Aliases & Classifications for Scrapie

About this section

Aliases & Descriptions for Scrapie:

Name: Scrapie 10 47 12 36 65

Classifications:



External Ids:

Disease Ontology10 DOID:5434
SNOMED-CT59 35103004
MeSH36 D012608
UMLS65 C0036457

Summaries for Scrapie

About this section
Wikipedia:68 Scrapie is a fatal, degenerative disease that affects the nervous systems of sheep and goats. It is one... more...

MalaCards based summary: Scrapie is related to personality disorder and atopic dermatitis. An important gene associated with Scrapie is PRNP (Prion Protein), and among its related pathways are Glypican 1 network and A-beta Pathways: Plaque Formation and APP Metabolism. Affiliated tissues include breast, neutrophil and brain, and related mouse phenotypes are growth/size/body region and nervous system.

Related Diseases for Scrapie

About this section

Graphical network of the top 20 diseases related to Scrapie:



Diseases related to scrapie

Symptoms for Scrapie

About this section

Drugs & Therapeutics for Scrapie

About this section

Interventional clinical trials:

idNameStatusNCT IDPhase
1Cohort of Respiratory Failure Patients Treated for the First Time With Non-Invasive Ventilation at HomeRecruitingNCT02346305

Search NIH Clinical Center for Scrapie


Cochrane evidence based reviews: scrapie

Genetic Tests for Scrapie

About this section

Anatomical Context for Scrapie

About this section

MalaCards organs/tissues related to Scrapie:

33
Breast, Neutrophil, Brain, Lung, Prostate, Endothelial, Thyroid

Animal Models for Scrapie or affiliated genes

About this section

MGI Mouse Phenotypes related to Scrapie:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053787.4ADAM10, APP, GFAP, MAP2, PRNP, RPSA
2MP:00036317.1ADAM10, APP, CLU, GFAP, MAP2, PRND

Publications for Scrapie

About this section

Articles related to Scrapie:

(show top 50)    (show all 660)
idTitleAuthorsYear
1
Presence of virulent newcastle disease virus in vaccinated chickens in farms in pakistan. (25694525)
2015
2
Immunolocalization of the 29 kDa Schistosoma haematobium species-specific antigen: a potential diagnostic marker for urinary schistosomiasis. (25927905)
2015
3
VEGF165 modulates proliferation, adhesion, migration and differentiation of cultured human outer root sheath cells from central hair follicle epithelium through VEGFR-2 activation in vitro. (24296159)
2014
4
A new corrective technique for adolescent idiopathic scoliosis (Ucar's convex rod rotation). (25336832)
2014
5
CD99 Expression in Dermatofibrosarcoma Protuberans and Dermatofibroma. (24247571)
2013
6
A misleading urethral smear with polymorphonuclear leucocytes and intracellular diplococci; case report of urethritis caused by Neisseria meningitidis. (24000224)
2013
7
Bovine papular stomatitis affecting dairy cows and milkers in midwestern Brazil. (22362531)
2012
8
Involvement of S100A14 protein in cell invasion by affecting expression and function of matrix metalloproteinase (MMP)-2 via p53- dependent transcriptional regulation. (22451655)
2012
9
Genetic determinants of uveal melanoma. (22042019)
2012
10
Head injury or head motion? Assessment and quantification of motion artifacts in diffusion tensor imaging studies. (21391258)
2012
11
Mass spectrometric characterization of human N-acylethanolamine- hydrolyzing acid amidase. (22040171)
2012
12
Cervical spine trauma in diffuse idiopathic skeletal hyperostosis: injury characteristics and outcome with surgical treatment. (22543253)
2012
13
Cyst fluid interleukin-1beta (IL1beta) levels predict the risk of carcinoma in intraductal papillary mucinous neoplasms of the pancreas. (21266527)
2011
14
Prenatal diagnosis of Comel-Netherton syndrome with PGD, case report and review article. (21573681)
2011
15
Sca-1 influences the innate immune response during skeletal muscle regeneration. (21123737)
2011
16
Nef performance in macrophages: the master orchestrator of viral persistence and spread. (22103834)
2011
17
Gingival angiosarcoma mimicking necrotizing gingivitis. (20359867)
2010
18
Mechanisms regulating invasiveness and growth of endometriosis lesions in rat experimental model and in humans. (20056200)
2010
19
PCNA and MutLI+: partners in crime in triplet repeat expansion? (20823236)
2010
20
Toxic epidermal necrolysis in pregnancy: case report and review of the literature. (20671561)
2010
21
Overexpression of septin 7 suppresses glioma cell growth. (20035367)
2010
22
New vaccines for Japanese encephalitis. (21308526)
2010
23
Myoglobinuria after laparoscopic radiofrequency ablation of liver tumors. (20033345)
2010
24
Hidden high-grade vesicoureteral reflux is the main risk factor for chronic renal damage in children under the age of two years with first urinary tract infection. (19968584)
2009
25
Simvastatin suppresses homocysteine-induced apoptosis in endothelial cells: roles of caspase-3, cIAP-1 and cIAP-2. (19343037)
2009
26
Kinetics of eosinophilia and IgE production in experimental murine toxocariasis. (19143120)
2008
27
Glucose, insulin, and leptin signaling pathways modulate nitric oxide synthesis in glucose-inhibited neurons in the ventromedial hypothalamus. (17170237)
2007
28
Early diagnosis of thyrotoxic periodic paralysis: spot urine calcium to phosphate ratio. (16971853)
2006
29
Functional and molecular identification of sodium-coupled dicarboxylate transporters in rat primary cultured cerebrocortical astrocytes and neurons. (16524379)
2006
30
Mechanisms of the Anti-Ischemic Effect of Angiotensin II AT( 1 ) Receptor Antagonists in the Brain. (16636899)
2006
31
Impact of selective laser ablation of placental anastomoses on the cardiovascular pathology of the recipient twin in severe twin-twin transfusion syndrome. (16777050)
2006
32
Curcumin sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through reactive oxygen species-mediated upregulation of death receptor 5 (DR5). (15987718)
2005
33
HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor. (15916966)
2005
34
Expression in murine teratocarcinoma F9 cells of transcription factors involved in pancreas development. (15194401)
2004
35
Myostatin mutation associated with gross muscle hypertrophy in a child. (15215484)
2004
36
Cheilitis glandularis: an unusual histopathologic presentation. (12627102)
2003
37
Visualizing human leukocyte antigen class II risk haplotypes in human systemic lupus erythematosus. (12145745)
2002
38
Structure of human thymidylate synthase suggests advantages of chemotherapy with noncompetitive inhibitors. (11278511)
2001
39
Conformational plasticity revealed by the cocrystal structure of NKG2D and its class I MHC-like ligand ULBP3. (11754823)
2001
40
Agonist-induced functional desensitization of recombinant human 5-HT2 receptors expressed in CHO-K1 cells. (11448452)
2001
41
Neuron-specific enolase in hemophagocytic lymphohistiocytosis: a potential indicator for macrophage activation? (10979210)
2000
42
Topography of amphiregulin expression in cultured human keratinocytes: colocalization with the epidermal growth factor receptor and CD44. (9542658)
1998
43
Role of epidermal growth factor receptor family members in growth and differentiation of breast carcinoma. (9513724)
1998
44
A prospective, randomized, double-blind multicenter trial of a single bolus injection of the novel modified t-PA E6010 in the treatment of acute myocardial infarction: comparison with native t-PA. E6010 Study Group. (9180103)
1997
45
Use of granulocyte-macrophage colony-stimulating factor (GM-CSF) in combination with hydroxyurea as post-transplant therapy in chronic myelogenous leukemia patients autografted with unmanipulated hematopoietic cells. (9234574)
1997
46
Human cutaneous dendritic cells migrate through dermal lymphatic vessels in a skin organ culture model. (8752673)
1996
47
Prolapsing single orthotopic ureterocele in a boy: case report. (682261)
1978
48
Interstitial abdominal emphysema (pneumatosis cystoides intestinalis). (18730100)
1968
49
Further experiences with the treatment of imperforate anus. (13625023)
1958
50

Variations for Scrapie

About this section

Expression for genes affiliated with Scrapie

About this section
Search GEO for disease gene expression data for Scrapie.

Pathways for genes affiliated with Scrapie

About this section

Pathways related to Scrapie according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.8APP, PRNP
29.7ADAM10, APP
39.7ADAM10, APP
49.3MT2A, TF

GO Terms for genes affiliated with Scrapie

About this section

Cellular components related to Scrapie according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1recycling endosomeGO:00550379.2LDLRAP1, TF
2cell surfaceGO:00099869.2ADAM10, PRNP, TF

Biological processes related to Scrapie according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cholesterol metabolic processGO:00082039.8APP, LDLRAP1
2extracellular matrix organizationGO:00301989.3ADAM10, APP, GFAP
3platelet degranulationGO:00025768.9CLU, TF

Sources for Scrapie

About this section
2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet