MCID: SBC009
MIFTS: 36

Sebaceous Adenoma malady

Skin diseases, Endocrine diseases categories

Summaries for Sebaceous Adenoma

About this section
Sources:
63Wikipedia, 32MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
Wikipedia:63 Sebaceous adenoma is a cutaneous condition characterized by a slow-growing tumour usually presenting as... more...

MalaCards: Sebaceous Adenoma, also known as skin appendage sebaceous adenoma, is related to adenoma and glioblastoma multiforme. An important gene associated with Sebaceous Adenoma is MSH2 (mutS homolog 2), and among its related pathways is Regulation of Telomerase. The compounds estradiol and anastrozole have been mentioned in the context of this disorder. Affiliated tissues include skin and salivary gland.

Aliases & Classifications for Sebaceous Adenoma

About this section
Sources:
8Disease Ontology, 10DISEASES, 60UMLS, 56SNOMED-CT, 39NCIt
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Skin diseases, Endocrine diseases


Aliases & Descriptions:

sebaceous adenoma 8 10 60
skin appendage sebaceous adenoma 8
adenoma of the sebaceous gland 8


External Ids:

Disease Ontology8 DOID:2648
SNOMED-CT56 78424008
NCIt39 C4174

Related Diseases for Sebaceous Adenoma

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Sebaceous Adenoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 57)
idRelated DiseaseScoreTop Affiliating Genes
1adenoma31.3MSH2, MKI67
2glioblastoma multiforme30.0MSH2, EGF
3colorectal cancer30.0MSH2, MKI67, EGF
4muir-torre syndrome10.4
5ovarian cystic teratoma10.0
6acquired immunodeficiency syndrome10.0
7follicular infundibulum tumor10.0
8syringocystadenoma papilliferum10.0
9adenosquamous carcinoma10.0
10mucoepidermoid carcinoma10.0
11chronic lymphocytic leukemia10.0
12conjunctivitis10.0
13cystic teratoma10.0
14follicular adenoma10.0
15leukemia10.0
16mature teratoma10.0
17leukoplakia10.0MKI67
18li-fraumeni syndrome10.0ESR1
19ductal carcinoma in situ10.0ESR1
20oligodendroglioma10.0MKI67
21adenosarcoma10.0ESR1
22gastrointestinal stromal tumor10.0MKI67
23laryngeal benign neoplasm10.0MKI67
24laryngeal squamous cell carcinoma10.0MKI67
25pituitary tumors10.0ESR1
26uterine sarcoma10.0ESR1
27cervical cancer10.0MSH2
28pituitary adenoma10.0MKI67
29endometriosis10.0ESR1
30cervical adenocarcinoma10.0ESR1
31uterine fibroid10.0ESR1
32prolactinoma10.0ESR1
33thyroid cancer10.0EGF
34cerebral meningioma10.0EGF
35hepatocellular carcinoma10.0MKI67
36breast cancer, invasive ductal10.0MKI67, ESR1
37breast fibroadenoma10.0ESR1, MKI67
38smooth muscle tumor10.0ESR1, MKI67
39malignant fibroxanthoma10.0MKI67, MSH2
40papillary carcinoma10.0ESR1, MKI67
41sarcoma10.0MSH2, MKI67
42keratoacanthoma10.0MSH2, MKI67
43squamous cell carcinoma10.0MKI67, EGF
44transitional cell carcinoma10.0MSH2, MKI67
45pheochromocytoma10.0MSH2, EGF
46colon cancer10.0EGF, MSH2
47pancreatic cancer10.0MSH2, EGF
48cervical squamous cell carcinoma10.0MKI67, EGF
49melanoma10.0MSH2, MKI67
50meningioma10.0ESR1, MKI67, EGF

Graphical network of the top 20 diseases related to Sebaceous Adenoma:



Diseases related to sebaceous adenoma

Clinical Features for Sebaceous Adenoma

About this section

Drugs & Therapeutics for Sebaceous Adenoma

About this section
Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Sebaceous Adenoma

Drug clinical trials:

Search ClinicalTrials for Sebaceous Adenoma

Search NIH Clinical Center for Sebaceous Adenoma

Search CenterWatch for Sebaceous Adenoma

Genetic Tests for Sebaceous Adenoma

About this section

Anatomical Context for Sebaceous Adenoma

About this section
Sources:
32MalaCards
See all sources

MalaCards organs/tissues related to Sebaceous Adenoma:

32
Skin, Salivary gland

Animal Models for Sebaceous Adenoma or affiliated genes

About this section

Publications for Sebaceous Adenoma

About this section
Sources:
50PubMed
See all sources

Articles related to Sebaceous Adenoma:

(show all 50)
idTitleAuthorsYear
1
A case of sebaceous adenoma of the eyelid showing excessively rapid growth. (23579539)
2013
2
Sebaceous adenoma arising within an ovarian mature cystic teratoma in Muir-Torre syndrome. (21684182)
2012
3
Fine needle aspiration biopsy of an unusual follicular adenoma with sebaceous-like features. (22527948)
2012
4
Metachronous occurrence of colorectal cancer in a muir-torre syndrome patient presenting with recurrent sebaceous adenoma of the eyelid: case report and updated review of the literature. (23149194)
2012
5
A rare case of sebaceous adenoma of the palate, with literature review. (21443818)
2011
6
Treatment of sebaceous adenoma with topical photodynamic therapy. (20956668)
2010
7
Sebaceous adenoma of the submandibular gland: a case report. (20032620)
2009
8
Mucoepidermoid (adenosquamous) carcinoma, trichoblastoma, trichilemmoma, sebaceous adenoma, tumor of follicular infundibulum and syringocystadenoma papilliferum arising within 2 persistent lesions of nevus sebaceous: report of a case. (19652586)
2009
9
Demodex-associated dermatologic conditions--A coincidence or an etiological correlate. Review with a report of a rare case of sebaceous adenoma. (19167837)
2009
10
Comparative clinicopathological study of intraoral sebaceous hyperplasia and sebaceous adenoma. (19101492)
2009
11
Sebaceous adenoma of the parotid gland: a case report with fine needle aspiration findings and histologic correlation. (19697727)
2009
12
Sebaceous adenoma of the parotid gland in a 2-year-old male. (17418275)
2007
13
Sebaceous adenoma of the bulbar conjunctiva in association with glioblastoma multiforme and chronic lymphocytic leukemia. (17893552)
2007
14
Penile sebaceous adenoma. (17637371)
2007
15
Sebaceous adenoma of the parotid gland. (16878064)
2006
16
Carcinoma ex pleomorphic adenoma with sebaceous differentiation in the mandibular salivary gland of a dog. (16672588)
2006
17
Sebaceous adenoma of the eyelid in Muir-Torre syndrome. (15824235)
2005
18
Sebaceous gland adenoma of the tarsal conjunctiva in a patient with Muir-Torre syndrome. (13129885)
2003
19
Sebaceous adenoma in the retromolar region: report of a case with a review of the English literature. (14505629)
2003
20
Sebaceous adenoma of oral cavity: report of case and comparative proliferation study with sebaceous gland hyperplasia and Fordyce's granules. (14629335)
2003
21
Sebaceous adenoma of the cheek. (11755830)
2002
22
Loss of p21(WAF1) compartmentalisation in sebaceous carcinoma compared with sebaceous hyperplasia and sebaceous adenoma. (12354803)
2002
23
Sebaceous adenoma in the submandibular gland. (11870356)
2002
24
Sebaceous adenomas with atypical immunohistochemical features in the Muir-Torre syndrome [leter]. (10233335)
1999
25
Solitary facial lesion. Sebaceous adenoma in association with Muir-Torre syndrome (MTS). (9006382)
1997
26
Immunohistochemical study on sebaceous adenoma and sebaceous carcinoma arising in parotid gland. (21594425)
1996
27
Sebaceous adenoma of the submandibular gland: a case report. (8863311)
1996
28
Sebaceous adenoma in the region of the medial canthus causing proptosis. (10707724)
1995
29
Sebaceous adenoma with a cutaneous horn. (7560356)
1995
30
Sebaceous adenoma of parotid gland--a rare tumour diagnosed by fine needle aspiration cytology. (7880973)
1994
31
CT of sebaceous adenoma of the parotid gland. (7976936)
1994
32
Sebaceous gland adenoma of the palpebral conjunctiva in a patient with Muir-Torre-syndrome: a case report. (7890187)
1994
33
Sebaceous adenoma in a patient with acquired immunodeficiency syndrome. (3355190)
1988
34
Sebaceous adenoma of the oral mucosa. (3469349)
1987
35
Sebaceous adenoma of the oral cavity. (6571741)
1983
36
Pathology quiz case 1: Sebaceous adenoma. (6849571)
1983
37
Tissue connections in a transplantable virus-producing sebaceous adenoma of the mouse. II. A freeze-fracture study in conjunction with filipin. (6277960)
1982
38
Tissue connections in a transplantable virus-producing sebaceous adenoma of the mouse. (7338533)
1981
39
The sebaceous duct adenoma (so-called syringoma). (1086963)
1976
40
Sebaceous adenoma of the eyelid and visceral malignancy. (4440729)
1974
41
A SEBACEOUS ADENOMA. HISTOLOGICAL AND CHEMICAL STUDIES. (14183145)
1964
42
Sebaceous adenoma of the submaxillary salivary gland. Report of a case. (14011757)
1963
43
A REVIEW ON SEBACEOUS ADENOMA WITH REPORT OF A CASE IN THE EXTERNAL AUDITORY MEATUS. (14082064)
1963
44
Sebaceous adenoma in a dog. (13407925)
1957
45
Scalp: sebaceous adenoma. (13094140)
1953
46
Diethylstilbestrol in the treatment of senile sebaceous adenoma. (14952023)
1952
47
Sebaceous adenoma; review of the literature and report of a case. (18919779)
1948
48
Senile Sebaceous Adenoma. (19991727)
1938
49
Pringle Type of Sebaceous Adenoma. (19990196)
1935
50
Sebaceous Adenoma (Pringle Type) in Mother and Daughter. (19979593)
1917

Genetic Variations for Sebaceous Adenoma

About this section

Expression for genes affiliated with Sebaceous Adenoma

About this section
Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Sebaceous Adenoma

Search GEO for disease gene expression data for Sebaceous Adenoma.

Pathways for genes affiliated with Sebaceous Adenoma

About this section
Sources:
37NCBI BioSystems Database
See all sources

Pathways related to Sebaceous Adenoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.3ESR1, EGF

Compounds for genes affiliated with Sebaceous Adenoma

About this section
Sources:
44Novoseek, 11DrugBank, 24HMDB, 28IUPHAR, 49PharmGKB, 59Tocris Bioscience
See all sources

Compounds related to Sebaceous Adenoma according to GeneCards/GeneDecks:

(show all 29)
idCompoundScoreTop Affiliating Genes
1estradiol44 11 2412.3MKI67
2anastrozole44 1110.7MKI67, ESR1
3hydroxyflutamide44 2810.7EGF, ESR1
4lapatinib44 49 1111.7ESR1, EGF
5octreotide44 59 28 1112.7MKI67, EGF
6letrozole44 49 59 1112.7ESR1, MKI67
7paclitaxel44 49 1111.7ESR1, EGF
8bicalutamide44 59 1111.7ESR1, EGF
917beta-hydroxysteroid449.6ESR1, MKI67
10progestins449.6ESR1, MKI67
11trastuzumab44 49 1111.6EGF, ESR1
12irinotecan44 49 1111.6MKI67, EGF
134-hydroxytamoxifen449.5ESR1, EGF
14biotin44 11 2411.5MSH2, MKI67
15gefitinib44 49 1111.4ESR1, EGF
16progestin449.3EGF, ESR1
17cisplatin44 49 59 1112.3MSH2, MKI67, EGF
18fulvestrant44 49 28 1112.2ESR1, MKI67, EGF
19mifepristone44 59 28 1112.2ESR1, MKI67, EGF
20paraffin449.2MKI67, MSH2, ESR1
21gnrh449.2ESR1, MKI67, EGF
22tamoxifen44 49 28 1112.2EGF, MKI67, ESR1
23geldanamycin44 49 59 1112.0ESR1, EGF
24cycloheximide449.0ESR1, MKI67, EGF
25progesterone44 59 28 11 2413.0EGF, MKI67, ESR1
26testosterone44 59 11 2411.9ESR1, MKI67, EGF
275fluorouracil448.7ESR1, MSH2, MKI67, EGF
28doxorubicin44 49 1110.7EGF, MKI67, MSH2, ESR1
29steroid448.7ESR1, MKI67, EGF

GO Terms for genes affiliated with Sebaceous Adenoma

About this section
Sources:
16Gene Ontology
See all sources

Biological processes related to Sebaceous Adenoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1male gonad developmentGO:0085849.4ESR1, MSH2
2mammary gland alveolus developmentGO:0607499.0ESR1, EGF

Products for genes affiliated with Sebaceous Adenoma

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Sebaceous Adenoma

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet