MCID: SCL009
MIFTS: 47

Sclerosing Cholangitis malady

Categories: Gastrointestinal diseases, Rare diseases, Liver diseases

Aliases & Classifications for Sclerosing Cholangitis

About this section

Aliases & Descriptions for Sclerosing Cholangitis:

Name: Sclerosing Cholangitis 11 13
Cholangitis, Sclerosing 39 68
 
Primary Sclerosing Cholangitis 68
Fibrosing Cholangitis 11

Classifications:



External Ids:

Disease Ontology11 DOID:14268
ICD1030 K83.0
MeSH39 D015209

Summaries for Sclerosing Cholangitis

About this section
MalaCards based summary: Sclerosing Cholangitis, also known as cholangitis, sclerosing, is related to cholangitis, primary sclerosing and retroperitoneal fibrosis. An important gene associated with Sclerosing Cholangitis is CLDN1 (Claudin 1), and among its related pathways are Drug Induction of Bile Acid Pathway and Etoposide Pathway, Pharmacokinetics/Pharmacodynamics. Affiliated tissues include liver, colon and t cells, and related mouse phenotypes are Increased shRNA abundance (Z-score > 2) and liver/biliary system.

Related Diseases for Sclerosing Cholangitis

About this section

Diseases in the Sclerosing Cholangitis family:

Cholangitis, Primary Sclerosing Secondary Sclerosing Cholangitis

Diseases related to Sclerosing Cholangitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 240)
idRelated DiseaseScoreTop Affiliating Genes
1cholangitis, primary sclerosing33.6BPI, CFTR, MST1
2retroperitoneal fibrosis30.3CD40LG, HLA-DRB1, TNF
3arteriosclerosis29.7CD40LG, MPO
4xanthomatosis29.6CD40LG, HLA-DRB1, TNF
5uveitis29.4BPI, CTSG, MPO
6lymphopenia28.9ALB, CD40LG, CFTR, MPO, TNF
7systemic lupus erythematosus28.6ALB, CD40LG, CTSG, HLA-DRB1, TNF
8ichthyosis, leukocyte vacuoles, alopecia, and sclerosing cholangitis12.4
9secondary sclerosing cholangitis12.4
10igg4-related sclerosing cholangitis12.1
11cholangitis11.1
12cholangiocarcinoma, susceptibility to11.0
13progressive locomotor ataxia10.7HLA-B, HLA-DRB1
14colitis10.6
15ulcerative colitis10.6
16gonococcal iridocyclitis10.6HLA-B, HLA-C
17vitreoretinochoroidopathy dominant10.6HLA-B, HLA-DRB1
18scrub typhus10.6ALB, TNF
19parsonage turner syndrome10.6HLA-DRB1, TNF
20myopathy-growth delay-intellectual disability-hypospadias syndrome10.5HLA-DRB1, TNF
21mitochondrial encephalomyopathy10.5HLA-B, HLA-C, HLA-DRB1
22pancreatitis10.5
23myxoid chondrosarcoma10.5ALB, FUT2, HLA-DRB1
24foster-kennedy syndrome10.5HLA-B, HLA-C, HLA-DRB1
25common variable immunodeficiency10.5HLA-B, HLA-DRB1, TNF
26epstein-barr virus hepatitis10.5HLA-B, HLA-DRB1, TNF
27cirrhotic cardiomyopathy10.5HLA-B, HLA-C, HLA-DRB1
28krieble bixler syndrome10.5CFTR, HLA-DRB1, TNF
29hernia of ovary and fallopian tube10.5HLA-B, HLA-DRB1, TNF
30conjunctival pigmentation10.5HLA-B, HLA-C, HLA-DRB1
31sensorineural hearing loss10.5HLA-B, HLA-DRB1, TNF
32hepatitis10.5
33autoimmune pancreatitis10.5
34panuveitis10.4HLA-C, HLA-DRB1, TNF
35pulmonary systemic sclerosis10.4HLA-B, HLA-DRB1, TNF
36primary biliary cirrhosis10.4
37keratomalacia10.4HLA-B, HLA-C, TNF
38cerebral atrophy10.4MPO, TNF
39hepatic coma10.4ALB, HLA-DRB1, TNF
40orbital periostitis10.4HLA-B, HLA-C, TNF
41cutaneous porphyria10.4ALB, CFTR, TNF
42weber syndrome10.4HLA-DRB1, MPO, TNF
43mandibular cancer10.4ALB, FUT2, TNF
44abdominal chemodectomas with cutaneous angiolipomas10.4HLA-DRB1, MPO, TNF
45autoimmune hepatitis10.4
46aseptic osteitis10.3CFTR, HLA-B, HLA-C, HLA-DRB1
47placenta praevia10.3ALB, MPO
48rhizomelic pseudopolyarthritis10.3HLA-DRB1, TNF
49crohn's disease10.3
50potato nose10.3CFTR, HLA-B, HLA-DRB1, TNF

Graphical network of the top 20 diseases related to Sclerosing Cholangitis:



Diseases related to sclerosing cholangitis

Symptoms & Phenotypes for Sclerosing Cholangitis

About this section

GenomeRNAi Phenotypes related to Sclerosing Cholangitis according to GeneCards Suite gene sharing:

26
idDescriptionGenomeRNAi Source AccessionScoreTop Affiliating Genes
1GR00366-A-3510.0CTSG, HLA-B, HLA-C

MGI Mouse Phenotypes related to Sclerosing Cholangitis according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053707.0ABCB11, ABCB4, ALB, CFTR, CTSG, GPBAR1

Drugs & Therapeutics for Sclerosing Cholangitis

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Drugs for Sclerosing Cholangitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 80)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
VancomycinapprovedPhase 4, Phase 3, Phase 13221404-90-6441141, 14969
Synonyms:
(1S,2R,18R,22S,25R,28R,40S)-22-(2-amino-2-Oxoethyl)-48-[2-O-(3-amino-2,3,6-trideoxy-3-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyloxy]-5,15-dichloro-2,18,32,35,37-pentahydroxy-19-[(N-methyl-D-leucyl)amino]-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2(3,6).2(14,17).1(8,12).1(29,33).0(10,25).0(34,39)]pentaconta-3,5,8(48),9,11,14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylic acid
(2.2Sp,3.5sa,2.6sp)-O(4.2),C(3.4):c(5.4),O(4.6):c(3.5),C(2.7)-tricyclo[N-methyl-D-leucyl-3-chloro-(R)-beta-hydroxy-D-tyrosyl-L-asparaginyl-D-2-(4-{[2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyl]oxy}phenyl)glycyl-D-2-(4-hydroxyphenyl)glycyl-3-chloro-(R)-beta-hydroxy-L-tyrosyl-L-2-(3,5-dihydroxyphenyl)glycine]
1404-90-6
1404-93-9 (hydrochloride)
64685-75-2 (sulfate)
AC1L24VU
AC1L9AMI
AC1Q29OH
BIDD:GT0353
C06689
C66H75Cl2N9O24
CHEBI:28001
CHEMBL262777
CID14969
CID441141
CID5311496
CID6426898
CID6917992
D00212
DB00512
EINECS 215-772-6
HSDB 3262
LMPK14000004
 
LS-161387
Lopac0_001267
MolPort-001-794-649
NCGC00162383-02
Prestwick0_000497
Prestwick1_000497
Prestwick2_000497
SPBio_002314
UNII-6Q205EH1VU
VAN
VANCOMYCIN
Vancocin
Vancocin (TN)
Vancocin HCL
Vancomicina
Vancomicina [INN-Spanish]
Vancomycin
Vancomycin (USP)
Vancomycin HCL
Vancomycin [USAN:INN:BAN]
Vancomycine
Vancomycine [INN-French]
Vancomycinum
Vancomycinum [INN-Latin]
nchembio.350-comp1
2
Prednisoloneapproved, vet_approvedPhase 4115350-24-85755
Synonyms:
(11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione
.DELTA.1-Cortisol
.DELTA.1-Dehydrocortisol
.DELTA.1-Dehydrohydrocortisone
.DELTA.1-Hydrocortisone
.delta.-Cortef
.delta.-Stab
1,2-Dehydrohydrocortisone
1,4-Pregnadiene-11beta,17alpha,21-triol-3,20-dione
1,4-Pregnadiene-3,20-dione-11beta,17alpha,21-triol
1-Dehydrocortisol
1-Dehydrohydrocortisone
3,20-dioxo-11beta,17alpha,21-Trihydroxy-1,4-pregnadiene
46656_FLUKA
46656_RIEDEL
50-24-8
58201-11-9
8056-11-9
AC-1773
AC1L1L2E
Ak-Pred
Ak-Tate
Alphadrol
Articulose-50
BPBio1_000164
BRD-K98039984-001-03-0
BRN 1354103
BSPBio_000148
Bio-0666
Bubbli-Pred
C07369
CCRIS 980
CHEBI:8378
CHEMBL131
CID5755
CO-Hydeltra
CPD000718761
Co-Hydeltra
Codelcortone
Cordrol
Cortalone
Cotogesic
Cotolone
D00472
D011239
DB00860
Decaprednil
Decortin H
Delcortol
Delta F
Delta(1)-dehydrohydrocortisone
Delta-Cortef
Delta-Cortef (TN)
Delta-Ef-Cortelan
Delta-Stab
Delta-stab
Deltacortenol
Deltacortril
Deltacortril Enteric
Deltahydrocortisone
Deltasolone
Deltisilone
Depo-Medrol
Derpo PD
Derpo Pd
Dexa-Cortidelt Hostacortin H
Dexa-Cortidelt hostacortin H
Di Adreson F
Di-Adreson F
Di-Adreson-F
Di-adreson F
DiAdresonF
Dicortol
Donisolone
Dydeltrone
EINECS 200-021-7
Eazolin D
Econopred
Econopred Plus
Erbacort
Erbasona
Estilsona
Fernisolone
Fernisolone P
Fernisolone-P
Flamasone
HMS1568H10
HMS2090J05
HSDB 3385
Hostacortin H
Hydeltra
Hydeltra-Tba
Hydeltrasol
Hydeltrone
Hydrodeltalone
Hydrodeltisone
Hydroretrocortin
Hydroretrocortine
I-Pred
Inflamase Forte
Inflamase Mild
K 1557
Key-Pred
Klismacort
LMST02030179
LS-7669
Lentosone
Lite Pred
M-Predrol
 
MLS001304083
MLS002154250
MLS002207037
Medrol
Medrol Acetate
Metacortandralone
Methylprednisolone Acetate
Meti-Derm
Meticortelone
Metreton
MolPort-002-507-147
NCGC00179649-01
NSC 9120
NSC9120
NSC9900
Neo-Delta-Cortef
Nisolone
Nor-Pred T.B.A.
Ocu-Pred
Ocu-Pred Forte
Ophtho-Tate
Orapred
P0152_SIGMA
P0637
P6004_SIGMA
PRDL
PRED-G
Panafcortelone
Paracortol
Paracotol
Pediapred
Poly-Pred
Precortalon
Precortancyl
Precortilon
Precortisyl
Pred Forte
Pred Mild
Predair
Predair A
Predair Forte
Predalone 50
Predalone T.B.A.
Predate
Predate Tba
Predate-50
Predcor-25
Predcor-50
Predcor-Tba
Predisolone Sodium Phosphate
Predne-Dome
Prednelan
Predni-Dome
Prednicen
Predniliderm
Predniretard
Prednis
Prednisolona
Prednisolona [INN-Spanish]
Prednisolone (JP15/USP/INN)
Prednisolone (anhydrous)
Prednisolone Acetate
Prednisolone Sodium Phosphate
Prednisolone Tebutate
Prednisolone [INN:BAN:JAN]
Prednisolonum
Prednisolonum [INN-Latin]
Predonin
Predonine
Prelone
Prenolone
Prestwick0_000274
Prestwick1_000274
Prestwick2_000274
Prestwick3_000274
Prestwick_404
Rolisone
S1737_Selleck
SAM002264639
SMR000718761
SPBio_002367
Scherisolon
Solone
Steran
Sterane
Sterolone
Supercortisol
UNII-9PHQ9Y1OLM
Ulacort
Ultra Pred
Ultracorten H
Ultracortene H
Ultracortene-H
Ultracortene-Hydrogen
Ultracortene-hydrogen
ZINC03833821
component of Ataraxoid
component of K-Predne-Dome
delta(1)-Cortisol
delta(1)-Dehydrocortisol
delta(1)-Dehydrohydrocortisone
delta(1)-Hydrocortisone
delta(sup 1)-Cortisol
delta(sup 1)-Dehydrocortisol
delta(sup 1)-Dehydrohydrocortisone
delta(sup 1)-Hydrocortisone
delta-dehydrocortisol
delta-dehydrohydrocortisone
delta-hydrocortisone
prednisolone
3
Prednisoneapproved, vet_approvedPhase 4135953-03-25865
Synonyms:
(1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-5,17-dione
(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione
(8xi,9xi,14xi)-17,21-dihydroxypregna-1,4-diene-3,11,20-trione
.delta. E
.delta.(sup1)-Cortisone
.delta.-Cortelan
.delta.-Cortisone
.delta.-Cortone
.delta.-E
.delta.1-Cortisone
.delta.1-Dehydrocortisone
.delta.sone
1,2-Dehydrocortisone
1,4-Pregnadiene-17-alpha,21-diol-3,11,20-trione
1,4-Pregnadiene-17.alpha.,21-diol-3,11,20-trione
1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione
1-Cortisone
1-Dehydrocortisone
17,21-Dihydroxypregna-1,4-diene-3,11,20-trione
17alpha,21-Dihydroxy-1,4-pregnadiene-3,11,20-trione
53-03-2
68-59-7
81552_FLUKA
AC-11112
AC1L1LB2
AC1Q29EZ
ACon0_000082
ACon1_000297
AI3-52939
Adasone
Ancortone
Apo-Prednisone
Apo-prednisone
BPBio1_000323
BRD-K85883481-001-04-2
BSPBio_000293
Betapar
Bicortone
Bio-0649
C07370
C21H26O5
CCRIS 2646
CHEBI:8382
CHEMBL635
CID5865
CPD001227202
Cartancyl
Colisone
Cortan
Cortancyl
Cortidelt
Cotone
DB00635
Dacorten
Dacortin
Decortancyl
Decortin
Decortisyl
Dehydrocortisone
Dekortin
Delcortin
Dellacort
Dellacort A
Delta Cortelan
Delta E
Delta E.
Delta-Cortelan
Delta-Dome
Delta-cortelan
Delta-cortisone
Delta-cortone
Delta-dome
Deltacortene
Deltacortisone
Deltacortone
Deltasone
Deltasone, Liquid Pred, Orasone, Adasone, Deltacortisone,Prednisone
Deltison
Deltisona
Deltisone
Deltra
Di-Adreson
Diadreson
EINECS 200-160-3
Econosone
Encorton
Encortone
Enkortolon
Enkorton
Fernisone
Fiasone
HMS1568O15
HMS2090J13
HSDB 3168
Hostacortin
In-Sone
Incocortyl
 
Juvason
Kortancyl
LMST02030180
LS-1325
Liquid Pred
Lisacort
Lodotra
MEGxm0_000443
MLS001061265
MLS001304073
MLS001335907
MLS001335908
MLS002154191
MLS002207083
Me-Korti
Metacortandracin
Meticorten
Meticorten (Veterinary)
Metrevet (Veterinary)
MolPort-001-740-041
NCGC00090766-01
NCGC00090766-02
NCGC00090766-03
NCI-C04897
NCI60_000008
NSC 10023
NSC10023
Nisona
Nizon
Novoprednisone
Nurison
Orasone
Origen Prednisone
P1276
P6254_SIGMA
PRD
Panafcort
Panasol
Paracort
Parmenison
Pehacort
Precort
Predeltin
Prednicen-M
Prednicorm
Prednicort
Prednicot
Prednidib
Prednilonga
Prednison
Prednisona
Prednisona [INN-Spanish]
Prednisone
Prednisone Intensol
Prednisone [INN:BAN]
Prednisonum
Prednisonum [INN-Latin]
Prednitone
Prednizon
Prednovister
Presone
Prestwick0_000077
Prestwick1_000077
Prestwick2_000077
Prestwick3_000077
Prestwick_405
Pronison
Pronisone
Rectodelt
Retrocortine
S1622_Selleck
SAM002264641
SK-Prednisone
SMR000718760
SMR001227202
SPBio_002214
Servisone
Sone
Sterapred
Supercortil
U 6020
UNII-VB0R961HZT
Ultracorten
Ultracortene
WLN: L E5 B666 CV OV AHTTT&J A1 E1 FV1Q FQ
Winpred
Wojtab
ZINC03875357
Zenadrid
Zenadrid (veterinary)
Zenadrid [veterinary]
delta cortelan
delta(sup 1)-Cortisone
delta(sup 1)-Dehydrocortisone
delta-1-Cortisone
delta-1-Dehydrocortisone
delta-Cortisone
delta-Cortone
4
Leflunomideapproved, investigationalPhase 46775706-12-63899
Synonyms:
210165-51-8
4-Isoxazolecarboxamide, 5-methyl-N-(4-(trifluoromethyl)phenyl
4-isoxazolecarboxamide,5-methyl-N-(4-(trifluoromethyl)phenyl)
5-Methyl-N-(4-(trifluoromethyl)phenyl)-4-isoxazolecarboxamide
5-Methylisoxazole-4-(4-trifluoromethyl)carboxanilide
5-Methylisoxazole-4-(4-trifluoromethylcarboxanilide)
5-Methylisoxazole-4-carboxylic acid (4-trifluoromethyl)anilide
5-methyl-N-[4-(trifluoromethyl)phenyl]-1,2-oxazole-4-carboxamide
5-methyl-N-[4-(trifluoromethyl)phenyl]-4-isoxazolecarboxamide
5-methyl-N-[4-(trifluoromethyl)phenyl]isoxazole-4-carboxamide
75706-12-6
A77 1486
AB00052389
AC-6796
AC1L1GYK
AC1Q2EVA
AKOS000265193
AP-501/42475599
Arava
Arava (TN)
Arava, Leflunomide
Aventis Behring Brand of Leflunomide
Aventis Brand of Leflunomide
Aventis Pharma Brand of Leflunomide
BIDD:PXR0189
BPBio1_000930
BRD-K78692225-001-03-9
BSPBio_000844
C045463
C07905
CAS-75706-12-6
CHEBI:6402
CHEMBL960
CID3899
D00749
DB01097
DivK1c_000916
EU-0100649
HMS1570K06
HMS1922M06
HMS2090O12
HMS502N18
HSDB 7289
HWA 486
HWA-486
Hoechst Brand of Leflunomide
I06-2131
IDI1_000916
KBio1_000916
KBio2_000802
KBio2_003370
KBio2_005938
KBioSS_000802
L 5025
L5025_SIGMA
 
LS-86580
Leflunomid
Leflunomida
Leflunomida [INN-Spanish]
Leflunomide
Leflunomide (JAN/USAN/INN)
Leflunomide [USAN:INN]
Leflunomidum
Leflunomidum [INN-Latin]
Lefunomide
Lefunomide [INN-Spanish]
Lefunomide [Inn-Spanish]
Lopac-L-5025
Lopac0_000649
MLS-0003109.0001
MLS000069648
MLS001076267
MolPort-002-345-613
N-(4'-Trifluoromethylphenyl)-5-methylisoxazole-4-carboxamide
N-(4-trifluoromethyphenyl)-5-methylisoxazole-4-carboxamide
NCGC00015610-01
NCGC00015610-02
NCGC00015610-03
NCGC00015610-07
NCGC00015610-12
NCGC00022625-03
NCGC00022625-04
NCGC00022625-05
NCGC00022625-06
NCGC00022625-07
NCGC00022625-08
NINDS_000916
NSC677411
Prestwick0_000772
Prestwick1_000772
Prestwick2_000772
Prestwick3_000772
Prestwick_87
RS-34821
S1247_Selleck
SMR000058209
SPBio_002783
SPECTRUM1503927
SU 101
SU 101 (pharmaceutical)
SU-101
SU101
Spectrum5_000850
Spectrum_000322
TL8005179
UNII-G162GK9U4W
ZINC00004840
alpha,alpha,alpha-Trifluoro-5-methyl-4-isoxazolecarboxy-P-toluidide
alpha,alpha,alpha-Trifluoro-5-methyl-4-isoxazolecarboxy-p-toluidide
leflunomide
lefunamide
5
Methylprednisoloneapproved, vet_approvedPhase 4115383-43-26741
Synonyms:
(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
(6a,11b)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6α,11β)-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione
.DELTA.1-6.alpha.-Methylhydrocortisone
1-Dehydro-6alpha-methylhydrocortisone
1-dehydro-6alpha-Methylhydrocortisone
1-dehydro-6α-methylhydrocortisone
11-beta,17,21-Trihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione
11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methyl-1,4-pregnadiene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
121673-01-6
4-08-00-03498 (Beilstein Handbook Reference)
46436_FLUKA
46436_RIEDEL
570-35-4
6 Methylprednisolone
6-Methylprednisolone
6-alpha-Methylprednisolone
6.alpha.-Methylprednisolone
6923-42-8
6alpha-Methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione
6alpha-Methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
6alpha-Methylprednisolone
6alpha-methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
83-43-2
AC1L1N7A
Artisone-Wyeth
Artisone-wyeth
BPBio1_000174
BRD-K35240538-001-03-1
BRN 2340300
BSPBio_000158
Besonia
Bio-0658
CHEBI:6888
CHEMBL650
CID6741
CPD000058330
D00407
D008775
DB00959
Depo-Medrol (acetate)
Dopomedrol
EINECS 201-476-4
Esametone
Firmacort
HMS1568H20
HMS2090B13
HSDB 3127
LMST02030178
LS-118498
Lemod
M0639_SIGMA
M1665
MEPRDL
MLS000028541
MLS001148159
MLS002207191
Medesone
Medixon
Medlone 21
 
Medrate
Medrol
Medrol (TN)
Medrol Adt Pak
Medrol Dosepak
Medrol adt pak
Medrol dosepak
Medrol, Solu-Medrol, Medrone, Methylprednisolone
Medrone
Mesopren
Metastab
Methyleneprednisolone
Methylprednisolon
Methylprednisolone
Methylprednisolone (JP15/USP/INN)
Methylprednisolone [USAN:INN:BAN:JAN]
Methylprednisolone, 6-alpha
Methylprednisolonum
Methylprednisolonum [INN-Latin]
Metilbetasone
Metilprednisolona
Metilprednisolona [INN-Spanish]
Metilprednisolone
Metilprednisolone [DCIT]
Metilprednisolone [Dcit]
Metipred
Metrisone
Metrocort
Metysolon
Moderin
MolPort-002-528-554
NCGC00022735-03
NCI60_001657
NSC-19987
NSC19987
Nirypan
Noretona
Predni N Tablinen
Prednol- L
Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy-6alpha-methyl- (8CI)
Prestwick0_000279
Prestwick1_000279
Prestwick2_000279
Prestwick3_000279
Prestwick_622
Promacortine
Reactenol
S1733_Selleck
SAM002589984
SMR000058330
SPBio_002377
Sieropresol
Solomet
Summicort
Suprametil
U 7532
UNII-X4W7ZR7023
Urbason
Urbasone
Wyacort
ZINC03875560
delta(1)-6alpha-Methylhydrocortisone
delta(sup 1)-6-alpha-Methylhydrocortisone
methylprednisolone
methylprenisolone
6ImmunoglobulinsPhase 4, Phase 2, Phase 1, Early Phase 16045
7Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 4, Phase 112767
8Liver ExtractsPhase 4, Phase 3, Phase 2, Phase 13868
9AntibodiesPhase 4, Phase 2, Phase 1, Early Phase 16045
10Bile Acids and SaltsPhase 4, Phase 2, Phase 1102
11HormonesPhase 4, Phase 113979
12Immunoglobulin GPhase 4, Phase 1, Phase 2, Early Phase 1265
13Hormone AntagonistsPhase 4, Phase 112778
14glucocorticoidsPhase 4, Phase 14920
15Anti-Inflammatory AgentsPhase 4, Phase 1, Phase 210355
16Anti-Infective AgentsPhase 4, Phase 3, Phase 2, Phase 121402
17Anti-Bacterial AgentsPhase 4, Phase 3, Phase 2, Phase 110884
18Gastrointestinal AgentsPhase 4, Phase 2, Phase 3, Phase 18109
19Immunosuppressive AgentsPhase 4, Phase 2, Phase 112770
20Antirheumatic AgentsPhase 4, Phase 1, Phase 210627
21Prednisolone hemisuccinatePhase 41153
22Prednisolone phosphatePhase 41153
23Methylprednisolone HemisuccinatePhase 41153
24Prednisolone acetatePhase 41153
25Antineoplastic Agents, HormonalPhase 45407
26Methylprednisolone acetatePhase 41153
27
Ursodeoxycholic acidapproved, investigationalPhase 2, Phase 3, Phase 195128-13-231401
Synonyms:
(3a,5b,7b)-3,7-dihydroxy-cholan-24-oate
(3a,5b,7b)-3,7-dihydroxy-cholan-24-oic acid
(3a,5b,7b)-3,7-dihydroxycholan-24-oic acid
(3alpha,5beta,7beta)-3,7-dihydroxycholan-24-oic acid
(3alpha,5beta,7beta,8xi)-3,7-dihydroxycholan-24-oic acid
(3α,5β,7β)-3,7-dihydroxycholan-24-oic acid
(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
128-13-2
17-beta-(1-Methyl-3-carboxypropyl)etiocholane-3-alpha,7-beta-diol
3 alpha,7 beta-Dihydroxy-5 beta-cholan-24-oic Acid
3,7-Dihydroxycholan-24-oic acid
3-alpha,7-beta-Dihydroxy-5-beta-cholanoic acid
3-alpha,7-beta-Dihydroxycholanic acid
3-alpha,7-beta-Dioxycholanic acid
3a,7b-Dihydroxy-5b-cholan-24-oate
3a,7b-Dihydroxy-5b-cholan-24-oic acid
3alpha,7beta-Dihydroxy-5beta-cholan-24-oic acid
3alpha,7beta-Dihydroxy-5beta-cholanic acid
4-10-00-01604 (Beilstein Handbook Reference)
50809-41-1
5beta-Cholan-24-oic acid-3alpha,7beta-diol
5beta-Cholanic Acid-3alpha,7beta-diol
7-beta-Hydroxylithocholic acid
7beta-Hydroxylithocholic acid
80225-86-1
AB00513977
AC-18919
AC-2081
AC1L1LJH
Acide ursodesoxycholique
Acide ursodesoxycholique [INN-French]
Acido ursodeossicolico
Acido ursodeossicolico [Italian]
Acido ursodeoxicolico
Acido ursodeoxicolico [INN-Spanish]
Acidum ursodeoxycholicum
Acidum ursodeoxycholicum [INN-Latin]
Actigall
Actigall (TN)
Antigall
Arsacol
BB_NC-2372
BPBio1_001052
BRN 3219888
BSPBio_000956
C07880
C24H40O4
CCRIS 5502
CHEBI:9907
CHEMBL1551
CHEMBL73390
CID11516715
CID31401
CPD-10534
CPD000058403
Cholan-24-oic acid, 3,7-dihydroxy-, (3-alpha,5-beta,7-beta)- (9CI)
Cholit-ursan
D00734
DB01586
Delursan
Deoxyursocholic Acid
Destolit
Deursil
Dom-ursodiol c
EINECS 204-879-3
HMS1570P18
 
ISO-URSODEOXYCHOLIC ACID
IU5
LMST04010033
LS-53033
Litursol
Lyeton
MLS000028461
MLS001066373
MolPort-001-794-630
MolPort-005-932-884
NCGC00179363-01
NCI60_028904
NSC 657950
NSC 683769
PHL-ursodiol c
PMS-ursodiol c
Peptarom
Prestwick0_000958
Prestwick1_000958
Prestwick2_000958
Prestwick3_000958
S1643_Selleck
SAM002264653
SMP2_000012
SMR000058403
SPBio_003105
Sodium Ursodeoxycholate
Solutrat
U-9000
U0030
U5127_SIGMA
UDCA
UDCS
UNII-724L30Y2QR
URSODEOXYCHOLIC ACID
UrSO
Urosdesoxycholate
Urosdesoxycholic acid
Urosiol
Ursacholic Acid
Ursacol
Urso
Urso (TN)
Urso 250
Urso DS
Urso Forte
Ursobilin
Ursochol
Ursodamor
Ursodeoxy cholic acid
Ursodeoxycholate
Ursodeoxycholic acid
Ursodeoxycholic acid (JP15/INN)
Ursodeoxycholic acid, UDCA, Ursosan, Ursofalk, Urso Forte, Udiliv, Ursodiol
Ursodeoxycholicacid
Ursodesoxycholic acid
Ursodexycholate
Ursodexycholic Acid
Ursodexycholic acid
Ursodiol
Ursodiol (USP)
Ursodiol [USAN]
Ursofalk
Ursolvan
Ursosan
chenodeoxycholic acid
ursodeoxycholate
ursodiol
28
BezafibrateapprovedPhase 31441859-67-039042
Synonyms:
2-(4-{2-[(4-chlorobenzoyl)amino]ethyl}phenoxy)-2-methylpropanoic acid
2-(P-(2-(P-Chlorobenzamido)ethyl)phenoxy)-2-methylpropionic acid
2-(p-(2-(p-Chlorobenzamido)ethyl)phenoxy)-2-methylpropionic acid
2-[4-(2-[4-Chlorobenzamido]ethyl)- phenoxy]-2-methylpropanoic acid
2-[4-[2-(4-Chlorobenzamido)ethyl]phenoxy]-2-methylpropanoic acid
2-[4-[2-(4-Chlorobenzamido)ethyl]phenoxy]isobutyric Acid
2-[4-[2-[(4-chlorobenzoyl)amino]ethyl]phenoxy]-2-methylpropanoic acid
41859-67-0
AB00052265
AB1004588
AC-6817
AC1L20XS
AC1Q5E4V
AKOS005107743
Azufibrat
Azupharma Brand of Bezafibrate
B3346
B7273_SIGMA
BF-759
BM 15.075
BM 15075
BM-15.075
BM-15075
BM15.075
BPBio1_000589
BRD-K46018455-001-06-0
BRN 4267656
BSPBio_000535
BSPBio_001314
BSPBio_003119
Bayer Brand of Bezafibrate
Befibrat
Befizal
Berlin Chemie Brand of Bezafibrate
Berlin-Chemie Brand of Bezafibrate
Betapharm Brand of Bezafibrate
Beza Lande
Beza Puren
Beza-Lande
Beza-Puren
BezaLande
BezaPuren
Bezabeta
Bezacur
Bezafibrat
Bezafibrat PB
Bezafibrate (JP15/USAN/INN)
Bezafibrate Azupharma Brand
Bezafibrate Bayer Brand
Bezafibrate Berlin-Chemie Brand
Bezafibrate Betapharm Brand
Bezafibrate Cryopharma Brand
Bezafibrate Elfar Brand
Bezafibrate Hennig Brand
Bezafibrate Hexal Brand
Bezafibrate Isis Brand
Bezafibrate Lakeside Brand
Bezafibrate Merckle Brand
Bezafibrate Roche Brand
Bezafibrate Synthelabo Brand
Bezafibrate TAD Brand
Bezafibrate Teva Brand
Bezafibrate [USAN:BAN:INN:JAN]
Bezafibrato
Bezafibrato [INN-Spanish]
Bezafibrato [Spanish]
Bezafibrato [inn-spanish]
Bezafibratum
Bezafibratum [INN-Latin]
Bezafibratum [inn-latin]
Bezafisal
Bezalip
Bezalip Retard
Bezamerck
Bezatol
Bezatol SR
Bezatol SR (TN)
Bezatol sr (tn)
Bio2_000034
Bio2_000514
Boehringer Mannheim Brand of Bezafibrate
C19H20ClNO4
CAS-41859-67-0
CCRIS 9085
CHEBI:47612
 
CHEMBL264374
CID39042
Cedur
Cryopharma Brand of Bezafibrate
D001629
D01366
DB01393
DB08380
Difaterol
DivK1c_000092
EINECS 255-567-9
Elfar Brand of Bezafibrate
Eulitop
HMS1361B16
HMS1569K17
HMS1791B16
HMS1921H16
HMS1989B16
HMS2089F04
HMS2092B12
HMS500E14
Hennig Brand of Bezafibrate
Hexal Brand of Bezafibrate
I06-1311
IDI1_000092
IDI1_033784
Isis Brand of Bezafibrate
KBio1_000092
KBio2_000034
KBio2_001923
KBio2_002602
KBio2_004491
KBio2_005170
KBio2_007059
KBio3_000067
KBio3_000068
KBio3_002619
KBioGR_000034
KBioGR_000669
KBioSS_000034
KBioSS_001923
LO 44
LS-124535
Lakeside Brand of Bezafibrate
Lipox
MLS000028533
MLS001148205
Merckle Brand of Bezafibrate
MolPort-001-738-424
NCGC00016850-01
NCGC00016850-02
NCGC00016850-11
NCGC00023317-03
NCGC00023317-04
NCGC00023317-05
NCGC00023317-06
NCGC00023317-07
NCGC00023317-08
NINDS_000092
PB, Bezafibrat
Prestwick0_000378
Prestwick1_000378
Prestwick2_000378
Prestwick3_000378
Prestwick_724
Reducterol
Regadrin B
Roche Brand of Bezafibrate
SMR000058298
SPBio_000824
SPBio_002456
SPECTRUM1502046
ST51014927
Sklerofibrat
Solibay
Spectrum2_000922
Spectrum3_001500
Spectrum4_000325
Spectrum5_001079
Spectrum5_001967
Spectrum_001443
Synthelabo Brand of Bezafibrate
TAD Brand of Bezafibrate
Teva Brand of Bezafibrate
a-[4-(4-chlorobenzoylaminoethyl)phenoxy]isobutyric acid
bezafibrate
durabezur
29AntimetabolitesPhase 3, Phase 1, Phase 211774
30Cholagogues and CholereticsPhase 2, Phase 3, Phase 1127
31Lipid Regulating AgentsPhase 3, Phase 1, Phase 22702
32Hypolipidemic AgentsPhase 3, Phase 1, Phase 22721
33
rituximabapprovedPhase 1, Phase 21654174722-31-710201696
Synonyms:
AntiCD20
IDEC-102
IDEC-C2B8
 
Ig gamma-1 chain C region
MabThera
Mabthera
Rituxan
rituximab
34
Cladribineapproved, investigationalPhase 2714291-63-820279
Synonyms:
(2R,3S,5R)-5-(6-amino-2-Chloropurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol
(2R,3S,5R)-5-(6-amino-2-chloropurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol
2 Chlorodeoxyadenosine
2'-Deoxy-2-chloroadenosine
2-CdA
2-Chloro-2'-deoxy-beta-adenosine
2-Chloro-2'-deoxyadenosine
2-Chloro-6-amino-9-(2-deoxy-beta-D-erythropentofuranosyl)purine
2-Chlorodeoxyadenosine
2-chloro-6-amino-9-(2-Deoxy-beta-D-erythro-pentofuranosyl)purine
2-chloro-6-amino-9-(2-deoxy-beta-D-erythro-pentofuranosyl)purine
2-chloro-Deoxyadenosine
2-chloro-deoxyadenosine
24757-90-2
2CdA
2ClAdo
4291-63-8
AC-7591
AC1L2FXP
Adenosine, 2-chloro-2'-deoxy
BRN 0624220
C10H12ClN5O3.C3H8
CHEBI:567361
CHEMBL1619
CID20279
CL9
CPD000058553
Chlorodeoxyadenosine
Cladarabine
Cladaribine
Cladribina
Cladribine
Cladribine (JAN/USAN/INN)
Cladribine [USAN:INN:BAN]
Cladribinum
 
CldAdo
D01370
D017338
DB00242
FT-0080707
HMS2052K13
HSDB 7564
LS-15109
Leustat
Leustatin
Leustatin (TN)
Leustatin, 2-chlorodeoxyadenosine, Cladribine
Litak
MLS000028377
MLS000028484
MLS000759397
MLS001077345
MolPort-002-054-532
MolPort-005-935-074
Movectro
Mylinax
NCGC00022567-05
NCGC00164384-01
NSC 105014
NSC 105014-F
NSC-105014
RWJ 26251
RWJ-26251
RWJ-26251-000
S1199_Selleck
SAM001246526
SMR000058553
UNII-47M74X9YT5
ZINC03798064
cladribina
cladribine
cladribinum
35
AldesleukinapprovedPhase 239785898-30-2, 110942-02-4
Synonyms:
125-L-serine-2-133-interleukin 2 (human reduced)
 
Interleukin-2 aldesleukin
Interleukin-2(2-133),125-ser
Recombinant interleukin-2 human
36
FenofibrateapprovedPhase 1, Phase 216949562-28-93339
Synonyms:
2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic acid 1-methylethyl ester
49562-28-9
AB00052196
AC-4227
AC1L1FPK
AKOS005107777
AZU, Fenofibrat
AbZ Brand of Procetofen
Abbott Brand of Procetofen
Aliud Brand of Procetofen
Ankebin
Antara
Antara (TN)
Antara (micronized)
Antara Micronized Procetofen
Anto Brand of Procetofen
Apo Feno Micro
Apo Fenofibrate
Apo-Feno-Micro
Apo-Fenofibrate
Apotex Brand of Procetofen
Azupharma Brand of Procetofen
BIDD:GT0574
BPBio1_000166
BRD-K50388907-001-05-6
BRN 2062462
BSPBio_000150
BSPBio_003162
Bouchara Brand of Procetofen
C07586
C20H21ClO4
CAS-49562-28-9
CCRIS 7282
CHEBI:5001
CHEMBL672
CID3339
CIP-Fenofibrate
CPD000058299
Controlip
D00565
D011345
DB01039
Debat, Fenofibrate
DivK1c_000557
EINECS 256-376-3
EU-0100486
Elasterate
Elasterin
F 6020
F6020_SIGMA
FENOFIBRATE (MICRONIZED)
FNF
Fenobeta
Fenobrate
Fenofanton
Fenofibrat AL
Fenofibrat AZU
Fenofibrat AbZ
Fenofibrat FPh
Fenofibrat Heumann
Fenofibrat Hexal
Fenofibrat Stada
Fenofibrat ratiopharm
Fenofibrat-ratiopharm
Fenofibrate
Fenofibrate (JAN/INN)
Fenofibrate Debat
Fenofibrate IDD-P
Fenofibrate MSD
Fenofibrate [INN:BAN]
Fenofibrato
Fenofibrato [INN-Spanish]
Fenofibratum
Fenofibratum [INN-Latin]
Fenofibric acid
Fenogal
Fenoglide
Fenomax
Fenotard
Finofibrate
Fournier Brand of Procetofen
Fulcro
GNR Pharma Brand of Procetofen
GNR-Pharma Brand of Procetofen
GRS-027
Gate Brand of Procetofen
Gen Fenofibrate
Gen-Fenofibrate
Genpharm Brand of Procetofen
HMS1568H12
HMS1921B17
HMS2090G20
HMS2092B05
HMS501L19
Heumann Brand of Procetofen
Heumann, Fenofibrat
Hexal Brand of Procetofen
Hexal, Fenofibrat
I06-0048
IDI1_000557
Isopropyl (4'-(P-chlorobenzoyl)-2-phenoxy-2-methyl)propionate
Isopropyl 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropionate
Isopropyl 2-(p-(p-chlorobenzoyl)phenoxy)-2-methylpropionate
KBio1_000557
KBio2_001730
KBio2_004298
KBio2_006866
KBio3_002382
KBioGR_000706
KBioSS_001730
Knoll Brand of Procetofen
LCP-Feno
LCP-FenoChol
LF 178
 
LF-178
LF178
LS-121256
Lichtenstein Brand of Procetofen
Lipanthyl
Lipantil
Lipantil (TN)
Liparison
Lipidex
Lipidil
Lipidil Micro
Lipidil Supra
Lipidil Ter
Lipidil-Ter
Lipifen
Lipirex
Lipoclar
Lipofen
Lipofen (TN)
Lipofene
Liposit
Lipsin
Lofibra
Lopac-F-6020
Lopac0_000486
Luxacor
MLS000028515
MLS001148191
MTW Brand of Procetofen
MTW Fenofibrat
MTW-Fenofibrat
Merck dura Brand of Procetofen
Micronized Procetofen, Antara
MolPort-002-887-051
NCGC00015437-01
NCGC00015437-02
NCGC00015437-03
NCGC00015437-06
NCGC00015437-12
NCGC00021475-03
NCGC00021475-04
NCGC00021475-05
NCGC00021475-06
NCGC00021475-07
NCGC00021475-08
NINDS_000557
NSC 281319
NSC281319
Nolipax
Novartis Brand of Procetofen
Novo Fenofibrate
Novo-Fenofibrate
Novopharm Brand of Procetofen
Nu Fenofibrate
Nu Pharm Brand of Procetofen
Nu-Fenofibrate
Nu-Pharm Brand of Procetofen
PMS Fenofibrate Micro
PMS-Fenofibrate Micro
Pharmascience Brand of Procetofen
Pharmavit
Phenofibrate
Prestwick0_000275
Prestwick1_000275
Prestwick2_000275
Prestwick3_000275
Prestwick_217
Procetofen
Procetofen Reliant Brand
Procetofen, Antara Micronized
Procetofene
Proctofene
Protolipan
Q Pharm Brand of Procetofen
Q-Pharm Brand of Procetofen
Reliant Brand of Procetofen
S1794_Selleck
SAM002264613
SMR000058299
SPBio_001380
SPBio_002369
SPECTRUM1501010
ST085313
Schering Plough Brand of Procetofen
Schering-Plough Brand of Procetofen
Secalip
Sedufen
Spectrum2_001390
Spectrum3_001431
Spectrum4_000413
Spectrum5_001479
Spectrum_001250
Stada, Fenofibrat
Stadapharm Brand of Procetofen
Supralip
TL8003296
TRICOR (MICRONIZED)
Tricor
Tricor (TN)
Triglide
Triglide (TN)
Trilipix
UNII-U202363UOS
United Drug Brand of Procetofen
ZINC00584092
betapharm Brand of Procetofen
ct Arzneimittel Brand of Procetofen
ct-Arzneimittel Brand of Procetofen
durafenat
fenofibrat von ct
fenofibrate
fenofibric acid
isopropyl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate
nchembio790-comp24
ratiopharm Brand of Procetofen
37Peripheral Nervous System AgentsPhase 2, Phase 122776
38Nucleic Acid Synthesis InhibitorsPhase 2, Phase 14855
39Antibodies, MonoclonalPhase 23795
402-chloro-3'-deoxyadenosinePhase 232
41Antibiotics, AntitubercularPhase 26972
42Interleukin-2Phase 2553
43MitomycinsPhase 2233
44Analgesics, Non-NarcoticPhase 2, Phase 16260
45Angiogenesis InhibitorsPhase 2, Phase 14143
46Alkylating AgentsPhase 24694
47Anti-Retroviral AgentsPhase 23232
48Anti-HIV AgentsPhase 23100
49Antiviral AgentsPhase 29732
50TAK-652Phase 212

Interventional clinical trials:

(show top 50)    (show all 72)
idNameStatusNCT IDPhase
1Effect and Safety of Oral Vancomycin in Primary Sclerosing Cholangitis PatientsRecruitingNCT02605213Phase 4
2A Pilot Study to Characterize Bile Acid Metabolism and Dysbiosis in Primary Sclerosing CholangitisRecruitingNCT02464020Phase 4
3Lipidomics, Proteomics, Micro RNAs and Volatile Organic CompoundsRecruitingNCT02531607Phase 4
4Leflunomide for Maintenance of Remission in IgG4 Related DiseaseRecruitingNCT02703194Phase 4
5Short-term Stenting Versus Balloon Dilatation for Dominant Strictures in Primary Sclerosing CholangitisUnknown statusNCT01398917Phase 3
6Probiotics in Patients With Primary Sclerosing CholangitisUnknown statusNCT00161148Phase 3
7Trial of High-dose Urso in Primary Sclerosing CholangitisCompletedNCT00059202Phase 2, Phase 3
8Digital SpyGlass Confirmed Common Bile Duct Stones Clearance Without FluoroscopyCompletedNCT02967926Phase 3
9The Effect of Bezafibrate on Cholestatic ItchRecruitingNCT02701166Phase 3
10Primary Sclerosing Cholangitis With Oral Vancomycin by the Study of Its Antimicrobial and Immunomodulating EffectsActive, not recruitingNCT01802073Phase 3
11Phase II Pilot Study of Cladribine (2-Chlorodeoxyadenosine; 2-CdA) for Early Stage Primary Sclerosing CholangitisCompletedNCT00004762Phase 2
12Norursodeoxycholic Acid in the Treatment of Primary Sclerosing CholangitisCompletedNCT01755507Phase 2
13Open Label Study to Evaluate Safety and Efficacy of LUM001 in Patients With Primary Sclerosing CholangitisCompletedNCT02061540Phase 2
14Simtuzumab (GS-6624) in the Prevention of Progression of Liver Fibrosis in Subjects With Primary Sclerosing Cholangitis (PSC)CompletedNCT01672853Phase 2
15Rituximab in IgG4-related Disease: A Phase 1-2 TrialCompletedNCT01584388Phase 1, Phase 2
16Mitomycin C Therapy for Patients With Primary Sclerosing CholangitisRecruitingNCT01688024Phase 2
17PERSEUS: Preliminary Efficacy and Safety of Cenicriviroc in Adult Subjects With Primary Sclerosing CholangitisRecruitingNCT02653625Phase 2
18Fecal Microbiota Transplantation for the Treatment of Primary Sclerosing Cholangitis.RecruitingNCT02424175Phase 1, Phase 2
19A Trial of BTT1023 in Patients With Primary Sclerosing CholangitisRecruitingNCT02239211Phase 2
20Phase 2 Study of NGM282 in Patients With Primary Sclerosing CholangitisRecruitingNCT02704364Phase 2
21Safety, Tolerability, and Efficacy of GS-9674 in Adults With Primary Sclerosing Cholangitis Without CirrhosisRecruitingNCT02943460Phase 2
22Induction of Regulatory t Cells by Low Dose il2 in Autoimmune and Inflammatory DiseasesRecruitingNCT01988506Phase 2
23Obeticholic Acid (OCA) in Primary Sclerosing Cholangitis (PSC)Active, not recruitingNCT02177136Phase 2
24A Study of Oral Hymecromone to Treat Adults With Primary Sclerosing CholangitisNot yet recruitingNCT02780752Phase 1, Phase 2
25A Study Evaluating the Safety and Efficacy of Curcumin in Patients With Primary Sclerosing CholangitisNot yet recruitingNCT02978339Phase 1, Phase 2
26A Single-arm,Phase IIa,Safety and Efficacy Trial of Selected MSCs in the Treatment of Patients With PSC & AiHNot yet recruitingNCT02997878Phase 1, Phase 2
27Thalidomide for the Treatment of Primary Sclerosing Cholangitis (PSC)TerminatedNCT00953615Phase 2
28Fenofibrate for PSCTerminatedNCT01142323Phase 1, Phase 2
29The Value of CT Cholangiography in Primary Sclerosing CholangitisWithdrawnNCT00588458Phase 2
30Pilot Study of Budesonide for Patients With Primary Sclerosing CholangitisUnknown statusNCT00004842Phase 1
31Combination Therapy With Ursodeoxycholic Acid (UDCA) and All-Trans Retinoic Acid (ATRA) for Treatment of Primary Sclerosing CholangitisCompletedNCT01456468Phase 1
32Erlotinib for Chemoprevention in Trisomy 7 Positive Primary Sclerosing Cholangitis (PSC)CompletedNCT00955149Phase 1
33Gastrointestinal Microbiota in Primary Sclerosing Cholangitis and Biliary Atresia With VancomycinCompletedNCT01322386Phase 1
34Minocycline in Primary Sclerosing Cholangitis (PSC)CompletedNCT00630942Phase 1
35A Pilot Study of Vancomycin or Metronidazole in Patients With Primary Sclerosing CholangitisCompletedNCT01085760Phase 1
36Evaluation of DHA for the Treatment of PSCCompletedNCT00325013Phase 1
37A Pilot Study of Xifaxan to Treat Patients With PSCCompletedNCT01695174Phase 1
38Biliary Excretion of Conjugated Bile Acids in Humans Measured by 11C-cholylsarcosine PET/CTCompletedNCT01879735Phase 1
39Optical Frequency Domain Imaging (OFDI) for Biliary Stricture ImagingCompletedNCT01439620Phase 1
40Treating Primary Sclerosing Cholangitis and Biliary Atresia With VancomycinRecruitingNCT02137668Phase 1
41Safety and Efficacy Study of Ursodeoxycholic Acid Therapy in Pediatric Primary Sclerosing CholangitisRecruitingNCT01088607Phase 1
42Genomics of Primary Sclerosing Cholangitis (PSC)RecruitingNCT01161992Phase 1
43Treatment of IgG4-Related Disease With Revlimid and RituximabRecruitingNCT02705638Phase 1
44NPD Measurements in PSC PatientsUnknown statusNCT00476814
45Telomere Length and Other Parameters of Telomere Dysfunction in PSC and ColitisUnknown statusNCT02247622
46Liver Transplantation for Hilar Cholangiocarcinoma in Association With Neoadjuvant Radio- and Chemo-therapyUnknown statusNCT01549795
47Measurement of Fibrinogen in Patients With Systemic Inflammatory Response Syndrome (SIRS), Sepsis or Chronicle Liver Disease on Intensive Care Units (ICU)Unknown statusNCT01169168
48Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral HepatitisUnknown statusNCT00160940
49Cohort Study of IgG4RDUnknown statusNCT01670695Early Phase 1
50Sulfation of Bile Acids as a Biomarker for Hepatobiliary DiseasesUnknown statusNCT01200082

Search NIH Clinical Center for Sclerosing Cholangitis


Cochrane evidence based reviews: cholangitis, sclerosing

Genetic Tests for Sclerosing Cholangitis

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Anatomical Context for Sclerosing Cholangitis

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MalaCards organs/tissues related to Sclerosing Cholangitis:

36
Liver, Colon, T cells, Testes, Thyroid, Pancreas, Neutrophil

Publications for Sclerosing Cholangitis

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Articles related to Sclerosing Cholangitis:

(show top 50)    (show all 924)
idTitleAuthorsYear
1
A novel approach to genome-wide association analysis identifies genetic associations with primary biliary cholangitis and primary sclerosing cholangitis in Polish patients. (28056976)
2017
2
CCBE1 Mutation causing Sclerosing Cholangitis - Expanding the Spectrum of Lymphedema-Cholestasis Syndrome. (28073151)
2017
3
Impact of Crohn's Disease Duration on the Risk of Cholangiocarcinoma in Patients With Primary Sclerosing Cholangitis. (28050039)
2017
4
Biliary tract instillation of a SMAC mimetic induces TRAIL-dependent acute sclerosing cholangitis-like injury in mice. (28055006)
2017
5
Primary biliary cholangitis-primary sclerosing cholangitis in an evolving overlap syndrome: A case report. (28089354)
2017
6
Knockout of the Primary Sclerosing Cholangitis-Risk Gene Fut2 Causes Liver Disease in Mice. (28056490)
2017
7
Updates on primary sclerosing cholangitis. (28079751)
2017
8
Retraction notice to: PS124-Efficacy and Safety of Induction Dosing of Vedolizumab for Reducing Biliary Inflammation in Primary Sclerosing Cholangitis (PSC) in Individuals with Inflammatory Bowel Disease [J Hepatol 64 (2016) S199]. (28042931)
2017
9
IgG4-Related Sclerosing Cholangitis. (27466792)
2016
10
French comment on article: Screening primary sclerosing cholangitis and biliary dysplasia with endoscopic retrograde cholangiography and brush cytology: risk factors for biliary neoplasia. (27115927)
2016
11
Isolated ileitis associated with primary sclerosing cholangitis in three patients with Crohn's disease. (26806276)
2016
12
Outcomes of Liver Retransplantation in Patients with Primary Sclerosing Cholangitis. (28027592)
2016
13
Two cases of immunoglobulin G4-related sclerosing cholangitis in which transabdominal ultrasonography was useful in diagnosis and follow-up observation. (27033871)
2016
14
Secondary sclerosing cholangitis rapidly leading to liver cirrhosis: a possible post-ICU treatment sequel. (26092685)
2016
15
The Microbiome and Primary Sclerosing Cholangitis. (27997974)
2016
16
Primary Sclerosing Cholangitis (28025879)
2016
17
Faecal microbiota profiles as diagnostic biomarkers in primary sclerosing cholangitis. (27216937)
2016
18
Letter: impact of concomitant autoimmune diseases on the outcome of primary sclerosing cholangitis. (27137734)
2016
19
Primary Sclerosing Cholangitis. (27653566)
2016
20
A common genetic variant of fucosyltransferase 2 correlates with serum carcinoembryonic antigen levels and affects cancer screening in patients with primary sclerosing cholangitis. (26966527)
2016
21
Cost utility of ERCP-based modalities for the diagnosis of cholangiocarcinoma in primary sclerosing cholangitis. (27590963)
2016
22
Primary sclerosing cholangitis is characterised by intestinal dysbiosis independent from IBD. (27207975)
2016
23
Impact of Concurrent Non-IBD Immunological Diseases on the Outcome of Primary Sclerosing Cholangitis. (26950311)
2016
24
Clinical course and prognosis of pediatric-onset primary sclerosing cholangitis. (27536366)
2016
25
Genetic Abnormalities in Biliary Brush Samples for Distinguishing Cholangiocarcinoma from Benign Strictures in Primary Sclerosing Cholangitis. (27127503)
2016
26
The Natural History of Primary Sclerosing Cholangitis in Children: A Large Single Center Longitudinal Cohort Study. (27504812)
2016
27
Secondary Sclerosing Cholangitis During Pregnancy. (27622193)
2016
28
Comparison of the multidetector-row computed tomography findings of IgG4-related sclerosing cholangitis and extrahepatic cholangiocarcinoma. (26703117)
2016
29
Greater Biosynthetic Liver Dysfunction in Primary Sclerosing Cholangitis Suggests Co-existent or Impending Cholangiocarcinoma. (27047765)
2016
30
An Update on Cancer Risk and Surveillance in Primary Sclerosing Cholangitis. (28028930)
2016
31
Elevated Serum Bilirubin Level Correlates With the Development of Cholangiocarcinoma, Subsequent Liver Transplantation, and Death in Patients With Primary Sclerosing Cholangitis. (26927495)
2016
32
Secondary sclerosing cholangitis in a critically ill patient. (27190777)
2016
33
Impact of Microbes on the Pathogenesis of Primary Biliary Cirrhosis (PBC) and Primary Sclerosing Cholangitis (PSC). (27834858)
2016
34
IgG4-related Sclerosing Cholangitis with No Biliary Stricture but Severe Thickening of the Bile Duct Wall. (27301508)
2016
35
IBD: A timely diagnosis of primary sclerosing cholangitis in IBD. (27507103)
2016
36
Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease. (27992413)
2016
37
Liver Transplant in Patients With Primary Sclerosing Cholangitis. (27182215)
2016
38
Diagnosis of cholangiocarcinoma in primary sclerosing cholangitis: finding a needle in a haystack. (27115919)
2016
39
Absence of the intestinal microbiota exacerbates hepatobiliary disease in a murine model of primary sclerosing cholangitis. (26044703)
2016
40
Primary Sclerosing Cholangitis. (28002708)
2016
41
Duration of Inflammatory Bowel Disease Is Associated With Increased Risk of Cholangiocarcinoma in Patients With Primary Sclerosing Cholangitis and IBD. (27002801)
2016
42
Primary Sclerosing Cholangitis. (28002707)
2016
43
Primary sclerosing cholangitis in the Swiss Inflammatory Bowel Disease Cohort Study: prevalence, risk factors, and long-term follow-up. (27622999)
2016
44
Sclerosing cholangitis and intracranial lymphoma in a child with classical Wiskott-Aldrich syndrome. (27566838)
2016
45
Impaired Hepatic Adaptation to Chronic Cholestasis induced by Primary Sclerosing Cholangitis. (28008998)
2016
46
Alkaline Phosphatase at Diagnosis of Primary Sclerosing Cholangitis and One Year Later: Evaluation of Prognostic Value. (26945698)
2016
47
The evolution of natural history of primary sclerosing cholangitis. (28030370)
2016
48
Gut and liver T cells of common clonal origin in primary sclerosing cholangitis-inflammatory bowel disease. (27647428)
2016
49
Cholestatic Liver Injury: Care of Patients With Primary Biliary Cholangitis or Primary Sclerosing Cholangitis. (27959300)
2016
50
Long-term follow-up of children and adolescents with primary sclerosing cholangitis and autoimmune sclerosing cholangitis. (27498582)
2016

Variations for Sclerosing Cholangitis

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Expression for genes affiliated with Sclerosing Cholangitis

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Search GEO for disease gene expression data for Sclerosing Cholangitis.

Pathways for genes affiliated with Sclerosing Cholangitis

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GO Terms for genes affiliated with Sclerosing Cholangitis

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Cellular components related to Sclerosing Cholangitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intercellular canaliculusGO:004658110.6ABCB11, ABCB4
2MHC class I protein complexGO:004261210.4HLA-B, HLA-C
3ER to Golgi transport vesicle membraneGO:001250710.2HLA-B, HLA-C, HLA-DRB1
4early endosome membraneGO:003190110.1CFTR, HLA-B, HLA-C
5integral component of lumenal side of endoplasmic reticulum membraneGO:007155610.1HLA-B, HLA-C, HLA-DRB1
6cell surfaceGO:00099868.6CD40LG, CFTR, CTSG, HLA-B, HLA-C, HLA-DRB1
7extracellular spaceGO:00056157.9ALB, BPI, CD40LG, CTSG, MPO, MST1
8extracellular exosomeGO:00700627.4ABCB11, ABCB4, ALB, BPI, CFTR, CTSG
9plasma membraneGO:00058866.7ABCB11, ABCB4, CD40LG, CFTR, CLDN1, CTSG

Biological processes related to Sclerosing Cholangitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independentGO:000248010.3HLA-B, HLA-C
2regulation of immunoglobulin secretionGO:005102310.3CD40LG, TNF
3interferon-gamma-mediated signaling pathwayGO:006033310.1HLA-B, HLA-C, HLA-DRB1
4xenobiotic transportGO:00429089.9ABCB4, NR1I2
5negative regulation of growth of symbiont in hostGO:00441309.8CTSG, MPO, TNF
6transportGO:00068109.4ABCB11, ABCB4, ALB, CFTR

Molecular functions related to Sclerosing Cholangitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1peptide antigen bindingGO:00426059.3HLA-B, HLA-C, HLA-DRB1

Sources for Sclerosing Cholangitis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet