MCID: SBC009
MIFTS: 33

Sebaceous Adenoma malady

Categories: Cancer diseases, Skin diseases, Endocrine diseases

Aliases & Classifications for Sebaceous Adenoma

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Aliases & Descriptions for Sebaceous Adenoma:

Name: Sebaceous Adenoma 11 13 68
Skin Appendage Sebaceous Adenoma 11
 
Adenoma of the Sebaceous Gland 11

Classifications:



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Disease Ontology11 DOID:2648
SNOMED-CT62 78424008
NCIt45 C4174

Summaries for Sebaceous Adenoma

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Wikipedia:71 A sebaceous adenoma, a type of adenoma, a cutaneous condition characterized by a slow-growing tumor... more...

MalaCards based summary: Sebaceous Adenoma, also known as skin appendage sebaceous adenoma, is related to adenoma and deafness, autosomal recessive 74. An important gene associated with Sebaceous Adenoma is EGF (Epidermal Growth Factor), and among its related pathways are Regulation of Telomerase and Busulfan Pathway, Pharmacodynamics. Affiliated tissues include skin and salivary gland, and related mouse phenotypes are digestive/alimentary and integument.

Related Diseases for Sebaceous Adenoma

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Diseases related to Sebaceous Adenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 58)
idRelated DiseaseScoreTop Affiliating Genes
1adenoma10.5
2deafness, autosomal recessive 7410.1EGF, ESR1
3esophagus sarcoma10.1EGF, ESR1
4her2-receptor positive breast cancer10.1EGF, ESR1
5haverhill fever10.1EGF, ESR1
6muir-torre syndrome10.1
7skin melanoma10.1MLH1, MSH2
8fibrolamellar carcinoma10.0MLH1, MSH2
9familial hypopituitarism10.0MLH1, MSH2
10neurocutaneous melanosis, somatic10.0MLH1, MSH2
11collecting duct carcinoma10.0MLH1, MSH2
12malignant spindle cell melanoma10.0MLH1, MSH2
13plague10.0EGF, ESR1
14ideomotor apraxia10.0MLH1, MSH2
15autoimmune autonomic ganglionopathy10.0MSH2, MSH6
16prostatic adenoma10.0ESR1, MLH1
17larynx liposarcoma10.0MLH1, MSH2
18cardiomyopathy, dilated, 1r10.0MSH2, MSH6
19trypanosomiasis9.9MLH1, MSH6
20aorta atresia9.9EGF, MLH1, MSH2
21nevoid hypermelanosis, linear and whorled9.9EGF, ESR1, MLH1
22congenital symblepharon9.9MLH1, MSH2
23rectum sarcoma9.9MLH1, MSH2
24rhinosporidiosis9.9EGF, ESR1, MLH1
25oral squamous cell carcinoma9.8MLH1, MSH2
26large intestine adenoma9.8MLH1, MSH2, MSH6
27neuropathy, distal hereditary motor, type viib9.8MLH1, MSH2, MSH6
28churg-strauss syndrome9.8MLH1, MSH2, MSH6
29cauda equina neoplasm9.8MLH1, MSH2, MSH6
30neurofibromatosis-noonan syndrome9.8MLH1, MSH2, MSH6
31mismatch repair cancer syndrome9.8MLH1, MSH2, MSH6
32neuroretinitis9.8MLH1, MSH2, MSH6
33fibromatosis, gingival, 19.8MLH1, MSH2, MSH6
34hnrnpa1-related amyotrophic lateral sclerosis9.7MLH1, MSH2, MSH6
35wolffian duct adenoma9.7MLH1, MSH2, MSH6
36skin papilloma9.7MLH1, MSH2, MSH6
37asperger syndrome9.7MLH1, MSH2, MSH6
38autosomal genetic disease9.7MLH1, MSH2, MSH6
39t-cell large granular lymphocyte leukemia9.7MLH1, MSH2, MSH6
40seborrheic dermatitis9.7MLH1, MSH2, MSH6
41hidradenoma9.7MLH1, MSH2, MSH6
42proctitis9.7MLH1, MSH2, MSH6
43colorectal cancer9.7
44chronic lymphocytic leukemia9.7
45leukemia9.7
46cystic teratoma9.7
47glioblastoma multiforme9.7
48teratoma9.7
49adenosquamous carcinoma9.7
50syringocystadenoma papilliferum9.7

Graphical network of the top 20 diseases related to Sebaceous Adenoma:



Diseases related to sebaceous adenoma

Symptoms & Phenotypes for Sebaceous Adenoma

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MGI Mouse Phenotypes related to Sebaceous Adenoma according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053818.7CYLD, EGF, ESR1, MLH1, MSH2
2MP:00107717.8CYLD, EGF, ESR1, MLH1, MSH2, MSH6
3MP:00020067.5CYLD, ESR1, MLH1, MSH2, MSH6

Drugs & Therapeutics for Sebaceous Adenoma

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Sebaceous Adenoma

Genetic Tests for Sebaceous Adenoma

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Anatomical Context for Sebaceous Adenoma

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MalaCards organs/tissues related to Sebaceous Adenoma:

36
Skin, Salivary gland

Publications for Sebaceous Adenoma

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Articles related to Sebaceous Adenoma:

(show top 50)    (show all 51)
idTitleAuthorsYear
1
Sebaceous adenomas in the absence of Muir-Torre syndrome. (27769341)
2016
2
A unique case of isolated sebaceous adenoma of the bulbar conjunctiva. (27626151)
2016
3
Sebaceous adenomas of the eyelid and Muir-Torre Syndrome. (25595178)
2015
4
Sebaceous Adenoma of the Caruncle. (26398052)
2015
5
Sebaceous adenoma: clinics, dermatoscopy, and histopathology. (25311786)
2014
6
Corneal limbal sebaceous adenoma. (24556852)
2014
7
A case of sebaceous adenoma of the eyelid showing excessively rapid growth. (23579539)
2013
8
Metachronous occurrence of colorectal cancer in a muir-torre syndrome patient presenting with recurrent sebaceous adenoma of the eyelid: case report and updated review of the literature. (23149194)
2012
9
Sebaceous adenoma arising within an ovarian mature cystic teratoma in Muir-Torre syndrome. (21684182)
2012
10
A rare case of sebaceous adenoma of the palate, with literature review. (21443818)
2011
11
Treatment of sebaceous adenoma with topical photodynamic therapy. (20956668)
2010
12
Sebaceous adenoma of the submandibular gland: a case report. (20032620)
2009
13
Demodex-associated dermatologic conditions--A coincidence or an etiological correlate. Review with a report of a rare case of sebaceous adenoma. (19167837)
2009
14
Comparative clinicopathological study of intraoral sebaceous hyperplasia and sebaceous adenoma. (19101492)
2009
15
Sebaceous adenoma of the parotid gland: a case report with fine needle aspiration findings and histologic correlation. (19697727)
2009
16
Mucoepidermoid (adenosquamous) carcinoma, trichoblastoma, trichilemmoma, sebaceous adenoma, tumor of follicular infundibulum and syringocystadenoma papilliferum arising within 2 persistent lesions of nevus sebaceous: report of a case. (19652586)
2009
17
Sebaceous adenoma of the parotid gland in a 2-year-old male. (17418275)
2007
18
Sebaceous adenoma of the bulbar conjunctiva in association with glioblastoma multiforme and chronic lymphocytic leukemia. (17893552)
2007
19
Penile sebaceous adenoma. (17637371)
2007
20
Sebaceous adenoma of the parotid gland. (16878064)
2006
21
Sebaceous adenoma of the eyelid in Muir-Torre syndrome. (15824235)
2005
22
Sebaceous adenoma in the retromolar region: report of a case with a review of the English literature. (14505629)
2003
23
Sebaceous adenoma of oral cavity: report of case and comparative proliferation study with sebaceous gland hyperplasia and Fordyce's granules. (14629335)
2003
24
Sebaceous adenoma in the submandibular gland. (11870356)
2002
25
Loss of p21(WAF1) compartmentalisation in sebaceous carcinoma compared with sebaceous hyperplasia and sebaceous adenoma. (12354803)
2002
26
Sebaceous adenoma of the cheek. (11755830)
2002
27
Sebaceous adenomas with atypical immunohistochemical features in the Muir-Torre syndrome [leter]. (10233335)
1999
28
Solitary facial lesion. Sebaceous adenoma in association with Muir-Torre syndrome (MTS). (9006382)
1997
29
Immunohistochemical study on sebaceous adenoma and sebaceous carcinoma arising in parotid gland. (21594425)
1996
30
Sebaceous adenoma of the submandibular gland: a case report. (8863311)
1996
31
Sebaceous adenoma with a cutaneous horn. (7560356)
1995
32
Sebaceous adenoma in the region of the medial canthus causing proptosis. (10707724)
1995
33
Sebaceous adenoma of parotid gland--a rare tumour diagnosed by fine needle aspiration cytology. (7880973)
1994
34
CT of sebaceous adenoma of the parotid gland. (7976936)
1994
35
Sebaceous adenoma in a patient with acquired immunodeficiency syndrome. (3355190)
1988
36
Sebaceous adenoma of the oral mucosa. (3469349)
1987
37
Pathology quiz case 1: Sebaceous adenoma. (6849571)
1983
38
Sebaceous adenoma of the oral cavity. (6571741)
1983
39
Tissue connections in a transplantable virus-producing sebaceous adenoma of the mouse. II. A freeze-fracture study in conjunction with filipin. (6277960)
1982
40
Tissue connections in a transplantable virus-producing sebaceous adenoma of the mouse. (7338533)
1981
41
Sebaceous adenoma of the eyelid and visceral malignancy. (4440729)
1974
42
A SEBACEOUS ADENOMA. HISTOLOGICAL AND CHEMICAL STUDIES. (14183145)
1964
43
A REVIEW ON SEBACEOUS ADENOMA WITH REPORT OF A CASE IN THE EXTERNAL AUDITORY MEATUS. (14082064)
1963
44
Sebaceous adenoma of the submaxillary salivary gland. Report of a case. (14011757)
1963
45
Sebaceous adenoma in a dog. (13407925)
1957
46
Scalp: sebaceous adenoma. (13094140)
1953
47
Diethylstilbestrol in the treatment of senile sebaceous adenoma. (14952023)
1952
48
Sebaceous adenoma; review of the literature and report of a case. (18919779)
1948
49
Senile Sebaceous Adenoma. (19991727)
1938
50
Pringle Type of Sebaceous Adenoma. (19990196)
1935

Variations for Sebaceous Adenoma

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Expression for genes affiliated with Sebaceous Adenoma

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Search GEO for disease gene expression data for Sebaceous Adenoma.

Pathways for genes affiliated with Sebaceous Adenoma

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Pathways related to Sebaceous Adenoma according to GeneCards Suite gene sharing:

(show all 14)
idSuper pathwaysScoreTop Affiliating Genes
19.6EGF, ESR1
2
Show member pathways
9.3MLH1, MSH2
3
Show member pathways
9.3MLH1, MSH2
49.1MSH2, MSH6
5
Show member pathways
9.1MSH2, MSH6
6
Show member pathways
8.7ESR1, MSH2, MSH6
78.7ESR1, MSH2, MSH6
88.5MLH1, MSH2, MSH6
98.5MLH1, MSH2, MSH6
10
Show member pathways
8.5MLH1, MSH2, MSH6
118.5MLH1, MSH2, MSH6
12
Show member pathways
8.1EGF, MLH1, MSH2, MSH6
138.1EGF, MLH1, MSH2, MSH6
148.1EGF, MLH1, MSH2, MSH6

GO Terms for genes affiliated with Sebaceous Adenoma

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Cellular components related to Sebaceous Adenoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1MutSalpha complexGO:00323019.1MSH2, MSH6

Biological processes related to Sebaceous Adenoma according to GeneCards Suite gene sharing:

(show all 15)
idNameGO IDScoreTop Affiliating Genes
1mammary gland alveolus developmentGO:006074910.1EGF, ESR1
2determination of adult lifespanGO:00083409.8MSH2, MSH6
3positive regulation of isotype switching to IgA isotypesGO:00482989.7MLH1, MSH2
4positive regulation of isotype switching to IgG isotypesGO:00483049.7MLH1, MSH2
5maintenance of DNA repeat elementsGO:00435709.7MSH2, MSH6
6negative regulation of DNA recombinationGO:00459109.6MSH2, MSH6
7positive regulation of helicase activityGO:00510969.6MSH2, MSH6
8somatic recombination of immunoglobulin genes involved in immune responseGO:00022049.3MLH1, MSH2
9cellular response to DNA damage stimulusGO:00069749.2MLH1, MSH2, MSH6
10DNA repairGO:00062819.1MLH1, MSH2, MSH6
11intrinsic apoptotic signaling pathway in response to DNA damageGO:00086309.1MLH1, MSH2, MSH6
12isotype switchingGO:00451909.0MLH1, MSH2, MSH6
13mismatch repairGO:00062989.0MLH1, MSH2, MSH6
14somatic hypermutation of immunoglobulin genesGO:00164468.7MLH1, MSH2, MSH6
15somatic recombination of immunoglobulin gene segmentsGO:00164478.4MLH1, MSH2, MSH6

Molecular functions related to Sebaceous Adenoma according to GeneCards Suite gene sharing:

(show all 13)
idNameGO IDScoreTop Affiliating Genes
1ADP bindingGO:00435319.8MSH2, MSH6
2damaged DNA bindingGO:00036849.8MSH2, MSH6
3four-way junction DNA bindingGO:00004009.8MSH2, MSH6
4MutLalpha complex bindingGO:00324059.8MSH2, MSH6
5oxidized purine DNA bindingGO:00323579.8MSH2, MSH6
6single guanine insertion bindingGO:00321429.7MSH2, MSH6
7single thymine insertion bindingGO:00321439.7MSH2, MSH6
8protein kinase bindingGO:00199019.5CYLD, ESR1, MSH2
9single-stranded DNA bindingGO:00036979.3MLH1, MSH2
10chromatin bindingGO:00036829.2ESR1, MLH1, MSH6
11ATPase activityGO:00168879.2MLH1, MSH2, MSH6
12guanine/thymine mispair bindingGO:00321379.2MLH1, MSH2, MSH6
13mismatched DNA bindingGO:00309839.2MLH1, MSH2, MSH6

Sources for Sebaceous Adenoma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet