MCID: SCH010
MIFTS: 26

Schneiderian Carcinoma

Categories: Cancer diseases, Respiratory diseases

Aliases & Classifications for Schneiderian Carcinoma

MalaCards integrated aliases for Schneiderian Carcinoma:

Name: Schneiderian Carcinoma 12 14 69
Cylindrical Cell Carcinoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4003
NCIt 46 C54287
SNOMED-CT 64 5600009
UMLS 69 C0334270

Summaries for Schneiderian Carcinoma

MalaCards based summary : Schneiderian Carcinoma, also known as cylindrical cell carcinoma, is related to lacrimal gland mucoepidermoid carcinoma and cutaneous mucoepidermoid carcinoma, and has symptoms including rhinorrhea and pain. An important gene associated with Schneiderian Carcinoma is MAML2 (Mastermind Like Transcriptional Coactivator 2), and among its related pathways/superpathways is Cytoskeleton remodeling Neurofilaments. Affiliated tissues include tonsil and liver, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

Related Diseases for Schneiderian Carcinoma

Graphical network of the top 20 diseases related to Schneiderian Carcinoma:



Diseases related to Schneiderian Carcinoma

Symptoms & Phenotypes for Schneiderian Carcinoma

UMLS symptoms related to Schneiderian Carcinoma:


rhinorrhea, pain

GenomeRNAi Phenotypes related to Schneiderian Carcinoma according to GeneCards Suite gene sharing:

25
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-153 9.66 KRT5
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-154 9.66 KRT18
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-17 9.66 KRT18 KRT5
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-180 9.66 KRT5
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-200 9.66 KRT5
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-33 9.66 KRT18
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-71 9.66 KRT5 KRT18
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-84 9.66 KRT18
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-91 9.66 KRT5

Drugs & Therapeutics for Schneiderian Carcinoma

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Intensity-Modulated or Proton Radiation Therapy for Sinonasal Malignancy Active, not recruiting NCT01586767 Phase 2

Search NIH Clinical Center for Schneiderian Carcinoma

Genetic Tests for Schneiderian Carcinoma

Anatomical Context for Schneiderian Carcinoma

MalaCards organs/tissues related to Schneiderian Carcinoma:

38
Tonsil, Liver

Publications for Schneiderian Carcinoma

Articles related to Schneiderian Carcinoma:

# Title Authors Year
1
Hepatobiliary and Pancreatic: A unique case of HPV related metastatic Schneiderian carcinoma presenting as polycystic liver disease. ( 28052462 )
2017
2
Low-Grade Papillary Schneiderian Carcinoma: A Case Report. ( 28639124 )
2017
3
Low-grade Papillary Schneiderian Carcinoma, a Unique and Deceptively Bland Malignant Neoplasm: Report of a Case. ( 25634744 )
2015
4
Exophytic schneiderian carcinoma of the lacrimal sac: first case report. ( 24977732 )
2014
5
Schneiderian carcinoma developing in an inverted papilloma of the palatine tonsil: an unusual case. ( 21563078 )
2011
6
Sinonasal undifferentiated carcinoma, or schneiderian carcinoma arising from an aspergillosis: a case history. ( 19211176 )
2009

Variations for Schneiderian Carcinoma

Expression for Schneiderian Carcinoma

Search GEO for disease gene expression data for Schneiderian Carcinoma.

Pathways for Schneiderian Carcinoma

Pathways related to Schneiderian Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
10.66 KRT18 KRT5

GO Terms for Schneiderian Carcinoma

Cellular components related to Schneiderian Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intermediate filament GO:0005882 8.96 KRT18 KRT5
2 keratin filament GO:0045095 8.62 KRT18 KRT5

Biological processes related to Schneiderian Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 keratinization GO:0031424 8.96 KRT18 KRT5
2 cornification GO:0070268 8.62 KRT18 KRT5

Molecular functions related to Schneiderian Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 scaffold protein binding GO:0097110 8.62 KRT18 KRT5

Sources for Schneiderian Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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