MCID: SCR024
MIFTS: 27

Sacrococcygeal Teratoma malady

Category: Rare diseases

Aliases & Classifications for Sacrococcygeal Teratoma

About this section

Aliases & Descriptions for Sacrococcygeal Teratoma:

Name: Sacrococcygeal Teratoma 35 48 68

Classifications:



Summaries for Sacrococcygeal Teratoma

About this section
NIH Rare Diseases:48 A sacrococcygeal teratoma is a tumor that grows at the base of the spine in a developing fetus.  it occurs in one in 40,000 newborns and girls are four times more likely to be affected than boys.  though it is usually benign, there is a possibility that the teratoma could become malignant.  as such, the recommended treatment of a teratoma is complete removal of the tumor by surgery, performed soon after the birth.  if not all of the tumor is removed during the initial surgery, the teratoma may grow back (recur) and additional surgeries may be needed.  studies have found that sacrococcygeal teratomas recur in up to 22% of cases. last updated: 10/18/2013

MalaCards based summary: Sacrococcygeal Teratoma is related to teratoma and parameningeal embryonal rhabdomyosarcoma. An important gene associated with Sacrococcygeal Teratoma is CGA (Glycoprotein Hormones, Alpha Polypeptide), and among its related pathways is Glucocorticoid receptor regulatory network. Affiliated tissues include heart, pituitary and adrenal gland.

Wikipedia:71 Sacrococcygeal teratoma (SCT) is a type of tumor known as a teratoma that develops at the base of the... more...

Related Diseases for Sacrococcygeal Teratoma

About this section

Diseases related to Sacrococcygeal Teratoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 64)
idRelated DiseaseScoreTop Affiliating Genes
1teratoma11.0
2parameningeal embryonal rhabdomyosarcoma10.0CGA, CGB7
3renal pelvis transitional cell carcinoma10.0AFP, CGA
4hydrops fetalis10.0
5true unicornuate uterus10.0AFP, CGA
6pontine hemorrhage10.0AFP, CGA
7ovarian mucinous cystadenocarcinoma10.0CGA, CGB7
8novak syndrome10.0AFP, CGB7
9chromosome 11q duplication9.9AFP, CGA
10malignant teratocarcinosarcoma9.9AFP, CGA
11lymph node disease9.9AFP, CGA
12ophthalmoplegia, progressive, with scrotal tongue and mental deficiency9.9AFP, CGA
13mucositis9.9AFP, MNX1
14breast myoepithelial neoplasm9.9AFP, CGA
153-methylglutaconic aciduria9.9AFP, MNX1
16neuroblastoma9.9
17cardiac arrest9.9
18cornelia de lange syndrome9.9
19urethritis9.9
20endodermal sinus tumor9.9
21vaginitis9.9
22adenocarcinoma9.9
23fibrosarcoma9.9
24ring chromosome 219.9
25schinzel giedion syndrome9.9
26toxascariasis9.9AFP, MNX1
27fibrous dysplasia9.8AFP, MNX1
28diabetes mellitus, insulin-resistant, with acanthosis nigricans9.8AFP, CGA
29hmg-coa synthase-2 deficiency9.8AFP, MNX1
30trypanosomiasis, human east-african9.8AFP, CGA, CGB7
31hereditary renal cell carcinoma9.8AFP, CGA, CGB7
32chordoma9.7
33currarino syndrome9.7
34klippel-trenaunay-weber syndrome9.7
35congestive heart failure9.7
36hemangioma9.7
37hemolytic anemia9.7
38hydrocephalus9.7
39scoliosis9.7
40thrombosis9.7
41meningocele9.7
42gastroschisis9.7
43hydronephrosis9.7
44cauda equina syndrome9.7
45neurogenic bladder9.7
46down syndrome9.7
47squamous cell carcinoma9.7
48hypogonadism9.7
49pseudomyxoma peritonei9.7
50retinitis9.7

Graphical network of the top 20 diseases related to Sacrococcygeal Teratoma:



Diseases related to sacrococcygeal teratoma

Symptoms & Phenotypes for Sacrococcygeal Teratoma

About this section

Drugs & Therapeutics for Sacrococcygeal Teratoma

About this section

Interventional clinical trials:

idNameStatusNCT IDPhase
1Treatment Outcome and Quality of Life in Patients With Pediatric Extra-Cranial Germ Cell Tumors Previously Treated on Clinical Trial CCLG-GC-1979-01 or CCLG-GC-1989-01Unknown statusNCT00436774
2Characterization of At-risk Population for Pre-sacral Tumor in CURRARINO SyndromeCompletedNCT00780117

Search NIH Clinical Center for Sacrococcygeal Teratoma

Genetic Tests for Sacrococcygeal Teratoma

About this section

Anatomical Context for Sacrococcygeal Teratoma

About this section

MalaCards organs/tissues related to Sacrococcygeal Teratoma:

36
Heart, Pituitary, Adrenal gland, Placenta, Lung, Liver, Bone

LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Sacrococcygeal Teratoma:
id TissueAnatomical CompartmentCell Relevance
1 Primitive StreakPrimitive Streak  Affected by disease

Publications for Sacrococcygeal Teratoma

About this section

Articles related to Sacrococcygeal Teratoma:

(show top 50)    (show all 430)
idTitleAuthorsYear
1
Analysis of Recurrent Sacrococcygeal Teratoma in Children: Clinical Features, Relapse Risks, and Anorectal Functional Sequelae. (28042962)
2017
2
Fetus in Fetu in Lieu of a Sacrococcygeal Teratoma: A Case Illuminating the Utility of Serial Prenatal Sonographic Examinations in Diagnosis. (28026891)
2017
3
Evaluation of chemotherapeutic sequelae and quality of life in survivors of malignant sacrococcygeal teratoma. (26667016)
2016
4
Anaesthestic management of sacrococcygeal teratoma in infants. (27212735)
2016
5
Acardiac twin pregnancies part II: Fetal risk of chorangioma and sacrococcygeal teratoma predicted by pump/acardiac umbilical vein diameters. (27273226)
2016
6
VACTERL Association with Sacrococcygeal Teratoma. (27567656)
2016
7
Sacrococcygeal Teratoma associated with Trisomy 13. (27398323)
2016
8
Pediatric intraocular immature teratoma associated with sacrococcygeal teratoma: case report and review of the literature. (27385488)
2016
9
Hemorrhage is the most common cause of neonatal mortality in patients with sacrococcygeal teratoma. (27502009)
2016
10
Type IV Sacrococcygeal Teratoma Displacing the Urinary Bladder: Unique Magnetic Resonance Imaging. (27413571)
2016
11
Prenatal diagnosis of tethered spinal cord associated with sacrococcygeal teratoma. (26892808)
2016
12
Use of intraoperative lateral pelvic X-ray to localize and ensure coccyx removal during sacrococcygeal teratoma resection. (27858188)
2016
13
Benign sacrococcygeal teratoma incidentally found on routine scoliosis radiographs in a 12-year-old female: a case report. (27069263)
2016
14
Sacrococcygeal Teratoma: Mistreated With Repeated Aspirations. (27398327)
2016
15
Patient-Reported Defecation and Micturition Problems Among Adults Treated for Sacrococcygeal Teratoma During Childhood-The Need for New Surveillance Strategies. (26739142)
2016
16
Hydrocephalus secondary to chemotherapy in a case of prenatally diagnosed giant immature grade 3 sacrococcygeal teratoma: A case report and literature review. (27787388)
2016
17
Sacrococcygeal teratoma with complete adrenal gland. (26881658)
2015
18
Sacrococcygeal teratoma with ectopic immature renal tissue. (25673616)
2015
19
Sexual function after treatment for sacrococcygeal teratoma during childhood. (26460155)
2015
20
Sacrococcygeal Teratoma with Yolk Sac Component in a Neonate. (26290815)
2015
21
Sacrococcygeal teratoma: case report. (26079985)
2015
22
Benign and Infected Sacrococcygeal Teratoma in a 13-year-old Girl. (26064810)
2015
23
Adult Sacrococcygeal Teratoma: The third leg: A rare case report in a 25 year old man. (26275739)
2015
24
Cornelia de Lange syndrome due to mosaic NIPBL mutation: antenatal presentation with sacrococcygeal teratoma. (26276849)
2015
25
A Huge Fetal Sacrococcygeal Teratoma with a Vascular Disruption Sequence. (26029981)
2015
26
The first description of metyrapone use in severe Cushing Syndrome due to ectopic ACTH secretion in an infant with immature sacrococcygeal teratoma. Case Report. (26859587)
2015
27
Quality of life in adulthood after resection of a sacrococcygeal teratoma in childhood: a Dutch multicentre study. (25634960)
2015
28
Laparoscopic Approach to Type IV Sacrococcygeal Teratoma in an Adult. (25972646)
2015
29
Predictors of poor prognosis in prenatally diagnosed sacrococcygeal teratoma: A multiinstitutional review. (25783370)
2015
30
Sacrococcygeal teratoma: A population-based study of incidence and prenatal prognostic factors. (26454470)
2015
31
Sacrococcygeal teratoma with intradural extension: case report. (25612665)
2015
32
Sonographic features of congenital infantile fibrosarcoma that appeared as a sacrococcygeal teratoma during pregnancy. (26013636)
2015
33
Sacrococcygeal teratoma in a female newborn with clinical features of trisomy 13: a case report from Central Africa. (26715863)
2015
34
Malignant transformation in sacrococcygeal teratoma and in presacral teratoma associated with Currarino syndrome: a comparative study. (25746708)
2015
35
Multi-stage resection and repair for the treatment of adult giant sacrococcygeal teratoma: A case report and literature review. (26171044)
2015
36
A review of pregnancies complicated by congenital sacrococcygeal teratoma in the West Midlands region over an 18-year period: population-based, cohort study. (26114890)
2015
37
Surgical outcomes in adults with benign and malignant sacrococcygeal teratoma: a single-institution experience of 26 cases. (24901686)
2014
38
The Case of Sacrococcygeal Teratoma in an IVF Pregnancy: Is There any Association between Congenital Tumors and Assisted Reproduction Techniques? (24918084)
2014
39
Analysis of recurrence risks for sacrococcygeal teratoma in children. (25487496)
2014
40
Evaluation of pregnancy and delivery in 13 women who underwent resection of a sacrococcygeal teratoma during early childhood. (25495179)
2014
41
Diagnosis of sacrococcygeal teratoma using two and three-dimensional ultrasonography: two cases reported and a literature review. (25110773)
2014
42
Re: minimally invasive therapy for fetal sacrococcygeal teratoma: case series and systematic review of the literature. T. Van Mieghem, A. Al-Ibrahim, J. Deprest, L. Lewi, J. C. Langer, D. Baud, K. O'Brien, R. Beecroft, R. Chaturvedi, E. Jaeggi, J. Fish and G. Ryan. Ultrasound Obstet Gynecol 2014; 43: 611-619. (24888741)
2014
43
Management of preterm giant sacrococcygeal teratoma (GSCT) with an excellent outcome. (25480837)
2014
44
The Clinical Relevance of Fetal MRI in the Diagnosis of Type IV Cystic Sacrococcygeal Teratoma-A Review. (25183379)
2014
45
Increased incidence of retroperitoneal teratomas and decreased incidence of sacrococcygeal teratomas in infants with Down syndrome. (23904199)
2014
46
Turnbull-Cutait abdominoperineal pull-through: a safe approach for recurrent sacrococcygeal teratoma complicated by rectovaginal fistula. (24599763)
2014
47
The long-term outcome of patients diagnosed with sacrococcygeal teratoma in childhood. A study of a national cohort. (25005525)
2014
48
Sacrococcygeal teratoma with nephroblastic elements: a case report and review of literature. (25550874)
2014
49
Sacrococcygeal teratoma growth rate predicts adverse outcomes. (24888848)
2014
50
Minimally invasive therapy for fetal sacrococcygeal teratoma: case series and systematic review of the literature. (24488859)
2014

Variations for Sacrococcygeal Teratoma

About this section

Expression for genes affiliated with Sacrococcygeal Teratoma

About this section
Search GEO for disease gene expression data for Sacrococcygeal Teratoma.

Pathways for genes affiliated with Sacrococcygeal Teratoma

About this section

Pathways related to Sacrococcygeal Teratoma according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.1AFP, CGA

GO Terms for genes affiliated with Sacrococcygeal Teratoma

About this section

Biological processes related to Sacrococcygeal Teratoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cell-cell signalingGO:00072679.4CGA, CGB7

Molecular functions related to Sacrococcygeal Teratoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1hormone activityGO:00051799.4CGA, CGB7

Sources for Sacrococcygeal Teratoma

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet