MCID: SMN006
MIFTS: 24

Seminal Vesicle Tumor malady

Summaries for Seminal Vesicle Tumor

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33MalaCards
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MalaCards: Seminal Vesicle Tumor, also known as tumor of seminal vesicle, is related to small cell carcinoma and adenosarcoma. An important gene associated with Seminal Vesicle Tumor is DIRC2 (disrupted in renal carcinoma 2), and among its related pathways are Carbon metabolism and Citric acid cycle (TCA cycle). The compounds UBIQUINONE-1 and thenoyltrifluoroacetone have been mentioned in the context of this disorder.

Aliases & Classifications for Seminal Vesicle Tumor

Sources:
8Disease Ontology, 10DISEASES, 61UMLS, 57SNOMED-CT, 40NCIt
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Aliases & Descriptions:

seminal vesicle tumor 8 10
tumor of seminal vesicle 8 61
seminal vesicle neoplasm 8


External Ids:

Disease Ontology8 DOID:3855
SNOMED-CT57 236740006
NCIt40 C39908

Related Diseases for Seminal Vesicle Tumor

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17GeneCards, 18GeneDecks
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Diseases related to Seminal Vesicle Tumor via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 12)
idRelated DiseaseScoreTop Affiliating Genes
1small cell carcinoma10.3
2adenosarcoma10.3
3chromophobe renal cell carcinoma10.3
4carney triad10.0SDHB
5hereditary paraganglioma-pheochromocytoma syndromes10.0SDHB
6chondroma10.0SDHB
7von hippel-lindau disease10.0SDHB
8leigh disease10.0SDHA, SDHB
9paraganglioma10.0SDHB, SDHA
10pheochromocytoma10.0SDHB, SDHA
11hyperthyroidism10.0SDHB, SDHA
12gastrointestinal stromal tumor10.0SDHA, SDHB

Graphical network of diseases related to Seminal Vesicle Tumor:



Diseases related to seminal vesicle tumor

Clinical Features for Seminal Vesicle Tumor

Drugs & Therapeutics for Seminal Vesicle Tumor

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5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Seminal Vesicle Tumor

Anatomical Context for Seminal Vesicle Tumor

Animal Models for Seminal Vesicle Tumor or affiliated genes

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28inGenious Targeting Laboratory
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Publications for Seminal Vesicle Tumor

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51PubMed
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Articles related to Seminal Vesicle Tumor:

(show all 11)
idTitleAuthorsYear
1
Radiology-pathology conference: malignant solitary fibrous tumor of the seminal vesicle. (23466005)
2013
2
Recurrent mullerian adenosarcoma like tumor of seminal vesicle. (20551553)
2010
3
Peripheral primitive neuroectodermal tumor arising from the seminal vesicle. (18362495)
2008
4
Epithelial-stromal tumor of seminal vesicle in a patient with chromophobe renal cell carcinoma and small lymphocytic lymphoma. (18995209)
2008
5
Primary myxoid solitary fibrous tumor involving the seminal vesicle. (16984624)
2006
6
Epithelial-stromal tumor of the seminal vesicles in the transgenic adenocarcinoma mouse prostate model. (15872376)
2005
7
Large solitary fibrous tumor of the seminal vesicle. (14624929)
2003
8
Potent inhibition of CD4/TCR-mediated T cell apoptosis by a CD4-binding glycoprotein secreted from breast tumor and seminal vesicle cells. (10072505)
1999
9
Biosynthesis and immunobiochemical characterization of gp17/GCDFP-15. A glycoprotein from seminal vesicles and from breast tumors, in HeLa cells and in Pichia pastoris yeast. (10504398)
1999
10
Benign peripheral nerve sheath tumor of the seminal vesicle. (9534215)
1998
11
Laparoscopic removal of uterus, seminal vesicle and bilateral ovotestes harboring mature teratoma and carcinoid tumor in an intersex patient. (8618321)
1996

Genetic Variations for Seminal Vesicle Tumor

Expression for genes affiliated with Seminal Vesicle Tumor

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Seminal Vesicle Tumor

Search GEO for disease gene expression data for Seminal Vesicle Tumor.

Pathways for genes affiliated with Seminal Vesicle Tumor

Sources:
30KEGG, 54Reactome, 38NCBI BioSystems Database, 12EMD Millipore
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Pathways related to Seminal Vesicle Tumor according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.1SDHA, SDHB
2
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9.1SDHA, SDHB
3
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9.1SDHA, SDHB
4
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9.1SDHA, SDHB

Compounds for genes affiliated with Seminal Vesicle Tumor

Sources:
11DrugBank, 45Novoseek, 29IUPHAR, 24HMDB
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Compounds related to Seminal Vesicle Tumor according to GeneCards/GeneDecks:

(show all 11)
idCompoundScoreTop Affiliating Genes
1UBIQUINONE-1119.4SDHB, SDHA
2thenoyltrifluoroacetone45 1110.4SDHB, SDHA
32-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol119.3SDHA, SDHB
4succinic acid29 11 2411.3SDHA, SDHB
5iron-sulfur459.3SDHA, SDHB
6ubiquinone459.2SDHA, SDHB
7succinate459.2SDHB, SDHA
8nad+459.1SDHA, SDHB
9iron45 2410.1SDHB, SDHA
10glyceraldehyde 3-phosphate459.0SDHA, SDHB
11nadh45 11 2410.8SDHB, SDHA

GO Terms for genes affiliated with Seminal Vesicle Tumor

Sources:
16Gene Ontology
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Cellular components related to Seminal Vesicle Tumor according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1mitochondrial inner membraneGO:0057439.1SDHA, SDHB
2mitochondrial respiratory chain complex IIGO:0057498.8SDHA, SDHB

Biological processes related to Seminal Vesicle Tumor according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1succinate metabolic processGO:0061059.1SDHA, SDHB
2cellular metabolic processGO:0442379.1SDHA, SDHB
3tricarboxylic acid cycleGO:0060999.0SDHA, SDHB
4respiratory electron transport chainGO:0229048.8SDHA, SDHB

Molecular functions related to Seminal Vesicle Tumor according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1succinate dehydrogenase (ubiquinone) activityGO:0081779.1SDHA, SDHB

Products for genes affiliated with Seminal Vesicle Tumor

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Seminal Vesicle Tumor

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet