Rhinotracheitis malady

Disease Ontology: An upper respiratory tract disease involving inflammation of the nasal cavities and trachea caused by feline herpesvirus 1, of the family herpesviridae in cats and especially young kittens that is characterized by sneezing, conjunctivitis with discharge, and nasal discharges.⁶

MalaCards: Rhinotracheitis, also known as feline viral rhinotracheitis, is related to mouth disease and dermatitis. An important gene associated with Rhinotracheitis is BCL2L15 (BCL2-like 15). The drugs zinc (as sulfate) and sodium ascorbate and the compound lipid have been mentioned in the context of this disorder. Affiliated tissues include trachea.

rhinotracheitis 6 8 43 feline viral rhinotracheitis 6 43 feline influenza 6

feline coryza 6 common cold 43 influenza 43

Diseases related to rhinotracheitis by text searches and GeneDecks gene sharing:

(show top 50)    (show all 83)

id	Related Disease	Score	Top Affiliating Genes
1	mouth disease	12.2	MAFF, GSG2
2	dermatitis	11.7	PI3, BCL2L15, DARC
3	haemophilus influenzae	11.5
4	avian influenza	9.9
5	common cold	9.9
6	swine influenza	9.3
7	pneumonia	8.8
8	immunodeficiency	7.5
9	meningitis	7.2
10	hepatitis	6.9
11	otitis media	6.9
12	influenza	6.7
13	nasopharyngitis	6.7
14	cystic fibrosis	6.6
15	fibrosis	6.6
16	leukemia	6.6
17	herpes simplex	6.2
18	influenza myositis	6.2
19	sepsis	6.2
20	bronchitis	6.2
21	epiglottitis	6.2
22	melanoma	5.8
23	pulmonary disease	5.8
24	viral infectious disease	5.8
25	asthma	5.8
26	blindness	5.8
27	cold-induced autoinflammatory syndrome	5.8
28	cold-induced autoinflammatory syndrome, familial	5.8
29	acute lymphoblastic leukemia	5.7
30	arthritis	5.7
31	atherosclerosis	5.7
32	bronchial asthma	5.7
33	cervicitis	5.7
34	lymphoblastic leukemia	5.7
35	rheumatoid arthritis	5.7
36	schizophrenia	5.7
37	stomatitis	5.7
38	b-cell lymphomas	4.8
39	hepatitis b	4.8
40	retinitis	4.8
41	bacterial conjunctivitis	4.8
42	haverhill fever	4.8
43	reye syndrome	4.8
44	bronchiolitis	4.8
45	icos deficiency	4.8
46	sinusitis	4.8
47	chronic obstructive pulmonary disease	4.8
48	mumps	4.8
49	septic abortion	4.8
50	conjunctivitis	4.8

Approved drugs:

Drug clinical trials:

Inferred drug relations via UMLS/NDF-RT:

^43 28 ascorbic acid, ascorbic acid pwdr [va product], guaifenesin, phenylpropanolamine, phenylpropanolamine hydrochloride, pseudoephedrine, pseudoephedrine hydrochloride, pseudoephedrine sulfate, sodium ascorbate, zinc (as gluconate), zinc (as sulfate), zinc acetate, zinc chloride, zinc gluconate, zinc sulfate, zinc sulfate pwdr [va product]

MalaCards organs/tissues related to rhinotracheitis:

²²

Genes related to rhinotracheitis according to GeneCards:

id	Symbol	Description	Score	GeneCards Section Context
1	BCL2L15	BCL2-like 15	11.0
2	CATSPER1	cation channel, sperm associated 1	11.0	Disorders
3	GSG2	germ cell associated 2 (haspin)	11.0
4	LST1	leukocyte specific transcript 1	11.0
5	MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)	11.0
6	PI3	peptidase inhibitor 3, skin-derived	11.0
7	DARC	Duffy blood group, chemokine receptor	11.0
8	TERT	telomerase reverse transcriptase	11.0

Compounds related to rhinotracheitis according to GeneDecks:

id	Compound	Score	Top Affiliating Genes
1	lipid32	8.2	PI3, BCL2L15, TERT, DARC