MCID: RHN004
MIFTS: 60

Rhinitis malady

Categories: Respiratory diseases, Smell/Taste diseases

Aliases & Classifications for Rhinitis

Aliases & Descriptions for Rhinitis:

Name: Rhinitis 12 29 52 42 14 69
Runny Nose 12 3

Classifications:



External Ids:

Disease Ontology 12 DOID:4483
MeSH 42 D012220
NCIt 47 C34986
SNOMED-CT 64 70076002
UMLS 69 C0035455

Summaries for Rhinitis

Disease Ontology : 12 A upper respiratory infectious disease which involves irritation and inflammation of the mucous membrane of the nose due to viruses, bacteria or irritants. The inflammation results in generation of excessive amounts of mucus leading to runny nose, as well as nasal congestion and post-nasal drip.

MalaCards based summary : Rhinitis, also known as runny nose, is related to neonatal jaundice and pulmonary tuberculosis, and has symptoms including nasal congestion (finding), posterior rhinorrhea and sinus congestion. An important gene associated with Rhinitis is RNASE3 (Ribonuclease A Family Member 3), and among its related pathways/superpathways are Innate Immune System and PEDF Induced Signaling. The drugs Allegra and Allegra-D have been mentioned in the context of this disorder. Affiliated tissues include testes, skin and t cells, and related phenotypes are growth/size/body region and hematopoietic system

CDC : 3 Common colds are the main reason that children miss school and adults miss work. Each year in the United States, there are millions of cases of the common cold. Adults have an average of 2-3 colds per year, and children have even more.

Wikipedia : 71 Rhinitis, also known as coryza, is irritation and inflammation of the mucous membrane inside the nose.... more...

Related Diseases for Rhinitis

Diseases in the Rhinitis family:

Chronic Rhinitis

Diseases related to Rhinitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 228)
id Related Disease Score Top Affiliating Genes
1 neonatal jaundice 29.3 CCL5 ICAM1 IL4
2 pulmonary tuberculosis 29.0 CCL11 CCL5 CXCL8 IGHE IL13 IL4
3 allergic rhinitis 12.6
4 chronic rhinitis 12.4
5 vasomotor rhinitis 12.3
6 atrophic rhinitis 12.3
7 pollen allergy 11.2
8 olfactory neuroblastoma 11.2
9 common cold 11.1
10 atopy 11.1
11 allergic conjunctivitis 11.1
12 measles 11.1
13 actinobacillosis 11.0
14 wegener granulomatosis 11.0
15 asthma-related traits 4 10.7
16 loeys-dietz syndrome 1 10.7
17 asthma, aspirin-induced 10.7
18 congenital syphilis 10.7
19 asthma 10.7
20 nasopharyngitis 10.5
21 renal hypertension 10.3 IL13 IL5 RNASE3
22 dahlberg borer newcomer syndrome 10.3 IL13 IL5
23 lens-induced iridocyclitis 10.3 IL4 IL5 RNASE3
24 papillary squamous carcinoma 10.3 IGHE IL4 IL5
25 anterior dislocation of lens 10.3 CCL11 IL4 RNASE3
26 crustacean allergy 10.3 IL13 IL4 IL4R
27 spastic diplegia 10.3 CCL11 IL13 IL5
28 goat milk allergy 10.3 IL13 IL4 IL4R
29 disordered steroidogenesis due to cytochrome p450 oxidoreductase 10.3 CCL11 IL13 IL5
30 pharyngitis 10.3
31 bone peripheral neuroepithelioma 10.3 IL13 IL4 IL5
32 appendix carcinoid tumor 10.3 EPX NGF RNASE3
33 indian plum allergy 10.3 IL13 IL4 IL5
34 isolated klippel-feil syndrome 10.3 IGHE IL4 IL5
35 lactose intolerance 10.3 IL13 IL4 IL5
36 askin's tumor 10.3 IL13 IL4 IL5
37 orbit alveolar rhabdomyosarcoma 10.3 IL4 IL5 RNASE3
38 duodenal somatostatinoma 10.3 IL13 IL4 IL5
39 psychotic disorder 10.3 CCL11 CXCL8 IL4
40 multiple epiphyseal dysplasia due to collagen 9 anomaly 10.3 IGHE IL4 IL5 RNASE3
41 retinal vascular disease 10.3 CCL11 CXCL8 IL4
42 dissociated nystagmus 10.3 EPX IL4 IL5
43 loiasis 10.3 IL13 IL4 IL5
44 wilkes stevenson syndrome 10.3 CXCL8 IL5 RNASE3
45 breast intracanalicular fibroadenoma 10.3 CXCL8 IL4 IL5
46 lymphangiectasia, intestinal 10.3 IL4 NGF RNASE3
47 marasmus 10.3 IL4 IL5 NGF RNASE3
48 actinic keratosis 10.3 IL13 IL4 IL5 RNASE3
49 necrotizing gastritis 10.3 CCL11 EPX IL5 RNASE3
50 thelaziasis 10.3 CCL11 IL13 IL4 IL5

Graphical network of the top 20 diseases related to Rhinitis:



Diseases related to Rhinitis

Symptoms & Phenotypes for Rhinitis

UMLS symptoms related to Rhinitis:


nasal congestion (finding), posterior rhinorrhea, sinus congestion, nasal irritation, rhinorrhea

MGI Mouse Phenotypes related to Rhinitis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 growth/size/body region MP:0005378 10.03 FOXJ1 HRH1 ICAM1 IL13 IL4 IL4R
2 hematopoietic system MP:0005397 9.93 NR3C1 POMC VCAM1 CCL11 CCL5 EPX
3 digestive/alimentary MP:0005381 9.87 IL5 NR3C1 FOXJ1 ICAM1 IL13 IL4
4 immune system MP:0005387 9.77 CCL11 CCL5 CYSLTR1 EPX HRH1 ICAM1
5 respiratory system MP:0005388 9.23 CCL11 CYSLTR1 FOXJ1 IL13 IL4 IL4R

Drugs & Therapeutics for Rhinitis

FDA approved drugs:

(show all 18)
id Drug Name Active Ingredient(s) 17 Company Approval Date
1
Allegra 17 FEXOFENADINE HYDROCHLORIDE Hoechst Marion Roussel Approved July 1996
2
Allegra-D 17 FEXOFENADINE HYDROCHLORIDE; PSEUDOEPHEDRINE HYDROCHLORIDE Hoechst Marion Roussel Approved March 1998
3
Astelin nasal spray 17 AZELASTINE HYDROCHLORIDE Wallace Laboratories Approved November 1996
4
Atrovent 17 IPRATROPIUM BROMIDE Boehringer Ingelheim Approved January 1996
5
Clarinex 17 DESLORATADINE Schering-Plough Approved February 2002
6
Clemastine fumarate syrup 17 CLEMASTINE FUMARATE Morton Grove Pharmaceuticals Approved March 1998
7
Dymista 17 AZELASTINE HYDROCHLORIDE; FLUTICASONE PROPIONATE Meda Pharmaceuticals Inc Approved May 2012
8
Flonase Nasal Spray 17 FLUTICASONE PROPIONATE GlaxoSmithKline Approved November 1997
9
Grastek 17 Timothy Grass Pollen Allergen Extract Merck Approved April 2014
10
Nasacort AQ Nasal Spray 17 TRIAMCINOLONE ACETONIDE Phone-Poulenc Rorer Approved October 1997
11
Oralair 17 Greer Labs Approved April 2014
12
Patanase 17 OLOPATADINE HYDROCHLORIDE Alcon Approved April 2008
13
Qnasl 17 BECLOMETHASONE DIPROPIONATE Teva Pharmaceutical Approved March 2012
14
Ragwitek 17 Merck Approved April 2014
15
Rhinocort Aqua Nasal Spray 17 BUDESONIDE AstraZeneca Approved October 1999
16
Tri-Nasal Spray 17 Muro Pharmaceutical Approved February 2000
17
Xyzal 17 LEVOCETIRIZINE DIHYDROCHLORIDE UCB Approved May 2007
18
Zyrtec 17 CETIRIZINE HYDROCHLORIDE Pfizer Approved December 1995

Drugs for Rhinitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 365)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Histamine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 75614-87-8, 51-45-6 774
2
Capsaicin Approved Phase 4,Phase 2,Phase 1 404-86-4 1548943
3
Cetirizine Approved Phase 4,Phase 3,Phase 2,Phase 1 83881-51-0 2678
4
Montelukast Approved Phase 4,Phase 3,Phase 2,Phase 1 158966-92-8 5281040
5
Nitric Oxide Approved Phase 4,Phase 1,Phase 2 10102-43-9 145068
6
Lansoprazole Approved, Investigational Phase 4 103577-45-3 3883
7
Levocetirizine Approved Phase 4,Phase 3,Phase 2,Phase 1 130018-77-8
8
Budesonide Approved Phase 4,Phase 3,Phase 2 51333-22-3 63006 5281004
9
Desloratadine Approved, Investigational Phase 4,Phase 3,Phase 2 100643-71-8 124087
10
Loratadine Approved Phase 4,Phase 3,Phase 2 79794-75-5 3957
11
Ephedrine Approved Phase 4,Phase 3,Phase 2,Phase 1 299-42-3 9294
12
Oxymetazoline Approved Phase 4,Phase 3,Phase 2,Phase 1 1491-59-4 4636
13
Phenylephrine Approved Phase 4,Phase 3,Phase 2,Phase 1 59-42-7 6041
14
Pseudoephedrine Approved Phase 4,Phase 3,Phase 2,Phase 1 90-82-4 7028
15
Betamethasone Approved, Vet_approved Phase 4,Phase 3 378-44-9 9782
16
Azelastine Approved Phase 4,Phase 3,Phase 2,Phase 1 58581-89-8 2267
17
Xylometazoline Approved Phase 4 526-36-3 5709
18
Omalizumab Approved, Investigational Phase 4,Phase 2,Phase 1 242138-07-4
19
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3 83-43-2 6741
20
Prednisolone Approved, Vet_approved Phase 4,Phase 3 50-24-8 5755
21
Ciclesonide Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 126544-47-6, 141845-82-1 444033
22
Fexofenadine Approved Phase 4,Phase 3,Phase 2,Phase 1 83799-24-0 3348
23
Triamcinolone Approved, Vet_approved Phase 4,Phase 3 124-94-7 31307
24
Adenosine Approved, Investigational Phase 4 58-61-7 60961
25
Doxazosin Approved Phase 4 74191-85-8 3157
26
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2 51-43-4 5816
27
Diphenhydramine Approved Phase 4,Phase 3,Phase 1 58-73-1, 147-24-0 3100
28
Promethazine Approved Phase 4,Phase 3,Phase 1 60-87-7 4927
29
Ethanol Approved Phase 4,Phase 2,Phase 1 64-17-5 702
30
Glycerol Approved, Experimental Phase 4,Phase 3,Phase 1,Phase 2 56-81-5 753
31
Prazosin Approved Phase 4 19216-56-9 4893
32
Theophylline Approved Phase 4,Phase 2 58-55-9 2153
33
Tranilast Approved, Investigational Phase 4 53902-12-8 93543
34
Pimecrolimus Approved, Investigational Phase 4 137071-32-0 6447131 17753757
35
Tacrolimus Approved, Investigational Phase 4 104987-11-3 445643 439492
36
Cholecalciferol Approved, Nutraceutical Phase 4,Phase 2,Phase 3 67-97-0 6221 10883523 5280795
37
Ergocalciferol Approved, Nutraceutical Phase 4,Phase 3,Phase 2 50-14-6 5280793
38 Histamine Antagonists Phase 4,Phase 3,Phase 2,Phase 1
39 Histamine H1 Antagonists Phase 4,Phase 3,Phase 2,Phase 1
40
Histamine Phosphate Phase 4,Phase 3,Phase 2,Phase 1 51-74-1 65513
41 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1
42 Vaccines Phase 4,Phase 3,Phase 2,Phase 1
43 Antipruritics Phase 4,Phase 3,Phase 2,Phase 1
44 Dermatologic Agents Phase 4,Phase 3,Phase 2,Phase 1
45 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1
46 Anti-Allergic Agents Phase 4,Phase 3,Phase 2,Phase 1
47 Anti-Asthmatic Agents Phase 4,Phase 3,Phase 2,Phase 1
48 Histamine H1 Antagonists, Non-Sedating Phase 4,Phase 3,Phase 2,Phase 1
49 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
50 Hormones Phase 4,Phase 3,Phase 2,Phase 1

Interventional clinical trials:

(show top 50) (show all 994)
id Name Status NCT ID Phase
1 Immunological Mechanisms of Oralair® in Patients With Seasonal Allergic Rhinitis Unknown status NCT02014623 Phase 4
2 Efficacy of Allergen Immunotherapy for Allergic Rhinitis in Thais Unknown status NCT01115595 Phase 4
3 Comparative Study of Sinol and Sinol-M in Patients With Congestion Due to Allergic Rhinitis Unknown status NCT00825656 Phase 4
4 Assessment of Sublingual Immunotherapy in Children Allergic to House Dust Mites Unknown status NCT01052610 Phase 4
5 Comparison of the Effect of Montelukast and Cetirizine on Allergic Inflammation in Children With Allergic Rhinitis Unknown status NCT00488176 Phase 4
6 The Relationship Between Gastroesophageal Reflux and Pediatric Rhinitis: Significance of Pale/Blue Colored Turbinate Unknown status NCT02278081 Phase 4
7 Singulair Use in Non-Allergic Rhinitis Eosinophil Syndrome (NARES) Unknown status NCT00406094 Phase 4
8 Cosalin® Monotherapy Versus Cosalin® and Xarlin® Combination Therapy Unknown status NCT01062139 Phase 4
9 Nasal Budesonide in Children With Rhinitis and/or Mild Obstructive Sleep Apnea Syndrome Unknown status NCT00560586 Phase 4
10 POLlinosis and Exhaled Breath Temperature Unknown status NCT01785394 Phase 4
11 Comparison of Effectiveness and Safety of Sublingual Immunotherapy in Children With Allergic Rhinitis Completed NCT00698594 Phase 4
12 Sunovion Growth Study Pediatric Subjects With Mild Asthma & Allergic Rhinitis Completed NCT01550471 Phase 4
13 Anti-inflammatory H1 Antihistamines Allergic Rhinitis Completed NCT02507635 Phase 4
14 Quality of Life in Patients With Allergic Rhinitis: Clinical Trial With Bilastine or Loratadine Completed NCT02513290 Phase 4
15 Effectiveness of Oxymetazoline Added on Nasal Steroid in Rhinitis With Persistent Nasal Obstruction Completed NCT01847131 Phase 4
16 Efficacy & Safety of Loratadine-Betamethasone Oral Solution for Treatment of Severe Perennial Allergic Rhinitis in Children (Study P03428) Completed NCT00963573 Phase 4
17 Efficacy and Safety of Lectranal® in Treatment of Seasonal Allergic Rhinitis Symptoms Completed NCT00460538 Phase 4
18 Assessment of Intranasal Steroids in Allergic Rhinitis When Used Alone or in Combination With an Oral Antihistamine (Study P03270) Completed NCT00834119 Phase 4
19 A Clinical Study To Test A Nasal Spray (Fluticasone Furoate Nasal Spray) For The Treatment Of Perennial (Year-round) Allergic Rhinitis Completed NCT00609674 Phase 4
20 Comparison of Olopatadine 0.6% and Fluticasone Proprionate 50mcg Nasal Sprays in a Two Week Seasonal Allergic Rhinitis Trial Completed NCT00691665 Phase 4
21 Levocetirizine 5 mg: Reduction of Symptoms, Airway Resistance and Sleep Impairment in Persistent Allergic Rhinitis Completed NCT00355771 Phase 4
22 Montelukast in Mild Asthmatic Children With Allergic Rhinitis (0476-367) Completed NCT00442559 Phase 4
23 Montelukast and Fexofenadine Versus Montelukast and Levocetrizine Combination in Allergic Rhinitis Completed NCT02551536 Phase 4
24 Study of Triamcinolone Acetonide on the Growth Velocity of Children, Ages 3 to 9, With Perennial Allergic Rhinitis (PAR) Completed NCT00449072 Phase 4
25 POPULAR (Preference Of Patient Using Levocetirizine in Allergic Rhinitis) Completed NCT00160537 Phase 4
26 Efficacy and Tolerability of a Topical Microemulsion in Patients With Allergic Rhinitis Due to Sensitization to Pollen Completed NCT01478425 Phase 4
27 To Evaluate Adenosine Monophosphate and Allergen Challenge in Allergic Rhinitis Completed NCT00679250 Phase 4
28 Effectiveness of Individualized Homeopathic Treatment in Perennial Allergic Rhinitis Completed NCT00822406 Phase 4
29 A Phase-IV, Open-label Study to Evaluate Safety/Tolerability of Once-daily AVAMYS (TM) Aqueous Nasal Spray 110mcg Among Vietnamese Adult Patients With Established Perennial Allergic Rhinitis Completed NCT01270958 Phase 4
30 A Clinical Study With Fluticasone Furoate Nasal Spray And Vehicle Placebo For The Treatment Of Perennial (Year-round) Allergic Rhinitis Completed NCT00682643 Phase 4
31 ATAREAL (Antihistamine Treatment for Allergic Rhinitis in Real Life) Completed NCT00160680 Phase 4
32 Children, Perennial Allergic Rhinitis (PAR), l-t Growth Completed NCT00641212 Phase 4
33 Investigation of the Efficacy and Safety of Concomitant Administration of Ciclesonide Nasal Spray and Azelastine Nasal Spray in Patients (18 Years or Older) With Perennial Allergic Rhinitis (PAR) Not Adequately Controlled on an Intranasal Corticosteroid o Completed NCT00806754 Phase 4
34 The Role of Montelukast in Rhinitis and Sleep Completed NCT00590772 Phase 4
35 A Randomized, Placebo Controlled Study to Determine the Efficacy and Speed of a Nasal Spray in Allergen Induced Seasonal Allergic Rhinitis Completed NCT00561717 Phase 4
36 Fluticasone and Salmeterol in Allergic Rhinitis Completed NCT01388595 Phase 4
37 Allergic Rhinitis Changes the Sinus Microbiome Completed NCT01852513 Phase 4
38 A Study Evaluating the Efficacy and Impact on Health-related Quality of Life of Levocetirizine in Adults With Seasonal Allergic Rhinitis Completed NCT00621959 Phase 4
39 A Study Evaluating the Efficacy and Impact on Health-related Quality of Life of Levocetirizine in Adults With Seasonal Allergic Rhinitis Completed NCT00653224 Phase 4
40 Evaluation of Efficacy and Safety of Levocetirizine to Subjects With Perennial Allergic Rhinitis to House Dust Mites Completed NCT00521131 Phase 4
41 Intranasal Steroids and Oxymetazoline in Allergic Rhinitis Completed NCT00584987 Phase 4
42 Steroid Sparing Effect of Nasal Corticosteroid In Asthma And Rhinitis Completed NCT00903227 Phase 4
43 Alpha-Blockers in Allergic Rhinitis (MAN 01) Completed NCT01946035 Phase 4
44 Effects of Long-Term Treatment With Nasally Inhaled Triamcinolone Acetonide in Children With Allergic Rhinitis Completed NCT00189449 Phase 4
45 Nasal Budesonide Efficacy on Nasal FeNO in Children With Allergic Rhinitis Completed NCT02409563 Phase 4
46 Comparison of the Effects of Nasal Steroids and Montelukast on Olfactory Functions in Patients With Allergic Rhinitis Completed NCT02565212 Phase 4
47 Safety of PATANASE Nasal Spray in Patients With Perennial Allergic Rhinitis Completed NCT00789555 Phase 4
48 A Study of Onset of Action of Loratadine and Fexofenadine in Participants With Seasonal Allergic Rhinitis (P08712) Completed NCT01469234 Phase 4
49 Evaluation of the Sensory Attributes of Olopatadine 0.6% and Azelastine 137mcg Nasal Sprays in Patients w/Allergic Rhinitis Completed NCT00772304 Phase 4
50 Levocetirizine Effect on Nasal Nitric Oxide and Nasal Eosinophils in Subjects With Perennial Allergic Rhinitis Completed NCT00894231 Phase 4

Search NIH Clinical Center for Rhinitis

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: rhinitis

Genetic Tests for Rhinitis

Genetic tests related to Rhinitis:

id Genetic test Affiliating Genes
1 Rhinitis 29

Anatomical Context for Rhinitis

MalaCards organs/tissues related to Rhinitis:

39
Testes, Skin, T Cells, Neutrophil, Brain, Lung, B Cells

Publications for Rhinitis

Articles related to Rhinitis:

(show top 50) (show all 2291)
id Title Authors Year
1
Effects of CPAP in patients with obstructive apnoea: is the presence of allergic rhinitis relevant? ( 28493047 )
2017
2
Allergic Rhinitis in Preschool Children and the Clinical Utility of FeNO. ( 28497918 )
2017
3
EXPERIMENTAL EVIDENCES FOR LOCAL ALLERGIC RHINITIS. ( 28515398 )
2017
4
Effect of nasal allergen challenge in allergic rhinitis on mitochondrial function of peripheral blood mononuclear cells. ( 28073613 )
2017
5
Allergen immunotherapy for the treatment of allergic rhinitis and/or asthma: an umbrella review. ( 28495938 )
2017
6
Allergen immunotherapy in allergic rhinitis: Current use and future trends. ( 28532268 )
2017
7
Associations of single nucleotide polymorphisms of PTPN22 and Ctla4 genes with the risk of allergic rhinitis in a Chinese Han population. ( 27888068 )
2017
8
Basophil activation test for inhalant allergens in pediatric patients with allergic rhinitis. ( 28483235 )
2017
9
Broad Th2 neutralization and anti-inflammatory action of pentosan polysulfate sodium in experimental allergic rhinitis. ( 28497614 )
2017
10
The pharmacotherapy preferred by doctors in treatment of patients diagnosed with asthma or chronic obstructive pulmonary disease or allergic rhinitis and concomitant diseases: an epidemiological analysis. ( 28507495 )
2017
11
PHENOTYPE OF ALLERGIC RHINITIS AND RHINOSINUSITIS. ( 28515393 )
2017
12
Effect of the external nasal dilator on adolescent athleteswith and without allergic rhinitis. ( 28483221 )
2017
13
T-helper 2 cytokine-induced heat shock protein 70 secretion and its potential association with allergic rhinitis. ( 28054753 )
2017
14
Regional Difference of Causative Pollen in Children with Allergic Rhinitis. ( 28480649 )
2017
15
Management of allergic rhinitis in the era of effective over-the-counter treatments. ( 28532204 )
2017
16
The role of vitamin D in allergic rhinitis. ( 28487837 )
2017
17
Self-assessment of Allergic Rhinitis and Asthma (SACRA) Questionnaire-based Allergic Rhinitis Treatment Improves Asthma Control in Asthmatic Patients with Allergic Rhinitis. ( 28049997 )
2017
18
Kinetic oscillatory stimulation of nasal mucosa in non-allergic rhinitis: comparison of patient self-administration and caregiver administration regarding pain and treatment effect. A randomized clinical trial. ( 28498078 )
2017
19
Self-Reported Allergic Rhinitis and/or Allergic Conjunctivitis Associate with IL13 rs20541 Polymorphism in Finnish Adult Asthma Patients. ( 28273659 )
2017
20
Pilot study of mobile phone technology in allergic rhinitis in European countries. The MASK-rhinitis study. ( 28072463 )
2017
21
Severity of Nasal Inflammatory Disease Questionnaire for Canine Idiopathic Rhinitis Control: Instrument Development and Initial Validity Evidence. ( 28019044 )
2017
22
Strain Differences in a Murine Model of Air Pollutant-induced Nonatopic Asthma and Rhinitis. ( 28068894 )
2017
23
Allergen Immunotherapy for a Teenager with Seasonal Allergic Rhinitis Due to Grass Pollen: Subcutaneous or Sublingual Route? ( 28065341 )
2017
24
Mapping and comparing bacterial microbiota in the sinonasal cavity of healthy, allergic rhinitis, and chronic rhinosinusitis subjects. ( 28481057 )
2017
25
Effectiveness of quercetin in an experimental rat model of allergic rhinitis. ( 28493194 )
2017
26
"Allergic mood" - Depressive and anxiety symptoms in patients with seasonal allergic rhinitis (SAR) and their association to inflammatory, endocrine, and allergic markers. ( 28495610 )
2017
27
Role of Interleukin-17A on the Chemotactic Responses to CCL7 in a Murine Allergic Rhinitis Model. ( 28046055 )
2017
28
Non-Allergic Rhinitis: Position paper of the European Academy of Allergology and Clinical Immunology. ( 28474799 )
2017
29
A functional variant of miRNA-149 confers risk for allergic rhinitis and comorbid asthma in Chinese children. ( 28181414 )
2017
30
Association of pediatric allergic rhinitis with the ratings of attention-deficit/hyperactivity disorder. ( 28490400 )
2017
31
Correlation between Serum Osteopontin and miR-181a Levels in Allergic Rhinitis Children. ( 27199509 )
2016
32
Badly Behaving Noses in Children: Rhinitis, Sinusitis, or Neither? ( 27841920 )
2016
33
The Prevalence of Allergic Rhinitis, Eczema and Asthma in Students of Guidance Schools in Mazandaran Province, Iran. ( 28028401 )
2016
34
USE OF COMPUTED TOMOGRAPHY FOR INVESTIGATION OF RHINITIS AND SINUSITIS IN A GREATER RHEA (RHEA AMERICANA). ( 28080910 )
2016
35
Semi-depot house-dust mite allergen extract for Chinese with allergic rhinitis and asthma. ( 27216351 )
2016
36
Suppression of neuropeptide production by quercetin in allergic rhinitis model rats. ( 27207147 )
2016
37
Allergic rhinitis, rhinoconjunctivitis and eczema: Prevalence and associated factors in children. ( 27663282 )
2016
38
Vitamin D levels in allergic rhinitis: a systematic review and meta-analysis. ( 27188226 )
2016
39
A Nonsynonymous FCER1B SNP is Associated with Risk of Developing Allergic Rhinitis and with IgE Levels. ( 26792385 )
2016
40
Long-term safety of replication-defective smallpox vaccine (MVA-BN) in atopic eczema and allergic rhinitis. ( 27357167 )
2016
41
Gene polymorphisms of interleukin-10 and transforming growth factor beta in allergic rhinitis. ( 26316419 )
2016
42
Genetic variations in interleukin-12B in allergic rhinitis. ( 26663019 )
2016
43
Does adenoid hypertrophy affect disease severity in children with allergic rhinitis? ( 27405740 )
2016
44
Health care resource use and associated costs among patients with seasonal versus perennial allergic rhinitis. ( 27657517 )
2016
45
Local allergic rhinitis: entopy or spontaneous response? ( 27980704 )
2016
46
MODIFIER FACTORS OF ALLERGIC RHINITIS AND EOSINOPHILIC RHINOSINUSITS: CLINICAL APPLICATION. ( 27193924 )
2016
47
Utility of the Atopy Patch Test in the Diagnosis of Allergic Rhinitis. ( 27429944 )
2016
48
Local allergic rhinitis in children: Novel diagnostic features and potential biomarkers. ( 27657898 )
2016
49
Effects of omalizumab therapy on allergic rhinitis: a pilot study. ( 28051241 )
2016
50
Dust Mite-Induced Perennial Allergic Rhinitis in Pediatric Patients and Sublingual Immunotherapy. ( 27665384 )
2016

Variations for Rhinitis

Expression for Rhinitis

Search GEO for disease gene expression data for Rhinitis.

Pathways for Rhinitis

Pathways related to Rhinitis according to GeneCards Suite gene sharing:

(show all 38)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.97 CCL11 CCL5 CXCL8 EPX ICAM1 IGHE
2
Show member pathways
13.63 CCL11 CCL5 CXCL8 IL13 IL4 IL4R
3
Show member pathways
13.5 CCL11 CCL5 CXCL8 ICAM1 IL13 IL4
4
Show member pathways
13.38 CCL11 CCL5 CXCL8 IL13 IL4 IL4R
5
Show member pathways
13.25 CCL11 CCL5 CXCL8 IL13 IL4 IL4R
6
Show member pathways
13.25 CCL11 CCL5 CXCL8 ICAM1 IGHE IL13
7
Show member pathways
12.8 CCL11 CXCL8 EPX ICAM1 IL13 IL4
8
Show member pathways
12.75 CCL5 CXCL8 ICAM1 IL13 IL4
9
Show member pathways
12.34 CCL11 HRH1 IGHE IL4 IL4R
10
Show member pathways
12.29 CCL11 CCL5 CXCL8 ICAM1
11
Show member pathways
12.27 CCL11 CXCL8 IL13 IL4 IL5
12
Show member pathways
12.18 IL13 IL4 IL4R IL5
13 12.14 CXCL8 IL13 NGF NR3C1
14
Show member pathways
12.12 CXCL8 IL13 IL4 IL5
15 11.84 CXCL8 ICAM1 VCAM1
16 11.83 IL4 IL4R IL5
17 11.82 CXCL8 ICAM1 VCAM1
18 11.79 CCL5 CXCL8 ICAM1
19 11.73 IL13 IL4 IL5
20
Show member pathways
11.71 CXCL8 IL4 IL5
21 11.66 ICAM1 IL4 IL5 VCAM1
22 11.63 CCL11 IGHE IL4 IL4R IL5
23
Show member pathways
11.6 CXCL8 ICAM1 NR3C1 VCAM1
24 11.49 CXCL8 ICAM1 VCAM1
25 11.44 CXCL8 ICAM1 VCAM1
26 11.43 CCL11 CCL5 CXCL8 IL13 IL4 IL5
27 11.41 CCL5 CXCL8 ICAM1 IL13 IL4
28 11.41 CXCL8 ICAM1 IL13 IL4 IL5 NR3C1
29 11.33 CCL11 IL13 IL4 IL4R IL5
30 11.33 CCL11 CXCL8 ICAM1 IGHE IL13 IL4
31 11.29 IL4 IL4R IL5
32 11.27 IL13 IL4 IL5
33 11.23 IL13 IL4 IL5
34 11.18 CCL11 CCL5 CXCL8 IL13 IL4 IL5
35 11.14 IL13 IL4 IL5
36 11.02 IL4 IL4R VCAM1
37 10.88 ICAM1 VCAM1
38 10.85 IL13 IL4 IL4R IL5

GO Terms for Rhinitis

Cellular components related to Rhinitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.77 CCL11 CCL5 CXCL8 EPX IGHE IL13
2 external side of plasma membrane GO:0009897 9.55 ICAM1 IGHE IL13 IL4 VCAM1
3 extracellular space GO:0005615 9.44 CCL11 CCL5 CXCL8 EPX ICAM1 IL13

Biological processes related to Rhinitis according to GeneCards Suite gene sharing:

(show all 25)
id Name GO ID Score Top Affiliating Genes
1 response to ethanol GO:0045471 9.81 ICAM1 IL13 IL4 VCAM1
2 chemotaxis GO:0006935 9.8 CCL11 CCL5 CXCL8 CYSLTR1 IL4
3 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 9.79 ICAM1 IL4 IL5
4 chemokine-mediated signaling pathway GO:0070098 9.77 CCL11 CCL5 CXCL8
5 neutrophil chemotaxis GO:0030593 9.75 CCL11 CCL5 CXCL8
6 positive regulation of T cell proliferation GO:0042102 9.74 CCL5 IL4 VCAM1
7 cellular response to interferon-gamma GO:0071346 9.73 CCL11 CCL5 ICAM1
8 cellular response to interleukin-1 GO:0071347 9.73 CCL11 CCL5 CXCL8 ICAM1
9 positive regulation of B cell proliferation GO:0030890 9.7 IL13 IL4 IL5
10 negative regulation of endothelial cell apoptotic process GO:2000352 9.65 ICAM1 IL13 IL4
11 cellular response to tumor necrosis factor GO:0071356 9.65 CCL11 CCL5 CXCL8 ICAM1 VCAM1
12 leukocyte cell-cell adhesion GO:0007159 9.63 CCL5 ICAM1 VCAM1
13 microglial cell activation GO:0001774 9.62 IL13 IL4
14 positive regulation of macrophage activation GO:0043032 9.61 IL13 IL4R
15 negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 9.61 CCL5 CXCL8
16 chronic inflammatory response GO:0002544 9.6 CCL11 VCAM1
17 neutrophil activation GO:0042119 9.58 CCL5 CXCL8
18 membrane to membrane docking GO:0022614 9.55 ICAM1 VCAM1
19 regulation of proton transport GO:0010155 9.54 IL13 IL4
20 positive regulation of mast cell degranulation GO:0043306 9.54 IL13 IL4 IL4R
21 eosinophil chemotaxis GO:0048245 9.5 CCL11 CCL5 HRH1
22 inflammatory response GO:0006954 9.5 CCL11 CCL5 CXCL8 HRH1 IL13 IL5
23 negative regulation of complement-dependent cytotoxicity GO:1903660 9.49 IL13 IL4
24 positive regulation of immunoglobulin production GO:0002639 9.33 IL13 IL4 IL4R
25 immune response GO:0006955 9.23 CCL11 CCL5 CXCL8 IGHE IL13 IL4

Molecular functions related to Rhinitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 chemokine activity GO:0008009 9.13 CCL11 CCL5 CXCL8
2 cytokine activity GO:0005125 9.1 CCL11 CCL5 CXCL8 IL13 IL4 IL5

Sources for Rhinitis

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