MCID: SCH004
MIFTS: 25

Schizoid Personality Disorder malady

Categories: Mental diseases

Aliases & Classifications for Schizoid Personality Disorder

Aliases & Descriptions for Schizoid Personality Disorder:

Name: Schizoid Personality Disorder 12 42 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:10936
ICD10 33 F60.1
ICD9CM 35 301.2 301.20
MeSH 42 D012557
NCIt 47 C92631
UMLS 69 C0036339

Summaries for Schizoid Personality Disorder

Disease Ontology : 12 A personality disorder that is characterized by a lack of interest in social relationships, a tendency towards a solitary lifestyle, secretiveness, emotional coldness and sometimes sexual apathy, with a simultaneous rich, elaborate and exclusively internal fantasy world.

MalaCards based summary : Schizoid Personality Disorder is related to personality disorder and neurogenic bladder. An important gene associated with Schizoid Personality Disorder is PIR (Pirin), and among its related pathways/superpathways are Monoamine GPCRs and Serotonergic synapse. The drug Silicon has been mentioned in the context of this disorder.

Wikipedia : 71 Schizoid personality disorder (SPD) is a personality disorder characterized by a lack of interest in... more...

Related Diseases for Schizoid Personality Disorder

Diseases related to Schizoid Personality Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 28)
id Related Disease Score Top Affiliating Genes
1 personality disorder 30.6 HTR1A HTR2A
2 neurogenic bladder 10.2 HTR2A PIR
3 adult brainstem astrocytoma 10.1 HTR1A PIR
4 kidney pelvis papillary carcinoma 10.1 HTR1A PIR
5 polyneuropathy 10.1 HTR1A HTR2A
6 aryepiglottic fold cancer 10.1 HTR1A HTR2A
7 dry eye syndrome 10.1 HTR1A HTR2A
8 waardenburg's syndrome 10.1 HTR1A HTR2A
9 allergic hypersensitivity disease 10.1 HTR1A HTR2A
10 xanthomatosis 10.1 MME PIR
11 vascular cancer 10.1 HTR1A HTR2A
12 hypoglycemic coma 10.1 HTR1A HTR2A
13 multiple personality disorder 10.1 HTR1A HTR2A
14 primary angle-closure glaucoma 10.1 HTR1A HTR2A
15 hepatitis b reinfection following liver transplantation 10.1 HTR1A HTR2A
16 postencephalitic parkinson disease 10.1 HTR1A HTR2A
17 keratosis 10.1 HTR1A HTR2A
18 alzheimer disease 17 10.1 HTR1A HTR2A
19 cecal benign neoplasm 10.0 HTR1A HTR2A
20 lichen disease 10.0 HTR1A HTR2A
21 fechtner syndrome 10.0 HTR1A HTR2A
22 hepatitis d 10.0 HTR1A HTR2A
23 retinoblastoma 10.0 HTR1A HTR2A
24 luxation of globe 10.0 HTR1A SMOC1
25 chronic conjunctivitis 9.9 HTR1A HTR2A
26 alexithymia 9.9
27 benign epilepsy with centrotemporal spikes 9.9 HTR1A HTR2A
28 antisocial personality disorder 9.2 AVEN HTR1A HTR2A MME PIR SMOC1

Comorbidity relations with Schizoid Personality Disorder via Phenotypic Disease Network (PDN):


Acute Cystitis Schizophreniform Disorder

Graphical network of the top 20 diseases related to Schizoid Personality Disorder:



Diseases related to Schizoid Personality Disorder

Symptoms & Phenotypes for Schizoid Personality Disorder

Drugs & Therapeutics for Schizoid Personality Disorder

Drugs for Schizoid Personality Disorder (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Silicon 7440-21-3 4082203

Interventional clinical trials:


id Name Status NCT ID Phase
1 Personality Pathology and Cerebral Processing in Eating Disorders Recruiting NCT02980120

Search NIH Clinical Center for Schizoid Personality Disorder

Cochrane evidence based reviews: schizoid personality disorder

Genetic Tests for Schizoid Personality Disorder

Anatomical Context for Schizoid Personality Disorder

Publications for Schizoid Personality Disorder

Articles related to Schizoid Personality Disorder:

(show all 12)
id Title Authors Year
1
Poor Validity of the DSM-IV Schizoid Personality Disorder Construct as a Diagnostic Category. ( 25248009 )
2014
2
Are alexithymia and schizoid personality disorder synonymous diagnoses? ( 23021894 )
2013
3
Schizoid Personality Disorder. ( 22928849 )
2012
4
Failures of the 'moral defence' in the films Shutter Island, Inception and Memento: narcissism or schizoid personality disorder? ( 22320143 )
2012
5
Schizoid personality disorder. ( 23281676 )
2012
6
Does change in temperament predict change in schizoid personality disorder? A methodological framework and illustration from the Longitudinal Study of Personality Disorders. ( 19825265 )
2009
7
"I am not complaining"--ambivalence construct in schizoid personality disorder. ( 19711768 )
2009
8
Assessing interpersonal aspects of schizoid personality disorder: preliminary validation studies. ( 18444113 )
2008
9
Low body weight in male children and adolescents with schizoid personality disorder or Asperger's disorder. ( 9259226 )
1997
10
Schizoid personality disorder after prenatal exposure to famine. ( 8942466 )
1996
11
Lifelong eccentricity and social isolation. II: Asperger's syndrome or schizoid personality disorder? ( 3256377 )
1988
12
Schizoid personality disorder: a synthesis of developmental, dynamic, and descriptive features. ( 3324773 )
1987

Variations for Schizoid Personality Disorder

Expression for Schizoid Personality Disorder

Search GEO for disease gene expression data for Schizoid Personality Disorder.

Pathways for Schizoid Personality Disorder

Pathways related to Schizoid Personality Disorder according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1
Show member pathways
11.22 HTR1A HTR2A
2 11.01 HTR1A HTR2A
3 10.07 HTR1A HTR2A

GO Terms for Schizoid Personality Disorder

Biological processes related to Schizoid Personality Disorder according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 sensory perception of pain GO:0019233 9.32 HTR2A MME
2 behavior GO:0007610 9.26 HTR1A HTR2A
3 regulation of behavior GO:0050795 9.16 HTR1A HTR2A
4 serotonin receptor signaling pathway GO:0007210 8.96 HTR1A HTR2A
5 regulation of hormone secretion GO:0046883 8.62 HTR1A HTR2A

Molecular functions related to Schizoid Personality Disorder according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 G-protein coupled serotonin receptor activity GO:0004993 9.16 HTR1A HTR2A
2 neurotransmitter receptor activity GO:0030594 8.96 HTR1A HTR2A
3 serotonin binding GO:0051378 8.62 HTR1A HTR2A

Sources for Schizoid Personality Disorder

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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