MCID: RHS001
MIFTS: 30

Rh Isoimmunization malady

Category: Blood diseases

Aliases & Classifications for Rh Isoimmunization

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Aliases & Descriptions for Rh Isoimmunization:

Name: Rh Isoimmunization 10 47 12 36 65
 
Rh Incompatibility Affecting Management of Mother 10

Classifications:



External Ids:

Disease Ontology10 DOID:4175
MeSH36 D012203
NCIt42 C113150
UMLS65 C0035404

Summaries for Rh Isoimmunization

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MalaCards based summary: Rh Isoimmunization, also known as rh incompatibility affecting management of mother, is related to atherosclerosis and arterial calcification of infancy. An important gene associated with Rh Isoimmunization is EPO (Erythropoietin), and among its related pathways is FOXA2 and FOXA3 transcription factor networks. The drug rho(d) immune globulin has been mentioned in the context of this disorder. Affiliated tissues include heart, neutrophil and prostate.

Related Diseases for Rh Isoimmunization

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Diseases related to Rh Isoimmunization via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 135)
idRelated DiseaseScoreTop Affiliating Genes
1atherosclerosis30.5EPHA1, EPO, OXT
2arterial calcification of infancy10.5RHCE, RHD
3appendix lymphoma10.5RHCE, RHD
4breast cancer10.5
5endotheliitis10.5
6acinic cell breast carcinoma10.5AFP, BCL10
7autoimmune disease of cardiovascular system10.4RHCE, RHD
8chromosome 1, uniparental disomy 1q12 q2110.4AFP, BCL10
9b cell deficiency10.4RHCE, RHD
10breast mucinous cystadenocarcinoma10.4RHCE, RHD
11granulomatous dermatitis10.4RHCE, RHD
12toxic maculopathy10.4EPO, POMC
13retinal perforation10.4AFP, POMC
14colon mucinous adenocarcinoma10.4AFP, BCL10
15ovarian cystic teratoma10.4AFP, POMC
16somatoform disorder10.4ALB, EPO
17leukemia10.4
18gingivitis10.4
19pancreatitis10.4
20hypoxia10.4
21seminoma10.4AFP, POMC
22nephronophthisis familial adult spastic quadriparesis10.3ALB, EPO
23angioid streaks10.3ALB, EPO
24diffuse meningeal melanocytosis10.3ALB, EPO
25t cell deficiency10.3AFP, ALB
26microinvasive gastric cancer10.3ALB, BCL10
27cerebral lipidosis10.3ALB, EPO
28irritant dermatitis10.3AFP, OXT
29acrodermatitis10.3AFP, ALB
30bipolar ll disorder10.3POMC, RHCE, RHD
31diplegia of upper limb10.2POMC, RHCE, RHD
32extratemporal epilepsy10.2AFP, OXT
33hemoglobin c disease10.2ALB, POMC
34adult endodermal sinus tumor10.2AFP, ALB
35syngap1-related non-syndromic intellectual disability10.2ALB, POMC
36colorectal cancer10.2
37melioidosis10.2
38obesity10.2
39alkaptonuria10.2
40renal cell carcinoma10.2
41insulin-like growth factor i10.2
42tyrosinemia, type ii10.2
43neurofibromatosis, type 110.2
44peripheral vascular disease10.2
45acute leukemia10.2
46arthritis10.2
47cataract10.2
48charcot-marie-tooth disease10.2
49glycogen storage disease10.2
50hepatitis10.2

Graphical network of the top 20 diseases related to Rh Isoimmunization:



Diseases related to rh isoimmunization

Symptoms for Rh Isoimmunization

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Drugs & Therapeutics for Rh Isoimmunization

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Interventional clinical trials:

idNameStatusNCT IDPhase
1Doppler or Amniocentesis to Predict Fetal AnemiaCompletedNCT00295516Phase 3

Search NIH Clinical Center for Rh Isoimmunization

Inferred drug relations via UMLS65/NDF-RT43:


Cochrane evidence based reviews: rh isoimmunization

Genetic Tests for Rh Isoimmunization

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Anatomical Context for Rh Isoimmunization

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MalaCards organs/tissues related to Rh Isoimmunization:

33
Heart, Neutrophil, Prostate, Myeloid, Lung, B cells, Nk cells

Animal Models for Rh Isoimmunization or affiliated genes

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Publications for Rh Isoimmunization

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Articles related to Rh Isoimmunization:

(show top 50)    (show all 91)
idTitleAuthorsYear
1
The Smad3/Smad4/CDK9 complex promotes renal fibrosis in mice with unilateral ureteral obstruction. (26221756)
2015
2
Navigated trancranial magnetic stimulation in amyotrophic lateral sclerosis. (25388001)
2014
3
An unusual cause of optic atrophy in a child. (24817753)
2014
4
Intermediate conformation between native I^-sheet and non-native I+-helix is a precursor of trifluoroethanol-induced aggregation of human carbonic anhydrase-II. (24813993)
2014
5
E23K variant in KCNJ11 gene is associated with susceptibility to type 2 diabetes in the Mauritanian population. (24332549)
2014
6
Hypothetical pathogenesis of eosinophilic infiltration in Langerhans cell histiocytosis of the jaw. (23773614)
2013
7
Cathelicidin, kallikrein 5, and serine protease activityA is inhibited during treatment of rosacea with azelaic acid 15% gel. (23871720)
2013
8
Genetic variation in IL18R1 and IL18 genes and Inteferon I^ ELISPOT response to smallpox vaccination: an unexpected relationship. (23901078)
2013
9
Endosonography and elastography in the diagnosis of esophageal tuberculosis. (24226724)
2013
10
Pancreatic tumors and immature immunosuppressive myeloid cells in blood and spleen: role of inhibitory co-stimulatory molecules PDL1 and CTLA4. An in vivo and in vitro study. (23359812)
2013
11
Post-traumatic sagittal sinus thrombosis: case report. (23588984)
2013
12
Coexistence of patch stage mycosis fungoides and interstitial granuloma annulare in the same patient: a pitfall in the clinicopathologic diagnosis of mycosis fungoides. (22240773)
2012
13
Chemical-genetic analysis of cyclin dependent kinase 2 function reveals an important role in cellular transformation by multiple oncogenic pathways. (22474407)
2012
14
Loss of I+T-catenin alters the hybrid adhering junctions in the heart and leads to dilated cardiomyopathy and ventricular arrhythmia following acute ischemia. (22421363)
2012
15
Switching of anti-TNF-I+ agents in BehAset's disease. (23010387)
2012
16
Difference in angiotensinogen haplotype frequencies between chronic heart failure and advanced atherosclerosis patients - new prognostic factor? (20945963)
2011
17
A patient with a dysembryoplastic neuroepithelial tumor who underwent epilepsy surgery after initial seizure. (22777137)
2011
18
CD133 expression is associated with small round blue cell tumour morphology in human central nervous system neoplasms. (21438906)
2011
19
A unique BCR-ABL1 transcript with the insertion of intronic sequence from BCR and ABL1 genes in a patient with Philadelphia-positive chronic myeloid leukemia: a case study. (20633771)
2010
20
Effect of shenshao tablet on the quality of life for coronary heart disease patients with stable angina pectoris. (19802534)
2009
21
Mutations in the melanocortin 4 receptor (MC4R) gene in obese patients in Norway. (19301229)
2009
22
Optic neuritis and recurrent myelitis in a woman with systemic lupus erythematosus. (18493269)
2008
23
Roles for loop 2 residues of alpha1 glycine receptors in agonist activation. (18658152)
2008
24
Altered expression of genes regulating angiogenesis in experimental androgen-independent prostate cancer. (18076023)
2008
25
Depolarization recruits DCC to the plasma membrane of embryonic cortical neurons and enhances axon extension in response to netrin-1. (18691385)
2008
26
Reduced Foxp3 expression with increased cytomegalovirus-specific CTL in HTLV-I-associated myelopathy. (18639344)
2008
27
Sphingosine-induced apoptosis in rhabdomyosarcoma cell lines is dependent on pre-mitochondrial Bax activation and post-mitochondrial caspases. (17234787)
2007
28
A potent cytotoxic photoactivated platinum complex. (18093923)
2007
29
Expression of the insulin-like peptide 3 (INSL3) hormone-receptor (LGR8) system in the testis. (16467492)
2006
30
Acquired von Willebrand syndrome: features and management. (16823821)
2006
31
p21-activated kinase (Pak) regulates NADPH oxidase activation in human neutrophils. (16099876)
2005
32
Actinomycosis of the knee. (22605950)
2005
33
Efficacy of multidrug therapy combined with mizoribine in children with diffuse IgA nephropathy in comparison with multidrug therapy without mizoribine and with methylprednisolone pulse therapy. (15550753)
2004
34
Acrokeratosis paraneoplastica associated with recurrent metastatic thymic carcinoma. (15245552)
2004
35
Evidence for a role for Galphai1 in mediating weak agonist-induced platelet aggregation in human platelets: reduced Galphai1 expression and defective Gi signaling in the platelets of a patient with a chronic bleeding disorder. (12609843)
2003
36
A single base alteration in the CGG repeat region of FMR1: possible effects on gene expression and phenotype. (11897823)
2002
37
Crystallization and preliminary crystallographic characterization of the extracellular Ig-like domain of human natural killer cell activating receptor NKp44. (12351833)
2002
38
Dedifferentiated liposarcoma of the cheek: case report and literature review. (12019743)
2002
39
Sudden infant death syndrome, bedsharing, parental weight, and age at death. (11230594)
2001
40
The pravastatin inflammation CRP evaluation (PRINCE): rationale and design. (11376301)
2001
41
Osteopontin is expressed by adult human osteoarthritic chondrocytes: protein and mRNA analysis of normal and osteoarthritic cartilage. (10936449)
2000
42
Reelin is a ligand for lipoprotein receptors. (10571240)
1999
43
Tumor necrosis factor-related apoptosis-inducing ligand receptors signal NF-kappaB and JNK activation and apoptosis through distinct pathways. (10521444)
1999
44
Immediate sexual rehabilitation by simultaneous placement of penile prosthesis in patients undergoing radical prostatectomy: initial results in 50 patients. (9301704)
1997
45
Assignment of the human gene for Oct-binding factor-1 (OBF1), a B-cell-specific coactivator of octamer-binding transcription factors 1 and 2, to 11q23.1 by somatic cell hybridization and in situ hybridization. (8617501)
1996
46
Transfection of pancreatic acinar cells (AR4-2J) by bFGF modifies cell morphology and biosynthesis of pancreatic secretory enzymes]. (1385247)
1992
47
Unilateral cerebellar hypoplasia. (1606782)
1992
48
16-kilodalton heparin binding (fibroblast) growth factor type one appears in a stable 40-kilodalton complex after receptor-dependent internalization. (2005115)
1991
49
Adrenogenital syndrome due to 11-beta-hydroxylase deficiency with skeletal abnormalities and pulmonary stenosis. (6609951)
1984
50
Acid secretion in symptomatic sliding hiatus hernia. (4163124)
1967

Variations for Rh Isoimmunization

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Expression for genes affiliated with Rh Isoimmunization

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Search GEO for disease gene expression data for Rh Isoimmunization.

Pathways for genes affiliated with Rh Isoimmunization

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Pathways related to Rh Isoimmunization according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.2AFP, ALB, PSG1

GO Terms for genes affiliated with Rh Isoimmunization

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Biological processes related to Rh Isoimmunization according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1nitrogen utilizationGO:001974010.1RHCE, RHD
2ammonium transmembrane transportGO:007248810.0RHCE, RHD
3organic cation transportGO:001569510.0RHCE, RHD

Sources for Rh Isoimmunization

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet