Sarcoidosis, Susceptibility L, 1 malady

MalaCards: Sarcoidosis, Susceptibility L, 1, also known as sarcoidosis, is related to pulmonary sarcoidosis and tuberculosis. An important gene associated with Sarcoidosis, Susceptibility L, 1 is HLA-DRB1 (major histocompatibility complex, class II, DR beta 1).

OMIM: 181000

sarcoidosis, susceptibility l, 1 33 sarcoidosis 43

Diseases related to sarcoidosis, susceptibility l, 1 by text searches and GeneDecks gene sharing:

(show top 50)    (show all 73)

id	Related Disease	Score	Top Affiliating Genes
1	pulmonary sarcoidosis	11.0
2	tuberculosis	8.6
3	fibrosis	8.4
4	pulmonary fibrosis	8.2
5	blau syndrome	8.1
6	idiopathic pulmonary fibrosis	8.1
7	cardiac sarcoidosis	7.9
8	asthma	7.7
9	hepatitis	7.7
10	hepatitis c	7.5
11	bronchial asthma	6.9
12	cerebral sarcoidosis	6.9
13	neurosarcoidosis	6.9
14	skin sarcoidosis	6.9
15	lung cancer	6.2
16	melkersson-rosenthal syndrome	6.2
17	pulmonary disease	6.2
18	pneumonia	6.2
19	pars planitis	6.2
20	hypercalcemic sarcoidosis	6.2
21	sarcoidosis 2	5.7
22	sarcoidosis 3	5.7
23	usual interstitial pneumonia	5.7
24	crohn's disease	5.7
25	extrinsic allergic alveolitis	5.7
26	hypercalcemia	5.7
27	hypertension	5.7
28	hypothyroidism	5.7
29	intermediate uveitis	5.7
30	lupus erythematosus	5.7
31	pulmonary hypertension	5.7
32	retinal vasculitis	5.7
33	retinitis	5.7
34	exophthalmos	4.8
35	necrobiosis lipoidica	4.8
36	vasculitis	4.8
37	granuloma annulare	4.8
38	non-hodgkin lymphoma	4.8
39	hodgkin's lymphoma	4.8
40	histiocytosis	4.8
41	pilomatrixoma	4.8
42	histoplasmosis	4.8
43	pulmonary function	4.8
44	acquired immunodeficiency syndrome	4.8
45	hypoglycemia	4.8
46	pneumothorax	4.8
47	addison's disease	4.8
48	hypoalphalipoproteinemia	4.8
49	progressive multifocal leukoencephalopathy	4.8
50	antisynthetase syndrome	4.8

Clinical features from OMIM: 181000

Approved drugs:

Drug clinical trials:

Genes related to sarcoidosis, susceptibility l, 1 according to GeneCards:

id	Symbol	Description	Score	GeneCards Section Context
1	HLA-DRB1	major histocompatibility complex, class II, DR beta 1	11.0	Disorders