MCID: SBC009
MIFTS: 32

Sebaceous Adenoma malady

Skin, Endocrine categories

Summaries for Sebaceous Adenoma

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64Wikipedia, 33MalaCards
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Wikipedia:64 Sebaceous adenoma is a cutaneous condition characterized by a slow-growing tumour usually presenting as... more...

MalaCards: Sebaceous Adenoma, also known as skin appendage sebaceous adenoma, is related to adenoma and colorectal cancer. An important gene associated with Sebaceous Adenoma is MSH2 (mutS homolog 2), and among its related pathways is Regulation of Telomerase. The compounds estradiol and anastrozole have been mentioned in the context of this disorder. Affiliated tissues include salivary gland and skin.

Aliases & Classifications for Sebaceous Adenoma

Sources:
8Disease Ontology, 10DISEASES, 61UMLS, 57SNOMED-CT, 40NCIt
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Skin, Endocrine


Aliases & Descriptions:

sebaceous adenoma 8 10 61
skin appendage sebaceous adenoma 8
adenoma of the sebaceous gland 8


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Disease Ontology8 DOID:2648
SNOMED-CT57 78424008
NCIt40 C4174

Related Diseases for Sebaceous Adenoma

Sources:
17GeneCards, 18GeneDecks
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Diseases related to Sebaceous Adenoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 52)
idRelated DiseaseScoreTop Affiliating Genes
1adenoma31.3MSH2, MKI67
2colorectal cancer30.1EGF, MSH2, MKI67
3muir-torre syndrome10.5
4ovarian cystic teratoma10.1
5acquired immunodeficiency syndrome10.1
6follicular infundibulum tumor10.1
7syringocystadenoma papilliferum10.1
8adenosquamous carcinoma10.1
9mucoepidermoid carcinoma10.1
10teratoma10.1
11leukoplakia10.0MKI67
12li-fraumeni syndrome10.0ESR1
13ductal carcinoma in situ10.0ESR1
14oligodendroglioma10.0MKI67
15adenosarcoma10.0ESR1
16gastrointestinal stromal tumor10.0MKI67
17laryngeal carcinoma10.0MKI67
18laryngeal squamous cell carcinoma10.0MKI67
19pituitary tumors10.0ESR1
20uterine sarcoma10.0ESR1
21cervical cancer10.0MSH2
22pituitary adenoma10.0MKI67
23endometriosis10.0ESR1
24cervical adenocarcinoma10.0ESR1
25uterine fibroid10.0ESR1
26prolactinoma10.0ESR1
27thyroid cancer10.0EGF
28cerebral meningioma10.0EGF
29hepatocellular carcinoma10.0MKI67
30breast cancer, invasive ductal10.0MKI67, ESR1
31breast fibroadenoma10.0MKI67, ESR1
32smooth muscle tumor10.0ESR1, MKI67
33malignant fibroxanthoma10.0MKI67, MSH2
34papillary carcinoma10.0MKI67, ESR1
35sarcoma10.0MSH2, MKI67
36keratoacanthoma10.0MKI67, MSH2
37squamous cell carcinoma10.0MKI67, EGF
38transitional cell carcinoma10.0MSH2, MKI67
39pheochromocytoma10.0MSH2, EGF
40colon cancer10.0MSH2, EGF
41pancreatic cancer10.0MSH2, EGF
42cervical squamous cell carcinoma10.0EGF, MKI67
43melanoma10.0MSH2, MKI67
44glioblastoma multiforme10.0EGF, MSH2
45meningioma10.0MKI67, ESR1, EGF
46leiomyoma10.0EGF, MKI67, ESR1
47stomach cancer10.0EGF, MSH2
48endometrial carcinoma10.0EGF, MSH2, ESR1
49astrocytoma10.0MSH2, MKI67, EGF
50ovarian cancer10.0MSH2, ESR1, EGF

Graphical network of the top 20 diseases related to Sebaceous Adenoma:



Diseases related to sebaceous adenoma

Clinical Features for Sebaceous Adenoma

Drugs & Therapeutics for Sebaceous Adenoma

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Sebaceous Adenoma

Anatomical Context for Sebaceous Adenoma

Sources:
33MalaCards
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MalaCards organs/tissues related to Sebaceous Adenoma:

33
Salivary gland, Skin

Animal Models for Sebaceous Adenoma or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Sebaceous Adenoma

Sources:
51PubMed
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Articles related to Sebaceous Adenoma:

(show top 50)    (show all 51)
idTitleAuthorsYear
1
A case of sebaceous adenoma of the eyelid showing excessively rapid growth. (23579539)
2013
2
Sebaceous adenoma arising within an ovarian mature cystic teratoma in Muir-Torre syndrome. (21684182)
2012
3
Fine needle aspiration biopsy of an unusual follicular adenoma with sebaceous-like features. (22527948)
2012
4
Metachronous occurrence of colorectal cancer in a muir-torre syndrome patient presenting with recurrent sebaceous adenoma of the eyelid: case report and updated review of the literature. (23149194)
2012
5
A rare case of sebaceous adenoma of the palate, with literature review. (21443818)
2011
6
Treatment of sebaceous adenoma with topical photodynamic therapy. (20956668)
2010
7
Sebaceous adenoma of the submandibular gland: a case report. (20032620)
2009
8
Mucoepidermoid (adenosquamous) carcinoma, trichoblastoma, trichilemmoma, sebaceous adenoma, tumor of follicular infundibulum and syringocystadenoma papilliferum arising within 2 persistent lesions of nevus sebaceous: report of a case. (19652586)
2009
9
Demodex-associated dermatologic conditions--A coincidence or an etiological correlate. Review with a report of a rare case of sebaceous adenoma. (19167837)
2009
10
Comparative clinicopathological study of intraoral sebaceous hyperplasia and sebaceous adenoma. (19101492)
2009
11
Sebaceous adenoma of the parotid gland: a case report with fine needle aspiration findings and histologic correlation. (19697727)
2009
12
Sebaceous adenoma of the parotid gland in a 2-year-old male. (17418275)
2007
13
Sebaceous adenoma of the bulbar conjunctiva in association with glioblastoma multiforme and chronic lymphocytic leukemia. (17893552)
2007
14
Penile sebaceous adenoma. (17637371)
2007
15
Sebaceous adenoma of the parotid gland. (16878064)
2006
16
Familial adenomatous polyposis (FAP): genotype correlation to FAP phenotype with osteomas and sebaceous cysts. (16411234)
2006
17
Carcinoma ex pleomorphic adenoma with sebaceous differentiation in the mandibular salivary gland of a dog. (16672588)
2006
18
Sebaceous adenoma of the eyelid in Muir-Torre syndrome. (15824235)
2005
19
Sebaceous gland adenoma of the tarsal conjunctiva in a patient with Muir-Torre syndrome. (13129885)
2003
20
Sebaceous adenoma in the retromolar region: report of a case with a review of the English literature. (14505629)
2003
21
Sebaceous adenoma of oral cavity: report of case and comparative proliferation study with sebaceous gland hyperplasia and Fordyce's granules. (14629335)
2003
22
Sebaceous adenoma of the cheek. (11755830)
2002
23
Loss of p21(WAF1) compartmentalisation in sebaceous carcinoma compared with sebaceous hyperplasia and sebaceous adenoma. (12354803)
2002
24
Sebaceous adenoma in the submandibular gland. (11870356)
2002
25
Sebaceous adenomas with atypical immunohistochemical features in the Muir-Torre syndrome [leter]. (10233335)
1999
26
Solitary facial lesion. Sebaceous adenoma in association with Muir-Torre syndrome (MTS). (9006382)
1997
27
Immunohistochemical study on sebaceous adenoma and sebaceous carcinoma arising in parotid gland. (21594425)
1996
28
Sebaceous adenoma in the region of the medial canthus causing proptosis. (10707724)
1995
29
Sebaceous adenoma with a cutaneous horn. (7560356)
1995
30
Sebaceous adenoma of parotid gland--a rare tumour diagnosed by fine needle aspiration cytology. (7880973)
1994
31
CT of sebaceous adenoma of the parotid gland. (7976936)
1994
32
Sebaceous gland adenoma of the palpebral conjunctiva in a patient with Muir-Torre-syndrome: a case report. (7890187)
1994
33
Sebaceous adenoma in a patient with acquired immunodeficiency syndrome. (3355190)
1988
34
Sebaceous adenoma of the oral mucosa. (3469349)
1987
35
Sebaceous adenoma of the oral cavity. (6571741)
1983
36
Pathology quiz case 1: Sebaceous adenoma. (6849571)
1983
37
Tissue connections in a transplantable virus-producing sebaceous adenoma of the mouse. II. A freeze-fracture study in conjunction with filipin. (6277960)
1982
38
Tissue connections in a transplantable virus-producing sebaceous adenoma of the mouse. (7338533)
1981
39
The sebaceous duct adenoma (so-called syringoma). (1086963)
1976
40
Sebaceous adenoma of the eyelid and visceral malignancy. (4440729)
1974
41
A SEBACEOUS ADENOMA. HISTOLOGICAL AND CHEMICAL STUDIES. (14183145)
1964
42
Sebaceous adenoma of the submaxillary salivary gland. Report of a case. (14011757)
1963
43
A REVIEW ON SEBACEOUS ADENOMA WITH REPORT OF A CASE IN THE EXTERNAL AUDITORY MEATUS. (14082064)
1963
44
Sebaceous adenoma in a dog. (13407925)
1957
45
Scalp: sebaceous adenoma. (13094140)
1953
46
Diethylstilbestrol in the treatment of senile sebaceous adenoma. (14952023)
1952
47
Sebaceous adenoma; review of the literature and report of a case. (18919779)
1948
48
Senile Sebaceous Adenoma. (19991727)
1938
49
Pringle Type of Sebaceous Adenoma. (19990196)
1935
50
Sebaceous Adenoma (Pringle Type) in Mother and Daughter. (19979593)
1917

Genetic Variations for Sebaceous Adenoma

Expression for genes affiliated with Sebaceous Adenoma

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Sebaceous Adenoma

Search GEO for disease gene expression data for Sebaceous Adenoma.

Pathways for genes affiliated with Sebaceous Adenoma

Sources:
38NCBI BioSystems Database
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Pathways related to Sebaceous Adenoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.3ESR1, EGF

Compounds for genes affiliated with Sebaceous Adenoma

Sources:
45Novoseek, 11DrugBank, 24HMDB, 29IUPHAR, 50PharmGKB, 60Tocris Bioscience
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Compounds related to Sebaceous Adenoma according to GeneCards/GeneDecks:

(show all 29)
idCompoundScoreTop Affiliating Genes
1estradiol45 11 2412.3MKI67
2anastrozole45 1110.7MKI67, ESR1
3hydroxyflutamide45 2910.7EGF, ESR1
4lapatinib45 50 1111.7ESR1, EGF
5octreotide45 60 29 1112.7MKI67, EGF
6letrozole45 50 60 1112.7ESR1, MKI67
7paclitaxel45 50 1111.7ESR1, EGF
8bicalutamide45 60 1111.7ESR1, EGF
917beta-hydroxysteroid459.6ESR1, MKI67
10progestins459.6ESR1, MKI67
11trastuzumab45 50 1111.6EGF, ESR1
12irinotecan45 50 1111.6MKI67, EGF
134-hydroxytamoxifen459.5ESR1, EGF
14biotin45 11 2411.5MSH2, MKI67
15gefitinib45 50 1111.4ESR1, EGF
16progestin459.3EGF, ESR1
17cisplatin45 50 60 1112.3MSH2, MKI67, EGF
18fulvestrant45 50 29 1112.2ESR1, MKI67, EGF
19mifepristone45 60 29 1112.2ESR1, MKI67, EGF
20paraffin459.2MKI67, MSH2, ESR1
21gnrh459.2ESR1, MKI67, EGF
22tamoxifen45 50 29 1112.2EGF, MKI67, ESR1
23geldanamycin45 50 60 1112.0ESR1, EGF
24cycloheximide459.0ESR1, MKI67, EGF
25progesterone45 60 29 11 2413.0EGF, MKI67, ESR1
26testosterone45 60 11 2411.9ESR1, MKI67, EGF
275fluorouracil458.7ESR1, MSH2, MKI67, EGF
28doxorubicin45 50 1110.7EGF, MKI67, MSH2, ESR1
29steroid458.7ESR1, MKI67, EGF

GO Terms for genes affiliated with Sebaceous Adenoma

Sources:
16Gene Ontology
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Biological processes related to Sebaceous Adenoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1male gonad developmentGO:0085849.4ESR1, MSH2
2mammary gland alveolus developmentGO:0607499.0ESR1, EGF

Products for genes affiliated with Sebaceous Adenoma

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Sources for Sebaceous Adenoma

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet