MCID: SPS090
MIFTS: 18

Sepsis in Premature Infants malady

Summaries for Sepsis in Premature Infants

Sources:
33MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
MalaCards: Sepsis in Premature Infants is related to sepsis and pyelonephritis. An important gene associated with Sepsis in Premature Infants is CALCA (calcitonin-related polypeptide alpha). The compounds dmsa and pamidronate have been mentioned in the context of this disorder.

Aliases & Classifications for Sepsis in Premature Infants

Sources:
49Orphanet, 26ICD10 via Orphanet
See all sources

Classifications:



Characteristics (Orphanet epidemiological data):

49
sepsis in premature infants:
Prevalence: 1-5/10000


Aliases & Descriptions:

sepsis in premature infants 49


External Ids:

ICD10 via Orphanet26 P36

Related Diseases for Sepsis in Premature Infants

Sources:
17GeneCards, 18GeneDecks
See all sources

Graphical network of the top 20 diseases related to Sepsis in Premature Infants:



Diseases related to sepsis in premature infants

Clinical Features for Sepsis in Premature Infants

Drugs & Therapeutics for Sepsis in Premature Infants

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Sepsis in Premature Infants

Drug clinical trials:

Search ClinicalTrials for Sepsis in Premature Infants

Search NIH Clinical Center for Sepsis in Premature Infants

Search CenterWatch for Sepsis in Premature Infants

Genetic Tests for Sepsis in Premature Infants

Anatomical Context for Sepsis in Premature Infants

Animal Models for Sepsis in Premature Infants or affiliated genes

Sources:
28inGenious Targeting Laboratory
See all sources

Publications for Sepsis in Premature Infants

Sources:
51PubMed
See all sources

Articles related to Sepsis in Premature Infants:

idTitleAuthorsYear
1
Comparison of serum amyloid A concentrations with those of C-reactive protein and procalcitonin in diagnosis and follow-up of neonatal sepsis in premature infants. (19078972)
2009
2
Is urine interleukin-8 level a reliable laboratory test for diagnosing late onset sepsis in premature infants? (17596292)
2007
3
Prevalence of two tumor necrosis factor gene polymorphisms in premature infants with early onset sepsis. (17108674)
2006
4
The effect of neonatal sepsis on bone turnover in very-low birth weight premature infants. (12705367)
2003
5
Premature infants respond to early-onset and late-onset sepsis with leukocyte activation. (10969258)
2000
6
Effect of the immunomodulating agent, pentoxifylline, in the treatment of sepsis in prematurely delivered infants: a placebo-controlled, double-blind trial. (10321674)
1999
7
Pentoxifylline reduces plasma tumour necrosis factor-alpha concentration in premature infants with sepsis. (8741040)
1996

Genetic Variations for Sepsis in Premature Infants

Expression for genes affiliated with Sepsis in Premature Infants

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Sepsis in Premature Infants

Search GEO for disease gene expression data for Sepsis in Premature Infants.

Pathways for genes affiliated with Sepsis in Premature Infants

Compounds for genes affiliated with Sepsis in Premature Infants

Sources:
45Novoseek, 50PharmGKB, 11DrugBank, 29IUPHAR, 60Tocris Bioscience, 24HMDB, 2BitterDB
See all sources

Compounds related to Sepsis in Premature Infants according to GeneCards/GeneDecks:

(show all 18)
idCompoundScoreTop Affiliating Genes
1dmsa459.6CRP, CALCA
2pamidronate45 50 1111.6CRP, CALCA
3tibolone459.6CALCA, CRP
4pmma459.6CALCA, CRP
5deoxypyridinoline459.6CRP, CALCA
625-hydroxyvitamin d459.5CALCA, CRP
7nitroglycerin45 1110.5CALCA, CRP
8azithromycin45 1110.4CRP, IL8
9sulfasalazine45 29 50 1112.4CRP, IL8
10prostaglandin f2alpha459.3CRP, CALCA
118-isoprostane459.3IL8, CRP
12etanercept45 50 1111.2IL8, CRP
13simvastatin45 50 60 29 11 2414.1IL8, CRP
14neopterin459.0IL8, CRP
15methacholine45 119.8IL8, CRP, CALCA
16lactate458.8IL8, CRP, CALCA
17hydrocortisone45 2 60 1111.7IL8, CALCA
18vegf458.6CALCA, CRP, IL8

GO Terms for genes affiliated with Sepsis in Premature Infants

Sources:
16Gene Ontology
See all sources

Cellular components related to Sepsis in Premature Infants according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:0055768.5IL8, CRP, CALCA
2extracellular spaceGO:0056158.2IL8, CRP, CALCA

Biological processes related to Sepsis in Premature Infants according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1agingGO:0075689.3CRP, CALCA
2receptor internalizationGO:0316238.7IL8, CALCA
3inflammatory responseGO:0069548.4IL8, CRP, CALCA

Products for genes affiliated with Sepsis in Premature Infants

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Sepsis in Premature Infants

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet