MCID: SGT001
MIFTS: 50

Sagittal Sinus Thrombosis malady

Cardiovascular diseases, Blood diseases categories
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Summaries for Sagittal Sinus Thrombosis

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Wikipedia:65 Cerebral venous sinus thrombosis (CVST) is the presence of thrombosis (a blood clot) in the dural venous... more...

MalaCards based summary: Sagittal Sinus Thrombosis, also known as thrombosis of superior longitudinal sinus, is related to homocystinuria and purpura. An important gene associated with Sagittal Sinus Thrombosis is SERPINC1 (serpin peptidase inhibitor, clade C (antithrombin), member 1), and among its related pathways are Response to elevated platelet cytosolic Ca2+ and Hemostasis. The compounds hirugen and nafamostat mesilate have been mentioned in the context of this disorder. Affiliated tissues include brain, bone marrow and bone, and related mouse phenotypes are liver/biliary system and integument.

Aliases & Classifications for Sagittal Sinus Thrombosis

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Sagittal Sinus Thrombosis, Aliases & Descriptions:

Name: Sagittal Sinus Thrombosis 8 10 44 62
Thrombosis of Superior Longitudinal Sinus 8 62
 
Thrombosis of Superior Sagittal Sinus 8 62
Thrombosis Superior Sagittal Sinus 44


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Cardiovascular diseases, Blood diseases


External Ids:

Disease Ontology8 DOID:3576
SNOMED-CT57 192760003, 70607008
MeSH34 D020225

Related Diseases for Sagittal Sinus Thrombosis

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Diseases related to Sagittal Sinus Thrombosis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 112)
idRelated DiseaseScoreTop Affiliating Genes
1homocystinuria30.9F5, SERPINC1
2purpura30.9SERPINC1
3hypertension30.8PROS1, F5
4protein c deficiency30.5SERPINC1, PROS1, F5
5thrombocytopenia30.4F5, F3, SERPINC1
6protein s deficiency30.4F5, F3, PROS1, SERPINC1
7antithrombin iii deficiency30.3SERPINC1, PROS1, F5
8thromboembolism30.1SERPINC1, F3, F5
9pulmonary embolism30.0F5, F3, PROS1, SERPINC1
10antiphospholipid syndrome29.8SERPINC1, PROS1, F3, F5
11venous thrombosis29.7SERPINC1, PROS1, F3, F5
12lupus erythematosus29.7F5, F3, PROS1, SERPINC1
13nephrotic syndrome10.7
14head injury10.6
15cerebritis10.6
16headache10.6
17intracranial hypertension10.5
18leukemia10.5
19ulcerative colitis10.5
20colitis10.5
21sneddon syndrome10.4SERPINC1
22acute lymphoblastic leukemia10.4
23cortical blindness10.4
24hyperthyroidism10.4
25lymphoblastic leukemia10.4
26thyrotoxicosis10.4
27heparin-induced thrombocytopenia10.4
28blindness10.4
29branch retinal artery occlusion10.4F5
30eclampsia10.4SERPINC1
31central retinal vein occlusion10.3F5
32carotid artery thrombosis10.3F3
33deficiency anemia10.2
34aplastic anemia10.2
35arteriovenous fistula10.2
36b-cell lymphomas10.2
37behcet's disease10.2
38burkitt's lymphoma10.2
39cerebral hemorrhage10.2
40crohn's disease10.2
41hydrocephalus10.2
42lymphoblastic lymphoma10.2
43myelodysplastic syndromes10.2
44paroxysmal nocturnal hemoglobinuria10.2
45sinusitis10.2
46systemic lupus erythematosus10.2
47down syndrome10.2
48hemoglobinuria10.2
49acquired immunodeficiency syndrome10.2
50tetralogy of fallot10.2

Graphical network of the top 20 diseases related to Sagittal Sinus Thrombosis:



Diseases related to sagittal sinus thrombosis

Symptoms for Sagittal Sinus Thrombosis

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Drugs & Therapeutics for Sagittal Sinus Thrombosis

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Drug clinical trials:

Search ClinicalTrials for Sagittal Sinus Thrombosis

Search NIH Clinical Center for Sagittal Sinus Thrombosis

Genetic Tests for Sagittal Sinus Thrombosis

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Anatomical Context for Sagittal Sinus Thrombosis

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MalaCards organs/tissues related to Sagittal Sinus Thrombosis:

32
Brain, Bone marrow, Bone, Myeloid, T cells, B cells

Animal Models for Sagittal Sinus Thrombosis or affiliated genes

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MGI Mouse Phenotypes related to Sagittal Sinus Thrombosis:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053708.7F5, PROS1, SERPINC1
2MP:00107718.5F5, F3, PROS1
3MP:00053808.1F5, F3, PROS1, SERPINC1
4MP:00053858.1SERPINC1, PROS1, F3, F5
5MP:00036318.1F5, F3, PROS1, SERPINC1
6MP:00053768.0SERPINC1, PROS1, F3, F5
7MP:00107687.7SERPINC1, PROS1, F3, F5

Publications for Sagittal Sinus Thrombosis

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Articles related to Sagittal Sinus Thrombosis:

(show top 50)    (show all 186)
idTitleAuthorsYear
1
Right Atrial Thrombosis associated with Sagittal Sinus Thrombosis caused by Protein C-S Deficiency. (24362664)
2013
2
Acquired Pial and Dural Arteriovenous Fistulae following Superior Sagittal Sinus Thrombosis in Patients with Protein S Deficiency: A Report of Two Cases. (24162240)
2013
3
Sagittal sinus thrombosis while on tamoxifen requiring craniectomy. (22720357)
2012
4
Periorbital cellulitis, subgaleal abscess and superior sagittal sinus thrombosis: a rare combination of complications arising from unilateral frontal sinusitis. (23020898)
2012
5
Cortical blindness due to sagittal sinus thrombosis in acute lymphoblastic leukaemia. (19006563)
2009
6
Detection of superior sagittal sinus thrombosis on FDG PET. (19352280)
2009
7
Sagittal sinus thrombosis as a rare cause of postpartum headache: a case report]. (18853684)
2008
8
Bulky scalp metastasis and superior sagittal sinus thrombosis from a cervical adenocarcinoma: an unusual case. (18373834)
2008
9
Spontaneous superior sagittal sinus thrombosis secondary to type II heparin-induced thrombocytopenia presenting as an acute subarachnoid hemorrhage. (17582771)
2007
10
Superior sagittal sinus thrombosis: a rare but serious complication of hypernatremic dehydration in newborns. (17313317)
2007
11
Corpus callosum hematoma secondary to isolated inferior sagittal sinus thrombosis. (17135013)
2006
12
Recurrent sagittal sinus thrombosis occurring at high altitude during expeditions to Cho Oyu. (16805150)
2006
13
Superior sagittal sinus thrombosis in steroid-resistant nephrotic syndrome. (15797188)
2005
14
Superior sagittal sinus thrombosis, an unusual presentation of acute myeloid leukaemia: a case report. (16046766)
2005
15
Is heparin treatment the optimal management for cerebral venous thrombosis? Effect of abciximab, recombinant tissue plasminogen activator, and enoxaparin in experimentally induced superior sagittal sinus thrombosis. (15731475)
2005
16
Sagittal sinus thrombosis in a migraineur: differential diagnosis of headaches. (15255570)
2004
17
Thromboembolism after ovarian stimulation: successful management of a woman with superior sagittal sinus thrombosis after IVF and embryo transfer: case report. (14585890)
2003
18
Superior sagittal sinus thrombosis in a patient with postdural puncture headache. (12567347)
2003
19
Post-traumatic superior sagittal sinus thrombosis. Case report and analysis of the international literature. (14743123)
2003
20
Superior sagittal sinus thrombosis in a child with Down syndrome. (12654149)
2003
21
Sagittal sinus thrombosis in a teenager: homocystinuria associated with reversible antithrombin deficiency. (12162390)
2002
22
Superior sagittal sinus thrombosis and HIV. (12204043)
2002
23
Postpartum postural headache due to superior sagittal sinus thrombosis mistaken for spontaneous intracranial hypotension. (11305834)
2001
24
Superior sagittal sinus thrombosis induced by thyrotoxicosis. Case report. (11147882)
2001
25
Sagittal sinus thrombosis associated with transient free protein S deficiency after L-asparaginase treatment: case report and review of the literature. (10717401)
2000
26
Neuroradiology case of the day. Superior sagittal sinus thrombosis and infarcts. (10464815)
1999
27
Expansion of a haematoma after urokinase thrombolysis of superior sagittal sinus thrombosis. (20678374)
1997
28
Sagittal sinus thrombosis in adult minimal change nephrotic syndrome. (8846526)
1996
29
Superior sagittal sinus thrombosis in a child with nephrotic syndrome. (8703714)
1996
30
Superior sagittal sinus thrombosis and acquired free protein S deficiency in the elderly. (8571436)
1996
31
Neuroradiology case of the day. Sagittal sinus thrombosis with hemorrhagic venous infarct. (8659396)
1996
32
Sumatriptan-induced stroke in sagittal sinus thrombosis. (7909130)
1994
33
Sumatriptan-induced [correction of Sumatripan] stroke in sagittal sinus thrombosis. (7910310)
1994
34
Fatal superior sagittal sinus thrombosis associated with internal jugular vein catheterization. (8267072)
1993
35
Superior sagittal sinus thrombosis and pulmonary embolism: a syndrome rediscovered. (1455986)
1992
36
Noninvasive diagnosis of superior sagittal sinus thrombosis in a neonate. (1575843)
1992
37
Sagittal sinus thrombosis and leptomeningeal medulloblastoma. (2006021)
1991
38
Superior sagittal sinus thrombosis in blastic crisis of chronic myelogenous leukemia--a case report of a complete recovery. (1865591)
1991
39
Superior sagittal sinus thrombosis after internal jugular vein cannulation. (1931408)
1991
40
Thrombolysis for superior sagittal sinus thrombosis. (1799753)
1991
41
Cerebral venous and sagittal sinus thrombosis after transcallosal removal of a colloid cyst of the third ventricle: case report. (2320225)
1990
42
Direct thrombolytic therapy for superior sagittal sinus thrombosis. (2505559)
1989
43
Superior sagittal sinus thrombosis in Wegener's granulomatosis. (2703849)
1989
44
Superior sagittal sinus thrombosis. Still a killer. (3051676)
1988
45
Superior sagittal sinus thrombosis: neuroradiological evaluation and clinical findings. (3772409)
1986
46
Experimental production of superior sagittal sinus thrombosis in the dog. (3918416)
1985
47
Superior sagittal sinus thrombosis and essential thrombocythaemia. (6416403)
1983
48
Superior sagittal sinus thrombosis followed by subdural hematoma. (7179076)
1982
49
Nonmetastatic superior sagittal sinus thrombosis complicating systemic cancer. (285338)
1979
50
Superior Sagittal Sinus Thrombosis. (831684)
1977

Variations for Sagittal Sinus Thrombosis

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Expression for genes affiliated with Sagittal Sinus Thrombosis

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Expression patterns in normal tissues for genes affiliated with Sagittal Sinus Thrombosis

Search GEO for disease gene expression data for Sagittal Sinus Thrombosis.

Pathways for genes affiliated with Sagittal Sinus Thrombosis

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Compounds for genes affiliated with Sagittal Sinus Thrombosis

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Compounds related to Sagittal Sinus Thrombosis according to GeneCards/GeneDecks:

(show top 50)    (show all 85)
idCompoundScoreTop Affiliating Genes
1hirugen449.7F5, SERPINC1
2nafamostat mesilate449.6SERPINC1, F5
3ancrod449.6F5, SERPINC1
4celite449.5SERPINC1, F3
5certoparin449.5SERPINC1, F3
6reviparin449.5F3, SERPINC1
7dabigatran50 4410.5F3, SERPINC1
8efegatran449.5SERPINC1, F3
9polybrene449.4SERPINC1, F3
10nadroparin44 1110.4SERPINC1, F3
11hepaplastin449.4F3, SERPINC1
12organon449.4SERPINC1, F3
13tinzaparin44 1110.3SERPINC1, F3
14rivaroxaban44 1110.3F3, SERPINC1
15vitamin k144 2410.2SERPINC1, F3
16kaolin449.2F3, F5
17hydroxyethyl starch449.1SERPINC1, F3
18acenocoumarol44 50 1111.0F5, F3
19desogestrel44 1110.0SERPINC1, F5
20inogatran449.0SERPINC1, F5, F3
21ecarin449.0SERPINC1, F3, F5
22spectrozyme449.0F3, SERPINC1, F5
23danaparoid449.0F5, F3, SERPINC1
24ximelagatran44 1110.0F3, SERPINC1, F5
25heparinoids449.0F3, F5, SERPINC1
26fondaparinux448.9F5, SERPINC1, F3
27bivalirudin44 119.9F3, F5, SERPINC1
28argatroban44 119.9F3, F5, SERPINC1
29protamine sulfate448.9F3, SERPINC1, F5
30ristocetin448.9F5, F3, SERPINC1
31coumarins448.9F5, F3
32gamma-carboxyglutamic acid448.9F3, PROS1, F5
33levonorgestrel44 61 28 1111.9F5, F3, SERPINC1
34coumarin44 2 50 2411.9SERPINC1, F3, F5
35desmopressin44 61 28 1111.9F5, F3, SERPINC1
36fluorescein44 119.9F5, F3, SERPINC1
37hirudin448.9F5, F3, SERPINC1
38protamine448.9F5, SERPINC1, F3
39dermatan sulfate448.9SERPINC1, F3, F5
40dextran sulfate448.9SERPINC1, F3, F5
41warfarin44 50 24 1111.9F5, F3, SERPINC1
42kininogen448.9F5, SERPINC1, F3
43aprotinin44 119.9F5, F3, SERPINC1
44homocysteine44 249.8F3, SERPINC1, F5
45citrate448.8SERPINC1, F5, F3
46aspirin44 50 28 2411.6F5, SERPINC1, F3
47prostacyclin448.4F5, SERPINC1, F3, PROS1
48creatinine448.4F3, F5, PROS1, SERPINC1
49heparin44 28 24 1111.4F3, SERPINC1, F5, PROS1
50vegf448.3F3, F5, SERPINC1, PROS1

GO Terms for genes affiliated with Sagittal Sinus Thrombosis

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Cellular components related to Sagittal Sinus Thrombosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1platelet alpha granule lumenGO:0310939.3F5, PROS1
2blood microparticleGO:0725629.3PROS1, SERPINC1
3extracellular regionGO:0055768.8F5, PROS1, SERPINC1
4extracellular spaceGO:0056158.2SERPINC1, F3, F5

Biological processes related to Sagittal Sinus Thrombosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1platelet activationGO:0301689.3F5, PROS1
2platelet degranulationGO:0025769.2PROS1, F5
3negative regulation of endopeptidase activityGO:0109519.1PROS1, SERPINC1
4blood coagulationGO:0075968.0F5, F3, PROS1, SERPINC1

Molecular functions related to Sagittal Sinus Thrombosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protease bindingGO:0020209.1F3, SERPINC1

Products for genes affiliated with Sagittal Sinus Thrombosis

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  • Antibodies
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Sources for Sagittal Sinus Thrombosis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet