MCID: RTC003
MIFTS: 34

Root Caries malady

Gastrointestinal diseases, Oral diseases categories
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Summaries for Root Caries

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Sources:
65Wikipedia, 33MalaCards
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Wikipedia:65 Dental caries (Latin, \"rot\"), also known as tooth decay or a cavity, is an infection, bacterial in... more...

MalaCards: Root Caries, also known as dental caries of root surface, is related to periodontal disease and dental caries. An important gene associated with Root Caries is DSPP (dentin sialophosphoprotein). The compounds pmma and silicone have been mentioned in the context of this disorder. Affiliated tissues include bone.

Aliases & Classifications for Root Caries

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Sources:
8Disease Ontology, 10DISEASES, 45Novoseek, 62UMLS, 58SNOMED-CT, 27ICD9CM, 35MeSH, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Gastrointestinal diseases, Oral diseases


Aliases & Descriptions:

root caries 8 10 45 62
dental caries of root surface 8
cementum caries 8
caries 62


External Ids:

Disease Ontology8 DOID:14089
ICD9CM27 521.08
SNOMED-CT58 30512007, 234975001
MeSH35 D017213
ICD1025 K02.2

Related Diseases for Root Caries

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Root Caries via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 17)
idRelated DiseaseScoreTop Affiliating Genes
1periodontal disease30.5CD79A, DSPP
2dental caries30.1CD79A, DSPP
3periodontitis10.6
4blindness10.2
5alzheimer's disease10.1
6type 1 diabetes mellitus10.1
7cervicitis10.1
8diabetes mellitus10.1
9endocarditis10.1
10gingivitis10.0DSPP, GPI
11osteoarthritis10.0DSPP, GPI
12deficiency anemia10.0CD79A, GPI
13skin disease10.0DCD, CD79A
14tuberculosis10.0GPI, CD79A
15hypersensitivity reaction type ii disease10.0CD79A, GPI
16systemic lupus erythematosus9.9CD79A, GPI
17rheumatoid arthritis9.9GPI, DSPP, CD79A

Graphical network of diseases related to Root Caries:



Diseases related to root caries

Symptoms for Root Caries

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Drugs & Therapeutics for Root Caries

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Sources:
42NIH Clinical Center, 6ClinicalTrials, 62UMLS, 41NDF-RT
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Drug clinical trials:

Search ClinicalTrials for Root Caries

Search NIH Clinical Center for Root Caries

Genetic Tests for Root Caries

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Anatomical Context for Root Caries

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Sources:
33MalaCards
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MalaCards organs/tissues related to Root Caries:

33
Bone

Animal Models for Root Caries or affiliated genes

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Publications for Root Caries

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Sources:
52PubMed
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Articles related to Root Caries:

(show top 50)    (show all 277)
idTitleAuthorsYear
1
Comparing the efficacy of a dentifrice containing 1.5% arginine and 1450 ppm fluoride to a dentifrice containing 1450 ppm fluoride alone in the management of primary root caries. (23985437)
2013
2
Prevention of root caries: a literature review of primary and secondary preventive agents. (23600985)
2013
3
Atraumatic restorative treatment and Carisolv use for root caries in the elderly: 2-year follow-up randomized clinical trial. (23974801)
2013
4
Fluoride dentifrice containing xylitol: in vitro root caries formation. (23724551)
2013
5
A clinical investigation of the efficacy of a dentifrice containing 1.5% arginine and 1450 ppm fluoride, as sodium monofluorophosphate in a calcium base, on primary root caries. (24156137)
2013
6
A minimally invasive restorative approach for treatment of interproximal root caries lesions. (21716990)
2011
7
Root caries and risk profiles using the Cariogram in different periodontal disease severity groups. (21142897)
2011
8
A randomised trial comparing the antibacterial effects of dentine primers against bacteria in natural root caries. (22156664)
2011
9
Prevention of root caries. (21619735)
2011
10
Prevention of crown and root caries in adults. (21134238)
2011
11
Biomimetic approach for root caries prevention using a proanthocyanidin-rich agent. (21860242)
2011
12
Association between Bifidobacteriaceae and the clinical severity of root caries lesions. (19121067)
2009
13
A comparison of root caries diagnosis based on visual-tactile criteria and DIAGNOdent in vivo. (19406549)
2009
14
Longitudinal relationship between root caries and serum albumin. (17959907)
2007
15
ART for treating root caries in older people. (17589492)
2007
16
Development of an in situ root caries model. A. In vitro investigations. (15725525)
2005
17
Development of an in situ root caries model B. In situ investigations. (15725526)
2005
18
Estimating rates of new root caries in older adults. (15271973)
2004
19
Factors associated with root caries incidence in an elderly population. (14696740)
2003
20
Twenty-four month incidence of root caries among a diverse group of adults. (11641573)
2001
21
Reversal of primary root caries using dentifrices containing 5,000 and 1,100 ppm fluoride. (11125195)
2001
22
The diagnosis of root caries. (11700002)
2001
23
A cross-sectional study into the prevalence of root caries in periodontal maintenance patients. (9923507)
1999
24
Periodontal esthetics and soft-tissue root coverage for treatment of cervical root caries. (10650390)
1999
25
Dissolution of cement, root caries, fracture, and retrofit of post and cores. (9791803)
1998
26
Salivary findings, daily medication and root caries in the old elderly. (9438565)
1998
27
Distribution of coronal and root caries experience among persons aged 60+ in South Australia. (9241929)
1997
28
Root caries in vitro after low fluence argon laser and fluoride treatment. (9534364)
1997
29
Oral hygiene and root caries occurrence in Slovenian adults. (9448786)
1997
30
A computer-assisted videodensitometric method to visualize mineral distributions in in vitro and in vivo formed root caries lesions. (9085032)
1997
31
Human root caries: microbiota of a limited number of root caries lesions. (8850584)
1996
32
Root caries and root defects in urban and rural adults: the Florida Dental Care Study. (8754463)
1996
33
Effects of argon laser irradiation and acidulated phosphate fluoride on root caries. (7546465)
1995
34
An in vitro model for studying the efficacy of fluoride dentifrices in preventing root caries. (8001052)
1994
35
A comparison of primary root caries lesions classified according to colour. (8069878)
1994
36
Prevention of root caries with dentin adhesives. (8054192)
1994
37
Root caries histopathology and chemistry. (7986449)
1994
38
Restorative treatment for geriatric root caries. (7518869)
1994
39
Root caries in a sample of elderly persons. (9511633)
1993
40
A clinical comparison of a glass ionomer cement and a microfilled composite resin in restoring root caries: two-year results. (1839833)
1991
41
Effect of fluoride on root caries--an in vitro study. (1810324)
1991
42
Humoral immunity in root caries in an elderly population. 2. (2080066)
1990
43
Human root caries: histopathology of advanced lesions. (2364398)
1990
44
Root caries. (2636189)
1989
45
Incidence of coronal and root caries in an older adult population. (3422312)
1988
46
Relationship between root caries and coronal decay. (3476562)
1987
47
Root caries: a rationale for treatment. (3311841)
1987
48
Detection of root caries: sensitivity and specificity of a modified explorer. (3859442)
1985
49
Microleakage of root caries restorations. (3864708)
1985
50
Root caries. (6596149)
1984

Variations for Root Caries

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Expression for genes affiliated with Root Caries

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Sources:
2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Root Caries

Search GEO for disease gene expression data for Root Caries.

Pathways for genes affiliated with Root Caries

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Compounds for genes affiliated with Root Caries

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Sources:
45Novoseek, 11DrugBank, 24HMDB
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Compounds related to Root Caries according to GeneCards/GeneDecks:

(show all 19)
idCompoundScoreTop Affiliating Genes
1pmma459.7CD79A, DSPP
2silicone459.7CD79A, DSPP
3glutaraldehyde459.6CD79A, DSPP
4fluoride459.6CD79A, DSPP
5doxycycline45 1110.6CD79A, DSPP
6citrate459.5CD79A, DSPP
7formaldehyde45 2410.5CD79A, DSPP
8glycerol45 24 1111.4CD79A, DSPP
9starch459.4DSPP, GPI
10agar459.4DSPP, CD79A
11malate459.4GPI, DSPP
12cellulose acetate459.3CD79A, GPI
13epinephrine45 24 1111.3CD79A, DSPP
14paraffin459.3CD79A, DSPP
15carbon459.3GPI, DSPP
16ascorbic acid45 2410.2CD79A, DSPP
17vitamin d459.0CD79A, DSPP
18lactate458.8GPI, DSPP, CD79A
19glutamate458.7GPI, DSPP, CD79A

GO Terms for genes affiliated with Root Caries

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Products for genes affiliated with Root Caries

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Root Caries

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet