MCID: RTR008
MIFTS: 36

Root Resorption malady

Oral diseases category
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Summaries for Root Resorption

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Wikipedia:65 In dentistry, root resorption is the breakdown or destruction, and subsequent loss, of the root... more...

MalaCards based summary: Root Resorption is related to cervicitis and periodontitis. An important gene associated with Root Resorption is AMELX (amelogenin, X-linked), and among its related pathways is Degradation of the extracellular matrix. The compounds hydrogen and hydroxyapatite have been mentioned in the context of this disorder. Affiliated tissues include bone and thyroid, and related mouse phenotypes are limbs/digits/tail and craniofacial.

Aliases & Classifications for Root Resorption

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Root Resorption, Aliases & Descriptions:

Name: Root Resorption 8 10 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Oral diseases


External Ids:

Disease Ontology8 DOID:14550
MeSH34 D012391

Related Diseases for Root Resorption

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Diseases related to Root Resorption via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 26)
idRelated DiseaseScoreTop Affiliating Genes
1cervicitis10.7
2periodontitis10.7
3gingivitis10.5
4atopic dermatitis10.3
5dermatitis10.3
6periodontal disease10.3
7amelogenesis imperfecta10.1
8gingival recession10.1
9hereditary hemorrhagic telangiectasia10.1
10marfan syndrome10.1
11ankylosis10.1
12fibroma10.1
13hypercementosis10.1
14fibrous dysplasia10.1
15osteoblastoma10.1
16neuronitis10.1
17ehlers-danlos syndrome10.1
18scleroderma10.1
19thyroiditis10.1
20ehlers-danlos syndrome, type viii10.1
21x-linked hypophosphatemia10.1DMP1, CLCN5
22hypophosphatemia10.0CLCN5, DMP1
23rickets10.0DMP1, CLCN5
24arthritis9.8CTSK, GDF5
25short stature9.8CTSK, GDF5
26osteoarthritis9.7CTSK, GDF5

Graphical network of the top 20 diseases related to Root Resorption:



Diseases related to root resorption

Symptoms for Root Resorption

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Drugs & Therapeutics for Root Resorption

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Drug clinical trials:

Search ClinicalTrials for Root Resorption

Search NIH Clinical Center for Root Resorption

Genetic Tests for Root Resorption

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Anatomical Context for Root Resorption

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MalaCards organs/tissues related to Root Resorption:

32
Bone, Thyroid

Animal Models for Root Resorption or affiliated genes

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MGI Mouse Phenotypes related to Root Resorption:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053718.5CTSK, DMP1, GDF5
2MP:00053828.1DMP1, AMELX, CLCN5, CTSK
3MP:00053907.4CTSK, CLCN5, AMELX, DMP1, GDF5

Publications for Root Resorption

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Articles related to Root Resorption:

(show top 50)    (show all 515)
idTitleAuthorsYear
1
The association between traumatic dental injuries and atypical external root resorption in maxillary primary incisors. (25283588)
2014
2
A comparison of apical root resorption after orthodontic treatment with surgical exposure and traction of maxillary impacted canines versus that without impactions. (24406478)
2014
3
Accuracy of conventional and digital radiography in detecting external root resorption. (25386202)
2014
4
Pixel value analysis for detection of simulated early external root resorption. (25229785)
2014
5
Comparison between electrochemical ELISA and spectrophotometric ELISA for the detection of dentine sialophosphoprotein for root resorption. (24373653)
2014
6
Ankylosed maxillary incisor with severe root resorption treated with a single-tooth dento-osseous osteotomy, vertical alveolar distraction osteogenesis, and mini-implant anchorage. (25172260)
2014
7
The effect of ovalbumin on orthodontic induced root resorption. (24348621)
2013
8
Treatment of maxillary central incisor with external root resorption using mineral trioxide aggregate: 18 months follow-up. (23843419)
2013
9
The effect of celecoxib on orthodontic tooth movement and root resorption in rat. (24396349)
2013
10
Polymorphisms of genes encoding P2X7R, IL-1B, OPG and RANK in orthodontic-induced apical root resorption. (24118270)
2013
11
Radiographic comparison of the extent of orthodontically induced external apical root resorption in vital and root-filled teeth: a systematic review. (23321851)
2013
12
Effect of platelet-derived growth factor-BB on root resorption after reimplantation of partially denuded tooth in dog. (22051114)
2012
13
Postorthodontic external root resorption is associated with IL1 receptor antagonist gene variations. (22035161)
2012
14
Icariin enhances the healing of rapid palatal expansion induced root resorption in rats. (22818561)
2012
15
Aggressive external root resorption of the entire dentition accompanied by osteolysis: a case report. (22930767)
2012
16
Effects of intrusion combined with anterior retraction on apical root resorption. (21389075)
2012
17
Localized idiopathic apical root resorption: a report of five cases with emphasis on differential diagnosis. (22479784)
2012
18
Primary teeth show less protecting factors against root resorption. (21481035)
2011
19
Physical properties of root cementum: Part 16. Comparisons of root resorption and resorption craters after the application of light and heavy continuous and controlled orthodontic forces for 4, 8, and 12 weeks. (21392672)
2011
20
Tooth movement and root resorption; the effect of ovariectomy on orthodontic force application in rats. (21361777)
2011
21
Root resorption caused by a maxillary sinus mucocele: a case report. (21444223)
2011
22
Root resorption in the furcation area: a differential diagnostic consideration. (20629542)
2010
23
Repair of root resorption 4 and 8 weeks after application of continuous light and heavy forces on premolars for 4 weeks: a histology study. (21130331)
2010
24
Case report: A cautionary tale of impacted palatal premolars and molar root resorption. (20099607)
2009
25
Interleukin-1 polymorphisms in relation to external apical root resorption (EARR). (19194673)
2009
26
Detection of root resorption using dentin and bone markers. (19627525)
2009
27
Treatment of aggressive external root resorption with calcium hydroxide medicaments: a case report. (19519861)
2009
28
Ectopic maxillary canines and root resorption of adjacent incisors. Does computed tomography (CT) influence decision-making by orthodontists? (19172919)
2008
29
Three-dimensional mechanical environment of orthodontic tooth movement and root resorption. (18538239)
2008
30
Radiographic evaluation of the prevalence of root resorption in a Middle Eastern population. (18560639)
2008
31
The effect of intracanal anti-inflammatory medicaments on external root resorption of replanted dog teeth after extended extra-oral dry time. (18173671)
2008
32
Tooth movement characteristics in relation to root resorption in young and adult rats. (18028051)
2007
33
The flaws in tooth root resorption assessment algorithms: the role of source position. (17699700)
2007
34
Lateral incisor root resorption and active orthodontic treatment in the early mixed dentition. (18163854)
2007
35
Root resorption after orthodontic treatment. (17203580)
2006
36
Inflammatory external root resorption following surgical treatment for intra-bony defects: a report of two cases involving Emdogain and a review of the literature. (16677335)
2006
37
Expression of mRNA for osteoprotegerin and receptor activator of nuclear factor kappa beta ligand (RANKL) during root resorption induced by the application of heavy orthodontic forces on rat molars. (16214633)
2005
38
Can the severity of root resorption be accurately judged by means of radiographs? A case report with histology. (16027634)
2005
39
Pulp-dentine complex changes and root resorption during intrusive orthodontic tooth movement in patients prescribed nabumetone. (15614010)
2005
40
Severe external root resorption arrested by conventional endodontic treatment. (15938342)
2005
41
Root resorption in dental trauma: 45 cases followed for 5 years. (14708650)
2003
42
Prevalence of different periapical lesions associated with human teeth and their correlation with the presence and extension of apical external root resorption. (12196225)
2002
43
Combined therapy of mineral trioxide aggregate and guided tissue regeneration in the treatment of external root resorption and an associated osseous defect. (12546103)
2002
44
In vitro measurement accuracy of an electronic apex locator in teeth with simulated apical root resorption. (12067130)
2002
45
Deciduous canine and permanent lateral incisor differential root resorption. (11606957)
2001
46
Root resorption. (11270379)
2001
47
Apical root resorption of upper first molars as related to anchorage system. (11140541)
2000
48
Evaluation of apical root resorption following extraction therapy in subjects with Class I and Class II malocclusions. (10565089)
1999
49
Radiographic assessment of simulated external root resorption cavities in maxillary incisors. (9863423)
1998
50
Ultrastructural and cytochemical study of the odontoclasts in physiologic root resorption of human deciduous teeth. (1328451)
1992

Variations for Root Resorption

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Expression for genes affiliated with Root Resorption

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Expression patterns in normal tissues for genes affiliated with Root Resorption

Search GEO for disease gene expression data for Root Resorption.

Pathways for genes affiliated with Root Resorption

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Pathways related to Root Resorption according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
8.5CTSK, DMP1, GDF5

Compounds for genes affiliated with Root Resorption

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Sources:
44Novoseek, 24HMDB
See all sources

Compounds related to Root Resorption according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1hydrogen44 2410.3CTSK, CLCN5
2hydroxyapatite449.2CTSK, DMP1
3chloride449.0CTSK, CLCN5

GO Terms for genes affiliated with Root Resorption

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Cellular components related to Root Resorption according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1proteinaceous extracellular matrixGO:0055789.2AMELX, DMP1
2extracellular regionGO:0055768.5CTSK, DMP1, GDF5

Biological processes related to Root Resorption according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1biomineral tissue developmentGO:0312149.4AMELX, DMP1
2chondrocyte differentiationGO:0020629.2AMELX, GDF5
3extracellular matrix organizationGO:0301988.2CTSK, DMP1, GDF5

Molecular functions related to Root Resorption according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1growth factor activityGO:0080839.2AMELX, GDF5

Products for genes affiliated with Root Resorption

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  • Antibodies
  • Proteins
  • Lysates

Sources for Root Resorption

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet