MCID: SGT001
MIFTS: 35

Sagittal Sinus Thrombosis malady

Categories: Cardiovascular diseases, Neuronal diseases, Blood diseases

Aliases & Classifications for Sagittal Sinus Thrombosis

Aliases & Descriptions for Sagittal Sinus Thrombosis:

Name: Sagittal Sinus Thrombosis 12 52 42 14 69
Thrombosis of Superior Longitudinal Sinus 12
Thrombosis of Superior Sagittal Sinus 12
Thrombosis Superior Sagittal Sinus 52

Classifications:



External Ids:

Disease Ontology 12 DOID:3576
MeSH 42 D020225
SNOMED-CT 64 192760003 70607008
UMLS 69 C0338575

Summaries for Sagittal Sinus Thrombosis

MalaCards based summary : Sagittal Sinus Thrombosis, also known as thrombosis of superior longitudinal sinus, is related to lupus erythematosus and budd-chiari syndrome. An important gene associated with Sagittal Sinus Thrombosis is SERPINC1 (Serpin Family C Member 1), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Collagen chain trimerization. Affiliated tissues include brain, myeloid and t cells, and related phenotypes are embryo and homeostasis/metabolism

Related Diseases for Sagittal Sinus Thrombosis

Diseases related to Sagittal Sinus Thrombosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 192)
id Related Disease Score Top Affiliating Genes
1 lupus erythematosus 30.0 F3 SERPINC1
2 budd-chiari syndrome 29.0 F2 F3 F5 SERPINC1
3 thrombosis 10.9
4 hereditary endotheliopathy, retinopathy, nephropathy, and stroke 10.2 F3 SERPINC1
5 nephrotic syndrome 10.2
6 protein s deficiency 10.2
7 secretory diarrhea myopathy and deafness 10.1 F3 SERPINC1
8 conjunctivochalasis 10.1 F3 SERPINC1
9 monocular exotropia 10.1 F3 SERPINC1
10 miller-dieker lissencephaly syndrome 10.1 F2 SERPINC1
11 leukemia 10.1
12 head injury 10.1
13 mixed epithelial tumor of ovary 10.1 F2 SERPINC1
14 peanut allergy 10.1 F2 SERPINC1
15 may-hegglin anomaly 10.1 F2 SERPINC1
16 septic myocarditis 10.1 F3 SERPINC1
17 schwannoma of jugular foramen 10.1 F2 SERPINC1
18 zika virus congenital syndrome 10.1 F3 SERPINC1
19 cerebellar astrocytoma 10.1 F2 SERPINC1
20 hemarthrosis 10.1 F2 F3
21 periosteal chondrosarcoma 10.1 F2 SERPINC1
22 angelucci's syndrome 10.1 F2 SERPINC1
23 alpha-2-macroglobulin deficiency 10.1 F2 F3
24 prostatic hypertrophy 10.1 F2 F3
25 ovarian papillary cystadenoma 10.1 F2 SERPINC1
26 dyskinetic cerebral palsy 10.1 F2 F3
27 sporotrichosis 10.1 F2 F3
28 chronic inflammatory demyelinating polyneuritis 10.1 F2 F3
29 seminoma 10.1 F2 F3
30 cerebritis 10.1
31 headache 10.1
32 brain stem cancer 10.1 F2 F3
33 alpha-2-plasmin inhibitor deficiency 10.1 F2 SERPINC1
34 spinocerebellar ataxia 27 10.1 F2 F3
35 mobitz type ii atrioventricular block 10.1 F2 F3
36 retinal arterial macroaneurysm with supravalvular pulmonic stenosis 10.1 F2 F3
37 ischemic optic neuropathy 10.1 F2 SERPINC1
38 stt3a-cdg and stt3b-cdg 10.0 F5 SERPINC1
39 artery disease 10.0 F2 F3
40 red color blindness 10.0 F2 F3
41 myosclerosis, congenital 10.0 F5 SERPINC1
42 pancreas adenocarcinoma 10.0 F2 SERPINC1
43 lymphoma 10.0
44 lymphoblastic leukemia 10.0
45 homocystinuria 10.0
46 intracranial hypertension 10.0
47 pyelonephritis 10.0 F2 SERPINC1
48 vulvitis 10.0 F2 F3
49 acrodysplasia with ossification abnormalities, short stature and fibular hypoplasia 10.0 F3 F5
50 depressed scar 10.0 F2 F3

Graphical network of the top 20 diseases related to Sagittal Sinus Thrombosis:



Diseases related to Sagittal Sinus Thrombosis

Symptoms & Phenotypes for Sagittal Sinus Thrombosis

MGI Mouse Phenotypes related to Sagittal Sinus Thrombosis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 embryo MP:0005380 9.26 F2 F3 F5 SERPINC1
2 homeostasis/metabolism MP:0005376 9.02 BLVRA F2 F3 F5 SERPINC1

Drugs & Therapeutics for Sagittal Sinus Thrombosis

Interventional clinical trials:


id Name Status NCT ID Phase
1 Imaging Silent Brain Infarct And Thrombosis in Acute Myocardial Infarction Recruiting NCT02917213

Search NIH Clinical Center for Sagittal Sinus Thrombosis

Cochrane evidence based reviews: sagittal sinus thrombosis

Genetic Tests for Sagittal Sinus Thrombosis

Anatomical Context for Sagittal Sinus Thrombosis

MalaCards organs/tissues related to Sagittal Sinus Thrombosis:

39
Brain, Myeloid, T Cells, Bone, B Cells, Bone Marrow

Publications for Sagittal Sinus Thrombosis

Articles related to Sagittal Sinus Thrombosis:

(show top 50) (show all 198)
id Title Authors Year
1
Multiple Dural and Pial Arteriovenous Fistulae in a Twenty-Four-Year-Old Woman in the Setting of Superior Sagittal Sinus Thrombosis: Case Report and Review of Literature. ( 27544867 )
2016
2
Superior sagittal sinus thrombosis after intrathecal chemotherapy and intravenous high-dose cytarabine in an acute myeloid leukemia case with t(8;21)(q22;q22). ( 27169454 )
2016
3
Superior sagittal sinus thrombosis in a patient with acute lymphoblastic leukemia. ( 28038855 )
2016
4
Papilledema secondary to a superior sagittal sinus thrombosis. Mantle cell lymphoma paraneoplastic syndrome. ( 26596713 )
2016
5
Treatment of the Superior Sagittal Sinus Thrombosis with the Mechanical Thrombectomy Using Stent-Retriever Device. ( 27651872 )
2016
6
Postdural Puncture Superior Sagittal Sinus Thrombosis in a Juvenile Case of Clinically Isolated Syndrome. ( 26558127 )
2015
7
Sagittal sinus thrombosis in puerperium. ( 26229306 )
2015
8
Superior sagittal sinus thrombosis as the initial presentation of renal cell carcinoma. ( 25829662 )
2015
9
Antegrade rheolytic thrombectomy and thrombolysis for superior sagittal sinus thrombosis using burr hole access. ( 24699566 )
2014
10
Antegrade rheolytic thrombectomy and thrombolysis for superior sagittal sinus thrombosis using burr hole access. ( 24692369 )
2014
11
Pseudotumor cerebri in a case of ulcerative colitis with sagittal sinus thrombosis. ( 23549165 )
2013
12
Sagittal sinus thrombosis with malignant brain oedema: pathophysiology of cortical veins after decompressive craniectomy. ( 23397272 )
2013
13
Macrocephaly-capillary malformation syndrome in a newborn with tetralogy of fallot and sagittal sinus thrombosis. ( 22451530 )
2013
14
Superior sagittal sinus thrombosis as a treatment complication of nonsyndromic KleeblattschAodel. ( 24220397 )
2013
15
Acute presentation of sagittal sinus thrombosis following closed head injury without overlying fracture. ( 23307334 )
2013
16
Transient ischaemic attack: an exceptional presenting syndrome of a superior sagittal sinus thrombosis. ( 24265341 )
2013
17
Post-traumatic sagittal sinus thrombosis: case report. ( 23588984 )
2013
18
Acquired Pial and Dural Arteriovenous Fistulae following Superior Sagittal Sinus Thrombosis in Patients with Protein S Deficiency: A Report of Two Cases. ( 24162240 )
2013
19
Right Atrial Thrombosis associated with Sagittal Sinus Thrombosis caused by Protein C-S Deficiency. ( 24362664 )
2013
20
Comparison of anticoagulation and thrombolysis treatments in a rat model of superior sagittal sinus thrombosis. ( 24195615 )
2013
21
The role of hyperthyroidism as the predisposing factor for superior sagittal sinus thrombosis. ( 23210057 )
2012
22
An unusual case of transient cortical blindness with sagittal sinus thrombosis in a case of Henoch-Schonlein purpura. ( 22864046 )
2012
23
Periorbital cellulitis, subgaleal abscess and superior sagittal sinus thrombosis: a rare combination of complications arising from unilateral frontal sinusitis. ( 23020898 )
2012
24
A novel protein S gene mutation combined with protein S Tokushima mutation in a patient with superior sagittal sinus thrombosis. ( 21647728 )
2012
25
Isolated inferior sagittal sinus thrombosis caused by a rare combination of elevated lipoprotein (a) and iron deficiency anemia. ( 23022905 )
2012
26
Sagittal sinus thrombosis while on tamoxifen requiring craniectomy. ( 22720357 )
2012
27
Superior sagittal sinus thrombosis complicating typhoid Fever in a teenager. ( 23227403 )
2012
28
Bilateral optic disc swelling as a presenting sign of superior sagittal sinus thrombosis. ( 22987907 )
2012
29
A rare complication in a child undergoing chemotherapy for acute lymphoblastic leukemia: superior sagittal sinus thrombosis. ( 21463850 )
2011
30
Pulmonary embolus from acute superior sagittal sinus thrombosis secondary to skull fracture: case report. ( 21389895 )
2011
31
A case of superior sagittal sinus thrombosis in pregnancy despite prophylactic antenatal heparin. ( 21126134 )
2010
32
Sagittal sinus thrombosis due to L-asparaginase. ( 21042505 )
2010
33
Intracranial hypertension caused by a depressed skull fracture resulting in superior sagittal sinus thrombosis in a pediatric patient: treatment with ventriculoperitoneal shunt insertion. ( 20593983 )
2010
34
Superior sagittal sinus thrombosis complicating neck dissection. ( 20298643 )
2010
35
Superior sagittal sinus thrombosis presenting as a continuous headache: a case report and review of the literature. ( 20062608 )
2009
36
Anesthesia for cesarean delivery in the term pregnant following acute onset severe intracranial superior sagittal sinus thrombosis. ( 19961118 )
2009
37
Susceptibility-weighted magnetic resonance imaging detects impaired cerebral hemodynamics in the superior sagittal sinus thrombosis--case report. ( 19556733 )
2009
38
Cortical blindness due to sagittal sinus thrombosis in acute lymphoblastic leukaemia. ( 19006563 )
2009
39
Detection of superior sagittal sinus thrombosis on FDG PET. ( 19352280 )
2009
40
Bulky scalp metastasis and superior sagittal sinus thrombosis from a cervical adenocarcinoma: an unusual case. ( 18373834 )
2008
41
Superior sagittal sinus thrombosis: subtle signs on neuroimaging. ( 18536826 )
2008
42
[Sagittal sinus thrombosis as a rare cause of postpartum headache: a case report]. ( 18853684 )
2008
43
Hyperemesis gravidarum and first trimester sagittal sinus thrombosis. ( 18604696 )
2008
44
Protein S deficiency, epileptic seizures, sagittal sinus thrombosis and hemorrhagic infarction after ingestion of dimenhydrinate. ( 18382986 )
2008
45
Superior sagittal sinus thrombosis: a rare but serious complication of hypernatremic dehydration in newborns. ( 17313317 )
2007
46
Superior sagittal sinus thrombosis and bilateral sixth-nerve palsy in a child with nephrotic syndrome. ( 17333003 )
2007
47
Spontaneous superior sagittal sinus thrombosis secondary to type II heparin-induced thrombocytopenia presenting as an acute subarachnoid hemorrhage. ( 17582771 )
2007
48
Superior sagittal sinus thrombosis caused by calvarial tuberculosis: case report. ( 17415184 )
2007
49
Superior sagittal sinus thrombosis. ( 17711081 )
2007
50
A new model of reversible superior sagittal sinus thrombosis in rats. ( 17919465 )
2007

Variations for Sagittal Sinus Thrombosis

Expression for Sagittal Sinus Thrombosis

Search GEO for disease gene expression data for Sagittal Sinus Thrombosis.

Pathways for Sagittal Sinus Thrombosis

GO Terms for Sagittal Sinus Thrombosis

Cellular components related to Sagittal Sinus Thrombosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.26 F2 F3 F5 SERPINC1
2 endoplasmic reticulum lumen GO:0005788 8.8 F2 F5 SERPINC1

Biological processes related to Sagittal Sinus Thrombosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 9.43 F2 F5 SERPINC1
2 platelet activation GO:0030168 9.32 F2 F5
3 blood coagulation GO:0007596 9.26 F2 F3 F5 SERPINC1
4 regulation of blood coagulation GO:0030193 9.16 F2 SERPINC1
5 hemostasis GO:0007599 8.92 F2 F3 F5 SERPINC1

Molecular functions related to Sagittal Sinus Thrombosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 protease binding GO:0002020 8.96 F3 SERPINC1
2 serine-type endopeptidase activity GO:0004252 8.8 F2 F3 F5

Sources for Sagittal Sinus Thrombosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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