MCID: SMN006
MIFTS: 30

Seminal Vesicle Tumor malady

Cancer diseases category

Summaries for Seminal Vesicle Tumor

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32MalaCards
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MalaCards: Seminal Vesicle Tumor, also known as tumor of seminal vesicle, is related to small cell carcinoma and adenosarcoma. An important gene associated with Seminal Vesicle Tumor is DIRC2 (disrupted in renal carcinoma 2), and among its related pathways are Carbon metabolism and Citric acid cycle (TCA cycle). The compounds UBIQUINONE-1 and thenoyltrifluoroacetone have been mentioned in the context of this disorder. Affiliated tissues include breast, uterus and t cells.

Aliases & Classifications for Seminal Vesicle Tumor

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8Disease Ontology, 10DISEASES, 60UMLS, 56SNOMED-CT, 39NCIt
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


Aliases & Descriptions:

seminal vesicle tumor 8 10
tumor of seminal vesicle 8 60
seminal vesicle neoplasm 8


External Ids:

Disease Ontology8 DOID:3855
SNOMED-CT56 236740006
NCIt39 C39908

Related Diseases for Seminal Vesicle Tumor

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17GeneCards, 18GeneDecks
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Diseases related to Seminal Vesicle Tumor via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 12)
idRelated DiseaseScoreTop Affiliating Genes
1small cell carcinoma10.2
2adenosarcoma10.2
3renal cell carcinoma10.2
4carney triad10.0SDHB
5hereditary paraganglioma-pheochromocytoma syndromes10.0SDHB
6chondroma10.0SDHB
7von hippel-lindau disease10.0SDHB
8leigh disease10.0SDHA, SDHB
9paraganglioma10.0SDHB, SDHA
10pheochromocytoma10.0SDHA, SDHB
11hyperthyroidism10.0SDHA, SDHB
12gastrointestinal stromal tumor10.0SDHA, SDHB

Graphical network of diseases related to Seminal Vesicle Tumor:



Diseases related to seminal vesicle tumor

Clinical Features for Seminal Vesicle Tumor

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Drugs & Therapeutics for Seminal Vesicle Tumor

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Seminal Vesicle Tumor

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Anatomical Context for Seminal Vesicle Tumor

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32MalaCards
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MalaCards organs/tissues related to Seminal Vesicle Tumor:

32
Breast, Uterus, T cells, Prostate

Animal Models for Seminal Vesicle Tumor or affiliated genes

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Publications for Seminal Vesicle Tumor

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50PubMed
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Articles related to Seminal Vesicle Tumor:

(show all 11)
idTitleAuthorsYear
1
Radiology-pathology conference: malignant solitary fibrous tumor of the seminal vesicle. (23466005)
2013
2
Recurrent mullerian adenosarcoma like tumor of seminal vesicle. (20551553)
2010
3
Peripheral primitive neuroectodermal tumor arising from the seminal vesicle. (18362495)
2008
4
Epithelial-stromal tumor of seminal vesicle in a patient with chromophobe renal cell carcinoma and small lymphocytic lymphoma. (18995209)
2008
5
Primary myxoid solitary fibrous tumor involving the seminal vesicle. (16984624)
2006
6
Epithelial-stromal tumor of the seminal vesicles in the transgenic adenocarcinoma mouse prostate model. (15872376)
2005
7
Large solitary fibrous tumor of the seminal vesicle. (14624929)
2003
8
Potent inhibition of CD4/TCR-mediated T cell apoptosis by a CD4-binding glycoprotein secreted from breast tumor and seminal vesicle cells. (10072505)
1999
9
Biosynthesis and immunobiochemical characterization of gp17/GCDFP-15. A glycoprotein from seminal vesicles and from breast tumors, in HeLa cells and in Pichia pastoris yeast. (10504398)
1999
10
Benign peripheral nerve sheath tumor of the seminal vesicle. (9534215)
1998
11
Laparoscopic removal of uterus, seminal vesicle and bilateral ovotestes harboring mature teratoma and carcinoid tumor in an intersex patient. (8618321)
1996

Genetic Variations for Seminal Vesicle Tumor

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Expression for genes affiliated with Seminal Vesicle Tumor

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Seminal Vesicle Tumor

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Pathways for genes affiliated with Seminal Vesicle Tumor

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29KEGG, 53Reactome, 37NCBI BioSystems Database, 12EMD Millipore
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Pathways related to Seminal Vesicle Tumor according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.1SDHA, SDHB
2
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9.1SDHA, SDHB
3
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9.1SDHA, SDHB
4
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9.1SDHA, SDHB

Compounds for genes affiliated with Seminal Vesicle Tumor

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11DrugBank, 44Novoseek, 28IUPHAR, 24HMDB
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Compounds related to Seminal Vesicle Tumor according to GeneCards/GeneDecks:

(show all 11)
idCompoundScoreTop Affiliating Genes
1UBIQUINONE-1119.4SDHA, SDHB
2thenoyltrifluoroacetone44 1110.4SDHA, SDHB
32-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol119.3SDHB, SDHA
4iron-sulfur449.3SDHA, SDHB
5succinic acid28 11 2411.3SDHA, SDHB
6ubiquinone449.2SDHB, SDHA
7succinate449.2SDHA, SDHB
8nad+449.1SDHA, SDHB
9iron44 2410.1SDHA, SDHB
10glyceraldehyde 3-phosphate449.0SDHB, SDHA
11nadh44 11 2410.8SDHA, SDHB

GO Terms for genes affiliated with Seminal Vesicle Tumor

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16Gene Ontology
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Cellular components related to Seminal Vesicle Tumor according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1mitochondrial inner membraneGO:0057439.1SDHA, SDHB
2mitochondrial respiratory chain complex IIGO:0057498.8SDHA, SDHB

Biological processes related to Seminal Vesicle Tumor according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1succinate metabolic processGO:0061059.1SDHA, SDHB
2cellular metabolic processGO:0442379.1SDHA, SDHB
3tricarboxylic acid cycleGO:0060999.0SDHA, SDHB
4respiratory electron transport chainGO:0229048.8SDHA, SDHB

Molecular functions related to Seminal Vesicle Tumor according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1succinate dehydrogenase (ubiquinone) activityGO:0081779.1SDHA, SDHB

Products for genes affiliated with Seminal Vesicle Tumor

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Seminal Vesicle Tumor

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet