Schizophrenia malady

MedlinePlus: Schizophrenia is a severe, lifelong brain disorder. people who have it may hear voices, see things that aren't there or believe that others are reading or controlling their minds. in men, symptoms usually start in the late teens and early 20s. they include hallucinations, or seeing things, and delusions such as hearing voices. for women, they start in the mid-20s to early 30s. other symptoms include unusual thoughts or perceptions disorders of movement difficulty speaking and expressing emotion problems with attention, memory and organization no one is sure what causes schizophrenia, but your genetic makeup and brain chemistry probably play a role. medicines can relieve many of the symptoms, but it can take several tries before you find the right drug. you can reduce relapses by staying on your medicine for as long as your doctor recommends. with treatment, many people improve enough to lead satisfying lives. nih: national institute of mental health²³

MalaCards: Schizophrenia, also known as schizophrenia 1 (disorder), is related to neuronitis and prostatitis. An important gene associated with Schizophrenia is DISC1 (disrupted in schizophrenia 1), and among its related pathways are Metabolic pathways and Neuroactive ligand-receptor interaction. The drugs haloperidol decanoate and olanzapine and the compounds calcium and nmda have been mentioned in the context of this disorder. Affiliated tissues include whole blood, brain and cortex, and related mouse phenotypes are homeostasis/metabolism and normal.

Disease Ontology: A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.⁶

Wikipedia: Schizophrenia (/ˌskɪtsɵˈfrɛniə/ or /ˌskɪtsɵˈfriːniə/) is a mental disorder characterized by...⁴⁴ more...

OMIM: 181500

Aliases & Descriptions:

schizophrenia 6 7 16 8 33 32 23 43 schizophrenia 1 (disorder) 43

schizophrenia-1 6

Disease types for schizophrenia family:

schizophrenia 4	schizophrenia 14
schizophrenia 12	schizophrenia 13

Diseases related to schizophrenia by text searches and GeneDecks gene sharing:

(show top 50)    (show all 868)

id	Related Disease	Score	Top Affiliating Genes
1	neuronitis	233.7	PIP5K1B, PINK1, PIK3R1, PICK1, PIK3C2G, PIK3CG
2	prostatitis	143.1	PINK1, PIK3R1, PIK3C2G, PIK3CG, PIK3C3, LRP2
3	bipolar disorder	126.5	ZNF365, ZNF804A, PIP4K2A, PIK3C3, RFX2, NCAM1
4	leukemia	125.5	ZNF230, PIK3R1, PIK3CG, SH3GL2, KLF5, NDE1
5	cerebritis	123.5	PIK3R1, PICK1, PIK3CG, LRP2, NDE1, NDEL1
6	carcinoma	116.4	ZNF706, ZNF124, PIK3R1, PIK3CG, PIK3C3, LRP2
7	cholesterol	104.9	PIK3R1, PIK3C2G, PIK3CG, PIK3C3, LRP2, KLF5
8	hypoxia	95.0	PIK3R1, PIK3CG, KLF5, PDE4A, RET, VRK2
9	arthritis	91.7	PIK3CG, LRP2, KLF12, KLF5, NDEL1, PDE4A
10	obesity	88.5	PIK3R1, PIK3CG, PID1, NCOR2, PDE10A, CNR1
11	hypertension	87.8	PIK3R1, PIK3CG, KLF5, NCAM1, PDE4A, RET
12	dementia	84.1	PINK1, PIK3CG, NCAM1, PDE4A, RELN, PCNA
13	diabetes mellitus	82.4	PIK3R1, PIK3CG, PDE4A, RET, CNDP1, CNR1
14	hepatitis	80.1	PI4KA, PIK3R1, PIK3CG, PIK3C3, RFX2, NCAM1
15	pancreatitis	79.5	PIK3R1, PIK3CG, LRP2, KLF12, KLF5, NCAM1
16	neurodegeneration	74.6	PINK1, PIK3CG, PIK3C3, LRP2, RELN, CNR1
17	seizures	74.4	CNP, CNR1, CNTF, CNTNAP2, SERPINI1, VLDLR
18	mood disorder	74.2	PDE4A, RELN, CNR1, VIPR2, CLOCK, PBRM1
19	ataxia	72.2	ZNF804A, PIP5K1B, PIK3R1, PICK1, PIK3CG, LRP2
20	blindness	68.5	PIK3CG, PDE4A, CNR1, CNTF, SEPP1, VEGFA
21	huntington's disease	68.4	PDE10A, CNR1, CNTF, RCAN1, PCM1, RBMXL1
22	insulin resistance	67.8	PIK3R1, PIK3CG, CNR1, CNTF, PCNT, PCK1
23	neuroblastoma	67.3	PIK3R1, PIK3CG, NCAM1, NCOA7, NCOR2, PDE4A
24	lateral sclerosis	66.9	CNR1, CNR2, CNTF, CNTN4, KIFAP3, SETD2
25	down syndrome	66.9	WDR1, NCAM1, RET, CNP, CNR1, CNR2
26	adenocarcinoma	66.0	PIK3R1, PIK3CG, PIK3C3, NCAM1, RET, CNR1
27	parkinson's disease	65.4	PINK1, CNR1, CNTF, GCH1, SERPINA3, SEPT4
28	amyotrophic lateral sclerosis	65.3	CNR1, CNR2, CNTF, CNTN4, KIFAP3, SETD2
29	neurodegenerative disease	65.0	PINK1, PIK3CG, NCAM1, RELN, CNR1, CNTF
30	anorexia nervosa	62.9	LRP2, NCS1, CNR1, CNR2, CNTN4, VIM
31	thyroiditis	61.0	ZNF197, PIK3R1, PIK3CG, LRP2, NCAM1, NCOA7
32	melanoma	60.7	PIK3R1, PIK3CG, KLF5, NCAM1, PDE4A, PDE4B
33	retinitis	60.3	PIK3CG, LRP2, PDE4A, CNR1, CNR2, CNTF
34	hepatocellular carcinoma	59.7	PIK3R1, PIK3CG, NCAM1, RELN, RET, SGCE
35	major depressive disorder	59.4	PDE4A, PDE4B, CNR1, PCNT, VEGFA, MYT1L
36	autism spectrum disorder	59.0	PIK3CG, RELN, CNR1, CNR2, CNTN4, CNTNAP2
37	alcohol dependence	57.5	NCAM1, SGCE, CNR1, PAX6, BDNF, LEP
38	herpes simplex	56.5	PIK3CG, KIF5B, KIF1A, PCNA, GC, VIM
39	influenza	55.6	ZNF17, PIK3R1, PIK3CG, RARA, RAB11A, LITAF
40	type 2 diabetes mellitus	55.5	PIK3R1, CNR1, CNR2, PCK1, GC, VEGFA
41	ischemia	55.1	PIK3CG, NCAM1, PDE4A, CNR1, CNR2, CNTF
42	brain injury	54.5	NCAM1, CNR1, VSNL1, SERPINI1, VEGFA, BMP6
43	malaria	54.2	PIK3C3, NCOA7, PDE10A, PDE4A, PDE4B, CNTF
44	gonococcal synovitis	53.9	PIK3R1, PIK3CG, NCAM1, PDE4A, CNR1, CNR2
45	twinning	53.9	PIK3R1, NCAM1, SGCE, BRCA2, VEGFA, LPL
46	homocysteine	53.8	PIK3R1, PCNA, PCMT1, SETD2, SERPINA3, NAALAD2
47	gastric cancer	53.4	PIK3R1, PIK3CG, KLF12, KLF5, RELN, KIAA0182
48	bipolar affective disorder	51.7	PIP4K2A, NCAM1, BRD1, VAMP2, BDNF, KCNN1
49	colon cancer	51.7	PIK3R1, PIK3CG, KLF5, NCAM1, NCOR2, PDE4A
50	ovarian cancer	51.5	PIK3R1, PIK3CG, NCAM1, NCOR2, CNTN4, RCAN1

Clinical features from OMIM: 181500

Approved drugs:

Drug clinical trials:

Inferred drug relations via UMLS/NDF-RT:

^43 28 acetophenazine, acetophenazine maleate, aripiprazole, carbamazepine, chlorpromazine, chlorpromazine hydrochloride, clonazepam, clozapine, cyproheptadine, cyproheptadine hydrochloride, cyproheptadine hydrochloride monohydrate, deserpidine, fluphenazine, fluphenazine decanoate, fluphenazine enanthate, fluphenazine hydrochloride, haloperidol, haloperidol decanoate, haloperidol lactate, mesoridazine, mesoridazine besylate, molindone, molindone hydrochloride, olanzapine, perphenazine, piperacetazine, reserpine, risperidone, selegiline, selegiline hydrochloride, thioridazine, thioridazine hydrochloride, thiothixene, thiothixene hydrochloride, trifluoperazine, trifluoperazine hydrochloride, ziprasidone, ziprasidone hydrochloride, ziprasidone mesylate

Genetic tests related to schizophrenia:

id	Genetic test	Affiliating Genes
1	Schizophrenia clinical/research	FXYD6, PRODH, PRODH2, TAAR6

MalaCards organs/tissues related to schizophrenia:

²²

MGI Mouse Phenotypes related to schizophrenia:

²⁵ (show all 30)

id	Description	MGI Source Accession	Score	Top Affiliating Genes
1	homeostasis/metabolism phenotype	MP:0005376	INF	PINK1, PIK3R1, PIK3CG, PIK3C3, WDR1, LRP2
2	normal phenotype	MP:0002873	45.4	PI4KA, PIK3R1, PIK3C3, KLF5, RET, KIF3C
3	vision/eye phenotype	MP:0005391	37.1	LRP2, NCAM1, RELN, CNP, KIF3A, VLDLR
4	no phenotypic analysis	MP:0003012	32.9	PINK1, PIK3R1, LRP2, NCS1, RET, CNR1
5	embryogenesis phenotype	MP:0005380	30.5	PIK3C3, KLF5, NDEL1, RET, KIFAP3, KIF5B
6	skeleton phenotype	MP:0005390	29.1	PIK3CG, WDR1, LRP2, CNP, CNR1, KIF3A
7	adipose tissue phenotype	MP:0005375	27.9	PIK3R1, NCOR2, CNR1, PCK1, NBEA, VLDLR
8	endocrine/exocrine gland phenotype	MP:0005379	26.5	PIP5K1B, PINK1, PICK1, LRP2, KLF5, RET
9	respiratory system phenotype	MP:0005388	26.4	LRP2, KLF5, RET, CNP, KIFAP3, KIF5A
10	hearing/vestibular/ear phenotype	MP:0005377	25.6	WDR1, LRP2, BSN, VDR, RARG, RARA
11	liver/biliary system phenotype	MP:0005370	24.6	PIK3C3, NCOR2, KIFAP3, PCK1, GCLC, RB1CC1
12	craniofacial phenotype	MP:0005382	23.3	LRP2, NCOR2, KIF3A, LPAR1, LMNB2, RARG
13	limbs/digits/tail phenotype	MP:0005371	22.7	RET, KIF3A, PCNT, SEPP1, BRCA2, VEGFA
14	other phenotype	MP:0005395	15.3	CNR1, VPS35, RARG, RARA, RARB, BLOC1S6
15	pigmentation phenotype	MP:0001186	15.2	VLDLR, BLOC1S3, BLOC1S4, BLOC1S5, BLOC1S6, ZIC2
16	taste/olfaction phenotype	MP:0005394	14.9	PDE4A, CNR1, CNTNAP2, PAX6, BDNF, FYN
17	behavior/neurological phenotype	MP:0005386	INF	PINK1, PIK3C3, LRP2, NCAM1, NCOR2, PDE10A
18	mortality/aging	MP:0010768	INF	PIK3C3, WDR1, KLF5, NDEL1, NCAM1, NCOR2
19	immune system phenotype	MP:0005387	INF	PIP5K1B, PINK1, PIK3C3, WDR1, KLF5, PDE4A
20	muscle phenotype	MP:0005369	INF	PIK3R1, PIK3CG, PIK3C3, KLF5, RELN, RET
21	tumorigenesis	MP:0002006	INF	PIK3R1, RET, RCAN1, BRCA2, RARA, LIG4
22	cardiovascular system phenotype	MP:0005385	INF	PIK3R1, PIK3CG, PIK3C3, KLF5, NCOR2, PDE4A
23	reproductive system phenotype	MP:0005389	INF	PIP5K1B, PICK1, RET, CNP, RCAN1, SEPP1
24	growth/size phenotype	MP:0005378	INF	PINK1, PIK3R1, PIK3CG, PIK3C3, WDR1, LRP2
25	digestive/alimentary phenotype	MP:0005381	INF	LRP2, KLF5, NCOR2, RELN, RET, CNP
26	hematopoietic system phenotype	MP:0005397	INF	PIP5K1B, WDR1, CNTF, KIFAP3, RCAN1, PCNA
27	nervous system phenotype	MP:0003631	INF	PICK1, NDE1, NDEL1, PDE4A, PDE4B, RELN
28	integument phenotype	MP:0010771	INF	PIK3CG, WDR1, RELN, CNR1, CNR2, CNTNAP2
29	cellular phenotype	MP:0005384	INF	PINK1, PIK3R1, PICK1, PIK3CG, PIK3C3, WDR1
30	renal/urinary system phenotype	MP:0005367	INF	LRP2, RET, KIF3A, RARA, RARB, UTRN

Articles related to schizophrenia:

(show top 50)    (show all 3241)

id	Title	Authors	Year	Affiliating Genes
1	Application of systems biology approach identifies an d validates GRB2 as a risk gene for schizophrenia in the Irish Case Control Stu dy of Schizophrenia (ICCSS) sample. (21195589)	Sun J.... Zhao Z.	2011	GRB2
2	Novel schizophrenia risk gene TCF4 influences verbal learning and memory functioning in schizophrenia patients. (21228604)	Lennertz L.... MAPssner R.	2011	TCF4
3	The schizophrenia risk allele C of the TCF4 rs9960767 polymorphism disrupts sensorimotor gating in schizophrenia spectrum and health y volunteers. (21543597)	Quednow B.B.... Kumari V.	2011	TCF4
4	Association study between Disrupted-in-Schizophrenia- 1 (DISC1) and Japanese patients with treatment-resistant schizophrenia (TRS). (21256178)	Hotta Y.... Arai H.	2011	DISC1
5	Replication of association between schizophrenia and ZNF804A in the Irish Case-Control Study of Schizophrenia sample. (19844207)	Riley B.... Kendler K.S.	2010	NOS1, RPGRIP1L, ZNF804A
6	Association of Disrupted in Schizophrenia 1 (DISC1) m issense variants with ultra-resistant schizophrenia. (20531374)	Mouaffak F.... Krebs M.O.	2010	DISC1
7	Association analysis of the PIP4K2A gene on chromosom e 10p12 and schizophrenia in the Irish study of high density schizophrenia fami lies (ISHDSF) and the Irish case-control study of schizophrenia (ICCSS). (19475563)	Thiselton D.L.... Riley B.P.	2010	DTNBP1, PIP4K2A
8	Expression analyses of the mitochondrial complex I 75 -kDa subunit in early onset schizophrenia and autism spectrum disorder: increas ed levels as a potential biomarker for early onset schizophrenia. (19894076)	Taurines R.... Mehler-Wex C.	2010	NDUFS4
9	Evidence for the association of the DAOA (G72) gene w ith schizophrenia and bipolar disorder but not for the association of the DAO g ene with schizophrenia. (19586533)	Bass N.J.... Gurling H.M.	2009	DAO, DAOA
10	Neuregulin 1, brain region specificity and PI3K/Akt i n schizophrenia: comment on 'Neuregulin 1 ICE-single nucleotide polymorphi sm in first episode schizophrenia correlates with cerebral activation in fronto -temporal area'. (19224109)	Huang X.F.... Chen J.	2009	NRG1
11	The dystrobrevin binding protein 1 (DTNBP1) gene is a ssociated with schizophrenia in the Irish Case Control Study of Schizophrenia ( ICCSS) sample. (19800201)	Riley B.... Kendler K.S.	2009	DTNBP1
12	Association between genes of Disrupted in schizophrenia 1 (DISC1) interactors and schizophrenia supports the role of the DISC1 pathway in the etiology of major mental illnesses. (19251251)	Tomppo L.... Peltonen L.	2009	PDE4B, PAFAH1B1, PDE4D
13	The Disrupted-in-Schizophrenia-1 Ser704Cys polymorphism and brain morphology in schizophrenia. (19304459)	Takahashi T.... Ozaki N.	2009	DISC1
14	Cannabis and schizophrenia: towards a cannabinoid hypothesis of schizophrenia. (18590475)	MA1ller-Vahl K.R.... Emrich H.M.	2008	CNR1
15	Association between a disrupted-in-schizophrenia 1 (DISC1) single nucleotide polymorphism and schizophrenia in a combined Scandinavian case-control sample. (18818052)	Saetre P.... Jonsson E.G.	2008	DISC1
16	A comparison of the synaptic proteome in human chronic schizophrenia and rat ketamine psychosis suggest that prohibitin is involved in the synaptic pathology of schizophrenia. (18504422)	Smalla K.H.... Kreutz M.R.	2008	PHB
17	Double-blind comparison of first- and second-generati on antipsychotics in early-onset schizophrenia and schizo-affective disorder: f indings from the treatment of early-onset schizophrenia spectrum disorders (TEO SS) study. (18794207)	Sikich L.... Lieberman J.A.	2008	INS
18	The trace amine associated receptor (TAAR6) gene is not associated with schizophrenia in the Irish Case-Control Study of Schizophrenia (ICCSS) sample. (18973992)	Vladimirov V.I.... Riley B.P.	2008	TAAR6
19	AKT1 is associated with schizophrenia across multiple symptom dimensions in the Irish study of high density schizophrenia families. (17825267)	Thiselton D.L.... Riley B.P.	2008	AKT1
20	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia. (17043677)	Camargo L.M.... Brandon N.J.	2007	PGK1, YWHAE, CCNA2
21	Molecular mechanism of schizophrenia with reference to disrupted-in-schizophrenia 1 (DISC1). (17664024)	Matsuzaki S.... Tohyama M.	2007	ADCYAP1, PCNT, DISC1
22	Positive association of the Disrupted-in-Schizophrenia-1 gene (DISC1) with schizophrenia in the Chinese Han population. (17286247)	Qu M.... Zhang D.	2007	DISC1
23	Abnormal changes of plasma acute phase proteins in schizophrenia and the relation between schizophrenia and haptoglobin (Hp) gene. (16897611)	Wan C.... He L.	2007	HP
24	Association analyses of the DAOA/G30 and D-amino-acid oxidase genes in schizophrenia: further evidence for a role in schizophrenia. (17627036)	Shinkai T.... Kennedy J.L.	2007	DAO, DAOA
25	Increased plasma glutamate by antipsychotic medication and its relationship to glutaminase 1 and 2 genotypes in schizophrenia -- Juntendo University Schizophrenia Projects (JUSP). (17669570)	Maeshima H.... Arai H.	2007	GLS, GLS2
26	Case-control association study of Disrupted-in-Schizophrenia-1 (DISC1) gene and schizophrenia in the Chinese population. (16524593)	Chen Q.Y.... He L.	2007	DISC1
27	Disrupted in schizophrenia 1 genotype and positive symptoms in schizophrenia. (17054920)	DeRosse P.... Malhotra A.K.	2007	DISC1
28	A region of 35 kb containing the trace amine associate receptor 6 (TAAR6) gene is associated with schizophrenia in the Irish study of high-density schizophrenia families. (17505468)	Vladimirov V.... Riley B.P.	2007	TAAR6
29	Genetic analysis of the TrkB gene and schizophrenia in the Japanese population: Juntendo University Schizophrenia Projects (JUSP). (17720314)	Higashi M.... Arai H.	2007	NTRK2
30	Significant support for DAO as a schizophrenia susceptibility locus: examination of five genes putatively associated with schizophrenia. (17055463)	Wood L.S.... DeChairo B.M.	2007	DAO, DTNBP1, DISC1
31	The association of the HOPA(12bp) polymorphism with schizophrenia in the NIMH Genetics Initiative for Schizophrenia sample. (17299734)	Philibert R.A.... Black D.W.	2007	MED12
32	Serotonin transporter characteristics in lymphocytes and platelets of male aggressive schizophrenia patients compared to non-aggressive schizophrenia patients. (16713194)	Barkan T.... Rehavi M.	2006	SLC6A4
33	A frameshift mutation in Disrupted in Schizophrenia 1 in an American family with schizophrenia and schizoaffective disorder. (15940305)	Sachs N.A.... Margolis R.L.	2005	DISC1
34	Gene, gut and schizophrenia: the meeting point for the gene-environment interaction in developing schizophrenia. (15617864)	Wei J.... Hemmings G.P.	2005	HLA-DQB1, CLDN5
35	Disrupted in schizophrenia 1 (DISC1): association with schizophrenia, schizoaffective disorder, and bipolar disorder. (15386212)	Hodgkinson C.A.... Malhotra A.K.	2004	DISC1
36	Insulin resistance and increased leptin concentrations in noncompliant schizophrenia patients but not in antipsychotic-naive first-episode schizophrenia patients. (15491236)	Arranz B.... San L.	2004	LEP
37	Disrupted in Schizophrenia 1 and Nudel form a neurodevelopmentally regulated protein complex: implications for schizophrenia and other major neurological disorders. (14962739)	Brandon N.J.... Whiting P.J.	2004	PAFAH1B1, DISC1, NDEL1
38	Decreased serum levels of D-serine in patients with schizophrenia: evidence in support of the N-methyl-D-aspartate receptor hypofunction hypothesis of schizophrenia. (12796220)	Hashimoto K.... Iyo M.	2003	SRR
39	Disrupted-In-Schizophrenia 1, a candidate gene for schizophrenia, participates in neurite outgrowth. (12874605)	Miyoshi K.... Tohyama M.	2003	ACTG1, DISC1, FEZ1
40	Gene expression analysis in schizophrenia: reproducible up-regulation of several members of the apolipoprotein L family located in a high-susceptibility locus for schizophrenia on chromosome 22. (11930015)	Mimmack M.L.... Bahn S.	2002	APOL1, APOL3
41	Angiotensin converting enzyme gene insertion/deletion polymorphism: case-control association studies in schizophrenia, major affective disorder, and tardive dyskinesia and a family-based association study in schizophrenia. (11920854)	Segman R.H.... Lerer B.	2002	ACE
42	Genomic structure and localisation within a linkage hotspot of Disrupted In Schizophrenia 1, a gene disrupted by a translocation segregating with schizophrenia. (11317219)	Millar J.K.... Porteous D.J.	2001	DISC1
43	Identification of polymorphisms within Disrupted in Schizophrenia 1 and Disrupted in Schizophrenia 2, and an investigation of their association with schizophrenia and bipolar affective disorder. (11525420)	Devon R.S.... Porteous D.J.	2001	DISC1
44	Mutation and association analysis of the 5' region of the dopamine D3 receptor gene in schizophrenia patients: identification of the Ala38Thr polymorphism and suggested association between DRD3 haplotypes and schizophrenia. (10889555)	Ishiguro H.... Arinami T.	2000	DRD3
45	Dopamine- and serotonin-receptors in schizophrenia: results of imaging-studies and implications for pharmacotherapy in schizophrenia. (10654113)	Kasper S.... Quiner S.	1999	HTR3A, HTR1A
46	Meta-analysis of association between the 5-HT2a receptor T102C polymorphism and schizophrenia. EMASS Collaborative Group. European Multicentre Association Study of Schizophrenia. (9130948)	Williams J.... Owen M.J.	1997	HTR2A
47	Linkage analysis of the fragile X gene FMR-1 and schizophrenia: no evidence for linkage but report of a family with schizophrenia and an unstable triplet repeat. (8840394)	Ashworth A.... Collier D.A.	1996	FMR1
48	Evidence for a schizophrenia vulnerability locus on chromosome 8p in the Irish Study of High-Density Schizophrenia Families. (8942448)	Kendler K.S.... Straub R.E.	1996	SCZD6
49	Association between schizophrenia and T102C polymorphism of the 5-hydroxytryptamine type 2a-receptor gene. European Multicentre Association Study of Schizophrenia (EMASS) Group. (8622505)	Williams J.... Owen M.J.	1996	HTR2A
50	Association study of schizophrenia with dopamine D3 receptor gene polymorphisms: probable effects of family history of schizophrenia? (8135304)	Nimgaonkar V.L.... Chakravarti A.	1993	DRD3

Genes related to schizophrenia according to GeneCards:

(show top 50)    (show all 1580)

id	Symbol	Description	Score	GeneCards Section Context
1	DISC1	disrupted in schizophrenia 1	11.1	Publications, Transcripts, Aliases & Descriptions, Proteins (show all 6 sections) Orthologs, Summaries
2	DAOA	D-amino acid oxidase activator	11.1	Publications, Aliases & Descriptions, Summaries
3	DISC2	disrupted in schizophrenia 2 (non-protein coding)	11.1	Publications, Transcripts, Aliases & Descriptions, Summaries
4	CHRNA7	cholinergic receptor, nicotinic, alpha 7 (neuronal)	11.0	Publications, Technologies, Orthologs, Summaries
5	NRG1	neuregulin 1	11.0	Publications, Summaries
6	PRODH	proline dehydrogenase (oxidase) 1	11.0	Publications, Summaries
7	HTR2A	5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled	11.0	Publications, Functions, Summaries
8	DRD2	dopamine receptor D2	11.0	Publications, Functions, Summaries
9	TSNAX-DISC1	TSNAX-DISC1 readthrough	11.0	Summaries, Publications
10	SYN3	synapsin III	11.0	Summaries, Publications
11	SCZD14	schizophrenia, susceptibility to, 14	11.0	Aliases & Descriptions
12	DRD4	dopamine receptor D4	11.0	Publications, Summaries
13	TPH1	tryptophan hydroxylase 1	11.0	Publications, Summaries
14	SCZD4	schizophrenia disorder 4	11.0	Publications, Aliases & Descriptions
15	SCZD13	schizophrenia 13	11.0	Aliases & Descriptions
16	DAO	D-amino-acid oxidase	11.0	Publications, Summaries
17	DTNBP1	dystrobrevin binding protein 1	11.0	Publications, Summaries
18	NOTCH4	notch 4	11.0	Publications, Summaries
19	SYN2	synapsin II	11.0	Publications, Summaries
20	SCZD2	schizophrenia disorder 2	11.0	Publications, Aliases & Descriptions
21	RGS4	regulator of G-protein signaling 4	11.0	Publications, Aliases & Descriptions
22	TAAR6	trace amine associated receptor 6	11.0	Publications, Summaries
23	ZDHHC8	zinc finger, DHHC-type containing 8	11.0	Publications, UniProt Related, Summaries
24	DGCR6	DiGeorge syndrome critical region gene 6	11.0	Publications, Summaries
25	FZD3	frizzled family receptor 3	11.0	Publications, Summaries
26	KCNN3	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3	11.0	Publications, Summaries
27	SLC6A1	solute carrier family 6 (neurotransmitter transporter, GABA), member 1	11.0	Publications, Summaries
28	SLC6A9	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	11.0	Publications, Summaries
29	UHMK1	U2AF homology motif (UHM) kinase 1	11.0	Publications, Summaries
30	YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	11.0	Publications, Summaries
31	CLINT1	clathrin interactor 1	11.0	Publications, Summaries
32	GABBR1	gamma-aminobutyric acid (GABA) B receptor, 1	11.0	Publications, Summaries
33	GRIK3	glutamate receptor, ionotropic, kainate 3	11.0	Publications, Summaries
34	RELN	reelin	11.0	Publications, Expressions, Summaries
35	SLC1A3	solute carrier family 1 (glial high affinity glutamate transporter), member 3	11.0	Publications, Summaries
36	CACNG2	calcium channel, voltage-dependent, gamma subunit 2	11.0	Publications, Summaries
37	GRIA4	glutamate receptor, ionotropic, AMPA 4	11.0	Publications, Summaries
38	NPAS3	neuronal PAS domain protein 3	11.0	Publications, Functions, Summaries
39	PDE4B	phosphodiesterase 4B, cAMP-specific	11.0	Publications, Summaries
40	SLC1A1	solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1	11.0	Publications, Summaries
41	SLC1A2	solute carrier family 1 (glial high affinity glutamate transporter), member 2	11.0	Publications, Summaries
42	NRG3	neuregulin 3	11.0	Publications, Summaries
43	SCZD12	schizophrenia 12	11.0	Aliases & Descriptions, Publications
44	SCZD11	Schizophrenia susceptibility locus, chromosome 10q-related	11.0	Publications, Aliases & Descriptions
45	SCZD5	schizophrenia disorder 5	11.0	Publications, Aliases & Descriptions
46	SCZD8	schizophrenia disorder 8	11.0	Aliases & Descriptions, Publications
47	SCZD1	schizophrenia disorder 1	11.0	Publications, Aliases & Descriptions
48	SCZD6	schizophrenia disorder 6	11.0	Publications, Aliases & Descriptions
49	SCZD10	schizophrenia disorder 10 (periodic catatonia)	11.0	Publications, Aliases & Descriptions
50	SCZD7	schizophrenia disorder 7	11.0	Publications, Aliases & Descriptions

Pathways related to schizophrenia according to GeneDecks:

(show top 50)    (show all 182)

id	Pathway	Score	Top Affiliating Genes
1	Metabolic pathways20	36.3	PI4KA, PIP5K1B, PIK3C2G, PIK3C3, CNDP1, PCK1
2	Neuroactive ligand-receptor interaction20	28.8	CNR1, CNR2, VIPR2, LPAR1, PARD3, LEP
3	Neuroscience3	28.1	PINK1, NCAM1, NCS1, RET, CNP, CNTNAP2
4	cAMP Pathway36	24.1	PIK3R1, SEMA3A, BMP6, BDNF, KDR, YWHAB
5	Molecular Mechanisms of Cancer36	22.8	PIK3R1, PIK3C2G, PIK3CG, SEMA3A, BMP6, RARA
6	Activation of cAMP-Dependent PKA36	22.1	SEMA3A, BMP6, BDNF, KDR, YWHAB, YWHAE
7	Akt Signaling36	21.0	PIK3R1, PIK3CG, SEMA3A, MUSK, MST1R, ATF4
8	Antioxidant Action of Vitamin-C36	20.9	SEMA3A, MYO18B, MYO1D, MYO9B, BMP6, BDNF
9	Glutamatergic synapse20	20.7	CHP1, JMJD7-PLA2G4B, GRIA1, GRIA2, GRIA3, GRIA4
10	ERK Signaling36	20.7	PIK3R1, SEMA3A, BRF1, BMP6, PAX6, PAK2
11	MAPK Signaling36	20.7	PIK3R1, SEMA3A, BMP6, PAK2, PAK3, BDNF
12	p38 Signaling36	20.6	SEMA3A, BMP6, BDNF, KDR, BCL2, MUSK
13	Activation of PKA through GPCR36	20.5	SEMA3A, BMP6, BDNF, KDR, YWHAB, YWHAE
14	Rho Family GTPases36	20.0	PIP5K1B, PIK3R1, SEMA3A, VIM, BMP6, PAK2
15	Phospholipase-C Pathway36	19.8	SEMA3A, BMP6, BDNF, KDR, LAMA2, LAMB2
16	Tec Kinases Signaling36	19.7	PIK3R1, SEMA3A, BMP6, PAK2, PAK3, BDNF
17	CREB Pathway36	19.4	PIK3R1, SEMA3A, BMP6, BDNF, KDR, ATF4
18	JAK-STAT Pathway36	19.4	PIK3R1, SEMA3A, BMP6, BDNF, KDR, BCL2
19	eNOS Signaling36	19.3	PIK3R1, SEMA3A, BMP6, BDNF, CHRNA6, CHRNA7
20	MAPK signaling pathway20	18.7	PAK2, BDNF, CHP1, ATF4, ATF2, JUN
21	MAPK Family Pathway36	18.7	PIK3R1, SEMA3A, BMP6, PAK2, BDNF, KDR
22	NFAT in Immune Response36	18.5	PIK3R1, SEMA3A, BMP6, BDNF, KDR, MUSK
23	p70S6K Signaling36	18.4	PIK3R1, SEMA3A, BMP6, BDNF, KDR, YWHAB
24	ILK Signaling36	18.3	PIK3R1, SEMA3A, VIM, MYO18B, MYO1D, MYO9B
25	Estrogen Pathway36	18.2	PIK3R1, NCOR2, SEMA3A, BMP6, BDNF, KDR
26	GPCR Pathway36	18.2	PIK3R1, SEMA3A, BMP6, PAK2, PAK3, BDNF
27	DHA Signaling36	17.7	PIK3R1, SEMA3A, BMP6, BIK, BDNF, KDR
28	Breast Cancer Regulation by Stathmin136	17.5	PIK3R1, RB1CC1, SEMA3A, MUSK, MST1R, ARHGEF10
29	Signaling Involved in Cardiac Hypertrophy36	17.5	PIK3R1, ATF4, ATF2, JUN, ITGA3, IRS1
30	TGF-Beta Pathway36	16.7	PIK3R1, SEMA3A, BMP6, BDNF, KDR, BCL2
31	Axon guidance38	16.7	SH3GL2, NCAN, SEMA3A, MYL12B, UNC5C, KCNQ2
32	14-3-3 Induced Intracellular Signaling36	16.7	PIK3R1, SEMA3A, BDNF, YWHAB, YWHAE, YWHAG
33	JNK Pathway36	16.6	PIK3R1, BMP6, PAK2, PAK3, KDR, BCL2
34	Glutamic acid signaling10	16.5	GRIA1, GRIA2, GRIA3, GRIA4, GRID1, GRIK1
35	Renin-Angiotensin Pathway36	16.2	PIK3R1, SEMA3A, BMP6, PAK2, PAK3, BDNF
36	Signaling in Gap Junctions36	16.1	PIK3R1, GRB2, GRM1, GRM2, GRM3, GRM4
37	Endothelin-1 Signaling Pathway36	15.8	PIK3R1, BMP6, MUSK, MST1R, INSR, FGFR2
38	Neurophysiological process_Glutamate regulation of Dopamine D1A receptor signaling41	15.3	CDK5R1, GRIA1, GRIA2, GRIA3, GRIA4, GRIN1
39	Neurophysiological process Glutamate regulation of Dopamine D1A receptor signaling10	15.2	CDK5R1, GRIA1, GRIA2, GRIA3, GRIA4, GRIN1
40	PGC1Alpha Pathway36	15.0	BMP6, BCL2, ATF4, INSR, IL10RA, IL12A
41	Cholinergic synapse20	14.8	PIK3R1, PIK3CG, BCL2, KCNQ2, KCNQ5, CHRNA6
42	Neuronal System38	14.7	PICK1, PANX2, KCNN2, KCNMA1, KCNN1, KCNN3
43	GABA signaling in brain10	14.6	MECP2, GNAI2, NRXN1, NRXN2, NRXN3, NLGN1
44	Pathways in cancer20	14.4	PIK3R1, PIK3CG, RET, BRCA2, VEGFA, RARA
45	Amyotrophic lateral sclerosis (ALS)20	13.5	BCL2, CHP1, GRIA1, GRIA2, GRIN1, GRIN2A
46	Dopamine-DARPP32 Feedback onto cAMP Pathway36	INF	PAWR, KCNE1, KCNH2, KCNH5, KCNJ9, KCNE2
47	Glucose / Energy Metabolism3	INF	PIK3C3, , IRS1, INSR, GSK3A, GSK3B
48	Calcium signaling pathway20	INF	CHRNA7, CHRM5, CHP1, CHRM1, CHRM3, P2RX7
49	Intracellular Calcium Signaling36	INF	SEMA3A, BMP6, BDNF, KDR, CHRNA6, CHRNA7
50	Alzheimers disease20	INF	LPL, UQCRC1, CHP1, BACE1, , ATP5H

Compounds related to schizophrenia according to GeneDecks:

(show top 50)    (show all 565)

id	Compound	Score	Top Affiliating Genes
1	calcium32 9 18 9	44.7	PICK1, NCS1, PDE4A, RELN, CNR1, CNTF
2	nmda32 42	40.1	PICK1, NCAM1, PDE4A, RELN, CNR1, VIM
3	cysteine32	38.0	PCNA, GCLC, SERPINA1, SEPHS1, SEPP1, SERPINA3
4	adenylate32	35.5	PIK3CG, PDE4A, CNP, CNR1, CNR2, CNTF
5	creatinine32	27.9	NCAM1, PCNA, GC, SERPINA1, SERPINA3, VLDLR
6	adp32 18	27.4	PI4KA, PIP5K1B, PINK1, PIK3C2G, PIK3CG, PIP4K2A
7	hydrogen32 18	27.3	PDE4A, CNR2, VAMP2, RARA, PAH, PAM
8	leucine32	25.1	PIK3R1, RET, SERPINA3, VIM, RARS, PAWR
9	histamine32 18	25.8	NCAM1, PDE4A, CNR1, CNTF, PCNA, VIM
10	cisplatin32 34 9 9	26.8	CNR2, PCNA, GCLC, GCLM, SETD2, BRCA2
11	iron32 18	24.0	LRP2, SETD2, SERPINA1, SERPINA3, VIM, PAH
12	actinomycin d32	22.8	PIK3CG, PDE4A, CNTF, SETD2, VIM, VEGFA
13	choline32 9 18 9	23.8	RET, CNTF, VIM, BCHE, LEPR, CHRNA7
14	haloperidol32 34 9 9	22.8	BDNF, KCNH2, KCNJ5, CHAT, CHGA, FOS
15	valine32	19.6	RET, SERPINA3, VIM, LPL, PAH, BDNF
16	doxorubicin32 34 9 9	22.6	PIK3CG, NCAM1, SETD2, VIM, BMP6, BIRC2
17	prostaglandin32	19.3	PDE4A, CNTF, VIM, KCNJ5, SCT, UCP2
18	estradiol32 9 18 9	22.2	NCOR2, PCNA, GC, SERPINA3, VIM, BRCA2
19	polysaccharide32	18.9	NCAM1, SERPINA1, SERPINA3, LPL, BPI, BMP6
20	formaldehyde32 18	19.3	PCNA, VIM, CHAT, CHGA, S100B, B2M
21	folate32	17.9	LRP2, GCH1, SERPINA3, VIM, NAT1, NAT2
22	prostacyclin32	17.9	PDE4A, VEGFA, BMP6, KDR, KCNMA1, LEP
23	gnrh32	17.6	NCAM1, VIM, LEP, LEPR, KAL1, AR
24	lysine32	17.6	SERPINA1, PARK7, PAH, KDM1A, KCNH2, SCT
25	histidine32	17.5	PDE4A, RARA, LIPF, PAM, KCNH2, SCT
26	isoproterenol32 9 9	19.2	PIK3R1, PDE4A, VIM, KCNH2, KCNMA1, SCT
27	corticosterone32 18	18.1	CNR1, BDNF, BCL2A1, LEPR, ITIH4, FOS
28	6-hydroxydopamine32	17.0	PARK7, BDNF, CHAT, FOS, GSR, FGF1
29	sb 20358032 42	17.3	SETD2, VIM, VEGFA, VDR, BMP6, BIRC2
30	pyruvate32	16.0	SETD2, CKB, CHAT, CHKB, UCP2, MT-ND1
31	diazepam32 34 9 9	19.0	BDNF, CCKBR, PTGS1, CYP1A2, CYP3A4, CYP2C19
32	matrigel32	16.0	PIK3R1, PIK3CG, NCAM1, VIM, VEGFA, BMP6
33	sodium nitroprusside32	15.8	PDE4A, PCNA, BMP6, KCNJ5, KCNMA1, CHAT
34	manganese superoxide32	15.8	UCP2, XRCC1, ATM, CD14, GSR, GSTM1
35	5fluorouracil32	15.5	PIK3CG, PCNA, VEGFA, VDR, BIRC2, KDR
36	phenylalanine32	15.5	PIK3R1, GCH1, BDNF, CHRNA4, UGT1A1, LBR
37	calcitriol32 42 9 18 9	19.5	LRP2, GC, VDR, BMP6, RARA, RARS
38	neopterin32	15.4	GCH1, PAH, CHKB, LBR, B2M, QDPR
39	4-hydroxynonenal32 18	16.1	GCLC, GCLM, CHAT, UCP2, BACE1, XDH
40	mifepristone32 42 9 9	17.9	NCOR2, BCL2A1, LBR, JUN, MMP3, IRS1
41	bupropion32 34 9 18 9	18.7	CNR1, CNTF, CHRNA3, ANKK1, MAOB, GHRL
42	thalidomide32 42 9 9	17.3	PDE4A, VEGFA, BIRC2, KDR, B2M, CD40LG
43	naloxone32 34 9 9	17.1	CNR1, VIM, KCNJ5, LEP, FOS, IL1A
44	celecoxib32 42 34 9 18 9	17.9	PIK3R1, PIK3CG, PCNA, VEGFA, KDR, BCL2
45	geldanamycin32 9 9	14.7	PIK3R1, PIK3CG, SETD2, VEGFA, KDR, FYN
46	glycogen32 18	INF	PIK3R1, PIK3CG, RELN, PCK1, SETD2, VIM
47	tacrolimus32 34 9 9	INF	RCAN1, PCNA, VDR, BMP6, BCL2A1, CHKB
48	thapsigargin32 42	INF	PIK3CG, CNR1, PCNA, BDNF, BCL2, KCNMA1
49	ribonucleic acid32	INF	RET, BMP6, RARA, RARB, CLU, LEPR
50	oxygen32 18	INF	GCH1, SETD2, SERPINA1, SEPP1, SERPINA3, CLU

Cellular components related to schizophrenia according to GeneDecks:

(show all 24)

id	Name	GO ID	Score	Top Affiliating Genes
1	cytoplasm	GO:005737	63.2	PICK1, PIK3CG, PID1, WDR11, SH3BP5, SH3GL2
2	nucleus	GO:005634	60.5	ZNF211, ZNF197, ZNF17, ZNF451, ZNF490, ZNF184
3	cytosol	GO:005829	54.4	PI4KA, PIP5K1B, PINK1, PIK3R1, PIK3C2G, PIK3CG
4	extracellular region	GO:005576	32.4	WDR1, NCAM1, NCAN, CNDP1, CNTN4, PCDHA1
5	cell junction	GO:030054	27.0	PICK1, NCS1, PCDH8, BSN, VAMP2, UTRN
6	extracellular space	GO:005615	26.4	LRP2, RELN, CNP, CNTF, GC, SERPINA1
7	postsynaptic membrane	GO:045211	23.9	NCS1, CNKSR2, PCDH8, UTRN, CHRFAM7A, CHRNA6
8	nucleoplasm	GO:005654	22.4	NCOR2, PCNA, BRCA2, BRF1, VDR, RARG
9	neuronal cell body	GO:043025	21.8	CNKSR2, CNTF, CNTNAP2, VGF, PAFAH1B1, CHRNA3
10	perinuclear region of cytoplasm	GO:048471	21.3	PICK1, NCS1, PDE4A, PDE4B, CNP, KIF5B
11	axon	GO:030424	19.4	NCS1, CNTF, CNTN4, CNTNAP2, GC, SEMA3A
12	dendrite	GO:030425	18.4	RELN, CNR2, CNTNAP2, PCDH8, SEMA3A, BSN
13	cell surface	GO:009986	18.1	NCAM1, CNTNAP2, VLDLR, VEGFA, LPAR1, LPL
14	postsynaptic density	GO:014069	18.0	PICK1, NCS1, CHRNA3, CHRM1, CHRM4, YWHAZ
15	neuron projection	GO:043005	15.4	CNKSR2, KIF5B, VGF, VAMP2, GRIN1, GRIN2B
16	terminal button	GO:043195	14.8	P2RX7, GRIA2, GRIA3, GRIA4, GRIK2, GRIK3
17	membrane raft	GO:045121	14.7	PAG1, P2RX7, ATP2B2, CD79A, CD14, CD48
18	presynaptic membrane	GO:042734	14.6	PICK1, PCDH8, GRIA2, GRIK2, GRIK4, GRIK5
19	synapse	GO:045202	14.3	PICK1, BCAN, INSR, GRIN1, GRIN3A, APC
20	perikaryon	GO:043204	14.0	CNR2, CNTNAP2, PAM, GRIA2, GRIA3, GRIK2
21	secretory granule	GO:030141	12.8	BRCA2, VEGFA, PAM, CHGB, CHGA, INS
22	membrane	GO:016020	INF	PIP5K1B, PIK3C2G, PIK3CG, PDE4A, CNTNAP2, KIF5A
23	integral to plasma membrane	GO:005887	INF	RET, SGCE, CNR1, CNR2, KIR3DL2, PCDH11X
24	plasma membrane	GO:005886	INF	PIK3R1, PICK1, PIK3CG, PIP4K2A, LRP2, SH3GL2

Biological processes related to schizophrenia according to GeneDecks:

(show top 50)    (show all 75)

id	Name	GO ID	Score	Top Affiliating Genes
1	small molecule metabolic process	GO:044281	40.9	PI4KA, PIP5K1B, PIK3R1, PIK3C2G, PIK3CG, PIP4K2A
2	synaptic transmission	GO:007268	36.4	PI4KA, PICK1, CNP, KIF5A, PCDH8, PCDHB11
3	response to drug	GO:042493	23.4	LRP2, PDE4A, GCLM, VLDLR, LPL, BLOC1S3
4	positive regulation of transcription from RNA polymerase II promoter	GO:045944	22.4	PID1, KLF12, NCOA7, VEGFA, VDR, BMP6
5	nervous system development	GO:007399	21.7	NDEL1, CNTN4, KIF2A, PCDHA3, PCDHB11, PCDHA1
6	axon guidance	GO:007411	19.7	SH3GL2, NCAM1, NCAN, RELN, CNTN4, SEMA3A
7	positive regulation of transcription, DNA-dependent	GO:045893	19.4	KLF5, RET, WAC, BRCA2, BRF1, RARA
8	positive regulation of cell proliferation	GO:008284	19.3	KLF5, CNTF, VEGFA, RARA, BLOC1S2, KDR
9	anti-apoptosis	GO:006916	18.0	GCLC, BIRC2, BDNF, BCL2, BCL2A1, YWHAZ
10	inflammatory response	GO:006954	17.8	PIK3CG, CNR2, SERPINA3, BMP6, PARK7, KCNJ10
11	cellular nitrogen compound metabolic process	GO:034641	17.8	GCLC, GCLM, PAH, CKB, MTR, SAT1
12	nerve growth factor receptor signaling pathway	GO:048011	16.6	PIK3R1, SH3GL2, YWHAB, YWHAE, UBC, MTOR
13	response to hypoxia	GO:001666	16.5	SERPINA1, VEGFA, PAM, BCL2, KCNMA1, LEP
14	negative regulation of cell proliferation	GO:008285	16.4	KIFAP3, BTG1, VDR, RARG, RARB, RARRES1
15	negative regulation of apoptotic process	GO:043066	16.1	PIK3CG, RB1CC1, VEGFA, BIRC2, CLU, PAK2
16	central nervous system development	GO:007417	16.0	SH3GL2, RELN, RCAN1, SERPINI1, LIG4, PAX6
17	neurotransmitter secretion	GO:007269	15.9	VAMP2, CHAT, GRM4, MAOA, ALDH5A1, HSPA8
18	negative regulation of neuron apoptotic process	GO:043524	15.6	CNTF, GCLM, LIG4, PARK7, BDNF, BCL2
19	response to ethanol	GO:045471	15.3	CNR1, BCL2, CHAT, CHRNB2, FYN, MMP9
20	glucose metabolic process	GO:006006	15.1	PCK1, LEP, INS, FBP1, MDH1, APOD
21	neuron migration	GO:001764	15.1	RELN, PCNT, PAFAH1B1, PAX6, CHL1, YWHAE
22	aging	GO:007568	15.1	LRP2, CNR1, VDR, MSRA, JUN, GRB2
23	locomotory behavior	GO:007626	14.8	SEPP1, CHRNA3, CHRNB2, CHRNA4, ATP2B2, ASTN1
24	positive regulation of apoptotic process	GO:043065	14.8	CNR1, SEPT4, LPAR1, RARG, RARB, CLU
25	circadian rhythm	GO:007623	14.6	CLOCK, LEP, MTNR1A, JUN, ARNTL, ARNTL2
26	brain development	GO:007420	14.6	RELN, CNTN4, CNTNAP2, SEPP1, SEPT4, BRCA2
27	memory	GO:007613	14.6	CNR1, VLDLR, CHRNA7, CHAT, CHRNB2, MUSK
28	platelet activation	GO:030168	14.6	PIK3R1, PIK3CG, WDR1, SERPINA1, VEGFA, BLOC1S3
29	response to lipopolysaccharide	GO:032496	14.1	CNR1, CNR2, GCH1, SERPINA1, UGT1A1, P2RX7
30	social behavior	GO:035176	14.1	CHRNB2, MSS51, MECP2, GRIN1, IL1B, ANXA7
31	response to cocaine	GO:042220	14.1	CNR1, CHRNB2, GRIN2A, GRIN2B, HTR1B, HTR3A
32	response to amphetamine	GO:001975	14.1	CNR2, GRIN1, GRIN2A, GRIN2B, ICAM1, GNAL
33	response to estradiol stimulus	GO:032355	14.0	GC, SERPINA1, BRCA2, VDR, RARA, PAM
34	regulation of insulin secretion	GO:050796	13.9	CNR1, VAMP2, LEP, CHRM3, MTNR1B, INS
35	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	GO:007187	13.9	CNR1, CNR2, MTNR1A, MTNR1B, MC2R, MC5R
36	axonogenesis	GO:007409	13.5	CNP, CNTN4, PAK3, PARD3, S100B, FGFR2
37	response to organic cyclic compound	GO:014070	13.5	SERPINA1, UGT1A1, P2RX7, JUN, MET, IL1A
38	positive regulation of MAPK cascade	GO:043410	13.4	CNTF, LPAR1, KDR, LEP, P2RX7, AR
39	learning	GO:007612	13.3	BCHE, CHST10, CHRNB2, FYN, JUN, GRM4
40	regulation of excitatory postsynaptic membrane potential	GO:060079	13.3	CHRNA3, MECP2, GRIK2, GRIK5, GRIN1, GRIN2A
41	regulation of long-term neuronal synaptic plasticity	GO:048169	13.0	RAB11A, KCNJ10, GRIK2, GRIN1, GRIN2A, GRIN2B
42	gamma-aminobutyric acid signaling pathway	GO:007214	12.5	CACNA1A, GABBR1, GABBR2, GABRA2, GABRA6, GABRB2
43	anterograde axon cargo transport	GO:008089	12.1	KIF1A, BLOC1S1, BLOC1S2, BLOC1S3, BLOC1S4, BLOC1S5
44	anterograde synaptic vesicle transport	GO:048490	11.2	BLOC1S1, BLOC1S2, BLOC1S3, BLOC1S4, BLOC1S5, BLOC1S6
45	ion transmembrane transport	GO:034220	INF	ATP2B2, , ATP2B4, HTR3A, HTR3B, HTR3C
46	transport	GO:006810	INF	NDEL1, CHRNA6, UCP2, XK, ATP2B2,
47	cell adhesion	GO:007155	INF	NCAM1, NCAN, RELN, CNTN5, CNTNAP2, PCDHA3
48	signal transduction	GO:007165	INF	PI4KA, SH3BP5, SH3GL2, PDE10A, PDE4A, PDE4B
49	transmembrane transport	GO:055085	INF	RAB11A, AVPR2, ATP6V0D1, ATP2B2, , ATP6V1B2
50	blood coagulation	GO:007596	INF	PIK3R1, PIK3CG, WDR1, PDE10A, KIFAP3, KIF3C

Molecular functions related to schizophrenia according to GeneDecks:

(show all 16)

id	Name	GO ID	Score	Top Affiliating Genes
1	protein binding	GO:005515	86.2	ZNF365, PI4KA, PIP5K1B, PINK1, PIK3R1, PICK1
2	protein homodimerization activity	GO:042803	24.8	GCH1, VEGFA, VAPB, MYO9B, BLOC1S6, BHLHE41
3	receptor binding	GO:005102	18.7	PICK1, CNTNAP2, LPL, RARA, LAMA2, P2RX7
4	enzyme binding	GO:019899	17.4	PICK1, CNTNAP2, BTG1, VAPB, RARA, ZFHX3
5	identical protein binding	GO:042802	17.4	PICK1, SH3GL2, PCNA, PCM1, VIM, BLOC1S6
6	protein heterodimerization activity	GO:046982	16.6	GCLM, VEGFA, VAPB, BMP6, RARA, BIK
7	calmodulin binding	GO:005516	15.8	PCNT, VAMP2, MYO1D, MYO9B, KCNH5, KCNN2
8	drug binding	GO:008144	14.6	CNR1, CHRM1, CHRM3, GRIN2B, HTR1A, HTR1B
9	growth factor activity	GO:008083	14.5	CNTF, VGF, VEGFA, BMP6, BDNF, LEP
10	extracellular ligand-gated ion channel activity	GO:005230	13.8	CHRFAM7A, ZACN, HTR3A, HTR3C, HTR3D, HTR3E
11	extracellular-glutamate-gated ion channel activity	GO:005234	13.6	GRIA1, GRIA2, GRIA3, GRIA4, GRID1, GRIK1
12	steroid hormone receptor activity	GO:003707	12.8	VDR, RARG, RARA, RARB, ESR1, ESR2
13	GABA-A receptor activity	GO:004890	12.8	GABRA2, GABRA6, GABRB1, GABRB2, GABRD, GABRG1
14	ATP binding	GO:005524	INF	PI4KA, PIP5K1B, PINK1, PIK3C2G, PIK3CG, PIP4K2A
15	calcium ion binding	GO:005509	INF	LRP2, NCAN, NCS1, RET, SGCE, VSNL1
16	protein C-terminus binding	GO:008022	INF	PICK1, VIM, LIG4, BLOC1S2, YWHAB, XRCC4