MCID: SGT001
MIFTS: 34

Sagittal Sinus Thrombosis

Categories: Blood diseases, Cardiovascular diseases

Aliases & Classifications for Sagittal Sinus Thrombosis

MalaCards integrated aliases for Sagittal Sinus Thrombosis:

Name: Sagittal Sinus Thrombosis 12 51 69 41 14
Thrombosis of Superior Longitudinal Sinus 12
Thrombosis of Superior Sagittal Sinus 12
Thrombosis Superior Sagittal Sinus 51

Classifications:



External Ids:

Disease Ontology 12 DOID:3576
MeSH 41 D020225
SNOMED-CT 64 192760003 70607008
UMLS 69 C0338575

Summaries for Sagittal Sinus Thrombosis

MalaCards based summary : Sagittal Sinus Thrombosis, also known as thrombosis of superior longitudinal sinus, is related to thrombosis and heparin-induced thrombocytopenia. An important gene associated with Sagittal Sinus Thrombosis is SERPINC1 (Serpin Family C Member 1), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Collagen chain trimerization. Affiliated tissues include brain, myeloid and b cells.

Related Diseases for Sagittal Sinus Thrombosis

Diseases related to Sagittal Sinus Thrombosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 190)
# Related Disease Score Top Affiliating Genes
1 thrombosis 30.7 F2 F3 F5 SERPINC1
2 heparin-induced thrombocytopenia 30.4 F3 SERPINC1
3 homocystinuria 29.8 F5 SERPINC1
4 protein c deficiency 29.7 F2 F5 SERPINC1
5 protein s deficiency 29.6 F2 F3 F5 SERPINC1
6 purpura 29.6 F2 F3 SERPINC1
7 antithrombin iii deficiency 29.4 F2 F5 SERPINC1
8 dysfibrinogenemia 29.4 F2 F5 SERPINC1
9 intracranial hypertension 29.4 F2 F3 F5 SERPINC1
10 pulmonary embolism 29.2 F2 F3 F5 SERPINC1
11 thrombophilia due to thrombin defect 29.0 F2 F3 F5 SERPINC1
12 budd-chiari syndrome 29.0 F2 F3 F5 SERPINC1
13 antiphospholipid syndrome 29.0 F2 F3 F5 SERPINC1
14 complement hyperactivation, angiopathic thrombosis, and protein-losing enteropathy 11.0
15 angina pectoris 10.2 F3 SERPINC1
16 nephrotic syndrome 10.2
17 blood protein disease 10.2 F2 SERPINC1
18 alpha-2-plasmin inhibitor deficiency 10.2 F2 SERPINC1
19 coronary thrombosis 10.2 F3 SERPINC1
20 leukemia 10.2
21 head injury 10.2
22 anterior spinal artery syndrome 10.2 F2 SERPINC1
23 cerebral falx meningioma 10.2 F2 F3
24 intermediate coronary syndrome 10.2 F3 SERPINC1
25 subendocardial myocardial infarction 10.2 F2 SERPINC1
26 von willebrand disease, type 1 10.2 F2 F3
27 qualitative platelet defect 10.2 F2 F3
28 esophageal varix 10.2 F2 SERPINC1
29 femoral neuropathy 10.2 F2 F3
30 alcohol-related birth defect 10.2 F2 F3
31 hantavirus pulmonary syndrome 10.2 F2 F3
32 hypersplenism 10.2 F2 SERPINC1
33 anterior cranial fossa meningioma 10.2 F2 F3
34 pulmonary immaturity 10.2 F3 SERPINC1
35 cerebritis 10.2
36 headache 10.2
37 splenic disease 10.2 F2 F3
38 sticky platelet syndrome 10.2 F5 SERPINC1
39 hepatic veno-occlusive disease 10.2 F3 SERPINC1
40 squamous cell papilloma 10.1 F2 F3
41 hemophilia 10.1 F2 F3
42 acquired hemophilia a 10.1 F3 F5
43 acquired hemophilia 10.1 F3 F5
44 lymphoma 10.1
45 lymphoblastic leukemia 10.1
46 meningococcemia 10.1 F5 SERPINC1
47 analbuminemia 10.1 F2 F3
48 endocardium disease 10.1 F2 F3
49 catastrophic antiphospholipid syndrome 10.1 F3 F5
50 intermittent claudication 10.1 F2 SERPINC1

Graphical network of the top 20 diseases related to Sagittal Sinus Thrombosis:



Diseases related to Sagittal Sinus Thrombosis

Symptoms & Phenotypes for Sagittal Sinus Thrombosis

Drugs & Therapeutics for Sagittal Sinus Thrombosis

Search Clinical Trials , NIH Clinical Center for Sagittal Sinus Thrombosis

Cochrane evidence based reviews: sagittal sinus thrombosis

Genetic Tests for Sagittal Sinus Thrombosis

Anatomical Context for Sagittal Sinus Thrombosis

MalaCards organs/tissues related to Sagittal Sinus Thrombosis:

38
Brain, Myeloid, B Cells, T Cells, Bone, Bone Marrow

Publications for Sagittal Sinus Thrombosis

Articles related to Sagittal Sinus Thrombosis:

(show top 50) (show all 200)
# Title Authors Year
1
Sagittal sinus thrombosis in JAK2-V617F mutation without overt myeloproliferative disorder. ( 28228434 )
2017
2
Congenital dysfibrinogenemia in a Japanese family with fibrinogen Naples (BI^Ala68Thr) manifesting as superior sagittal sinus thrombosis. ( 28537987 )
2017
3
Treatment of the Superior Sagittal Sinus Thrombosis with the Mechanical Thrombectomy Using Stent-Retriever Device. ( 27651872 )
2016
4
Superior sagittal sinus thrombosis in a patient with acute lymphoblastic leukemia. ( 28038855 )
2016
5
Multiple Dural and Pial Arteriovenous Fistulae in a Twenty-Four-Year-Old Woman in the Setting of Superior Sagittal Sinus Thrombosis: Case Report and Review of Literature. ( 27544867 )
2016
6
Papilledema secondary to a superior sagittal sinus thrombosis. Mantle cell lymphoma paraneoplastic syndrome. ( 26596713 )
2016
7
Superior sagittal sinus thrombosis after intrathecal chemotherapy and intravenous high-dose cytarabine in an acute myeloid leukemia case with t(8;21)(q22;q22). ( 27169454 )
2016
8
Sagittal sinus thrombosis in puerperium. ( 26229306 )
2015
9
Superior sagittal sinus thrombosis as the initial presentation of renal cell carcinoma. ( 25829662 )
2015
10
Postdural Puncture Superior Sagittal Sinus Thrombosis in a Juvenile Case of Clinically Isolated Syndrome. ( 26558127 )
2015
11
Antegrade rheolytic thrombectomy and thrombolysis for superior sagittal sinus thrombosis using burr hole access. ( 24692369 )
2014
12
Antegrade rheolytic thrombectomy and thrombolysis for superior sagittal sinus thrombosis using burr hole access. ( 24699566 )
2014
13
Comparison of anticoagulation and thrombolysis treatments in a rat model of superior sagittal sinus thrombosis. ( 24195615 )
2013
14
Superior sagittal sinus thrombosis as a treatment complication of nonsyndromic KleeblattschAodel. ( 24220397 )
2013
15
Transient ischaemic attack: an exceptional presenting syndrome of a superior sagittal sinus thrombosis. ( 24265341 )
2013
16
Pseudotumor cerebri in a case of ulcerative colitis with sagittal sinus thrombosis. ( 23549165 )
2013
17
Post-traumatic sagittal sinus thrombosis: case report. ( 23588984 )
2013
18
Acquired Pial and Dural Arteriovenous Fistulae following Superior Sagittal Sinus Thrombosis in Patients with Protein S Deficiency: A Report of Two Cases. ( 24162240 )
2013
19
Sagittal sinus thrombosis with malignant brain oedema: pathophysiology of cortical veins after decompressive craniectomy. ( 23397272 )
2013
20
Right Atrial Thrombosis associated with Sagittal Sinus Thrombosis caused by Protein C-S Deficiency. ( 24362664 )
2013
21
Macrocephaly-capillary malformation syndrome in a newborn with tetralogy of fallot and sagittal sinus thrombosis. ( 22451530 )
2013
22
Acute presentation of sagittal sinus thrombosis following closed head injury without overlying fracture. ( 23307334 )
2013
23
Periorbital cellulitis, subgaleal abscess and superior sagittal sinus thrombosis: a rare combination of complications arising from unilateral frontal sinusitis. ( 23020898 )
2012
24
Sagittal sinus thrombosis while on tamoxifen requiring craniectomy. ( 22720357 )
2012
25
An unusual case of transient cortical blindness with sagittal sinus thrombosis in a case of Henoch-Schonlein purpura. ( 22864046 )
2012
26
A novel protein S gene mutation combined with protein S Tokushima mutation in a patient with superior sagittal sinus thrombosis. ( 21647728 )
2012
27
Bilateral optic disc swelling as a presenting sign of superior sagittal sinus thrombosis. ( 22987907 )
2012
28
Superior sagittal sinus thrombosis complicating typhoid Fever in a teenager. ( 23227403 )
2012
29
The role of hyperthyroidism as the predisposing factor for superior sagittal sinus thrombosis. ( 23210057 )
2012
30
Isolated inferior sagittal sinus thrombosis caused by a rare combination of elevated lipoprotein (a) and iron deficiency anemia. ( 23022905 )
2012
31
A rare complication in a child undergoing chemotherapy for acute lymphoblastic leukemia: superior sagittal sinus thrombosis. ( 21463850 )
2011
32
Pulmonary embolus from acute superior sagittal sinus thrombosis secondary to skull fracture: case report. ( 21389895 )
2011
33
Sagittal sinus thrombosis due to L-asparaginase. ( 21042505 )
2010
34
Superior sagittal sinus thrombosis complicating neck dissection. ( 20298643 )
2010
35
A case of superior sagittal sinus thrombosis in pregnancy despite prophylactic antenatal heparin. ( 21126134 )
2010
36
Intracranial hypertension caused by a depressed skull fracture resulting in superior sagittal sinus thrombosis in a pediatric patient: treatment with ventriculoperitoneal shunt insertion. ( 20593983 )
2010
37
Susceptibility-weighted magnetic resonance imaging detects impaired cerebral hemodynamics in the superior sagittal sinus thrombosis--case report. ( 19556733 )
2009
38
Detection of superior sagittal sinus thrombosis on FDG PET. ( 19352280 )
2009
39
Anesthesia for cesarean delivery in the term pregnant following acute onset severe intracranial superior sagittal sinus thrombosis. ( 19961118 )
2009
40
Superior sagittal sinus thrombosis presenting as a continuous headache: a case report and review of the literature. ( 20062608 )
2009
41
Cortical blindness due to sagittal sinus thrombosis in acute lymphoblastic leukaemia. ( 19006563 )
2009
42
Hyperemesis gravidarum and first trimester sagittal sinus thrombosis. ( 18604696 )
2008
43
Superior sagittal sinus thrombosis: subtle signs on neuroimaging. ( 18536826 )
2008
44
[Sagittal sinus thrombosis as a rare cause of postpartum headache: a case report]. ( 18853684 )
2008
45
Bulky scalp metastasis and superior sagittal sinus thrombosis from a cervical adenocarcinoma: an unusual case. ( 18373834 )
2008
46
Protein S deficiency, epileptic seizures, sagittal sinus thrombosis and hemorrhagic infarction after ingestion of dimenhydrinate. ( 18382986 )
2008
47
Superior sagittal sinus thrombosis: a rare but serious complication of hypernatremic dehydration in newborns. ( 17313317 )
2007
48
Superior sagittal sinus thrombosis caused by calvarial tuberculosis: case report. ( 17415184 )
2007
49
Superior sagittal sinus thrombosis. ( 17711081 )
2007
50
Spontaneous superior sagittal sinus thrombosis secondary to type II heparin-induced thrombocytopenia presenting as an acute subarachnoid hemorrhage. ( 17582771 )
2007

Variations for Sagittal Sinus Thrombosis

Expression for Sagittal Sinus Thrombosis

Search GEO for disease gene expression data for Sagittal Sinus Thrombosis.

Pathways for Sagittal Sinus Thrombosis

GO Terms for Sagittal Sinus Thrombosis

Cellular components related to Sagittal Sinus Thrombosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.65 BLVRA CTSH F2 F3 SERPINC1
2 extracellular region GO:0005576 9.55 CTSH F2 F3 F5 SERPINC1
3 endoplasmic reticulum lumen GO:0005788 9.13 F2 F5 SERPINC1
4 extracellular space GO:0005615 9.02 CTSH F2 F3 F5 SERPINC1

Biological processes related to Sagittal Sinus Thrombosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 9.46 CTSH F2 F5 SERPINC1
2 activation of cysteine-type endopeptidase activity involved in apoptotic process GO:0006919 9.32 CTSH F3
3 regulation of blood coagulation GO:0030193 9.26 F2 SERPINC1
4 blood coagulation GO:0007596 9.26 F2 F3 F5 SERPINC1
5 hemostasis GO:0007599 8.92 F2 F3 F5 SERPINC1

Molecular functions related to Sagittal Sinus Thrombosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 serine-type endopeptidase activity GO:0004252 8.8 CTSH F2 F3

Sources for Sagittal Sinus Thrombosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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