MCID: RGH001
MIFTS: 44

Right Bundle Branch Block malady

Category: Cardiovascular diseases

Aliases & Classifications for Right Bundle Branch Block

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Aliases & Descriptions for Right Bundle Branch Block:

Name: Right Bundle Branch Block 11 50 13 68
Right Bundle Branch Block with Left Posterior Fascicular Block 11
 
Right-Bundle Branch Block 27

Classifications:



External Ids:

Disease Ontology11 DOID:13209
SNOMED-CT62 46319007
ICD9CM32 426.51

Summaries for Right Bundle Branch Block

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Wikipedia:71 A right bundle branch block (RBBB) is a heart block in the electrical conduction system. more...

MalaCards based summary: Right Bundle Branch Block, also known as right bundle branch block with left posterior fascicular block, is related to heart block, progressive, type ia and rheumatic heart disease. An important gene associated with Right Bundle Branch Block is SCN5A (Sodium Voltage-Gated Channel Alpha Subunit 5), and among its related pathways are Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways and NCAM1 interactions. Affiliated tissues include heart, testes and atrioventricular node, and related mouse phenotype cardiovascular system.

Related Diseases for Right Bundle Branch Block

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Diseases related to Right Bundle Branch Block via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 78)
idRelated DiseaseScoreTop Affiliating Genes
1heart block, progressive, type ia32.3CACNA1C, SCN5A
2rheumatic heart disease29.8HCN4, SCN5A
3progressive familial heart block, type ib11.9
4brugada syndrome11.6
5brugada syndrome 911.1
6brugada syndrome 211.1
7brugada syndrome 111.1
8brugada syndrome 411.1
9brugada syndrome 611.1
10brugada syndrome 711.1
11brugada syndrome 311.1
12brugada syndrome 811.1
13brugada syndrome 511.1
14myocardial infarction10.8
15acute myocardial infarction10.6
16tetralogy of fallot10.4
17cardiomyopathy10.4
18ventricular septal defect10.3
19atrial fibrillation10.3
20pulmonary embolism10.3
21developmental dysplasia of the hip 210.2GPD1L, SCN5A
22arrhythmogenic right ventricular cardiomyopathy10.2
23atrioventricular block10.2
24camurati-engelmann disease10.2SCN1B, SCN5A
25patel bixler syndrome10.2CACNA1C, SCN5A
26heart disease10.2
27sudden cardiac death10.2
28aneurysm10.2
29wolff-parkinson-white syndrome10.2
30artery disease10.2
31micturation-induced seizures10.1HCN4, SCN5A
32isolated encephalocele10.1CACNA1C, SCN5A
33sinoatrial node disease10.1DSG4, SCN5A
34fatal infantile encephalomyopathy10.1SCN1B, SCN5A, TRPM4
35lipodystrophy, familial partial, type 510.1HCN4, SCN5A
36combined oxidative phosphorylation deficiency 1710.1SCN1B, SCN5A, TRPM4
37fanconi anemia complementation group r10.1SCN1B, SCN5A, TRPM4
38keppen-lubinsky syndrome10.1CACNA1C, SCN5A
39short qt syndrome 210.1CACNA1C, SCN5A
40coronary artery disease10.1
41congestive heart failure10.1
42second-degree atrioventricular block10.1
43inferior myocardial infarction10.1
44anteroseptal myocardial infarction10.1
45atrial septal aneurysm10.1
46third-degree atrioventricular block10.1HCN4, SCN5A, TRPM4
47tricuspid valve disease10.0DSG4, HCN4
48retinal cone dystrophy 410.0CACNA1C, CACNB2
49squamous cell papilloma10.0HCN4, SCN5A
50chagas disease10.0

Comorbidity relations with Right Bundle Branch Block via Phenotypic Disease Network (PDN):

(show all 30)
Atrioventricular BlockBenign Essential Hypertension
Chronic Myocardial IschemiaChronic Pulmonary Heart Disease
Deficiency AnemiaFirst-Degree Atrioventricular Block
Hypertension, EssentialIntermediate Coronary Syndrome
Ischemic Heart DiseaseLeft Bundle Branch Hemiblock
Left Ventricular Outflow Tract ObstructionMitral Valve Disease
Mobitz Type Ii Atrioventricular BlockPulmonary Hypertension, Familial Primary, 1, with or Without Hht
Acute CystitisBronchitis
EsophagitisFamilial Atrial Fibrillation
Generalized AtherosclerosisHeart Conduction Disease
Heart DiseasePeripheral Vascular Disease
Postinflammatory Pulmonary FibrosisProgressive Familial Heart Block
Prostatic HypertrophyRespiratory Failure
Sinoatrial Node DiseaseTransient Cerebral Ischemia
Third-Degree Atrioventricular BlockTricuspid Valve Disease

Graphical network of the top 20 diseases related to Right Bundle Branch Block:



Diseases related to right bundle branch block

Symptoms & Phenotypes for Right Bundle Branch Block

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MGI Mouse Phenotypes related to Right Bundle Branch Block according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053856.9CACNA1C, CACNB2, HCN4, KCND3, SCN3B, SCN5A

Drugs & Therapeutics for Right Bundle Branch Block

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Drugs for Right Bundle Branch Block (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 23)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
TolvaptanapprovedPhase 390150683-30-0216237
Synonyms:
( -)-4'-((7-Chloro-2,3,4,5-tetrahydro-5-hydroxy-1H-1-benzazepin-1-yl)carbonyl)-o-tolu-m-toluidide
150683-30-0
7-Chloro-5-hydroxy-1-(2-methyl-4-(2-methylbenzoylamino)benzoyl)2,3,4,5-tetrahydro-1H-1-benzazepine
AC1L50C9
C116664
CHEBI:327437
CHEMBL344159
CID216237
 
L001628
N-[4-(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl)-3-methylphenyl]-2-methylbenzamide
OPC 41061
OPC-41061
PDSP1_001738
PDSP2_001721
Samsca
Tolvaptan
UNII-21G72T1950
benzazepine derivative, 32
2VasopressinsPhase 3294
3Arginine VasopressinPhase 3299
4Natriuretic AgentsPhase 31697
5HormonesPhase 314415
6
Pyrimethamineapproved, vet_approvedPhase 215758-14-04993
Synonyms:
2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine
2,4-Diamino-5-(P-chlorophenyl)-6-ethylpyrimidine
2,4-Diamino-5-(p-chlorophenyl)-6-ethylpyrimidine
2,4-Diamino-5-chlorophenyl-6-ethylpyrimidine
46706_FLUKA
46706_RIEDEL
4753 R.P.
4753 r.p
5-(4'-Chlorophenyl)-2,4-diamino-6-ethylpyrimidine
5-(4-CHLORO-PHENYL)-6-ETHYL-PYRIMIDINE-2,4-DIAMINE
5-(4-CHLOROPHENYL)-6-ETHYL-2,4-PYRIMIDINEDIAMINE
5-(4-Chlorophenyl)-6-ethyl-2,4-diaminopyrimidine
5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidi nediamine
5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidinediamine
5-(4-chlorophenyl)-2,4-diamino-6-ethylpyrimidine
5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine
5-(p-chlorophenyl)-6-ethyl-2,4-diaminopyrimidine
5-[4-Chlorophenyl]-6-ethyl-2,4-pyrimidinediamine
58-14-0
AB00052084
AC-7879
AC1L1JDI
AI3-25005
AZT + Pyrimethamine combination
Aventis Brand of Pyrimethamine
BIDD:GT0149
BIDD:PXR0173
BPBio1_000147
BRD-K88429204-001-05-4
BRN 0219864
BSPBio_000133
BSPBio_003282
BW 50-63
BW 5063
C07391
C12H13ClN4
CAS-58-14-0
CCRIS 546
CD
CHEBI:8673
CHEMBL36
CID4993
CP6
CPD000058714
CRL-8131 & Pyrimethamine
CRL-8142 & Pyrimethamine
Chloridin
Chloridine
Chloridyn
D00488
D011739
DB00205
Darachlor
Daraclor
Darapram
Daraprim
Daraprim (TN)
Daraprime
Daraprin
Diaminopyritamin
Disulone
DivK1c_000652
EINECS 200-364-2
EXR-101
Erbaprelina
Ethylpyrimidine
Fansidar
Fansidar (Pyrimethamine/Sulfadoxine)
Glaxo Wellcome Brand of Pyrimethamine
GlaxoSmithKline Brand of Pyrimethamine
HMS1568G15
HMS1920N12
HMS2092E13
HMS502A14
IDI1_000652
KBio1_000652
KBio2_001386
KBio2_003954
 
KBio2_006522
KBio3_002502
KBioGR_001007
KBioSS_001386
Khloridin
L000713
LS-238
Lactoferrin B & Pyrimethamine
Lactoferrin H & Pyrimethamine
MCB-3837
MLS000028606
MLS001148621
MLS002454446
MLS002701881
Malacid
Malocid
Malocide
Maloprim
MolPort-001-783-655
NCGC00016256-01
NCGC00016256-02
NCGC00023188-03
NCGC00023188-04
NCGC00023188-05
NCGC00023188-06
NCGC00023188-07
NCI-C01683
NCI60_002604
NCIOpen2_008313
NINDS_000652
NSC 3061
NSC-3061
NSC3061
Oxaquin
Pirimecidan
Pirimetamin
Pirimetamina
Pirimetamina [INN-Spanish]
Pirimetamina [Spanish]
Prestwick0_000037
Prestwick1_000037
Prestwick2_000037
Prestwick3_000037
Prestwick_504
Primethamine
Pyremethamine
Pyrimethamin
Pyrimethamine (JAN/USP/INN)
Pyrimethamine (Pyr)
Pyrimethamine Hcl
Pyrimethamine [USAN:INN:BAN:JAN]
Pyrimethaminum
Pyrimethaminum [INN-Latin]
RP 4753
S2006_Selleck
SAM002554921
SMR000058714
SPBio_000672
SPBio_002054
SPECTRUM1500520
Spectrum2_000886
Spectrum3_001701
Spectrum4_000494
Spectrum5_001447
Spectrum_000906
TCMDC-123831
TCMDC-125860
Tindurin
Tindurine
Tinduring
UNII-Z3614QOX8W
WLN: T6N CNJ BZ DZ ER DG& F2
WR 2978
Wellcome Brand of Pyrimethamine
ZINC00057464
m alocid
nchembio.215-comp13
nchembio.87-comp22
pyrimethamine
7
SulfadoxineapprovedPhase 21322447-57-617134
Synonyms:
2447-57-6
4-Amino-N-(5,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide
4-Sulfanilamido-5,6-dimethoxypyrimidine
4-amino-N-(5,6-dimethoxypyrimidin-4-yl)benzenesulfonamide
4-amino-N-[5,6-bis(methyloxy)pyrimidin-4-yl]benzenesulfonamide
46810_RIEDEL
5-25-13-00306 (Beilstein Handbook Reference)
6-(4-Aminobenzenesulfonamido)-4,5-dimethoxypyrimidine
AB00514044
AC-11921
AC1L29DT
AC1Q46GG
Ambap2447-57-6
BPBio1_001286
BRD-K55250441-001-03-1
BRN 0625453
BSPBio_001168
C07630
CAS-2447-57-6
CHEBI:9329
CHEMBL1539
CID17134
D00580
DB01299
EINECS 219-504-9
Fanasil
Fanzil
HMS1571K10
HMS2090P07
HMS2094C19
I09-0529
LS-31247
MLS002154150
MolPort-003-850-341
N'-(5,6-Dimethoxy-4-pyrimidyl)sulfanilamide
N(sup 1)-(5,6-Dimethoxy-4-pyrimidinyl)sulfanilamide
 
N1-(5,6-Dimethoxy-4-pyrimidinyl)sulfanilamide
NCGC00016612-01
NCGC00016612-02
Orthosulfin
Prestwick0_001094
Prestwick1_001094
Prestwick2_001094
Prestwick3_001094
Ro 4-4393
Ro-4-4393
S2511_Selleck
S7821_SIGMA
SMR000857259
SPBio_003054
SULFADOXINE
Sanasil: Sulfadoxine: Sulformetoxin
Solfadossina
Solfadossina [DCIT]
Sulfadoxin
Sulfadoxina
Sulfadoxina [INN-Spanish]
Sulfadoxine
Sulfadoxine (JAN/USP/INN)
Sulfadoxine [USAN:INN:BAN:JAN]
Sulfadoxinum
Sulfadoxinum [INN-Latin]
Sulformethoxine
Sulformetoxine
Sulforthomidine
Sulphadoxine
Sulphormethoxine
Sulphormetoxin
Sulphorthodimethoxine
UNII-88463U4SM5
WR 4073
WR 4873
ZINC00002094
8
leucovorinapproved, NutraceuticalPhase 2323558-05-954575, 6560146, 143
Synonyms:
(5-formyl-5,6,7,8-tetrahydropteroyl)glutamate
(6R,S)-5-Formyltetrahydrofolate
10-Formyl-7,8-dihydrofolate
10-Formyl-7,8-dihydrofolic acid
5-Formyl-5,6,7,8-tetrahydrofolate
5-Formyl-5,6,7,8-tetrahydrofolic acid
5-Formyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid
5-Formyltetrahydrofolate
5-Formyltetrahydrofolic acid
5-Formyltetrahydropteroylglutamate
5-Formyltetrahydropteroylglutamic acid
5-formyltetrahydrofolic acid
Acide folinique
Calcium citrovorum factor
Calcium folinate
Citrovorum factor
Folinate
Folinic acid
Folinic acid calcium salt
 
Folinic acid calcium salt USP27
Folinic acid-SF
L(-)-5-Formyl-5,6,7,8-tetrahydrofolic acid
L-Leucovorin
L-N-[p-[[(2-Amino-5-formyl-5,6,7,8-tetrahydro-4-hydroxy-6-pteridinyl)methyl]amino]benzoyl]-Glutamic acid
L-leucovorin
Leucal
Leucovorin calcium
Leucovorin folinic acid
Leucovorinum
Leukovorin
Levoleucovorin
N-(5-formyl-5,6,7,8-tetrahydropteroyl)-L-glutamic acid
N5-Formyl-5,6,7,8-tetrahydrofolate
N5-Formyl-5,6,7,8-tetrahydrofolic acid
N5-Formyl-THF
N5-Formyltetrahydrofolate
N5-Formyltetrahydrofolic acid
Welcovorin
Wellcovorin
folinate
9
Folic Acidapproved, nutraceutical, vet_approvedPhase 2439259-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
Folsaeure
 
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
10Vitamin B ComplexPhase 24337
11Folic Acid AntagonistsPhase 22257
12
PiperaquinePhase 21094085-31-85079497
Synonyms:
1,3-bis(1-(7-chloro-4'-quinolyl)-4'-piperazinyl)propane
1,3-bis(4-(7'-chloro-4'-quinoline)-1-piperazine)
4,4'-(propane-1,3-diyldipiperazine-4,1-diyl)bis(7-chloroquinoline)
4085-31-8
5-23-03-00072 (Beilstein Handbook Reference)
7-chloro-4-[4-[3-[4-(7-chloroquinolin-4-yl)piperazin-1-yl]propyl]piperazin-1-yl]quinoline
83764-65-2
AC1L3UA1
AC1Q3T7B
AR-1F7471
 
BRN 0905079
C29H32Cl2N6
CHEMBL303933
CID122262
FT-0082661
I06-1673
LS-142194
Piperaquinoline
Quinoline, 4,4'-(1,3-propanediyldi-4,1-piperazinediyl)bis(7-chloro- (9CI)
Quinoline, 4,4'-(1,3-propanediyldi-4,1-piperazinediyl)bis(7-chloro-)
ST51053186
piperaquine
13Renal AgentsPhase 2754
14
DihydroartemisininPhase 29571939-50-96918483
Synonyms:
(3R,5aS,6R,8aS,9R,12R,12aR)-3,6,9-trimethyldecahydro-3,12-epoxypyrano[4,3-j][1,2]benzodioxepin-10-ol
1,5,9-trimethyl-(1R,4S,5R,8S,9R,10S,12R,13R)-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-ol(Dihydroartemisinin)
71939-50-9
81496-81-3
AC-2067
AC1L32PY
AC1L9UV6
Ambotz71939-50-9
Artenimol
Artenimol (INN)
CHEBI:207229
CHEMBL25164
CID107770
 
CID456410
CID6918483
Cotecxin
D07362
D3793
Dihydroartemisinin
Dihydroartemisinine
Dihydroqinghaosu
Dihydroquinghaosu
Dihydroquinghoasu
GNF-PF-5634
JAV-110
LS-64240
VM3352
[3R-(3.alpha.,5a.beta.,6.beta.,8a.beta.,9.alpha.,10.alpha.,12.beta.,12aR*)]-Decahydro-10-hydroxy-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4.3-j]-1,2-benzodioxepin
15AntimalarialsPhase 21246
16Anti-Infective AgentsPhase 222062
17Antiparasitic AgentsPhase 22199
18Antiprotozoal AgentsPhase 22051
19Fanasil, pyrimethamine drug combinationPhase 2122
20ArtemisininsPhase 2289
21ArtemisininePhase 2289
22Vitamin B9NutraceuticalPhase 24392
23FolateNutraceuticalPhase 24392

Interventional clinical trials:

(show all 19)
idNameStatusNCT IDPhase
1Resynchronization in Paced Heart Failure Patients With Implantable Cardioverter Defibrillator (ICD) IndicationUnknown statusNCT01415024Phase 4
2Effects of Titrated Oral Tolvaptan 15-60 mg Once Daily (QD) on Cognitive and Neurological Function in Elderly Hyponatremic PatientsCompletedNCT00550459Phase 3
3MADIT ASIA Cardiac Resynchronization TrialTerminatedNCT01872234Phase 3
4Cardio‑Safety of Dihydroartemisinin‑Piperaquine and Pharmacokinetics of Piperaquine Amongst Pregnant Women in TanzaniaRecruitingNCT02909712Phase 2
5Congenital or Idiopathic Complete Right Bundle Branch Block: Physiological Significance and Molecular CharacterizationUnknown statusNCT00173342
6Prevalence of Chagas Disease in Immigrant Patients With Conduction Abnormalities on ElectrocardiogramUnknown statusNCT00453700
7Left Ventricular Function and Remodelling During Permanent PacingUnknown statusNCT00228241
8Efficacy and Safety of Multisite Cardiac Resynchronization TherapyUnknown statusNCT01966016
9Selective Coronary Vein Sampling in Left Bundle Branch Block and CRTUnknown statusNCT02396875
10Right Bundle Branch Block After Surgical Closure of Ventricular Septal DefectCompletedNCT01480908
11The Effect of Right Ventricular Pacing on Myocardial Oxidative Metabolism and EfficiencyCompletedNCT00704093
12Predicting Hypoglycaemia and Arrhythmias in the Vulnerable Patient With Diabetes and Chronic Kidney DiseaseCompletedNCT02315300
13QT Interval in Patients With Pacemaker DependencyCompletedNCT01694550
14Right Ventricular Septal Pacing in Patients With Right Bundle Branch Block and Heart Failure (The SPARK Trial)RecruitingNCT02441101
15His Bundle Pacing in Bradycardia and Heart FailureRecruitingNCT03008291
16Comparison Between Standard and Ultrasound Integrated Approach for Risk Stratification of Syncope in the Emergency DepartmentRecruitingNCT02781207
17Pacing Affects Cardiovascular Endpoints in Patients With Right Bundle-Branch Block (The PACE-RBBB Trial)TerminatedNCT01169493
18High Septal Pacing for Cardiac Resynchronization TherapyTerminatedNCT01325480Early Phase 1
19MIRACLE EF Clinical StudyTerminatedNCT01735916

Search NIH Clinical Center for Right Bundle Branch Block

Genetic Tests for Right Bundle Branch Block

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Genetic tests related to Right Bundle Branch Block:

id Genetic test Affiliating Genes
1 Right Bundle Branch Block27

Anatomical Context for Right Bundle Branch Block

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MalaCards organs/tissues related to Right Bundle Branch Block:

36
Heart, Testes, Atrioventricular node, Spinal cord

Publications for Right Bundle Branch Block

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Articles related to Right Bundle Branch Block:

(show top 50)    (show all 561)
idTitleAuthorsYear
1
Exercise left ventricular ejection fraction predicts events in right bundle branch block. (26634337)
2016
2
Right Bundle Branch Block: A Masquerader in Acute Coronary Syndrome. (27042612)
2016
3
ECG Case of the Month: IRREGULARLY IRREGULAR CARDIAC RHYTHM IN AN 87-YEAR-OLD WOMAN. MULTIFOCAL ATRIAL TACHYCARDIA; RIGHT BUNDLE BRANCH BLOCK. (26986865)
2016
4
An interventricular and right intraventricular dyssynchrony related to right bundle branch block appearance as cause of RVOT gradient decrease in a HCM patient. (26802821)
2016
5
TCT-685 Pre-existing Right Bundle-Branch Block Increases Risk of Death after Transcatheter Aortic Valve Implantation with a Balloon-Expandable Valve. (27970062)
2016
6
Prognostic Significance of Right Bundle Branch Block for Patients with Acute Myocardial Infarction: A Systematic Review and Meta-Analysis. (27017617)
2016
7
Absent right bundle branch block: Is it a clue of pre-excitation in Ebstein's anomaly? (27751284)
2016
8
Complete right bundle branch block and QRS-T discordance can be the initial clue to detect S-ICD ineligibility. (28034575)
2016
9
Transient complete right bundle branch block following right heart catheterization in children - a report of two cases. (27980554)
2016
10
Sodium channel blockade unmasked Brugada electrocardiographic pattern in a patient with complete right bundle branch block and early repolarization in the lateral leads. (27830074)
2016
11
Transient right bundle branch block in a patient with acute pulmonary embolism. (27817836)
2016
12
Clinical Characteristics, Management, and Outcomes of Acute Coronary Syndrome in Patients With Right Bundle Branch Block on Presentation. (26762726)
2016
13
Comorbidities of Chronic Complete Right Bundle Branch Block and Correlations With Coronary Angiographic Findings. (26802764)
2016
14
Right ventricular failure predicted from right bundle branch block: cardiac magnetic resonance imaging validation. (27747166)
2016
15
Postoperative right bundle branch block after closure of ventricular septal defect predicts lower peak heart rate in adulthood. (26655532)
2016
16
Right bundle branch block and SIQIII-type patterns for risk stratification in acute pulmonary embolism. (27083328)
2016
17
Right Bundle Branch Block-Like Pattern During Uncomplicated Right Ventricular Pacing and the Effect of Pacing Site. (26796192)
2016
18
Do patients with heart failure and right bundle branch block need biventricular pacing? A case of significant QRS narrowing by right ventricular pacing alone. (25464987)
2015
19
Cardiac MRI assessment of right ventricular function: impact of right bundle branch block on the evaluation of cardiac performance parameters. (26134997)
2015
20
ECG Case of the Month: Unexpected Atrioventricular Conduction in High-Grade Atrioventricular Block. Sinus rhythm; high-grade second degree atrioventricular block with a junctional escape rhythm and three capture complexes, each with right bundle branch block aberration; possible septal myocardial infarct of indeterminate age; ST-T and U wave changes suggesting hypokalemia. (25978059)
2015
21
Cardiac pacing in patients with heart failure and right bundle branch block. (25465861)
2015
22
Right Bundle Branch Block and Electromechanical Coupling of the Right Ventricle: An Echocardiographic Study. (26900418)
2015
23
Mechanism of transient resolution of chronic complete right bundle branch block following an acute anterior myocardial infarction. (26184919)
2015
24
Transient resolution of chronic right bundle branch block in the acute phase of myocardial infarction. (25528274)
2015
25
Brugada Syndrome with Early Repolarization masked by Complete Right Bundle-Branch Block. (26443792)
2015
26
The mechanism of the resolution of chronic right bundle branch block during acute myocardial infarction. (26022426)
2015
27
Comparison of left ventricular torsion and strain with biventricular pacing in patients with underlying right bundle branch block versus those with left bundle branch block. (25779616)
2015
28
Right Bundle Branch Block-Like Pattern During Ventricular Pacing: A Surface Electrocardiographic Mapping Technique to Locate the Ventricular Lead. (26118446)
2015
29
Supernormal conduction revealed by extremely late atrial extrasystole during phase 3 right bundle branch block. (26113469)
2015
30
New Right Bundle Branch Block as a Criterion for Emergent Coronary Angiography. (26942134)
2015
31
An Unusual Cause for New Right Bundle-Branch Block. (26475390)
2015
32
The Prognostic Significance of Right Bundle Branch Block: A Meta-analysis of Prospective Cohort Studies. (26436874)
2015
33
Resynchronization therapy in heart failure with right bundle branch block: new perspectives. (26253984)
2015
34
A Wide Complex Left Bundle Branch Block Tachycardia in a Patient with Complete Right Bundle Branch Block: What is the Mechanism? (25777462)
2015
35
Right ventricular septal pacing in patients with right bundle branch block. (25979817)
2015
36
Incidence and Clinical Significance of Brugada Syndrome Masked by Complete Right Bundle-Branch Block. (26447120)
2015
37
Ventricular tachycardia with right bundle branch block morphology in arrhythmogenic right ventricular cardiomyopathy. (26301673)
2015
38
Clinical and electrocardiographic characteristics of idiopathic ventricular arrhythmias with right bundle branch block and superior axis: Comparison of apical crux area and posterior septal left ventricle. (25728755)
2015
39
Erratum to: Does Surgically Induced Right Bundle Branch Block Really Effect Ventricular Function in Children After Ventricular Septal Defect Closure? (25795310)
2015
40
Effects of an Isolated Complete Right Bundle Branch Block on Mechanical Ventricular Function. (26491093)
2015
41
Another case of transient resolution of chronic complete right bundle branch block following an acute myocardial infarction. (26362883)
2015
42
Significance of an isolated new right bundle branch block in a patient with chest pain. (26055601)
2015
43
Involvement of the right ventricle in hypertrophic cardiomyopathy and occurrence of right bundle branch block. (26386927)
2015
44
High prevalence of incomplete right bundle branch block in facioscapulohumeral muscular dystrophy without cardiac symptoms. (25264980)
2014
45
Alternating left and right bundle branch block. (25343679)
2014
46
Does cardiac resynchronization therapy benefit patients with right bundle branch block: left ventricular free wall pacing: seldom right for right bundle branch block. (24951572)
2014
47
Negative association between right bundle branch block and inducibility of ventricular tachyarrhythmias in Chagas disease. (25295461)
2014
48
Does Surgically Induced Right Bundle Branch Block Really Effect Ventricular Function in Children After Ventricular Septal Defect Closure? (25293427)
2014
49
Exercise-induced right bundle branch block progressive resolution. (24591677)
2014
50
Negative association between right bundle branch block and inducibility of ventricular tachyarrhythmias in Chagas disease. Author's reply. (25422843)
2014

Variations for Right Bundle Branch Block

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Expression for genes affiliated with Right Bundle Branch Block

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Search GEO for disease gene expression data for Right Bundle Branch Block.

Pathways for genes affiliated with Right Bundle Branch Block

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Pathways related to Right Bundle Branch Block according to GeneCards Suite gene sharing:

(show all 14)
idSuper pathwaysScoreTop Affiliating Genes
19.3GPD1L, SCN3B, SCN5A
29.2CACNA1C, CACNB2
39.2CACNA1C, CACNB2
4
Show member pathways
8.9SCN1B, SCN2B, SCN3B, SCN5A
5
Show member pathways
8.9SCN1B, SCN2B, SCN3B, SCN5A
68.9SCN1B, SCN2B, SCN3B, SCN5A
78.7CACNA1C, CACNB2, KCND3
8
Show member pathways
8.5CACNA1C, CACNB2, SCN1B, SCN5A
9
Show member pathways
7.6CACNA1C, CACNB2, SCN1B, SCN2B, SCN3B, SCN5A
10
Show member pathways
7.6CACNA1C, CACNB2, SCN1B, SCN2B, SCN3B, SCN5A
11
Show member pathways
7.6CACNA1C, CACNB2, SCN1B, SCN2B, SCN3B, SCN5A
12
Show member pathways
7.3CACNA1C, CACNB2, DSG4, SCN1B, SCN2B, SCN3B
13
Show member pathways
7.1CACNA1C, CACNB2, KCND3, SCN1B, SCN2B, SCN3B
146.5CACNA1C, CACNB2, HCN4, KCND3, SCN1B, SCN2B

GO Terms for genes affiliated with Right Bundle Branch Block

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Cellular components related to Right Bundle Branch Block according to GeneCards Suite gene sharing:

(show all 11)
idNameGO IDScoreTop Affiliating Genes
1intercalated discGO:001470410.6SCN1B, SCN5A
2T-tubuleGO:003031510.4SCN1B, SCN5A
3sodium channel complexGO:003470610.3SCN1B, TRPM4
4L-type voltage-gated calcium channel complexGO:199045410.0CACNA1C, CACNB2
5voltage-gated calcium channel complexGO:00058919.8CACNA1C, CACNB2
6sarcolemmaGO:00423839.4CACNB2, KCND3, SCN5A
7voltage-gated sodium channel complexGO:00015189.4SCN1B, SCN2B, SCN3B, SCN5A
8Z discGO:00300189.2CACNA1C, SCN3B, SCN5A
9integral component of membraneGO:00160217.5CACNA1C, DSG4, HCN4, KCND3, SCN1B, SCN2B
10plasma membraneGO:00058866.5CACNA1C, CACNB2, DSG4, GPD1L, HCN4, KCND3
11membraneGO:00160206.3CACNA1C, CACNB2, DSG4, GPD1L, HCN4, KCND3

Biological processes related to Right Bundle Branch Block according to GeneCards Suite gene sharing:

(show all 35)
idNameGO IDScoreTop Affiliating Genes
1membrane depolarization during bundle of His cell action potentialGO:008604810.6SCN5A, TRPM4
2regulation of ventricular cardiac muscle cell membrane repolarizationGO:006030710.5SCN1B, SCN5A
3regulation of ventricular cardiac muscle cell action potentialGO:009891110.5CACNA1C, TRPM4
4atrial cardiac muscle cell action potentialGO:008601410.5SCN3B, SCN5A
5response to pyrethroidGO:004668410.5SCN1B, SCN2B
6membrane depolarization during action potentialGO:008601010.4SCN3B, SCN5A
7positive regulation of heart rateGO:001046010.4SCN3B, TRPM4
8membrane depolarization during SA node cell action potentialGO:008604610.3HCN4, SCN5A
9sodium ion import across plasma membraneGO:009871910.3HCN4, TRPM4
10membrane depolarization during Purkinje myocyte cell action potentialGO:008604710.2SCN1B, SCN5A, TRPM4
11regulation of ventricular cardiac muscle cell membrane depolarizationGO:006037310.1GPD1L, SCN3B, SCN5A
12membrane depolarizationGO:005189910.0SCN1B, SCN3B, SCN5A
13regulation of heart rateGO:000202710.0GPD1L, HCN4, SCN5A
14SA node cell action potentialGO:00860159.8HCN4, SCN3B, SCN5A
15positive regulation of sodium ion transportGO:00107659.7GPD1L, SCN1B, SCN3B, SCN5A
16membrane depolarization during atrial cardiac muscle cell action potentialGO:00989129.7CACNA1C, CACNB2, SCN5A
17cardiac muscle contractionGO:00600489.7SCN1B, SCN2B, SCN3B, SCN5A
18calcium ion transmembrane transportGO:00705889.7CACNA1C, CACNB2, TRPM4
19calcium ion transportGO:00068169.7CACNA1C, CACNB2, TRPM4
20regulation of atrial cardiac muscle cell membrane depolarizationGO:00603719.7SCN1B, SCN2B, SCN3B, SCN5A
21chemical synaptic transmissionGO:00072689.6CACNB2, SCN1B, SCN2B
22regulation of sodium ion transmembrane transporter activityGO:20006499.6GPD1L, SCN1B, SCN2B, SCN3B
23membrane depolarization during AV node cell action potentialGO:00860459.4CACNA1C, CACNB2, SCN5A, TRPM4
24ventricular cardiac muscle cell action potentialGO:00860059.3GPD1L, SCN3B, SCN5A
25cardiac muscle cell action potential involved in contractionGO:00860029.2CACNA1C, SCN1B, SCN2B, SCN3B, SCN5A
26regulation of postsynaptic membrane potentialGO:00600789.0HCN4, SCN1B, SCN2B, SCN3B, SCN5A
27sodium ion transmembrane transportGO:00357259.0HCN4, SCN1B, SCN2B, SCN3B, SCN5A
28sodium ion transportGO:00068149.0HCN4, SCN1B, SCN2B, SCN3B, SCN5A
29transmembrane transportGO:00550859.0CACNA1C, HCN4, KCND3, SCN5A, TRPM4
30membrane depolarization during cardiac muscle cell action potentialGO:00860128.6CACNA1C, HCN4, SCN1B, SCN2B, SCN3B, SCN5A
31cardiac conductionGO:00613377.9CACNA1C, CACNB2, KCND3, SCN1B, SCN3B, SCN5A
32regulation of ion transmembrane transportGO:00347657.2CACNA1C, CACNB2, HCN4, KCND3, SCN1B, SCN2B
33ion transportGO:00068116.9CACNA1C, CACNB2, HCN4, KCND3, SCN1B, SCN2B
34regulation of heart rate by cardiac conductionGO:00860916.9CACNA1C, CACNB2, HCN4, KCND3, SCN1B, SCN2B
35transportGO:00068106.4CACNA1C, CACNB2, HCN4, KCND3, SCN1B, SCN2B

Molecular functions related to Right Bundle Branch Block according to GeneCards Suite gene sharing:

(show all 14)
idNameGO IDScoreTop Affiliating Genes
1calmodulin bindingGO:000551610.1CACNA1C, SCN5A, TRPM4
2high voltage-gated calcium channel activityGO:00083319.9CACNA1C, CACNB2
3voltage-gated sodium channel activity involved in Purkinje myocyte action potentialGO:00860629.8SCN1B, SCN5A
4voltage-gated calcium channel activityGO:00052459.8CACNA1C, CACNB2
5voltage-gated calcium channel activity involved in AV node cell action potentialGO:00860569.8CACNA1C, CACNB2
6voltage-gated calcium channel activity involved in cardiac muscle cell action potentialGO:00860079.8CACNA1C, CACNB2
7calcium channel activityGO:00052629.6CACNA1C, CACNB2, TRPM4
8ion channel activityGO:00052169.4CACNA1C, HCN4, SCN5A, TRPM4
9ion channel bindingGO:00443259.4GPD1L, KCND3, SCN3B, SCN5A
10sodium channel regulator activityGO:00170809.1GPD1L, SCN1B, SCN2B, SCN3B, SCN5A
11voltage-gated sodium channel activity involved in cardiac muscle cell action potentialGO:00860068.8SCN1B, SCN2B, SCN3B, SCN5A
12sodium channel activityGO:00052728.5HCN4, SCN1B, SCN2B, SCN3B, SCN5A, TRPM4
13voltage-gated sodium channel activityGO:00052488.4HCN4, SCN1B, SCN2B, SCN3B, SCN5A
14voltage-gated ion channel activityGO:00052447.7CACNA1C, HCN4, KCND3, SCN1B, SCN2B, SCN3B

Sources for Right Bundle Branch Block

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet