MCID: SCH010
MIFTS: 24

Schneiderian Carcinoma malady

Categories: Cancer diseases, Respiratory diseases

Aliases & Classifications for Schneiderian Carcinoma

Aliases & Descriptions for Schneiderian Carcinoma:

Name: Schneiderian Carcinoma 12 14 69
Cylindrical Cell Carcinoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4003
NCIt 47 C54287
SNOMED-CT 64 5600009
UMLS 69 C0334270

Summaries for Schneiderian Carcinoma

MalaCards based summary : Schneiderian Carcinoma, also known as cylindrical cell carcinoma, is related to childhood mediastinal neurogenic tumor and deep angioma, and has symptoms including pain and rhinorrhea. An important gene associated with Schneiderian Carcinoma is MAML2 (Mastermind Like Transcriptional Coactivator 2), and among its related pathways/superpathways is Cytoskeleton remodeling Neurofilaments. Affiliated tissues include liver and tonsil, and related phenotype is Decreased shRNA abundance (Z-score < -2).

Related Diseases for Schneiderian Carcinoma

Diseases related to Schneiderian Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 35)
id Related Disease Score Top Affiliating Genes
1 childhood mediastinal neurogenic tumor 10.1 CRTC1 MAML2
2 deep angioma 10.1 CRTC1 MAML2
3 conjunctival intraepithelial neoplasm 10.1 CRTC1 MAML2
4 progeria 10.1 CRTC1 MAML2
5 onychodystrophy-anonychia 10.0 KRT18 KRT5
6 embryonal testis carcinoma 10.0 KRT18 KRT5
7 vulvar alveolar soft part sarcoma 10.0 KRT18 KRT5
8 heavy chain disease 10.0 KRT5 MAML2
9 distal arthrogryposis 10.0 KRT18 KRT5
10 ovarian wilms' cancer 9.9 KRT18 SMUG1
11 mongolian spot 9.9 KRT18 KRT5
12 lower lip cancer 9.9 CRTC1 MAML2
13 prostate lymphoma 9.9 KRT5 SMUG1
14 benign ependymoma 9.9 KRT18 KRT5
15 wells syndrome 9.9 CRTC1 KRT18 MAML2
16 sclerosing breast papilloma 9.9 KRT5 SMUG1
17 familial lipoprotein lipase deficiency 9.9 KRT5 SMUG1
18 lung combined type small cell carcinoma 9.9 CRTC1 KRT5 MAML2
19 plasmodium ovale malaria 9.9 CRTC1 KRT5 MAML2
20 retrograde amnesia 9.9 CRTC1 KRT5 MAML2
21 vaginal endometrial stromal sarcoma 9.8 KRT5 SMUG1
22 tricuspid valve prolapse 9.8 CRTC1 MAML2 SMUG1
23 malignant pleural solitary fibrous tumor 9.8 KRT5 SMUG1
24 sinusitis 9.7
25 endodermal sinus tumor 9.7
26 polycystic liver disease 9.7
27 aspergillosis 9.7
28 liver disease 9.7
29 tonsillitis 9.7
30 papilloma 9.7
31 inverted papilloma 9.7
32 pancreatitis 9.7
33 sinonasal undifferentiated carcinoma 9.7
34 combined thymoma 9.7 KRT5 SMUG1
35 multidrug-resistant tuberculosis 9.4 CRTC1 KRT18 KRT5 MAML2 SMUG1

Graphical network of the top 20 diseases related to Schneiderian Carcinoma:



Diseases related to Schneiderian Carcinoma

Symptoms & Phenotypes for Schneiderian Carcinoma

UMLS symptoms related to Schneiderian Carcinoma:


pain, rhinorrhea

GenomeRNAi Phenotypes related to Schneiderian Carcinoma according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-153 9.66 KRT5
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-154 9.66 KRT18
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-17 9.66 KRT5 KRT18
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-180 9.66 KRT5
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-200 9.66 KRT5
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-33 9.66 KRT18
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-71 9.66 KRT5 KRT18
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-84 9.66 KRT18
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-91 9.66 KRT5

Drugs & Therapeutics for Schneiderian Carcinoma

Interventional clinical trials:


id Name Status NCT ID Phase
1 Intensity-Modulated or Proton Radiation Therapy for Sinonasal Malignancy Recruiting NCT01586767 Phase 2

Search NIH Clinical Center for Schneiderian Carcinoma

Genetic Tests for Schneiderian Carcinoma

Anatomical Context for Schneiderian Carcinoma

MalaCards organs/tissues related to Schneiderian Carcinoma:

39
Liver, Tonsil

Publications for Schneiderian Carcinoma

Articles related to Schneiderian Carcinoma:

id Title Authors Year
1
Hepatobiliary and Pancreatic: A unique case of HPV related metastatic Schneiderian carcinoma presenting as polycystic liver disease. ( 28052462 )
2017
2
Low-grade Papillary Schneiderian Carcinoma, a Unique and Deceptively Bland Malignant Neoplasm: Report of a Case. ( 25634744 )
2015
3
Exophytic schneiderian carcinoma of the lacrimal sac: first case report. ( 24977732 )
2014
4
Schneiderian carcinoma developing in an inverted papilloma of the palatine tonsil: an unusual case. ( 21563078 )
2011
5
Sinonasal undifferentiated carcinoma, or schneiderian carcinoma arising from an aspergillosis: a case history. ( 19211176 )
2009

Variations for Schneiderian Carcinoma

Expression for Schneiderian Carcinoma

Search GEO for disease gene expression data for Schneiderian Carcinoma.

Pathways for Schneiderian Carcinoma

Pathways related to Schneiderian Carcinoma according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1
Show member pathways
10.66 KRT18 KRT5

GO Terms for Schneiderian Carcinoma

Cellular components related to Schneiderian Carcinoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 intermediate filament GO:0005882 8.96 KRT18 KRT5
2 keratin filament GO:0045095 8.62 KRT18 KRT5

Biological processes related to Schneiderian Carcinoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 keratinization GO:0031424 8.96 KRT18 KRT5
2 cornification GO:0070268 8.62 KRT18 KRT5

Molecular functions related to Schneiderian Carcinoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 scaffold protein binding GO:0097110 8.62 KRT18 KRT5

Sources for Schneiderian Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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