MCID: SCT002
MIFTS: 42

Scotoma malady

Eye diseases category

Summaries for Scotoma

About this section
Sources:
63Wikipedia, 32MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
Wikipedia:63 A scotoma (Greek σκότος/skótos, darkness; plural: scotomas or scotomata) is an area of partial... more...

MalaCards: Scotoma, also known as generalized visual field contraction, is related to impotence and retinal degeneration. An important gene associated with Scotoma is PRPH (peripherin). The compound gtp have been mentioned in the context of this disorder. Affiliated tissues include eye, testes and pituitary, and related mouse phenotypes are vision/eye and nervous system.

Aliases & Classifications for Scotoma

About this section
Sources:
8Disease Ontology, 10DISEASES, 60UMLS, 56SNOMED-CT, 27ICD9CM
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Eye diseases


Aliases & Descriptions:

scotoma 8 10 60
generalized visual field contraction 8
arcuate visual field defects 8
blind spot area scotoma nos 8
enlarged paracaecal scotoma 8
scotoma of blind spot area 8
enlarged angioscotoma 8
enlarged blind spot 8
constriction 8
sector 8


External Ids:

Disease Ontology8 DOID:9335
SNOMED-CT56 193673000, 33970004
ICD9CM27 368.44

Related Diseases for Scotoma

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Graphical network of the top 20 diseases related to Scotoma:



Diseases related to scotoma

Clinical Features for Scotoma

About this section

Drugs & Therapeutics for Scotoma

About this section
Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Scotoma

Drug clinical trials:

Search ClinicalTrials for Scotoma

Search NIH Clinical Center for Scotoma

Search CenterWatch for Scotoma

Genetic Tests for Scotoma

About this section

Anatomical Context for Scotoma

About this section
Sources:
32MalaCards
See all sources

MalaCards organs/tissues related to Scotoma:

32
Eye, Testes, Pituitary, Cortex, Brain, Retina, Occipital lobe

Animal Models for Scotoma or affiliated genes

About this section
Sources:
36MGI
See all sources

MGI Mouse Phenotypes related to Scotoma:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053918.8ABCA4, PRPF3, GUCY2D, OPA3, UNC119
2MP:00036317.5TECTA, KCNMA1, OPA3, GUCY2D, PRL, PRPH

Publications for Scotoma

About this section
Sources:
50PubMed
See all sources

Articles related to Scotoma:

(show top 50)    (show all 189)
idTitleAuthorsYear
1
Parafoveal scotoma progression in glaucoma: humphrey 10-2 versus 24-2 visual field analysis. (23697959)
2013
2
Central scotoma without prodromal illness caused by Bartonella henselae neuroretinitis. (23481153)
2013
3
Arcuate scotoma associated with traction at the optic disc. (23449516)
2013
4
Scotoma displacement in the macular mapping test as a tool for identification of preferred retinal loci. (22333854)
2012
5
Lack of spatial remapping of the visual field surrounding a monocular scotoma. (21682767)
2012
6
A congruous superior quadrantanopsia following a junctional scotoma induced by asperogillosis. (21860581)
2011
7
Sildenafil improves scotoma after posterior cerebral infarctions: a case report. (20037762)
2010
8
Bilateral central scotoma. (21110511)
2010
9
The relationship between scotoma displacement and preferred retinal loci in low-vision patients with age-related macular degeneration. (20130712)
2010
10
Microstrabismus: Fixation point scotoma, a perimetric artefact. (19200806)
2009
11
The relationship between word length and threshold character size in patients with central scotoma and eccentric fixation. (16163495)
2006
12
Distribution of scotoma pattern related to chiasmal lesions with special reference to anterior junction syndrome. (15069563)
2004
13
Filling-in phenomenon in patients with age-related macular degeneration: differences regarding uni- or bilaterality of central scotoma. (12928905)
2003
14
Iatrogenic ring scotoma after laser in situ keratomileusis. (12388042)
2002
15
Compression of the prechiasmatic optic nerve produces a junctional scotoma. (10970241)
2000
16
Effects of cataract and scotoma on visual acuity: a simulation study. (10445638)
1999
17
Residual Vision in Multiple Retinal Locations within a Scotoma: Implications for Blindsight. (23962011)
1997
18
Object identification without foveal vision: evidence from an artificial scotoma paradigm. (9136264)
1997
19
Perceptual filling-in at the scotoma following a monocular retinal lesion in the monkey. (9057272)
1997
20
Responses of cells in monkey visual cortex during perceptual filling-in of an artificial scotoma. (7477262)
1995
21
Scotoma perception in white-noise-field campimetry and postchiasmal visual pathway lesions. (7492935)
1995
22
Resolution of an absolute scotoma after spontaneous disappearance of idiopathic full-thickness macular hole. (8023867)
1994
23
Effect of a scotoma on eye movements during visual search. (2622676)
1989
24
Residual vision in a scotoma. A follow-up study of 'form' discrimination. (3801855)
1987
25
Recurrent scintillating scotoma and homonymous hemianopia due to metastatic melanoma. (2958508)
1987
26
Scintillating scotoma as the first symptom of systemic lupus erythematosus. (3509277)
1987
27
Bilateral central scotoma with preservation of central vision in 2 patients following caesarean section under spinal anesthesia. (3428103)
1987
28
Reading with a macular scotoma. II. Retinal locus for scanning text. (3610545)
1987
29
The nasal junction scotoma in giant aneurysms. (3763134)
1986
30
Scanning characters and reading with a central scotoma. (4083327)
1985
31
Bridging a neuronal gap. Perceptual completion across a cortical scotoma is dependent on stimulus motion. (4079983)
1985
32
Reduction of body sway by stimuli imaged within a cortical scotoma: a case study. (4008205)
1985
33
Electroretinographic evidence of miosis-induced peripheral ring scotoma. (7116213)
1982
34
Significance of scintillating scotoma of late onset. (7444757)
1980
35
Plasticity in the adult frog brain: filling the visual scotoma after excision or translocation of parts of the optic tectum. (1080068)
1975
36
Shared ethnic scotoma. (4754678)
1973
37
The migrainous scintillating scotoma. (5067127)
1972
38
Migraine equivalent: the scintillating scotoma. (5163773)
1971
39
Etiology and pathogenesis of fixation anomalies in strabismus. IV. Roles of suppression scotoma and of motor factors. (5414004)
1970
40
THE BJERRUM SCOTOMA. (14271000)
1965
41
CENTRAL-PARACENTRAL SCOTOMA AND INTRACRANIAL TUMOUR. (14099420)
1963
42
The migrainous scotoma as studied in 618 persons. (13793037)
1960
43
Scintillating scotoma; clinical and anatomic significance of pattern, size, and movement. (13563182)
1958
44
Pericentral ring scotoma. (15401772)
1950
45
Amblyopia Ex Anopsia. Observations on Retinal Inhibition, Scotoma, Projection, Light Difference Discrimination and Visual Acuity. (16693491)
1948
46
A Scotoma Associated with Menstruation. (16693242)
1940
47
CENTRIPETAL FAN SCOTOMA IN GLAUCOMA. (18168472)
1925
48
BITEMPORAL HEMIOPIA: THE LATER STAGES AND THE SPECIAL FEATURES OF THE SCOTOMA: With an examination of current theories of the mechanism of production of the field defects. (18167666)
1917
49
BITEMPORAL HEMIOPIA: THE LATER STAGES AND THE SPECIAL FEATURES OF THE SCOTOMA: With an examination of current theories of the mechanism of production of the field defects. (18167674)
1917
50
Retrobulbar Neuritis with Central Scotoma from Toxic Action of Thyroidin. (16692386)
1916

Genetic Variations for Scotoma

About this section

Expression for genes affiliated with Scotoma

About this section
Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Scotoma

Search GEO for disease gene expression data for Scotoma.

Pathways for genes affiliated with Scotoma

About this section

Compounds for genes affiliated with Scotoma

About this section
Sources:
44Novoseek, 28IUPHAR
See all sources

Compounds related to Scotoma according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1gtp44 289.7ABCA4, VARS, GUCY2D, KCNMA1

GO Terms for genes affiliated with Scotoma

About this section
Sources:
16Gene Ontology
See all sources

Cellular components related to Scotoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1photoreceptor disc membraneGO:0973819.8ABCA4, GUCY2D

Biological processes related to Scotoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1visual perceptionGO:0076019.2ABCA4, GUCY2D, OPA3, UNC119

Products for genes affiliated with Scotoma

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Scotoma

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet