MCID: SGT001
MIFTS: 35

Sagittal Sinus Thrombosis malady

Categories: Cardiovascular diseases, Neuronal diseases, Blood diseases

Aliases & Classifications for Sagittal Sinus Thrombosis

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Aliases & Descriptions for Sagittal Sinus Thrombosis:

Name: Sagittal Sinus Thrombosis 11 50 39 13 68
Thrombosis of Superior Longitudinal Sinus 11
 
Thrombosis of Superior Sagittal Sinus 11
Thrombosis Superior Sagittal Sinus 50

Classifications:



External Ids:

Disease Ontology11 DOID:3576
SNOMED-CT62 192760003, 70607008
MeSH39 D020225

Summaries for Sagittal Sinus Thrombosis

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MalaCards based summary: Sagittal Sinus Thrombosis, also known as thrombosis of superior longitudinal sinus, is related to lupus erythematosus and budd-chiari syndrome. An important gene associated with Sagittal Sinus Thrombosis is SERPINC1 (Serpin Family C Member 1), and among its related pathways are Response to elevated platelet cytosolic Ca2+ and Collagen chain trimerization. Affiliated tissues include brain, myeloid and b cells, and related mouse phenotypes are embryo and homeostasis/metabolism.

Related Diseases for Sagittal Sinus Thrombosis

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Diseases related to Sagittal Sinus Thrombosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 192)
idRelated DiseaseScoreTop Affiliating Genes
1lupus erythematosus30.0F3, SERPINC1
2budd-chiari syndrome29.0F2, F3, F5, SERPINC1
3thrombosis10.9
4hereditary endotheliopathy, retinopathy, nephropathy, and stroke10.2F3, SERPINC1
5nephrotic syndrome10.2
6protein s deficiency10.2
7secretory diarrhea myopathy and deafness10.1F3, SERPINC1
8conjunctivochalasis10.1F3, SERPINC1
9monocular exotropia10.1F3, SERPINC1
10miller-dieker lissencephaly syndrome10.1F2, SERPINC1
11leukemia10.1
12head injury10.1
13mixed epithelial tumor of ovary10.1F2, SERPINC1
14peanut allergy10.1F2, SERPINC1
15may-hegglin anomaly10.1F2, SERPINC1
16septic myocarditis10.1F3, SERPINC1
17schwannoma of jugular foramen10.1F2, SERPINC1
18zika virus congenital syndrome10.1F3, SERPINC1
19cerebellar astrocytoma10.1F2, SERPINC1
20hemarthrosis10.1F2, F3
21periosteal chondrosarcoma10.1F2, SERPINC1
22angelucci's syndrome10.1F2, SERPINC1
23alpha-2-macroglobulin deficiency10.1F2, F3
24prostatic hypertrophy10.1F2, F3
25ovarian papillary cystadenoma10.1F2, SERPINC1
26dyskinetic cerebral palsy10.1F2, F3
27sporotrichosis10.1F2, F3
28chronic inflammatory demyelinating polyneuritis10.1F2, F3
29seminoma10.1F2, F3
30cerebritis10.1
31headache10.1
32brain stem cancer10.1F2, F3
33alpha-2-plasmin inhibitor deficiency10.1F2, SERPINC1
34spinocerebellar ataxia 2710.1F2, F3
35mobitz type ii atrioventricular block10.1F2, F3
36retinal arterial macroaneurysm with supravalvular pulmonic stenosis10.1F2, F3
37ischemic optic neuropathy10.1F2, SERPINC1
38stt3a-cdg and stt3b-cdg10.0F5, SERPINC1
39artery disease10.0F2, F3
40red color blindness10.0F2, F3
41myosclerosis, congenital10.0F5, SERPINC1
42pancreas adenocarcinoma10.0F2, SERPINC1
43lymphoma10.0
44lymphoblastic leukemia10.0
45homocystinuria10.0
46intracranial hypertension10.0
47pyelonephritis10.0F2, SERPINC1
48vulvitis10.0F2, F3
49acrodysplasia with ossification abnormalities, short stature and fibular hypoplasia10.0F3, F5
50depressed scar10.0F2, F3

Graphical network of the top 20 diseases related to Sagittal Sinus Thrombosis:



Diseases related to sagittal sinus thrombosis

Symptoms & Phenotypes for Sagittal Sinus Thrombosis

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MGI Mouse Phenotypes related to Sagittal Sinus Thrombosis according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053808.8F2, F3, F5, SERPINC1
2MP:00053767.5BLVRA, F2, F3, F5, SERPINC1

Drugs & Therapeutics for Sagittal Sinus Thrombosis

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Interventional clinical trials:

idNameStatusNCT IDPhase
1Imaging Silent Brain Infarct And Thrombosis in Acute Myocardial InfarctionRecruitingNCT02917213

Search NIH Clinical Center for Sagittal Sinus Thrombosis


Cochrane evidence based reviews: sagittal sinus thrombosis

Genetic Tests for Sagittal Sinus Thrombosis

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Anatomical Context for Sagittal Sinus Thrombosis

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MalaCards organs/tissues related to Sagittal Sinus Thrombosis:

36
Brain, Myeloid, B cells, T cells, Bone, Bone marrow

Publications for Sagittal Sinus Thrombosis

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Articles related to Sagittal Sinus Thrombosis:

(show top 50)    (show all 198)
idTitleAuthorsYear
1
Multiple Dural and Pial Arteriovenous Fistulae in a Twenty-Four-Year-Old Woman in the Setting of Superior Sagittal Sinus Thrombosis: Case Report and Review of Literature. (27544867)
2016
2
Superior sagittal sinus thrombosis after intrathecal chemotherapy and intravenous high-dose cytarabine in an acute myeloid leukemia case with t(8;21)(q22;q22). (27169454)
2016
3
Superior sagittal sinus thrombosis in a patient with acute lymphoblastic leukemia. (28038855)
2016
4
Papilledema secondary to a superior sagittal sinus thrombosis. Mantle cell lymphoma paraneoplastic syndrome. (26596713)
2016
5
Treatment of the Superior Sagittal Sinus Thrombosis with the Mechanical Thrombectomy Using Stent-Retriever Device. (27651872)
2016
6
Postdural Puncture Superior Sagittal Sinus Thrombosis in a Juvenile Case of Clinically Isolated Syndrome. (26558127)
2015
7
Sagittal sinus thrombosis in puerperium. (26229306)
2015
8
Superior sagittal sinus thrombosis as the initial presentation of renal cell carcinoma. (25829662)
2015
9
Antegrade rheolytic thrombectomy and thrombolysis for superior sagittal sinus thrombosis using burr hole access. (24699566)
2014
10
Antegrade rheolytic thrombectomy and thrombolysis for superior sagittal sinus thrombosis using burr hole access. (24692369)
2014
11
Pseudotumor cerebri in a case of ulcerative colitis with sagittal sinus thrombosis. (23549165)
2013
12
Sagittal sinus thrombosis with malignant brain oedema: pathophysiology of cortical veins after decompressive craniectomy. (23397272)
2013
13
Macrocephaly-capillary malformation syndrome in a newborn with tetralogy of fallot and sagittal sinus thrombosis. (22451530)
2013
14
Superior sagittal sinus thrombosis as a treatment complication of nonsyndromic KleeblattschAodel. (24220397)
2013
15
Acute presentation of sagittal sinus thrombosis following closed head injury without overlying fracture. (23307334)
2013
16
Transient ischaemic attack: an exceptional presenting syndrome of a superior sagittal sinus thrombosis. (24265341)
2013
17
Post-traumatic sagittal sinus thrombosis: case report. (23588984)
2013
18
Acquired Pial and Dural Arteriovenous Fistulae following Superior Sagittal Sinus Thrombosis in Patients with Protein S Deficiency: A Report of Two Cases. (24162240)
2013
19
Right Atrial Thrombosis associated with Sagittal Sinus Thrombosis caused by Protein C-S Deficiency. (24362664)
2013
20
Comparison of anticoagulation and thrombolysis treatments in a rat model of superior sagittal sinus thrombosis. (24195615)
2013
21
The role of hyperthyroidism as the predisposing factor for superior sagittal sinus thrombosis. (23210057)
2012
22
An unusual case of transient cortical blindness with sagittal sinus thrombosis in a case of Henoch-Schonlein purpura. (22864046)
2012
23
Periorbital cellulitis, subgaleal abscess and superior sagittal sinus thrombosis: a rare combination of complications arising from unilateral frontal sinusitis. (23020898)
2012
24
A novel protein S gene mutation combined with protein S Tokushima mutation in a patient with superior sagittal sinus thrombosis. (21647728)
2012
25
Isolated inferior sagittal sinus thrombosis caused by a rare combination of elevated lipoprotein (a) and iron deficiency anemia. (23022905)
2012
26
Sagittal sinus thrombosis while on tamoxifen requiring craniectomy. (22720357)
2012
27
Superior sagittal sinus thrombosis complicating typhoid Fever in a teenager. (23227403)
2012
28
Bilateral optic disc swelling as a presenting sign of superior sagittal sinus thrombosis. (22987907)
2012
29
A rare complication in a child undergoing chemotherapy for acute lymphoblastic leukemia: superior sagittal sinus thrombosis. (21463850)
2011
30
Pulmonary embolus from acute superior sagittal sinus thrombosis secondary to skull fracture: case report. (21389895)
2011
31
A case of superior sagittal sinus thrombosis in pregnancy despite prophylactic antenatal heparin. (21126134)
2010
32
Sagittal sinus thrombosis due to L-asparaginase. (21042505)
2010
33
Intracranial hypertension caused by a depressed skull fracture resulting in superior sagittal sinus thrombosis in a pediatric patient: treatment with ventriculoperitoneal shunt insertion. (20593983)
2010
34
Superior sagittal sinus thrombosis complicating neck dissection. (20298643)
2010
35
Superior sagittal sinus thrombosis presenting as a continuous headache: a case report and review of the literature. (20062608)
2009
36
Anesthesia for cesarean delivery in the term pregnant following acute onset severe intracranial superior sagittal sinus thrombosis. (19961118)
2009
37
Susceptibility-weighted magnetic resonance imaging detects impaired cerebral hemodynamics in the superior sagittal sinus thrombosis--case report. (19556733)
2009
38
Cortical blindness due to sagittal sinus thrombosis in acute lymphoblastic leukaemia. (19006563)
2009
39
Detection of superior sagittal sinus thrombosis on FDG PET. (19352280)
2009
40
Bulky scalp metastasis and superior sagittal sinus thrombosis from a cervical adenocarcinoma: an unusual case. (18373834)
2008
41
Superior sagittal sinus thrombosis: subtle signs on neuroimaging. (18536826)
2008
42
Sagittal sinus thrombosis as a rare cause of postpartum headache: a case report]. (18853684)
2008
43
Hyperemesis gravidarum and first trimester sagittal sinus thrombosis. (18604696)
2008
44
Protein S deficiency, epileptic seizures, sagittal sinus thrombosis and hemorrhagic infarction after ingestion of dimenhydrinate. (18382986)
2008
45
Superior sagittal sinus thrombosis: a rare but serious complication of hypernatremic dehydration in newborns. (17313317)
2007
46
Superior sagittal sinus thrombosis and bilateral sixth-nerve palsy in a child with nephrotic syndrome. (17333003)
2007
47
Spontaneous superior sagittal sinus thrombosis secondary to type II heparin-induced thrombocytopenia presenting as an acute subarachnoid hemorrhage. (17582771)
2007
48
Superior sagittal sinus thrombosis caused by calvarial tuberculosis: case report. (17415184)
2007
49
Superior sagittal sinus thrombosis. (17711081)
2007
50
A new model of reversible superior sagittal sinus thrombosis in rats. (17919465)
2007

Variations for Sagittal Sinus Thrombosis

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Expression for genes affiliated with Sagittal Sinus Thrombosis

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Search GEO for disease gene expression data for Sagittal Sinus Thrombosis.

Pathways for genes affiliated with Sagittal Sinus Thrombosis

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GO Terms for genes affiliated with Sagittal Sinus Thrombosis

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Cellular components related to Sagittal Sinus Thrombosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1endoplasmic reticulum lumenGO:00057889.3F2, F5, SERPINC1
2extracellular spaceGO:00056158.1F2, F3, F5, SERPINC1

Biological processes related to Sagittal Sinus Thrombosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1regulation of blood coagulationGO:00301939.4F2, SERPINC1
2platelet activationGO:00301689.4F2, F5
3cellular protein metabolic processGO:00442679.2F2, F5, SERPINC1
4blood coagulationGO:00075968.7F2, F3, F5, SERPINC1
5hemostasisGO:00075998.6F2, F3, F5, SERPINC1

Molecular functions related to Sagittal Sinus Thrombosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1protease bindingGO:000202010.1F3, SERPINC1
2serine-type endopeptidase activityGO:00042528.5F2, F3, F5

Sources for Sagittal Sinus Thrombosis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet