MCID: SGT001
MIFTS: 33

Sagittal Sinus Thrombosis

Categories: Cardiovascular diseases, Neuronal diseases, Blood diseases

Aliases & Classifications for Sagittal Sinus Thrombosis

MalaCards integrated aliases for Sagittal Sinus Thrombosis:

Name: Sagittal Sinus Thrombosis 12 52 42 14 69
Thrombosis of Superior Longitudinal Sinus 12
Thrombosis of Superior Sagittal Sinus 12
Thrombosis Superior Sagittal Sinus 52

Classifications:



External Ids:

Disease Ontology 12 DOID:3576
MeSH 42 D020225
SNOMED-CT 64 192760003 70607008
UMLS 69 C0338575

Summaries for Sagittal Sinus Thrombosis

MalaCards based summary : Sagittal Sinus Thrombosis, also known as thrombosis of superior longitudinal sinus, is related to hyperthyroidism and budd-chiari syndrome. An important gene associated with Sagittal Sinus Thrombosis is SERPINC1 (Serpin Family C Member 1), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Collagen chain trimerization. Affiliated tissues include brain, myeloid and b cells, and related phenotype is embryo.

Related Diseases for Sagittal Sinus Thrombosis

Diseases related to Sagittal Sinus Thrombosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 190)
id Related Disease Score Top Affiliating Genes
1 hyperthyroidism 30.1 F2 F3
2 budd-chiari syndrome 28.0 F2 F3 F5 SERPINC1
3 thrombosis 10.9
4 hereditary amyloidosis 10.4 F3 SERPINC1
5 chronic diarrhea due to guanylate cyclase 2c overactivity 10.3 F3 SERPINC1
6 monocular exotropia 10.3 F3 SERPINC1
7 coronary stenosis 10.3 F3 SERPINC1
8 parasitic helminthiasis infectious disease 10.3 F3 SERPINC1
9 fiedler's myocarditis 10.2 F3 SERPINC1
10 egg allergy 10.2 F2 SERPINC1
11 syndactyly, mesoaxial synostotic, with phalangeal reduction 10.2 F2 SERPINC1
12 littre gland carcinoma 10.2 F2 SERPINC1
13 haemophilus meningitis 10.2 F3 SERPINC1
14 pilomyxoid astrocytoma 10.2 F2 SERPINC1
15 inferolateral myocardial infarct 10.2 F2 SERPINC1
16 angelucci's syndrome 10.2 F2 SERPINC1
17 childhood brain stem glioma 10.2 F2 SERPINC1
18 von willibrand disease, type 3 10.2 F2 F3
19 female breast cancer 10.2 F2 F3
20 brain stem glioma 10.2 F2 F3
21 nephrotic syndrome 10.2
22 protein s deficiency 10.2
23 sporotrichosis 10.2 F2 F3
24 central nervous system germ cell tumor 10.2 F2 F3
25 chronic inflammatory demyelinating polyneuritis 10.1 F2 F3
26 leukemia 10.1
27 head injury 10.1
28 red color blindness 10.1 F2 F3
29 hyperphenylalaninemia 10.1 F2 F3
30 microcephaly 8, primary, autosomal recessive 10.1 F2 F3
31 bernard-soulier syndrome, type a2 10.1 F2 SERPINC1
32 rheumatic heart disease 10.1 F2 F3
33 ischemic heart disease 10.1 F2 SERPINC1
34 cerebritis 10.1
35 headache 10.1
36 ovarian insufficiency, familial 10.1 F2 SERPINC1
37 factor x deficiency 10.1 F2 F3
38 van maldergem syndrome 2 10.0 F2 F3
39 stoll alembik finck syndrome 10.0 F5 SERPINC1
40 lymphoma 10.0
41 lymphoblastic leukemia 10.0
42 homocystinuria 10.0
43 intracranial hypertension 10.0
44 pyelonephritis 10.0 F2 SERPINC1
45 dentinogenesis imperfecta 10.0 F2 F3
46 hidradenoma 10.0 F2 F3
47 mixed mineral dust pneumoconiosis 10.0 F2 SERPINC1
48 mental retardation dysmorphism hypogonadism diabetes 10.0 F5 SERPINC1
49 acquired von willebrand syndrome 10.0 F3 F5
50 acquired pure red cell aplasia 10.0 F3 F5

Graphical network of the top 20 diseases related to Sagittal Sinus Thrombosis:



Diseases related to Sagittal Sinus Thrombosis

Symptoms & Phenotypes for Sagittal Sinus Thrombosis

MGI Mouse Phenotypes related to Sagittal Sinus Thrombosis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 embryo MP:0005380 8.92 F2 F3 F5 SERPINC1

Drugs & Therapeutics for Sagittal Sinus Thrombosis

Interventional clinical trials:


id Name Status NCT ID Phase Drugs
1 Imaging Silent Brain Infarct And Thrombosis in Acute Myocardial Infarction Recruiting NCT02917213

Search NIH Clinical Center for Sagittal Sinus Thrombosis

Cochrane evidence based reviews: sagittal sinus thrombosis

Genetic Tests for Sagittal Sinus Thrombosis

Anatomical Context for Sagittal Sinus Thrombosis

MalaCards organs/tissues related to Sagittal Sinus Thrombosis:

39
Brain, Myeloid, B Cells, T Cells, Bone, Bone Marrow

Publications for Sagittal Sinus Thrombosis

Articles related to Sagittal Sinus Thrombosis:

(show top 50) (show all 200)
id Title Authors Year
1
Congenital dysfibrinogenemia in a Japanese family with fibrinogen Naples (BI^Ala68Thr) manifesting as superior sagittal sinus thrombosis. ( 28537987 )
2017
2
Sagittal sinus thrombosis in JAK2-V617F mutation without overt myeloproliferative disorder. ( 28228434 )
2017
3
Multiple Dural and Pial Arteriovenous Fistulae in a Twenty-Four-Year-Old Woman in the Setting of Superior Sagittal Sinus Thrombosis: Case Report and Review of Literature. ( 27544867 )
2016
4
Papilledema secondary to a superior sagittal sinus thrombosis. Mantle cell lymphoma paraneoplastic syndrome. ( 26596713 )
2016
5
Superior sagittal sinus thrombosis in a patient with acute lymphoblastic leukemia. ( 28038855 )
2016
6
Superior sagittal sinus thrombosis after intrathecal chemotherapy and intravenous high-dose cytarabine in an acute myeloid leukemia case with t(8;21)(q22;q22). ( 27169454 )
2016
7
Treatment of the Superior Sagittal Sinus Thrombosis with the Mechanical Thrombectomy Using Stent-Retriever Device. ( 27651872 )
2016
8
Sagittal sinus thrombosis in puerperium. ( 26229306 )
2015
9
Superior sagittal sinus thrombosis as the initial presentation of renal cell carcinoma. ( 25829662 )
2015
10
Postdural Puncture Superior Sagittal Sinus Thrombosis in a Juvenile Case of Clinically Isolated Syndrome. ( 26558127 )
2015
11
Antegrade rheolytic thrombectomy and thrombolysis for superior sagittal sinus thrombosis using burr hole access. ( 24692369 )
2014
12
Antegrade rheolytic thrombectomy and thrombolysis for superior sagittal sinus thrombosis using burr hole access. ( 24699566 )
2014
13
Comparison of anticoagulation and thrombolysis treatments in a rat model of superior sagittal sinus thrombosis. ( 24195615 )
2013
14
Acquired Pial and Dural Arteriovenous Fistulae following Superior Sagittal Sinus Thrombosis in Patients with Protein S Deficiency: A Report of Two Cases. ( 24162240 )
2013
15
Acute presentation of sagittal sinus thrombosis following closed head injury without overlying fracture. ( 23307334 )
2013
16
Transient ischaemic attack: an exceptional presenting syndrome of a superior sagittal sinus thrombosis. ( 24265341 )
2013
17
Superior sagittal sinus thrombosis as a treatment complication of nonsyndromic KleeblattschAodel. ( 24220397 )
2013
18
Right Atrial Thrombosis associated with Sagittal Sinus Thrombosis caused by Protein C-S Deficiency. ( 24362664 )
2013
19
Macrocephaly-capillary malformation syndrome in a newborn with tetralogy of fallot and sagittal sinus thrombosis. ( 22451530 )
2013
20
Post-traumatic sagittal sinus thrombosis: case report. ( 23588984 )
2013
21
Sagittal sinus thrombosis with malignant brain oedema: pathophysiology of cortical veins after decompressive craniectomy. ( 23397272 )
2013
22
Pseudotumor cerebri in a case of ulcerative colitis with sagittal sinus thrombosis. ( 23549165 )
2013
23
An unusual case of transient cortical blindness with sagittal sinus thrombosis in a case of Henoch-Schonlein purpura. ( 22864046 )
2012
24
Superior sagittal sinus thrombosis complicating typhoid Fever in a teenager. ( 23227403 )
2012
25
The role of hyperthyroidism as the predisposing factor for superior sagittal sinus thrombosis. ( 23210057 )
2012
26
Periorbital cellulitis, subgaleal abscess and superior sagittal sinus thrombosis: a rare combination of complications arising from unilateral frontal sinusitis. ( 23020898 )
2012
27
Sagittal sinus thrombosis while on tamoxifen requiring craniectomy. ( 22720357 )
2012
28
Isolated inferior sagittal sinus thrombosis caused by a rare combination of elevated lipoprotein (a) and iron deficiency anemia. ( 23022905 )
2012
29
A novel protein S gene mutation combined with protein S Tokushima mutation in a patient with superior sagittal sinus thrombosis. ( 21647728 )
2012
30
Bilateral optic disc swelling as a presenting sign of superior sagittal sinus thrombosis. ( 22987907 )
2012
31
Pulmonary embolus from acute superior sagittal sinus thrombosis secondary to skull fracture: case report. ( 21389895 )
2011
32
A rare complication in a child undergoing chemotherapy for acute lymphoblastic leukemia: superior sagittal sinus thrombosis. ( 21463850 )
2011
33
Intracranial hypertension caused by a depressed skull fracture resulting in superior sagittal sinus thrombosis in a pediatric patient: treatment with ventriculoperitoneal shunt insertion. ( 20593983 )
2010
34
A case of superior sagittal sinus thrombosis in pregnancy despite prophylactic antenatal heparin. ( 21126134 )
2010
35
Superior sagittal sinus thrombosis complicating neck dissection. ( 20298643 )
2010
36
Sagittal sinus thrombosis due to L-asparaginase. ( 21042505 )
2010
37
Susceptibility-weighted magnetic resonance imaging detects impaired cerebral hemodynamics in the superior sagittal sinus thrombosis--case report. ( 19556733 )
2009
38
Superior sagittal sinus thrombosis presenting as a continuous headache: a case report and review of the literature. ( 20062608 )
2009
39
Detection of superior sagittal sinus thrombosis on FDG PET. ( 19352280 )
2009
40
Anesthesia for cesarean delivery in the term pregnant following acute onset severe intracranial superior sagittal sinus thrombosis. ( 19961118 )
2009
41
Cortical blindness due to sagittal sinus thrombosis in acute lymphoblastic leukaemia. ( 19006563 )
2009
42
Hyperemesis gravidarum and first trimester sagittal sinus thrombosis. ( 18604696 )
2008
43
Superior sagittal sinus thrombosis: subtle signs on neuroimaging. ( 18536826 )
2008
44
Protein S deficiency, epileptic seizures, sagittal sinus thrombosis and hemorrhagic infarction after ingestion of dimenhydrinate. ( 18382986 )
2008
45
[Sagittal sinus thrombosis as a rare cause of postpartum headache: a case report]. ( 18853684 )
2008
46
Bulky scalp metastasis and superior sagittal sinus thrombosis from a cervical adenocarcinoma: an unusual case. ( 18373834 )
2008
47
Spontaneous superior sagittal sinus thrombosis secondary to type II heparin-induced thrombocytopenia presenting as an acute subarachnoid hemorrhage. ( 17582771 )
2007
48
A new model of reversible superior sagittal sinus thrombosis in rats. ( 17919465 )
2007
49
Superior sagittal sinus thrombosis. ( 17711081 )
2007
50
Superior sagittal sinus thrombosis: a rare but serious complication of hypernatremic dehydration in newborns. ( 17313317 )
2007

Variations for Sagittal Sinus Thrombosis

Expression for Sagittal Sinus Thrombosis

Search GEO for disease gene expression data for Sagittal Sinus Thrombosis.

Pathways for Sagittal Sinus Thrombosis

GO Terms for Sagittal Sinus Thrombosis

Cellular components related to Sagittal Sinus Thrombosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.26 F2 F3 F5 SERPINC1
2 endoplasmic reticulum lumen GO:0005788 8.8 F2 F5 SERPINC1

Biological processes related to Sagittal Sinus Thrombosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 9.33 F2 F5 SERPINC1
2 regulation of blood coagulation GO:0030193 9.26 F2 SERPINC1
3 blood coagulation GO:0007596 9.26 F2 F3 F5 SERPINC1
4 hemostasis GO:0007599 8.92 F2 F3 F5 SERPINC1

Molecular functions related to Sagittal Sinus Thrombosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 protease binding GO:0002020 8.62 F3 SERPINC1

Sources for Sagittal Sinus Thrombosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....