MCID: SCR009
MIFTS: 22

Scirrhous Adenocarcinoma

Categories: Cancer diseases

Aliases & Classifications for Scirrhous Adenocarcinoma

MalaCards integrated aliases for Scirrhous Adenocarcinoma:

Name: Scirrhous Adenocarcinoma 12 14
Adenocarcinoma, Scirrhous 41 69
Adenocarcinoma with Productive Fibrosis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4024
MeSH 41 D002293
NCIt 46 C2928
SNOMED-CT 64 4584002
UMLS 69 C0007135

Summaries for Scirrhous Adenocarcinoma

Disease Ontology : 12 An adenocarcinoma that results in a hard structure owing to the formation of dense connective tissue in the stroma.

MalaCards based summary : Scirrhous Adenocarcinoma, also known as adenocarcinoma, scirrhous, is related to adenocarcinoma and breast apocrine carcinoma. An important gene associated with Scirrhous Adenocarcinoma is PGR (Progesterone Receptor), and among its related pathways/superpathways are Gastric cancer and Signaling by ERBB4. Affiliated tissues include pancreas, liver and colon.

Related Diseases for Scirrhous Adenocarcinoma

Diseases related to Scirrhous Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 54)
# Related Disease Score Top Affiliating Genes
1 adenocarcinoma 10.3
2 breast apocrine carcinoma 9.9 ERBB2 PGR
3 glassy cell carcinoma of the cervix 9.9 ERBB2 PGR
4 intracystic papillary adenoma 9.9 ERBB2 PGR
5 progesterone-receptor negative breast cancer 9.9 ERBB2 PGR
6 breast medullary carcinoma 9.9 ERBB2 PGR
7 breast scirrhous carcinoma 9.9 ERBB2 PGR
8 progesterone-receptor positive breast cancer 9.9 ERBB2 PGR
9 oncocytic breast carcinoma 9.9 ERBB2 PGR
10 apocrine adenocarcinoma 9.9 ERBB2 PGR
11 uterine body mixed cancer 9.9 ERBB2 PGR
12 breast adenoid cystic carcinoma 9.9 ERBB2 PGR
13 breast squamous cell carcinoma 9.9 ERBB2 PGR
14 microglandular adenosis 9.9 ERBB2 PGR
15 luminal breast carcinoma 9.9 ERBB2 PGR
16 breast benign neoplasm 9.9 ERBB2 PGR
17 thoracic benign neoplasm 9.9 ERBB2 PGR
18 uterine corpus cancer 9.9 ERBB2 PGR
19 inflammatory breast carcinoma 9.9 ERBB2 PGR
20 mixed cell type cancer 9.9 ERBB2 PGR
21 lipid-rich carcinoma 9.9 ERBB2 PGR
22 breast secretory carcinoma 9.9 ERBB2 PGR
23 uterine carcinosarcoma 9.9 ERBB2 PGR
24 primary peritoneal carcinoma 9.9 ERBB2 PGR
25 mammary paget's disease 9.9 ERBB2 PGR
26 breast metaplastic carcinoma 9.9 ERBB2 PGR
27 bilateral breast cancer 9.9 ERBB2 PGR
28 tubular adenocarcinoma 9.9 ERBB2 PGR
29 breast papillary carcinoma 9.9 ERBB2 PGR
30 papillary adenocarcinoma 9.9 ERBB2 PGR
31 pre-malignant neoplasm 9.9 ERBB2 PGR
32 triple-receptor negative breast cancer 9.9 ERBB2 PGR
33 fallopian tube carcinoma 9.8 ERBB2 PGR
34 estrogen-receptor negative breast cancer 9.8 ERBB2 PGR
35 sweat gland cancer 9.8 ERBB2 PGR
36 breast fibroadenoma 9.8 ERBB2 PGR
37 in situ carcinoma 9.8 ERBB2 PGR
38 female breast cancer 9.8 ERBB2 PGR
39 malignant ovarian surface epithelial-stromal neoplasm 9.8 ERBB2 PGR
40 ovary epithelial cancer 9.8 ERBB2 PGR
41 breast carcinoma in situ 9.8 ERBB2 PGR
42 estrogen-receptor positive breast cancer 9.8 ERBB2 PGR
43 sporadic breast cancer 9.8 ERBB2 PGR
44 ductal carcinoma in situ 9.8 ERBB2 PGR
45 endometrial adenocarcinoma 9.8 ERBB2 PGR
46 ovarian cancer 1 9.7 ERBB2 PGR
47 female reproductive organ cancer 9.7 ERBB2 PGR
48 papillary carcinoma 9.7 ERBB2 PGR
49 breast disease 9.7 ERBB2 PGR
50 reproductive organ cancer 9.7 ERBB2 PGR

Graphical network of the top 20 diseases related to Scirrhous Adenocarcinoma:



Diseases related to Scirrhous Adenocarcinoma

Symptoms & Phenotypes for Scirrhous Adenocarcinoma

Drugs & Therapeutics for Scirrhous Adenocarcinoma

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Phase II Study to Evaluate Efficacy and Safety of Dovitinib (TKI258) in Advanced Scirrhous Gastric Carcinoma Patients Completed NCT01576380 Phase 2 TKI258

Search NIH Clinical Center for Scirrhous Adenocarcinoma

Cochrane evidence based reviews: adenocarcinoma, scirrhous

Genetic Tests for Scirrhous Adenocarcinoma

Anatomical Context for Scirrhous Adenocarcinoma

MalaCards organs/tissues related to Scirrhous Adenocarcinoma:

38
Pancreas, Liver, Colon

Publications for Scirrhous Adenocarcinoma

Articles related to Scirrhous Adenocarcinoma:

# Title Authors Year
1
Scirrhous adenocarcinoma of the rectum in a cow. ( 8117809 )
1993
2
Immunohistochemical identification of type I procollagen in tumour cells of scirrhous adenocarcinoma of the stomach. ( 2831927 )
1988
3
Primary scirrhous adenocarcinoma of the colon (signet-ring cell type). ( 6274043 )
1981
4
CO-EXISTENT CYSTOSARCOMA PHYLLODES AND SCIRRHOUS ADENOCARCINOMA OF THE BREAST. ( 14080403 )
1963
5
Scirrhous adenocarcinoma arising in a lipomatous pseudohypertrophic pancreas. ( 14441042 )
1960
6
CLINICOPATHOLOGIC conference: scirrhous adenocarcinoma of bile duct with metastases and biliary cirrhosis of liver. ( 13078623 )
1953
7
WEEKLY clinicopathological exercise: scirrhous adenocarcinoma of pancreas with metastases to the liver. ( 14910848 )
1952
8
WEEKLY clinicopathological exercises: scirrhous adenocarcinoma of pancreas. ( 14882472 )
1951

Variations for Scirrhous Adenocarcinoma

Expression for Scirrhous Adenocarcinoma

Search GEO for disease gene expression data for Scirrhous Adenocarcinoma.

Pathways for Scirrhous Adenocarcinoma

Pathways related to Scirrhous Adenocarcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.62 ERBB2 PGR
2
Show member pathways
10.66 ERBB2 PGR

GO Terms for Scirrhous Adenocarcinoma

Sources for Scirrhous Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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