MCID: RSC001
MIFTS: 43

Rosacea malady

Skin diseases category

Summaries for Rosacea

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MedlinePlus:32 Rosacea is a long-term disease that affects your skin and sometimes your eyes. it causes redness and pimples. rosacea is most common in women and people with fair skin. it most often affects middle-aged and older adults. in most cases, rosacea only affects the face. symptoms can include frequent redness of the face, or flushing small, red lines under the skin acne a swollen nose thick skin, usually on the forehead, chin, and cheeks red, dry, itchy eyes and sometimes vision problems no one knows what causes rosacea. you may be more likely to have it if you blush a lot or if rosacea runs in your family. rosacea is not dangerous. there is no cure, but treatments can help. they include medicines and sometimes surgery. nih: national institute of arthritis and musculoskeletal and skin diseases

MalaCards based summary: Rosacea, also known as acne, erythematosa, is related to acne and granulomatous rosacea. An important gene associated with Rosacea is CAMP (cathelicidin antimicrobial peptide). The drugs loteprednol etabonate and loteprednol and the compounds xanthine and p002 have been mentioned in the context of this disorder. Affiliated tissues include skin, eye and b cells.

Wikipedia:63 Rosacea /ro??ze??i?/ is a chronic skin condition characterized by facial redness, small and superficial... more...

Aliases & Classifications for Rosacea

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Rosacea, Aliases & Descriptions:

Name: Rosacea 9 11 32 60
Acne, Erythematosa 9
Acne Rosacea 9
 
Acne Roscea 9
Rosacea Nos 9


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Skin diseases


External Ids:

Disease Ontology9 DOID:8881
ICD9CM27 695.3
MeSH33 D012393
ICD1025 L71, L71.9

Related Diseases for Rosacea

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Graphical network of the top 20 diseases related to Rosacea:



Diseases related to rosacea

Symptoms for Rosacea

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Drugs & Therapeutics for Rosacea

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Genetic Tests for Rosacea

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Anatomical Context for Rosacea

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MalaCards organs/tissues related to Rosacea:

31
Skin, Eye, B cells, Small intestine, Testes, Salivary gland, Myeloid, T cells, Endothelial, Neutrophil

Animal Models for Rosacea or affiliated genes

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Publications for Rosacea

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Articles related to Rosacea:

(show top 50)    (show all 566)
idTitleAuthorsYear
1
Rosacea: Part II. Topical and systemic therapies in the treatment of rosacea. (25890456)
2015
2
Successful treatment of recalcitrant granulomatous rosacea with oral thalidomide and topical pimecrolimus. (25753523)
2015
3
Multi-drugs resistant acne rosacea in a child affected by Ataxia-Telangiectasia: successful treatment with Isotretinoin. (25881033)
2015
4
Assessment of the Genetic Basis of Rosacea by Genome-Wide Association Study. (25695682)
2015
5
Antinuclear antibodies in rosacea patients. (24278039)
2013
6
Rosacea - S1 guideline. (23647643)
2013
7
Potential role of microorganisms in the pathogenesis of rosacea. (24011460)
2013
8
Vitamin D status in patients with rosacea. (23713748)
2013
9
Management of facial erythema of rosacea: what is the role of topical I+-adrenergic receptor agonist therapy? (24229637)
2013
10
Migraine, triptans, and the risk of developing rosacea: a population-based study within the United Kingdom. (23643255)
2013
11
Steroid dermatitis resembling rosacea: a clinical evaluation of 75 patients. (23691345)
2013
12
Molecular biologic assessment of cutaneous specimens of ocular rosacea. (22617640)
2012
13
Potential role of Demodex mites and bacteria in the induction of rosacea. (22933353)
2012
14
Randomized, double-blind trial of 220 mg zinc sulfate twice daily in the treatment of rosacea. (22435439)
2012
15
Is it acne or is it rosacea? An important distinction. (22988645)
2012
16
A randomized, double-blind, placebo-controlled, pilot study to assess the efficacy and safety of clindamycin 1.2% and tretinoin 0.025% combination gel for the treatment of acne rosacea over 12 weeks. (22395584)
2012
17
Facial redness and rosacea... (22183094)
2011
18
Rosacea as a disease of cathelicidins and skin innate immunity. (22076322)
2011
19
Epidermal proteases in the pathogenesis of rosacea. (22076323)
2011
20
Management of Papulopustular Rosacea and Perioral Dermatitis with Emphasis on Iatrogenic Causation or Exacerbation of Inflammatory Facial Dermatoses: Use of Doxycycline-modified Release 40mg Capsule Once Daily in Combination with Properly Selected Skin Care as an Effective Therapeutic Approach. (21909455)
2011
21
Long-term efficacy and safety of topical PRK 124 (0.125%) lotion (Pyratine-XR) in the treatment of mild-to-moderate rosacea. (20645526)
2010
22
Clinical and laboratory study of rosacea in northern Greece. (19744179)
2010
23
Updates on the pathophysiology and management of acne rosacea. (19820288)
2009
24
The metabolism and pharmacokinetics of isotretinoin in patients with acne and rosacea are not influenced by ethanol. (19563582)
2009
25
Concentration of selected cytokines in serum of patients with acne rosacea]. (19140384)
2008
26
Successful treatment of erythematotelangiectatic rosacea with pulsed light and radiofrequency. (21103309)
2008
27
Rosacea/acne rosacea: efficacy of combination therapy of azithromycin and topical 0.1% tacrolimus ointment. (18435734)
2008
28
Healthcare utilization and costs of patients with rosacea in an insured population. (18246697)
2008
29
Severe exacerbation of rosacea induced by cinnamon supplements. (18561592)
2008
30
A role for vascular pathogenic mechanisms in rosacea: implications for patient care. (18792539)
2008
31
Combined effect of anti-inflammatory dose doxycycline (40-mg doxycycline, usp monohydrate controlled-release capsules) and metronidazole topical gel 1% in the treatment of rosacea. (17668530)
2007
32
Wegener's granulomatosis mimicking facial granulomatous rosacea: a separate subset? (17989900)
2007
33
Increased serine protease activity and cathelicidin promotes skin inflammation in rosacea. (17676051)
2007
34
Lymphangiogenesis and angiogenesis in non-phymatous rosacea. (17880579)
2007
35
Rosacea. (18183803)
2007
36
Wegener's granulomatosis presenting with granulomatous facial erythematous papules and plaques mimicking granulomatous rosacea. (16792787)
2006
37
Metronidazole in the treatment of rosacea: do formulation, dosing, and concentration matter? (16673797)
2006
38
Autosomal dominant familial chronic mucocutaneous candidiasis associated with acne rosacea. (16284681)
2005
39
Dendritic keratopathy in ocular rosacea. (15968176)
2005
40
Assessment of skin barrier function in rosacea patients with a novel 1% metronidazole gel. (16167413)
2005
41
Could matrix metalloproteinase-9 be a link between Demodex folliculorum and rosacea? (16164733)
2005
42
Group IIA phospholipase A(2) concentration of tears in patients with ocular rosacea. (16029275)
2005
43
Rosacea. An overview of diagnosis and management. (15615217)
2004
44
BsmI polymorphism of the vitamin D receptor gene in patients with the fulminant course of rosacea conglobata (rosacea fulminans). (15187348)
2004
45
Helicobacter pylori and rosacea. (15562747)
2003
46
Laser treatment of rosacea. (17147538)
2002
47
Resolution of granulomatous rosacea after eradication of Helicobacter pylori with clarithromycin, metronidazole and pantoprazole. (11692067)
2001
48
Granulomatous rosacea in a child infected with the human immunodeficiency virus. (1479080)
1992
49
Demodicidosis mimicking granulomatous rosacea and transient acantholytic dermatosis (Grover's disease). (2958377)
1987
50
ROSACEA-LIKE DEMODICIDOSIS. (18732637)
1963

Variations for Rosacea

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Expression for genes affiliated with Rosacea

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Search GEO for disease gene expression data for Rosacea.

Pathways for genes affiliated with Rosacea

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Compounds for genes affiliated with Rosacea

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Compounds related to Rosacea according to GeneCards Suite gene sharing:

(show all 30)
idCompoundScoreTop Affiliating Genes
1xanthine43 2410.8ADSL, MMP8
2p002439.7GSTT1, MMP8
3urea43 24 1211.7ADSL, MMP8
48-bromo-cyclic amp439.6CGA, CAMP
5(+-)-pgf2-alpha439.6CAMP, CGA
6percoll439.6CGA, CAMP
7clodronate43 49 1211.6CGA, MMP8
8prostaglandin f2alpha439.6CAMP, CGA
9dbc-amp439.6CGA, CAMP
10ifosfamide43 1210.5CGA, GSTT1
11carboplatin43 49 1211.4CGA, GSTT1
12cytochalasin d43 5910.4CAMP, CGA
13ibmx43 59 2811.4CGA, CAMP
14clonidine43 49 28 1212.4CGA, NISCH
15oligonucleotide439.4GSTT1, CAMP, MMP8
16prostaglandin439.2CGA, CAMP
17cyclophosphamide43 49 1211.2CGA, GSTT1
18pge2439.1CGA, CAMP, MMP8
19folate439.1GSTT1, CGA
20progesterone43 28 59 24 1213.1CGA, CAMP, MMP8
21adenylate439.1CGA, CAMP, ADSL
22vegf439.1CGA, CAMP, MMP8
23steroid439.0CAMP, GSTT1, CGA
24creatinine439.0ADSL, GSTT1, CGA
25prostacyclin438.9CGA, CAMP
26glutamate438.9CGA, CAMP, ADSL
27glucose438.9NISCH, CAMP, MMP8
28lipid438.8MMP8, CAMP, GSTT1, NISCH
29estrogen438.8CGA, GSTT1, CAMP
30arginine438.8GSTT1, NISCH, CGA

GO Terms for genes affiliated with Rosacea

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Cellular components related to Rosacea according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cytosolGO:00058298.4NISCH, GSTT1, CAMP, ADSL

Products for genes affiliated with Rosacea

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Rosacea

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet