MCID: RHS001
MIFTS: 33

Rh Isoimmunization malady

Blood diseases category

Summaries for Rh Isoimmunization

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66Wikipedia, 34MalaCards
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Wikipedia:66 Rh disease (also known as Rhesus isoimmunisation, Rh (D) disease, Rhesus incompatibility, Rhesus... more...

MalaCards: Rh Isoimmunization, also known as rh incompatibility affecting management of mother, is related to fetal erythroblastosis and eclampsia. An important gene associated with Rh Isoimmunization is EPO (erythropoietin). The drug rho(d) immune globulin and the compounds phenylhydrazine and oxygen have been mentioned in the context of this disorder. Affiliated tissues include placenta and heart.

Aliases & Classifications for Rh Isoimmunization

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9Disease Ontology, 11DISEASES, 46Novoseek, 63UMLS, 59SNOMED-CT, 36MeSH
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Blood diseases


Aliases & Descriptions:

rh isoimmunization 9 11 46 63
rh incompatibility affecting management of mother 9
rhesus isoimmunization affecting pregnancy 9
rhesus isoimmunisation in pregnancy 9
rhesus isoimmunization unspecified 9
rhesus isoimmunization nos 9
rhesus isoimmunisation 9


External Ids:

Disease Ontology9 DOID:4175
MeSH36 D012203

Related Diseases for Rh Isoimmunization

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Sources:
18GeneCards, 19GeneDecks
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Diseases related to Rh Isoimmunization via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 13)
idRelated DiseaseScoreTop Affiliating Genes
1fetal erythroblastosis10.4
2eclampsia10.2
3pyelonephritis10.2
4malaria10.0RHD
5beta thalassemia10.0EPO, RHD
6sickle cell disease10.0RHD, EPO
7hemolytic anemia10.0RHD, EPO
8uremia10.0RHD, EPO
9kernicterus10.0RHD, RHCE
10factor v leiden thrombophilia10.0RHD, EPO
11myeloma10.0EPO, RHD
12chronic kidney failure10.0RHD, EPO
13deficiency anemia9.9RHCE, RHD, EPO

Graphical network of diseases related to Rh Isoimmunization:



Diseases related to rh isoimmunization

Symptoms for Rh Isoimmunization

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Drugs & Therapeutics for Rh Isoimmunization

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 63UMLS, 42NDF-RT
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Approved drugs:

Search CenterWatch for Rh Isoimmunization

Drug clinical trials:

Search ClinicalTrials for Rh Isoimmunization

Search NIH Clinical Center for Rh Isoimmunization

Search CenterWatch for Rh Isoimmunization

Inferred drug relations via UMLS63/NDF-RT42:

Genetic Tests for Rh Isoimmunization

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Anatomical Context for Rh Isoimmunization

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34MalaCards
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MalaCards organs/tissues related to Rh Isoimmunization:

34
Placenta, Heart

Animal Models for Rh Isoimmunization or affiliated genes

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Publications for Rh Isoimmunization

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53PubMed
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Articles related to Rh Isoimmunization:

(show top 50)    (show all 91)
idTitleAuthorsYear
1
Recombinant human erythropoietin in the prevention of late anemia in intrauterine transfused neonates with Rh-isoimmunization. (20216236)
2010
2
Intraperitoneal transfusion in severe, early-onset Rh isoimmunization. (17906023)
2007
3
Noninvasive management of Rh partial null (D--) to supplement traditional management of Rh isoimmunization. (14607036)
2003
4
Ontogeny of the fetal immune system: study on pregnancies with Rh-isoimmunization and nonimmune fetal hydrops. (9884359)
1999
5
Prevention of Rh isoimmunization after spontaneous, massive fetomaternal hemorrhage. (8790318)
1996
6
Rh isoimmunization complicating a triplet gestation. A case report. (1906542)
1991
7
Placental transfer of cefazolin and piperacillin in pregnancies remote from term complicated by Rh isoimmunization. (2119561)
1990
8
Acute Rh isoimmunization following abdominal trauma associated with late abruption placenta. (2517184)
1989
9
Intravascular fetal blood transfusion under ultrasonic guidance in a case of severe Rh isoimmunization. (3150641)
1988
10
Prevention of Rh isoimmunization and treatment of the compromised fetus. (3146812)
1988
11
Umbilical cord hematoma secondary to in utero intravascular transfusion for Rh isoimmunization. (3142213)
1987
12
Fetal blood velocities in Rh isoimmunization: relationship to gestational age and to fetal hematocrit. (2942811)
1986
13
Circulating placental proteins in pregnancies complicated by RH isoimmunization. (6429588)
1984
14
Clinical experience with the prevention of Rh-isoimmunization: a historical comparative analysis. (6202159)
1984
15
Rh isoimmunization following abdominal trauma: a case report. (6430091)
1984
16
Pathophysiology of Rh isoimmunization. (6809383)
1982
17
Rh isoimmunization: a 24 year experience at Duke University Medical Center. (6791500)
1981
18
Plasmapheresis as an adjunct to management of Rh isoimmunization. (7192839)
1981
19
RH isoimmunization. (106230)
1979
20
Rh isoimmunization during pregnancy: antenatal prophylaxis. (77714)
1978
21
The management of Rh-Isoimmunization. (98742)
1978
22
Rh isoimmunization, Manitoba, 1963-75. (402178)
1977
23
Sex ratio in Rh incompatibility and Rh isoimmunization. (4125603)
1973
24
Oestriol conjugates in amniotic fluid. Qualitative and quantitative aspects, including preliminary studies in Rh isoimmunization. (4353745)
1973
25
The clinical value of amniotic fluid analysis in pregnancies complicated by Rh-isoimmunization or hepatosis. (4631936)
1973
26
Plama estradiol, estriol, and progesterone in human pregnancy. II. Clinical applications in Rh-isoimmunization disease. (4628989)
1972
27
The detection of anti-Rh O antibody as part of the programme in the prevention of Rh isoimmunization in Rh-negative mothers in Australia. (4112704)
1972
28
Total protein content in amniotic fluid from normal pregnancies and from pregnancies complicated by rh-isoimmunization. (4558916)
1972
29
Rh isoimmunization in ruptured pregnancy. (5083898)
1972
30
Significance of mid-zone fluctuations in amniotic fluid spectrophotometric analysis for Rh-isoimmunization. (5416701)
1970
31
Estriol conjugates in amniotic fluid in normal pregnancies and Rh-isoimmunization. (4330538)
1970
32
Haemolytic disease of the newborn due to Rh-isoimmunization: the role of free anti-D antibodies in bilirubin rebound. (5004392)
1970
33
Some epidemiological aspects of the prevention of Rh isoimmunization. (5003520)
1970
34
High-titer anti-D plasma for the prevention of Rh isoimmunization. (4988960)
1970
35
Rh haemolytic disease. Recent advances in Rh isoimmunization prevention. (4192020)
1970
36
Fetal transfusion in severe Rh isoimmunization. Indications, efficiency, and results based on 218 transfusions carried out on 100 fetuses. (4974316)
1969
37
Management of patients with Rh isoimmunization based on amniotic fluid examination. (5766484)
1969
38
Prevention of Rh isoimmunization. (4973031)
1968
39
Prevention of Rh isoimmunization. Progress report of the clinical trial in mothers. (4163377)
1967
40
Prevention of Rh isoimmunization by injection of anti-D antibody. (6061830)
1967
41
Intrauterine transfusion in Rh-isoimmunization. (6059275)
1967
42
Changing concepts in Rh isoimmunization. (4953693)
1965
43
PSEUDOTOXEMIC STATE ASSOCIATED WITH SEVERE RH ISOIMMUNIZATION. (14155011)
1964
44
CURRENT COMCEPTS IN THE MANAGEMENT OF THE PREGNANCY COMPLICATED BY RH ISOIMMUNIZATION. (14076474)
1963
45
The protective action of ABO incompatibility on Rh isoimmunization and Rh hemolytic disease; theoretical and clinical implications. (13641945)
1959
46
Some obstetric factors in Rh isoimmunization. (13313607)
1956
47
RH isoimmunization associated with regurgitation jaundice beginning in utero; report of two patients. (14396528)
1955
48
Report on treatment of obstetric Rh isoimmunization with hapten. (14381742)
1955
49
The use of corticotropin in Rh isoimmunization. (13122459)
1953
50
Does Rh-isoimmunization cause early abortion? (20257308)
1947

Variations for Rh Isoimmunization

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Expression for genes affiliated with Rh Isoimmunization

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Rh Isoimmunization

Search GEO for disease gene expression data for Rh Isoimmunization.

Pathways for genes affiliated with Rh Isoimmunization

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Compounds for genes affiliated with Rh Isoimmunization

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46Novoseek, 25HMDB
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Compounds related to Rh Isoimmunization according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1phenylhydrazine469.4EPO, RHD
2oxygen46 2510.3EPO, RHD
3iron46 2510.2RHD, EPO
4deoxyribonucleic acid469.1RHD, RHCE
5aspartate469.0EPO, RHD

GO Terms for genes affiliated with Rh Isoimmunization

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17Gene Ontology
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Molecular functions related to Rh Isoimmunization according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1ammonium transmembrane transporter activityGO:0085199.1RHCE, RHD

Products for genes affiliated with Rh Isoimmunization

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Rh Isoimmunization

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet