R7
MCID: RNG023
MIFTS: 21

Ring Chromosome 7 (R7) malady

Fetal diseases category

Summaries for Ring Chromosome 7

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32MalaCards
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MalaCards: Ring Chromosome 7, also known as chromosome 7 ring, is related to holoprosencephaly and melanoma. An important gene associated with Ring Chromosome 7 is GFAP (glial fibrillary acidic protein), and among its related pathways are PIP3 activates AKT signaling and Spinal Cord Injury. The compounds bcnu and tetracycline have been mentioned in the context of this disorder.

Aliases & Classifications for Ring Chromosome 7

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Sources:
42NIH Rare Diseases, 48Orphanet, 60UMLS, 35MESH via Orphanet, 26ICD10 via Orphanet, 61UMLS via Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Fetal diseases


Aliases & Descriptions:

ring chromosome 7 42 48 60
chromosome 7 ring 42
ring 7 42
r7 42


External Ids:

MESH via Orphanet35 C537813
ICD10 via Orphanet26 Q93.2
UMLS via Orphanet61 C0795818, C2931622

Related Diseases for Ring Chromosome 7

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Ring Chromosome 7:



Diseases related to ring chromosome 7

Clinical Features for Ring Chromosome 7

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Drugs & Therapeutics for Ring Chromosome 7

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Ring Chromosome 7

Drug clinical trials:

Search ClinicalTrials for Ring Chromosome 7

Search NIH Clinical Center for Ring Chromosome 7

Search CenterWatch for Ring Chromosome 7

Genetic Tests for Ring Chromosome 7

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Anatomical Context for Ring Chromosome 7

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Animal Models for Ring Chromosome 7 or affiliated genes

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Publications for Ring Chromosome 7

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Genetic Variations for Ring Chromosome 7

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Expression for genes affiliated with Ring Chromosome 7

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Ring Chromosome 7

Search GEO for disease gene expression data for Ring Chromosome 7.

Pathways for genes affiliated with Ring Chromosome 7

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Sources:
53Reactome, 37NCBI BioSystems Database
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Pathways related to Ring Chromosome 7 according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
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9.1GFAP, EGFR
29.1GFAP, EGFR

Compounds for genes affiliated with Ring Chromosome 7

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Sources:
44Novoseek, 11DrugBank, 49PharmGKB, 28IUPHAR, 59Tocris Bioscience, 2BitterDB, 24HMDB
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Compounds related to Ring Chromosome 7 according to GeneCards/GeneDecks:

(show all 11)
idCompoundScoreTop Affiliating Genes
1bcnu449.4GFAP, EGFR
2tetracycline44 1110.4GFAP, EGFR
3agar449.3EGFR, GFAP
4paclitaxel44 49 1111.3GFAP, EGFR
5pd 98,059449.3GFAP, EGFR
6paraffin449.2EGFR, GFAP
7genistein44 28 59 2 11 2414.2GFAP, EGFR
8cisplatin44 49 59 1112.1GFAP, EGFR
9testosterone44 59 11 2412.1GFAP, EGFR
10cycloheximide449.0EGFR, GFAP
11progesterone44 59 28 11 2412.8GFAP, EGFR

GO Terms for genes affiliated with Ring Chromosome 7

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Products for genes affiliated with Ring Chromosome 7

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Ring Chromosome 7

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet