Aliases & Classifications for Root Resorption

MalaCards integrated aliases for Root Resorption:

Name: Root Resorption 12 42 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:14550
MeSH 42 D012391
UMLS 69 C0035851

Summaries for Root Resorption

MalaCards based summary : Root Resorption is related to singleton-merten syndrome 1 and prothrombin thrombophilia. An important gene associated with Root Resorption is TNFSF11 (TNF Superfamily Member 11), and among its related pathways/superpathways are Cytokine Signaling in Immune system and Development Endothelin-1/EDNRA signaling. The drugs Mitogens and Chlorhexidine have been mentioned in the context of this disorder. Affiliated tissues include bone and thyroid, and related phenotypes are hematopoietic system and homeostasis/metabolism

Related Diseases for Root Resorption

Diseases related to Root Resorption via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 106)
id Related Disease Score Top Affiliating Genes
1 singleton-merten syndrome 1 10.9
2 prothrombin thrombophilia 10.7 IL1B TNFRSF11B
3 cortical blindness 10.7 TNFRSF11B TNFSF11
4 larynx leiomyosarcoma 10.7 TNFRSF11A TNFSF11
5 peripheral scars of retina 10.7 TNFRSF11B TNFSF11
6 gastric cancer risk after h. pylori infection 10.6 IL1B IL1RN
7 walker dyson syndrome 10.6 IL1B IL1RN
8 milk allergy 10.6 IL1B IL1RN
9 hypochondrogenesis 10.6 CALCA TNFRSF11B
10 indolent myeloma 10.5 IL1B IL1RN
11 atrial heart septal defect 10.5 CALCA TNFRSF11A
12 polyembryoma 10.4 TNFRSF11A TNFRSF11B TNFSF11
13 paget disease of bone 2, early-onset 10.4 TNFRSF11A TNFRSF11B TNFSF11
14 hennekam van der horst syndrome 10.4 TNFRSF11A TNFRSF11B TNFSF11
15 bacterial gastritis 10.4 IL1B TNFRSF11B TNFSF11
16 spinocerebellar ataxia 4 10.4 TNFRSF11A TNFRSF11B TNFSF11
17 keloids 10.4 IL1B IL1RN TNFSF11
18 hypophosphatasia, adult 10.4 CALCA SPP1
19 senile reticular retinal degeneration 10.4 IL1B IL1RN
20 toxic optic neuropathy 10.4 IL1A IL1B
21 epulis 10.4 DSPP IL1B
22 psoriasis susceptibility 1 10.4 IL1RN TNFRSF11B TNFSF11
23 carotenemia 10.4 IL1RN TNFRSF11A TNFRSF11B
24 cinca syndrome 10.4 IL1B IL1RN
25 spinocerebellar ataxia, autosomal recessive 18 10.4 DSPP SPP1
26 osteochondrosis 10.3 IL1B TNFRSF11B TNFSF11
27 subglottis neoplasm 10.3 DSPP IL1B
28 scrotal carcinoma 10.3 IL1A IL1B
29 cervicitis 10.3
30 bullous retinoschisis 10.3 DSPP IL1B
31 gliosarcoma 10.3 IL1A IL1B
32 eye disease 10.3 DSPP SPP1
33 atrial fibrillation, familial, 8 10.3 CALCA TNFRSF11A TNFSF11
34 periodontitis 10.3
35 lung sarcoma 10.3 IL1A IL1B
36 impotence 10.3 IL1A TNFSF11
37 van buchem disease, type 2 10.3 CTSK TNFRSF11B TNFSF11
38 stargardt macular degeneration absent or hypoplastic corpus callosum mental retardation and dysmorphic features 10.3 IL1A IL1B
39 corneal staphyloma 10.2 CTSK DSPP
40 pancreas adenocarcinoma 10.2 CTSK TNFRSF11A TNFSF11
41 liver disease 10.2 IL1A IL1B
42 depressed scar 10.2 DSPP SPP1
43 intrahepatic cholestasis 10.2 P2RX7 TNFRSF11A TNFSF11
44 lipoid nephrosis 10.2 IL1A TNFSF11
45 acquired thrombocytopenia 10.1 DSPP IL1B
46 synovium cancer 10.1 IL1B IL1RN TNFRSF11B TNFSF11
47 neuropathy 10.1 IL1A TNFRSF11B TNFSF11
48 mental retardation dysmorphism hypogonadism diabetes 10.1 IL1A IL1B IL1RN
49 polyradiculoneuropathy 10.1 CALCA CTSK SPP1
50 placenta accreta 10.1 IL1A IL1B IL1RN

Graphical network of the top 20 diseases related to Root Resorption:



Diseases related to Root Resorption

Symptoms & Phenotypes for Root Resorption

MGI Mouse Phenotypes related to Root Resorption:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.1 P2RX7 RUNX2 SPP1 TNFRSF11A TNFRSF11B TNFSF11
2 homeostasis/metabolism MP:0005376 10.02 CTSK IL1A IL1B IL1RN P2RX7 RUNX2
3 immune system MP:0005387 10.02 CTSK IL1A IL1B IL1RN P2RX7 RUNX2
4 cardiovascular system MP:0005385 10 SPP1 TNFRSF11B IL1A IL1B IL1RN P2RX7
5 craniofacial MP:0005382 9.91 CTSK RUNX2 SPP1 TNFRSF11A TNFRSF11B TNFSF11
6 integument MP:0010771 9.86 IL1A IL1B IL1RN P2RX7 RUNX2 SPP1
7 limbs/digits/tail MP:0005371 9.63 TNFRSF11B TNFSF11 CTSK P2RX7 RUNX2 TNFRSF11A
8 neoplasm MP:0002006 9.35 IL1A IL1B SPP1 TNFRSF11A TNFSF11
9 skeleton MP:0005390 9.28 CTSK IL1B IL1RN P2RX7 RUNX2 SPP1

Drugs & Therapeutics for Root Resorption

Drugs for Root Resorption (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 28)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1 Mitogens Phase 1
2
Chlorhexidine Approved, Vet_approved 55-56-1 9552079 2713
3
Epinephrine Approved, Vet_approved 51-43-4 5816
4
Lidocaine Approved, Vet_approved 137-58-6 3676
5 Racepinephrine Approved
6
Miconazole Approved, Investigational, Vet_approved 22916-47-8 4189
7
Salicylic acid Approved, Vet_approved 69-72-7 338
8
Alginic acid Approved, Experimental 9005-32-7
9
Copper Approved 7440-50-8 27099
10
Menthol Approved 2216-51-5 16666
11 Orange Approved, Nutraceutical
12 Anesthetics
13 Anesthetics, Local
14 Calcium, Dietary
15 Chlorhexidine gluconate
16 Epinephryl borate
17 Antifungal Agents
18 Anti-Infective Agents
19 Central Nervous System Depressants
20 Dermatologic Agents
21 Keratolytic Agents
22 Anti-Bacterial Agents
23 Antibiotics, Antitubercular
24 Analgesics
25 Anti-Inflammatory Agents
26
Nickel 7440-02-0 934
27 Pharmaceutical Solutions
28 Bone Density Conservation Agents

Interventional clinical trials:

(show all 37)

id Name Status NCT ID Phase Drugs
1 A Comparision of Collagen Matrix and Connective Tissue Graft With Modified Coronally Advanced Tunnel for Root Coverage Recruiting NCT02876562 Phase 4
2 Repair of Orthodontically-induced Tooth Root Resorption by Ultrasound Unknown status NCT00423956 Phase 1, Phase 2
3 Histological Change of The Dentinal-Pulp Complex and Root Resorption Completed NCT01642693 Phase 1, Phase 2
4 Periodontal Ligament Stress Level and Tooth Movement Completed NCT00099814 Phase 1
5 Use of PRP in Treatment of Mandibular Traumatic Bone Cyst Completed NCT01944410 Phase 1
6 Treatment of Crowding Without Extraction Using Self Ligating Brackets Recruiting NCT02996292 Phase 1
7 Volumetric Analysis of Root Resorption With Mini-Screw Implant Anchorage-assisted Retraction of Maxillary Incisors Unknown status NCT02221206
8 Assessment of Piezoelectric Periodontal Surgery Effects on Orthodontic Treatment: a Prospective Pilot Study Unknown status NCT02359760
9 Periodontally Accelerated Orthodontics - A Novel Technique For a Shortened Orthodontic Treatment With a Stable Result. A Clinical and Computerized Tomography Analysis Unknown status NCT01628575
10 Computer-Aided Design/Computer-Aided Manufacturing (CAD/CAM) - Based Planning and Creation of Orthodontic Appliances Unknown status NCT00871026
11 Comparison of Oral Hygiene & Root Resorption During Orthodontic Treatment Completed NCT02745626
12 An Evaluation of Root Length Measurements Using Intraoral Scan and Panoramic Radiographs Completed NCT02822040
13 Effect of Pulpotomy Using TheraCal Versus MTA on Survival Rate of Cariously-Exposed Vital Permanent Molars Completed NCT03119779 MTA-Anglus;TheraCal
14 Micro-osteoperforations and Tooth Movement Completed NCT02473471
15 Premolar Autotransplantation in Juvenile Dentition: Quantitative Assessment of Vertical Bone and Soft Tissue Growth Completed NCT02740907
16 Checking Occlusion During Stainless Steel Crown Placement Completed NCT02437565
17 The Effect of Ultrasound on Orthodontic Tooth Movement Completed NCT01828164
18 Antimicrobial Pastes and Clinical Cases of Apexogenesis Completed NCT03112291
19 Intermittent Vibrational Force and Orthodontic Tooth Movement Completed NCT02314975
20 Efficiency of Piezocision-assisted Orthodontic Treatment in Adult Patients Completed NCT02590835
21 Efficacy and the Safety Study of RD94 in Patients With Endodontic Care Completed NCT01737229
22 Titanium Prepared Platelet Rich Fibrin for Multiple Gingival Recessions Completed NCT03121872
23 Labial Alveolar Bone Thickness and Apical Root Resorption Changes Associated With Self-ligating Versus Conventional Brackets Recruiting NCT02816489
24 Orthodontic Archwire Comparison Trial Recruiting NCT02983084
25 Biomarkers of Orthodontic Tooth Movement With Fixed Appliances and Vibration Appliance Therapy Recruiting NCT02119455
26 The Effect of OrthoPulse Photobiomodulation on the Rate of Tooth Movement During Alignment With Fixed Appliances Recruiting NCT03202355
27 The Effect of OrthoPulse™ Photobiomodulation on Tooth Movement and Treatment Time When Used With Invisalign Treatment Recruiting NCT02954133
28 The Effect of Different Force Magnitudes on Maxillary Posterior Segment Intrusion Recruiting NCT02901678
29 The Use of Corticotomy for Upper Incisors Retraction Recruiting NCT03149016
30 Closed Window vs. Open Window Technique in Management of Palatally Impacted Canines Recruiting NCT02582645
31 Socket Shield Technique Versus Conventional Immediate Implant Placement in Thin Buccofacial Bone Recruiting NCT03264053
32 Crossbow Versus Forsus Springs in Mild to Moderate Class II Malocclusion Cases Active, not recruiting NCT01530516
33 Application of Different Biomaterials in the Preservation of Vital Pulp in Carious Deciduous Teeth Active, not recruiting NCT03220360
34 The Impact of Surgical Technique on PDC Active, not recruiting NCT02186548
35 Evaluation of the Effects of Osteoperforation and Piezocorticision on Canine Retraction Not yet recruiting NCT03308851
36 Orthodontic Archwire Effectiveness Trial Not yet recruiting NCT02659813
37 Randomized, Blinded, Controlled Clinical Trial of Surgically Facilitated Orthodontic Treatment Withdrawn NCT01866345

Search NIH Clinical Center for Root Resorption

Cochrane evidence based reviews: root resorption

Genetic Tests for Root Resorption

Anatomical Context for Root Resorption

MalaCards organs/tissues related to Root Resorption:

39
Bone, Thyroid

Publications for Root Resorption

Articles related to Root Resorption:

(show top 50) (show all 638)
id Title Authors Year
1
A preliminary investigation of short-termA cytokineA expression in gingival crevicular fluid secondary to high-level orthodontic forces and the associated root resorption: case series analytical study. ( 28762151 )
2017
2
Evaluation of maxillary central incisors on the noncleft and cleft sides in patients with unilateral cleft lip and palate-Part 2: Relationship between root resorption, horizontal tooth movement, and quantity of grafted autogenous bone. ( 28906140 )
2017
3
Comparative study of root resorption of maxillary incisors in patients treated with lingual and buccal orthodontics. ( 28737425 )
2017
4
Piezocision and root resorption: AA biased conclusion? ( 28554442 )
2017
5
Types of External Root Resorption of Replanted Teeth: Analysis of the Clinical Aspects and of Interleukin-4 Gene Polymorphisms Involvement. ( 28818443 )
2017
6
Analysis of the association of clinical factors and IL4 gene polymorphisms with root resorption in avulsed teeth after 1A year of replantation. ( 28617966 )
2017
7
Assessment of Root Resorption and Root Shape by Periapical and Panoramic Radiographs: A Comparative Study. ( 28621278 )
2017
8
Management of Ankylotic Root Resorption Following Dental Trauma: A Short Review and Proposal of a Treatment Protocol. ( 28761940 )
2017
9
Severe root resorption of the upper central incisors as a consequence of playing the flute. ( 28602035 )
2017
10
Meloxicam medication reduces orthodontically induced dental root resorption and tooth movement velocity: a combined in vivo and in vitro study of dental-periodontal cells and tissue. ( 28044198 )
2017
11
Three consecutive days of application of LED therapy is necessary to inhibit experimentally induced root resorption in rats: a microtomographic study. ( 27796672 )
2017
12
Multidisciplinary approach for replacement a8"root resorption following severe intrusive luxation: a8"A case report of decoronation. ( 28555199 )
2017
13
The Role of Varicella Zoster Virus in the Development of Periapical Pathoses and Root Resorption: A Systematic Review. ( 28662875 )
2017
14
Impact of cone-beam computed tomography scan mode on the diagnostic yield of chemically simulated external root resorption. ( 28554453 )
2017
15
Decoronation: An Alternative Treatment for Replacement Root Resorption. ( 28573052 )
2017
16
Markers in blood and saliva for prediction of orthodontically induced inflammatory root resorption: a retrospective case controlled-study. ( 28782095 )
2017
17
Effects of calcitonin on orthodontic tooth movement and associated root resorption in rats. ( 28814141 )
2017
18
Management of Invasive Cervical Root Resorption in a Mandibular Canine Using Biodentine as a Restorative Material: A Case Report. ( 28808471 )
2017
19
Management of root resorption with mineral trioxide aggregate complicated by a luxation injury: report of a case with six-year follow-up. ( 28065972 )
2017
20
Comparison of 4 and 6A weeks of rest period for repair of root resorption. ( 28670661 )
2017
21
Orthodontic-surgical retreatment of facial asymmetry with occlusal cant and severe root resorption: A 3-year follow-up. ( 28760289 )
2017
22
Cellular and Molecular Pathways Leading to External Root Resorption. ( 27811065 )
2017
23
Diagnostic accuracy of phosphor plate systems and conventional radiography in the detection of simulated internal root resorption. ( 28754080 )
2017
24
Effects of short-term in-vivo studies on orthodontic root resorption paradigms. ( 28651756 )
2017
25
Effect of piezocision on root resorption associated with orthodontic force: A microcomputed tomography study. ( 28024782 )
2017
26
A radiographic study of external apical root resorption in patients treated with single-phase fixed orthodontic therapy. ( 28050063 )
2016
27
Comparison of anterior and posterior mini-implant-assisted maxillary incisor intrusion: Root resorption and treatment efficiency. ( 26741306 )
2016
28
Apical External Root Resorption and Repair in Orthodontic Tooth Movement: Biological Events. ( 27119080 )
2016
29
Root resorption during orthodontic treatment with self-ligating or conventional brackets: a systematic review and meta-analysis. ( 27871255 )
2016
30
Evaluation of cone beam computed tomography and periapical radiography in the diagnosis of root resorption. ( 26780040 )
2016
31
Conservative management of external root resorption after tooth reimplantation: a 3-year follow-up. ( 27367632 )
2016
32
Conservative Management of Class 4 Invasive Cervical Root Resorption Using Calcium-enriched Mixture Cement. ( 27316319 )
2016
33
Comparative evaluation of the accuracy of two electronic apex locators in determining the working length in teeth with simulated apical root resorption: An in vitro study. ( 27656055 )
2016
34
A Randomized Trial Using 3Mixtatin Compared to MTA in Primary Molars with Inflammatory Root Resorption: A Novel Endodontic Biomaterial. ( 26950808 )
2016
35
Quantitive evaluation of dentin sialoprotein (DSP) using microbeads - a potential early marker of root resorption. ( 28042441 )
2016
36
Clinical Management of Two Root Resorption Cases in Endodontic Practice. ( 27648314 )
2016
37
Impacted maxillary canines and root resorption of adjacent teeth: A retrospective observational study. ( 27694788 )
2016
38
Canine-lateral incisor transposition: Controlling root resorption with a bone-anchored T-loop retraction. ( 27894525 )
2016
39
Effect of bisphosphonates on root resorption after tooth replantation - a systematic review. ( 27960049 )
2016
40
Effects of Low-Intensity Pulsed Ultrasound on Orthodontic Tooth Movement and Orthodontically Induced Inflammatory Root Resorption in Ovariectomized Osteoporotic Rats. ( 26742893 )
2016
41
External root resorption with the self-ligating Damon system-a retrospective study. ( 27365168 )
2016
42
Diagnostic Accuracy of Cone-Beam Computed Tomography and Periapical Radiography in Internal Root Resorption. ( 26843878 )
2016
43
A posteriori registration and subtraction of periapical radiographs for the evaluation of external apical root resorption after orthodontic treatment. ( 27051635 )
2016
44
Scanning electron microscopy reveals severe external root resorption in the large periapical lesion. ( 26957368 )
2016
45
Osteoprotegerin-Knockout Mice Developed Early Onset Root Resorption. ( 27663616 )
2016
46
IRAK1 variant is protective for orthodontic-induced external apical root resorption. ( 27250598 )
2016
47
Asymptomatic, nonexpansile radiopacity of the jaw associated with external root resorption: a diagnostic dilemma. ( 26742164 )
2016
48
TGF-I^ and Physiological Root Resorption of Deciduous Teeth. ( 28035998 )
2016
49
Orthodontic Treatment of Maxillary Incisors with Severe Root Resorption Caused by Bilateral Canine Impaction in a Class II Division 1 Patient. ( 26950820 )
2016
50
Effect of Voxel Size on Detection of External Root Resorption Defects Using Cone Beam Computed Tomography. ( 27853499 )
2016

