Completed NCT00000134 Phase 3
18 Ganciclovir Implant Study for Cytomegalovirus Retinitis Completed NCT00000118 Phase 3
19 A Comparison of Valganciclovir and Ganciclovir in the Treatment of Cytomegalovirus (CMV) of the Eyes Completed NCT00002377 Phase 3
20 Valganciclovir in Prevention of Cytomegalovirus (CMV) Reactivation Following Allogeneic-Stem Cell Transplantation (SCT) Completed NCT00330018 Phase 3
21 Ozurdex for Macular Edema Post Membrane Peeling Completed NCT01273727 Phase 2, Phase 3
22 Laser and Medical Treatment of Diabetic Macular Edema Completed NCT00050479 Phase 3
23 The Effect of Oral Administration of 9-cis β Carotene Rich Powder of the Alga Dunaliella Bardawil Recruiting NCT01680510 Phase 2, Phase 3
24 Setmelanotide Phase 2 Treatment Trial in Patients With Rare Genetic Disorders of Obesity Recruiting NCT03013543 Phase 2, Phase 3
25 A Study of the Beneficial Effects of Eplerenone on Central Serous Chorioretinopathy Not yet recruiting NCT02215330 Phase 2, Phase 3
26 Phase III Efficacy and Safety Clinical Study of UF-021 for Treatment of Retinitis Pigmentosa Terminated NCT01786395 Phase 3
27 Clinical Study to Evaluate Safety and Efficacy of BMMNC in Retinitis Pigmentosa Unknown status NCT01914913 Phase 1, Phase 2
28 A Dose Ranging Study to Evaluate the Safety and Potential Efficacy of rhNGF in Patients With Retinitis Pigmentosa (RP) Unknown status NCT02110225 Phase 1, Phase 2
29 Autologous Bone Marrow-Derived Stem Cells Transplantation For Retinitis Pigmentosa Completed NCT01560715 Phase 2
30 Trial of Oral Valproic Acid for Retinitis Pigmentosa Completed NCT01233609 Phase 2
31 A Study of Encapsulated Cell Technology (ECT) Implant for Patients With Late Stage Retinitis Pigmentosa Completed NCT00447993 Phase 2
32 Safety Study in Retinal Transplantation for Retinitis Pigmentosa. Completed NCT00345917 Phase 2
33 CMV Retinitis Retreatment Trial Completed NCT00000766 Phase 2
34 A Study of Encapsulated Cell Technology (ECT) Implant for Participants With Early Stage Retinitis Pigmentosa Completed NCT00447980 Phase 2
35 Effects of Lutein in Retinitis Pigmentosa Completed NCT00029289 Phase 1, Phase 2
36 Study of Oral Minocycline in Treating Bilateral Cystoid Macular Edema Associated With Retinitis Pigmentosa Completed NCT02140164 Phase 1, Phase 2
37 A Randomized Comparison of Intravitreal ISIS 2922 Plus Ganciclovir Versus Ganciclovir as Treatment for Patients With Cytomegalovirus Retinitis ( CMVR ) Completed NCT00002156 Phase 2
38 A Study of Viracept in AIDS Patients With Cytomegalovirus Retinitis Completed NCT00002169 Phase 2
39 A Phase II Dose-Ranging, Open-Labelled Trial of Foscarnet Salvage Therapy for AIDS Patients With Sight-Threatening CMV Retinitis Who Cannot Be Treated With Ganciclovir Due To Myelosuppression or Treatment Failure Completed NCT00000691 Phase 2
40 DHA and X-Linked Retinitis Pigmentosa Completed NCT00100230 Phase 2
41 An Exploratory Study to Evaluate the Safety of Brimonidine Intravitreal Implant in Patients With Retinitis Pigmentosa Completed NCT00661479 Phase 1, Phase 2
42 Phase II Randomized Study of Cidofovir for Peripheral Cytomegalovirus Retinitis Completed NCT00004794 Phase 2
43 The Safety and Effectiveness of ISIS 2922 in Patients With AIDS Who Have Cytomegalovirus (CMV) of the Eyes Completed NCT00002356 Phase 2
44 The Safety and Effectiveness of Cidofovir in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS Completed NCT00002437 Phase 2
45 Comparison of Two Methods in the Treatment of Cytomegalovirus of the Eyes in Patients With AIDS Completed NCT00001061 Phase 2
46 Efficacy and Safety of Oral Valproic Acid for Retinitis Pigmentosa Completed NCT01399515 Phase 2
47 Feasibility Study of a Chronic Retinal Stimulator in Retinitis Pigmentosa Completed NCT00279500 Phase 1, Phase 2
48 A Phase II/III Trial of Human Anti-CMV Monoclonal Antibody MSL 109 (MACRT) Completed NCT00000836 Phase 2
49 The Safety and Effectiveness of Ganciclovir in the Prevention of Cytomegalovirus (CMV) of the Eyes and Disease of the Stomach and Intestines in Patients With HIV Completed NCT00001034 Phase 2
50 The Safety and Effectiveness of FIAC in the Treatment of Cytomegalovirus (CMV) in Patients With AIDS Completed NCT00000981 Phase 2

Search NIH Clinical Center for Retinitis

Genetic Tests for Retinitis

Anatomical Context for Retinitis

MalaCards organs/tissues related to Retinitis:

39
Eye, Endothelial, Retina, Testes, T Cells, Brain, Bone

Publications for Retinitis

Articles related to Retinitis:

(show top 50) (show all 11632)
id Title Authors Year
1
Cytomegalovirus Retinitis in Patients With Acquired Immunodeficiency Syndrome After Initiating Antiretroviral Therapy. ( 27984023 )
2017
2
A novel mutation in the dominantly inherited TOPORS gene supports haploinsufficiency as the mechanism of retinitis pigmentosa. ( 28453362 )
2017
3
Whole-Exome Sequencing Identifies Biallelic IDH3A Variants as a Cause of Retinitis Pigmentosa Accompanied by Pseudocoloboma. ( 28412069 )
2017
4
Robot-assisted retinal vein cannulation in an inA vivo porcine retinal vein occlusion model. ( 28084059 )
2017
5
Primary Retinal Detachment Surgery: Changes in Treatment and Outcome in an Austrian Tertiary Eye Center. ( 28068654 )
2017
6
Safety and acceptability of an organic light-emitting diode sleep mask as a potential therapy for retinal disease. ( 27983728 )
2017
7
Myeloid differentiation protein 2-dependent mechanisms in retinal ischemia-reperfusion injury. ( 28063877 )
2017
8
Retinal segmented layers with strong aquaporin-4 expression suffered more injuries in neuromyelitis optica spectrum disorders compared with optic neuritis with aquaporin-4 antibody seronegativity detected by optical coherence tomography. ( 28057643 )
2017
9
Retinal Structure and Function in Eyes with Optic Nerve Hypoplasia. ( 28205530 )
2017
10
Identification of a disease-causing mutation in a Chinese patient with retinitis pigmentosa by targeted next-generation sequencing. ( 28430325 )
2017
11
CENTRAL RETINAL ARTERY OCCLUSION WITH DOUBLE CILIORETINAL ARTERY SPARING. ( 28085758 )
2017
12
Pathologic confirmation of retinal ganglion cell loss in multiple system atrophy. ( 28490649 )
2017
13
Peripheral Retinal Changes Associated withA Age-Related Macular Degeneration inA the Age-Related Eye Disease Study 2: Age-Related Eye Disease Study 2 Report Number 12 by theA Age-Related Eye Disease Study 2 Optos PEripheral RetinA (OPERA) Study Research Group. ( 28089680 )
2017
14
Juvenile X-linked retinoschisis presenting as juxtapapillary retinal fold mimicking combined hamartoma of the retina and retinal pigment epithelium. ( 28147237 )
2017
15
Correlation between miR-148 Expression in Vitreous and Severity of Rhegmatogenous Retinal Detachment. ( 28261609 )
2017
16
Assessment of ischemia in acute central retinal vein occlusion from inner retinal reflectivity on spectral domain optical coherence tomography. ( 28053503 )
2017
17
Nestin Expression in the Adult Mouse Retina with Pharmaceutically Induced Retinal Degeneration. ( 28049248 )
2017
18
ASSESSMENT OF THE RETINAL STRUCTURE IN CHILDREN WITH INCONTINENTIA PIGMENTI. ( 28085775 )
2017
19
Whole exome sequencing identified a novel single base pair insertion mutation in the EYS gene in a six generation family with retinitis pigmentosa. ( 28419563 )
2017
20
Clinical Characterization of CNGB1-Related Autosomal Recessive Retinitis Pigmentosa. ( 28056120 )
2017
21
Retinal dystrophy in two boys with Costello syndrome due to the HRAS p.Gly13Cys mutation. ( 28337834 )
2017
22
Possible protective role of the ABCA4 gene c.1268A>G missense variant in Stargardt disease and syndromic retinitis pigmentosa in a Sicilian family: Preliminary data. ( 28290600 )
2017
23
Avascular Retinal Findings in a Child With Achondroplasia. ( 28297043 )
2017
24
Mutation screening in genes known to be responsible for Retinitis Pigmentosa in 98 Small Han Chinese Families. ( 28512305 )
2017
25
Novel variants of RPGR in X-linked retinitis pigmentosa families and genotype-phenotype correlation. ( 27768226 )
2017
26
Notch signaling modulates proliferative vitreoretinopathy via regulating retinal pigment epithelial-to-mesenchymal transition. ( 27600720 )
2017
27
A Report on Molecular Diagnostic Testing for Inherited Retinal Dystrophies by Targeted Genetic Analyses. ( 28005406 )
2017
28
Type 3 Neovascularization Associated with Retinitis Pigmentosa. ( 28512428 )
2017
29
Involvement of Fra-1 in Retinal Ganglion Cell Apoptosis in Rat Light-Induced Retina Damage Model. ( 27002720 )
2017
30
Evaluation of Ophthalmic Artery Branch Retrograde Intervention in the Treatment of Central Retinal Artery Occlusion (CRAO). ( 28064304 )
2017
31
Patterns of retinal hemorrhage associated with pediatric cerebral sinovenous thrombosis. ( 28087346 )
2017
32
Iron importers Zip8 and Zip14 are expressed in retina and regulated by retinal iron levels. ( 28057442 )
2017
33
Opposing Effects of Valproic Acid Treatment Mediated by Histone Deacetylase Inhibitor Activity in Four Transgenic X. laevis Models of Retinitis Pigmentosa. ( 28490005 )
2017
34
Retinal pigmentary changes in chronic uveitis mimicking retinitis pigmentosa. ( 28523457 )
2017
35
Minireview: Fibronectin in retinal disease. ( 27798121 )
2017
36
The role of hypertension in retinal blood flow alterations in open-angle glaucoma patients. ( 28084046 )
2017
37
Complement modulation in the retinal pigment epithelium rescues photoreceptor degeneration in a mouse model of Stargardt disease. ( 28348233 )
2017
38
RETINAL DETACHMENT ASSOCIATED WITH PERIPAPILLARY STAPHYLOMA IMAGED WITH SWEPT SOURCE OPTICAL COHERENCE TOMOGRAPHY. ( 28072615 )
2017
39
Rearing Light Intensity Affects Inner Retinal Pathology in a Mouse Model of X-Linked Retinoschisis but Does Not Alter Gene Therapy Outcome. ( 28297725 )
2017
40
COMPUTER ASSISTED RETINAL VESSEL TORTUOSITY EVALUATION IN NOVEL MUTATION FABRY DISEASE: Towards New Prognostic Markers. ( 28225726 )
2017
41
SURGICAL MANAGEMENT OF RETINAL DETACHMENT IN OSTEOGENESIS IMPERFECTA: CASE REPORT AND REVIEW OF THE LITERATURE. ( 28085759 )
2017
42
A novel MERTK mutation causing retinitis pigmentosa. ( 28462455 )
2017
43
Comparison of outcomes: scleral buckling and pars plana vitrectomy versus vitrectomy alone for primary repair of rhegmatogenous retinal detachment. ( 28053500 )
2017
44
OUTER RETINAL TUBULATIONS IN CHRONIC RHEGMATOGENOUS RETINAL DETACHMENT. ( 28085760 )
2017
45
Bilateral retinitis following typhoid fever. ( 28405476 )
2017
46
Management of acute central retinal artery occlusion: Intravenous thrombolysis is feasible and safe. ( 28067616 )
2017
47
Retinitis pigmentosa-associated cystoid macular oedema: pathogenesis and avenues of intervention. ( 27913439 )
2017
48
Mutations in the PCYT1A gene are responsible for isolated forms of retinal dystrophy. ( 28272537 )
2017
49
Prothrombin polymorphism A19911G, factor V HR2 haplotype A4070G, and plasminogen activator-inhibitor-1 polymorphism 4G/5G and the risk of retinal vein occlusion. ( 28085526 )
2017
50
PARACENTRAL ACUTE MIDDLE MACULOPATHY AND DEEP RETINAL CAPILLARY PLEXUS INFARCTION SECONDARY TO REPERFUSED CENTRAL RETINAL ARTERY OCCLUSION. ( 27668500 )
2017

Variations for Retinitis

Expression for Retinitis

Search GEO for disease gene expression data for Retinitis.

Pathways for Retinitis

Pathways related to Retinitis according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 10.69 RHO RLBP1 RPE65
2
Show member pathways
10.54 RHO RLBP1 RPE65
3 9.91 RGR RHO

GO Terms for Retinitis

Cellular components related to Retinitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cilium GO:0005929 9.67 RP1 RP2 RPGR RPGRIP1
2 axoneme GO:0005930 9.5 RP1 RP1L1 RPGRIP1
3 photoreceptor inner segment GO:0001917 9.43 CERKL RHO RP1
4 viral nucleocapsid GO:0019013 9.4 PRPF31 SNRNP200
5 photoreceptor connecting cilium GO:0032391 9.33 RP1 RP1L1 RPGRIP1
6 U4/U6 x U5 tri-snRNP complex GO:0046540 9.13 PRPF3 PRPF31 SNRNP200
7 photoreceptor outer segment GO:0001750 9.1 CERKL PRPH2 RHO RP1 RP1L1 RPGR

Biological processes related to Retinitis according to GeneCards Suite gene sharing:

(show all 17)
id Name GO ID Score Top Affiliating Genes
1 RNA splicing GO:0008380 9.83 PRPF3 PRPF31 RP9 SNRNP200
2 response to stimulus GO:0050896 9.76 EYS RGR RHO RLBP1 RP1 RPE65
3 retinoid metabolic process GO:0001523 9.61 RHO RLBP1 RPE65
4 response to light stimulus GO:0009416 9.57 RHO RPE65
5 eye photoreceptor cell development GO:0042462 9.56 CRB1 RPGRIP1
6 detection of light stimulus involved in visual perception GO:0050908 9.55 EYS RPE65
7 axoneme assembly GO:0035082 9.54 RP1 RP1L1
8 protein-chromophore linkage GO:0018298 9.51 RGR RHO
9 photoreceptor cell maintenance GO:0045494 9.5 RHO RP1 RP1L1
10 spliceosomal tri-snRNP complex assembly GO:0000244 9.49 PRPF3 PRPF31
11 retina morphogenesis in camera-type eye GO:0060042 9.48 RP1 RPE65
12 phototransduction, visible light GO:0007603 9.46 RHO RP1
13 retina development in camera-type eye GO:0060041 9.43 PRPH2 RHO RP1 RP1L1 RPE65 RPGRIP1
14 vitamin A metabolic process GO:0006776 9.4 RLBP1 RPE65
15 cellular response to light stimulus GO:0071482 9.37 RHO RP1
16 visual perception GO:0007601 9.36 EYS PRPH2 RGR RHO RLBP1 RP1
17 photoreceptor cell development GO:0042461 9.26 RP1 RP1L1

Molecular functions related to Retinitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 photoreceptor activity GO:0009881 8.62 RGR RHO

Sources for Retinitis

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