Aliases & Classifications for Scrotal Carcinoma

MalaCards integrated aliases for Scrotal Carcinoma:

Name: Scrotal Carcinoma 12 14 69
Neoplasm of Scrotum 12 69
Scrotum Neoplasm 12 14
Malignant Neoplasm of Scrotum 69
Malignant Tumour of Scrotum 12
Malignant Scrotal Neoplasm 12
Malignant Tumor of Scrotum 12
Carcinoma of Scrotum 12
Scrotum Cancer 12
Scrotal Tumor 12
Scrotal Ca 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3445 DOID:518
ICD10 32 C63.2
ICD9CM 34 187.7

Summaries for Scrotal Carcinoma

MalaCards based summary : Scrotal Carcinoma, also known as neoplasm of scrotum, is related to scrotum squamous cell carcinoma and scrotum basal cell carcinoma, and has symptoms including pain in scrotum An important gene associated with Scrotal Carcinoma is CDKN2B (Cyclin Dependent Kinase Inhibitor 2B), and among its related pathways/superpathways are HTLV-I infection and Cell cycle. The drug Menthol has been mentioned in the context of this disorder. Related phenotype is neoplasm.

Related Diseases for Scrotal Carcinoma

Diseases related to Scrotal Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 142)
# Related Disease Score Top Affiliating Genes
1 scrotum squamous cell carcinoma 11.1
2 scrotum basal cell carcinoma 11.0
3 tenosynovial giant cell tumor 10.5 CDKN2A CDKN2B
4 brain stem astrocytic neoplasm 10.4 CDKN2A TP53
5 squamous cell carcinoma of the oropharynx 10.4 CDKN2A TP53
6 spitz nevus 10.4 CDKN2A TP53
7 keratinizing squamous cell carcinoma 10.4 CDKN2A TP53
8 squamous cell carcinoma of the larynx 10.4 CDKN2A TP53
9 atypical neurofibroma 10.4 CDKN2A CDKN2B
10 bartholin's gland benign neoplasm 10.4 CDKN2A TP53
11 anal squamous cell carcinoma 10.4 CDKN2A TP53
12 vulva squamous cell carcinoma 10.4 CDKN2A TP53
13 nasal cavity adenocarcinoma 10.4 CDKN2A TP53
14 bone squamous cell carcinoma 10.4 CDKN2A TP53
15 megaesophagus 10.4 CDKN2A TP53
16 glycogen-rich clear cell breast carcinoma 10.4 CDKN2A TP53
17 bladder papillary transitional cell neoplasm 10.4 ANO2 TP53
18 urinary tract papillary transitional cell benign neoplasm 10.4 ANO2 TP53
19 oral leukoplakia 10.4 CDKN2A TP53
20 anogenital venereal wart 10.4 CDKN2A TP53
21 balanitis xerotica obliterans 10.4 CDKN2A TP53
22 ewing's family of tumors 10.4 CDKN2A CDKN2B
23 cervix uteri carcinoma in situ 10.4 CDKN2A TP53
24 small cell neuroendocrine carcinoma 10.4 CDKN2A TP53
25 meningeal melanomatosis 10.4 CDKN2A TP53
26 suppressor of tumorigenicity 3 10.4 CDKN2A TP53
27 bladder squamous cell carcinoma 10.4 CDKN2A TP53
28 esophagus adenocarcinoma 10.4 CDKN2A TP53
29 endocervical adenocarcinoma 10.4 CDKN2A TP53
30 small cell sarcoma 10.4 CDKN2A TP53
31 cervix small cell carcinoma 10.4 CDKN2A TP53
32 necrotizing sialometaplasia 10.4 CDKN2A TP53
33 basaloid squamous cell carcinoma 10.4 CDKN2A TP53
34 biliary tract neoplasm 10.3 CDKN2A TP53
35 inverted papilloma 10.3 CDKN2A TP53
36 optic nerve neoplasm 10.3 CDKN2A TP53
37 cellular schwannoma 10.3 CDKN2A TP53
38 vulva cancer 10.3 CDKN2A TP53
39 sarcomatoid squamous cell skin carcinoma 10.3 CD68 TP53
40 pre-malignant neoplasm 10.3 CDKN2A TP53
41 mucinous adenocarcinoma 10.3 CDKN2A TP53
42 melanomatosis 10.3 CD68 CDKN2A
43 lymphohistiocytoid mesothelioma 10.3 CD68 CDKN2A
44 juvenile pilocytic astrocytoma 10.3 CDKN2A TP53
45 embryonal sarcoma 10.3 SERPINA3 TP53
46 barrett's adenocarcinoma 10.3 CDKN2A TP53
47 conjunctival degeneration 10.3 CD68 TP53
48 ischemic fasciitis 10.3 CD68 CDKN2A
49 atypical lipomatous tumor 10.3 CDKN2A HMGA2
50 well-differentiated liposarcoma 10.3 CDKN2A HMGA2

Graphical network of the top 20 diseases related to Scrotal Carcinoma:



Diseases related to Scrotal Carcinoma

Symptoms & Phenotypes for Scrotal Carcinoma

UMLS symptoms related to Scrotal Carcinoma:


pain in scrotum

MGI Mouse Phenotypes related to Scrotal Carcinoma:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 neoplasm MP:0002006 9.02 AFP CDKN2A CDKN2B SMUG1 TP53

Drugs & Therapeutics for Scrotal Carcinoma

Drugs for Scrotal Carcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Menthol Approved 2216-51-5 16666

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Videoscopic Versus Open Inguinal Lymphadenectomy for Cancer Completed NCT01526486

Search NIH Clinical Center for Scrotal Carcinoma

Genetic Tests for Scrotal Carcinoma

Anatomical Context for Scrotal Carcinoma

Publications for Scrotal Carcinoma

Articles related to Scrotal Carcinoma:

# Title Authors Year
1
Emergency endovascular management of the common femoral artery rupture due to radiotherapy for scrotal carcinoma. ( 25610613 )
2015
2
A case report of scrotal carcinoma and review of the literature. ( 22949906 )
2012
3
Scrotal carcinoma. ( 21791720 )
2011
4
Scrotal carcinoma: a reminder of a disappearing occupational disease. ( 21686921 )
2009
5
Verrucous scrotal carcinoma in a patient with hypospadias: is there a possible association? ( 12559309 )
2003
6
Dynamic lymphoscintigraphy for staging scrotal carcinoma. ( 11176424 )
2001
7
Verrucous scrotal carcinoma: a radioresponsive tumor. ( 10524907 )
1999
8
Scrotal carcinoma following prolonged use of crude coal tar ointment. ( 2702411 )
1989
9
A population-based study of survival after scrotal carcinoma. ( 3965115 )
1985
10
Scrotal carcinoma in Connecticut metalworkers: sequel to a study of sinonasal cancer. ( 7102658 )
1982

Variations for Scrotal Carcinoma

Expression for Scrotal Carcinoma

Search GEO for disease gene expression data for Scrotal Carcinoma.

Pathways for Scrotal Carcinoma

GO Terms for Scrotal Carcinoma

Cellular components related to Scrotal Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 senescence-associated heterochromatin focus GO:0035985 8.62 CDKN2A HMGA2

Biological processes related to Scrotal Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell cycle GO:0007049 9.73 CDKN2A CDKN2B HMGA2 TP53
2 cell cycle arrest GO:0007050 9.5 CDKN2A CDKN2B TP53
3 positive regulation of cell cycle arrest GO:0071158 9.4 HMGA2 TP53
4 negative regulation of phosphorylation GO:0042326 9.37 CDKN2A CDKN2B
5 positive regulation of cellular senescence GO:2000774 9.26 CDKN2A HMGA2
6 replicative senescence GO:0090399 9.16 CDKN2A TP53
7 senescence-associated heterochromatin focus assembly GO:0035986 8.96 CDKN2A HMGA2
8 base-excision repair GO:0006284 8.8 HMGA2 SMUG1 TP53

Molecular functions related to Scrotal Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 disordered domain specific binding GO:0097718 8.96 CDKN2A TP53
2 cyclin-dependent protein serine/threonine kinase inhibitor activity GO:0004861 8.62 CDKN2A CDKN2B

Sources for Scrotal Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....