MCID: SCH011
MIFTS: 33

Schizotypal Personality Disorder malady

Summaries for Schizotypal Personality Disorder

About this section
Sources:
8Disease Ontology, 63Wikipedia, 32MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
Disease Ontology:8 A personality disorder that involves a need for social isolation, anxiety in social situations, odd behavior and thinking, and often unconventional beliefs.

MalaCards: Schizotypal Personality Disorder, also known as schizotypal personality, is related to schizophrenia and borderline personality disorder. An important gene associated with Schizotypal Personality Disorder is COMT (catechol-O-methyltransferase), and among its related pathways is Metabolism. The compounds pyridoxal 5-phosphate and calcium have been mentioned in the context of this disorder. Affiliated tissues include eye, brain and temporal lobe.

Wikipedia:63 Schizotypal personality disorder is a personality disorder characterized by a need for social isolation,... more...

Aliases & Classifications for Schizotypal Personality Disorder

About this section
Sources:
8Disease Ontology, 10DISEASES, 44Novoseek, 60UMLS, 34MeSH, 27ICD9CM, 56SNOMED-CT
See all sources

Aliases & Descriptions:

schizotypal personality disorder 8 10 44 60
schizotypal personality 44


External Ids:

Disease Ontology8 DOID:10646
MeSH34 D012569
SNOMED-CT56 31027006, 231486008
ICD9CM27 301.22

Related Diseases for Schizotypal Personality Disorder

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Graphical network of the top 20 diseases related to Schizotypal Personality Disorder:



Diseases related to schizotypal personality disorder

Clinical Features for Schizotypal Personality Disorder

About this section

Drugs & Therapeutics for Schizotypal Personality Disorder

About this section
Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Schizotypal Personality Disorder

Drug clinical trials:

Search ClinicalTrials for Schizotypal Personality Disorder

Search NIH Clinical Center for Schizotypal Personality Disorder

Search CenterWatch for Schizotypal Personality Disorder

Genetic Tests for Schizotypal Personality Disorder

About this section

Anatomical Context for Schizotypal Personality Disorder

About this section
Sources:
32MalaCards
See all sources

MalaCards organs/tissues related to Schizotypal Personality Disorder:

32
Eye, Brain, Temporal lobe, Caudate nucleus, Testes, Breast, Pituitary

Animal Models for Schizotypal Personality Disorder or affiliated genes

About this section

Publications for Schizotypal Personality Disorder

About this section
Sources:
50PubMed
See all sources

Articles related to Schizotypal Personality Disorder:

(show top 50)    (show all 174)
idTitleAuthorsYear
1
Visual-spatial working memory performance and temporal gray matter volume predict schizotypal personality disorder group membership. (24398009)
2014
2
Neuroimaging findings in schizotypal personality disorder: a systematic review. (23220094)
2013
3
Semantic processing impairment in individuals with schizotypal personality disorder features: a preliminary event-related potential study. (22960083)
2013
4
Developmental trajectories of schizotypal personality disorder-like behavioural manifestations: a two-year longitudinal prospective study of college students. (24289659)
2013
5
Does a latent class underlie schizotypal personality disorder? Implications for schizophrenia. (23713503)
2013
6
Working memory in schizotypal personality disorder: fMRI activation and deactivation differences. (24161536)
2013
7
Some suggestions for the DSM-5 schizotypal personality disorder construct. (21741634)
2012
8
Smaller superior temporal gyrus volume specificity in schizotypal personality disorder. (19473820)
2009
9
The effects of risperidone on the cognitive performance of individuals with schizotypal personality disorder. (19593186)
2009
10
Shape abnormalities of caudate nucleus in schizotypal personality disorder. (19328654)
2009
11
The heterogeneous structure of schizotypal personality disorder: item-level factors of the Schizotypal Personality Questionnaire and their associations with obsessive-compulsive disorder symptoms, dissociative tendencies, and normal personality. (18489212)
2008
12
Psychological trauma and schizotypal personality disorder. (18729605)
2008
13
Aripiprazole in schizotypal personality disorder: a case report. (19287561)
2008
14
Visual event-related potentials in schizotypal personality disorder and schizophrenia. (18266490)
2008
15
Sex differences in digit ratio (2D:4D) are disrupted in adolescents with schizotypal personality disorder: altered prenatal gonadal hormone levels as a risk factor. (16806835)
2006
16
Cognitive function and symptoms in adolescents with schizotypal personality disorder. (16611879)
2006
17
Catechol-O-methyltransferase Val158Met genotype variation is associated with prefrontal-dependent task performance in schizotypal personality disorder patients and comparison groups. (16691129)
2006
18
Emotional correlates of the different dimensions of schizotypal personality disorder. (16737400)
2006
19
Clinical, cognitive, and social characteristics of a sample of neuroleptic-naive persons with schizotypal personality disorder. (15985362)
2005
20
A comparative profile analysis of neuropsychological function in men and women with schizotypal personality disorder. (15694753)
2005
21
Context-processing deficits in schizotypal personality disorder. (15535788)
2004
22
A MRI study of fusiform gyrus in schizotypal personality disorder. (14511799)
2003
23
Deficient attentional modulation of the startle response in patients with schizotypal personality disorder. (12944337)
2003
24
An MRI study of superior temporal gyrus volume in women with schizotypal personality disorder. (14638590)
2003
25
Reduced processing resource availability in schizotypal personality disorder: evidence from a dual-task CPT study. (12916647)
2003
26
EEG synchronization to modulated auditory tones in schizophrenia, schizoaffective disorder, and schizotypal personality disorder. (14638599)
2003
27
Neurobiological measures of schizotypal personality disorder: defining an inhibitory endophenotype? (11986147)
2002
28
Differential metabolic rates in prefrontal and temporal Brodmann areas in schizophrenia and schizotypal personality disorder. (11853988)
2002
29
Prefrontal structural and functional deficits in schizotypal personality disorder. (12645681)
2002
30
Schizotypal personality disorder inside and outside the schizophrenic spectrum. (11853976)
2002
31
Minnesota Multiphasic Personality Inventory profile characteristics of schizotypal personality disorder. (12109963)
2002
32
Lateralized perceptual organization deficits on the global-local task in schizotypal personality disorder. (11866178)
2002
33
Magnetic resonance imaging of the thalamic mediodorsal nucleus and pulvinar in schizophrenia and schizotypal personality disorder. (11177115)
2001
34
Physostigmine and cognition in schizotypal personality disorder. (11278149)
2001
35
Executive functions in adolescents with schizotypal personality disorder. (10742650)
2000
36
Visuospatial working memory in schizotypal personality disorder patients. (10728721)
2000
37
Social skills deficits in schizotypal personality disorder. (10760382)
2000
38
Visual perception and working memory in schizotypal personality disorder. (10784472)
2000
39
Electrophysiological correlates of language processing in schizotypal personality disorder. (10401451)
1999
40
MRI study of cavum septi pellucidi in schizophrenia, affective disorder, and schizotypal personality disorder. (9545997)
1998
41
Event-related potentials in schizotypal personality disorder. (8845699)
1996
42
Topographic abnormalities of P3 in schizotypal personality disorder. (8830949)
1996
43
Formal thought disorder in childhood onset schizophrenia and schizotypal personality disorder. (2289947)
1990
44
Schizotypal personality disorder in an outpatient population: incidence and clinical characteristics. (3384958)
1988
45
Coexistent obsessive-compulsive disorder and schizotypal personality disorder: a poor prognostic indicator. (3954553)
1986
46
Concomitant obsessive-compulsive disorder and schizotypal personality disorder. (3953896)
1986
47
Schizotypal personality disorder. Chestnut Lodge follow-up study: VI. Long-term follow-up perspectives. (3954556)
1986
48
Schizotypal personality disorder and the insanity defense. (3734726)
1986
49
Relationship of schizotypal personality disorder to schizophrenia: genetics. (3909378)
1985
50
An independent analysis of the Copenhagen sample of the Danish adoption study of schizophrenia. II. The relationship between schizotypal personality disorder and schizophrenia. (7283669)
1981

Genetic Variations for Schizotypal Personality Disorder

About this section

Expression for genes affiliated with Schizotypal Personality Disorder

About this section
Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Schizotypal Personality Disorder

Search GEO for disease gene expression data for Schizotypal Personality Disorder.

Pathways for genes affiliated with Schizotypal Personality Disorder

About this section
Sources:
53Reactome, 29KEGG
See all sources

Pathways related to Schizotypal Personality Disorder according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
8.7LBR, PSAT1, CACNA1C, COMT

Compounds for genes affiliated with Schizotypal Personality Disorder

About this section
Sources:
44Novoseek, 49PharmGKB, 11DrugBank, 24HMDB
See all sources

Compounds related to Schizotypal Personality Disorder according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1pyridoxal 5-phosphate449.5PSAT1, COMT
2calcium44 49 11 2411.1FLNA, ARHGAP32, LBR, PSAT1, CACNA1C

GO Terms for genes affiliated with Schizotypal Personality Disorder

About this section
Sources:
16Gene Ontology
See all sources

Biological processes related to Schizotypal Personality Disorder according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1small molecule metabolic processGO:0442818.4SULT4A1, LBR, PSAT1, CACNA1C, COMT

Products for genes affiliated with Schizotypal Personality Disorder

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Schizotypal Personality Disorder

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet