MCID: RHS001
MIFTS: 27

Rh Isoimmunization malady

Category: Blood diseases

Aliases & Classifications for Rh Isoimmunization

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Aliases & Descriptions for Rh Isoimmunization:

Name: Rh Isoimmunization 11 50 39 13 68
 
Rh Incompatibility Affecting Management of Mother 11

Classifications:



External Ids:

Disease Ontology11 DOID:4175
MeSH39 D012203
NCIt45 C113150

Summaries for Rh Isoimmunization

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MalaCards based summary: Rh Isoimmunization, also known as rh incompatibility affecting management of mother, is related to retinitis pigmentosa 7 and digenic and wolff mental retardation syndrome. An important gene associated with Rh Isoimmunization is EPO (Erythropoietin). The drug rho(d) immune globulin has been mentioned in the context of this disorder. Affiliated tissues include placenta and heart.

Related Diseases for Rh Isoimmunization

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Diseases related to Rh Isoimmunization via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 49)
idRelated DiseaseScoreTop Affiliating Genes
1retinitis pigmentosa 7 and digenic10.7RHCE, RHD
2wolff mental retardation syndrome10.6RHCE, RHD
3ovary serous adenocarcinoma10.5AFP, BCL10
4postpartum depression10.5EPO, POMC
5trichuriasis10.5AFP, POMC
6cervical alveolar soft part sarcoma10.5AFP, POMC
7mohr syndrome10.4AFP, BCL10
8testicular germ cell tumor non-seminomatous10.4CSH1, CSH2
9hyperuricemia10.4AFP, ALB
10protozoal dysentery10.4ALB, NUMA1
11pineal region choriocarcinoma10.4CSH1, CSH2
12wernicke encephalopathy10.4ALB, RHCE
13splenic infarction10.4ALB, EPO
14luminal breast carcinoma10.4AFP, ALB
15parathyroid gland disease10.4AFP, ALB
16skin sarcoidosis10.3ALB, EPO
17glutathionuria10.3POMC, RHCE
18pylorus cancer10.3ALB, BCL10
19mucinous adenocarcinoma10.3AFP, BCL10
20pilar sheath acanthoma10.3CSH1, CSH2
21broad ligament malignant neoplasm10.3ALB, EPO
22contact dermatitis10.3AFP, OXT
23hemoglobinopathy10.3ALB, POMC
24autonomic peripheral neuropathy10.2RHCE, RHD
25epulis10.2AFP, CSH1, CSH2
26heart malignant hemangiopericytoma10.2AFP, CSH1, CSH2
27testicular malignant germ cell cancer10.2AFP, CSH1, CSH2
28small cell sarcoma10.2AFP, CSH1, CSH2
29intestinal disaccharidase deficiency10.1ALB, EPO, POMC
30reflex epilepsy10.1AFP, OXT
31anterior foramen magnum meningioma10.1ALB, EPO
32chronic myelomonocytic leukemia10.1ALB, EPO, POMC
33gallbladder papillomatosis10.1AFP, ALB, MSH6
34articulation disorder10.1AFP, CSH1, EPO, RHCE, RHD
35congenital epulis10.1OXT, POMC
36trachea sarcoma10.1CSH1, CSH2, MSH6
37gemistocytic astrocytoma10.1ALB, EPO, POMC
38salpingitis10.1CSH1, CSH2
39choriocarcinoma10.0CSH1, CSH2, OXT
40testicular pure germ cell tumor10.0CSH1, CSH2, OXT
41corpus luteum cyst9.9CSH1, POMC
42pyelonephritis9.9
43eclampsia9.9
44conjunctival vascular disease9.8ALB, EPO, POMC, RHCE, RHD
45toxic encephalopathy9.7CSH1, CSH2, TFPI2
46lateral sclerosis9.6CSH1, CSH2, OXT, POMC
47cervix erosion9.2AFP, CSH1, CSH2, EPHA1, OXT, PNLIP
48choroid necrotic melanoma9.2AFP, CSH1, CSH2, EPHA1, OXT, PNLIP
49pseudohypoparathyroidism5.8AFP, ALB, AMD1, BCL10, CSH1, CSH2

Graphical network of the top 20 diseases related to Rh Isoimmunization:



Diseases related to rh isoimmunization

Symptoms & Phenotypes for Rh Isoimmunization

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Drugs & Therapeutics for Rh Isoimmunization

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Interventional clinical trials:

idNameStatusNCT IDPhase
1Doppler or Amniocentesis to Predict Fetal AnemiaCompletedNCT00295516Phase 3

Search NIH Clinical Center for Rh Isoimmunization

Inferred drug relations via UMLS68/NDF-RT46:


Cochrane evidence based reviews: rh isoimmunization

Genetic Tests for Rh Isoimmunization

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Anatomical Context for Rh Isoimmunization

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MalaCards organs/tissues related to Rh Isoimmunization:

36
Placenta, Heart

Publications for Rh Isoimmunization

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Articles related to Rh Isoimmunization:

(show top 50)    (show all 91)
idTitleAuthorsYear
1
Comparison between two treatment protocols with recombinant human erythropoietin (rHuEpo) in the treatment of late anemia in neonates with Rh-isoimmunization. (23173411)
2012
2
Desferrioxamine treatment of iron overload secondary to RH isoimmunization and intrauterine transfusion in a newborn infant. (21735053)
2011
3
The effectiveness of recombinant human erythropoietin (EPO) treatment in a neonate with hyporegenerative anemia following Rh isoimmunization in spite of normal serum Epo level. (21875319)
2011
4
Recombinant human erythropoietin in the prevention of late anemia in intrauterine transfused neonates with Rh-isoimmunization. (20216236)
2010
5
Isolated early onset anemia after rh isoimmunization: a unique presentation in 3 neonates. (20628321)
2010
6
Rh isoimmunization in Sub-Saharan Africa indicates need for universal access to anti-RhD immunoglobulin and effective management of D-negative pregnancies. (21270966)
2010
7
Intraperitoneal transfusion in severe, early-onset Rh isoimmunization. (17906023)
2007
8
Noninvasive management of Rh partial null (D--) to supplement traditional management of Rh isoimmunization. (14607036)
2003
9
Ontogeny of the fetal immune system: study on pregnancies with Rh-isoimmunization and nonimmune fetal hydrops. (9884359)
1999
10
Prevention of Rh isoimmunization after spontaneous, massive fetomaternal hemorrhage. (8790318)
1996
11
Rho (D) immune globulin i.v. for prevention of Rh isoimmunization and for treatment of ITP. (8544794)
1996
12
Rh isoimmunization complicating a triplet gestation. A case report. (1906542)
1991
13
Placental transfer of cefazolin and piperacillin in pregnancies remote from term complicated by Rh isoimmunization. (2119561)
1990
14
Fetal heart rate responses to anemia in Rh isoimmunization. (2117061)
1990
15
A case of Rh isoimmunization: should threatened first-trimester abortion be an indication for Rh immune globulin prophylaxis? (2115737)
1990
16
Acute Rh isoimmunization following abdominal trauma associated with late abruption placenta. (2517184)
1989
17
Intrauterine transfusion via umbilical vein in severe Rh isoimmunization. (2499936)
1989
18
Intravascular fetal blood transfusion under ultrasonic guidance in a case of severe Rh isoimmunization. (3150641)
1988
19
Prevention of Rh isoimmunization and treatment of the compromised fetus. (3146812)
1988
20
Severe Rh isoimmunization--current methods of in utero diagnosis and treatment. (3132854)
1988
21
Umbilical cord hematoma secondary to in utero intravascular transfusion for Rh isoimmunization. (3142213)
1987
22
Fetal blood velocities in Rh isoimmunization: relationship to gestational age and to fetal hematocrit. (2942811)
1986
23
Compliance with postpartum Rh isoimmunization prophylaxis in Alberta. (2996738)
1985
24
Clinical experience with the prevention of Rh-isoimmunization: a historical comparative analysis. (6202159)
1984
25
Rh isoimmunization following abdominal trauma: a case report. (6430091)
1984
26
Circulating placental proteins in pregnancies complicated by RH isoimmunization. (6429588)
1984
27
Histopathological study of placenta in Rh isoimmunization. (6418646)
1983
28
Rh isoimmunization related to amniocentesis. (6419606)
1983
29
Pathophysiology of Rh isoimmunization. (6809383)
1982
30
Rh isoimmunization following genetic amniocentesis. (6815628)
1982
31
Rh isoimmunization: a 24 year experience at Duke University Medical Center. (6791500)
1981
32
Plasmapheresis as an adjunct to management of Rh isoimmunization. (7192839)
1981
33
RH isoimmunization. (106230)
1979
34
RH isoimmunization prevention program in a community hospital. (106231)
1979
35
Ultrasonographic diagnosis of intervillous thrombosis related to Rh isoimmunization. (119677)
1979
36
Suppression of Rh isoimmunization. A review. (101918)
1978
37
Antenatal prophylaxis of Rh isoimmunization: 28-weeks'-gestation service program. (77715)
1978
38
Rh isoimmunization during pregnancy: antenatal prophylaxis. (77714)
1978
39
The management of Rh-Isoimmunization. (98742)
1978
40
Promethazine hydrochloride: use in patients with Rh isoimmunization. (637081)
1978
41
Rh isoimmunization, Manitoba, 1963-75. (402178)
1977
42
Clinical observation of the prevention of RH isoimmunization with immunoglobulin anti-D. (4219865)
1974
43
Sex ratio in Rh incompatibility and Rh isoimmunization. (4125603)
1973
44
The clinical value of amniotic fluid analysis in pregnancies complicated by Rh-isoimmunization or hepatosis. (4631936)
1973
45
Oestriol conjugates in amniotic fluid. Qualitative and quantitative aspects, including preliminary studies in Rh isoimmunization. (4353745)
1973
46
Rh isoimmunization in ruptured pregnancy. (5083898)
1972
47
Prevention of Rh isoimmunization. (4110995)
1972
48
Plama estradiol, estriol, and progesterone in human pregnancy. II. Clinical applications in Rh-isoimmunization disease. (4628989)
1972
49
The detection of anti-Rh O antibody as part of the programme in the prevention of Rh isoimmunization in Rh-negative mothers in Australia. (4112704)
1972
50
Total protein content in amniotic fluid from normal pregnancies and from pregnancies complicated by rh-isoimmunization. (4558916)
1972

Variations for Rh Isoimmunization

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Expression for genes affiliated with Rh Isoimmunization

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Search GEO for disease gene expression data for Rh Isoimmunization.

Pathways for genes affiliated with Rh Isoimmunization

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GO Terms for genes affiliated with Rh Isoimmunization

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Biological processes related to Rh Isoimmunization according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1ammonium transmembrane transportGO:007248810.5RHCE, RHD
2nitrogen utilizationGO:001974010.5RHCE, RHD
3organic cation transportGO:001569510.5RHCE, RHD
4response to electrical stimulusGO:005160210.1EPO, OXT
5response to foodGO:00320949.7BCL10, OXT

Molecular functions related to Rh Isoimmunization according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1ammonium transmembrane transporter activityGO:000851910.4RHCE, RHD
2neuropeptide hormone activityGO:00051849.5OXT, POMC

Sources for Rh Isoimmunization

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet