MCID: SLV002
MIFTS: 48

Salivary Gland Cancer malady

Cancer category

Summaries for Salivary Gland Cancer

Sources:
34MedlinePlus, 64Wikipedia, 33MalaCards
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MedlinePlus:34 Your salivary glands make saliva - sometimes called spit - and empty it into your mouth through openings called ducts. saliva makes your food moist, which helps you chew and swallow. it helps you digest your food. it also cleans your mouth and contains antibodies that can kill germs. salivary gland cancer is a type of head and neck cancer. it is rare. it may not cause any symptoms, or you could notice a lump in your ear, cheek, jaw, lip, or inside the mouth fluid draining from your ear trouble swallowing or opening the mouth widely numbness, weakness, or pain in your face doctors diagnose salivary gland cancer using a physical exam, imaging tests, and a biopsy. treatment can include surgery, radiation therapy, and/or chemotherapy. nih: national cancer institute

MalaCards: Salivary Gland Cancer, also known as malignant neoplasm of salivary gland, is related to oral cancer and thyroid cancer. An important gene associated with Salivary Gland Cancer is MET (met proto-oncogene), and among its related pathways are Immune System and TGF-Beta Pathway. The compounds pge2 and egcg have been mentioned in the context of this disorder. Related mouse phenotypes are embryogenesis and endocrine/exocrine gland.

Wikipedia:64 Salivary gland cancer is a cancer that forms in tissues of a salivary gland. The salivary glands are... more...

Aliases & Classifications for Salivary Gland Cancer

Sources:
8Disease Ontology, 10DISEASES, 45Novoseek, 34MedlinePlus, 61UMLS, 27ICD9CM, 57SNOMED-CT, 35MeSH, 25ICD10
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer


Aliases & Descriptions:

salivary gland cancer 8 10 45 34
malignant neoplasm of salivary gland 8 61
malignant neoplasm of other major salivary glands 8
malignant neoplasm of salivary gland, unspecified 8
malignant neoplasm of major salivary gland, nos 8
malignant neoplasm of major salivary gland nos 8
malignant tumor of the major salivary gland 8
malignant neoplasm of major salivary gland 8
malignant neoplasm of salivary gland duct 8
malignant neoplasm of salivary gland nos 8
malignant tumor of major salivary gland 8
malignant tumor of the salivary gland 8
malignant tumor of salivary gland 8


External Ids:

Disease Ontology8 DOID:8850
ICD9CM27 142.8
SNOMED-CT57 187648003
MeSH35 D012468
ICD1025 C08

Related Diseases for Salivary Gland Cancer

Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases in the Salivary Gland Cancer family:

salivary gland cancer, adult

Diseases related to Salivary Gland Cancer via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 94)
idRelated DiseaseScoreTop Affiliating Genes
1oral cancer30.5BIRC5, NFKBIA
2thyroid cancer30.2PPARG, MET, CFLAR, SERPINB5
3salivary gland cancer, childhood10.4
4brooke-spiegler syndrome10.3
5salivary gland cancer, adult10.3
6parotid gland cancer10.1
7adenoid cystic carcinoma10.1
8mucoepidermoid carcinoma10.1
9acne10.1
10brain cancer10.1
11hypoxia10.1
12endometrial carcinoma10.0CFLAR
13gingivitis10.0MMP13
14endometriosis10.0HGF
15liver cirrhosis10.0HGF
16malignant mesothelioma10.0HGF, MET
17pituitary adenoma10.0PPARG
18hepatitis10.0HGF, CASP8
19laryngeal squamous cell carcinoma10.0BIRC5, MMP13
20ischemia10.0CFLAR, HGF
21medulloblastoma10.0CASP8, HGF
22myocardial infarction10.0MMP13
23gastrointestinal stromal tumor10.0KIT
24ectodermal dysplasia10.0NFKBIA, CHUK
25insulin resistance10.0NFKBIA, PPARG
26ataxia telangiectasia10.0CHUK
27fatty liver disease10.0PPARG
28bladder carcinoma10.0SERPINB5, CFLAR
29cholangiocarcinoma10.0CFLAR, MET, HGF
30myoepithelioma10.0MFSD1, SERPINB5
31myeloid leukemia10.0KIT, BIRC5, CASP8
32neurofibroma10.0KIT, MMP13, MET
33biliary tract cancer10.0MET
34osteoarthritis10.0NFKBIA, MMP13, CFLAR
35thyroid cancer, anaplastic10.0CASP8, PPARG, MET
36chondrosarcoma10.0MET, NFKBIA, MMP13
37acute leukemia10.0CASP8, BIRC5, KIT
38follicular adenoma10.0HGF, PPARG, MET, SERPINB5
39malignant peripheral nerve sheath tumor10.0KIT, MMP13, MET
40astrocytoma10.0CASP8, MET, NFKBIA, TSC22D1
41pleomorphic adenoma10.0PLAG1, MFSD1
42papillary carcinoma10.0SERPINB5, MET, PPARG, HGF
43papillary thyroid carcinoma10.0HGF, PPARG, MET, SERPINB5
44synovial sarcoma10.0KIT, MMP13, MET, HGF
45sarcoma10.0SERPINB5, CFLAR, KIT, MET
46skin cancer10.0CFLAR, CHUK, AKT3
47hepatitis b10.0CASP8, CHUK, NFKBIA
48hypohidrotic ectodermal dysplasia10.0NFKBIA, CHUK
49retinoblastoma10.0CASP8, PPARG, RB1CC1, BIRC5
50arthritis10.0CHUK, NFKBIA, MMP13, CFLAR

Graphical network of the top 20 diseases related to Salivary Gland Cancer:



Diseases related to salivary gland cancer

Clinical Features for Salivary Gland Cancer

Drugs & Therapeutics for Salivary Gland Cancer

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Salivary Gland Cancer

Drug clinical trials:

Search ClinicalTrials for Salivary Gland Cancer

Search NIH Clinical Center for Salivary Gland Cancer

Search CenterWatch for Salivary Gland Cancer

Genetic Tests for Salivary Gland Cancer

Anatomical Context for Salivary Gland Cancer

Animal Models for Salivary Gland Cancer or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
See all sources

Publications for Salivary Gland Cancer

Sources:
51PubMed
See all sources

Articles related to Salivary Gland Cancer:

(show top 50)    (show all 108)
idTitleAuthorsYear
1
Salivary gland cancer stem cells. (23810400)
2013
2
Aberrations of MET are associated with copy number gain of EGFR and loss of PTEN and predict poor outcome in patients with salivary gland cancer. (23242174)
2013
3
A randomized controlled trial for the use of Thymus Honey in decreasing Salivary Gland Damage following Radioiodine Therapy for Thyroid cancer: research protocol. (24256334)
2013
4
The Justy mutant mouse strain produces a spontaneous murine model of salivary gland cancer with myoepithelial and basal cell differentiation. (23608756)
2013
5
Expression and function of CXCR4 in human salivary gland cancers. (22847686)
2013
6
Predictors of cervical lymph node metastasis in salivary gland cancer. (23780687)
2013
7
Salivary gland cancer: an update on present and emerging therapies. (23714518)
2013
8
Predictive index for lymph node management of major salivary gland cancer. (22539053)
2012
9
Botulinum toxin A for oral cavity cancer patients: in microsurgical patients BTX injections in major salivary glands temporarily reduce salivary production and the risk of local complications related to saliva stagnation. (23202301)
2012
10
Loss of PTEN is associated with elevated EGFR and HER2 expression and worse prognosis in salivary gland cancer. (22240798)
2012
11
Cyclophosphamide, doxorubicin, and cisplatin in advanced salivary gland cancer. (21563549)
2011
12
A comprehensive analysis of parotid and salivary gland cancer: worse outcomes for male gender. (20189602)
2011
13
Matrix metalloproteinase (MMP)-7 in salivary gland cancer. (19929564)
2010
14
Treatment Results of Major Salivary Gland Cancer by Surgery with or without Postoperative Radiation Therapy. (20607079)
2010
15
Myoepithelial carcinoma of the salivary glands: a clinicopathologic study of 51 cases in a tertiary cancer center. (20644067)
2010
16
The oncogenic effects of constitutive Stat3 signaling in salivary gland cancer cells are mediated by survivin and modulated by the NSAID sulindac. (19272804)
2009
17
Role of Akt isoforms in HGF-induced invasive growth of human salivary gland cancer cells. (18355439)
2008
18
Quantitative promoter hypermethylation analysis of cancer-related genes in salivary gland carcinomas: comparison with methylation-specific PCR technique and clinical significance. (18451230)
2008
19
Late recurrence from salivary gland cancer: when does "cure" mean cure? (18008358)
2008
20
Matrix metalloproteinase (MMP)-1, -9 and -13 as prognostic factors in salivary gland cancer. (18368586)
2008
21
Prognostic value of immunohistochemistry in salivary gland cancer]. (18214402)
2008
22
Prognostic significance of EGFR, p53 and E-cadherin in mucoepidermoid cancer of the salivary glands: a retrospective case series. (17685120)
2007
23
Sustained expression of Mect1-Maml2 is essential for tumor cell growth in salivary gland cancers carrying the t(11;19) translocation. (16652146)
2006
24
Hypoxia enhances c-Met/HGF receptor expression and signaling by activating HIF-1alpha in human salivary gland cancer cells. (16469527)
2006
25
Insights into a complex group of neoplastic disease: advances in histopathologic classification and molecular pathology of salivary gland cancer. (16938808)
2006
26
Salivary gland cancer in Finland 1991--96: an evaluation of 237 cases. (15880955)
2005
27
An update on the systemic therapy of malignant salivary gland cancers: role of chemotherapy and molecular targeted agents. (15579019)
2004
28
Occupational exposures and salivary gland cancer mortality among African American and white workers in the United States. (15091292)
2004
29
Enhancement of apoptosis in salivary gland cancer cells by the combination of oral fluoropyrimidine anticancer agent (S-1) and radiation. (15375539)
2004
30
Expression of peroxisome proliferator-activated receptor gamma and the growth inhibitory effect of its synthetic ligands in human salivary gland cancer cell lines. (11836575)
2002
31
Vesnarinone, a differentiation inducing drug, directly activates p21(waf1) gene promoter via Sp1 sites in a human salivary gland cancer cell line. (12434298)
2002
32
Nodal metastasis in major salivary gland cancer: predictive factors and effects on survival. (12162768)
2002
33
Over-expression of TSC-22 (TGF-beta stimulated clone-22) markedly enhances 5-fluorouracil-induced apoptosis in a human salivary gland cancer cell line. (10879745)
2000
34
Menstrual and reproductive factors for salivary gland cancer risk in women. (10468426)
1999
35
Salivary gland cancer in the United States. (10613342)
1999
36
Exposure to nitrosamines and mortality from salivary gland cancer among rubber workers. (10535801)
1999
37
Induction of TSC-22 by treatment with a new anti-cancer drug, vesnarinone, in a human salivary gland cancer cell. (9459148)
1998
38
Detection of prostate specific antigen in pancreas and salivary glands: a potential impact on prostate cancer overestimation. (8683704)
1996
39
Prognostic factors in minor salivary gland cancer. (8847206)
1995
40
Recent trends in the incidence of salivary gland cancer. (1955246)
1991
41
Salivary gland cancer linked to past radiation for acne. (2143932)
1990
42
Observations on the natural history and treatment of recurrent major salivary gland cancer. (2370797)
1990
43
Salivary gland cancer. A case-control investigation of risk factors. (2206501)
1990
44
Salivary gland cancer and risk of subsequent skin cancer. (2358338)
1990
45
Second primary tumor associated with salivary gland cancer. (6589581)
1984
46
Chemotherapy for salivary gland cancer. (6279995)
1982
47
Screening for radiation-associated thyroid and salivary gland cancer. (723840)
1978
48
The association between salivary gland cancer and breast cancer. (5394367)
1969
49
The unique association between salivary gland cancer and breast cancer. (4296718)
1968
50
A roentgen study of skeletal and intrathoracic metastases from salivary gland cancer. (14786417)
1950

Genetic Variations for Salivary Gland Cancer

Expression for genes affiliated with Salivary Gland Cancer

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Salivary Gland Cancer

Search GEO for disease gene expression data for Salivary Gland Cancer.

Pathways for genes affiliated with Salivary Gland Cancer

Sources:
54Reactome, 52QIAGEN, 30KEGG, 38NCBI BioSystems Database, 12EMD Millipore, 60Tocris Bioscience, 53R&D Systems, 56SinoBiological, 4Cell Signaling Technology
See all sources

Pathways related to Salivary Gland Cancer according to GeneCards/GeneDecks:

(show top 50)    (show all 88)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.4HGF
2
Hide members
10.1HGF, MAP3K14
3
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10.0CASP8, BIRC2, CHUK
4
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10.0AKT3, NFKBIA, CHUK
59.9NFKBIA, BIRC2, CHUK
69.9CHUK, NFKBIA, MAP3K14
79.9MAP3K14, CHUK, NFKBIA
89.9BIRC2, NFKBIA, MAP3K14
99.8CHUK, CASP8, NFKBIA, MMP13
10
Hide members
9.8CHUK, AKT3, MET, NFKBIA
11
Hide members
9.8NFKBIA, MET, CHUK, MAP3K14
129.8NFKBIA, CHUK, AKT3, CASP8
13
Development PDGF signaling via STATs and NF-kB
Hide members
9.8CHUK, NFKBIA, AKT3, BIRC5
14
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9.8BIRC2, CFLAR, CASP8, CHUK
15
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9.8CASP8, CHUK, NFKBIA, BIRC2
16
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9.8CASP8, CHUK, NFKBIA, BIRC2
17
Hide members
9.8CHUK, AKT3, BIRC5, KIT
18
Apoptosis and survival Caspase cascade
Hide members
9.8BIRC2, CFLAR, AKT3, CASP8
199.7BIRC2, NFKBIA, CHUK, AKT3
209.7AKT3, MAP3K14, NFKBIA, CHUK
21
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9.7NFKBIA, CHUK, MMP13, HGF, RB1CC1
22
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9.7CHUK, NFKBIA, BIRC2, MAP3K14
23
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9.7BIRC2, CHUK, NFKBIA, MAP3K14
24
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9.7BIRC2, AKT3, NFKBIA, MAP3K14
25
Hide members
9.7HGF, NFKBIA, AKT3, MET, KIT
269.7KIT, CHUK, AKT3, HGF, MET
27
Hide members
9.7CHUK, MAP3K14, NFKBIA, HGF, MET
28
Hide members
9.7CHUK, AKT3, MET, CASP8, NFKBIA
29
Hide members
9.7CHUK, MET, CASP8, AKT3, NFKBIA
309.7BIRC5, SERPINB5, CASP8, BIRC2, CFLAR
319.6PPARG, NFKBIA, MAP3K14, AKT3, CHUK
32
Hide members
9.6NFKBIA, AKT3, BIRC2, CHUK, CASP8
33
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9.6MAP3K14, NFKBIA, CHUK, AKT3, BIRC5
34
Hide members
9.6CASP8, CHUK, BIRC2, MAP3K14, NFKBIA
35
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9.6CASP8, CHUK, NFKBIA, MAP3K14, BIRC2
36
Apoptosis and survival Anti-apoptotic TNFs/NF-kB/Bcl-2 pathway
Hide members
9.6CHUK, MAP3K14, BIRC5, BIRC2, NFKBIA
379.6NFKBIA, CHUK, MAP3K14, CFLAR, BIRC2
38
Apoptosis and survival Lymphotoxin-beta receptor signaling
Hide members
9.5NFKBIA, MAP3K14, BIRC2, CHUK, AKT3
399.5CRTC1, AKT3, MAP3K14, CHUK, NFKBIA
40
Hide members
9.5CASP8, AKT3, NFKBIA, CFLAR, CHUK, BIRC5
41
Hide members
9.4NFKBIA, CHUK, CFLAR, BIRC2, AKT3, CASP8
429.4CASP8, CFLAR, NFKBIA, BIRC2, CHUK, MAP3K14
43
Hide members
9.4NFKBIA, HGF, CASP8, CFLAR, MET, KIT
44
Hide members
9.4CASP8, MET, NFKBIA, HGF, KIT, AKT3
45
Hide members
9.4MET, BIRC2, NFKBIA, CHUK, HGF, AKT3
46
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9.3NFKBIA, CHUK, CFLAR, BIRC5, BIRC2, MAP3K14
47
Hide members
9.2CHUK, AKT3, CASP8, NFKBIA, MAP3K14, CFLAR
489.2CHUK, AKT3, CASP8, MAP3K14, NFKBIA, BIRC2
498.9BIRC2, HGF, CASP8, PPARG, MET, AKT3
50
Hide members
8.9PPARG, CASP8, AKT3, HGF, NFKBIA, BIRC2

Compounds for genes affiliated with Salivary Gland Cancer

Sources:
45Novoseek, 50PharmGKB, 11DrugBank, 60Tocris Bioscience, 29IUPHAR, 24HMDB
See all sources

Compounds related to Salivary Gland Cancer according to GeneCards/GeneDecks:

(show top 50)    (show all 114)
idCompoundScoreTop Affiliating Genes
1pge24510.5MET, BIRC5
2egcg4510.5CHUK, MAP3K14
3pdtc4510.4CHUK, SERPINB5, PPARG, MET
4cycloheximide4510.3BIRC2, TSC22D1, CASP8, HGF
5pga14510.2PPARG, CHUK, NFKBIA
6paclitaxel45 50 1112.1CASP8, NFKBIA, BIRC5, CFLAR, HGF
7suberoylanilide hydroxamic acid4510.1CASP8, PPARG, CFLAR, BIRC5, NFKBIA
8dutp4510.1NFKBIA, CFLAR, CASP8, BIRC5
9serine4510.1CHUK, AKT3, NFKBIA, MMP13, CFLAR
1015-deoxy-delta-12,14-prostaglandin j24510.0BIRC2, BIRC5, PPARG, NFKBIA, CASP8
11bortezomib45 1111.0CFLAR, NFKBIA, CHUK, CASP8, BIRC5
12thalidomide45 50 60 1113.0HGF, CHUK, NFKBIA, BIRC2, BIRC5
13p0024510.0MET, MMP13, BIRC5, KIT, SERPINB5, CFLAR
14aspirin45 50 29 2412.9BIRC5, NFKBIA, CHUK, PPARG, HGF, SERPINB5
15mg 13245 6010.9NFKBIA, CASP8, CFLAR, HGF, BIRC5
16retinoid459.9NFKBIA, PPARG, HGF, MMP13, CASP8, CHUK
17docetaxel45 50 60 1112.9CASP8, BIRC2, CFLAR, BIRC5, KIT
18n acetylcysteine459.9NFKBIA, PPARG, CHUK, CASP8, HGF, BIRC5
19geldanamycin45 50 60 1112.8CFLAR, BIRC5, NFKBIA, CHUK, MET, KIT
20arsenite45 2410.8BIRC2, CFLAR, BIRC5, CASP8, CHUK, NFKBIA
21etoposide45 50 60 1112.8CFLAR, BIRC2, NFKBIA, CASP8, HGF, BIRC5
22imatinib45 50 1111.8HGF, CASP8, KIT, CFLAR, BIRC5
23adriamycin459.8MET, CASP8, HGF, CFLAR, NFKBIA, BIRC2
24sb 20358045 6010.8BIRC5, HGF, CASP8, PPARG, NFKBIA, MMP13
25curcumin459.8BIRC2, PPARG, CASP8, CHUK, NFKBIA, MMP13
26rapamycin459.8PPARG, CHUK, NFKBIA, BIRC5, KIT, MET
27sp 60012545 6010.7MAP3K14, CASP8, HGF, MMP13, BIRC2, NFKBIA
28flavopiridol45 1110.7CFLAR, KIT, BIRC5, CASP8
29dexamethasone45 50 29 1112.7BIRC2, CHUK, CASP8, HGF, MMP13, NFKBIA
30testosterone45 60 11 2412.7PPARG, HGF, MET, NFKBIA, SERPINB5, CFLAR
31nitric oxide45 11 2411.5MET, CHUK, NFKBIA, BIRC5, KIT, CFLAR
32cisplatin45 50 60 1112.5BIRC2, NFKBIA, CHUK, MET, CASP8, CFLAR
33actinomycin d459.5BIRC5, NFKBIA, MMP13, BIRC2, MET, CFLAR
34alanine459.5HGF, MAP3K14, CASP8, PPARG, BIRC5, MET
35doxorubicin45 50 1111.5HGF, CASP8, CFLAR, CHUK, NFKBIA, BIRC2
36wortmannin459.4MET, HGF, CASP8, BIRC5, NFKBIA, BIRC2
375fluorouracil459.4CFLAR, BIRC5, NFKBIA, CHUK, KIT, HGF
38h2o2459.4CFLAR, HGF, CASP8, CHUK, NFKBIA, MAP3K14
39retinoic acid45 2410.4PPARG, CASP8, HGF, CHUK, NFKBIA, MMP13
40threonine459.4MAP3K14, CFLAR, KIT, BIRC5, MET, NFKBIA
41pd 98,059459.3MET, HGF, CHUK, KIT, CASP8, CFLAR
42oligonucleotide459.3MET, PLAG1, KIT, CFLAR, NFKBIA, CHUK
43paraffin459.3MMP13, SERPINB5, KIT, BIRC5, MET, HGF
44lipid459.3SERPINB5, BIRC5, NFKBIA, CHUK, AKT3, MET
45oxygen45 2410.3CASP8, CFLAR, BIRC5, NFKBIA, CHUK, MET
46cysteine459.2CASP8, MET, CHUK, NFKBIA, CD151, MMP13
47vegf459.2NFKBIA, CFLAR, BIRC5, BIRC2, MMP13, CHUK
48ly294002459.2NFKBIA, BIRC2, CASP8, PPARG, MET, AKT3
49phosphatidylinositol459.1MMP13, NFKBIA, AKT3, MET, CASP8, HGF
50tyrosine459.0KIT, HGF, CASP8, MET, CHUK, NFKBIA

GO Terms for genes affiliated with Salivary Gland Cancer

Sources:
16Gene Ontology
See all sources

Cellular components related to Salivary Gland Cancer according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1CD40 receptor complexGO:03563110.1BIRC2, CHUK
2death-inducing signaling complexGO:03126410.1CASP8, CFLAR
3cytosolGO:0058298.9CFLAR, CASP8, PPARG, RB1CC1, CHUK, NFKBIA
4cytoplasmGO:0057378.2CASP8, CRTC1, AKT3, CHUK, NFKBIA, MAP3K14
5nucleusGO:0056348.1AKT3, RB1CC1, CRTC1, PPARG, CASP8, CHUK

Biological processes related to Salivary Gland Cancer according to GeneCards/GeneDecks:

(show all 20)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of hydrogen peroxide-mediated programmed cell deathGO:190129910.5MET, HGF
2myoblast proliferationGO:05145010.5MET, HGF
3regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signalingGO:06066510.4MET, HGF
4placenta developmentGO:00189010.3PPARG, MET, BIRC2
5regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.2CASP8, CFLAR
6NIK/NF-kappaB cascadeGO:03806110.2MAP3K14, BIRC2
7liver developmentGO:00188910.2RB1CC1, MET, HGF
8TRIF-dependent toll-like receptor signaling pathwayGO:03566610.1BIRC2, NFKBIA, CHUK, CASP8
9MyD88-independent toll-like receptor signaling pathwayGO:00275610.1CASP8, CHUK, NFKBIA, BIRC2
10toll-like receptor 3 signaling pathwayGO:03413810.1BIRC2, NFKBIA, CHUK, CASP8
11negative regulation of macrophage derived foam cell differentiationGO:01074510.1PPARG, NFKBIA
12toll-like receptor 4 signaling pathwayGO:03414210.1CASP8, CHUK, NFKBIA, BIRC2
13toll-like receptor signaling pathwayGO:00222410.1BIRC2, NFKBIA, CHUK, CASP8
14activation of MAPK activityGO:00018710.1KIT, MET, HGF
15regulation of cell proliferationGO:0421279.9KIT, BIRC2, NFKBIA
16positive regulation of I-kappaB kinase/NF-kappaB cascadeGO:0431239.9CASP8, CHUK, MAP3K14, BIRC2, CFLAR
17positive regulation of transcription from RNA polymerase II promoterGO:0459449.7HGF, PPARG, CRTC1, MET, CHUK, NFKBIA
18innate immune responseGO:0450879.7CASP8, PPARG, CHUK, NFKBIA, BIRC2, KIT
19negative regulation of apoptotic processGO:0430669.7TSC22D1, CFLAR, BIRC5, BIRC2, NFKBIA, RB1CC1
20apoptotic processGO:0069159.3CFLAR, BIRC5, BIRC2, NFKBIA, CASP8

Molecular functions related to Salivary Gland Cancer according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protease bindingGO:00202010.0CASP8, KIT, CFLAR
2protein bindingGO:0055157.4HGF, NFKBIA, CHUK, AKT3, RB1CC1, MET

Products for genes affiliated with Salivary Gland Cancer

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Salivary Gland Cancer

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet