MCID: SCT002
MIFTS: 40

Scotoma malady

Eye diseases category

Summaries for Scotoma

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Sources:
66Wikipedia, 34MalaCards
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Wikipedia:66 A scotoma (Greek ??????/sk more...

MalaCards: Scotoma, also known as generalized visual field contraction, is related to constrictive pericarditis and pericarditis. An important gene associated with Scotoma is ABCA4 (ATP-binding cassette, sub-family A (ABC1), member 4), and among its related pathways are Signaling by GPCR and Disease. The compound gtp have been mentioned in the context of this disorder. Affiliated tissues include eye, testes and pituitary, and related mouse phenotype integument.

Aliases & Classifications for Scotoma

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Sources:
9Disease Ontology, 11DISEASES, 63UMLS, 59SNOMED-CT, 28ICD9CM
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Eye diseases


Aliases & Descriptions:

scotoma 9 11 63
generalized visual field contraction 9
arcuate visual field defects 9
blind spot area scotoma nos 9
enlarged paracaecal scotoma 9
scotoma of blind spot area 9
enlarged angioscotoma 9
enlarged blind spot 9
constriction 9
sector 9


External Ids:

Disease Ontology9 DOID:9335
SNOMED-CT59 33970004, 193673000
ICD9CM28 368.44

Related Diseases for Scotoma

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Sources:
18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Scotoma:



Diseases related to scotoma

Symptoms for Scotoma

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Drugs & Therapeutics for Scotoma

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Scotoma

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Genetic Tests for Scotoma

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Anatomical Context for Scotoma

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Sources:
34MalaCards
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MalaCards organs/tissues related to Scotoma:

34
Eye, Testes, Pituitary, Cortex, Brain, Retina, Occipital lobe

Animal Models for Scotoma or affiliated genes

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Sources:
38MGI
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MGI Mouse Phenotypes related to Scotoma:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00107719.0PRL, ABCA4

Publications for Scotoma

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Sources:
53PubMed
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Articles related to Scotoma:

(show top 50)    (show all 188)
idTitleAuthorsYear
1
Parafoveal scotoma progression in glaucoma: humphrey 10-2 versus 24-2 visual field analysis. (23697959)
2013
2
Patient awareness of binocular central scotoma in age-related macular degeneration. (22863789)
2012
3
FUNDUS AUTOFLUORESCENCE IMAGING IN A PATIENT WITH RAPIDLY DEVELOPING SCOTOMA. (23293707)
2012
4
Scotoma displacement in the macular mapping test as a tool for identification of preferred retinal loci. (22333854)
2012
5
Treating our societal scotoma: the case for investing in geriatrics, our nation's future, and our patients. (22547475)
2012
6
Facial pain, scotomas and hemihypaesthesia as presenting symptoms of type A aortic dissection in a patient with migraine with aura. (22407662)
2012
7
Object detection in the ring scotoma of a monocular bioptic telescope. (21555615)
2011
8
Sildenafil improves scotoma after posterior cerebral infarctions: a case report. (20037762)
2010
9
Small effect of interline spacing on maximal reading speed in low-vision patients with central field loss irrespective of scotoma size. (19834038)
2010
10
Scotoma size reduction as an adaptive strategy in age-related macular degeneration. (20648088)
2010
11
Size scaling compensates for sensitivity loss produced by a simulated central scotoma in a shape-from-texture task. (21047750)
2010
12
Microstrabismus: Fixation point scotoma, a perimetric artefact. (19200806)
2009
13
A novel high-resolution kinetic method for visual field mapping of scotoma in age-related macular degeneration. (15497550)
2004
14
Unveiling the foveal blue scotoma through an afterimage. (14659964)
2004
15
Modified astigmatism dial diagram for locating eccentric fixation in patients with central scotoma. (12749291)
2003
16
An unusual junctional scotoma. (12504743)
2002
17
Iatrogenic ring scotoma after laser in situ keratomileusis. (12388042)
2002
18
The effects of simulated cataract on reading with normal vision and simulated central scotoma. (10755163)
1999
19
Compression of the prechiasmatic optic nerve produces a junctional scotoma. (10458197)
1999
20
Effects of cataract and scotoma on visual acuity: a simulation study. (10445638)
1999
21
Residual Vision in Multiple Retinal Locations within a Scotoma: Implications for Blindsight. (23962011)
1997
22
Effectiveness of entoptic perimetry for locating peripheral scotomas caused by cytomegalovirus retinitis. (8660166)
1996
23
Fixation patterns and reading rates in eyes with central scotomas from advanced atrophic age-related macular degeneration and Stargardt disease. (8841306)
1996
24
Responses of cells in monkey visual cortex during perceptual filling-in of an artificial scotoma. (7477262)
1995
25
Scotoma perception in white-noise-field campimetry and postchiasmal visual pathway lesions. (7492935)
1995
26
Resolution of an absolute scotoma after spontaneous disappearance of idiopathic full-thickness macular hole. (8023867)
1994
27
Contrast sensitivity peripheral to an absolute central scotoma in age-related macular degeneration and the influence of a yellow or an orange filter. (8299504)
1993
28
Is there a systematic location for the pseudo-fovea in patients with central scotoma? (8333174)
1993
29
Resolution of an absolute scotoma and improvement of relative scotomata after successful macular hole surgery. (8352296)
1993
30
Effect of a scotoma on eye movements during visual search. (2622676)
1989
31
Increase of the short-term fluctuation of the differential light threshold around a physiologic scotoma. (2596568)
1989
32
The effect of a foveal scotoma on the visual lobe. (3211561)
1988
33
Residual vision in a scotoma. A follow-up study of 'form' discrimination. (3801855)
1987
34
Clinical spatial contrast sensitivity measurement: implications of artificial scotoma experiments. (3953753)
1986
35
Junction scotoma and involvement of the optochiasmal junction. (4010084)
1985
36
Visual field recovery from scotoma in patients with postgeniculate damage. A review of 55 cases. (4005527)
1985
37
Central versus peripheral vision: evaluation of the residual function resulting from a uniocular macular scotoma. (742652)
1978
38
Scotoma due to arterial hypotension. (4800601)
1973
39
The migrainous scintillating scotoma. (5067127)
1972
40
Binocular suppression scotoma: its role in phorias and intermittent tropias. (5425262)
1970
41
Differential diagnosis of the arcuate scotoma. (5763851)
1969
42
Radial peripapillary capillaries of the retina. II. Possible role in Bjerrum scotoma. (5635900)
1968
43
THE BJERRUM SCOTOMA. (14271000)
1965
44
An unusual central scotoma. (13985825)
1962
45
The temporal half-moon: a self-observation in flimmer scotoma. (13217784)
1954
46
Ring Scotoma after Retrobulbar Neuritis. (19993471)
1947
47
Scotoma as a complication of decompression sickness. (20997673)
1946
48
Central Scotoma in Anterior Uveitis: A Further Contribution. (16692615)
1922
49
CENTRAL SCOTOMA IN ANTERIOR UVEITIS. (18168184)
1922
50
BITEMPORAL HEMIOPIA: THE LATER STAGES AND THE SPECIAL FEATURES OF THE SCOTOMA: With an examination of current theories of the mechanism of production of the field defects. (18167670)
1917

Variations for Scotoma

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Expression for genes affiliated with Scotoma

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Scotoma

Search GEO for disease gene expression data for Scotoma.

Pathways for genes affiliated with Scotoma

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51PathCards, 56Reactome
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Pathways related to Scotoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.0PRL, ABCA4
29.0PRL, ABCA4

Compounds for genes affiliated with Scotoma

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46Novoseek, 30IUPHAR
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Compounds related to Scotoma according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1gtp46 3010.3VARS, ABCA4

GO Terms for genes affiliated with Scotoma

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Sources:
17Gene Ontology
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Molecular functions related to Scotoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1ATP bindingGO:0055249.3VARS, ABCA4

Products for genes affiliated with Scotoma

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Scotoma

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet