MCID: SCR024
MIFTS: 28

Sacrococcygeal Teratoma malady

Rare diseases category

Aliases & Classifications for Sacrococcygeal Teratoma

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Aliases & Descriptions for Sacrococcygeal Teratoma:

Name: Sacrococcygeal Teratoma 32 45 65


Classifications:



Summaries for Sacrococcygeal Teratoma

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NIH Rare Diseases:45 A sacrococcygeal teratoma is a tumor that grows at the base of the spine in a developing fetus.  it occurs in one in 40,000 newborns and girls are four times more likely to be affected than boys.  though it is usually benign, there is a possibility that the teratoma could become malignant.  as such, the recommended treatment of a teratoma is complete removal of the tumor by surgery, performed soon after the birth.  if not all of the tumor is removed during the initial surgery, the teratoma may grow back (recur) and additional surgeries may be needed.  studies have found that sacrococcygeal teratomas recur in up to 22% of cases. last updated: 10/18/2013

MalaCards based summary: Sacrococcygeal Teratoma is related to teratoma and hydrops fetalis. An important gene associated with Sacrococcygeal Teratoma is MNX1 (Motor Neuron And Pancreas Homeobox 1), and among its related pathways are Peptide hormone metabolism and Glucocorticoid receptor regulatory network. Affiliated tissues include heart, pituitary and placenta, and related mouse phenotype endocrine/exocrine gland.

Wikipedia:68 Sacrococcygeal teratoma (SCT) is a type of tumor known as a teratoma that develops at the base of the... more...

Related Diseases for Sacrococcygeal Teratoma

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Graphical network of the top 20 diseases related to Sacrococcygeal Teratoma:



Diseases related to sacrococcygeal teratoma

Symptoms for Sacrococcygeal Teratoma

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Drugs & Therapeutics for Sacrococcygeal Teratoma

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Interventional clinical trials:

idNameStatusNCT IDPhase
1Characterization of At-risk Population for Pre-sacral Tumor in CURRARINO SyndromeCompletedNCT00780117
2Treatment Outcome and Quality of Life in Patients With Pediatric Extra-Cranial Germ Cell Tumors Previously Treated on Clinical Trial CCLG-GC-1979-01 or CCLG-GC-1989-01RecruitingNCT00436774

Search NIH Clinical Center for Sacrococcygeal Teratoma

Genetic Tests for Sacrococcygeal Teratoma

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Anatomical Context for Sacrococcygeal Teratoma

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MalaCards organs/tissues related to Sacrococcygeal Teratoma:

33
Heart, Pituitary, Placenta, Lung, Liver, Bone, Eye

LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Sacrococcygeal Teratoma:
id TissueAnatomical CompartmentCell Relevance
1 Primitive StreakPrimitive Streak  Affected by disease

Animal Models for Sacrococcygeal Teratoma or affiliated genes

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MGI Mouse Phenotypes related to Sacrococcygeal Teratoma:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053798.5AFP, CGA, MNX1

Publications for Sacrococcygeal Teratoma

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Articles related to Sacrococcygeal Teratoma:

(show top 50)    (show all 409)
idTitleAuthorsYear
1
Adult Sacrococcygeal Teratoma: The third leg: A rare case report in a 25 year old man. (26275739)
2015
2
Sacrococcygeal teratoma with ectopic immature renal tissue. (25673616)
2015
3
Management of preterm giant sacrococcygeal teratoma (GSCT) with an excellent outcome. (25480837)
2014
4
Minimally invasive therapy for fetal sacrococcygeal teratoma: case series and systematic review of the literature. (24488859)
2014
5
The long-term psychosocial outcomes following excision of sacrococcygeal teratoma: a national study. (24277662)
2013
6
Two cases of prenatally diagnosed sacrococcygeal teratoma type I with different clinical features. (23751044)
2013
7
Intra-abdominal (Type IV) sacrococcygeal teratoma presenting with buttock hemangioma. (24057924)
2013
8
Tumor metrics and morphology predict poor prognosis in prenatally diagnosed sacrococcygeal teratoma: a 25-year experience at a single institution. (23845611)
2013
9
Large sacrococcygeal teratoma hindering vaginal delivery attempted at home. (22866184)
2012
10
Echocardiographic risk stratification of fetuses with sacrococcygeal teratoma and twin-reversed arterial perfusion. (22086180)
2011
11
Partial trisomy 3q in a child with sacrococcygeal teratoma and Cornelia de Lange syndrome phenotype. (21848013)
2011
12
Foetal sacrococcygeal teratoma: extremes in clinical presentation. (21731981)
2011
13
Long-term outcomes of surgery for malignant sacrococcygeal teratoma: 20-year experience of a regional UK centre. (19184053)
2009
14
Sacrococcygeal teratoma in an adult female Nigerian. (19253526)
2008
15
Low-grade mucinous epithelial neoplasm (intestinal type) arising in a mature sacrococcygeal teratoma with late recurrence as pseudomyxoma peritonei. (18289636)
2008
16
Prenatal diagnosis of type I sacrococcygeal teratoma and its management. (18581776)
2008
17
Corticotrophin-dependent Cushing syndrome due to Sacrococcygeal Teratoma detected by [18F]fluorodeoxyglucose positron emission tomography. (18772458)
2008
18
Mature sacrococcygeal teratoma: case report. (19357734)
2008
19
Mirror syndrome associated with sacrococcygeal teratoma: a case report. (17465292)
2007
20
Neurogenic bladder dysfunction after sacrococcygeal teratoma resection. (16406929)
2006
21
Factors associated with recurrence and metastasis in sacrococcygeal teratoma. (17058315)
2006
22
Spontaneous rupture of fetal sacrococcygeal teratoma. (16912491)
2006
23
Management of sacrococcygeal teratoma of the fetus. (15321048)
2004
24
Abnormal umbilical cord Dopplers may predict impending demise in fetuses with sacrococcygeal teratoma. A report of 2 cases. (14564114)
2003
25
Prenatal diagnosis of sacrococcygeal teratoma: a review of cases between 1993 and 2000. (12013082)
2002
26
Sacrococcygeal teratoma. (12415361)
2002
27
Sacrococcygeal teratoma: 25 year experience. (11336088)
2001
28
Successful intrauterine shunting of a sacrococcygeal teratoma (SCT) causing fetal bladder obstruction. (11746122)
2001
29
Successful fetal sacrococcygeal teratoma resection in a hydropic fetus. (11051157)
2000
30
DNA ploidy analysis and cell proliferation in congenital sacrococcygeal teratomas. (10951360)
2000
31
Sacrococcygeal teratoma associated with a normal alpha-fetoprotein concentration. (9286870)
1997
32
Sacrococcygeal teratoma in Zaria, Nigeria: report of 47 cases. (8687206)
1995
33
Neonatal sacrococcygeal teratoma: prolonged survival after malignant relapse. (7703049)
1995
34
Lower urinary tract dysfunction in children with benign sacrococcygeal teratoma. (8254808)
1994
35
The association of sacrococcygeal teratoma with high anorectal and genital malformations. (8117204)
1994
36
Anorectal function in adults operated for a benign sacrococcygeal teratoma. (8308684)
1993
37
Urological aspects of sacrococcygeal teratoma in children. (8345616)
1993
38
Sacrococcygeal teratoma and venous shunting through a tumor: biological evidence. (1734786)
1992
39
Sacrococcygeal teratoma in Sweden: a 10-year national retrospective study. (1282543)
1992
40
Neonatal sacrococcygeal teratoma: multiimaging modality assessment. (2193140)
1990
41
Prenatal sonographic diagnosis of congenital sacrococcygeal teratoma and management. (2681670)
1989
42
Sacrococcygeal teratoma: computed tomography evaluation. (3581859)
1987
43
Vaginal delivery impeded by a large fetal sacrococcygeal teratoma: anesthetic considerations. (3688507)
1987
44
Giant sacrococcygeal teratoma in an African child. (3829022)
1986
45
Sacrococcygeal teratoma: American Academy of Pediatrics Surgical Section Survey-1973. (4843993)
1974
46
Sacrococcygeal teratoma. (14405262)
1959
47
Sacrococcygeal teratoma. (13533715)
1958
48
Sacrococcygeal teratoma including case report. (13040721)
1953
49
A case of congenital sacrococcygeal teratoma. (14886605)
1951
50
Sacrococcygeal teratoma with urinary retention. (15403717)
1950

Variations for Sacrococcygeal Teratoma

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Expression for genes affiliated with Sacrococcygeal Teratoma

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Search GEO for disease gene expression data for Sacrococcygeal Teratoma.

Pathways for genes affiliated with Sacrococcygeal Teratoma

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Pathways related to Sacrococcygeal Teratoma according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.3CGA, CGB7
29.0AFP, CGA

GO Terms for genes affiliated with Sacrococcygeal Teratoma

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Biological processes related to Sacrococcygeal Teratoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1pancreas developmentGO:00310169.6AFP, MNX1
2peptide hormone processingGO:00164869.4CGA, CGB7
3cell-cell signalingGO:00072679.3CGA, CGB7

Molecular functions related to Sacrococcygeal Teratoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1hormone activityGO:00051799.3CGA, CGB7

Sources for Sacrococcygeal Teratoma

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet