MCID: RTC003
MIFTS: 34

Root Caries malady

Gastrointestinal diseases, Oral diseases categories

Summaries for Root Caries

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Sources:
66Wikipedia, 34MalaCards
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Wikipedia:66 Dental caries (Latin, \"rot\"), also known as tooth decay or a cavity, is an infection, bacterial in... more...

MalaCards: Root Caries, also known as dental caries of root surface, is related to periodontal disease and dental caries. An important gene associated with Root Caries is DSPP (dentin sialophosphoprotein). The compounds pmma and silicone have been mentioned in the context of this disorder. Affiliated tissues include bone.

Aliases & Classifications for Root Caries

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Sources:
9Disease Ontology, 11DISEASES, 46Novoseek, 63UMLS, 59SNOMED-CT, 28ICD9CM, 36MeSH, 26ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Gastrointestinal diseases, Oral diseases


Aliases & Descriptions:

root caries 9 11 46 63
dental caries of root surface 9
cementum caries 9
caries 63


External Ids:

Disease Ontology9 DOID:14089
ICD9CM28 521.08
SNOMED-CT59 30512007, 234975001
MeSH36 D017213
ICD1026 K02.2

Related Diseases for Root Caries

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Sources:
18GeneCards, 19GeneDecks
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Diseases related to Root Caries via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 17)
idRelated DiseaseScoreTop Affiliating Genes
1periodontal disease30.5CD79A, DSPP
2dental caries30.1CD79A, DSPP
3periodontitis10.6
4blindness10.2
5alzheimer's disease10.1
6type 1 diabetes mellitus10.1
7cervicitis10.1
8diabetes mellitus10.1
9endocarditis10.1
10gingivitis10.0DSPP, GPI
11osteoarthritis10.0DSPP, GPI
12deficiency anemia10.0CD79A, GPI
13skin disease10.0DCD, CD79A
14tuberculosis10.0GPI, CD79A
15hypersensitivity reaction type ii disease10.0CD79A, GPI
16systemic lupus erythematosus9.9CD79A, GPI
17rheumatoid arthritis9.9GPI, DSPP, CD79A

Graphical network of diseases related to Root Caries:



Diseases related to root caries

Symptoms for Root Caries

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Drugs & Therapeutics for Root Caries

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 63UMLS, 42NDF-RT
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Approved drugs:

Search CenterWatch for Root Caries

Drug clinical trials:

Search ClinicalTrials for Root Caries

Search NIH Clinical Center for Root Caries

Search CenterWatch for Root Caries

Genetic Tests for Root Caries

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Anatomical Context for Root Caries

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Sources:
34MalaCards
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MalaCards organs/tissues related to Root Caries:

34
Bone

Animal Models for Root Caries or affiliated genes

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Publications for Root Caries

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Sources:
53PubMed
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Articles related to Root Caries:

(show top 50)    (show all 277)
idTitleAuthorsYear
1
Comparing the efficacy of a dentifrice containing 1.5% arginine and 1450 ppm fluoride to a dentifrice containing 1450 ppm fluoride alone in the management of primary root caries. (23985437)
2013
2
Prevention of root caries: a literature review of primary and secondary preventive agents. (23600985)
2013
3
Atraumatic restorative treatment and Carisolv use for root caries in the elderly: 2-year follow-up randomized clinical trial. (23974801)
2013
4
Fluoride dentifrice containing xylitol: in vitro root caries formation. (23724551)
2013
5
A clinical investigation of the efficacy of a dentifrice containing 1.5% arginine and 1450 ppm fluoride, as sodium monofluorophosphate in a calcium base, on primary root caries. (24156137)
2013
6
A minimally invasive restorative approach for treatment of interproximal root caries lesions. (21716990)
2011
7
Root caries and risk profiles using the Cariogram in different periodontal disease severity groups. (21142897)
2011
8
A randomised trial comparing the antibacterial effects of dentine primers against bacteria in natural root caries. (22156664)
2011
9
Prevention of root caries. (21619735)
2011
10
Prevention of crown and root caries in adults. (21134238)
2011
11
Biomimetic approach for root caries prevention using a proanthocyanidin-rich agent. (21860242)
2011
12
Association between Bifidobacteriaceae and the clinical severity of root caries lesions. (19121067)
2009
13
A comparison of root caries diagnosis based on visual-tactile criteria and DIAGNOdent in vivo. (19406549)
2009
14
Longitudinal relationship between root caries and serum albumin. (17959907)
2007
15
ART for treating root caries in older people. (17589492)
2007
16
Development of an in situ root caries model. A. In vitro investigations. (15725525)
2005
17
Development of an in situ root caries model B. In situ investigations. (15725526)
2005
18
Estimating rates of new root caries in older adults. (15271973)
2004
19
Factors associated with root caries incidence in an elderly population. (14696740)
2003
20
Twenty-four month incidence of root caries among a diverse group of adults. (11641573)
2001
21
Reversal of primary root caries using dentifrices containing 5,000 and 1,100 ppm fluoride. (11125195)
2001
22
The diagnosis of root caries. (11700002)
2001
23
A cross-sectional study into the prevalence of root caries in periodontal maintenance patients. (9923507)
1999
24
Periodontal esthetics and soft-tissue root coverage for treatment of cervical root caries. (10650390)
1999
25
Dissolution of cement, root caries, fracture, and retrofit of post and cores. (9791803)
1998
26
Salivary findings, daily medication and root caries in the old elderly. (9438565)
1998
27
Distribution of coronal and root caries experience among persons aged 60+ in South Australia. (9241929)
1997
28
Root caries in vitro after low fluence argon laser and fluoride treatment. (9534364)
1997
29
Oral hygiene and root caries occurrence in Slovenian adults. (9448786)
1997
30
A computer-assisted videodensitometric method to visualize mineral distributions in in vitro and in vivo formed root caries lesions. (9085032)
1997
31
Human root caries: microbiota of a limited number of root caries lesions. (8850584)
1996
32
Root caries and root defects in urban and rural adults: the Florida Dental Care Study. (8754463)
1996
33
Effects of argon laser irradiation and acidulated phosphate fluoride on root caries. (7546465)
1995
34
An in vitro model for studying the efficacy of fluoride dentifrices in preventing root caries. (8001052)
1994
35
A comparison of primary root caries lesions classified according to colour. (8069878)
1994
36
Prevention of root caries with dentin adhesives. (8054192)
1994
37
Root caries histopathology and chemistry. (7986449)
1994
38
Restorative treatment for geriatric root caries. (7518869)
1994
39
Root caries in a sample of elderly persons. (9511633)
1993
40
A clinical comparison of a glass ionomer cement and a microfilled composite resin in restoring root caries: two-year results. (1839833)
1991
41
Effect of fluoride on root caries--an in vitro study. (1810324)
1991
42
Humoral immunity in root caries in an elderly population. 2. (2080066)
1990
43
Human root caries: histopathology of advanced lesions. (2364398)
1990
44
Root caries. (2636189)
1989
45
Incidence of coronal and root caries in an older adult population. (3422312)
1988
46
Relationship between root caries and coronal decay. (3476562)
1987
47
Root caries: a rationale for treatment. (3311841)
1987
48
Detection of root caries: sensitivity and specificity of a modified explorer. (3859442)
1985
49
Microleakage of root caries restorations. (3864708)
1985
50
Root caries. (6596149)
1984

Variations for Root Caries

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Expression for genes affiliated with Root Caries

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Root Caries

Search GEO for disease gene expression data for Root Caries.

Pathways for genes affiliated with Root Caries

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Compounds for genes affiliated with Root Caries

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Sources:
46Novoseek, 12DrugBank, 25HMDB
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Compounds related to Root Caries according to GeneCards/GeneDecks:

(show all 19)
idCompoundScoreTop Affiliating Genes
1pmma469.7CD79A, DSPP
2silicone469.7CD79A, DSPP
3glutaraldehyde469.6CD79A, DSPP
4fluoride469.6CD79A, DSPP
5doxycycline46 1210.6CD79A, DSPP
6citrate469.5CD79A, DSPP
7formaldehyde46 2510.5CD79A, DSPP
8glycerol46 25 1211.4CD79A, DSPP
9starch469.4DSPP, GPI
10agar469.4DSPP, CD79A
11malate469.4GPI, DSPP
12cellulose acetate469.3CD79A, GPI
13epinephrine46 25 1211.3CD79A, DSPP
14paraffin469.3CD79A, DSPP
15carbon469.3GPI, DSPP
16ascorbic acid46 2510.2CD79A, DSPP
17vitamin d469.0CD79A, DSPP
18lactate468.8GPI, DSPP, CD79A
19glutamate468.7GPI, DSPP, CD79A

GO Terms for genes affiliated with Root Caries

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Products for genes affiliated with Root Caries

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Root Caries

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet