MCID: SCL015
MIFTS: 49

Scleritis malady

Categories: Rare diseases, Eye diseases

Aliases & Classifications for Scleritis

Aliases & Descriptions for Scleritis:

Name: Scleritis 12 50 42 14 69

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Eye diseases


External Ids:

Disease Ontology 12 DOID:13452
ICD10 33 H15.0 H15.00
ICD9CM 35 379.00
MeSH 42 D015423
NCIt 47 C119046
UMLS 69 C0036416

Summaries for Scleritis

MalaCards based summary : Scleritis is related to uveitis and tuberculosis. An important gene associated with Scleritis is TNF (Tumor Necrosis Factor), and among its related pathways/superpathways are TGF-Beta Pathway and Akt Signaling. The drugs Adrenocorticotropic Hormone and beta-endorphin have been mentioned in the context of this disorder. Affiliated tissues include eye, neutrophil and thyroid, and related phenotypes are immune system and hematopoietic system

Wikipedia : 71 Scleritis is a serious inflammatory disease that affects the white outer coating of the eye, known as... more...

Related Diseases for Scleritis

Diseases in the Scleritis family:

Posterior Scleritis Anterior Scleritis

Diseases related to Scleritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 321)
id Related Disease Score Top Affiliating Genes
1 uveitis 30.4 CCL2 TNF
2 tuberculosis 29.8 CCL2 IL4 TNF
3 rheumatoid arthritis 29.3 CCL2 IFNG IL4 ITGB2 TNF
4 exophthalmos 28.9 IFNG IL4 TNF
5 posterior scleritis 12.0
6 anterior scleritis 12.0
7 brawny scleritis 11.9
8 scleroperikeratitis 10.9
9 aortic atherosclerosis 10.3 IL5 TNF
10 natural killer cell leukemia 10.3 IL5 MMP9
11 hepatic encephalopathy 10.3 IL5 TNF
12 slate pneumoconiosis 10.2 CCL2 TNF
13 occupational dermatitis 10.2 MRAP TNF
14 hypotrichosis-lymphedema-telangiectasia-renal defect syndrome 10.2 SELE TNF
15 prostate calculus 10.2 MRAP TNF
16 bladder calculus 10.2 MRAP TNF
17 tubular renal disease-cardiomyopathy syndrome 10.2 IL4 TNF
18 lagophthalmos 10.2 IL4 TNF
19 conidiobolomycosis 10.2 IL4 TNF
20 nephronophthisis 1, juvenile 10.2 MRAP TNF
21 marasmus 10.2 IL4 IL5
22 hypopyon ulcer 10.2 ITGB2 SELE
23 papillary squamous carcinoma 10.2 IL4 IL5
24 vestibule of mouth cancer 10.2 IL4 TNF
25 lens-induced iridocyclitis 10.2 IL4 IL5
26 spastic paraplegia 3a, autosomal dominant 10.2 IL4 IL5
27 hypersensitivity vasculitis 10.1 IL4 IL5
28 infancy electroclinical syndrome 10.1 CCL2 MMP9 TNF
29 optic nerve hypoplasia 10.1 CCL2 MMP9 TNF
30 allescheriosis 10.1 IL4 IL5
31 rectum squamous cell carcinoma 10.1 CCL2 IL5 TNF
32 bone peripheral neuroepithelioma 10.1 IL4 IL5
33 histiocytoma 10.1 ITGB2 MMP9 TNF
34 ectropion 10.1 IL4 MMP9
35 indian plum allergy 10.1 IL4 IL5
36 intratubular embryonal carcinoma 10.1 CCL2 MMP9 TNF
37 luminal breast carcinoma 10.1 IL4 IL5
38 lactose intolerance 10.1 IL4 IL5
39 stocco dos santos syndrome 10.1 IFNG TNF
40 isthmus cancer 10.1 IL4 MMP9
41 gastroschisis abdominal wall defects, included 10.1 IFNG IL5
42 distal trisomy 14q 10.1 IFNG TNF
43 keratitis 10.1
44 severe combined immunodeficiency, t cell-negative, b-cell/natural killer-cell positive 10.1 IFNG TNF
45 right ventricle hypoplasia 10.1 SELE TNF
46 pemphigus vulgaris, familial 10.1 MMP9 SELE TNF
47 choroiditis 10.1
48 cerebral primitive neuroectodermal tumor 10.1 IL4 IL5
49 cervix small cell carcinoma 10.1 MMP9 SELE TNF
50 askin's tumor 10.1 IL4 IL5

Comorbidity relations with Scleritis via Phenotypic Disease Network (PDN):


Rheumatoid Arthritis

Graphical network of the top 20 diseases related to Scleritis:



Diseases related to Scleritis

Symptoms & Phenotypes for Scleritis

MGI Mouse Phenotypes related to Scleritis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 immune system MP:0005387 9.92 CCL2 IFNG IL4 IL5 ITGB2 MMP9
2 hematopoietic system MP:0005397 9.91 IFNG IL4 IL5 ITGB2 MMP9 SELE
3 digestive/alimentary MP:0005381 9.8 IFNG IL4 IL5 MMP9 TNF
4 integument MP:0010771 9.73 TNF IFNG IL4 ITGB2 MMP9 SELE
5 liver/biliary system MP:0005370 9.55 IFNG IL4 IL5 SELE TNF
6 respiratory system MP:0005388 9.43 IFNG IL4 IL5 MMP9 SELE TNF
7 vision/eye MP:0005391 9.1 IFNG IL4 ITGB2 MMP9 SELE TNF

Drugs & Therapeutics for Scleritis

Drugs for Scleritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 62)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1 Adrenocorticotropic Hormone Phase 4
2 beta-endorphin Phase 4
3 Hormone Antagonists Phase 4,Phase 2,Phase 1
4 Hormones Phase 4,Phase 2,Phase 1
5 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 2,Phase 1
6 Melanocyte-Stimulating Hormones Phase 4
7
Ephedrine Approved Phase 1, Phase 2 299-42-3 9294
8
Pseudoephedrine Approved Phase 1, Phase 2 90-82-4 7028
9
rituximab Approved Phase 1, Phase 2 174722-31-7 10201696
10
Infliximab Approved Phase 2,Phase 1 170277-31-3
11
Methotrexate Approved Phase 2 1959-05-2, 59-05-2 126941
12
Everolimus Approved Phase 1, Phase 2 159351-69-6 6442177
13
Miconazole Approved, Investigational, Vet_approved Phase 1, Phase 2 22916-47-8 4189
14
Sirolimus Approved, Investigational Phase 1, Phase 2 53123-88-9 5284616 6436030 46835353
15
Cyclophosphamide Approved, Investigational Phase 2 50-18-0, 6055-19-2 2907
16
Prednisone Approved, Vet_approved Phase 2 53-03-2 5865
17 Autonomic Agents Phase 1, Phase 2
18 Nasal Decongestants Phase 1, Phase 2
19 Ophthalmic Solutions Phase 1, Phase 2
20 Peripheral Nervous System Agents Phase 1, Phase 2
21 Pharmaceutical Solutions Phase 1, Phase 2
22 Respiratory System Agents Phase 1, Phase 2
23 Tetrahydrozoline Phase 1, Phase 2
24 Vasoconstrictor Agents Phase 1, Phase 2
25 Immunosuppressive Agents Phase 1, Phase 2
26 Antirheumatic Agents Phase 1, Phase 2
27 Anti-Bacterial Agents Phase 1, Phase 2
28 Antibiotics, Antitubercular Phase 1, Phase 2
29 Antifungal Agents Phase 1, Phase 2
30 Anti-Infective Agents Phase 1, Phase 2
31 Anti-Inflammatory Agents Phase 2,Phase 1
32 Antineoplastic Agents, Hormonal Phase 2,Phase 1
33 Dermatologic Agents Phase 2,Phase 1
34 Gastrointestinal Agents Phase 2,Phase 1
35 glucocorticoids Phase 2,Phase 1
36 Alkylating Agents Phase 2
37 Antineoplastic Agents, Alkylating Phase 2
38
Dexamethasone Approved, Investigational, Vet_approved Phase 1 50-02-2 5743
39 Antiemetics Phase 1
40 BB 1101 Phase 1
41 Dexamethasone 21-phosphate Phase 1
42 Dexamethasone acetate Phase 1 1177-87-3
43 HIV Protease Inhibitors Phase 1
44
protease inhibitors Phase 1
45
Adalimumab Approved 331731-18-1 16219006
46
Azathioprine Approved 446-86-6 2265
47
Cyclosporine Approved, Investigational, Vet_approved 79217-60-0, 59865-13-3 5284373 6435893
48
Etanercept Approved, Investigational 185243-69-0
49
Methylprednisolone Approved, Vet_approved 83-43-2 6741
50
Mycophenolate mofetil Approved, Investigational 128794-94-5 5281078

Interventional clinical trials:

(show all 19)
id Name Status NCT ID Phase
1 Study of H.P. ACTHAR Subcutaneous Gelatin (Gel)(Highly Purified Gel Injection) in Uveitis Patients Completed NCT02764697 Phase 4
2 Effects of Magnetic Therapy and Seawater Combined in Decreasing Intraocular Presion. Unknown status NCT02300818 Phase 1, Phase 2
3 Gevokizumab for Active Scleritis Completed NCT01835132 Phase 1, Phase 2
4 Sirolimus Injections for Autoimmune Scleritis Completed NCT01517074 Phase 1, Phase 2
5 Rituximab in the Treatment of Scleritis and Non-Infectious Orbital Inflammation Completed NCT00415506 Phase 1, Phase 2
6 Cyclophosphamide vs. Infliximab for Refractory Idiopathic Scleritis (CIRIS) Not yet recruiting NCT03088293 Phase 2
7 Iontophoresis Delivery of Dexamethasone Phosphate for Non-infectious, Non-necrotizing Anterior Scleritis, Phase 1 Dose-varying Study Completed NCT01059955 Phase 1
8 Infliximab to Treat Non-Infectious Scleritis Completed NCT00075075 Phase 1
9 Study Evaluating PSI-697 in Patients With Scleritis Terminated NCT00367692 Phase 1
10 Causes of Visual Loss in Retinal Disease Unknown status NCT01613963
11 Optical Coherence Tomography in the Diagnosis of Scleritis and Episcleritis Completed NCT01958567
12 Perichondrium Autograft in Refractory Necrotizing Scleritis Completed NCT02864823
13 Human Samples and Data Repository Completed NCT00539370
14 Systemic Immunosuppressive Therapy for Eye Diseases (SITE) Cohort Study Completed NCT00116090
15 Evaluation of Biological Biomarkers Diagnostic of Toxoplasmosis Uveitis Completed NCT02843438
16 Influencing Factors in Uveitis Completed NCT00827086
17 Exploring Immune Cell Signatures in Autoimmunity and Dry Eye Syndrome Recruiting NCT02715323
18 Uveitis/Intraocular Inflammatory Disease Biobank (iBank) Recruiting NCT02656381
19 Immune Responses to Antigens in Non-infectious Eye Inflammatory Diseases Enrolling by invitation NCT00357071

Search NIH Clinical Center for Scleritis

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: scleritis

Genetic Tests for Scleritis

Anatomical Context for Scleritis

MalaCards organs/tissues related to Scleritis:

39
Eye, Neutrophil, Thyroid, T Cells, Testes, Bone, Endothelial

Publications for Scleritis

Articles related to Scleritis:

(show top 50) (show all 610)
id Title Authors Year
1
Scleritis Associated with SAPHO Syndrome: A Case Report. ( 28060551 )
2017
2
Successful treatment with tocilizumab for refractory scleritis associated with relapsing polychondritis. ( 28120637 )
2017
3
Necrotizing scleritis after pterygium excision with fibrin glue-fixated conjunctival autograft in Behcet's disease. ( 27521677 )
2016
4
Isolated posterior scleritis associated with tuberculosis. ( 27224075 )
2016
5
Posterior Scleritis and Necrobiotic Xanthogranuloma. ( 26717063 )
2016
6
A Rare Patient With Orbital Apex Syndrome, Anterior Uveitis, and Necrotizing Scleritis Due to Herpes Zoster Ophthalmicus. ( 28005810 )
2016
7
Assessment of the Accuracy of Using ICD-9 Codes to Identify Uveitis, Herpes Zoster Ophthalmicus, Scleritis, and Episcleritis. ( 27387135 )
2016
8
Latent tuberculosis-related scleritis: a case report. ( 27646473 )
2016
9
Intravitreal dexamethasone implants for the treatment of refractory scleritis combined with uveitis in adult-onset Still's disease: a case report. ( 27825329 )
2016
10
Infectious Pseudomonas and Bipolaris scleritis following history of pterygium surgery. ( 27853018 )
2016
11
Rituximab in the Treatment of Refractory Noninfectious Scleritis. ( 27161988 )
2016
12
Uveitis Specialists and Rheumatologists Select Different Therapies for Idiopathic Non-necrotizing Anterior Scleritis. ( 27744531 )
2016
13
Scleritis associated with relapsing polychondritis. ( 26888976 )
2016
14
Refractory necrotizing scleritis successfully treated with adalimumab. ( 27734292 )
2016
15
Bilateral Scleritis and Retinal Vasculitis in Microscopic Polyangiitis. ( 27871395 )
2016
16
ACANTHAMOEBA ENDOPHTHALMITIS AFTER RECURRENT KERATITIS AND NODULAR SCLERITIS. ( 27152698 )
2016
17
Trabecular Micro-Bypass Stent Use in Necrotizing Scleritis. ( 27977475 )
2016
18
Interleukin-22 serum levels are elevated in active scleritis. ( 27009382 )
2016
19
Aspergillus fumigatus Endophthalmitis with Necrotizing Scleritis following Pars Plana Vitrectomy. ( 27379189 )
2016
20
Poststreptococcal syndrome presenting as posterior scleritis in a child. ( 28007653 )
2016
21
Rituximab in the Treatment of Refractory Noninfectious Scleritis. ( 26766304 )
2016
22
Rheumatoid polyarthritis suspected in an HIV patient with scleritis, peripheral ulcerative keratitis, and anterior uveitis. ( 26893583 )
2016
23
An unusual case of ocular tuberculosis presenting as subretinal abscess with posterior scleritis. ( 27193122 )
2016
24
Surgical treatment of peripheral ulcerative keratitis and necrotizing scleritis in granulomatosis with polyangiitis. ( 26837405 )
2016
25
Local treatment for scleritis secondary to Wiskott-Aldrich syndrome. ( 26951873 )
2016
26
Mycobacterium abscessus scleritis after a Baerveldt glaucoma implant. ( 27552708 )
2016
27
Clinical Features and Complications of Scleritis in Chinese Patients. ( 27849414 )
2016
28
Invasive Ocular Surface Squamous Neoplasia Masquerading as Nodular Scleritis. ( 27262144 )
2016
29
Scleritis with Devastating Consequences. ( 27772649 )
2016
30
Clinical Profile of Patients with Necrotizing Scleritis in a Tertiary Eye Care Center in Southern India. ( 27762661 )
2016
31
Management of necrotizing scleritis after pterygium surgery with rituximab. ( 27982218 )
2016
32
Posterior scleritis in pediatric age group: A case report and review of literature. ( 27013832 )
2016
33
Scleritis Due to Histoplasmosis. ( 26764883 )
2016
34
Multifocal Surgically Induced Necrotizing Scleritis Following Strabismus Surgery: A Case Report. ( 27485819 )
2016
35
Posterior scleritis presenting as conjunctivitis in a child. ( 27941114 )
2016
36
CT and MR Imaging in the Diagnosis of Scleritis. ( 27444937 )
2016
37
Diagnosis and management of non-infectious immune-mediated scleritis: current status and future prospects. ( 27055583 )
2016
38
A Case of Necrobiotic Xanthogranuloma Presenting as Bilateral Posterior Scleritis. ( 27775456 )
2016
39
Gevokizumab in the treatment of autoimmune, non-necrotizing, anterior scleritis: Results of a phase I/II clinical trial. ( 27663070 )
2016
40
Scleritis. ( 26872551 )
2016
41
Trigeminal autonomic cephalgia caused by recurrent posterior scleritis. ( 27495133 )
2016
42
Rituximab in the Treatment of Refractory Noninfectious Scleritis. ( 27138731 )
2016
43
Patterns of Uveitis and Scleritis in Nepal: A Tertiary Referral Center Study. ( 27191731 )
2016
44
Nodular Scleritis Associated with Herpes Zoster Virus: An Infectious and Immune-Mediated Process. ( 27298747 )
2016
45
Nodular scleritis as a presenting feature of Takayasu's arteritis. ( 27221684 )
2016
46
Ocular toxocariasis presenting as bilateral scleritis with suspect retinal granuloma in the nerve fiber layer: a case report. ( 27538451 )
2016
47
Subconjunctival sirolimus in the treatment of autoimmune non-necrotizing anterior scleritis: results of a phase I/II clinical trial. ( 25526946 )
2015
48
Posterior Scleritis with Inflammatory Retinal Detachment. ( 26759674 )
2015
49
Tocilizumab and steroid boli for treatment-resistant anterior necrotizing scleritis. ( 26033325 )
2015
50
Nodular Posterior Scleritis Mimicking Choroidal Tumor in a Patient With Systemic Lupus Erythematous: A Case Report and Literature Review. ( 26692258 )
2015

Variations for Scleritis

Expression for Scleritis

Search GEO for disease gene expression data for Scleritis.

Pathways for Scleritis

Pathways related to Scleritis according to GeneCards Suite gene sharing:

(show all 50)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.39 CCL2 IFNG IL4 IL5 ITGB2 TNF
2
Show member pathways
13.25 CCL2 IL4 IL5 ITGB2 TNF
3
Show member pathways
13.21 CCL2 IFNG IL4 IL5 ITGB2 MMP9
4
Show member pathways
12.78 CCL2 IFNG MMP9 TNF
5
Show member pathways
12.77 CCL2 MMP9 SELE TNF
6
Show member pathways
12.77 IFNG IL4 IL5 ITGB2 TNF
7
Show member pathways
12.68 CCL2 IFNG IL4 TNF
8
Show member pathways
12.5 IFNG IL4 IL5 TNF
9 12.46 CCL2 IFNG IL4 ITGB2 TNF
10
Show member pathways
12.44 IFNG IL4 ITGB2 TNF
11
Show member pathways
12.37 IFNG IL4 IL5 TNF
12
Show member pathways
12.28 CCL2 IFNG IL4 TNF
13
Show member pathways
12.2 IFNG IL4 ITGB2 TNF
14 12.13 IFNG ITGB2 TNF
15
Show member pathways
12.12 IFNG IL4 IL5 TNF
16
Show member pathways
12.11 IFNG IL4 IL5
17
Show member pathways
12.09 IFNG IL4 TNF
18 12.08 IFNG MMP9 TNF
19 11.97 CCL2 IFNG MMP9 SELE TNF
20
Show member pathways
11.97 CCL2 IFNG IL4 IL5 MMP9 TNF
21 11.95 IFNG IL4 IL5 TNF
22 11.91 CCL2 MMP9 SELE TNF
23 11.88 CCL2 IFNG IL4 MMP9 TNF
24 11.84 CCL2 SELE TNF
25 11.83 IL4 IL5 TNF
26 11.82 IFNG ITGB2 TNF
27 11.8 CCL2 IFNG ITGB2 TNF
28 11.78 CCL2 IL4 ITGB2 MMP9 TNF
29 11.75 IFNG IL4 IL5 SELE
30 11.73 IFNG IL4 IL5 TNF
31
Show member pathways
11.69 IFNG IL4 IL5 TNF
32 11.64 IL4 IL5 ITGB2 TNF
33
Show member pathways
11.58 IFNG MMP9 SELE TNF
34 11.51 CCL2 IL4 TNF
35 11.5 ITGB2 MMP9 TNF
36 11.49 IFNG IL4 IL5
37 11.44 CCL2 IFNG ITGB2 TNF
38 11.34 IFNG SELE TNF
39 11.31 IFNG IL4 IL5
40 11.25 CCL2 MMP9
41 11.23 CCL2 MMP9
42 11.19 IFNG IL4 IL5
43 11.17 CCL2 IFNG MMP9
44 11.17 IFNG IL4 IL5 TNF
45 11.15 CCL2 IL4 IL5 TNF
46 11.15 CCL2 IL4 IL5 MMP9 TNF
47 11.03 IFNG IL4 IL5 TNF
48 10.89 CCL2 TNF
49 10.85 IL4 IL5
50 10.71 CCL2 IFNG ITGB2 SELE TNF

GO Terms for Scleritis

Cellular components related to Scleritis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.43 CCL2 IFNG IL4 IL5 MMP9 TNF
2 extracellular space GO:0005615 9.17 CCL2 IFNG IL4 IL5 MMP9 SELE

Biological processes related to Scleritis according to GeneCards Suite gene sharing:

(show all 35)
id Name GO ID Score Top Affiliating Genes
1 positive regulation of transcription, DNA-templated GO:0045893 9.94 IFNG IL4 IL5 TNF
2 extracellular matrix organization GO:0030198 9.83 ITGB2 MMP9 TNF
3 regulation of immune response GO:0050776 9.83 IFNG IL4 ITGB2
4 immune response GO:0006955 9.8 CCL2 IFNG IL4 IL5 TNF
5 leukocyte migration GO:0050900 9.78 ITGB2 MMP9 SELE TNF
6 cellular response to lipopolysaccharide GO:0071222 9.76 CCL2 IFNG TNF
7 positive regulation of sequence-specific DNA binding transcription factor activity GO:0051091 9.74 IL4 IL5 TNF
8 neutrophil chemotaxis GO:0030593 9.71 CCL2 IFNG ITGB2
9 humoral immune response GO:0006959 9.7 CCL2 IFNG TNF
10 protein kinase B signaling GO:0043491 9.67 CCL2 TNF
11 lipopolysaccharide-mediated signaling pathway GO:0031663 9.66 CCL2 TNF
12 protein import into nucleus, translocation GO:0000060 9.65 IFNG TNF
13 response to tumor necrosis factor GO:0034612 9.65 CCL2 SELE
14 endodermal cell differentiation GO:0035987 9.64 ITGB2 MMP9
15 leukocyte cell-cell adhesion GO:0007159 9.63 ITGB2 SELE
16 positive regulation of protein complex assembly GO:0031334 9.63 IFNG TNF
17 positive regulation of cell adhesion GO:0045785 9.63 CCL2 IFNG TNF
18 positive regulation of osteoclast differentiation GO:0045672 9.62 IFNG TNF
19 defense response to protozoan GO:0042832 9.62 IFNG IL4
20 positive regulation of vascular smooth muscle cell proliferation GO:1904707 9.61 MMP9 TNF
21 negative regulation of growth of symbiont in host GO:0044130 9.61 IFNG TNF
22 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.6 IFNG TNF
23 leukocyte tethering or rolling GO:0050901 9.59 SELE TNF
24 positive regulation of podosome assembly GO:0071803 9.58 IL5 TNF
25 positive regulation of isotype switching to IgG isotypes GO:0048304 9.56 IFNG IL4
26 positive regulation of protein phosphorylation GO:0001934 9.56 IFNG IL4 MMP9 TNF
27 positive regulation of MHC class II biosynthetic process GO:0045348 9.55 IFNG IL4
28 inflammatory response GO:0006954 9.55 CCL2 IL5 ITGB2 SELE TNF
29 positive regulation of nitric oxide biosynthetic process GO:0045429 9.54 IFNG ITGB2 TNF
30 positive regulation of mononuclear cell migration GO:0071677 9.51 IL4 TNF
31 cellular extravasation GO:0045123 9.49 ITGB2 TNF
32 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.43 IFNG TNF
33 positive regulation of vitamin D biosynthetic process GO:0060557 9.32 IFNG TNF
34 leukocyte migration involved in inflammatory response GO:0002523 9.13 CCL2 ITGB2 SELE
35 positive regulation of chemokine biosynthetic process GO:0045080 8.8 IFNG IL4 TNF

Molecular functions related to Scleritis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.02 CCL2 IFNG IL4 IL5 TNF

Sources for Scleritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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