Aliases & Classifications for Seminoma

Aliases & Descriptions for Seminoma:

Name: Seminoma 12 52 42 14 69
Seminoma, Pure 12

Classifications:



Summaries for Seminoma

Disease Ontology : 12 A germinoma that has material basis in cells that make sperm and eggs.

MalaCards based summary : Seminoma, also known as seminoma, pure, is related to pneumonia and testis seminoma. An important gene associated with Seminoma is AFP (Alpha Fetoprotein), and among its related pathways/superpathways are Mesenchymal Stem Cell Differentiation Pathways and Lineage-specific Markers and Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors. The drugs Dexamethasone and Paclitaxel have been mentioned in the context of this disorder. Affiliated tissues include testis, lymph node and prostate, and related phenotypes are endocrine/exocrine gland and growth/size/body region

Wikipedia : 71 Seminoma (also known as pure seminoma or classical seminoma) is a germ cell tumor of the testicle or,... more...

Related Diseases for Seminoma

Diseases related to Seminoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 174)
id Related Disease Score Top Affiliating Genes
1 pneumonia 29.2 AFP ALPP ENO2 KIT
2 testis seminoma 12.0
3 testicular seminoma 12.0
4 extragonadal seminoma 12.0
5 testicular spermatocytic seminoma 11.9
6 testicular germ cell tumor 11.9
7 mediastinum seminoma 11.8
8 tubular variant testicular seminoma 11.8
9 cribriform variant testicular seminoma 11.8
10 pseudoglandular variant testicular seminoma 11.8
11 spermatocytoma 11.6
12 embryonal carcinoma 11.3
13 nonseminomatous germ cell tumor 10.8
14 mixed germ cell cancer 10.7
15 renal pelvis transitional cell carcinoma 10.3 AFP CGA
16 pontine hemorrhage 10.3 AFP CGA
17 mood disorder 10.3 AFP KIT
18 true unicornuate uterus 10.3 AFP CGA CGB3
19 anterior optic tract meningioma 10.3 AFP TNFRSF8
20 bagassosis 10.3 AFP CGB3
21 tetrasomy x 10.3 CGA TSPY1
22 orofaciodigital syndrome x 10.3 ALPPL2 KIT TSPY1
23 mediastinitis 10.2
24 nonossifying fibromyxoid tumor 10.2 AFP KIT TNFRSF8
25 severe combined immunodeficiency 10.2 AFP CGA CGB7
26 trypanosomiasis, human east-african 10.2 AFP CGA CGB7
27 fallopian tube leiomyoma 10.2 AFP KIT TNFRSF8
28 subendocardial myocardial infarction 10.2 AFP KIT TNFRSF8
29 parameningeal embryonal rhabdomyosarcoma 10.2 CGA CGB3 CGB7
30 prostate cancer, hereditary, x-linked 1 10.2 AFP ESR2 KIT
31 ophthalmoplegia, progressive, with scrotal tongue and mental deficiency 10.2 AFP CGA INHA
32 nutritional deficiency disease 10.2 AFP TNFRSF8
33 mitral valve disease 10.2 ALPP ENO2
34 painful legs and moving toes syndrome 10.2 ALPP ENO2
35 congenital articular rigidity 10.2 ALPPL2 CGA IGF2
36 pituitary hypoplasia 10.2 ALPP ENO2
37 novak syndrome 10.2 AFP CGB7
38 diabetes mellitus, insulin-resistant, with acanthosis nigricans 10.1 AFP ALPPL2 CGA ESR2
39 infiltrating renal pelvis transitional cell carcinoma 10.1 AFP ENO2
40 gastric leiomyosarcoma 10.1 IGF2 KIT
41 rectum leiomyoma 10.1 AFP ENO2 KIT
42 sphenoid sinus squamous cell carcinoma 10.1 AFP ENO2 KIT
43 glomus tumor 10.1 ENO2 KIT
44 cranial nerve disease 10.1 AFP ENO2 KIT
45 prostate leiomyosarcoma 10.1 IGF2 KIT
46 malignant teratocarcinosarcoma 10.1 AFP ALPP ALPPL2 CGA ESR2
47 ovarian mucinous cystadenocarcinoma 10.1 ALPP ALPPL2 CGA CGB3 CGB7
48 adult teratoma 10.1 AFP ALPP
49 thrombophlebitis 10.1 AFP ENO2
50 cerebral arterial disease 10.1 ENO2 KIT TNFRSF8

Graphical network of the top 20 diseases related to Seminoma:



Diseases related to Seminoma

Symptoms & Phenotypes for Seminoma

MGI Mouse Phenotypes related to Seminoma:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 endocrine/exocrine gland MP:0005379 9.81 NME1 TNFRSF8 AFP CGA ESR2 GJA1
2 growth/size/body region MP:0005378 9.7 ALPPL2 CGA ENO2 ESR2 GJA1 IGF2
3 liver/biliary system MP:0005370 9.17 AFP ESR2 IGF2 INHA KIT NME1

Drugs & Therapeutics for Seminoma

Drugs for Seminoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 134)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dexamethasone Approved, Investigational, Vet_approved Phase 3,Phase 1,Phase 2 50-02-2 5743
2
Paclitaxel Approved, Vet_approved Phase 2, Phase 3, Phase 1 33069-62-4 36314
3
Etoposide Approved Phase 2, Phase 3 33419-42-0 36462
4
Cisplatin Approved Phase 2, Phase 3, Phase 1 15663-27-1 84093 441203 2767
5
Carboplatin Approved Phase 3,Phase 2,Phase 1 41575-94-4 10339178 498142 38904
6
Bleomycin Approved Phase 2, Phase 3 11056-06-7 5360373
7
Ifosfamide Approved Phase 3,Phase 1,Phase 2 3778-73-2 3690
8
Mechlorethamine Approved Phase 3,Phase 1,Phase 2 51-75-2 4033
9
Mesna Approved Phase 3,Phase 1,Phase 2 3375-50-6 598
10
Granisetron Approved, Investigational Phase 3 109889-09-0 3510
11
Lenograstim Approved Phase 2, Phase 3, Phase 1 135968-09-1
12
Cyclophosphamide Approved, Investigational Phase 3 50-18-0, 6055-19-2 2907
13
Captopril Approved Phase 3 62571-86-2 44093
14
Amphotericin B Approved, Investigational Phase 3 1397-89-3 14956 5280965
15
Ribavirin Approved Phase 3 36791-04-5 37542
16
Fluconazole Approved Phase 3 86386-73-4 3365
17
Miconazole Approved, Investigational, Vet_approved Phase 3 22916-47-8 4189
18
Ondansetron Approved Phase 3 99614-02-5 4595
19
Itraconazole Approved, Investigational Phase 3 84625-61-6 55283
20
Palivizumab Approved, Investigational Phase 3 188039-54-5
21
Caspofungin Approved Phase 3 179463-17-3, 162808-62-0 468682 2826718
22
Diphenhydramine Approved Phase 3 58-73-1, 147-24-0 3100
23
Promethazine Approved Phase 3 60-87-7 4927
24
Vinblastine Approved Phase 3 865-21-4 13342 241903
25 Dexamethasone acetate Phase 3,Phase 1,Phase 2 1177-87-3
26 Alkylating Agents Phase 3,Phase 1,Phase 2
27 glucocorticoids Phase 3,Phase 2,Phase 1
28
Serotonin Phase 3 50-67-9 5202
29 Adjuvants, Immunologic Phase 3,Phase 1,Phase 2
30 Serotonin Agents Phase 3
31 Serotonin Antagonists Phase 3
32 Gastrointestinal Agents Phase 3,Phase 2
33 Neurotransmitter Agents Phase 3
34 Albumin-Bound Paclitaxel Phase 2, Phase 3, Phase 1
35 Topoisomerase Inhibitors Phase 2, Phase 3
36 Hormone Antagonists Phase 3,Phase 2,Phase 1
37 Dexamethasone 21-phosphate Phase 3,Phase 1,Phase 2
38 Hormones Phase 3,Phase 2,Phase 1
39 Peripheral Nervous System Agents Phase 3,Phase 2
40 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3,Phase 2,Phase 1
41 Anti-Bacterial Agents Phase 2, Phase 3
42 Etoposide phosphate Phase 2, Phase 3
43 Anti-Infective Agents Phase 3,Phase 1,Phase 2
44 Immunosuppressive Agents Phase 3,Phase 1,Phase 2
45 Antiemetics Phase 3,Phase 2
46 Anti-Inflammatory Agents Phase 3,Phase 2,Phase 1
47 Isophosphamide mustard Phase 3,Phase 1,Phase 2
48 Antimetabolites Phase 3,Phase 1,Phase 2
49 Antibiotics, Antitubercular Phase 2, Phase 3
50 Antimitotic Agents Phase 2, Phase 3, Phase 1

Interventional clinical trials:

(show top 50) (show all 54)
id Name Status NCT ID Phase
1 Magnetic Resonance Imaging and Computed Tomography in Patients With Stage I Seminoma of the Testicle Unknown status NCT00589537 Phase 3
2 Lerisetron Compared With Granisetron in Preventing Nausea and Vomiting in Men Being Treated With Radiation Therapy for Stage I Seminoma Unknown status NCT00004219 Phase 3
3 Combination Chemotherapy in Treating Men With Germ Cell Cancer Unknown status NCT00003643 Phase 2, Phase 3
4 Radiation Therapy Compared With Chemotherapy in Treating Patients With Stage I Testicular Cancer Completed NCT00003014 Phase 3
5 Combination Chemotherapy With or Without Bone Marrow or Stem Cell Transplantation in Treating Men With Untreated Germ Cell Tumors Completed NCT00002596 Phase 3
6 Ribavirin With or Without Monoclonal Antibody Therapy in Treating Patients Who Develop RSV Pneumonia Following Peripheral Stem Cell Transplantation Completed NCT00014391 Phase 3
7 Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment Completed NCT00008359 Phase 3
8 Captopril in Treating Patients Undergoing Bone Marrow or Stem Cell Transplantation Completed NCT00004230 Phase 3
9 Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Men With Previously Untreated Germ Cell Cancer Completed NCT00003941 Phase 3
10 Liposomal Amphotericin B in Treating Granulocytopenia and Persistent Unexplained Fever in Cancer Patients Completed NCT00003938 Phase 3
11 Itraconazole Compared With Fluconazole to Prevent Infections in Patients Undergoing Peripheral Stem Cell or Bone Marrow Transplantation Completed NCT00003883 Phase 3
12 Ondansetron With or Without Dexamethasone to Prevent Vomiting in Patients Receiving Radiation Therapy to the Upper Abdomen Completed NCT00016380 Phase 3
13 Adjuvant Bleomycin, Etoposide and Cisplatin (BEP) Versus Carboplatin in Stage I Seminomatous Testicular Cancer Recruiting NCT02341989 Phase 3
14 Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients With Relapsed or Refractory Germ Cell Tumors Recruiting NCT02375204 Phase 3
15 Cisplatin and Ifosfamide Combined With Either Paclitaxel or Vinblastine in Treating Men With Progressive or Recurrent Metastatic Germ Cell Tumors Terminated NCT00072215 Phase 3
16 A Multi-Centre Phase II Study Using Carboplatin AUC-10 for Metastatic Seminoma With IGCCCG Good Prognosis Disease-Therapy Directed by Initial Metabolic Response on PET-CT Unknown status NCT02272816 Phase 2
17 Gemcitabine, Paclitaxel, Ifosfamide, and Cisplatin in Treating Patients With Progressive or Relapsed Metastatic Germ Cell Tumors Unknown status NCT00551122 Phase 1, Phase 2
18 High-Dose Chemotherapy and Stem Cell Transplant in Treating Patients With Metastatic Germ Cell Tumors That Have Not Responded to First-Line Therapy Unknown status NCT01172912 Phase 2
19 ARQ 197 for Subjects With Relapsed or Refractory Germ Cell Tumors Completed NCT01055067 Phase 2
20 Alvocidib and Oxaliplatin With or Without Fluorouracil and Leucovorin Calcium in Treating Patients With Relapsed or Refractory Germ Cell Tumors Completed NCT00957905 Phase 2
21 Docetaxel in Treating Patients With Recurrent or Refractory Germ Cell Cancer Completed NCT00002903 Phase 2
22 Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Relapsed Germ Cell Cancer Completed NCT00002931 Phase 2
23 Combination Chemotherapy and Pegfilgrastim in Treating Men With Metastatic Germ Cell Tumors Completed NCT00453232 Phase 2
24 Ixabepilone in Treating Patients With Advanced Cisplatin-Refractory Germ Cell Tumors Completed NCT00070096 Phase 2
25 Sunitinib in Treating Patients With Metastatic Germ Cell Tumors That Have Relapsed or Not Responded to Treatment Completed NCT00453310 Phase 2
26 Combination Chemotherapy and Pegfilgrastim in Treating Patients With Previously Untreated Germ Cell Tumors Completed NCT00470366 Phase 2
27 Beclomethasone in Treating Patients With Graft-Versus-Host Disease of the Esophagus, Stomach, Small Intestine, or Colon Completed NCT00010283 Phase 1, Phase 2
28 Interleukin-11 Plus Filgrastim Prior to Peripheral Stem Cell Transplantation in Patients With Non-Hodgkin's Lymphoma, Hodgkin's Disease, Breast Cancer, or Other Solid Tumors Completed NCT00004157 Phase 2
29 Lymphocyte Infusion in Treating Patients With Relapsed Cancer After Bone Marrow or Peripheral Stem Cell Transplantation Completed NCT00003887 Phase 2
30 Biological Therapy Following Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Cancer Completed NCT00003408 Phase 2
31 Immunotherapy in Treating Patients Who Are Undergoing Bone Marrow or Peripheral Stem Cell Transplantation Completed NCT00002673 Phase 2
32 Paclitaxel, Ifosfamide, and Carboplatin Followed By Autologous Stem Cell Transplant in Treating Patients With Germ Cell Tumors That Did Not Respond to Cisplatin Completed NCT00423852 Phase 1, Phase 2
33 Phase II Study of Imatinib Mesylate in Patients With Life Threatening Malignant Rare Diseases Completed NCT00154388 Phase 2
34 Therapy De-escalation in Seminoma Stage IIA/B Recruiting NCT01593241 Phase 2
35 Therapeutic Strategy Guided by PET-TDM for Patients With Seminoma Recruiting NCT01887340 Phase 2
36 Evaluating Immune Therapy, Duravalumab (MEDI4736) With Tremelimumab for Relapsed/Refractory Germ Cell Tumors Recruiting NCT03158064 Phase 2
37 PHASE II TRIAL OF THE CYCLIN-DEPEDENT KINASE INHIBITOR PD 0332991 IN PATIENTS WITH CANCER Recruiting NCT01037790 Phase 2
38 Nivolumab and Ipilimumab in Treating Patients With Rare Tumors Recruiting NCT02834013 Phase 2
39 Autologous Peripheral Blood Stem Cell Transplant for Germ Cell Tumors Recruiting NCT00432094 Phase 2
40 Proton Radiotherapy for Stage I, IIA, and IIB Seminoma Active, not recruiting NCT01557790 Phase 2
41 Imatinib Mesylate in Treating Patients With Progressive, Refractory, or Recurrent Stage II or Stage III Testicular or Ovarian Cancer Terminated NCT00042952 Phase 2
42 Palifosfamide in Treating Patients With Recurrent Germ Cell Tumors Terminated NCT01808534 Phase 2
43 Ipilimumab After Allogeneic Stem Cell Transplant in Treating Patients With Persistent or Progressive Cancer Completed NCT00060372 Phase 1
44 Interleukin-12 in Treating Patients With Hematologic Cancers or Solid Tumors Completed NCT00003107 Phase 1
45 Lapatinib and Paclitaxel in Treating Patients With Advanced Solid Tumors Completed NCT00313599 Phase 1
46 Cardiac Function and Cardiovascular Risk Profile in Testicular Cancer Patients Completed NCT00705094
47 REtrospective Study of TESTIcular CAncer Patients at the University Magdeburg Completed NCT02092740
48 Positron Emission Tomography in Detecting Testicle Cancer Completed NCT00045045
49 Acupuncture in Treating Mucositis-Related Pain Caused by Chemotherapy in Patients Undergoing Stem Cell Transplantation Completed NCT00060021
50 Standard Follow-up Compared With Extended Follow-up in Treating Patients Who Have Undergone Stem Cell Transplantation for Cancer Completed NCT00049465

Search NIH Clinical Center for Seminoma

Cochrane evidence based reviews: seminoma

Genetic Tests for Seminoma

Anatomical Context for Seminoma

MalaCards organs/tissues related to Seminoma:

39
Testis, Lymph Node, Prostate, Kidney, Testes, Bone, Liver

Publications for Seminoma

Articles related to Seminoma:

(show top 50) (show all 840)
id Title Authors Year
1
Mediastinal seminoma associated with multilocular thymic cyst. ( 28054283 )
2017
2
Spermatocytic Seminoma with Brain Metastasis. ( 27815811 )
2017
3
DNA hypomethylation and aberrant expression of the human endogenous retrovirus ERVWE1/syncytin-1 in seminomas. ( 28302141 )
2017
4
Outcome of Men With Relapse After Adjuvant Carboplatin for Clinical Stage I Seminoma. ( 27893332 )
2017
5
Anaplastic lymphoma kinase positive large B-cell lymphoma: Literature review and report of an endoscopic fine needle aspiration case with tigroid backgrounds mimicking seminoma. ( 27686567 )
2017
6
Radiotherapy Alone for Malignant Spinal Cord Compression in Young Men with Seminoma. ( 27069198 )
2016
7
Surveillance versus adjuvant radiotherapy for patients with high-risk stage I seminoma. ( 27893934 )
2016
8
Salvage High-Dose Chemotherapy for Relapsed Pure Seminoma in the Last 10 Years: Results From the European Society for Blood and Marrow Transplantation Series 2002-2012. ( 27444987 )
2016
9
Best treatment option for clinical stage I seminoma patients. ( 27123324 )
2016
10
Is the Wnt/I^ catenin signalling pathway activated in Seminoma?: An immunohistochemical study. ( 27461702 )
2016
11
TDRG1 functions in testicular seminoma are dependent on the PI3K/Akt/mTOR signaling pathway. ( 26855590 )
2016
12
Testicular seminoma clinical stage 1: treatment outcome on a routine care level. ( 27116691 )
2016
13
Is percent seminoma associated with intraoperative morbidity during post-chemotherapy RPLND? ( 26892052 )
2016
14
Metachronous testicular seminoma after radiotherapy and chemotherapy: a case report. ( 27184033 )
2016
15
Nonpalpable testicular pure seminoma with elevated serum alpha-fetoprotein presenting with retroperitoneal metastasis: a case report. ( 27150447 )
2016
16
Testicular Seminoma Occurring After Kidney Transplantation in a Patient Previously Treated for Teratoma: De Novo Malignancy or Recurrence in a Different Histologic Form? ( 27932163 )
2016
17
The challenge to one course Carboplatin in seminoma clinical stage 1. ( 27154420 )
2016
18
Testicular Seminoma With Pseudocyst and Coagulation Necrosis Like Burned-out Tumor: A Case Report. ( 27335779 )
2016
19
Colon Obstruction as an Isolated Late Gastrointestinal Metastasis of Testicular Seminoma. ( 27678015 )
2016
20
Diffuse type testicular seminoma in a stallion. ( 27818621 )
2016
21
mTOR expression in human testicular seminoma. ( 26648340 )
2016
22
The diagnostic yield of fluorine-18 fluorodeoxyglucose positron emission tomography-computed tomography in recurrent testicular seminoma. ( 28058002 )
2016
23
SOX2 is essential for in vivo reprogramming of seminoma-like TCam-2 cells to an embryonal carcinoma-like fate. ( 27283990 )
2016
24
Long-term outcomes following post-operative radiotherapy for Stage I/II testicular seminoma - an Australasian single-institution experience. ( 27648280 )
2016
25
Management and outcomes of clinical stage IIA/B seminoma: Results from the National Cancer Data Base 1998-2012. ( 27345128 )
2016
26
"Hockey Stick" may Strike Back: Hepatocellular Carcinoma on Noncirrhotic Liver as a Late Toxicity of Lombo-Aortic Radiotherapy for Seminoma. A Review Triggered by an Unusual Case. ( 27194897 )
2016
27
Pure Stage I Seminoma with an Elevated hCG of 25,265A mIU/ml: A Case Report. ( 27713862 )
2016
28
Treatment of stage I seminoma, with one course of adjuvant carboplatin or surveillance, risk-adapted recommendations implementing patient autonomy: a report from the Swedish and Norwegian Testicular Cancer Group (SWENOTECA). ( 27052649 )
2016
29
Mechanism and Role of SOX2 Repression in Seminoma: Relevance to Human Germline Specification. ( 27132888 )
2016
30
Nuclear Protein of the Testis Midline Carcinoma Masquerading as a Primary Mediastinal Seminoma. ( 27441078 )
2016
31
Analysis of the prognosis of patients with testicular seminoma. ( 26893743 )
2016
32
Isolated metastasis of testicular seminoma to extralobar pulmonary sequestration. ( 26744493 )
2016
33
OCT4 staining increases the detection of lymphatic/vascular invasion in pure seminoma of the testis obscured by prominent lymphohistiocytic inflammation. ( 27020494 )
2016
34
Intraoperative Molecular Imaging for Post-Chemotherapy Robot-Assisted Laparoscopic Resection of Seminoma Metastasis: A Case Report. ( 27793611 )
2016
35
Primary thymic mediastinal seminoma with florid granulomatous reaction. ( 27510675 )
2016
36
Clinical Characteristics and Outcomes of Late Relapse in Stage I Testicular Seminoma. ( 27339401 )
2016
37
Adjuvant radiation therapy in stage I seminoma: 20 years of oncologic results. ( 27556300 )
2016
38
Differences in global DNA methylation of testicular seminoma are not associated with changes in histone modifications, clinical prognosis, BRAF mutations or gene expression. ( 27886677 )
2016
39
Controversies in the management of clinical stage I testicular seminoma. ( 27123323 )
2016
40
Re: Management Trends in Stage I Testicular Seminoma: Impact of Race, Insurance Status, and Treatment Facility. ( 26852980 )
2016
41
Retraction Note to: Canine transmissible venereal tumor and seminoma: a cytohistopathology and chemotherapy study of tumors in the growth phase and during regression after chemotherapy. ( 27817085 )
2016
42
Complete androgen insensitivity syndrome with concomitant seminoma and Sertoli cell adenoma: an unusual combination. ( 28039344 )
2016
43
Seminoma accompanying mature teratoma in an infantile mediastinal region: A rare presentation of infantile germ cell tumors. ( 27450779 )
2016
44
Giant seminoma in an undescended testicle metastasizing to the neck and liver. ( 27284433 )
2016
45
Stage II Testicular Seminoma: Patterns of Care and Survival by Treatment Strategy. ( 27146264 )
2016
46
Primary retroperitoneal seminoma - embryology, histopathology and treatment particularities. ( 28002522 )
2016
47
Giant primary retroperitoneal seminoma: A case report. ( 27071291 )
2016
48
Testicular seminoma metastasis to duodenum. Misdiagnosed as primary duodenal tumor. ( 27372029 )
2016
49
Reply to "The challenge to one course Carboplatin in seminoma clinical stage 1" by Dieckmann and Anheuser. ( 27177862 )
2016
50
The Evolving Management of Patients With Clinical Stage I Seminoma. ( 27527410 )
2016

Variations for Seminoma

Copy number variations for Seminoma from CNVD:

7 (show all 13)
id CNVD ID Chromosom Start End Type Gene Symbol CNVD Disease
1 55928 11 56400000 134452384 Loss Seminomas
2 61576 12 1 56300000 Gain Seminomas
3 119165 18 1 15400000 Loss Seminomas
4 120979 18 35500000 76117153 Loss Seminomas
5 138723 2 169500000 182700000 Gain Seminomas
6 146936 2 56300000 182700000 Loss Seminomas
7 157118 21 12300000 46944323 Gain Seminomas
8 160299 22 11800000 49691432 Loss Seminomas
9 217037 7 1 158821424 Gain Seminomas
10 237233 8 2200000 146274826 Gain Seminomas
11 257126 X 1 24900000 Gain Seminomas
12 262546 X 37500000 154913754 Gain Seminomas
13 262571 X 37500000 47300000 Gain Seminomas

Expression for Seminoma

Search GEO for disease gene expression data for Seminoma.

GO Terms for Seminoma

Cellular components related to Seminoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.28 AFP ALPPL2 CGA CGB3 CGB7 ESR2

Biological processes related to Seminoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 signal transduction GO:0007165 9.61 CGA CGB3 CGB7 ESR2 GJA1 INHA
2 peptide hormone processing GO:0016486 9.26 CGA CGB3
3 female gamete generation GO:0007292 9.16 CGB3 CGB7
4 cell-cell signaling GO:0007267 9.1 CGA CGB3 CGB7 ESR2 GJA1 INHA

Molecular functions related to Seminoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 9.02 CGA CGB3 CGB7 IGF2 INHA
2 alkaline phosphatase activity GO:0004035 8.96 ALPP ALPPL2

Sources for Seminoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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