MCID: SCL017
MIFTS: 39

Sclerosing Hemangioma malady

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Summaries for Sclerosing Hemangioma

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Wikipedia:65 Benign fibrous histiocytomas (also known as Dermal dendrocytoma,Dermatofibroma,Fibrous... more...

MalaCards based summary: Sclerosing Hemangioma, also known as cutaneous fibrous histiocytoma, is related to hemangioma and giant cell tumor. An important gene associated with Sclerosing Hemangioma is NKX2-1 (NK2 homeobox 1), and among its related pathways is Immune response Bacterial infections in normal airways. The compounds 2,4-dinitrophenol and whey have been mentioned in the context of this disorder. Affiliated tissues include lung, skin and lymph node.

Aliases & Classifications for Sclerosing Hemangioma

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Sclerosing Hemangioma, Aliases & Descriptions:

Name: Sclerosing Hemangioma 8 10
Cutaneous Fibrous Histiocytoma 62
 
Sclerosing Haemangioma 8


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


External Ids:

Disease Ontology8 DOID:495
SNOMED-CT57 72079004, 134302009

Related Diseases for Sclerosing Hemangioma

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Diseases related to Sclerosing Hemangioma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 71)
idRelated DiseaseScoreTop Affiliating Genes
1hemangioma31.8SFTPB, ACTC1, NKX2-1
2giant cell tumor30.5MUC1, ACTC1
3papillary adenocarcinoma30.5NKX2-1, MUC1
4non-small cell lung carcinoma30.1NKX2-1, SFTPB
5breast cancer29.8NKX2-1, SFTPB, MUC1, ACTC1
6adenocarcinoma29.4AXIN1, NKX2-1, MUC1, ACTC1, SYNM, SFTPB
7pulmonary sclerosing hemangioma11.0
8thyroiditis10.5
9hemangioma of lung10.4
10congenital diaphragmatic hernia10.4SFTPB
11paraganglioma10.4ACTC1
12newborn respiratory distress syndrome10.3SFTPB, NKX2-1
13thymus cancer10.3MUC1, NKX2-1
14large cell carcinoma10.2SFTPB, NKX2-1
15sex cord-gonadal stromal tumor10.2MUC1, NKX2-1
16merkel cell carcinoma10.2NKX2-1, MUC1
17interstitial lung disease10.2NKX2-1, SFTPB
18hepatitis10.2
19fibrous histiocytoma10.2
20familial adenomatous polyposis10.2
21histiocytoma10.2
22endotheliitis10.2
23adenosquamous carcinoma10.2NKX2-1, MUC1
24pulmonary alveolar proteinosis10.2MUC1, SFTPB
25respiratory failure10.2SFTPB, NKX2-1
26spindle cell carcinoma10.2MUC1, ACTC1
27spindle cell sarcoma10.2ACTC1, MUC1
28dermatofibrosarcoma protuberans10.1ACTC1, MUC1
29rhabdoid tumor10.1ACTC1, MUC1
30pulmonary sequestration10.1
31hemangiopericytoma10.1MUC1, ACTC1
32malignant mixed mullerian tumor10.1MUC1, ACTC1
33tubular adenocarcinoma10.1MUC1, ACTC1
34angiosarcoma10.1ACTC1, MUC1
35malignant peripheral nerve sheath tumor10.1ACTC1, MUC1
36teratoma10.1ACTC1, NKX2-1
37lung benign neoplasm10.1NKX2-1, SFTPB
38mucoepidermoid carcinoma10.1MUC1, ACTC1
39neurofibroma10.1ACTC1, MUC1
40pleomorphic adenoma10.1MUC1, ACTC1
41malignant fibroxanthoma10.1MUC1, ACTC1
42colorectal cancer10.1
43fibroma10.1
44lymphangioleiomyomatosis10.1
45cavernous hemangioma10.1
46glomangioma10.1
47lung cancer10.1
48mediastinitis10.1
49melanoma10.1
50neuroendocrine tumor10.1

Graphical network of the top 20 diseases related to Sclerosing Hemangioma:



Diseases related to sclerosing hemangioma

Symptoms for Sclerosing Hemangioma

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Drugs & Therapeutics for Sclerosing Hemangioma

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Drug clinical trials:

Search ClinicalTrials for Sclerosing Hemangioma

Search NIH Clinical Center for Sclerosing Hemangioma

Genetic Tests for Sclerosing Hemangioma

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Anatomical Context for Sclerosing Hemangioma

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MalaCards organs/tissues related to Sclerosing Hemangioma:

32
Lung, Skin, Lymph node, Thyroid, Liver, Endothelial, Kidney, Breast, Tongue, Fetal lung

Animal Models for Sclerosing Hemangioma or affiliated genes

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Publications for Sclerosing Hemangioma

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Articles related to Sclerosing Hemangioma:

(show top 50)    (show all 154)
idTitleAuthorsYear
1
Pulmonary sclerosing hemangioma with lymph node metastasis: A case report and literature review. (24944657)
2014
2
Histogenesis of pulmonary sclerosing hemangioma and significance of P63 expression. (23910931)
2013
3
Pneumocytoma (formerly known as sclerosing hemangioma of the lung): a rare cause of chest pain. (23380035)
2013
4
A hepatic sclerosed hemangioma with significant morphological change over a period of 10 years: a case report. (23714181)
2013
5
A rare tumor of the lung: pulmonary sclerosing hemangioma (pneumocytoma). (23290153)
2013
6
Sclerosing hemangioma of the lung manifesting as a cystic lesion with an air-fluid level. (22832056)
2012
7
Treatment of 28 patients with sclerosing hemangioma (SH) of the lung. (22515818)
2012
8
Pulmonary sclerosing hemangioma: pitfalls in management. (21471259)
2011
9
Comparison of genetic and epigenetic alterations at 11 tumor suppressor loci in pulmonary sclerosing hemangioma and adenocarcinoma. (21649526)
2011
10
A case of pulmonary sclerosing hemangioma surrounded by giant cystic change on high-resolution computed tomography. (20634757)
2011
11
A case of sclerosing hemangioma evaluated with diffusion-weighted magnetic resonance imaging and 18F-fluorodeoxyglucose positron emission tomography. (21057447)
2010
12
Multiple FDG-avid sclerosing hemangiomas mimicking pulmonary metastases in a case of soft tissue sarcoma. (20675249)
2010
13
Sclerosing hemangioma of the lung. (19415961)
2009
14
Respiratory arrest caused by endobronchial sclerosing hemangioma of the left main bronchus. (23168550)
2009
15
Sclerosing hemangioma with an air halo. (19026830)
2008
16
Pulmonary sclerosing hemangioma manifesting as a nodule with irregular air clefts on high-resolution CT. (17579131)
2007
17
Expression of E-cadherin, beta-catenin and p120ctn in the pulmonary sclerosing hemangioma. (17383052)
2007
18
Sclerosing hemangioma of the lung: a benign tumour with potential for malignancy? (17095978)
2006
19
Bilateral multiple pulmonary sclerosing hemangioma. (15828298)
2005
20
Sclerosing hemangioma. (15954523)
2005
21
Sixteen cases of sclerosing hemangioma of the lung including unusual presentations. (15201499)
2004
22
Type-II pneumocyte differentiation in pulmonary sclerosing hemangioma: ultrastructural differentiation and immunohistochemical distribution of lineage-specific transcription factors (TTF-1, HNF-3 alpha, and HNF-3 beta) and surfactant proteins. (15138814)
2004
23
Immunohistochemical and ultrastructural markers suggest different origins for cuboidal and polygonal cells in pulmonary sclerosing hemangioma. (15116333)
2004
24
Pulmonary sclerosing hemangioma with lymph node metastases: report of 4 cases. (12653576)
2003
25
Biologic significance of thyroid transcription factor-1 and surfactant protein expression in pulmonary sclerosing hemangioma]. (14720435)
2003
26
Pulmonary sclerosing hemangioma with lymph node metastases. (14571291)
2003
27
Unilateral progressive multiple sclerosing hemangioma in a young female successfully treated by pneumonectomy: report of a case. (12222919)
2002
28
The expression of thyroid transcription factor-1 in pulmonary sclerosing hemangioma and a further investigation on histogenesis of the tumor]. (11955335)
2002
29
Sclerosing hemangioma of lung: A close cytologic mimicker of pulmonary adenocarcinoma. (11747223)
2001
30
A critical examination of the immunophenotype of pulmonary sclerosing hemangioma. (10716159)
2000
31
Monoclonality of both pale cells and cuboidal cells of sclerosing hemangioma of the lung. (9546367)
1998
32
Pulmonary sclerosing hemangioma in a woman with multiple uterine fibromas, cysts to thyroid and kidney. (8702253)
1996
33
Positive expression of c-myc and p53 products in two cases of pulmonary sclerosing hemangioma]. (8821986)
1995
34
A benign neuroendocrine tumor of the lung: study on the origin of the so-called sclerosing hemangioma of the lung]. (8082241)
1994
35
Sclerosing hemangioma of the lung: pathological study and enzyme immunoassay for estrogen and progesterone receptors. (8237370)
1993
36
Pulmonary sclerosing hemangioma of the lung. A type II pneumocytoma by immunohistochemical and immunoelectron microscopic studies. (2548701)
1989
37
Sclerosing hemangioma of the lung. An immunohistochemical study of intermediate filaments and endothelial markers. (2537067)
1989
38
So-called sclerosing hemangioma of the lung. An immunohistochemical, histochemical and ultrastructural study. (2463730)
1988
39
Sclerosing hemangioma of the lung. An epithelial tumor composed of immunohistochemically heterogenous cells. (2823596)
1987
40
Sclerosing hemangioma of the lung. Immunohistochemical demonstration of mesenchymal origin using antibodies to tissue-specific intermediate filaments. (3021315)
1986
41
Is sclerosing hemangioma of lung an alveolar mixed tumour? (6310472)
1983
42
Pulmonary sclerosing hemangioma: sometimes a form of pulmonary hamartoma. (7089615)
1982
43
Sclerosing hemangioma of the lung: report of a case with an ultrastructural study. (6251145)
1980
44
Case report 104. Sclerosing hemangioma of right seventh rib. (231328)
1979
45
The air meniscus sign in sclerosing hemangioma of the lung. (208101)
1978
46
Sclerosing hemangioma of the tongue: report of case. (1054080)
1975
47
Fibrous histiocytoma of the lung (sclerosing hemangioma variant?). (4362113)
1974
48
Non-neoplastic sclerotic pulmonary lesion (sclerosing hemangioma). Report of a case. (4331028)
1971
49
Sclerosing hemangioma of the lung. (5676973)
1968
50
Sclerosing hemangioma of the lung. (13667023)
1959

Variations for Sclerosing Hemangioma

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Expression for genes affiliated with Sclerosing Hemangioma

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Expression patterns in normal tissues for genes affiliated with Sclerosing Hemangioma

Search GEO for disease gene expression data for Sclerosing Hemangioma.

Pathways for genes affiliated with Sclerosing Hemangioma

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Pathways related to Sclerosing Hemangioma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Transcription NF kB signaling pathway60
Immune response Toll like receptor TLR ligands and common TLR signaling pathway leading to cell proinflammatory response60
9.5MUC1, SFTPA1

Compounds for genes affiliated with Sclerosing Hemangioma

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Compounds related to Sclerosing Hemangioma according to GeneCards/GeneDecks:

(show all 21)
idCompoundScoreTop Affiliating Genes
12,4-dinitrophenol449.9SFTPB, NKX2-1
2whey449.7SFTPB, MUC1
3s 100449.6MUC1, ACTC1
4methanol44 2410.6ACTC1, SFTPB
5reticulin449.6MUC1, ACTC1
6biotin44 24 1111.4MUC1, ACTC1
7gold449.4MUC1, SFTPB
8mucicarmine449.3ACTC1, MUC1, NKX2-1
9b 723449.3ACTC1, MUC1, NKX2-1
10hematoxylin449.3NKX2-1, ACTC1, MUC1
11cyclic amp44 2410.3SFTPB, NKX2-1, MUC1
12formaldehyde44 2410.2ACTC1, MUC1, NKX2-1
13progesterone44 28 61 24 1113.2SFTPB, MUC1, ACTC1
14vegf448.9MUC1, SFTPB, ACTC1
15ribonucleic acid448.8NKX2-1, ACTC1, MUC1, SFTPB
16threonine448.8SFTPB, MUC1, NKX2-1
17paraffin448.8SFTPB, MUC1, ACTC1, NKX2-1
18dexamethasone44 50 28 1111.8MUC1, SFTPB, ACTC1, NKX2-1
19retinoic acid44 249.7SFTPB, MUC1, ACTC1, NKX2-1
20tyrosine448.6ACTC1, MUC1, SFTPB, NKX2-1
21calcium44 50 24 1111.5MUC1, SFTPA1, ACTC1, SFTPB

GO Terms for genes affiliated with Sclerosing Hemangioma

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Biological processes related to Sclerosing Hemangioma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1respiratory gaseous exchangeGO:0075859.6SFTPA1, SFTPB

Products for genes affiliated with Sclerosing Hemangioma

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Sources for Sclerosing Hemangioma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet