MCID: SBC009
MIFTS: 33

Sebaceous Adenoma malady

Categories: Cancer diseases, Skin diseases, Endocrine diseases

Aliases & Classifications for Sebaceous Adenoma

Aliases & Descriptions for Sebaceous Adenoma:

Name: Sebaceous Adenoma 12 14 69
Skin Appendage Sebaceous Adenoma 12
Adenoma of the Sebaceous Gland 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2648
NCIt 47 C4174
SNOMED-CT 64 78424008
UMLS 69 C1368816

Summaries for Sebaceous Adenoma

MalaCards based summary : Sebaceous Adenoma, also known as skin appendage sebaceous adenoma, is related to adenoma and deafness, autosomal recessive 74. An important gene associated with Sebaceous Adenoma is EGF (Epidermal Growth Factor), and among its related pathways/superpathways are Chks in Checkpoint Regulation and Pathways in cancer. Affiliated tissues include skin and salivary gland, and related phenotypes are digestive/alimentary and integument

Wikipedia : 71 A sebaceous adenoma, a type of adenoma, a cutaneous condition characterized by a slow-growing tumor... more...

Related Diseases for Sebaceous Adenoma

Diseases related to Sebaceous Adenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 58)
id Related Disease Score Top Affiliating Genes
1 adenoma 10.5
2 deafness, autosomal recessive 74 10.1 EGF ESR1
3 esophagus sarcoma 10.1 EGF ESR1
4 her2-receptor positive breast cancer 10.1 EGF ESR1
5 haverhill fever 10.1 EGF ESR1
6 muir-torre syndrome 10.1
7 skin melanoma 10.1 MLH1 MSH2
8 fibrolamellar carcinoma 10.0 MLH1 MSH2
9 familial hypopituitarism 10.0 MLH1 MSH2
10 neurocutaneous melanosis, somatic 10.0 MLH1 MSH2
11 collecting duct carcinoma 10.0 MLH1 MSH2
12 malignant spindle cell melanoma 10.0 MLH1 MSH2
13 plague 10.0 EGF ESR1
14 ideomotor apraxia 10.0 MLH1 MSH2
15 autoimmune autonomic ganglionopathy 10.0 MSH2 MSH6
16 prostatic adenoma 10.0 ESR1 MLH1
17 larynx liposarcoma 10.0 MLH1 MSH2
18 cardiomyopathy, dilated, 1r 10.0 MSH2 MSH6
19 trypanosomiasis 9.9 MLH1 MSH6
20 aorta atresia 9.9 EGF MLH1 MSH2
21 nevoid hypermelanosis, linear and whorled 9.9 EGF ESR1 MLH1
22 congenital symblepharon 9.9 MLH1 MSH2
23 rectum sarcoma 9.9 MLH1 MSH2
24 rhinosporidiosis 9.9 EGF ESR1 MLH1
25 oral squamous cell carcinoma 9.8 MLH1 MSH2
26 large intestine adenoma 9.8 MLH1 MSH2 MSH6
27 neuropathy, distal hereditary motor, type viib 9.8 MLH1 MSH2 MSH6
28 churg-strauss syndrome 9.8 MLH1 MSH2 MSH6
29 cauda equina neoplasm 9.8 MLH1 MSH2 MSH6
30 neurofibromatosis-noonan syndrome 9.8 MLH1 MSH2 MSH6
31 mismatch repair cancer syndrome 9.8 MLH1 MSH2 MSH6
32 neuroretinitis 9.8 MLH1 MSH2 MSH6
33 fibromatosis, gingival, 1 9.8 MLH1 MSH2 MSH6
34 hnrnpa1-related amyotrophic lateral sclerosis 9.7 MLH1 MSH2 MSH6
35 wolffian duct adenoma 9.7 MLH1 MSH2 MSH6
36 skin papilloma 9.7 MLH1 MSH2 MSH6
37 asperger syndrome 9.7 MLH1 MSH2 MSH6
38 autosomal genetic disease 9.7 MLH1 MSH2 MSH6
39 t-cell large granular lymphocyte leukemia 9.7 MLH1 MSH2 MSH6
40 seborrheic dermatitis 9.7 MLH1 MSH2 MSH6
41 hidradenoma 9.7 MLH1 MSH2 MSH6
42 proctitis 9.7 MLH1 MSH2 MSH6
43 chronic lymphocytic leukemia 9.7
44 leukemia 9.7
45 cystic teratoma 9.7
46 glioblastoma multiforme 9.7
47 teratoma 9.7
48 adenosquamous carcinoma 9.7
49 syringocystadenoma papilliferum 9.7
50 conjunctivitis 9.7

Graphical network of the top 20 diseases related to Sebaceous Adenoma:



Diseases related to Sebaceous Adenoma

Symptoms & Phenotypes for Sebaceous Adenoma

MGI Mouse Phenotypes related to Sebaceous Adenoma:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.55 CYLD EGF ESR1 MLH1 MSH2
2 integument MP:0010771 9.43 CYLD EGF ESR1 MLH1 MSH2 MSH6
3 neoplasm MP:0002006 9.02 ESR1 MLH1 MSH2 MSH6 CYLD

Drugs & Therapeutics for Sebaceous Adenoma

Search Clinical Trials , NIH Clinical Center for Sebaceous Adenoma

Genetic Tests for Sebaceous Adenoma

Anatomical Context for Sebaceous Adenoma

MalaCards organs/tissues related to Sebaceous Adenoma:

39
Skin, Salivary Gland

Publications for Sebaceous Adenoma

Articles related to Sebaceous Adenoma:

(show top 50) (show all 51)
id Title Authors Year
1
Sebaceous adenomas in the absence of Muir-Torre syndrome. ( 27769341 )
2016
2
A unique case of isolated sebaceous adenoma of the bulbar conjunctiva. ( 27626151 )
2016
3
Sebaceous adenomas of the eyelid and Muir-Torre Syndrome. ( 25595178 )
2015
4
Sebaceous Adenoma of the Caruncle. ( 26398052 )
2015
5
Sebaceous adenoma: clinics, dermatoscopy, and histopathology. ( 25311786 )
2014
6
Corneal limbal sebaceous adenoma. ( 24556852 )
2014
7
A case of sebaceous adenoma of the eyelid showing excessively rapid growth. ( 23579539 )
2013
8
Metachronous occurrence of colorectal cancer in a muir-torre syndrome patient presenting with recurrent sebaceous adenoma of the eyelid: case report and updated review of the literature. ( 23149194 )
2012
9
Sebaceous adenoma arising within an ovarian mature cystic teratoma in Muir-Torre syndrome. ( 21684182 )
2012
10
A rare case of sebaceous adenoma of the palate, with literature review. ( 21443818 )
2011
11
Treatment of sebaceous adenoma with topical photodynamic therapy. ( 20956668 )
2010
12
Sebaceous adenoma of the submandibular gland: a case report. ( 20032620 )
2009
13
Demodex-associated dermatologic conditions--A coincidence or an etiological correlate. Review with a report of a rare case of sebaceous adenoma. ( 19167837 )
2009
14
Comparative clinicopathological study of intraoral sebaceous hyperplasia and sebaceous adenoma. ( 19101492 )
2009
15
Sebaceous adenoma of the parotid gland: a case report with fine needle aspiration findings and histologic correlation. ( 19697727 )
2009
16
Mucoepidermoid (adenosquamous) carcinoma, trichoblastoma, trichilemmoma, sebaceous adenoma, tumor of follicular infundibulum and syringocystadenoma papilliferum arising within 2 persistent lesions of nevus sebaceous: report of a case. ( 19652586 )
2009
17
Sebaceous adenoma of the parotid gland in a 2-year-old male. ( 17418275 )
2007
18
Sebaceous adenoma of the bulbar conjunctiva in association with glioblastoma multiforme and chronic lymphocytic leukemia. ( 17893552 )
2007
19
Penile sebaceous adenoma. ( 17637371 )
2007
20
Sebaceous adenoma of the parotid gland. ( 16878064 )
2006
21
Sebaceous adenoma of the eyelid in Muir-Torre syndrome. ( 15824235 )
2005
22
Sebaceous adenoma in the retromolar region: report of a case with a review of the English literature. ( 14505629 )
2003
23
Sebaceous adenoma of oral cavity: report of case and comparative proliferation study with sebaceous gland hyperplasia and Fordyce's granules. ( 14629335 )
2003
24
Sebaceous adenoma in the submandibular gland. ( 11870356 )
2002
25
Loss of p21(WAF1) compartmentalisation in sebaceous carcinoma compared with sebaceous hyperplasia and sebaceous adenoma. ( 12354803 )
2002
26
Sebaceous adenoma of the cheek. ( 11755830 )
2002
27
Sebaceous adenomas with atypical immunohistochemical features in the Muir-Torre syndrome [leter]. ( 10233335 )
1999
28
Solitary facial lesion. Sebaceous adenoma in association with Muir-Torre syndrome (MTS). ( 9006382 )
1997
29
Immunohistochemical study on sebaceous adenoma and sebaceous carcinoma arising in parotid gland. ( 21594425 )
1996
30
Sebaceous adenoma of the submandibular gland: a case report. ( 8863311 )
1996
31
Sebaceous adenoma with a cutaneous horn. ( 7560356 )
1995
32
Sebaceous adenoma in the region of the medial canthus causing proptosis. ( 10707724 )
1995
33
Sebaceous adenoma of parotid gland--a rare tumour diagnosed by fine needle aspiration cytology. ( 7880973 )
1994
34
CT of sebaceous adenoma of the parotid gland. ( 7976936 )
1994
35
Sebaceous adenoma in a patient with acquired immunodeficiency syndrome. ( 3355190 )
1988
36
Sebaceous adenoma of the oral mucosa. ( 3469349 )
1987
37
Pathology quiz case 1: Sebaceous adenoma. ( 6849571 )
1983
38
Sebaceous adenoma of the oral cavity. ( 6571741 )
1983
39
Tissue connections in a transplantable virus-producing sebaceous adenoma of the mouse. II. A freeze-fracture study in conjunction with filipin. ( 6277960 )
1982
40
Tissue connections in a transplantable virus-producing sebaceous adenoma of the mouse. ( 7338533 )
1981
41
Sebaceous adenoma of the eyelid and visceral malignancy. ( 4440729 )
1974
42
A SEBACEOUS ADENOMA. HISTOLOGICAL AND CHEMICAL STUDIES. ( 14183145 )
1964
43
A REVIEW ON SEBACEOUS ADENOMA WITH REPORT OF A CASE IN THE EXTERNAL AUDITORY MEATUS. ( 14082064 )
1963
44
Sebaceous adenoma of the submaxillary salivary gland. Report of a case. ( 14011757 )
1963
45
Sebaceous adenoma in a dog. ( 13407925 )
1957
46
Scalp: sebaceous adenoma. ( 13094140 )
1953
47
Diethylstilbestrol in the treatment of senile sebaceous adenoma. ( 14952023 )
1952
48
Sebaceous adenoma; review of the literature and report of a case. ( 18919779 )
1948
49
Senile Sebaceous Adenoma. ( 19991727 )
1938
50
Pringle Type of Sebaceous Adenoma. ( 19990196 )
1935

Variations for Sebaceous Adenoma

Expression for Sebaceous Adenoma

Search GEO for disease gene expression data for Sebaceous Adenoma.

Pathways for Sebaceous Adenoma

Pathways related to Sebaceous Adenoma according to GeneCards Suite gene sharing:

(show all 14)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
12.29 ESR1 MSH2 MSH6
2 12.22 EGF MLH1 MSH2 MSH6
3 12.07 MLH1 MSH2 MSH6
4
Show member pathways
11.81 EGF MLH1 MSH2 MSH6
5 11.77 ESR1 MSH2 MSH6
6
Show member pathways
11.54 MLH1 MSH2 MSH6
7
Show member pathways
11.46 MSH2 MSH6
8 11.34 EGF ESR1
9 11.3 MLH1 MSH2 MSH6
10 11.16 MSH2 MSH6
11 11.14 EGF MLH1 MSH2 MSH6
12
Show member pathways
11.12 MLH1 MSH2
13
Show member pathways
11.06 MLH1 MSH2
14 10.59 MLH1 MSH2 MSH6

GO Terms for Sebaceous Adenoma

Cellular components related to Sebaceous Adenoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 MutSalpha complex GO:0032301 8.62 MSH2 MSH6

Biological processes related to Sebaceous Adenoma according to GeneCards Suite gene sharing:

(show all 15)
id Name GO ID Score Top Affiliating Genes
1 cellular response to DNA damage stimulus GO:0006974 9.72 MLH1 MSH2 MSH6
2 DNA repair GO:0006281 9.71 MLH1 MSH2 MSH6
3 intrinsic apoptotic signaling pathway in response to DNA damage GO:0008630 9.54 MLH1 MSH2 MSH6
4 mammary gland alveolus development GO:0060749 9.52 EGF ESR1
5 determination of adult lifespan GO:0008340 9.51 MSH2 MSH6
6 positive regulation of isotype switching to IgG isotypes GO:0048304 9.49 MLH1 MSH2
7 negative regulation of DNA recombination GO:0045910 9.48 MSH2 MSH6
8 positive regulation of helicase activity GO:0051096 9.46 MSH2 MSH6
9 maintenance of DNA repeat elements GO:0043570 9.43 MSH2 MSH6
10 mismatch repair GO:0006298 9.43 MLH1 MSH2 MSH6
11 positive regulation of isotype switching to IgA isotypes GO:0048298 9.4 MLH1 MSH2
12 isotype switching GO:0045190 9.33 MLH1 MSH2 MSH6
13 somatic recombination of immunoglobulin genes involved in immune response GO:0002204 9.32 MLH1 MSH2
14 somatic hypermutation of immunoglobulin genes GO:0016446 9.13 MLH1 MSH2 MSH6
15 somatic recombination of immunoglobulin gene segments GO:0016447 8.8 MLH1 MSH2 MSH6

Molecular functions related to Sebaceous Adenoma according to GeneCards Suite gene sharing:

(show all 13)
id Name GO ID Score Top Affiliating Genes
1 chromatin binding GO:0003682 9.69 ESR1 MLH1 MSH6
2 protein kinase binding GO:0019901 9.67 CYLD ESR1 MSH2
3 ATPase activity GO:0016887 9.61 MLH1 MSH2 MSH6
4 single-stranded DNA binding GO:0003697 9.52 MLH1 MSH2
5 damaged DNA binding GO:0003684 9.48 MSH2 MSH6
6 ADP binding GO:0043531 9.46 MSH2 MSH6
7 four-way junction DNA binding GO:0000400 9.4 MSH2 MSH6
8 oxidized purine DNA binding GO:0032357 9.37 MSH2 MSH6
9 MutLalpha complex binding GO:0032405 9.32 MSH2 MSH6
10 single guanine insertion binding GO:0032142 9.26 MSH2 MSH6
11 single thymine insertion binding GO:0032143 9.16 MSH2 MSH6
12 mismatched DNA binding GO:0030983 9.13 MLH1 MSH2 MSH6
13 guanine/thymine mispair binding GO:0032137 8.8 MLH1 MSH2 MSH6

Sources for Sebaceous Adenoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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