Variations for Root Resorption

Expression for Root Resorption

Search GEO for disease gene expression data for Root Resorption.

Pathways for Root Resorption

Pathways related to Root Resorption according to GeneCards Suite gene sharing:

(show all 23)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.14 IL1A IL1B IL1RN TNFRSF11A TNFRSF11B TNFSF11
2
Show member pathways
12.55 IL1B TNFRSF11A TNFRSF11B TNFSF11
3 12.33 IL1B IL1RN TNFRSF11A TNFSF11
4
Show member pathways
12.3 IL1A IL1B TNFRSF11A TNFRSF11B TNFSF11
5
Show member pathways
12.26 IL1B IL1RN TNFRSF11A TNFSF11
6
Show member pathways
12.19 CTSK TNFRSF11A TNFRSF11B TNFSF11
7
Show member pathways
12.08 IL1A IL1B IL1RN
8 11.96 IL1A IL1B IL1RN
9 11.74 CTSK IL1A IL1B TNFRSF11A TNFRSF11B TNFSF11
10 11.68 IL1B TNFRSF11A TNFSF11
11 11.61 CTSK IL1A IL1B TNFRSF11A TNFSF11
12
Show member pathways
11.58 TNFRSF11A TNFRSF11B TNFSF11
13 11.41 CALCA IL1B SPP1
14 11.27 IL1A IL1B IL1RN
15 11.16 IL1A IL1B
16 11.15 IL1A IL1B
17 11.09 RUNX2 SPP1 TNFSF11
18 11.07 IL1A IL1B
19 10.99 IL1A IL1B TNFSF11
20 10.88 CALCA IL1A IL1B RUNX2 SPP1 TNFRSF11A
21 10.7 TNFRSF11B TNFSF11
22 10.56 CTSK SPP1 TNFRSF11A TNFRSF11B TNFSF11
23 10.3 IL1A IL1B

GO Terms for Root Resorption

Cellular components related to Root Resorption according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.56 CALCA CTSK IL1A IL1B IL1RN SPP1
2 vesicle GO:0031982 9.33 IL1B IL1RN SPP1
3 extracellular region GO:0005576 9.28 CALCA CTSK DSPP IL1A IL1B IL1RN

Biological processes related to Root Resorption according to GeneCards Suite gene sharing:

(show all 36)
id Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.91 IL1A IL1B IL1RN TNFRSF11B TNFSF11
2 positive regulation of gene expression GO:0010628 9.89 IL1A IL1B P2RX7 RUNX2
3 extracellular matrix organization GO:0030198 9.84 DSPP SPP1 TNFRSF11B
4 skeletal system development GO:0001501 9.81 DSPP RUNX2 TNFRSF11B
5 cytokine-mediated signaling pathway GO:0019221 9.8 IL1A IL1B TNFSF11
6 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.8 IL1B TNFRSF11A TNFSF11
7 response to lipopolysaccharide GO:0032496 9.8 IL1B P2RX7 TNFRSF11A TNFRSF11B
8 tumor necrosis factor-mediated signaling pathway GO:0033209 9.79 TNFRSF11A TNFRSF11B TNFSF11
9 positive regulation of sequence-specific DNA binding transcription factor activity GO:0051091 9.75 IL1B TNFRSF11A TNFSF11
10 apoptotic signaling pathway GO:0097190 9.71 P2RX7 TNFRSF11A TNFRSF11B
11 biomineral tissue development GO:0031214 9.67 DSPP SPP1
12 extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 9.67 IL1A IL1B
13 positive regulation of cytokine secretion GO:0050715 9.66 IL1A P2RX7
14 positive regulation of interleukin-8 production GO:0032757 9.65 CALCA IL1B
15 positive regulation of vascular endothelial growth factor production GO:0010575 9.65 IL1A IL1B
16 positive regulation of mitotic nuclear division GO:0045840 9.65 IL1A IL1B
17 osteoclast differentiation GO:0030316 9.64 TNFRSF11A TNFSF11
18 bone resorption GO:0045453 9.64 CTSK TNFSF11
19 positive regulation of interleukin-6 production GO:0032755 9.63 IL1A IL1B P2RX7
20 response to ATP GO:0033198 9.62 IL1B P2RX7
21 mammary gland alveolus development GO:0060749 9.61 TNFRSF11A TNFSF11
22 embryo implantation GO:0007566 9.61 CALCA IL1B SPP1
23 positive regulation of ossification GO:0045778 9.6 CALCA P2RX7
24 positive regulation of bone resorption GO:0045780 9.58 SPP1 TNFSF11
25 monocyte chemotaxis GO:0002548 9.58 CALCA TNFRSF11A TNFSF11
26 positive regulation of interleukin-2 biosynthetic process GO:0045086 9.57 IL1A IL1B
27 positive regulation of monocyte chemotactic protein-1 production GO:0071639 9.56 IL1A IL1B
28 ossification GO:0001503 9.56 DSPP RUNX2 TNFRSF11A TNFSF11
29 ectopic germ cell programmed cell death GO:0035234 9.55 IL1A IL1B
30 positive regulation of prostaglandin secretion GO:0032308 9.52 IL1B P2RX7
31 TNFSF11-mediated signaling pathway GO:0071847 9.48 TNFRSF11A TNFSF11
32 positive regulation of fever generation by positive regulation of prostaglandin secretion GO:0071812 9.37 TNFRSF11A TNFSF11
33 negative regulation of bone resorption GO:0045779 9.33 CALCA P2RX7 TNFRSF11B
34 positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling GO:0071848 9.32 TNFRSF11A TNFSF11
35 inflammatory response GO:0006954 9.23 CALCA IL1A IL1B IL1RN P2RX7 SPP1
36 fever generation GO:0001660 8.96 IL1A IL1B

Molecular functions related to Root Resorption according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 tumor necrosis factor-activated receptor activity GO:0005031 9.16 TNFRSF11A TNFRSF11B
2 interleukin-1 receptor binding GO:0005149 9.13 IL1A IL1B IL1RN
3 cytokine activity GO:0005125 9.1 IL1A IL1B IL1RN SPP1 TNFRSF11B TNFSF11

Sources for Root Resorption

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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