MCID: SGT001
MIFTS: 40

Sagittal Sinus Thrombosis malady

Blood diseases category

Aliases & Classifications for Sagittal Sinus Thrombosis

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Sagittal Sinus Thrombosis, Aliases & Descriptions:

Name: Sagittal Sinus Thrombosis 9 11 43 60
Thrombosis of Superior Longitudinal Sinus 9
 
Thrombosis of Superior Sagittal Sinus 9
Thrombosis Superior Sagittal Sinus 43


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Blood diseases


External Ids:

Disease Ontology9 DOID:3576
SNOMED-CT55 70607008, 192760003
MeSH33 D020225

Summaries for Sagittal Sinus Thrombosis

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MalaCards based summary: Sagittal Sinus Thrombosis, also known as thrombosis of superior longitudinal sinus, is related to homocystinuria and purpura. An important gene associated with Sagittal Sinus Thrombosis is SERPINC1 (serpin peptidase inhibitor, clade C (antithrombin), member 1), and among its related pathways are Response to elevated platelet cytosolic Ca2+ and Hemostasis. The compounds hirugen and nafamostat mesilate have been mentioned in the context of this disorder. Affiliated tissues include brain, bone marrow and bone, and related mouse phenotypes are liver/biliary system and integument.

Related Diseases for Sagittal Sinus Thrombosis

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Diseases related to Sagittal Sinus Thrombosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 110)
idRelated DiseaseScoreTop Affiliating Genes
1homocystinuria30.9F5, SERPINC1
2purpura30.9SERPINC1
3budd-chiari syndrome30.6SERPINC1, F5
4protein c deficiency30.5SERPINC1, PROS1, F5
5thrombocytopenia30.4F5, F3, SERPINC1
6protein s deficiency30.4F5, F3, PROS1, SERPINC1
7pulmonary embolism30.0F5, F3, PROS1, SERPINC1
8lupus erythematosus30.0F5, F3, PROS1, SERPINC1
9antiphospholipid syndrome29.7SERPINC1, PROS1, F3, F5
10nephrotic syndrome10.7
11head injury10.6
12cerebritis10.6
13headache10.6
14leukemia10.5
15intracranial hypertension10.5
16ulcerative colitis10.5
17colitis10.5
18lymphoblastic leukemia10.5
19hepatic vein thrombosis10.4PROS1
20sneddon syndrome10.4SERPINC1
21systemic lupus erythematosus10.4
22cortical blindness10.4
23hyperthyroidism10.4
24thyrotoxicosis10.4
25heparin-induced thrombocytopenia10.4
26blindness10.4
27branch retinal artery occlusion10.4F5
28eclampsia10.4SERPINC1
29central retinal vein occlusion10.3F5
30carotid artery thrombosis10.3F3
31medulloblastoma10.2
32myelodysplastic syndrome10.2
33tetralogy of fallot10.2
34moyamoya disease10.2
35renal cell carcinoma10.2
36aplastic anemia10.2
37deficiency anemia10.2
38arteriovenous fistula10.2
39b-cell lymphomas10.2
40behcet's disease10.2
41cerebral hemorrhage10.2
42crohn's disease10.2
43hydrocephalus10.2
44lymphoblastic lymphoma10.2
45paroxysmal nocturnal hemoglobinuria10.2
46sinusitis10.2
47evans' syndrome10.2
48iron deficiency anemia10.2
49acquired immunodeficiency syndrome10.2
50pseudotumor cerebri10.2

Graphical network of the top 20 diseases related to Sagittal Sinus Thrombosis:



Diseases related to sagittal sinus thrombosis

Symptoms for Sagittal Sinus Thrombosis

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Drugs & Therapeutics for Sagittal Sinus Thrombosis

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Drug clinical trials:

Search ClinicalTrials for Sagittal Sinus Thrombosis

Search NIH Clinical Center for Sagittal Sinus Thrombosis

Genetic Tests for Sagittal Sinus Thrombosis

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Anatomical Context for Sagittal Sinus Thrombosis

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MalaCards organs/tissues related to Sagittal Sinus Thrombosis:

31
Brain, Bone marrow, Bone, Myeloid, T cells, B cells

Animal Models for Sagittal Sinus Thrombosis or affiliated genes

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MGI Mouse Phenotypes related to Sagittal Sinus Thrombosis:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053708.7F5, PROS1, SERPINC1
2MP:00107718.5PROS1, F5, F3
3MP:00053808.1PROS1, F3, F5, SERPINC1
4MP:00053858.1SERPINC1, PROS1, F3, F5
5MP:00036318.1F5, F3, PROS1, SERPINC1
6MP:00053768.0SERPINC1, PROS1, F3, F5
7MP:00107687.7F5, SERPINC1, PROS1, F3

Publications for Sagittal Sinus Thrombosis

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Articles related to Sagittal Sinus Thrombosis:

(show top 50)    (show all 189)
idTitleAuthorsYear
1
Right Atrial Thrombosis associated with Sagittal Sinus Thrombosis caused by Protein C-S Deficiency. (24362664)
2013
2
Acquired Pial and Dural Arteriovenous Fistulae following Superior Sagittal Sinus Thrombosis in Patients with Protein S Deficiency: A Report of Two Cases. (24162240)
2013
3
Sagittal sinus thrombosis while on tamoxifen requiring craniectomy. (22720357)
2012
4
Periorbital cellulitis, subgaleal abscess and superior sagittal sinus thrombosis: a rare combination of complications arising from unilateral frontal sinusitis. (23020898)
2012
5
A rare complication in a child undergoing chemotherapy for acute lymphoblastic leukemia: superior sagittal sinus thrombosis. (21463850)
2011
6
Cortical blindness due to sagittal sinus thrombosis in acute lymphoblastic leukaemia. (19006563)
2009
7
Detection of superior sagittal sinus thrombosis on FDG PET. (19352280)
2009
8
Sagittal sinus thrombosis as a rare cause of postpartum headache: a case report]. (18853684)
2008
9
Bulky scalp metastasis and superior sagittal sinus thrombosis from a cervical adenocarcinoma: an unusual case. (18373834)
2008
10
Spontaneous superior sagittal sinus thrombosis secondary to type II heparin-induced thrombocytopenia presenting as an acute subarachnoid hemorrhage. (17582771)
2007
11
Corpus callosum hematoma secondary to isolated inferior sagittal sinus thrombosis. (17135013)
2006
12
Recurrent sagittal sinus thrombosis occurring at high altitude during expeditions to Cho Oyu. (16805150)
2006
13
Superior sagittal sinus thrombosis in steroid-resistant nephrotic syndrome. (15797188)
2005
14
Superior sagittal sinus thrombosis, an unusual presentation of acute myeloid leukaemia: a case report. (16046766)
2005
15
Is heparin treatment the optimal management for cerebral venous thrombosis? Effect of abciximab, recombinant tissue plasminogen activator, and enoxaparin in experimentally induced superior sagittal sinus thrombosis. (15731475)
2005
16
Sagittal sinus thrombosis in a migraineur: differential diagnosis of headaches. (15255570)
2004
17
Thromboembolism after ovarian stimulation: successful management of a woman with superior sagittal sinus thrombosis after IVF and embryo transfer: case report. (14585890)
2003
18
Superior sagittal sinus thrombosis in a patient with postdural puncture headache. (12567347)
2003
19
Post-traumatic superior sagittal sinus thrombosis. Case report and analysis of the international literature. (14743123)
2003
20
Superior sagittal sinus thrombosis in a child with Down syndrome. (12654149)
2003
21
Sagittal sinus thrombosis in a teenager: homocystinuria associated with reversible antithrombin deficiency. (12162390)
2002
22
Superior sagittal sinus thrombosis and HIV. (12204043)
2002
23
Postpartum postural headache due to superior sagittal sinus thrombosis mistaken for spontaneous intracranial hypotension. (11305834)
2001
24
Superior sagittal sinus thrombosis induced by thyrotoxicosis. Case report. (11147882)
2001
25
Sagittal sinus thrombosis associated with transient free protein S deficiency after L-asparaginase treatment: case report and review of the literature. (10717401)
2000
26
Neuroradiology case of the day. Superior sagittal sinus thrombosis and infarcts. (10464815)
1999
27
Expansion of a haematoma after urokinase thrombolysis of superior sagittal sinus thrombosis. (20678374)
1997
28
Sagittal sinus thrombosis in adult minimal change nephrotic syndrome. (8846526)
1996
29
Superior sagittal sinus thrombosis in a child with nephrotic syndrome. (8703714)
1996
30
Superior sagittal sinus thrombosis and acquired free protein S deficiency in the elderly. (8571436)
1996
31
Neuroradiology case of the day. Sagittal sinus thrombosis with hemorrhagic venous infarct. (8659396)
1996
32
Sumatriptan-induced stroke in sagittal sinus thrombosis. (7909130)
1994
33
Sumatriptan-induced [correction of Sumatripan] stroke in sagittal sinus thrombosis. (7910310)
1994
34
Fatal superior sagittal sinus thrombosis associated with internal jugular vein catheterization. (8267072)
1993
35
Superior sagittal sinus thrombosis and pulmonary embolism: a syndrome rediscovered. (1455986)
1992
36
Noninvasive diagnosis of superior sagittal sinus thrombosis in a neonate. (1575843)
1992
37
Sagittal sinus thrombosis and leptomeningeal medulloblastoma. (2006021)
1991
38
Superior sagittal sinus thrombosis in blastic crisis of chronic myelogenous leukemia--a case report of a complete recovery. (1865591)
1991
39
Superior sagittal sinus thrombosis after internal jugular vein cannulation. (1931408)
1991
40
Thrombolysis for superior sagittal sinus thrombosis. (1799753)
1991
41
Cerebral venous and sagittal sinus thrombosis after transcallosal removal of a colloid cyst of the third ventricle: case report. (2320225)
1990
42
Direct thrombolytic therapy for superior sagittal sinus thrombosis. (2505559)
1989
43
Superior sagittal sinus thrombosis in Wegener's granulomatosis. (2703849)
1989
44
A case of thrombosed aneurysm of the vein of Galen associated with superior sagittal sinus thrombosis. (2634086)
1989
45
Superior sagittal sinus thrombosis: neuroradiological evaluation and clinical findings. (3772409)
1986
46
Experimental production of superior sagittal sinus thrombosis in the dog. (3918416)
1985
47
Superior sagittal sinus thrombosis and essential thrombocythaemia. (6416403)
1983
48
Superior sagittal sinus thrombosis followed by subdural hematoma. (7179076)
1982
49
Nonmetastatic superior sagittal sinus thrombosis complicating systemic cancer. (285338)
1979
50
Superior Sagittal Sinus Thrombosis. (831684)
1977

Variations for Sagittal Sinus Thrombosis

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Expression for genes affiliated with Sagittal Sinus Thrombosis

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Search GEO for disease gene expression data for Sagittal Sinus Thrombosis.

Pathways for genes affiliated with Sagittal Sinus Thrombosis

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Compounds for genes affiliated with Sagittal Sinus Thrombosis

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Compounds related to Sagittal Sinus Thrombosis according to GeneCards Suite gene sharing:

(show top 50)    (show all 85)
idCompoundScoreTop Affiliating Genes
1hirugen439.7SERPINC1, F5
2nafamostat mesilate439.6SERPINC1, F5
3celite439.5F3, SERPINC1
4reviparin439.5F3, SERPINC1
5certoparin439.5F3, SERPINC1
6ancrod439.5SERPINC1, F5
7efegatran439.5F3, SERPINC1
8dabigatran49 4310.5F3, SERPINC1
9polybrene439.4SERPINC1, F3
10nadroparin43 1210.4SERPINC1, F3
11hepaplastin439.4SERPINC1, F3
12rivaroxaban43 1210.4SERPINC1, F3
13tinzaparin43 1210.4SERPINC1, F3
14organon439.3SERPINC1, F3
15vitamin k143 2410.2F3, SERPINC1
16kaolin439.2F3, F5
17acenocoumarol43 49 1211.0F5, F3
18desogestrel43 1210.0F5, SERPINC1
19hydroxyethyl starch439.0F3, SERPINC1
20coumarins439.0F5, F3
21inogatran439.0F5, F3, SERPINC1
22ecarin439.0F5, F3, SERPINC1
23spectrozyme439.0SERPINC1, F3, F5
24danaparoid439.0F5, F3, SERPINC1
25ximelagatran43 1210.0F5, F3, SERPINC1
26heparinoids439.0SERPINC1, F3, F5
27fondaparinux438.9F5, F3, SERPINC1
28bivalirudin43 129.9F5, F3, SERPINC1
29argatroban43 129.9SERPINC1, F3, F5
30protamine sulfate438.9F5, F3, SERPINC1
31ristocetin438.9F5, F3, SERPINC1
32gamma-carboxyglutamic acid438.9F5, F3, PROS1
33levonorgestrel43 59 28 1211.9SERPINC1, F3, F5
34coumarin43 2 49 2411.9F5, F3, SERPINC1
35desmopressin43 59 28 1211.9F5, F3, SERPINC1
36fluorescein43 129.9SERPINC1, F3, F5
37hirudin438.9F5, F3, SERPINC1
38protamine438.9F5, F3, SERPINC1
39dermatan sulfate438.9SERPINC1, F3, F5
40dextran sulfate438.9F5, F3, SERPINC1
41warfarin43 49 24 1211.9SERPINC1, F3, F5
42kininogen438.9F5, F3, SERPINC1
43aprotinin43 129.9SERPINC1, F3, F5
44homocysteine43 249.8F5, F3, SERPINC1
45citrate438.8F5, F3, SERPINC1
46aspirin43 49 28 2411.6SERPINC1, F3, F5
47prostacyclin438.4SERPINC1, PROS1, F3, F5
48creatinine438.4SERPINC1, PROS1, F3, F5
49heparin43 28 24 1211.4SERPINC1, PROS1, F3, F5
50vegf438.3F5, F3, PROS1, SERPINC1

GO Terms for genes affiliated with Sagittal Sinus Thrombosis

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Cellular components related to Sagittal Sinus Thrombosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1platelet alpha granule lumenGO:00310939.3PROS1, F5
2blood microparticleGO:00725629.3SERPINC1, PROS1
3extracellular regionGO:00055768.8SERPINC1, PROS1, F5
4extracellular spaceGO:00056158.2SERPINC1, F3, F5

Biological processes related to Sagittal Sinus Thrombosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1platelet activationGO:00301689.3F5, PROS1
2platelet degranulationGO:00025769.2F5, PROS1
3negative regulation of endopeptidase activityGO:00109519.1PROS1, SERPINC1
4blood coagulationGO:00075968.0SERPINC1, F5, F3, PROS1

Molecular functions related to Sagittal Sinus Thrombosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1protease bindingGO:00020209.1F3, SERPINC1

Products for genes affiliated with Sagittal Sinus Thrombosis

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Sources for Sagittal Sinus Thrombosis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet