MCID: RHS001
MIFTS: 35

Rh Isoimmunization malady

Summaries for Rh Isoimmunization

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63Wikipedia, 32MalaCards
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Wikipedia:63 Rh disease (also known as Rhesus isoimmunisation, Rh (D) disease, Rhesus incompatibility, Rhesus... more...

MalaCards: Rh Isoimmunization, also known as rh incompatibility affecting management of mother, is related to neonatal anemia and fetal erythroblastosis. An important gene associated with Rh Isoimmunization is EPO (erythropoietin). The drug rho(d) immune globulin and the compounds succinylacetone and ribavirin have been mentioned in the context of this disorder. Affiliated tissues include placenta and heart.

Aliases & Classifications for Rh Isoimmunization

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8Disease Ontology, 10DISEASES, 44Novoseek, 60UMLS, 56SNOMED-CT, 34MeSH
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Aliases & Descriptions:

rh isoimmunization 8 10 44 60
rh incompatibility affecting management of mother 8
rhesus isoimmunization affecting pregnancy 8
rhesus isoimmunisation in pregnancy 8
rhesus isoimmunization unspecified 8
rhesus isoimmunization nos 8
rhesus isoimmunisation 8


External Ids:

Disease Ontology8 DOID:4175
MeSH34 D012203

Related Diseases for Rh Isoimmunization

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Rh Isoimmunization:



Diseases related to rh isoimmunization

Clinical Features for Rh Isoimmunization

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Drugs & Therapeutics for Rh Isoimmunization

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

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Drug clinical trials:

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Search CenterWatch for Rh Isoimmunization

Inferred drug relations via UMLS60/NDF-RT40:

Genetic Tests for Rh Isoimmunization

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Anatomical Context for Rh Isoimmunization

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32MalaCards
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MalaCards organs/tissues related to Rh Isoimmunization:

32
Placenta, Heart

Animal Models for Rh Isoimmunization or affiliated genes

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Publications for Rh Isoimmunization

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50PubMed
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Articles related to Rh Isoimmunization:

(show top 50)    (show all 91)
idTitleAuthorsYear
1
Desferrioxamine treatment of iron overload secondary to RH isoimmunization and intrauterine transfusion in a newborn infant. (21735053)
2011
2
Recombinant human erythropoietin in the prevention of late anemia in intrauterine transfused neonates with Rh-isoimmunization. (20216236)
2010
3
Intraperitoneal transfusion in severe, early-onset Rh isoimmunization. (17906023)
2007
4
Noninvasive management of Rh partial null (D--) to supplement traditional management of Rh isoimmunization. (14607036)
2003
5
Rho (D) immune globulin i.v. for prevention of Rh isoimmunization and for treatment of ITP. (8544794)
1996
6
Rh isoimmunization complicating a triplet gestation. A case report. (1906542)
1991
7
A case of Rh isoimmunization: should threatened first-trimester abortion be an indication for Rh immune globulin prophylaxis? (2115737)
1990
8
Fetal heart rate responses to anemia in Rh isoimmunization. (2117061)
1990
9
Intrauterine transfusion via umbilical vein in severe Rh isoimmunization. (2499936)
1989
10
Intravascular fetal blood transfusion under ultrasonic guidance in a case of severe Rh isoimmunization. (3150641)
1988
11
Severe Rh isoimmunization--current methods of in utero diagnosis and treatment. (3132854)
1988
12
Umbilical cord hematoma secondary to in utero intravascular transfusion for Rh isoimmunization. (3142213)
1987
13
Compliance with postpartum Rh isoimmunization prophylaxis in Alberta. (2996738)
1985
14
Rh isoimmunization following abdominal trauma: a case report. (6430091)
1984
15
Histopathological study of placenta in Rh isoimmunization. (6418646)
1983
16
Pathophysiology of Rh isoimmunization. (6809383)
1982
17
RH isoimmunization. (106230)
1979
18
Ultrasonographic diagnosis of intervillous thrombosis related to Rh isoimmunization. (119677)
1979
19
Rh isoimmunization during pregnancy: antenatal prophylaxis. (77714)
1978
20
Suppression of Rh isoimmunization. A review. (101918)
1978
21
Promethazine hydrochloride: use in patients with Rh isoimmunization. (637081)
1978
22
Antenatal prophylaxis of Rh isoimmunization: 28-weeks'-gestation service program. (77715)
1978
23
Rh isoimmunization, Manitoba, 1963-75. (402178)
1977
24
Sex ratio in Rh incompatibility and Rh isoimmunization. (4125603)
1973
25
The clinical value of amniotic fluid analysis in pregnancies complicated by Rh-isoimmunization or hepatosis. (4631936)
1973
26
Plama estradiol, estriol, and progesterone in human pregnancy. II. Clinical applications in Rh-isoimmunization disease. (4628989)
1972
27
The detection of anti-Rh O antibody as part of the programme in the prevention of Rh isoimmunization in Rh-negative mothers in Australia. (4112704)
1972
28
Prevention of Rh isoimmunization. (4110995)
1972
29
The risk of Rh isoimmunization in ruptured tubal pregnancy. (4631183)
1972
30
Estriol conjugates in amniotic fluid in normal pregnancies and Rh-isoimmunization. (4330538)
1970
31
Haemolytic disease of the newborn due to Rh-isoimmunization: the role of free anti-D antibodies in bilirubin rebound. (5004392)
1970
32
Some epidemiological aspects of the prevention of Rh isoimmunization. (5003520)
1970
33
High-titer anti-D plasma for the prevention of Rh isoimmunization. (4988960)
1970
34
Rh haemolytic disease. Recent advances in Rh isoimmunization prevention. (4192020)
1970
35
Fetal transfusion in severe Rh isoimmunization. Indications, efficiency, and results based on 218 transfusions carried out on 100 fetuses. (4974316)
1969
36
Free anti-D antibody in haemolytic disease of the newborn due to Rh-isoimmunization. (5393080)
1969
37
Prevention of Rh isoimmunization. (4973031)
1968
38
Antibodies of Rh isoimmunization. (4193259)
1968
39
Rh isoimmunization: its incidence, timing, and relationship to fetal-maternal hemorrhage. (4961378)
1967
40
Changing concepts in Rh isoimmunization. (4953693)
1965
41
Recent trends in the management of Rh isoimmunization. (4954782)
1965
42
PSEUDOTOXEMIC STATE ASSOCIATED WITH SEVERE RH ISOIMMUNIZATION. (14155011)
1964
43
CURRENT COMCEPTS IN THE MANAGEMENT OF THE PREGNANCY COMPLICATED BY RH ISOIMMUNIZATION. (14076474)
1963
44
Urinary estriol excretion of pregnant patients with pyelonephritis and Rh isoimmunization. (13993577)
1963
45
Effect of ABO incompatibility on Rh isoimmunization. (14031839)
1963
46
Eclampsia at the sixteenth week of gestation with Rh isoimmunization and cystic degeneration of the placenta. (13833198)
1960
47
The Protective Action of ABO Incompatibility on Rh Isoimmunization and Rh Hemolytic Disease-Theoretical and Clinical Implications. (17948444)
1959
48
Haemolytic disease of the newborn due to Rh isoimmunization; a ten-year review with emphasis on exchange transfusion. (13472561)
1957
49
Some obstetric factors in Rh isoimmunization. (13313607)
1956
50
The use of corticotropin in Rh isoimmunization. (13122459)
1953

Genetic Variations for Rh Isoimmunization

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Expression for genes affiliated with Rh Isoimmunization

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Rh Isoimmunization

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Pathways for genes affiliated with Rh Isoimmunization

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Compounds for genes affiliated with Rh Isoimmunization

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44Novoseek, 49PharmGKB, 11DrugBank, 59Tocris Bioscience, 2BitterDB, 24HMDB
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Compounds related to Rh Isoimmunization according to GeneCards/GeneDecks:

(show all 19)
idCompoundScoreTop Affiliating Genes
1succinylacetone449.8EPO, AFP
2ribavirin44 49 1111.7EPO, AFP
3vitamin b12449.7EPO, AFP
4carboplatin44 49 1111.7AFP, EPO
5bleomycin44 1110.7EPO, AFP
6phenylhydrazine449.7EPO, RHD
7thalidomide44 49 59 1112.7AFP, EPO
8mitomycin c449.6EPO, AFP
9azathioprine44 49 2 1112.6AFP, EPO
10galactose449.5AFP, RHD
11urea44 11 2411.5AFP, EPO
12latex449.4AFP, RHD
13methotrexate44 49 1111.4EPO, AFP
14sialic acid449.3AFP, EPO
15deoxyribonucleic acid449.3RHD, RHCE
16folate449.1EPO, AFP
17iron44 2410.1RHD, AFP, EPO
18aspartate449.1EPO, AFP, RHD
19oxygen44 249.8EPO, AFP, RHD

GO Terms for genes affiliated with Rh Isoimmunization

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16Gene Ontology
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Molecular functions related to Rh Isoimmunization according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1ammonium transmembrane transporter activityGO:0085199.0RHCE, RHD

Products for genes affiliated with Rh Isoimmunization

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Rh Isoimmunization

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet