MCID: RHM001
MIFTS: 50

Rheumatic Fever malady

Categories: Rare diseases, Cardiovascular diseases

Aliases & Classifications for Rheumatic Fever

About this section

Aliases & Descriptions for Rheumatic Fever:

Name: Rheumatic Fever 11 48 50 39 13 68
Acute Rheumatic Fever 11 48 50
 
Inflammatory Rheumatism 48
Rhf - Rheumatic Fever 11

Classifications:



Summaries for Rheumatic Fever

About this section
NIH Rare Diseases:48 Rheumatic fever is an inflammatory condition that may develop after infection with group A Streptococcus bacteria, such as strep throat or scarlet fever. It is primarily diagnosed in children between the ages of 6 and 16 and can affect the heart, joints, nervous system and/or skin. Early signs and symptoms include sore throat; swollen red tonsils; fever; headache; and/or muscle and joint aches. Some affected people develop rheumatic heart disease, which can lead to serious inflammation and scarring of the heart valves. It is not clear why some people who are infected with group A Streptococcus bacteria go on to develop rheumatic fever, while others do not; however, it appears that some families may have a genetic susceptibility to develop the condition. Treatment usually includes antibiotics and/or anti-inflammatory medications. Last updated: 1/11/2015

MalaCards based summary: Rheumatic Fever, also known as acute rheumatic fever, is related to pharyngitis and kernicterus, and has symptoms including osler's node and pathergy reaction. An important gene associated with Rheumatic Fever is MYOM2 (Myomesin 2), and among its related pathways are Malaria and IgA-Producing B Cells in the Intestine. The drugs aspirin and choline salicylate have been mentioned in the context of this disorder. Affiliated tissues include heart, skin and brain, and related mouse phenotype immune system.

Wikipedia:71 Rheumatic fever (RF), also known as acute rheumatic fever (ARF), is an inflammatory disease that can... more...

Related Diseases for Rheumatic Fever

About this section

Diseases related to Rheumatic Fever via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 238)
idRelated DiseaseScoreTop Affiliating Genes
1pharyngitis30.7IL2, MBL2
2kernicterus29.9HLA-DRB1, IL2, TNF
3gastric ulcer29.7IL2, TLR2, TNF
4rheumatoid arthritis29.0CD40LG, HLA-DRB1, IL2, TLR2, TNF
5systemic lupus erythematosus28.5CD40LG, FCN3, HLA-DRB1, IL2, MBL2, TNF
6rheumatic fever-related antigen rheumatic fever, acute, susceptibility to, included12.3
7rheumatic myocarditis11.5
8acute articular rheumatism11.2
9aortic valve disease 210.9
10common variable immunodeficiency10.7HLA-DRB1, TNF
11parsonage turner syndrome10.7HLA-DRB1, TNF
12weber syndrome10.7HLA-DRB1, TNF
13myopathy-growth delay-intellectual disability-hypospadias syndrome10.7HLA-DRB1, TNF
14krieble bixler syndrome10.6HLA-DRB1, TNF
15rhizomelic pseudopolyarthritis10.6HLA-DRB1, TNF
16epstein-barr virus hepatitis10.6HLA-DRB1, TNF
17abdominal chemodectomas with cutaneous angiolipomas10.6HLA-DRB1, TNF
18warm antibody hemolytic anemia10.6MBL2, TNF
19autoimmune polyendocrine syndrome10.6MYOM2, TNF
20linitis plastica10.6IL2, TNF
21lymphocytic colitis10.6HLA-DRB1, TNF
22panuveitis10.6HLA-DRB1, TNF
23spastic paraplegia-paget disease of bone syndrome10.6HLA-DRB1, TNF
24peripheral t-cell lymphoma10.6HLA-DRB1, TNF
25heart disease10.6
26graft-versus-host disease, protection against10.6IL2, TNF
27meesmann corneal dystrophy10.6MASP2, MBL2
28hernia of ovary and fallopian tube10.6HLA-DRB1, TNF
29vitreoretinochoroidopathy dominant10.6HLA-DRB1, IL2
30rheumatic heart disease10.6
31anthracosilicosis10.6HLA-DRB1, IL2
32addison's disease10.5IL2, TNF
33sydenham chorea10.5
34solitary osseous plasmacytoma10.5IL2, MYOM2
35arachnoiditis10.5HLA-DRB1, TNF
36antigen-peptide-transporter 2 deficiency10.5TLR2, TNF
373-alpha hydroxyacyl-coa dehydrogenase deficiency10.5TLR2, TNF
38idiopathic central precocious puberty10.5HLA-DRB1, TNF
39atrial septal defect coronary sinus10.5MBL2, TLR2
40night blindness10.5CD40LG, TNF
41t-cell lymphoma 1a10.5TLR2, TNF
42cauda equina syndrome10.5MBL2, TNF
43sensorineural hearing loss10.5HLA-DRB1, TNF
44bone cancer10.5CD40LG, MYOM2
45rete ovarii cystadenoma10.5CD40LG, MYOM2
46calcinosis10.5CD40LG, MYOM2
47ileocolitis10.5CD40LG, TNF
48trichosporonosis10.5TLR2, TNF
49scleral disease10.5CD40LG, TNF
50neurofibroma of the esophagus10.4IL2, MYOM2

Graphical network of the top 20 diseases related to Rheumatic Fever:



Diseases related to rheumatic fever

Symptoms & Phenotypes for Rheumatic Fever

About this section

UMLS symptoms related to Rheumatic Fever:


osler's node, pathergy reaction

MGI Mouse Phenotypes related to Rheumatic Fever according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053877.0CD40LG, FCN1, HP, IL2, MASP2, MBL2

Drugs & Therapeutics for Rheumatic Fever

About this section

Drugs for Rheumatic Fever (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 101)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1Liver ExtractsPhase 43868
2
MethotrexateapprovedPhase 315181959-05-2, 59-05-2126941
Synonyms:
4-amino-10-methylfolic acid
4-amino-N(10)-Methylpteroylglutamic acid
Abitrexate
Amethopterin
Amethopterine
Antifolan
Arbitrexate
Emtexate
Folex
HDMTX
L-Amethopterin
Ledertrexate
MTX
Metatrexan
 
Methopterin
Methotextrate
Methotrate
Methotrexat
Methotrexate Sodium
Methotrexatum
Methylaminopterin
Methylaminopterinum
Metotrexato
Mexate
Méthotrexate
N-Bismethylpteroylglutamic Acid
N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid
Rheumatrex
Trexall
3
InfliximabapprovedPhase 3378170277-31-3
Synonyms:
 
Ig gamma-1 chain C region
Remicade
4
Etanerceptapproved, investigationalPhase 3397185243-69-0
Synonyms:
185243-69-0
CD120b
D00742
Enbrel
Enbrel (TN)
Enbrel Sureclick
Etanercept
Etanercept (USAN/INN)
 
Etanercept (genetical recombination)
Etanercept (genetical recombination) (JAN)
TNF-R2
Tumor necrosis factor receptor 2
Tumor necrosis factor receptor superfamily member 1B precursor
Tumor necrosis factor receptor type II
etanercept
p75
p80 TNF-alpha receptor
5
Aspirinapproved, vet_approvedPhase 3111250-78-22244
Synonyms:
11126-35-5
11126-37-7
1oxr
2-(ACETYLOXY)benzoic acid
2-(Acetyloxy)benzoate
2-(Acetyloxy)benzoic acid
2-Acetoxybenzenecarboxylic acid
2-Acetoxybenzoate
2-Acetoxybenzoic acid
2-Carboxyphenyl acetate
2349-94-2
26914-13-6
50-78-2
8-hour Bayer
98201-60-6
A 5376
A.S.A
A.S.A.
A.S.A. Empirin
A.S.A. empirin
A2093_SIGMA
A3160_SIGMA
A5376_SIGMA
A6810_SIGMA
AB1003266
AC 5230
AC1L1D8U
AC1Q1LA0
ACETYLSALICYLIC ACID
AI3-02956
AIN
AKOS000118884
ASA
Acenterine
Acesal
Acetal
Acetard
Aceticyl
Acetilsalicilico
Acetilum acidulatum
Acetisal
Acetol
Acetonyl
Acetophen
Acetosal
Acetosalic acid
Acetosalin
Acetoxybenzoic acid
Acetylin
Acetylsal
Acetylsalicylate
Acetylsalicylic acid
Acetylsalicylsaeure
Acetylsalicylsaure
Acetylsalycilic acid
Acetyonyl
Acetysal
Acetysalicylic acid
Acide 2-(acetyloxy)benzoique
Acide acetylsalicylique
Acide acétylsalicylique
Acido O-acetil-benzoico
Acido acetilsalicilico
Acidum acetylsalicylicum
Acimetten
Acisal
Acylpyrin
Adiro
Aloxiprimum
Asacard
Asagran
Asatard
Ascoden-30
Aspalon
Aspec
Aspergum
Aspir-Mox
Aspirdrops
Aspirin
Aspirin (JP15/USP)
Aspirin [BAN:JAN]
Aspirina 03
Aspirine
Asprin
Aspro
Aspro Clear
Asteric
Azetylsalizylsaeure
Azetylsalizylsäure
BIDD:GT0118
BRN 0779271
Bay-e-4465
Bayer
Bayer Aspirin 8 Hour
Bayer Buffered
Bayer Extra Strength Aspirin For Migraine Pain
Bayer Plus
Benaspir
Bi-prin
Bialpirina
Bialpirinia
Bufferin
C01405
CCRIS 3243
CHEBI:15365
CHEMBL25
CID2244
Caprin
Cardioaspirin
Cardioaspirina
Cemirit
Claradin
Clariprin
Colfarit
Contrheuma retard
Coricidin
Crystar
D00109
D001241
DB00945
Decaten
Delgesic
Dispril
DivK1c_000555
Dolean pH 8
Duramax
ECM
EINECS 200-064-1
EU-0100038
Easprin
Easprin (TN)
Ecolen
Ecotrin
Empirin
Empirin with Codeine
Endosprin
Endydol
 
Entericin
Enterophen
Enterosarein
Enterosarine
Entrophen
Extren
Globentyl
Globoid
HMS1920E13
HMS2090G03
HMS2091K13
HMS501L17
HSDB 652
Helicon
I14-7505
IDI1_000555
Idragin
Istopirin
KBio1_000555
KBio2_001725
KBio2_002271
KBio2_004293
KBio2_004839
KBio2_006861
KBio2_007407
KBio3_002149
KBio3_002751
KBioGR_000398
KBioGR_002271
KBioSS_001725
KBioSS_002272
Kapsazal
Kyselina 2-acetoxybenzoova
Kyselina acetylsalicylova
LS-143
Levius
Lopac-A-5376
Lopac0_000038
MLS001055329
MLS001066332
MLS001336045
MLS001336046
Magnecyl
Measurin
Medisyl
Micristin
MolPort-000-871-622
NCGC00015067-01
NCGC00015067-04
NCGC00015067-09
NCGC00090977-01
NCGC00090977-02
NCGC00090977-03
NCGC00090977-04
NCGC00090977-05
NCGC00090977-06
NCGC00090977-07
NCI60_002222
NINDS_000555
NSC 27223
NSC27223
NSC406186
Neuronika
Novid
Nu-seals
Nu-seals aspirin
O-(Acetyloxy)benzoate
O-(Acetyloxy)benzoic acid
O-Acetoxybenzoate
O-Acetoxybenzoic acid
O-Acetylsalicylic acid
O-Carboxyphenyl acetate
O-accetylsalicylic acid
O-acetylsalicylic acid
PL-2200
Persistin
Pharmacin
Pirseal
Polopirin
Polopiryna
Premaspin
R16CO5Y76E [UNII]
Rheumin tabletten
Rheumintabletten
Rhodine
Rhonal
Ronal
S-211
SMR000059138
SP 189
SPBio_001838
SPECTRUM1500130
ST075414
Salacetin
Salcetogen
Saletin
Salicylic acid acetate
Salicylic acid, acetate
Salospir
Solfrin
Solprin
Solprin acid
Solpyron
Solupsan
Spectrum2_001899
Spectrum3_001295
Spectrum4_000099
Spectrum5_000740
Spectrum_001245
Spira-Dine
St. Joseph
St. Joseph Aspirin for Adults
Supac
Tasprin
Temperal
Toldex
Triaminicin
Triple-sal
UNII R16CO5Y76E
UNII-R16CO5Y76E
UNII=R16CO5Y76E
UNM-0000306102
Vanquish
WLN: QVR BOV1
XAXA
Xaxa
Yasta
ZORprin
aspirin
cMAP_000006
component of Midol
component of Synirin
nchem.859-comp6
o-Acetoxybenzoic acid
o-Carboxyphenyl acetate
o-acetoxybenzoic acid
o-carboxyphenyl acetate
ácido acetilsalicílico
6
RivaroxabanapprovedPhase 3244366789-02-8
Synonyms:
BAY 59-7939
 
BAY59-7939
Xarelto
7
WarfarinapprovedPhase 345481-81-26691, 54678486
Synonyms:
(-)-Warfarin
(S)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone
(S)-Warfarin
(phenyl-1 acetyl-2 ethyl) 3-hydroxy-4 coumarin
(phenyl-1 acetyl-2 ethyl) 3-hydroxy-4 coumarine
1-(4'-Hydroxy-3'-coumarinyl)-1-phenyl-3-butanone
200 Coumarin
200 coumarin
3-(1'-Phenyl-2'-acetylethyl)-4-hydroxycoumarin
3-(Acetonylbenzyl)-4-hydroxycoumarin
3-(alpha-Acetonylbenzyl)-4-hydroxycoumarin
3-(alpha-Phenyl-beta-acetylaethyl)-4-hydroxycumarin
3-(alpha-Phenyl-beta-acetylethyl)-4-hydroxycoumarin
4-Hydroxy-3- (3-oxo-1-fenyl-butyl) cumarine
4-Hydroxy-3- (3-oxo-1-phenyl-butyl)-cumarin
4-Hydroxy-3-(3-oxo-1-fenyl-butyl) cumarine
4-Hydroxy-3-(3-oxo-1-phenyl-butyl)-cumarin
4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one
4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one
4-Hydroxy-3-(3-oxo-1-phenylbutyl)coumarin
4-Idrossi-3- (3-oxo-)-fenil-butil)-cumarine
4-Idrossi-3-(3-oxo-)-fenil-butil)-cumarine
4-Idrossi-3-(3-oxo-1-fenil-butil)-cumarine
45706_FLUKA
45706_RIEDEL
4oh-coumarin deriv.
5543-56-6
5543-57-7
81-81-2
A2250_FLUKA
A2250_SIGMA
AC-15978
AC1L1N37
AC1Q6AN3
AR-1E2310
Arab Rat Death
Arab rat death
Arab rat deth
Athrombin
Athrombin-K
Athrombin-k
Athrombine-K
Athrombine-k
BRD-A24514565-001-02-2
BRD-A24514565-236-01-6
BRN 1293536
BSPBio_002026
Bio-0586
Brumolin
C01541
C19H16O4
CBDivE_002127
CBDivE_013236
CBKinase1_000192
CBKinase1_012592
CHEBI:10033
CHEMBL1464
CID6691
CO-Rax
Caswell No. 903
Choice
Choice (TN)
Co-Rax
Co-rax
Compound 42
Coumadin
Coumadin Tabs
Coumafen
Coumafene
Coumafene [French]
Coumaphen
Coumaphene
Coumarins
Coumefene
Cov-R-Tox
Cov-R-tox
D-Con
D08682
DB00682
DL-3-(alpha-acetonylbenzyl)-4-hydroxycoumarin
Dethmor
Dethnel
Dicusat E
Dicusat e
DivK1c_000444
EINECS 201-377-6
EINECS 226-907-3
EPA Pesticide Chemical Code 086002
Eastern states duocide
Fasco fascrat powder
Frass-Ratron
Frass-ratron
HMS1921K07
HMS2092C20
HMS501G06
HSDB 1786
I14-0958
IDI1_000444
Jantoven
KBio1_000444
KBio2_000674
KBio2_003242
KBio2_005810
KBio3_001526
KBioGR_000901
KBioSS_000674
Killgerm sewarin p
Kumader
Kumadu
Kumatox
Kypfarin
LS-55083
Latka 42
Latka 42 [Czech]
Liqua-tox
MLS001304042
Maag Rattentod Cum
Maag rattentod cum
Mar-Frin
Mar-frin
Marevan
Martin'S mar-frin
Martin's mar-frin
 
Maveran
MolPort-001-787-822
Mouse pak
NCGC00094810-01
NCGC00094810-02
NCGC00159398-03
NCGC00178855-01
NINDS_000444
NSC 59813
NSC59813
PS104_SUPELCO
Panwarfin
Place-Pax
Place-pax
Prothromadin
RAX
RCR grey squirrel killer concentrate
RCRA waste no. P001
Rat & mice bait
Rat and mice bait
Rat-B-gon
Rat-Gard
Rat-Kill
Rat-Mix
Rat-O-cide #2
Rat-O-cide no. 2
Rat-Ola
Rat-Trol
Rat-a-way
Rat-alpha-way
Rat-b-gon
Rat-beta-gon
Rat-gard
Rat-kill
Rat-mix
Rat-o-cide #2
Rat-ola
Rat-trol
Ratorex
Ratox
Ratoxin
Ratron
Ratron G
Ratron g
Rats-no-more
Ratten-Koederrohr
Ratten-koederrohr
Rattenstreupulver Neu Schacht
Rattenstreupulver neu schacht
Rattenstreupulver new schacht
Rattentraenke
Rattunal
Rcra waste number P001
Ro-Deth
Ro-deth
Rodafarin
Rodafarin C
Rodafarin c
Rodex
Rodex blox
Rosex
Rough & ready mouse mix
Rough and ready mouse mix
SMP1_000316
SMR000718754
SPBio_000870
SPECTRUM1500613
STK364490
Sakarat
Sewarin
Sofarin
Solfarin
Sorexa Plus
Sorexa plus
Spectrum2_000935
Spectrum3_000583
Spectrum4_000381
Spectrum5_001751
Spectrum_000194
Spray-trol brand roden-trol
Temus W
Temus w
Tintorane
Tox-Hid
Tox-hid
Twin light rat away
UNII-5Q7ZVV76EI
Vampirinip II
Vampirinip III
Vampirinip iii
W.A.R.F. 42
WARF compound 42
WLN: T66 BOVJ DYR&1V1 EQ
Waran
Warf 10
Warf 42
Warfarat
Warfarin (INN)
Warfarin (and salts of)
Warfarin Plus
Warfarin Q
Warfarin [BSI:ISO]
Warfarin [INN:BAN]
Warfarin plus
Warfarin plus [discontinued]
Warfarin sodium
Warfarin titrated to an INR of 2.5-3.0
Warfarin(R)
Warfarina
Warfarina [INN-Spanish]
Warfarine
Warfarine [INN-French]
Warfarine [ISO-French]
Warfarinum
Warfarinum [INN-Latin]
Warficide
Warfilone
Zoocoumarin
Zoocoumarin [Netherlands and USSR]
Zoocoumarin [Russian]
delta-Con
nchembio.307-comp19
rac-Warfarin
warfarin
8
Tofacitinibapproved, investigationalPhase 3104477600-75-2
Synonyms:
 
Tasocitinib
Tofacitinibum
9
Folic Acidapproved, nutraceutical, vet_approvedPhase 3427959-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
Folsaeure
 
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
10
Phytonadioneapproved, NutraceuticalPhase 323084-80-04812, 5284607
Synonyms:
.alpha.-Phylloquinone
1,4-Naphthalenedione, 2-methyl-3-((2E,7R,11R)-3,7,11,15-tetramethyl-2-hexadecenyl)-, radical ion(1-)
10485-69-5
11104-38-4
15973-57-6
2', 3'-trans-Vitamin K1
2',3'-trans-Vitamin K1
2-(3,7,11,15-Tetramethylhexadec-2-enyl)-3-methylnaphthalene-1,4-dione
2-METHYL-3-PHYTYL-14-NAPHTHOQUINONE
2-Methyl-3-(3,7,11,15-tetramethyl-2-hexadecenyl)-1,4-naphthalened- ione
2-Methyl-3-(3,7,11,15-tetramethyl-2-hexadecenyl)-1,4-naphthalenedione
2-Methyl-3-(3,7,11,15-tetramethylhexadec-2-enyl)-1,4-naphthoquinone
2-Methyl-3-[(2e)-3,7,11,15-tetramethyl-2-hexadecenyl]naphthoquinone
2-Methyl-3-phythyl-1,4-naphthochinon
2-Methyl-3-phytyl-1,4-naphthochinon
2-Methyl-3-phytyl-1,4-naphthochinon [German]
2-Methyl-3-phytyl-1,4-naphthoquinone
2-methyl-3-(3,7,11,15-tetramethylhexadec-2-en-1-yl)naphthalene-1,4-dione
2-methyl-3-[(E)-3,7,11,15-tetramethylhexadec-2-enyl]naphthalene-1,4-dione
27696-10-2
3-Phytylmenadione
50926-17-5
84-80-0
AC1NQX34
AC1Q6B3J
AR-1E3503
Antihemorrhagic vitamin
Aqua mephyton
Aqua-Mephytin
Aquamephyton
C02059
C31H46O2
CID5280483
Combinal K1
D00148
DB01022
EINECS 201-564-2
EINECS 234-330-3
EINECS 279-833-9
Fitomenadiona
Fitomenadiona [INN-Spanish]
Fitomenadione
Fitomenadione [DCIT]
HSDB 3162
K-Ject
Kativ N
Kephton
 
Kinadion
Konakion
LS-94617
LT00452032
MLS001332659
MLS001332660
Mephyton
Mephyton (TN)
MolPort-001-785-978
Mono-Kay
Monodion
NCGC00159423-02
NSC 270681
NSC270681
P0642
Phyllochinon
Phyllochinon [German]
Phyllochinonum
Phylloquinone
Phylloquinone (8CI)
Phythyl-menadion
Phythyl-menadion (GERMAN)
Phytomenadione
Phytomenadione (INN)
Phytomenadionum
Phytomenadionum [INN-Latin]
Phytonadione
Phytonadione (JP15/USP)
Phytonadione [USAN:JAN]
Phytonadionum
Phytylmenadione
SMR000059144
ST075162
Synthex P
UNII-A034SE7857
VITAMIN K
VITAMIN K1
Vitamin K
Vitamin K 1
Vitamin K1
Vitamin K1 (TN)
Vitamin K1 (VAN)
Vitamin K1 (generic)
Vitamin K1(20)
alpha-Phylloquinone
phyllohydroquinone
phytonadione
trans-Phylloquinone
α-phylloquinone
11
Menadioneapproved, nutraceuticalPhase 323058-27-54055
Synonyms:
03AAE1E9-B215-45AF-976C-91E61894A467
1,4-Naphthalenedione, 2-methyl-, radical ion(1-)
2-Methyl-1,4-Naphthalenedione
2-Methyl-1,4-naftochinon
2-Methyl-1,4-naftochinon [Czech]
2-Methyl-1,4-naphthalendione
2-Methyl-1,4-naphthalenedione
2-Methyl-1,4-naphthochinon
2-Methyl-1,4-naphthochinon [German]
2-Methyl-1,4-naphthodione
2-Methyl-1,4-naphthoquinone
2-Methylnaphthoquinone
2-methyl-1,4-naphthoquinone, 5
2-methylnaphthalene-1,4-dione
3-Methyl-1,4-naphthoquinone
34524-96-4
47775_SUPELCO
58-27-5
72060-21-0
AC1L1HBA
AC1Q2HB3
AI3-14700
AKOS004910447
ARONIS24154
Aquakay
Aquinone
BB_NC-2319
BIDD:ER0556
BPBio1_000592
BSPBio_000538
Bio1_000471
Bio1_000960
Bio1_001449
C05377
C11H8O2
CAS-58-27-5
CCRIS 6672
CHEBI:28869
CHEMBL590
CID4055
CPD-3766
D02335
DB00170
DivK1c_000080
DivK1c_006287
EINECS 200-372-6
HMS1569K20
HMS1921P06
HMS2092F12
HMS500D22
HSDB 3354
Hemodal
I14-2821
IDI1_000080
InChI=1/C11H8O2/c1-7-6-10(12)8-4-2-3-5-9(8)11(7)13/h2-6H,1H
Juva-K
K-Thrombyl
K-Vitan
KBio1_000080
KBio1_001231
KBio2_001708
KBio2_002527
KBio2_004276
KBio2_005095
KBio2_006844
KBio2_007663
KBio3_003005
KBioGR_000984
KBioGR_002527
KBioSS_001708
KBioSS_002535
Kaergona
Kanone
Kappaxan
Kappaxan (VAN)
Kappaxin
Kappaxin (TN)
Karcon
Kareon
Kativ-G
Kayklot
Kaykot
 
Kaynone
Kayquinone
Kipca
Kipca, oil soluble
Kipca-Oil Soluble
Klottone
Koaxin
Kolklot
LS-95653
LS-95654
M0373
M5625_SIGMA
M9429_SIGMA
MLS000069420
MLS001148443
MNQ
Memodol
Menadion
Menadione
Menadione (K3)
Menadione (USP)
Menadione [USAN:BAN]
Menadione semiquinone
Menadionum
Menaphthene
Menaphthon
Menaphthone
Menaphtone
Menaquinone
Menaquinone 0
Menaquinone O
Methyl-1,4-naphthalenedione
Methyl-1,4-naphthoquinone
Methylnaphthoquinone
Mitenon
Mitenone
MolPort-001-766-699
NCGC00016258-01
NCGC00094978-01
NCGC00094978-02
NCI60_003945
NCIMech_000105
NINDS_000080
NSC 4170
NSC4170
Panosine
Prestwick0_000459
Prestwick1_000459
Prestwick2_000459
Prestwick3_000459
Prestwick_313
Prokayvit
QTL1_000056
S1949_Selleck
SMR000059102
SMR000653532
SPBio_001267
SPBio_002477
SPECTRUM1502254
SpecPlus_000191
Spectrum2_001194
Spectrum4_000722
Spectrum5_001764
Spectrum_001228
Synkay
Thyloquinone
UNII-723JX6CXY5
Usaf ek-5185
VK3
Vicasol
Vitamin K 3
Vitamin K0
Vitamin K2
Vitamin K2(0)
Vitamin K3
Vitamin K3 : 2-Methyl-1,4-naphthoquinone
Vitamin K3: 1,4-Dihydro-1,4-dioxo-2-methylnaphthalene
Vitamin-?K3
WLN: L66 BV EVJ C1
ZINC00001677
cMAP_000077
menadione
nchembio.109-comp5
12AntibodiesPhase 3, Phase 2, Phase 16045
13Gastrointestinal AgentsPhase 38109
14Antibodies, MonoclonalPhase 3, Phase 2, Phase 13795
15ImmunoglobulinsPhase 3, Phase 2, Phase 16045
16Vitamin B ComplexPhase 34229
17AntimetabolitesPhase 311774
18Dermatologic AgentsPhase 35674
19Immunosuppressive AgentsPhase 312770
20Antimetabolites, AntineoplasticPhase 37171
21Antirheumatic AgentsPhase 3, Phase 2, Early Phase 110627
22Folic Acid AntagonistsPhase 32200
23Nucleic Acid Synthesis InhibitorsPhase 34855
24Pharmaceutical SolutionsPhase 3, Phase 2, Phase 17793
25Interleukin 1 Receptor Antagonist ProteinPhase 2, Phase 396
26Analgesics, Non-NarcoticPhase 36260
27AnalgesicsPhase 311287
28Anti-Inflammatory Agents, Non-SteroidalPhase 34295
29Anti-Inflammatory AgentsPhase 310355
30Natriuretic Peptide, BrainPhase 2, Phase 3178
31Peripheral Nervous System AgentsPhase 3, Phase 122776
32Protein Kinase InhibitorsPhase 33612
33MicronutrientsPhase 35802
34Platelet Aggregation InhibitorsPhase 32419
35
protease inhibitorsPhase 35320
Synonyms:
 
protease inhibitors
36Trace ElementsPhase 35802
37VitaminsPhase 35095
38Serine Proteinase InhibitorsPhase 3850
39CoagulantsPhase 31428
40AntithrombinsPhase 3672
41Antithrombin IIIPhase 3665
42AntipyreticsPhase 31534
43Antifibrinolytic AgentsPhase 3459
44AnticoagulantsPhase 32516
45Cyclooxygenase InhibitorsPhase 32778
46HIV Protease InhibitorsPhase 35319
47HemostaticsPhase 31359
48Fibrinolytic AgentsPhase 32317
49Factor Xa InhibitorsPhase 3391
50Folinic AcidNutraceuticalPhase 33150

Interventional clinical trials:

(show top 50)    (show all 66)
idNameStatusNCT IDPhase
1A Study of Decreased Dose Frequency in Participants With Systemic Juvenile Arthritis Who Experience Laboratory Abnormalities During Treatment With RoActemra/Actemra (Tocilizumab)RecruitingNCT01734382Phase 4
2Erosive Osteoarthritis of the Hands: Treatment by Methotrexate Versus PlaceboUnknown statusNCT01068405Phase 3
3Infliximab Therapy in Patients With Refractory Polymyalgia RheumaticaUnknown statusNCT01423591Phase 3
4Does Etanercept Influence Tweak Modulation of Inflammation During Inflammatory Rheumatisms (Psoriatic Arthritis and Rheumatoid Arthritis)?CompletedNCT02164214Phase 3
5Mobile Health in Structural Heart DiseaseCompletedNCT02881398Phase 2, Phase 3
6An Open-label Extension Study of Canakinumab in Patients With Systemic Juvenile Idiopathic Arthritis and Active Systemic Manifestations Manifestations and Response Characterization Study in Canakinumab Treatment-naïve Patients With Active SJIA With and WiCompletedNCT00891046Phase 3
7A Study of RoActemra/Actemra (Tocilizumab) in Patients With Active Systemic Juvenile Idiopathic Arthritis (JIA)CompletedNCT00642460Phase 3
8Study of the Safety and Efficacy of NC-503 in Secondary (AA) AmyloidosisCompletedNCT00035334Phase 2, Phase 3
9Interleukin-1 Receptor Antagonist (IL-1RA) (ANAKINRA) IN SEVERE SYSTEMIC-ONSET JUVENILE IDIOPATHIC ARTHRITISCompletedNCT00339157Phase 2, Phase 3
10INVestIgation of rheumatiC AF Treatment Using Vitamin K Antagonists, Rivaroxaban or Aspirin Studies, SuperiorityNot yet recruitingNCT02832531Phase 3
11INVestIgation of rheumatiC AF Treatment Using Vitamin K Antagonists, Rivaroxaban or Aspirin Studies, Non-InferiorityNot yet recruitingNCT02832544Phase 3
12A Safety, Efficacy And Pharmacokinetics Study Of Tofacitinib In Pediatric Patients With sJIANot yet recruitingNCT03000439Phase 3
13Safety and Efficacy Study of Etanercept (Enbrel®) In Children With Systemic Onset Juvenile Rheumatoid ArthritisTerminatedNCT00078806Phase 3
14Efficacy of Physiotherapy on the Health and Quality of Life of the Rheumatic PatientUnknown statusNCT02020668Phase 2
15Efficacy and Safety of Tocilizumab in Adult's Still DiseaseUnknown statusNCT01002781Phase 2
16Preventive Measures for Childhood-Onset Obsessive-Compulsive Disorder and Tic Disorders (PANDAS Subgroup)CompletedNCT00001359Phase 2
17N-acetylcysteine for Renal Protection in Patients With Rheumatic Heart Disease Undergoing Valve ReplacementCompletedNCT01704482Phase 2
18Validity Study of Glutamine to Improve Cardiac Function in Cardiac SurgeryCompletedNCT01794884Phase 2
19Mild Water-Filtered Near Infrared Whole-Body-Hyperthermia as an Adjunct in the Treatment of FibromyalgiaCompletedNCT00324441Phase 2
20Safety and Effectiveness of Rilonacept for Treating Systemic Juvenile Idiopathic Arthritis in Children and Young AdultsCompletedNCT00534495Phase 2
21Interleukin-1 Trap to Treat Autoinflammatory DiseasesCompletedNCT00094900Phase 2
22Therapeutic Use of Tadekinig Alfa in Adult-onset Still's DiseaseCompletedNCT02398435Phase 2
23Safety, Efficacy and Pharmacokinetics of Subcutaneous ACZ885 in Patients With Systemic Juvenile Idiopathic Arthritis (SJIA)CompletedNCT00426218Phase 1, Phase 2
24TIV and High Dose TIV in Subjects With Rheumatoid ArthritisCompletedNCT01436370Phase 2
25Clinical Trial of Gut Microbiota in the Management of Immune ThrombocytopeniaRecruitingNCT03033199Phase 2
26A Repeated Dose-finding Study of Sarilumab in Children and Adolescents With Systemic Juvenile Idiopathic Arthritis (sJIA)RecruitingNCT02991469Phase 2
27Phase I Clinical Trial to Evaluate the Safety, Tolerability and Pharmacokinetics of YHB1411-2 in Healthy Male VolunteersCompletedNCT01525147Phase 1
28Dental Anesthesia in Pregnant Women With Rheumatic Heart DiseaseCompletedNCT00482573Phase 1
29Development of Intervention Model for Osteoporosis and Fall Prevention in TaiwanUnknown statusNCT01206491
30The Prevalence of Rheumatic Heart Disease in School Children in FijiUnknown statusNCT00779662
31Rheumatic Heart Disease Prevalence in Leon, NicaraguaUnknown statusNCT00307112
3241.8 Degree Centigrade Whole Body Hyperthermia for the Treatment of Rheumatoid DiseasesUnknown statusNCT00000106
33Plasma Adiponectin Levels and Relations With Cytokines in Children With Acute Rheumatic FeverCompletedNCT01886846
34Hospital Based Incidence of Group A Streptococcal Disease in FijiCompletedNCT00264771
35Evaluation of a Regional Healthy Skin Program in Remote Aboriginal Communities of Australia's Northern TerritoryCompletedNCT00884728
36Rheumatic Heart Disease in Peru: Prevalence and Cardiovascular Outcomes Among SchoolchildrenCompletedNCT02353663
37Impact of a Telenursing Service on Satisfaction and Health Outcomes of Children With Inflammatory Rheumatic DiseasesCompletedNCT01511341
38Surveillance of Streptococcal Infections in Children in IndiaCompletedNCT00342199
39Etude 3000 ARTHROSES Symptomatic Knee and Hip Osteoarthritis Prevalence SurveyCompletedNCT01400529
40Study of the Influence of the Expression of the Calcium-sensitive Receptor (CaSR) by Monocytes in the Synovial Liquid on Structural Alterations in Patients Diagnosed With Rheumatoid Arthritis in the Previous Two YearsCompletedNCT02894047
41C.O.R.P.U.S.: Observational Cohort of Adult and Child Inflammatory Arthritis in FranceCompletedNCT02886689
42Genetic Susceptibility to Rheumatic Heart Disease in the Pacific RegionCompletedNCT02188862
43Effect of Rheumatic Heart Disease on Maternal and Fetal OutcomesCompletedNCT03029117
44Rheumatic Heart Disease Study in LusakaCompletedNCT02661763
45DNA Typing of HLA-DR/DQ Alleles in Taiwan Chinese With Rheumatic Heart DiseaseCompletedNCT00264524
46Effect of Simvastatin on Cardiac FunctionCompletedNCT01178710
47Deep Versus Superficial Heating in Patients With Knee OsteoarthritisCompletedNCT01343147
48Risk of Coccidioidomycosis in Patients Receiving Anti-TNF and Other Biologic Agents for an Inflammatory ArthritisCompletedNCT00796809
49Study Medication Adherence and Its Determinants in Chronic Disease Through the Example of Methotrexate in Chronic Inflammatory RheumatismRecruitingNCT02926560
50Regulatory B Cells in Inflammatory Rheumatisms and Biomarkers of Response to Biologic TreatmentsRecruitingNCT01642706

Search NIH Clinical Center for Rheumatic Fever

Inferred drug relations via UMLS68/NDF-RT46:


Cochrane evidence based reviews: rheumatic fever

Genetic Tests for Rheumatic Fever

About this section

Anatomical Context for Rheumatic Fever

About this section

MalaCards organs/tissues related to Rheumatic Fever:

36
Heart, Skin, Brain, B cells, Bone, Monocytes, Liver

Publications for Rheumatic Fever

About this section

Articles related to Rheumatic Fever:

(show top 50)    (show all 648)
idTitleAuthorsYear
1
Acute rheumatic fever outbreak in southern central European country. (27815733)
2017
2
Acute rheumatic fever and exposure to poor housing conditions in New Zealand: A descriptive study. (28052445)
2017
3
Significance of silent carditis and investigation of follow-up signs in acute rheumatic fever. (27097234)
2016
4
Serological Evidence of Immune Priming by Group A Streptococci in Patients with Acute Rheumatic Fever. (27499748)
2016
5
A Cost-Effectiveness Tool to Guide the Prioritization of Interventions for Rheumatic Fever and Rheumatic Heart Disease Control in African Nations. (27512994)
2016
6
Interleukin-10: Role in increasing susceptibility and pathogenesis of rheumatic fever/rheumatic heart disease. (27918954)
2016
7
2016 National Rheumatic Fever Week: The status of rheumatic heart disease in South Africa. (27499394)
2016
8
Tracking isolated myocarditis in a young adult with acute rheumatic fever on cardiac magnetic resonance imaging. (27526359)
2016
9
Junctional tachycardia in a child with non-rheumatic fever streptococcal pharyngitis. (27989256)
2016
10
Update on diagnosis of acute rheumatic fever: 2015 Jones criteria. (27103858)
2016
11
Rheumatic Fever and Rheumatic Heart Disease a Historical Perspective. (27867464)
2016
12
Advanced heart block in acute rheumatic fever. (27053901)
2016
13
Sugar, dental caries and the incidence of acute rheumatic fever: a cohort study of MA8ori and Pacific children. (27836917)
2016
14
CHANGING CLINICAL PROFILE OF ACUTE RHEUMATIC FEVER AND RHEUMATIC RECURRENCE. (27323580)
2016
15
WHAT IS ACUTE RHEUMATIC FEVER (ARF) AND RHEUMATIC HEART DISEASE (RHD)? (27132395)
2016
16
Post-Streptococcal Autoimmune Sequelae: Rheumatic Fever and Beyond (26866235)
2016
17
Acute poststreptococcal glomerulonephritis and acute rheumatic fever: An uncommon coincidence. (27625530)
2016
18
Acute Rheumatic Fever: Global Persistence of a Preventable Disease. (27776916)
2016
19
Estimating the risk of acute rheumatic fever in New Zealand by age, ethnicity and deprivation. (27311633)
2016
20
Nurse-led school-based clinics for rheumatic fever prevention and skin infection management: evaluation of Mana Kidz programme in Counties Manukau. (27348871)
2016
21
Rheumatic fever and rheumatic heart disease in Bangladesh: A review. (26896274)
2016
22
Acute Rheumatic Fever: An Evidence-Based Approach To Diagnosis And Initial Management. (27462838)
2016
23
Acute Rheumatic Fever with Erythema Marginatum. (28002702)
2016
24
Mitral valve enhancement in a patient with active Rheumatic Fever: An uncommon phenomenon on the MRI examination with possible clinical significance. (27878698)
2016
25
Rheumatic Fever: a neglected and underdiagnosed disease. New perspective on diagnosis and prevention. (27982273)
2016
26
Cardiac Myosin Epitopes Recognized by Autoantibody in Acute and Convalescent Rheumatic Fever. (27273689)
2016
27
Sharing success - understanding barriers and enablers to secondary prophylaxis delivery for rheumatic fever and rheumatic heart disease. (27581750)
2016
28
An epidemiological study to assess the true incidence and prevalence of rheumatic heart disease and acute rheumatic fever in New Caledonian schoolchildren. (27203400)
2016
29
Long-Term Outcomes From Acute Rheumatic Fever and Rheumatic Heart Disease: A Data-Linkage and Survival Analysis Approach. (27407071)
2016
30
Association between rheumatic fever and Takayasu's arteritis - Case report. (27267532)
2016
31
Preliminary consultation on preferred product characteristics of benzathine penicillin G for secondary prophylaxis of rheumatic fever. (27465618)
2016
32
Acute rheumatic fever and rheumatic heart disease. (27188830)
2016
33
Acute rheumatic fever and rheumatic heart disease. (27228242)
2016
34
Administering intramuscular penicillin injections to reduce rheumatic fever. (27281906)
2016
35
Arterial stiffness during acute and recovery phases of children with rheumatic fever. (27130739)
2016
36
A Review of Acute Rheumatic Fever and Rheumatic Heart Disease Research in Malaysia. (27801390)
2016
37
Primary Prevention of Rheumatic Fever. (27351359)
2016
38
Atypical arthritis revisited: Acute rheumatic fever. (27212853)
2016
39
Peculiarities of the Clinical Course of Oxidative Protein and Lipid Modification in Children with Acute Rheumatic Fever. (27774884)
2016
40
Difficulties in the differential diagnosis between Takayasu arteritis and rheumatic fever: case report. (27267341)
2016
41
Controlling acute rheumatic fever and rheumatic heart disease in developing countries: are we getting closer? (25490689)
2015
42
Geoepidemiological hints about Streptococcus pyogenes strains in relationship with acute rheumatic fever. (25772310)
2015
43
Late Recurrence of Rheumatic Fever. (26270640)
2015
44
Childhood nutrition and prevention of rheumatic fever. (25754573)
2015
45
A Case of Adult-Onset Acute Rheumatic Fever With Long-Lasting Atrioventricular Block Requiring Permanent Pacemaker Implantation. (26549396)
2015
46
Rheumatic fever: a forgotten but still existing cause of fever of unknown origin detected on FDG PET/CT. (25546214)
2015
47
Historical aspects of rheumatic fever. (25586841)
2015
48
A cost-effectiveness analysis of a program to control rheumatic Fever and rheumatic heart disease in pinar del rio, cuba. (25768008)
2015
49
IgA-dominant acute poststreptococcal glomerulonephritis with concomitant rheumatic fever successfully treated with steroids: a case report. (26718763)
2015
50
Are minor echocardiographic changes associated with an increased risk of acute rheumatic fever or progression to rheumatic heart disease? (26163902)
2015

Variations for Rheumatic Fever

About this section

Expression for genes affiliated with Rheumatic Fever

About this section
Search GEO for disease gene expression data for Rheumatic Fever.

Pathways for genes affiliated with Rheumatic Fever

About this section

Pathways related to Rheumatic Fever according to GeneCards Suite gene sharing:

(show all 21)
idSuper pathwaysScoreTop Affiliating Genes
19.5CD40LG, TLR2, TNF
29.5CD40LG, TLR2, TNF
39.4HLA-DRB1, MBL2, TLR2
49.3HLA-DRB1, MASP2, MBL2
59.3IL2, TNF
69.3HLA-DRB1, TLR2, TNF
79.3HLA-DRB1, TLR2, TNF
89.1HLA-DRB1, IL2
9
Show member pathways
9.0IL2, TLR2, TNF
10
Show member pathways
8.9CD40LG, IL2, TNF
118.9CD40LG, IL2, TNF
12
Show member pathways
8.9CD40LG, HLA-DRB1, TLR2, TNF
13
Show member pathways
8.9FCN2, FCN3, MASP2, MBL2
148.8HLA-DRB1, IL2, TNF
15
Show member pathways
8.6CD40LG, IL2, TLR2, TNF
168.6CD40LG, IL2, TLR2, TNF
17
Show member pathways
8.5FCN1, FCN2, FCN3, MASP2, MBL2
18
Show member pathways
8.5HLA-DRB1, IL2, TLR2, TNF
19
Show member pathways
8.4CD40LG, HLA-DRB1, IL2, TNF
20
Show member pathways
8.1CD40LG, HLA-DRB1, IL2, TLR2, TNF
21
Show member pathways
6.1CD40LG, FCN1, FCN2, FCN3, HLA-DRB1, IL2

GO Terms for genes affiliated with Rheumatic Fever

About this section

Cellular components related to Rheumatic Fever according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1blood microparticleGO:00725629.6FCN2, FCN3, HP
2collagen trimerGO:00055819.5FCN1, FCN2, FCN3, MBL2
3cell surfaceGO:00099869.4CD40LG, HLA-DRB1, MBL2, TLR2, TNF
4extracellular regionGO:00055766.7FCN1, FCN2, FCN3, HP, IL2, MASP2

Biological processes related to Rheumatic Fever according to GeneCards Suite gene sharing:

(show all 16)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of interleukin-10 productionGO:003273310.5CD40LG, TLR2
2positive regulation of interleukin-12 productionGO:003273510.5CD40LG, TLR2
3negative regulation of growth of symbiont in hostGO:004413010.5MBL2, TNF
4positive regulation of chemokine productionGO:003272210.5TLR2, TNF
5positive regulation of interleukin-8 productionGO:003275710.5TLR2, TNF
6positive regulation of NF-kappaB import into nucleusGO:004234610.5TLR2, TNF
7opsonizationGO:000822810.4FCN2, MBL2
8negative regulation of viral entry into host cellGO:004659710.3FCN1, FCN3
9positive regulation of NF-kappaB transcription factor activityGO:005109210.1CD40LG, TLR2, TNF
10defense response to bacteriumGO:00427429.9HP, MBL2, TNF
11regulation of immunoglobulin secretionGO:00510239.8CD40LG, TNF
12defense response to Gram-positive bacteriumGO:00508309.7FCN2, MBL2, TLR2, TNF
13recognition of apoptotic cellGO:00436549.2FCN1, FCN2, FCN3
14complement activationGO:00069569.2FCN1, FCN2, FCN3, MASP2, MBL2
15complement activation, lectin pathwayGO:00018679.2FCN1, FCN2, FCN3, MASP2, MBL2
16proteolysisGO:00065088.8FCN1, FCN2, FCN3, MASP2, MBL2

Molecular functions related to Rheumatic Fever according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1calcium-dependent protein bindingGO:004830610.0FCN2, MASP2, MBL2
2signaling pattern recognition receptor activityGO:00083299.8FCN1, TLR2
3cytokine activityGO:00051259.5CD40LG, IL2, TNF
4serine-type endopeptidase activityGO:00042528.7FCN1, FCN2, FCN3, MASP2, MBL2

Sources for Rheumatic Fever

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet