MCID: SCR024
MIFTS: 27

Sacrococcygeal Teratoma

Categories: Rare diseases

Aliases & Classifications for Sacrococcygeal Teratoma

MalaCards integrated aliases for Sacrococcygeal Teratoma:

Name: Sacrococcygeal Teratoma 38 50 29 69

Classifications:



Summaries for Sacrococcygeal Teratoma

NIH Rare Diseases : 50 a sacrococcygeal teratoma is a tumor that grows at the base of the spine in a developing fetus.  it occurs in one in 40,000 newborns and girls are four times more likely to be affected than boys.  though it is usually benign, there is a possibility that the teratoma could become malignant.  as such, the recommended treatment of a teratoma is complete removal of the tumor by surgery, performed soon after the birth.  if not all of the tumor is removed during the initial surgery, the teratoma may grow back (recur) and additional surgeries may be needed.  studies have found that sacrococcygeal teratomas recur in up to 22% of cases. last updated: 10/18/2013

MalaCards based summary : Sacrococcygeal Teratoma is related to teratoma and hydrops fetalis. An important gene associated with Sacrococcygeal Teratoma is MNX1 (Motor Neuron And Pancreas Homeobox 1), and among its related pathways/superpathways is Glucocorticoid receptor regulatory network. Affiliated tissues include Primitive Streak, heart and pituitary.

Wikipedia : 72 Sacrococcygeal teratoma (SCT) is a type of tumor known as a teratoma that develops at the base of the... more...

Related Diseases for Sacrococcygeal Teratoma

Diseases related to Sacrococcygeal Teratoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 64)
id Related Disease Score Top Affiliating Genes
1 teratoma 11.0
2 hydrops fetalis 10.0
3 3-methylglutaconic aciduria 9.9 CGA CGB7
4 endodermal sinus tumor 9.9
5 schinzel giedion syndrome 9.9
6 vaginitis 9.9
7 adenocarcinoma 9.9
8 fibrosarcoma 9.9
9 cardiac arrest 9.9
10 neuroblastoma 9.9
11 cornelia de lange syndrome 9.9
12 urethritis 9.9
13 ring chromosome 21 9.9
14 normokalemic periodic paralysis 9.8 AFP CGB7
15 hepatic veno-occlusive disease 9.7 AFP MNX1
16 gastroschisis 9.7
17 congestive heart failure 9.7
18 hypogonadism 9.7
19 teratoma with malignant transformation 9.7
20 hemangioma 9.7
21 weber syndrome 9.7
22 hemolytic anemia 9.7
23 fainting 9.7
24 hydrocephalus 9.7
25 trisomy 1q 9.7
26 scoliosis 9.7
27 myelocystocele 9.7
28 pseudomyxoma peritonei 9.7
29 extragonadal teratoma 9.7
30 thrombosis 9.7
31 retinitis 9.7
32 meningocele 9.7
33 congenital diaphragmatic hernia 9.7
34 hydronephrosis 9.7
35 plexiform neurofibroma 9.7
36 cauda equina syndrome 9.7
37 autoimmune hemolytic anemia 9.7
38 prune belly syndrome 9.7
39 hyperthyroidism 9.7
40 chordoma 9.7
41 neurogenic bladder 9.7
42 neurofibroma 9.7
43 currarino syndrome 9.7
44 klippel-trenaunay-weber syndrome 9.7
45 vacterl association 9.7
46 lipomyelomeningocele 9.7
47 down syndrome 9.7
48 squamous cell carcinoma 9.7
49 thoracic outlet syndrome 9.7 AFP MNX1
50 mucinous cystadenocarcinoma 9.7 CGA CGB7

Graphical network of the top 20 diseases related to Sacrococcygeal Teratoma:



Diseases related to Sacrococcygeal Teratoma

Symptoms & Phenotypes for Sacrococcygeal Teratoma

Drugs & Therapeutics for Sacrococcygeal Teratoma

Interventional clinical trials:


id Name Status NCT ID Phase Drugs
1 Characterization of At-risk Population for Pre-sacral Tumor in CURRARINO Syndrome Completed NCT00780117

Search NIH Clinical Center for Sacrococcygeal Teratoma

Genetic Tests for Sacrococcygeal Teratoma

Genetic tests related to Sacrococcygeal Teratoma:

id Genetic test Affiliating Genes
1 Sacrococcygeal Teratoma 29

Anatomical Context for Sacrococcygeal Teratoma

MalaCards organs/tissues related to Sacrococcygeal Teratoma:

39
Heart, Pituitary, Adrenal Gland, Placenta, Lung, Liver, Bone
LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Sacrococcygeal Teratoma:
id Tissue Anatomical CompartmentCell Relevance
1 Primitive Streak Primitive Streak Affected by disease

Publications for Sacrococcygeal Teratoma

Articles related to Sacrococcygeal Teratoma:

(show top 50) (show all 437)
id Title Authors Year
1
Successful Postnatal Management of Ruptured Giant Sacrococcygeal Teratoma. ( 28770134 )
2017
2
Giant sacrococcygeal teratoma: Management concerns with reporting of a rare occurrence of venous air embolism. ( 28217075 )
2017
3
Sacrococcygeal teratoma: late recurrence warrants long-term surveillance. ( 28894920 )
2017
4
Risk factors for perioperative mortality and transfusion in sacrococcygeal teratoma resections. ( 28321971 )
2017
5
Fetus in Fetu in Lieu of a Sacrococcygeal Teratoma: A Case Illuminating the Utility of Serial Prenatal Sonographic Examinations in Diagnosis. ( 28026891 )
2017
6
Pediatric Intraocular Immature Teratoma Associated With Sacrococcygeal Teratoma. ( 28521629 )
2017
7
Prune Belly Syndrome with Sacrococcygeal Teratoma. ( 28593491 )
2017
8
Early Delivery of Sacrococcygeal Teratoma with Intraspinal Extension. ( 28463844 )
2017
9
Analysis of Recurrent Sacrococcygeal Teratoma in Children: Clinical Features, Relapse Risks, and Anorectal Functional Sequelae. ( 28042962 )
2017
10
VACTERL Association with Sacrococcygeal Teratoma. ( 27567656 )
2016
11
Sacrococcygeal Teratoma associated with Trisomy 13. ( 27398323 )
2016
12
Hemorrhage is the most common cause of neonatal mortality in patients with sacrococcygeal teratoma. ( 27502009 )
2016
13
Benign sacrococcygeal teratoma incidentally found on routine scoliosis radiographs in a 12-year-old female: a case report. ( 27069263 )
2016
14
Patient-Reported Defecation and Micturition Problems Among Adults Treated for Sacrococcygeal Teratoma During Childhood-The Need for New Surveillance Strategies. ( 26739142 )
2016
15
Use of intraoperative lateral pelvic X-ray to localize and ensure coccyx removal during sacrococcygeal teratoma resection. ( 27858188 )
2016
16
Evaluation of chemotherapeutic sequelae and quality of life in survivors of malignant sacrococcygeal teratoma. ( 26667016 )
2016
17
Pediatric intraocular immature teratoma associated with sacrococcygeal teratoma: case report and review of the literature. ( 27385488 )
2016
18
Type IV Sacrococcygeal Teratoma Displacing the Urinary Bladder: Unique Magnetic Resonance Imaging. ( 27413571 )
2016
19
Sacrococcygeal Teratoma: Mistreated With Repeated Aspirations. ( 27398327 )
2016
20
Acardiac twin pregnancies part II: Fetal risk of chorangioma and sacrococcygeal teratoma predicted by pump/acardiac umbilical vein diameters. ( 27273226 )
2016
21
Hydrocephalus secondary to chemotherapy in a case of prenatally diagnosed giant immature grade 3 sacrococcygeal teratoma: A case report and literature review. ( 27787388 )
2016
22
Anaesthestic management of sacrococcygeal teratoma in infants. ( 27212735 )
2016
23
Prenatal diagnosis of tethered spinal cord associated with sacrococcygeal teratoma. ( 26892808 )
2016
24
Sacrococcygeal teratoma with intradural extension: case report. ( 25612665 )
2015
25
Multi-stage resection and repair for the treatment of adult giant sacrococcygeal teratoma: A case report and literature review. ( 26171044 )
2015
26
A review of pregnancies complicated by congenital sacrococcygeal teratoma in the West Midlands region over an 18-year period: population-based, cohort study. ( 26114890 )
2015
27
Cornelia de Lange syndrome due to mosaic NIPBL mutation: antenatal presentation with sacrococcygeal teratoma. ( 26276849 )
2015
28
Sacrococcygeal Teratoma with Yolk Sac Component in a Neonate. ( 26290815 )
2015
29
Benign and Infected Sacrococcygeal Teratoma in a 13-year-old Girl. ( 26064810 )
2015
30
Quality of life in adulthood after resection of a sacrococcygeal teratoma in childhood: a Dutch multicentre study. ( 25634960 )
2015
31
Sacrococcygeal teratoma: A population-based study of incidence and prenatal prognostic factors. ( 26454470 )
2015
32
Malignant transformation in sacrococcygeal teratoma and in presacral teratoma associated with Currarino syndrome: a comparative study. ( 25746708 )
2015
33
Laparoscopic Approach to Type IV Sacrococcygeal Teratoma in an Adult. ( 25972646 )
2015
34
A Huge Fetal Sacrococcygeal Teratoma with a Vascular Disruption Sequence. ( 26029981 )
2015
35
Sacrococcygeal teratoma in a female newborn with clinical features of trisomy 13: a case report from Central Africa. ( 26715863 )
2015
36
The first description of metyrapone use in severe Cushing Syndrome due to ectopic ACTH secretion in an infant with immature sacrococcygeal teratoma. Case Report. ( 26859587 )
2015
37
Sacrococcygeal teratoma: case report. ( 26079985 )
2015
38
Sacrococcygeal teratoma with ectopic immature renal tissue. ( 25673616 )
2015
39
Sacrococcygeal teratoma with complete adrenal gland. ( 26881658 )
2015
40
Adult Sacrococcygeal Teratoma: The third leg: A rare case report in a 25 year old man. ( 26275739 )
2015
41
Sexual function after treatment for sacrococcygeal teratoma during childhood. ( 26460155 )
2015
42
Sonographic features of congenital infantile fibrosarcoma that appeared as a sacrococcygeal teratoma during pregnancy. ( 26013636 )
2015
43
Predictors of poor prognosis in prenatally diagnosed sacrococcygeal teratoma: A multiinstitutional review. ( 25783370 )
2015
44
Re: minimally invasive therapy for fetal sacrococcygeal teratoma: case series and systematic review of the literature. T. Van Mieghem, A. Al-Ibrahim, J. Deprest, L. Lewi, J. C. Langer, D. Baud, K. O'Brien, R. Beecroft, R. Chaturvedi, E. Jaeggi, J. Fish and G. Ryan. Ultrasound Obstet Gynecol 2014; 43: 611-619. ( 24888741 )
2014
45
Analysis of recurrence risks for sacrococcygeal teratoma in children. ( 25487496 )
2014
46
Increased incidence of retroperitoneal teratomas and decreased incidence of sacrococcygeal teratomas in infants with Down syndrome. ( 23904199 )
2014
47
Sacrococcygeal teratoma growth rate predicts adverse outcomes. ( 24888848 )
2014
48
Turnbull-Cutait abdominoperineal pull-through: a safe approach for recurrent sacrococcygeal teratoma complicated by rectovaginal fistula. ( 24599763 )
2014
49
Management of preterm giant sacrococcygeal teratoma (GSCT) with an excellent outcome. ( 25480837 )
2014
50
Diagnosis of sacrococcygeal teratoma using two and three-dimensional ultrasonography: two cases reported and a literature review. ( 25110773 )
2014

Variations for Sacrococcygeal Teratoma

Expression for Sacrococcygeal Teratoma

Search GEO for disease gene expression data for Sacrococcygeal Teratoma.

Pathways for Sacrococcygeal Teratoma

Pathways related to Sacrococcygeal Teratoma according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 10.54 AFP CGA

GO Terms for Sacrococcygeal Teratoma

Biological processes related to Sacrococcygeal Teratoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cell-cell signaling GO:0007267 8.62 CGA CGB7

Molecular functions related to Sacrococcygeal Teratoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 8.62 CGA CGB7

Sources for Sacrococcygeal Teratoma

3 CDC
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10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
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32 HPO
33 ICD10
34 ICD10 via Orphanet
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36 IUPHAR
37 KEGG
38 LifeMap
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43 MESH via Orphanet
44 MGI
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48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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