MCID: SCH014
MIFTS: 58

Schistosomiasis malady

Categories: Rare diseases, Infectious diseases, Blood diseases

Aliases & Classifications for Schistosomiasis

Summaries for Schistosomiasis

NIH Rare Diseases : 50 schistosomiasis is a disease caused by parasitic worms. although the worms that cause schistosomiasis are not found in the united states, more than 200 million people are infected worldwide. infection occurs through contact with contaminated water. the parasite in its infective stages is called a cercaria. it swims freely in open bodies of water. on contact with humans, the parasite burrows into the skin, matures into another stage (schistosomula), then migrates to the lungs and liver, where it matures into the adult form. the adult worm then migrates to its preferred body part (bladder, rectum, intestines, liver, portal venous system (the veins that carry blood from the intestines to liver, spleen, lungs), depending on its species.  schistosomiasis is common in many tropical and subtropical areas worldwide. it can be treated safely and effectively with praziquantel. last updated: 3/15/2013

MalaCards based summary : Schistosomiasis, also known as katayama fever, is related to hepatitis and abdominal tuberculosis. An important gene associated with Schistosomiasis is IL4 (Interleukin 4), and among its related pathways/superpathways are Innate Immune System and PEDF Induced Signaling. The drugs Albendazole and Artemether have been mentioned in the context of this disorder. Affiliated tissues include liver, skin and spleen, and related phenotypes are homeostasis/metabolism and hematopoietic system

Disease Ontology : 12 A parasitic helminthiasis infectious disease that involves infection of the intestine, urinary tract, skin, liver and spleen caused by multiple species of the trematode fluke of the genus Schistosoma. The symptoms include fever, chills, nausea, abdominal pain, diarrhea, malaise, myalgia, liver and spleen enlargement, rash and hematuria.

CDC : 3 Schistosomiasis, also known as bilharzia, is a disease caused by parasitic worms. Although the worms that cause schistosomiasis are not found in the United States, more than 200 million people are infected worldwide. In terms of impact this disease is second only to malaria as the most devastating parasitic disease. Schistosomiasis is considered one of the Neglected Tropical Diseases (NTDs).

Wikipedia : 71 Schistosomiasis, also known as snail fever and bilharzia, is a disease caused by parasitic flatworms... more...

Related Diseases for Schistosomiasis

Diseases related to Schistosomiasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 469)
id Related Disease Score Top Affiliating Genes
1 hepatitis 30.3 IFNG IL10 IL2 TNF
2 abdominal tuberculosis 29.5 CD40LG CD79A IL10
3 loiasis 29.4 CD79A IFNG IL10 IL13 IL4 IL5
4 tuberculosis 29.4 CD40LG IL10 IL2 IL4 TNF
5 chronic thromboembolic pulmonary hypertension 29.2 IFNG IL10 IL2
6 pulmonary tuberculosis 28.8 CD40LG IFNG IGHE IL10 IL13 IL4
7 intestinal schistosomiasis 12.4
8 urinary schistosomiasis 12.3
9 cercarial dermatitis 11.8
10 schistosoma mansoni infection, susceptibility/ 11.3
11 neuroschistosomiasis 10.9
12 myoglobinuria recurrent 10.4 IFNG IL4
13 esophageal cancer, childhood 10.4 CD40LG IGHE
14 dahlberg borer newcomer syndrome 10.3 IL13 IL5
15 lymphoblastic leukemia 10.3 IL13 IL4 IL5
16 lactose intolerance 10.3 IL13 IL4 IL5
17 renal hypertension 10.3 IL13 IL5 RNASE3
18 lymphocytic gastritis 10.3 IL13 IL4 IL5
19 papillary squamous carcinoma 10.3 IGHE IL4 IL5
20 marasmus 10.3 IL4 IL5 RNASE3
21 duodenal somatostatinoma 10.3 IL13 IL4 IL5
22 alcoholic neuropathy 10.3 CD40LG CD79A
23 lens-induced iridocyclitis 10.3 IL4 IL5 RNASE3
24 camptodactyly vertebral fusion 10.3 CD40LG CD79A
25 israeli tick typhus 10.3 CD40LG IFNG IL13
26 cutaneous fibrous histiocytoma 10.3 IFNG IL4 IL5
27 pyridoxal 5'-phosphate-dependent epilepsy 10.3 IL10 TNF
28 cerebral primitive neuroectodermal tumor 10.3 IL4 IL5 RNASE3
29 disordered steroidogenesis due to cytochrome p450 oxidoreductase 10.3 IL13 IL5 STAT6
30 aortic atherosclerosis 10.3 IL13 IL5 TNF
31 asymptomatic neurosyphilis 10.3 IFNG IL10 IL4
32 childhood malignant mesenchymoma 10.3 IL13 IL5 RNASE3
33 hyperinsulinism due to glutamodehydrogenase deficiency 10.3 IFNG IGHE IL4
34 tungiasis 10.3 IFNG IL10 IL4
35 central gyrate choroidal dystrophy 10.3 CD40LG IGHE RNASE3
36 maturity-onset diabetes of the young 10.3 CD40LG IL10
37 stocco dos santos syndrome 10.3 IFNG IGHE TNF
38 multiple mitochondrial dysfunctions syndrome 10.3 IFNG IL10 IL5
39 hypotrichosis 4 10.3 IFNG IL4 TNF
40 spinal polio 10.3 CD40LG CD79A
41 tubular renal disease-cardiomyopathy syndrome 10.3 IL10 IL4 TNF
42 rabies 10.3 CD40LG CD79A
43 unilateral retinoblastoma 10.3 CD40LG CD79A
44 congenital dyserythropoietic anemia 10.3 ALB TNF
45 mesangial proliferative glomerulonephritis 10.3 CD40LG CD79A
46 lagophthalmos 10.3 IL10 IL4 TNF
47 tarsal tunnel syndrome 10.3 IL10 IL13 TNF
48 conidiobolomycosis 10.3 IL10 IL4 TNF
49 bile duct signet ring cell carcinoma 10.3 IL5 RNASE3 TNF
50 indomethacin antenatal infection 10.3 CD40LG CD79A IGHE

Graphical network of the top 20 diseases related to Schistosomiasis:



Diseases related to Schistosomiasis

Symptoms & Phenotypes for Schistosomiasis

MGI Mouse Phenotypes related to Schistosomiasis:

44 (show all 13)
id Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.36 TNF ALB ARG1 CD40LG CD79A F2
2 hematopoietic system MP:0005397 10.32 ARG1 CD40LG CD79A F2 IFNG IFNGR1
3 cellular MP:0005384 10.3 ALB CD40LG CD79A IFNG IFNGR1 IL10
4 immune system MP:0005387 10.28 TNF ARG1 CD40LG CD79A F2 IFNG
5 digestive/alimentary MP:0005381 10.21 ALB F2 IFNG IFNGR1 IL10 IL13
6 endocrine/exocrine gland MP:0005379 10.19 ALB CD40LG IFNG IFNGR1 IL10 IL13
7 liver/biliary system MP:0005370 10.15 ALB ARG1 CD79A IFNG IFNGR1 IL10
8 integument MP:0010771 10.06 CD40LG F2 IFNG IFNGR1 IL10 IL13
9 neoplasm MP:0002006 9.97 IL5 STAT6 TNF ALB CD79A IFNG
10 reproductive system MP:0005389 9.9 CD40LG F2 IFNG IFNGR1 IL10 IL13
11 renal/urinary system MP:0005367 9.86 CD79A IFNG IFNGR1 IL4 LGMN STAT6
12 respiratory system MP:0005388 9.61 IL2 IL4 IL5 STAT6 TNF F2
13 skeleton MP:0005390 9.28 CD40LG F2 IFNG IFNGR1 IL10 IL13

Drugs & Therapeutics for Schistosomiasis

Drugs for Schistosomiasis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 76)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Albendazole Approved, Vet_approved Phase 4,Phase 3 54965-21-8 2082
2
Artemether Approved Phase 4 71963-77-4 119380 68911
3
Lumefantrine Approved Phase 4 82186-77-4 6437380
4
Miconazole Approved, Investigational, Vet_approved Phase 4 22916-47-8 4189
5
Praziquantel Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 55268-74-1 4891
6 Anthelmintics Phase 4,Phase 3,Phase 2,Phase 1
7 Antifungal Agents Phase 4
8 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1
9 Antimalarials Phase 4,Phase 2,Phase 3
10 Antimitotic Agents Phase 4,Phase 3
11 Antiparasitic Agents Phase 4,Phase 3,Phase 2,Phase 1
12 Antiprotozoal Agents Phase 4,Phase 2,Phase 3
13 Artemether-lumefantrine combination Phase 4
14 Artemisinine Phase 4,Phase 2,Phase 3
15 Artemisinins Phase 4,Phase 2,Phase 3
16
Artesunate Approved Phase 2, Phase 3 88495-63-0 6917864 5464098
17
Pyrimethamine Approved, Vet_approved Phase 2, Phase 3 58-14-0 4993
18
Sulfadoxine Approved Phase 3,Phase 2 2447-57-6 17134
19
Iron Approved Phase 3 7439-89-6 23925
20
Tranexamic Acid Approved Phase 3 1197-18-8 5526
21
Myrrh Approved, Nutraceutical Phase 3 9000-45-7
22
Folic Acid Approved, Nutraceutical, Vet_approved Phase 2, Phase 3 59-30-3 6037
23
leucovorin Approved, Nutraceutical Phase 2, Phase 3 58-05-9 54575, 6560146 143
24 Micronutrients Phase 3
25 Trace Elements Phase 3
26 Vitamins Phase 3
27 Vaccines Phase 3,Phase 2,Phase 1
28 Folic Acid Antagonists Phase 2, Phase 3
29 Renal Agents Phase 2, Phase 3
30 Sulfalene Phase 2, Phase 3
31 Vitamin B Complex Phase 2, Phase 3
32 Fanasil, pyrimethamine drug combination Phase 3,Phase 2
33
Piperaquine Phase 3 4085-31-8 5079497
34 Triclabendazole Phase 3
35 Antifibrinolytic Agents Phase 3
36 Coagulants Phase 3
37 Hemostatics Phase 3
38 Ferric Compounds Phase 3
39 Hematinics Phase 3
40 Folate Nutraceutical Phase 2, Phase 3
41 Vitamin B9 Nutraceutical Phase 2, Phase 3
42 Iron Supplement Nutraceutical Phase 3
43
Mefloquine Approved Phase 2 53230-10-7 4046
44 Pharmaceutical Solutions Phase 2
45
Aluminum hydroxide Approved Phase 1 21645-51-2
46 Adjuvants, Immunologic Phase 1
47 Aluminum sulfate Phase 1
48 Antacids Phase 1
49 Antibodies Phase 1
50 Anti-Ulcer Agents Phase 1

Interventional clinical trials:

(show top 50) (show all 61)
id Name Status NCT ID Phase
1 Artemisinin-based Combination Therapy-Intermittent Preventive Treatment (ACT-IPT) Trial Among Schoolchildren in Kassena-Nankana, Ghana Unknown status NCT01459146 Phase 4
2 Effect of Schistosomiasis Mansoni on HIV Susceptibility and Female Genital Immunology Completed NCT02878564 Phase 4
3 Evaluation of Praziquantel Dosage for Treatment of Schistosomiasis in Brazil Completed NCT00403611 Phase 4
4 A Multinational Trial of the Efficacy of Albendazole Against Soil-transmitted Nematode Infections in Children Completed NCT01087099 Phase 4
5 Repeated Doses of Praziquantel in Schistosomiasis Treatment (RePST) Not yet recruiting NCT02868385 Phase 4
6 Effect of Concomitant Mansonella Perstans Microfilaremia on Immune Responses Following Single Dose Praziquantel in People With Schistosomiasis Not yet recruiting NCT02734186 Phase 4
7 Safety and Efficacy of Mirazid for Schistosomiasis Treatment Completed NCT01529710 Phase 3
8 Efficacy of Bilhvax in Association With Praziquantel for Prevention of Clinical Recurrences of Schistosoma Haematobium Completed NCT00870649 Phase 3
9 Schistosoma Haematobium Infections and Praziquantel Completed NCT01558336 Phase 3
10 Comparing Praziquantel Versus Artesunate + Sulfamethoxypyrazine/Pyrimethamine for Treating Schistosomiasis Completed NCT00510159 Phase 2, Phase 3
11 Impact IPT With Sulfadoxine-pyrimethamine or Sulfadoxine-pyrimethamine Plus Piperaquine in Schoolchildren Completed NCT01722539 Phase 3
12 The Chinese-made Praziquantel for Treatment of Schistosoma Haematobium Recruiting NCT03133832 Phase 3
13 Haemorrhage Alleviation With Tranexamic Acid- Intestinal System Recruiting NCT01658124 Phase 3
14 IV Ferric Carboxymaltose Compared With Oral Iron in the Treatment of Iron Deficiency Anemia at Delivery in Tanzania Active, not recruiting NCT02541708 Phase 3
15 Activity of Mefloquine Against Urinary Schistosomiasis Completed NCT01132248 Phase 2
16 Schistosoma Mansoni Morbidity in Children Aged 1-5 Years Completed NCT01901484 Phase 2
17 S. Japonicum and Pregnancy Outcomes Completed NCT00486863 Phase 2
18 Trial to Investigate the Effect of Schistosoma Mansoni Infection on the Response to Vaccination With MVA85A in BCG-vaccinated African Adolescents Completed NCT02178748 Phase 2
19 An Open Label Dose Finding Safety and Efficacy in Children and Infants Infected With Schistosomiasis (S.Mansoni) Recruiting NCT02806232 Phase 2
20 Study of Safety and Immune Response of the Sm14 Vaccine in Adults of Endemic Regions Active, not recruiting NCT03041766 Phase 2
21 Study to Evaluate the Safety of the Vaccine Prepared sm14 Against Schistosomiasis Completed NCT01154049 Phase 1
22 Clinical Trial of Bilhvax,a Vaccine Candidate Against Schistosomiasis Completed NCT01512277 Phase 1
23 Praziquantel-Pharmacokinetic Study Completed NCT01288872 Phase 1
24 Safety and Immunogenicity Study of a DNA Vaccine Combined With Protein Vaccine Against HIV/AIDS Completed NCT02376582 Phase 1
25 A Phase I Study of the Safety, Reactogenicity, and Immunogenicity of Sm-TSP-2/Alhydrogel® With or Without GLA-AF for Intestinal Schistosomiasis in Healthy Adults Active, not recruiting NCT02337855 Phase 1
26 A Phase Ib Trial to Evaluate the Safety, Reactogenicity, and Immunogenicity of Sm-TSP-2/Alhydrogel® With or Without GLA-AF for Intestinal Schistosomiasis in Healthy Exposed Adults Not yet recruiting NCT03110757 Phase 1
27 Evaluation of Strategies for Improved Uptake of Preventive Treatment for Intestinal Schistosomiasis Unknown status NCT01869465
28 Antioxidant Supplements in the Reversal of Schistosomal Peri-portal Fibrosis Unknown status NCT01260012
29 A Study of Co-infections of HIV-1 and Schistosoma Mansoni and Its Impact on Praziquantel Treatment Outcomes Unknown status NCT01541631
30 Health Benefits of Repeated Treatment in Pediatric Schistosomiasis Completed NCT01424410
31 Women and Children as the Focus for Control of Schistosomiasis Infections in the Irrigations Area of Burkina Faso Completed NCT00463528
32 Arachidonic Acid Treatment Against Schistosomiasis Infection in Children Completed NCT02144389
33 Urinary Schistosomiasis Infection Completed NCT00138450
34 Assessment of Anaemia Attributable to Schistosomiasis in School Children in Kenya: Mechanisms and Effect of Treatment Completed NCT00414479
35 Schistosomiasis in Women of Reproductive Age in Burkina Faso: Implications for Control Completed NCT00463632
36 Iron Supplementation in Schistosomiasis and Soil Transmitted Helminths Control Programmes in Zambia Completed NCT00276224
37 Schistosomiasis in Formal and Non-Formal Schools in Uganda: Implications for Control Programmes Completed NCT00463593
38 Using Community-Based Volunteers to Reach Non-Enrolled School Aged Children Through Community-Directed Treatment of Schistosomiasis in School-Aged Children in Rural Northern Ghana Completed NCT00463931
39 Evaluation of the Use of a Urin Test Strip to Determine the Spread of Schistosoma Infections in Areas Where Schistosomiasis Infections Are Low in Kenya Completed NCT00463307
40 Urogenital Schistosomiasis and Sexually Transmitted Infections in Madagascar Completed NCT00713999
41 Schistosomiasis Effect on Response to Vaccines, Anaemia and Nutritional Status of Children of Northern Senegal Completed NCT01553552
42 Treatment Schistosomal Portal Hypertension: Efficacy of Endoscopy or Surgery Completed NCT01931826
43 The Effect of Praziquantel Treatment on Schistosoma Mansoni Morbidity and re-Infection Along Lake Victoria, Uganda Completed NCT00215267
44 Safety and Efficacy of Drug Combinations Against Schistosomiasis Completed NCT01050374
45 Worm Infestation and Child Health in Zimbabwe Completed NCT01283165
46 Correlating Protection Against Malaria With Serum Profiles Against Plasmodium Falciparum Antigen Repertoires Completed NCT01214876
47 Pulmonary Hypertension in Patients With Sickle Cell Disease in Nigeria Completed NCT00367523
48 Safety and Efficacy of Drug Combinations Against Triple Infections Completed NCT01050517
49 Community Directed Treatment of Soil-Transmitted Helminths Among Young Children in Zambia Completed NCT00349323
50 Schistosome and Intestinal Worm Infections and Malaria Morbidity Among School and Pre-school Children in, Tanzania Completed NCT00347113

Search NIH Clinical Center for Schistosomiasis

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Genetic Tests for Schistosomiasis

Anatomical Context for Schistosomiasis

MalaCards organs/tissues related to Schistosomiasis:

39
Liver, Skin, Spleen, Kidney, Testes, Lung, Colon

Publications for Schistosomiasis

Articles related to Schistosomiasis:

(show top 50) (show all 1303)
id Title Authors Year
1
New index for the diagnosis of liver fibrosis in Schistosomiasis mansoni. ( 28079240 )
2017
2
Towards interruption of schistosomiasis transmission in sub-Saharan Africa: developing an appropriate environmental surveillance framework to guide and to support 'end game' interventions. ( 28088239 )
2017
3
Indicators of improved water access in the context of schistosomiasis transmission in rural Eastern Region, Ghana. ( 27939198 )
2017
4
A new global strategy for the elimination of schistosomiasis. ( 27939558 )
2017
5
Exploring possibilities for an alternative approach in experimental schistosomiasis mansoni: the peritoneal cavity of mice. ( 28030359 )
2017
6
Recent advances in proteomic applications for schistosomiasis research: potential clinical impact. ( 27937063 )
2017
7
Urogenital schistosomiasis during pregnancy is associated with low birth weight delivery: analysis of a prospective cohort of pregnant women and their offspring in Gabon. ( 28003151 )
2017
8
Cerebral schistosomiasis: diffusion-weighted imaging helps to differentiate from brain glioma and metastasis. ( 28090792 )
2017
9
Estrogen catechols detection as biomarkers in schistosomiasis induced cancer and infertility. ( 28018158 )
2017
10
Schistosomiasis and Soil Transmitted Helminths Distribution in Benin: A Baseline Prevalence Survey in 30 Districts. ( 27643795 )
2016
11
Human Schistosomiasis mansoni associated with hepatocellular carcinoma in Egypt: current perspective. ( 27605822 )
2016
12
POTENTIAL CONTRIBUTION OF ADULT POPULATIONS TO THE MAINTENANCE OF SCHISTOSOMIASIS AND SOIL-TRANSMITTED HELMINTH INFECTIONS IN THE SIAVONGA AND MAZABUKA DISTRICTS OF ZAMBIA. ( 27180827 )
2016
13
Magnetic Resonance Spectroscopy for Evaluating Portal-Systemic Encephalopathy in Patients with Chronic Hepatic Schistosomiasis Japonicum. ( 27977668 )
2016
14
Evaluation of schistosomiasis control activities in the Family Health Strategy in municipalities in the Jequitinhonha Valley, Minas Gerais, Brazil. ( 27532760 )
2016
15
Saposin-like Proteins, a Multigene Family of Schistosoma Species, Are Biomarkers for the Immunodiagnosis of Schistosomiasis Japonica. ( 27190177 )
2016
16
Intestinal Schistosomiasis among Primary Schoolchildren in Two On-Shore Communities in Rorya District, Northwestern Tanzania: Prevalence, Intensity of Infection and Associated Risk Factors. ( 27822385 )
2016
17
Significance of Echogenic Snow Sign as an Ultrasonography Finding for Diagnosis of Urogenital Schistosomiasis. ( 27549638 )
2016
18
Circulating cathodic antigen cassette test versus haematuria strip test in diagnosis of urinary schistosomiasis. ( 27876913 )
2016
19
Policy Support and Resources Mobilization for the National Schistosomiasis Control Programme in The People's Republic of China. ( 27137452 )
2016
20
Improving the understanding of schistosomiasis among adolescents in endemic areas in Brazil: A comparison of educational methods. ( 27180618 )
2016
21
Smallpox and Dracunculiasis: The Scientific Value of Infectious Diseases That Have Been Eradicated or Targeted for Eradication. Is Schistosomiasis Next? ( 26741130 )
2016
22
Development and Application of Diagnostics in the National Schistosomiasis Control Programme in The People's Republic of China. ( 27137454 )
2016
23
Protection and immunological study on two tetraspanin-derived vaccine candidates against schistosomiasis japonicum. ( 27189226 )
2016
24
The Accuracy of Praziquantel Dose Poles for Mass Treatment of Schistosomiasis in School Girls in KwaZulu-Natal, South Africa. ( 27139497 )
2016
25
Towards the Elimination of Schistosomiasis japonica through Control of the Disease in Domestic Animals in The People's Republic of China: A Tale of over 60Years. ( 27137450 )
2016
26
Experiences and perspectives of community health workers from implementing treatment for schistosomiasis using the community directed intervention strategy in an informal settlement in Kisumu City, western Kenya. ( 27634152 )
2016
27
Multi-host model and threshold of intermediate host Oncomelania snail density for eliminating schistosomiasis transmission in China. ( 27535177 )
2016
28
Cervical cytology as a diagnostic tool for female genital schistosomiasis: Correlation to cervical atypia and Schistosoma polymerase chain reaction. ( 27168759 )
2016
29
Receptor Antagonist of IL-13 Exerts a Potential Negative Regulation During Early Infection of Human Schistosomiasis. ( 27507682 )
2016
30
Diagnostic Tests to Support Late-Stage Control Programs for Schistosomiasis and Soil-Transmitted Helminthiases. ( 28005900 )
2016
31
LOW PREVALENCE OF INTESTINAL SCHISTOSOMIASIS AMONG FISHERFOLK LIVING ALONG THE RIVER NILE IN NORTH-WESTERN UGANDA: A BIOSOCIAL INVESTIGATION. ( 27428067 )
2016
32
Health Education as an Important Component in the National Schistosomiasis Control Programme in The People's Republic of China. ( 27137451 )
2016
33
Expanding Praziquantel (PZQ) Access beyond Mass Drug Administration Programs: Paving a Way Forward for a Pediatric PZQ Formulation for Schistosomiasis. ( 27658198 )
2016
34
Toxoplasma gondii GRA15II effector-induced M1 cells ameliorate liver fibrosis in mice infected with Schistosomiasis japonica. ( 27157496 )
2016
35
Hydrology and density feedbacks control the ecology of intermediate hosts of schistosomiasis across habitats in seasonal climates. ( 27162339 )
2016
36
Population Pharmacokinetics and Pharmacodynamics of Praziquantel in Ugandan Children with Intestinal Schistosomiasis: Higher Dosages Are Required for Maximal Efficacy. ( 27507822 )
2016
37
Decline in transmission of schistosomiasis mansoni in Oman. ( 27955687 )
2016
38
Acute abdomen and schistosomiasis: A letter to the editor. ( 27531682 )
2016
39
Schistosomiasis transmission in Europe. ( 27197550 )
2016
40
Estrogen metabolites for the diagnosis of schistosomiasis associated urinary bladder cancer. ( 27014746 )
2016
41
An extensive burden of giardiasis associated with intestinal schistosomiasis and anaemia in school children on the shoreline of Lake Albert, Uganda. ( 27864517 )
2016
42
Factors influencing community participation in control and related operational research for urogenital schistosomiasis and soil-transmitted helminths in rural villages of Kwale County, coastal Kenya. ( 27642474 )
2016
43
Non-necrotizing colonic granuloma induced by schistosomiasis. ( 27987283 )
2016
44
Evaluation of Lethal Giant Larvae as a Schistosomiasis Vaccine Candidate. ( 27957496 )
2016
45
Urogenital schistosomiasis transmission on Unguja Island, Zanzibar: characterisation of persistent hot-spots. ( 27986092 )
2016
46
Treatment of Schistosomiasis in a Patient Allergic to Praziquantel: A Praziquantel Desensitization and Treatment Protocol. ( 27573630 )
2016
47
Knowledge and awareness of genital involvement and reproductive health consequences of urogenital schistosomiasis in endemic communities in Ghana: a cross-sectional study. ( 27655032 )
2016
48
Outbreak of urogenital schistosomiasis in Corsica (France): an epidemiological case study. ( 27197551 )
2016
49
Assessment of schistosomiasis in the semi-arid Northeast region of Brazil: the SALo Francisco River large-scale water transposition project. ( 27192599 )
2016
50
Praziquantel for schistosomiasis in pregnancy. ( 27599647 )
2016

Variations for Schistosomiasis

Expression for Schistosomiasis

Search GEO for disease gene expression data for Schistosomiasis.

Pathways for Schistosomiasis

Pathways related to Schistosomiasis according to GeneCards Suite gene sharing:

(show top 50) (show all 56)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
14.09 ARG1 CD40LG CD79A IFNG IFNGR1 IGHE
2
Show member pathways
13.72 CD40LG F2 IFNG IFNGR1 IL10 IL13
3
Show member pathways
13.61 F2 IFNG IFNGR1 IL10 IL13 IL2
4
Show member pathways
13.46 CD40LG IL10 IL13 IL2 IL4 IL5
5
Show member pathways
13.43 CD40LG IFNG IFNGR1 IGHE IL10 IL13
6
Show member pathways
13.33 CD40LG IL10 IL13 IL2 IL4 IL5
7
Show member pathways
13.25 CD79A IFNG IFNGR1 IL2 IL4 STAT6
8
Show member pathways
12.95 IFNG IFNGR1 IL10 IL2 STAT6 TNF
9
Show member pathways
12.86 IFNG IFNGR1 IL13 IL2 IL4 TNF
10
Show member pathways
12.84 CD40LG IFNG IL10 IL13 IL2 IL4
11
Show member pathways
12.71 CD40LG CD79A IFNG IFNGR1 IGHE IL10
12
Show member pathways
12.68 F2 IFNG IL10 IL2 STAT6 TNF
13
Show member pathways
12.67 CD79A IGHE IL13 IL4 IL5 TNF
14 12.65 CD40LG CD79A IFNG IL10 IL2 IL4
15
Show member pathways
12.62 IFNG IFNGR1 IL10 IL13 IL2 IL4
16
Show member pathways
12.57 IFNG IFNGR1 IL2 IL4 TNF
17
Show member pathways
12.53 CD40LG IFNG IL10 IL2 IL4 IL5
18
Show member pathways
12.43 ALB F2 IFNG IL2 IL4 TNF
19
Show member pathways
12.41 IFNG IL13 IL4 IL5 TNF
20
Show member pathways
12.36 CD40LG IFNG IFNGR1 IL10 IL4 TNF
21 12.27 IFNG IFNGR1 IL10 TNF
22
Show member pathways
12.23 IFNG IFNGR1 IL4 TNF
23
Show member pathways
12.23 IFNG IL10 IL13 IL2 IL4 IL5
24 12.22 GAPDH IL10 IL13 TNF
25
Show member pathways
12.21 IFNG IFNGR1 IL10 IL13 IL2 IL4
26 12.11 ARG1 IFNG IL2 IL4 TNF
27 12.1 IGHE IL10 IL13 IL4 STAT6 TNF
28 12.07 CD79A IFNG IL10 IL2 IL4 IL5
29
Show member pathways
12.06 IFNG IFNGR1 IL10 IL2 TNF
30
Show member pathways
12.04 IFNG IL2 IL4 STAT6
31 11.96 ARG1 IFNG IL10 TNF
32 11.92 IFNG IL13 IL2 IL4 IL5
33
Show member pathways
11.87 CD40LG IFNG IL2 IL4 IL5 TNF
34 11.85 IFNG IL10 IL2 TNF
35 11.84 CD40LG IL10 IL4 IL5 TNF
36 11.82 IFNG IFNGR1 IL10 IL2 STAT6
37 11.77 IFNG IL10 IL13 IL2 IL4 IL5
38 11.76 IL13 IL4 IL5 TNF
39
Show member pathways
11.75 CD40LG IFNG IL2 TNF
40
Show member pathways
11.68 IFNG IL2 TNF
41 11.64 IL10 IL13 IL4 TNF
42 11.63 CD40LG IFNG IL10 TNF
43 11.6 IFNG IL2 TNF
44 11.6 ARG1 CD40LG IGHE IL10 IL4 IL5
45
Show member pathways
11.58 IFNG IFNGR1 TNF
46 11.56 IFNG IL2 TNF
47
Show member pathways
11.54 IFNG IL10 IL2 TNF
48 11.45 CD40LG IFNG IL2 IL4 IL5
49 11.43 IFNG IL13 IL4 IL5 TNF
50 11.41 IFNG IL10 TNF

GO Terms for Schistosomiasis

Cellular components related to Schistosomiasis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 blood microparticle GO:0072562 9.56 ALB F2 IGHE SERPINF2
2 external side of plasma membrane GO:0009897 9.56 CD40LG CD79A F2 IFNG IGHE IL13
3 extracellular space GO:0005615 9.44 ALB ARG1 CD40LG F2 IFNG IL10
4 extracellular region GO:0005576 10 ALB ARG1 CD40LG F2 IFNG IGHE

Biological processes related to Schistosomiasis according to GeneCards Suite gene sharing:

(show all 37)
id Name GO ID Score Top Affiliating Genes
1 cellular response to lipopolysaccharide GO:0071222 9.91 ARG1 IFNG IL10 TNF
2 defense response to bacterium GO:0042742 9.89 IFNG IGHE IL10 RNASE3 TNF
3 positive regulation of smooth muscle cell proliferation GO:0048661 9.84 IL13 SERPINF2 TNF
4 positive regulation of sequence-specific DNA binding transcription factor activity GO:0051091 9.84 IL10 IL4 IL5 TNF
5 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.81 IFNG IL2 IL4
6 B cell proliferation GO:0042100 9.77 CD40LG CD79A IL10
7 positive regulation of protein phosphorylation GO:0001934 9.77 F2 IFNG IL2 IL4 TNF
8 positive regulation of cytokine secretion GO:0050715 9.73 GAPDH IL10 TNF
9 B cell differentiation GO:0030183 9.73 CD40LG CD79A IL10 IL4
10 negative regulation of endothelial cell apoptotic process GO:2000352 9.72 IL10 IL13 IL4
11 positive regulation of T cell proliferation GO:0042102 9.71 CD40LG IFNG IL2 IL4
12 positive regulation of mast cell degranulation GO:0043306 9.67 IL13 IL4
13 negative regulation of fibrinolysis GO:0051918 9.67 F2 SERPINF2
14 endothelial cell apoptotic process GO:0072577 9.67 IL10 TNF
15 positive regulation of immunoglobulin production GO:0002639 9.66 IL13 IL4
16 negative regulation of cytokine secretion involved in immune response GO:0002740 9.65 IL10 TNF
17 defense response to protozoan GO:0042832 9.65 IFNG IL10 IL4
18 type 2 immune response GO:0042092 9.64 IL10 IL4
19 regulation of immunoglobulin secretion GO:0051023 9.63 CD40LG TNF
20 regulation of isotype switching GO:0045191 9.63 IL10 IL4
21 negative regulation of growth of symbiont in host GO:0044130 9.63 IFNG IL10 TNF
22 regulation of proton transport GO:0010155 9.62 IL13 IL4
23 negative regulation of T-helper 17 cell differentiation GO:2000320 9.62 IL2 IL4
24 positive regulation of mononuclear cell migration GO:0071677 9.61 IL4 TNF
25 receptor biosynthetic process GO:0032800 9.59 IL10 TNF
26 negative regulation of complement-dependent cytotoxicity GO:1903660 9.58 IL13 IL4
27 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.58 IFNG TNF
28 positive regulation of isotype switching to IgE isotypes GO:0048295 9.57 IL4 STAT6
29 positive regulation of vitamin D biosynthetic process GO:0060557 9.52 IFNG TNF
30 T-helper 1 cell lineage commitment GO:0002296 9.51 IL4 STAT6
31 positive regulation of chemokine biosynthetic process GO:0045080 9.5 IFNG IL4 TNF
32 positive regulation of isotype switching to IgG isotypes GO:0048304 9.43 IFNG IL2 IL4
33 positive regulation of MHC class II biosynthetic process GO:0045348 9.33 IFNG IL10 IL4
34 immune response GO:0006955 9.28 CD40LG IFNG IGHE IL10 IL13 IL2
35 positive regulation of B cell proliferation GO:0030890 9.26 IL13 IL2 IL4 IL5
36 positive regulation of transcription from RNA polymerase II promoter GO:0045944 10.19 IFNG IL10 IL2 IL4 SERPINF2 STAT6
37 inflammatory response GO:0006954 10.05 CD40LG IL10 IL13 IL5 TNF

Molecular functions related to Schistosomiasis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 growth factor activity GO:0008083 9.35 F2 IL10 IL2 IL4 IL5
2 cytokine activity GO:0005125 9.23 CD40LG IFNG IL10 IL13 IL2 IL4

Sources for Schistosomiasis

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