MCID: SBC009
MIFTS: 34

Sebaceous Adenoma malady

Categories: Cancer diseases, Skin diseases, Endocrine diseases

Aliases & Classifications for Sebaceous Adenoma

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Aliases & Descriptions for Sebaceous Adenoma:

Name: Sebaceous Adenoma 11 13 67
Skin Appendage Sebaceous Adenoma 11
 
Adenoma of the Sebaceous Gland 11

Classifications:



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Disease Ontology11 DOID:2648
SNOMED-CT61 78424008
NCIt44 C4174

Summaries for Sebaceous Adenoma

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Wikipedia:70 A sebaceous adenoma, a type of adenoma, a cutaneous condition characterized by a slow-growing tumor... more...

MalaCards based summary: Sebaceous Adenoma, also known as skin appendage sebaceous adenoma, is related to muir-torre syndrome and adenoma, and has symptoms including leser-trélat sign An important gene associated with Sebaceous Adenoma is ESR1 (Estrogen Receptor 1), and among its related pathways are Regulation of Telomerase and Busulfan Pathway, Pharmacodynamics. Affiliated tissues include skin and salivary gland, and related mouse phenotypes are digestive/alimentary and cellular.

Related Diseases for Sebaceous Adenoma

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Diseases related to Sebaceous Adenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 53)
idRelated DiseaseScoreTop Affiliating Genes
1muir-torre syndrome29.2MLH1, MSH2, MSH6
2adenoma10.5
3retinal dystrophies primarily involving bruch's membrane10.2EGF, ESR1
4progesterone-receptor negative breast cancer10.2EGF, ESR1
5thymus lymphoma10.1EGF, ESR1
6blepharochalasis10.1EGF, ESR1
7pityriasis rosea10.0MLH1, MSH2
8cervical adenomyoma10.0MLH1, MSH2
9colver steer godman syndrome10.0MLH1, MSH2
10hyperaldosteronism10.0MLH1, MSH2
11prostate cancer, hereditary, x-linked 110.0ESR1, MSH2
12periapical granuloma10.0MLH1, MSH2
13nodular degeneration of cornea9.9ESR1, MLH1
14brown-vialetto-van laere syndrome9.9EGF, ESR1
15congenital hypomyelination neuropathy9.9MLH1, MSH2
16acquired amegakaryocytic thrombocytopenia9.8MSH2, MSH6
17sleeping sickness9.7MLH1, MSH6
18lung cancer susceptibility 29.7EGF, ESR1
19angioimmunoblastic lymphadenopathy with dysproteinemia9.7EGF, MLH1, MSH2
20colorectal cancer9.7
21chronic lymphocytic leukemia9.7
22leukemia9.7
23cystic teratoma9.7
24glioblastoma multiforme9.7
25teratoma9.7
26adenosquamous carcinoma9.7
27syringocystadenoma papilliferum9.7
28conjunctivitis9.7
29glioblastoma9.7
30clitoris cancer9.6ESR1, MLH1, MSH2
31prostate embryonal rhabdomyosarcoma9.5MSH2, MSH6
32large intestine adenocarcinoma9.4MLH1, MSH2, MSH6
33neuropathy, distal hereditary motor, type viib9.4MLH1, MSH2, MSH6
34food allergy9.4MLH1, MSH2, MSH6
35hereditary essential tremor 59.4MLH1, MSH2, MSH6
36subependymal glioma9.4MLH1, MSH2, MSH6
37solitary bone cyst9.4MLH1, MSH2, MSH6
38optic papillitis9.4MLH1, MSH2, MSH6
39mismatch repair cancer syndrome9.3MLH1, MSH2, MSH6
40neurofibromatosis-noonan syndrome9.3MLH1, MSH2, MSH6
41arrhythmogenic right ventricular cardiomyopathy9.3MLH1, MSH2, MSH6
42cerebellar disease9.3MLH1, MSH2, MSH6
43tumor predisposition syndrome9.3MLH1, MSH2, MSH6
44in situ carcinoma9.3MLH1, MSH2, MSH6
45y-linked disease9.3MLH1, MSH2, MSH6
46gallbladder papillomatosis9.3MLH1, MSH2, MSH6
47hidrocystoma9.3MLH1, MSH2, MSH6
48trachea sarcoma9.0ESR1, MLH1, MSH2, MSH6
49prostate cancer8.8EGF, ESR1, MSH2, MSH6
50spleen angiosarcoma8.6EGF, ESR1, MLH1, MSH2, MSH6

Graphical network of the top 20 diseases related to Sebaceous Adenoma:



