Sarcoidosis 1 malady
Genetic diseases, Rare diseases, Immune diseases, Neuronal diseases, Eye diseases, Nephrological diseases, Respiratory diseases, Bone diseases, Endocrine diseases categories
Sarcoidosis 1, Aliases & Descriptions:
Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases, Rare diseases
Anatomical: Immune diseases, Neuronal diseases, Eye diseases, Nephrological diseases, Respiratory diseases, Bone diseases, Endocrine diseases
ICD10: 26 25
Rare neurological diseases
Rare eye diseases
Rare renal diseases
Rare respiratory diseases
Rare systemic and rhumatological diseases
Rare endocrine diseases
Characteristics (Orphanet epidemiological data):47
Inheritance: Multigenic/multifactorial; Prevalence: 1-5/10000 (Worldwide),1-5/10000 (Europe); Age of onset: Adult
OMIM:45 Sarcoidosis is a granulomatous disorder associated with an accumulation of CD4+ T cells and a Th1 immune response. In... (181000) more...
MalaCards based summary: Sarcoidosis 1, also known as sarcoidosis, is related to cardiac sarcoidosis and tuberculosis, and has symptoms including abnormality of the mouth, glaucoma and photophobia. An important gene associated with Sarcoidosis 1 is HLA-DRB1 (major histocompatibility complex, class II, DR beta 1). The drugs carmustine and cyclophosphamide have been mentioned in the context of this disorder. Affiliated tissues include lymph node, lung and skin.
Disease Ontology:9 A hypersensitivity reaction type iv disease characterized by the growth of collections of inflammatory cells (granulomas) in multiple organs.
NIH Rare Diseases:41 Sarcoidosis is an inflammatory disease characterized by the development and growth of tiny lumps of cells called granulomas. if these tiny granulomas grow and clump together in an organ, they can affect how the organ works, leading to the symptoms of sarcoidosis. the granulomas can be found in almost any part of the body, but occur more commonly in the lungs, lymph nodes, eyes, skin, and liver. although no one is sure what causes sarcoidosis, it is thought by most scientists to be a disorder of the immune system. the course of the disease varies from person to person. it often goes away on its own, but in some people symptoms of sarcoidosis may last a lifetime. for those who need treatment, anti-inflammatory medications can help. last updated: 3/30/2010
MedlinePlus:32 Sarcoidosis is a disease that leads to inflammation, usually in your lungs, skin, or lymph nodes. it starts as tiny, grain-like lumps, called granulomas. sarcoidosis can affect any organ in your body. no one is sure what causes sarcoidosis. it affects men and women of all ages and races. it occurs mostly in people ages 20 to 50, african americans, especially women, and people of northern european origin. many people have no symptoms. if you have symptoms, they may include cough shortness of breath weight loss night sweats fatigue tests to diagnose sarcoidosis include chest x-rays, lung function tests, and a biopsy. not everyone who has the disease needs treatment. if you do, prednisone, a type of steroid, is the main treatment. nih: national heart, lung, and blood institute
HPO human phenotypes related to Sarcoidosis 1:(show all 24)
Drug clinical trials:
Inferred drug relations via UMLS60/NDF-RT39:
MalaCards organs/tissues related to Sarcoidosis 1:31
Lymph node, Lung, Skin, Eye, Testes, Heart, Liver, T cells, Bone
Articles related to Sarcoidosis 1:
Search GEO for disease gene expression data for Sarcoidosis 1.
26ICD10 via Orphanet
34MESH via Orphanet
46OMIM via Orphanet
56SNOMED-CT via Orphanet
61UMLS via Orphanet