MCID: SNS001
MIFTS: 57

Sensorineural Hearing Loss malady

Categories: Ear diseases

Aliases & Classifications for Sensorineural Hearing Loss

Aliases & Descriptions for Sensorineural Hearing Loss:

Name: Sensorineural Hearing Loss 12 29 14 69
Sensory Hearing Loss 12 52 69
Hearing Loss, High-Frequency 42 69
Hearing Loss, Central 42 69
Perceptive Hearing Loss or Deafness 12
High Frequency Hearing Loss 12
High-Frequency Hearing Loss 12
Hearing Loss High-Frequency 52
Hearing Loss, Sensorineural 42
Hearing Loss Sensorineural 52
High Frequency Deafness 12
Perceptive Hearing Loss 12
Sensorineural Deafness 12
Deafness Sensorineural 52
Central Hearing Loss 12
Perceptive Deafness 12

Classifications:



Summaries for Sensorineural Hearing Loss

MalaCards based summary : Sensorineural Hearing Loss, also known as sensory hearing loss, is related to deafness, autosomal recessive 23 and deafness, autosomal dominant 2a. An important gene associated with Sensorineural Hearing Loss is GJB2 (Gap Junction Protein Beta 2), and among its related pathways/superpathways are Neural Crest Differentiation and Gap junction trafficking. The drugs Silver sulfadiazine and Cisplatin have been mentioned in the context of this disorder. Affiliated tissues include bone, testes and brain, and related phenotypes are Effect on mitosis and hearing/vestibular/ear

Wikipedia : 71 Sensorineural hearing loss (SNHL) is a type of hearing loss, or deafness, in which the root cause lies... more...

Related Diseases for Sensorineural Hearing Loss

Diseases related to Sensorineural Hearing Loss via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 583)
id Related Disease Score Top Affiliating Genes
1 deafness, autosomal recessive 23 32.0 GJB2 MYO7A SLC26A4 WFS1
2 deafness, autosomal dominant 2a 31.9 COCH GJB2 GJB6 KCNQ4 WFS1
3 autosomal recessive nonsyndromic deafness 97 31.7 GJB2 MYH9 MYO6 MYO7A OTOF SLC26A4
4 macrothrombocytopenia and progressive sensorineural deafness 31.4 MYH9 MYO6 MYO7A
5 autosomal dominant nonsyndromic deafness 69 30.2 COCH GJB2 MYO7A OTOF SLC26A4 WFS1
6 mitochondrial non-syndromic sensorineural deafness 29.6 GJB2 GJB3 GJB6 MYH9 MYO6 MYO7A
7 x-linked nonsyndromic deafness 28.6 COCH EYA4 GJB2 GJB3 GJB6 KCNQ4
8 split-hand/foot malformation 1 with sensorineural hearing loss 12.3
9 corneal endothelial dystrophy and perceptive deafness 12.3
10 cataracts, growth hormone deficiency, sensory neuropathy, sensorineural hearing loss, and skeletal dysplasia 12.3
11 sudden sensorineural hearing loss 12.3
12 hypoparathyroidism, sensorineural deafness, and renal dysplasia 12.2
13 cleft palate, midfacial hypoplasia, triangular facies, and sensorineural hearing loss 12.1
14 dfna6/14/38 nonsyndromic low frequency sensorineural hearing loss 12.0
15 nonsyndromic hereditary sensorineural hearing loss 12.0
16 hypogonadotropic hypogonadism-severe microcephaly-sensorineural hearing loss-dysmorphism syndrome 12.0
17 ectodermal dysplasia, sensorineural hearing loss, and distinctive facial features 12.0
18 autosomal dominant myopia-midfacial retrusion-sensorineural hearing loss-rhizomelic dysplasia syndrome 12.0
19 sensorineural hearing loss-early graying-essential tremor syndrome 12.0
20 bjornstad syndrome 11.8
21 capos syndrome 11.8
22 deafness, autosomal dominant 22 11.7
23 deafness, autosomal dominant 1 11.7
24 deafness, x-linked 2 11.7
25 fibromatosis, gingival, with progressive deafness 11.7
26 cardiomyopathy, dilated, 1j 11.7
27 heimler syndrome 1 11.6
28 alport syndrome, autosomal dominant 11.5
29 epilepsy, hearing loss, and mental retardation syndrome 11.5
30 lichtenstein-knorr syndrome 11.5
31 neuropathy, hereditary sensory, type ie 11.5
32 hereditary sensory and autonomic neuropathy type 1e 11.5
33 x-linked non-syndromic sensorineural deafness type dfn 11.5
34 autosomal dominant non-syndromic sensorineural deafness type dfna 11.5
35 pendred syndrome 11.4
36 deafness, autosomal recessive 48 11.3
37 deafness, autosomal recessive 9 11.3
38 deafness, autosomal dominant 41 11.3
39 deafness, autosomal dominant 56 11.3
40 deafness, autosomal recessive 36 11.3
41 mondini dysplasia 11.2
42 epstein syndrome 11.2
43 perrault syndrome 11.2
44 axenfeld-rieger syndrome, type 3 11.2
45 deafness, autosomal recessive 88 11.2
46 deafness and myopia 11.1
47 deafness, autosomal dominant 67 11.1
48 deafness, autosomal recessive 12 11.1
49 deafness, autosomal dominant 40 11.1
50 deafness, autosomal recessive 91 11.1

Comorbidity relations with Sensorineural Hearing Loss via Phenotypic Disease Network (PDN):


Acute Cystitis Deficiency Anemia
Heart Disease Hypertension, Essential
Schizophreniform Disorder

Graphical network of the top 20 diseases related to Sensorineural Hearing Loss:



Diseases related to Sensorineural Hearing Loss

Symptoms & Phenotypes for Sensorineural Hearing Loss

GenomeRNAi Phenotypes related to Sensorineural Hearing Loss according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Effect on mitosis GR00257-A-2 9.02 COCH DLX5 EYA4 GJB3 MYH9

MGI Mouse Phenotypes related to Sensorineural Hearing Loss:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hearing/vestibular/ear MP:0005377 10.22 ATP6V1B1 COCH COL2A1 DLX5 EYA4 GJB2
2 behavior/neurological MP:0005386 10.11 ATP6V1B1 COL2A1 DLX5 GJB6 MITF MYO6
3 homeostasis/metabolism MP:0005376 10.03 ATP6V1B1 COL2A1 COL4A5 EYA4 GJB2 GJB3
4 nervous system MP:0003631 9.97 MYO7A OTOF SLC26A4 TMC1 USH2A COL2A1
5 no phenotypic analysis MP:0003012 9.56 GJB2 GJB3 GJB6 MITF MYH9 MYO7A
6 vision/eye MP:0005391 9.23 MYH9 MYO6 MYO7A USH2A COL2A1 COL4A5

Drugs & Therapeutics for Sensorineural Hearing Loss

Drugs for Sensorineural Hearing Loss (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 387)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Silver sulfadiazine Approved, Vet_approved Phase 4 22199-08-2 441244
2
Cisplatin Approved Phase 4,Phase 3,Phase 2,Phase 1 15663-27-1 84093 441203 2767
3
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 50-02-2 5743
4
Carboplatin Approved Phase 4,Phase 1,Phase 2 41575-94-4 10339178 498142 38904
5
Vincristine Approved, Investigational Phase 4,Phase 3,Phase 2 2068-78-2, 57-22-7 5978
6
Menthol Approved Phase 4,Phase 3 2216-51-5 16666
7
Lansoprazole Approved, Investigational Phase 4 103577-45-3 3883
8
Acetaminophen Approved Phase 4,Phase 3 103-90-2 1983
9
Cefotaxime Approved Phase 4 63527-52-6 456256 5742673
10
Cefoxitin Approved Phase 4 35607-66-0 441199
11
Alprazolam Approved, Illicit, Investigational Phase 4 28981-97-7 2118
12
Dopamine Approved Phase 4,Phase 3,Phase 2 51-61-6, 62-31-7 681
13
Acetylcysteine Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 616-91-1 12035
14
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
15
Cyclophosphamide Approved, Investigational Phase 4,Phase 3,Phase 2 50-18-0, 6055-19-2 2907
16
Iron Approved Phase 4,Phase 2,Phase 3,Phase 1 7439-89-6 23925
17
Etoposide Approved Phase 4,Phase 1,Phase 2 33419-42-0 36462
18
Lenograstim Approved Phase 4 135968-09-1
19
Mesna Approved Phase 4 3375-50-6 598
20
Methotrexate Approved Phase 4,Phase 3,Phase 2 1959-05-2, 59-05-2 126941
21
Thiotepa Approved Phase 4,Phase 2 52-24-4 5453
22
Deferiprone Approved Phase 4,Phase 2,Phase 3 30652-11-0 2972
23
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 2,Phase 3 59-30-3 6037
24
Niacin Approved, Investigational, Nutraceutical Phase 4 59-67-6 938
25
Nicotinamide Approved, Nutraceutical Phase 4 98-92-0 936
26
Vitamin E Approved, Nutraceutical, Vet_approved Phase 4,Phase 2 59-02-9 14985
27
Melatonin Approved, Nutraceutical, Vet_approved Phase 4 73-31-4 896
28
leucovorin Approved, Nutraceutical Phase 4,Phase 3,Phase 2 58-05-9 54575, 6560146 143
29 Antiemetics Phase 4,Phase 3,Phase 1,Phase 2
30 Anti-Inflammatory Agents Phase 4,Phase 2,Phase 3,Phase 1
31 Antineoplastic Agents, Hormonal Phase 4,Phase 2,Phase 3,Phase 1
32 Autonomic Agents Phase 4,Phase 3,Phase 2,Phase 1
33 BB 1101 Phase 4,Phase 3,Phase 2
34 Dexamethasone 21-phosphate Phase 4,Phase 3,Phase 2
35 Dexamethasone acetate Phase 4,Phase 3,Phase 2 1177-87-3
36 Gastrointestinal Agents Phase 4,Phase 3,Phase 1,Phase 2
37 glucocorticoids Phase 4,Phase 2,Phase 3,Phase 1
38 HIV Protease Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
39 Hormone Antagonists Phase 4,Phase 2,Phase 3,Phase 1
40 Hormones Phase 4,Phase 2,Phase 3,Phase 1
41 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 2,Phase 3,Phase 1
42 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1
43
protease inhibitors Phase 4,Phase 3,Phase 2,Phase 1
44 Analgesics Phase 4,Phase 3,Phase 2,Phase 1
45 Anti-Bacterial Agents Phase 4,Phase 3,Phase 1,Phase 2
46 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1
47 Antioxidants Phase 4,Phase 3,Phase 2,Phase 1
48 Protective Agents Phase 4,Phase 3,Phase 2,Phase 1
49 Anesthetics Phase 4,Phase 3,Phase 2,Phase 1
50 Central Nervous System Depressants Phase 4,Phase 3,Phase 2

Interventional clinical trials:

(show top 50) (show all 497)
id Name Status NCT ID Phase
1 The Influence of The Ear Popper on Serous Otitis Media and on the Accompanying Conductive Hearing Loss in Children Unknown status NCT00393159 Phase 4
2 Relationship Between Auto NRT and Behavioural T & C Levels With the Nucleus Freedom Cochlear Implant Unknown status NCT00331539 Phase 4
3 Evaluation of Benefit for Treatment of Single Sided Deafness (SSD) Between Two Bone Conduction Prosthetic Devices; Osseointegrated Implant Versus Maxilla Anchored Removable Oral Appliance ("SoundBite") Unknown status NCT01933386 Phase 4
4 Bilateral Cochlear Implant Benefit in Young Children Unknown status NCT00424307 Phase 4
5 Evaluation of the Effectiveness of Bone-anchored Hearing Aids (Baha) Unknown status NCT01264510 Phase 4
6 Prevention of Cisplatin-Induced Hearing Loss by Intratympanic Dexamethasone Treatment Completed NCT01372904 Phase 4
7 The Esteem® Hearing Implant Post Approval Study Completed NCT02666222 Phase 4
8 What Needle Diameter Should Physician Use When They Perform Lumbar Puncture ? A Randomized Controlled Trial Completed NCT01481922 Phase 4
9 Maternal Music Exposure During Pregnancy Influences Neonatal Behaviour Completed NCT01278329 Phase 4
10 Study of Anti-reflux Medication as a Potential Treatment for Glue Ear in Children Completed NCT01082029 Phase 4
11 Bilateral Benefit in Adult Users of the HiRes 90K Bionic Ear System Completed NCT00205881 Phase 4
12 Slow Initial β-lactam Infusion With High-dose Paracetamol to Improve the Outcomes of Childhood Bacterial Meningitis Completed NCT01540838 Phase 4
13 Effect of Stellate Ganglion Block on Meniere's Disease Completed NCT01574313 Phase 4
14 Taste, Smell and Chemotherapy (TASTY) Completed NCT01641172 Phase 4
15 Premedication With Melatonin and Alprazolam Combination Versus Alprazolam or Melatonin Alone Completed NCT01486615 Phase 4
16 Long-Term Growth and Skeletal Effects of Early Growth Hormone Treatment in Turner Syndrome Completed NCT00266656 Phase 4
17 Efficacy of Acetylcysteine in Patients Undergoing Surgery for Otosclerosis Completed NCT00525551 Phase 4
18 Diaphragmatic Movement Before and After Stellate Ganglion Block : A Ultrasonographic Study Completed NCT01054378 Phase 4
19 HeadStart4: Newly Diagnosed Children (<10 y/o) With Medulloblastoma and Other CNS Embryonal Tumors Recruiting NCT02875314 Phase 4
20 Observational Study of Deferiprone (Ferriprox®) in the Treatment of Superficial Siderosis Active, not recruiting NCT01284127 Phase 4
21 Bed Rest for Idiopathic Sudden Sensorineural Hearing Loss Unknown status NCT00416143 Phase 2, Phase 3
22 Congenital Cytomegalovirus: Efficacy of Antiviral Treatment Unknown status NCT02005822 Phase 3
23 Cisplatin With or Without Sodium Thiosulfate in Treating Young Patients With Stage I, Stage II, or Stage III Childhood Liver Cancer Unknown status NCT00652132 Phase 3
24 Radiation Therapy Plus Combination Chemotherapy in Treating Children With Medulloblastoma Unknown status NCT00053872 Phase 3
25 Efficacy Study of Hypothermia Plus Magnesium Sulphate(MgSO4) in the Management of Term and Near Term Babies With Hypoxic Ischemic Encephalopathy Unknown status NCT01646619 Phase 3
26 SCIPA (Spinal Cord Injury and Physical Activity) Hands-On: Early Intensive Hand Rehabilitation After Spinal Cord Injury Unknown status NCT01086930 Phase 3
27 Intensity-Modulated Radiation Therapy or 3-Dimensional Conformal Radiation Therapy in Decreasing Hearing Loss in Patients Who Have Undergone Surgery for Parotid Tumors Unknown status NCT01216800 Phase 3
28 Efficacy of Antiviral Medications in Controlling Vertigo Attacks of Patients With Meniere's Disease Unknown status NCT01729767 Phase 2, Phase 3
29 Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy Completed NCT00716976 Phase 3
30 Trial of Aggressive Versus Conservative Phototherapy in Infants <1,000 Grams Birth Weight Completed NCT00114543 Phase 3
31 Alpha-Lipoic Acid in Preventing Hearing Loss in Cancer Patients Undergoing Treatment With Cisplatin Completed NCT00477607 Phase 2, Phase 3
32 Aminophylline for Patients With Post-Dural Puncture Headache Completed NCT02522013 Phase 3
33 Oral Glycerol and High-Dose Rectal Paracetamol to Improve the Prognosis of Childhood Bacterial Meningitis Completed NCT00619203 Phase 3
34 Betaine and Peroxisome Biogenesis Disorders Completed NCT01838941 Phase 3
35 Tinnitus Retraining Therapy Trial Completed NCT01177137 Phase 3
36 Pamidronate to Treat Osteogenesis Imperfecta in Children Completed NCT00005901 Phase 3
37 Somatropin Treatment to Final Height in Turner Syndrome Completed NCT00191113 Phase 3
38 Fibrin Monomer Compared With Hemostatic Sponge in the Integrity of the Graft During Tympanoplasty Completed NCT02120651 Phase 3
39 Combining Exercise and Cognitive Training to Improve Everyday Function Completed NCT01603784 Phase 3
40 Sudden Deafness Treatment Trial Completed NCT00097448 Phase 3
41 Premature Infants in Need of Transfusion (PINT) Completed NCT00182390 Phase 3
42 Short-Term vs. Long-Term Valganciclovir Therapy for Symptomatic Congenital CMV Infections Completed NCT00466817 Phase 3
43 Efficacy and Safety Study of Canakinumab Administered for 6 Months (24 Weeks) in Japanese Patients With Cryopyrin-associated Periodic Syndromes Followed by an Extension Phase Completed NCT00991146 Phase 3
44 Secretin for the Treatment of Autism Completed NCT00065962 Phase 3
45 Xylitol Syrup for the Prevention of Acute Otitis Media in Otitis-prone Children Completed NCT01044030 Phase 3
46 Acyclovir for Herpes Infections Involving the Central Nervous System in Neonates Completed NCT00031460 Phase 3
47 Comparison of Radiation Therapy Regimens in Combination With Chemotherapy in Treating Young Patients With Newly Diagnosed Standard-Risk Medulloblastoma Completed NCT00085735 Phase 3
48 Long-Term Efficacy and Safety of Asenapine Using Haloperidol as a Positive Control (41513)(COMPLETED)(P05785) Completed NCT00156065 Phase 3
49 Efficacy and Safety of Hydrocodone Bitartrate Extended-Release Tablets for Moderate to Severe Chronic Low Back Pain Completed NCT01789970 Phase 3
50 Open-Label, Extension Study to Evaluate the Safety of Hydrocodone Bitartrate Extended-Release Tablets Completed NCT01922739 Phase 3

Search NIH Clinical Center for Sensorineural Hearing Loss

Cochrane evidence based reviews: hearing loss, central

Genetic Tests for Sensorineural Hearing Loss

Genetic tests related to Sensorineural Hearing Loss:

id Genetic test Affiliating Genes
1 Sensorineural Hearing Loss 29

Anatomical Context for Sensorineural Hearing Loss

MalaCards organs/tissues related to Sensorineural Hearing Loss:

39
Bone, Testes, Brain, Endothelial, Neutrophil, Heart, Myeloid

Publications for Sensorineural Hearing Loss

Articles related to Sensorineural Hearing Loss:

(show top 50) (show all 960)
id Title Authors Year
1
Prognostic Factors for Recovery from Sudden Sensorineural Hearing Loss: A Retrospective Study. ( 28417102 )
2017
2
The Relationship Between Iron Deficiency Anemia and Sensorineural Hearing Loss in the Pediatric and Adolescent Population. ( 28492865 )
2017
3
Degeneration of auditory nerve fibers in guinea pigs with severe sensorineural hearing loss. ( 28087418 )
2017
4
Sealing of the round and oval window niches with triamcinolone-soaked fascia as salvage surgical therapy in sudden sensorineural hearing loss. ( 28415914 )
2017
5
Assessing Sensorineural Hearing Loss Using Various Transient-Evoked Otoacoustic Emission Stimulus Conditions. ( 28437273 )
2017
6
First report of prevalence c.IVS1+1G>A and del (GJB6-13S1854) mutations in Syrian families with non-syndromic sensorineural hearing loss. ( 28012540 )
2017
7
Assessment of balance and vestibular functions in patients with idiopathic sudden sensorineural hearing loss. ( 28397037 )
2017
8
A sustained increase of plasma fibrinogen in sudden sensorineural hearing loss predicts worse outcome independently. ( 28502595 )
2017
9
Factors Prognostic of Season-Associated Sudden Sensorineural Hearing Loss: A Retrospective Observational Study. ( 28417108 )
2017
10
Cochlear Homocysteine Metabolism at the Crossroad of Nutrition and Sensorineural Hearing Loss. ( 28487633 )
2017
11
Prognostic factors for idiopathic sudden sensorineural hearing loss treated with hyperbaric oxygen therapy and intravenous steroids. ( 27917721 )
2017
12
High prevalence of abnormalities on CT and MR imaging in children with unilateral sensorineural hearing loss irrespective of age or degree of hearing loss. ( 28483233 )
2017
13
A common variant in CLDN14 causes precipitous, prelingual sensorineural hearing loss in multiple families due to founder effect. ( 27838790 )
2017
14
Intratympanic steroid delivery by an indwelling catheter in refractory severe sudden sensorineural hearing loss. ( 28511890 )
2017
15
Biochemical alteration in children with idiopathic nephrotic syndrome associated with an increased risk of sensorineural hearing loss; additional insights in cochlear renal relationship. ( 28483237 )
2017
16
Cochlear synaptopathy in acquired sensorineural hearing loss: Manifestations and mechanisms. ( 28087419 )
2017
17
Cytokine gene polymorphism associations with congenital cytomegalovirus infection and sensorineural hearing loss. ( 28501927 )
2017
18
Anisomorphic Cortical Reorganization in Asymmetric Sensorineural Hearing Loss. ( 28515283 )
2017
19
Interrupted Monosyllabic Words: The Effects of Ten Interruption Locations on Recognition Performance by Older Listeners with Sensorineural Hearing Loss. ( 28054913 )
2017
20
Hyperbaric Oxygen Therapy as Adjuvant Treatment for Idiopathic Sudden Sensorineural Hearing Loss after Failure of Systemic Steroids. ( 28423374 )
2017
21
Framingham Risk Score as a Prognostic Predictor of Sudden Sensorineural Hearing Loss: A Preliminary Study. ( 28397567 )
2017
22
Resolution of giant basilar artery aneurysm compression and reversal of sensorineural hearing loss with use of a flow diverter: case report. ( 28452658 )
2017
23
Diffusion Kurtosis Imaging of Microstructural Alterations in the Brains of Paediatric Patients with Congenital Sensorineural Hearing Loss. ( 28484279 )
2017
24
Early cortical metabolic rearrangement related to clinical data in idiopathic sudden sensorineural hearing loss. ( 28460253 )
2017
25
Comparative Analysis of the Combined Therapeutic Effects of Lipoprostaglandin E1 on Sudden Idiopathic Sensorineural Hearing Loss. ( 28417106 )
2017
26
Sensorineural hearing loss in patients with chronic suppurative otitis media: Is there a significant correlation? ( 28465813 )
2017
27
Genetic Basis of Nonsyndromic Sensorineural Hearing Loss in the Sub-Saharan African Island Population of SALo TomAc and PrA-ncipe: The Role of the DFNB1 Locus? ( 27501294 )
2016
28
Prognostic Factors in Sudden Sensorineural Hearing Loss. ( 26966623 )
2016
29
Novel compound heterozygous mutations in MYO7A gene associated with autosomal recessive sensorineural hearing loss in a Chinese family. ( 26968074 )
2016
30
A mismatch negativity study in Mandarin-speaking children with sensorineural hearing loss. ( 27863627 )
2016
31
The neutrophil-to-lymphocyte ratio in children with sudden sensorineural hearing loss: a retrospective study. ( 27598228 )
2016
32
Diagnosis and Management of Congenital Sensorineural Hearing Loss. ( 28083467 )
2016
33
Risk of sudden sensorineural hearing loss in stroke patients: A 5-year nationwide investigation of 44,460 patients. ( 27603402 )
2016
34
Pediatric sudden sensorineural hearing loss: Etiology, diagnosis and treatment in 20 children. ( 27497416 )
2016
35
The combination of vestibular impairment and congenital sensorineural hearing loss predisposes patients to ocular anomalies, including Usher syndrome. ( 27743452 )
2016
36
Cochlear implantation in autistic children with profound sensorineural hearing loss. ( 27939998 )
2016
37
Modeling the Effects of Sensorineural Hearing Loss on Sound Localization in the Median Plane. ( 27659486 )
2016
38
The clinical analysis of bilateral successive sudden sensorineural hearing loss. ( 27052547 )
2016
39
Clinical Predictors of Sensorineural Hearing Loss and Cognitive Outcome in Infants with Symptomatic Congenital Cytomegalovirus Infection. ( 27195603 )
2016
40
Clinical Study on 136 Children with Sudden Sensorineural Hearing Loss. ( 27064040 )
2016
41
Ethics of Placebo Control in Trials for Idiopathic Sudden Sensorineural Hearing Loss: Counterpoint. ( 27371620 )
2016
42
Risk of sudden sensorineural hearing loss in patients with end-stage renal disease undergoing dialysis. ( 27082416 )
2016
43
Combined intratympanic and systemic use of steroids for idiopathic sudden sensorineural hearing loss: a meta-analysis. ( 27071771 )
2016
44
Does Herpes Virus Reactivation Affect Prognosis in Idiopathic Sudden Sensorineural Hearing Loss? ( 27459199 )
2016
45
Is hyperbaric oxygen therapy a salvage treatment option for sudden sensorineural hearing loss? ( 27572676 )
2016
46
SLC26A4 genotypes associated with enlarged vestibular aqueduct malformation in south Italian children with sensorineural hearing loss. ( 26894580 )
2016
47
Regenerative efficacy of mesenchymal stromal cells from human placenta in sensorineural hearing loss. ( 27863646 )
2016
48
Successful continual intratympanic steroid injection therapy in a patient with refractory sensorineural hearing loss accompanied by relapsing polychondritis. ( 27552828 )
2016
49
Establishment of a Flexible Real-Time Polymerase Chain Reaction-Based Platform for Detecting Prevalent Deafness Mutations Associated with Variable Degree of Sensorineural Hearing Loss in Koreans. ( 27583405 )
2016
50
Sudden sensorineural hearing loss: Is there a connection with inner ear electrolytic disorders? A literature review. ( 27895287 )
2016

Variations for Sensorineural Hearing Loss

Copy number variations for Sensorineural Hearing Loss from CNVD:

7 (show all 13)
id CNVD ID Chromosom Start End Type Gene Symbol CNVD Disease
1 115500 17 58121080 60118579 Deletion Sensorineural hearing loss
2 115503 17 58121080 60118579 Deletion APPBP2 sensorineural hearing loss
3 115507 17 58121080 60118579 Deletion BCAS3 sensorineural hearing loss
4 115511 17 58121080 60118579 Deletion BRIP1 sensorineural hearing loss
5 115515 17 58121080 60118579 Deletion CA4 sensorineural hearing loss
6 115519 17 58121080 60118579 Deletion INTS2 sensorineural hearing loss
7 115523 17 58121080 60118579 Deletion MED13 sensorineural hearing loss
8 115527 17 58121080 60118579 Deletion NACA2 sensorineural hearing loss
9 115531 17 58121080 60118579 Deletion PPM1D sensorineural hearing loss
10 115535 17 58121080 60118579 Deletion TBX2 sensorineural hearing loss
11 115539 17 58121080 60118579 Deletion TBX4 sensorineural hearing loss
12 115543 17 58121080 60118579 Deletion USP32 sensorineural hearing loss
13 115552 17 58172730 60315273 Deletion Sensorineural hearing loss

Expression for Sensorineural Hearing Loss

Search GEO for disease gene expression data for Sensorineural Hearing Loss.

Pathways for Sensorineural Hearing Loss

Pathways related to Sensorineural Hearing Loss according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 11.14 COL2A1 DLX5 MITF
2
Show member pathways
10.92 GJB2 GJB3 GJB6 MYO6

GO Terms for Sensorineural Hearing Loss

Cellular components related to Sensorineural Hearing Loss according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 apical plasma membrane GO:0016324 9.55 ATP6V1B1 GJB6 MYO7A SLC26A4 USH2A
2 basement membrane GO:0005604 9.54 COL2A1 COL4A5 USH2A
3 microvillus GO:0005902 9.5 ATP6V1B1 MYO6 MYO7A
4 myosin complex GO:0016459 9.43 MYH9 MYO6 MYO7A
5 gap junction GO:0005921 9.13 GJB2 GJB3 GJB6
6 connexin complex GO:0005922 8.8 GJB2 GJB3 GJB6

Biological processes related to Sensorineural Hearing Loss according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 visual perception GO:0007601 9.72 COL2A1 EYA4 MYO7A USH2A WFS1
2 ossification GO:0001503 9.63 ATP6V1B1 COL2A1 DLX5
3 inner ear morphogenesis GO:0042472 9.55 ATP6V1B1 COL2A1 DLX5 KCNQ4 MYO7A
4 cell communication GO:0007154 9.54 GJB2 GJB3 GJB6
5 sensory perception of sound GO:0007605 9.5 ATP6V1B1 COCH COL2A1 EYA4 GJB2 GJB6
6 regulation of pH GO:0006885 9.48 ATP6V1B1 SLC26A4
7 sensory perception of light stimulus GO:0050953 9.43 MYO7A USH2A
8 actin filament-based movement GO:0030048 9.43 MYH9 MYO6 MYO7A
9 inner ear receptor cell differentiation GO:0060113 9.4 MYO7A USH2A
10 inner ear development GO:0048839 9.35 COL2A1 EYA4 GJB2 GJB6 MYO7A

Molecular functions related to Sensorineural Hearing Loss according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 motor activity GO:0003774 9.5 MYH9 MYO6 MYO7A
2 microfilament motor activity GO:0000146 9.37 MYH9 MYO7A
3 actin-dependent ATPase activity GO:0030898 9.26 MYH9 MYO7A
4 calmodulin binding GO:0005516 9.26 MYH9 MYO6 MYO7A WFS1
5 gap junction channel activity GO:0005243 9.16 GJB2 GJB3
6 ADP binding GO:0043531 8.8 MYH9 MYO6 MYO7A

Sources for Sensorineural Hearing Loss

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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