Diseases related to sebaceous adenoma

Symptoms for Sebaceous Adenoma

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UMLS symptoms related to Sebaceous Adenoma:


leser-trélat sign

Drugs & Therapeutics for Sebaceous Adenoma

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Sebaceous Adenoma

Genetic Tests for Sebaceous Adenoma

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Anatomical Context for Sebaceous Adenoma

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MalaCards organs/tissues related to Sebaceous Adenoma:

35
Skin, Salivary gland

Animal Models for Sebaceous Adenoma or affiliated genes

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MGI Mouse Phenotypes related to Sebaceous Adenoma:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053818.7CYLD, EGF, ESR1, MLH1, MSH2
2MP:00053848.4CYLD, ESR1, MLH1, MSH2, MSH6
3MP:00107717.8CYLD, EGF, ESR1, MLH1, MSH2, MSH6
4MP:00020067.6CYLD, ESR1, MLH1, MSH2, MSH6

Publications for Sebaceous Adenoma

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Articles related to Sebaceous Adenoma:

(show top 50)    (show all 51)
idTitleAuthorsYear
1
Sebaceous adenomas in the absence of Muir-Torre syndrome. (27769341)
2016
2
A unique case of isolated sebaceous adenoma of the bulbar conjunctiva. (27626151)
2016
3
Sebaceous adenomas of the eyelid and Muir-Torre Syndrome. (25595178)
2015
4
Sebaceous Adenoma of the Caruncle. (26398052)
2015
5
Corneal limbal sebaceous adenoma. (24556852)
2014
6
Sebaceous adenoma: clinics, dermatoscopy, and histopathology. (25311786)
2014
7
A case of sebaceous adenoma of the eyelid showing excessively rapid growth. (23579539)
2013
8
Metachronous occurrence of colorectal cancer in a muir-torre syndrome patient presenting with recurrent sebaceous adenoma of the eyelid: case report and updated review of the literature. (23149194)
2012
9
Sebaceous adenoma arising within an ovarian mature cystic teratoma in Muir-Torre syndrome. (21684182)
2012
10
A rare case of sebaceous adenoma of the palate, with literature review. (21443818)
2011
11
Treatment of sebaceous adenoma with topical photodynamic therapy. (20956668)
2010
12
Sebaceous adenoma of the submandibular gland: a case report. (20032620)
2009
13
Mucoepidermoid (adenosquamous) carcinoma, trichoblastoma, trichilemmoma, sebaceous adenoma, tumor of follicular infundibulum and syringocystadenoma papilliferum arising within 2 persistent lesions of nevus sebaceous: report of a case. (19652586)
2009
14
Demodex-associated dermatologic conditions--A coincidence or an etiological correlate. Review with a report of a rare case of sebaceous adenoma. (19167837)
2009
15
Comparative clinicopathological study of intraoral sebaceous hyperplasia and sebaceous adenoma. (19101492)
2009
16
Sebaceous adenoma of the parotid gland: a case report with fine needle aspiration findings and histologic correlation. (19697727)
2009
17
Sebaceous adenoma of the parotid gland in a 2-year-old male. (17418275)
2007
18
Sebaceous adenoma of the bulbar conjunctiva in association with glioblastoma multiforme and chronic lymphocytic leukemia. (17893552)
2007
19
Penile sebaceous adenoma. (17637371)
2007
20
Sebaceous adenoma of the parotid gland. (16878064)
2006
21
Sebaceous adenoma in the retromolar region: report of a case with a review of the English literature. (14505629)
2003
22
Sebaceous adenoma of oral cavity: report of case and comparative proliferation study with sebaceous gland hyperplasia and Fordyce's granules. (14629335)
2003
23
Loss of p21(WAF1) compartmentalisation in sebaceous carcinoma compared with sebaceous hyperplasia and sebaceous adenoma. (12354803)
2002
24
Sebaceous adenoma in the submandibular gland. (11870356)
2002
25
Sebaceous adenoma of the cheek. (11755830)
2002
26
Sebaceous adenomas with atypical immunohistochemical features in the Muir-Torre syndrome [leter]. (10233335)
1999
27
Solitary facial lesion. Sebaceous adenoma in association with Muir-Torre syndrome (MTS). (9006382)
1997
28
Immunohistochemical study on sebaceous adenoma and sebaceous carcinoma arising in parotid gland. (21594425)
1996
29
Sebaceous adenoma of the submandibular gland: a case report. (8863311)
1996
30
Sebaceous adenoma in the region of the medial canthus causing proptosis. (10707724)
1995
31
Sebaceous adenoma with a cutaneous horn. (7560356)
1995
32
Sebaceous adenoma of parotid gland--a rare tumour diagnosed by fine needle aspiration cytology. (7880973)
1994
33
CT of sebaceous adenoma of the parotid gland. (7976936)
1994
34
Sebaceous adenoma in a patient with acquired immunodeficiency syndrome. (3355190)
1988
35
Sebaceous adenoma of the oral mucosa. (3469349)
1987
36
Pathology quiz case 1: Sebaceous adenoma. (6849571)
1983
37
Sebaceous adenoma of the oral cavity. (6571741)
1983
38
Tissue connections in a transplantable virus-producing sebaceous adenoma of the mouse. II. A freeze-fracture study in conjunction with filipin. (6277960)
1982
39
Tissue connections in a transplantable virus-producing sebaceous adenoma of the mouse. (7338533)
1981
40
Sebaceous adenoma of the eyelid and visceral malignancy. (4440729)
1974
41
A SEBACEOUS ADENOMA. HISTOLOGICAL AND CHEMICAL STUDIES. (14183145)
1964
42
Sebaceous adenoma of the submaxillary salivary gland. Report of a case. (14011757)
1963
43
A REVIEW ON SEBACEOUS ADENOMA WITH REPORT OF A CASE IN THE EXTERNAL AUDITORY MEATUS. (14082064)
1963
44
Sebaceous adenoma in a dog. (13407925)
1957
45
Scalp: sebaceous adenoma. (13094140)
1953
46
Diethylstilbestrol in the treatment of senile sebaceous adenoma. (14952023)
1952
47
Sebaceous adenoma; review of the literature and report of a case. (18919779)
1948
48
Senile Sebaceous Adenoma. (19991727)
1938
49
Pringle Type of Sebaceous Adenoma. (19990196)
1935
50
Sebaceous Adenoma (Pringle Type) in Mother and Daughter. (19979593)
1917

Variations for Sebaceous Adenoma

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Expression for genes affiliated with Sebaceous Adenoma

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Search GEO for disease gene expression data for Sebaceous Adenoma.

Pathways for genes affiliated with Sebaceous Adenoma

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GO Terms for genes affiliated with Sebaceous Adenoma

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Cellular components related to Sebaceous Adenoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1MutSalpha complexGO:00323019.1MSH2, MSH6

Biological processes related to Sebaceous Adenoma according to GeneCards Suite gene sharing:

(show all 14)
idNameGO IDScoreTop Affiliating Genes
1somatic recombination of immunoglobulin genes involved in immune responseGO:00022049.9MLH1, MSH2
2mammary gland alveolus developmentGO:00607499.8EGF, ESR1
3meiotic mismatch repairGO:00007109.8MSH2, MSH6
4determination of adult lifespanGO:00083409.6MSH2, MSH6
5maintenance of DNA repeat elementsGO:00435709.6MSH2, MSH6
6negative regulation of DNA recombinationGO:00459109.6MSH2, MSH6
7positive regulation of helicase activityGO:00510969.5MSH2, MSH6
8somatic hypermutation of immunoglobulin genesGO:00164469.1MLH1, MSH2, MSH6
9somatic recombination of immunoglobulin gene segmentsGO:00164479.1MLH1, MSH2, MSH6
10mismatch repairGO:00062989.0MLH1, MSH2, MSH6
11isotype switchingGO:00451908.9MLH1, MSH2, MSH6
12intrinsic apoptotic signaling pathway in response to DNA damageGO:00086308.8MLH1, MSH2, MSH6
13DNA repairGO:00062818.5MLH1, MSH2, MSH6
14reciprocal meiotic recombinationGO:00071318.2MLH1, MSH2, MSH6

Molecular functions related to Sebaceous Adenoma according to GeneCards Suite gene sharing:

(show all 13)
idNameGO IDScoreTop Affiliating Genes
1single thymine insertion bindingGO:00321439.8MSH2, MSH6
2single guanine insertion bindingGO:00321429.8MSH2, MSH6
3oxidized purine DNA bindingGO:00323579.8MSH2, MSH6
4mismatched DNA bindingGO:00309839.7MSH2, MSH6
5MutLalpha complex bindingGO:00324059.7MSH2, MSH6
6ADP bindingGO:00435319.6MSH2, MSH6
7damaged DNA bindingGO:00036849.5MSH2, MSH6
8single-stranded DNA bindingGO:00036979.5MLH1, MSH2
9double-stranded DNA bindingGO:00036909.4MSH2, MSH6
10four-way junction DNA bindingGO:00004009.3MSH2, MSH6
11guanine/thymine mispair bindingGO:00321379.2MLH1, MSH2, MSH6
12chromatin bindingGO:00036828.6ESR1, MLH1, MSH6
13ATPase activityGO:00168878.6MLH1, MSH2, MSH6

Sources for Sebaceous Adenoma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet