MCID: RHS001
MIFTS: 35

Rh Isoimmunization malady

Summaries for Rh Isoimmunization

About this section
Sources:
63Wikipedia, 32MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
Wikipedia:63 Rh disease (also known as Rhesus isoimmunisation, Rh (D) disease, Rhesus incompatibility, Rhesus... more...

MalaCards: Rh Isoimmunization, also known as rh incompatibility affecting management of mother, is related to neonatal anemia and fetal erythroblastosis. An important gene associated with Rh Isoimmunization is EPO (erythropoietin). The drug rho(d) immune globulin and the compounds succinylacetone and ribavirin have been mentioned in the context of this disorder. Affiliated tissues include placenta and heart.

Aliases & Classifications for Rh Isoimmunization

About this section
Sources:
8Disease Ontology, 10DISEASES, 44Novoseek, 60UMLS, 56SNOMED-CT, 34MeSH
See all sources

Aliases & Descriptions:

rh isoimmunization 8 10 44 60
rh incompatibility affecting management of mother 8
rhesus isoimmunization affecting pregnancy 8
rhesus isoimmunisation in pregnancy 8
rhesus isoimmunization unspecified 8
rhesus isoimmunization nos 8
rhesus isoimmunisation 8


External Ids:

Disease Ontology8 DOID:4175
MeSH34 D012203

Related Diseases for Rh Isoimmunization

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Graphical network of the top 20 diseases related to Rh Isoimmunization:



Diseases related to rh isoimmunization

Clinical Features for Rh Isoimmunization

About this section

Drugs & Therapeutics for Rh Isoimmunization

About this section
Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Rh Isoimmunization

Drug clinical trials:

Search ClinicalTrials for Rh Isoimmunization

Search NIH Clinical Center for Rh Isoimmunization

Search CenterWatch for Rh Isoimmunization

Inferred drug relations via UMLS60/NDF-RT40:

Genetic Tests for Rh Isoimmunization

About this section

Anatomical Context for Rh Isoimmunization

About this section
Sources:
32MalaCards
See all sources

MalaCards organs/tissues related to Rh Isoimmunization:

32
Placenta, Heart

Animal Models for Rh Isoimmunization or affiliated genes

About this section

Publications for Rh Isoimmunization

About this section
Sources:
50PubMed
See all sources

Articles related to Rh Isoimmunization:

(show top 50)    (show all 91)
idTitleAuthorsYear
1
Comparison between two treatment protocols with recombinant human erythropoietin (rHuEpo) in the treatment of late anemia in neonates with Rh-isoimmunization. (23173411)
2012
2
Isolated early onset anemia after rh isoimmunization: a unique presentation in 3 neonates. (20628321)
2010
3
Rh isoimmunization in Sub-Saharan Africa indicates need for universal access to anti-RhD immunoglobulin and effective management of D-negative pregnancies. (21270966)
2010
4
Ontogeny of the fetal immune system: study on pregnancies with Rh-isoimmunization and nonimmune fetal hydrops. (9884359)
1999
5
Prevention of Rh isoimmunization after spontaneous, massive fetomaternal hemorrhage. (8790318)
1996
6
Placental transfer of cefazolin and piperacillin in pregnancies remote from term complicated by Rh isoimmunization. (2119561)
1990
7
A case of Rh isoimmunization: should threatened first-trimester abortion be an indication for Rh immune globulin prophylaxis? (2115737)
1990
8
Acute Rh isoimmunization following abdominal trauma associated with late abruption placenta. (2517184)
1989
9
Intrauterine transfusion via umbilical vein in severe Rh isoimmunization. (2499936)
1989
10
Prevention of Rh isoimmunization and treatment of the compromised fetus. (3146812)
1988
11
Severe Rh isoimmunization--current methods of in utero diagnosis and treatment. (3132854)
1988
12
Umbilical cord hematoma secondary to in utero intravascular transfusion for Rh isoimmunization. (3142213)
1987
13
Fetal blood velocities in Rh isoimmunization: relationship to gestational age and to fetal hematocrit. (2942811)
1986
14
Compliance with postpartum Rh isoimmunization prophylaxis in Alberta. (2996738)
1985
15
Circulating placental proteins in pregnancies complicated by RH isoimmunization. (6429588)
1984
16
Clinical experience with the prevention of Rh-isoimmunization: a historical comparative analysis. (6202159)
1984
17
Rh isoimmunization following abdominal trauma: a case report. (6430091)
1984
18
Rh isoimmunization related to amniocentesis. (6419606)
1983
19
Rh isoimmunization following genetic amniocentesis. (6815628)
1982
20
Rh isoimmunization: a 24 year experience at Duke University Medical Center. (6791500)
1981
21
Plasmapheresis as an adjunct to management of Rh isoimmunization. (7192839)
1981
22
Ultrasonographic diagnosis of intervillous thrombosis related to Rh isoimmunization. (119677)
1979
23
RH isoimmunization prevention program in a community hospital. (106231)
1979
24
The management of Rh-Isoimmunization. (98742)
1978
25
Clinical observation of the prevention of RH isoimmunization with immunoglobulin anti-D. (4219865)
1974
26
Sex ratio in Rh incompatibility and Rh isoimmunization. (4125603)
1973
27
Oestriol conjugates in amniotic fluid. Qualitative and quantitative aspects, including preliminary studies in Rh isoimmunization. (4353745)
1973
28
Rh isoimmunization in ruptured pregnancy. (5083898)
1972
29
Ten-year experience with high titer anti-D plasma for the prevention of Rh isoimmunization. (4628388)
1972
30
Liquor examination in the management of RH isoimmunization. (4999069)
1971
31
Reduction of perinatal mortality from Rh isoimmunization. (5000821)
1971
32
Significance of mid-zone fluctuations in amniotic fluid spectrophotometric analysis for Rh-isoimmunization. (5416701)
1970
33
Estriol conjugates in amniotic fluid in normal pregnancies and Rh-isoimmunization. (4330538)
1970
34
Haemolytic disease of the newborn due to Rh-isoimmunization: the role of free anti-D antibodies in bilirubin rebound. (5004392)
1970
35
Some epidemiological aspects of the prevention of Rh isoimmunization. (5003520)
1970
36
High-titer anti-D plasma for the prevention of Rh isoimmunization. (4988960)
1970
37
Management of patients with Rh isoimmunization based on amniotic fluid examination. (5766484)
1969
38
Free anti-D antibody in haemolytic disease of the newborn due to Rh-isoimmunization. (5393080)
1969
39
Prevention of Rh isoimmunization. (4973031)
1968
40
Amniotic fluid spectrophotometry, urinary estrogen estimations, and intrauterine transfusion in severe Rh isoimmunization. (5675874)
1968
41
Prevention of Rh isoimmunization. Progress report of the clinical trial in mothers. (4163377)
1967
42
Prevention of Rh isoimmunization by injection of anti-D antibody. (6061830)
1967
43
Recent progress in the management of Rh isoimmunization. (4382668)
1967
44
Intrauterine transfusion in Rh-isoimmunization. (4964132)
1967
45
EFFECT OF ABO INCOMPATIBILITY ON PREGNANCY-INDUCED RH ISOIMMUNIZATION. (14105011)
1964
46
CURRENT COMCEPTS IN THE MANAGEMENT OF THE PREGNANCY COMPLICATED BY RH ISOIMMUNIZATION. (14076474)
1963
47
The protective action of ABO incompatibility on Rh isoimmunization and Rh hemolytic disease; theoretical and clinical implications. (13641945)
1959
48
RH isoimmunization associated with regurgitation jaundice beginning in utero; report of two patients. (14396528)
1955
49
Report on treatment of obstetric Rh isoimmunization with hapten. (14381742)
1955
50
Studies in Rh-isoimmunization in pregnancy: observations in a series of 96 sensitized women. (20262969)
1947

Genetic Variations for Rh Isoimmunization

About this section

Expression for genes affiliated with Rh Isoimmunization

About this section
Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Rh Isoimmunization

Search GEO for disease gene expression data for Rh Isoimmunization.

Pathways for genes affiliated with Rh Isoimmunization

About this section

Compounds for genes affiliated with Rh Isoimmunization

About this section
Sources:
44Novoseek, 49PharmGKB, 11DrugBank, 59Tocris Bioscience, 2BitterDB, 24HMDB
See all sources

Compounds related to Rh Isoimmunization according to GeneCards/GeneDecks:

(show all 19)
idCompoundScoreTop Affiliating Genes
1succinylacetone449.8EPO, AFP
2ribavirin44 49 1111.7EPO, AFP
3vitamin b12449.7EPO, AFP
4carboplatin44 49 1111.7AFP, EPO
5bleomycin44 1110.7EPO, AFP
6phenylhydrazine449.7EPO, RHD
7thalidomide44 49 59 1112.7AFP, EPO
8mitomycin c449.6EPO, AFP
9azathioprine44 49 2 1112.6AFP, EPO
10galactose449.5AFP, RHD
11urea44 11 2411.5AFP, EPO
12latex449.4AFP, RHD
13methotrexate44 49 1111.4EPO, AFP
14sialic acid449.3AFP, EPO
15deoxyribonucleic acid449.3RHD, RHCE
16folate449.1EPO, AFP
17iron44 2410.1RHD, AFP, EPO
18aspartate449.1EPO, AFP, RHD
19oxygen44 249.8EPO, AFP, RHD

GO Terms for genes affiliated with Rh Isoimmunization

About this section
Sources:
16Gene Ontology
See all sources

Molecular functions related to Rh Isoimmunization according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1ammonium transmembrane transporter activityGO:0085199.0RHCE, RHD

Products for genes affiliated with Rh Isoimmunization

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Rh Isoimmunization

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet