MCID: SPS090
MIFTS: 21

Sepsis in Premature Infants malady

Categories: Rare diseases

Aliases & Classifications for Sepsis in Premature Infants

Summaries for Sepsis in Premature Infants

MalaCards based summary : Sepsis in Premature Infants is related to secondary intestinal lymphangiectasia and acute hemorrhagic leukoencephalitis. An important gene associated with Sepsis in Premature Infants is CALCA (Calcitonin Related Polypeptide Alpha). The drugs Ceftriaxone and Budesonide have been mentioned in the context of this disorder. Affiliated tissues include testes.

Related Diseases for Sepsis in Premature Infants

Diseases related to Sepsis in Premature Infants via text searches within MalaCards or GeneCards Suite gene sharing:

id Related Disease Score Top Affiliating Genes
1 secondary intestinal lymphangiectasia 9.9 CALCA CRP
2 acute hemorrhagic leukoencephalitis 9.9 CALCA CRP
3 corneal ectasia 9.9 CALCA CRP
4 bazex syndrome 9.8 CALCA CRP
5 ceroid lipofuscinosis, neuronal, 8 9.8 CALCA CRP
6 primrose syndrome 9.8 CALCA CRP
7 epidermolysis bullosa dystrophica, ad 9.7 CALCA CRP

Graphical network of the top 20 diseases related to Sepsis in Premature Infants:



Diseases related to Sepsis in Premature Infants

Symptoms & Phenotypes for Sepsis in Premature Infants

Drugs & Therapeutics for Sepsis in Premature Infants

Drugs for Sepsis in Premature Infants (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 211)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ceftriaxone Approved Phase 4 73384-59-5 5479530 5361919
2
Budesonide Approved Phase 4,Phase 2 51333-22-3 63006 5281004
3 glucocorticoids Phase 4,Phase 3,Phase 2
4 Hormone Antagonists Phase 4,Phase 2,Phase 3,Phase 1
5 Hormones Phase 4,Phase 2,Phase 3,Phase 1
6 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 2,Phase 3,Phase 1
7 Anti-Asthmatic Agents Phase 4,Phase 3,Phase 2
8 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Phase 1
9 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
10 Anti-Inflammatory Agents Phase 4,Phase 2,Phase 3,Phase 1
11 Lactoferrin Phase 4,Phase 3,Phase 1,Phase 2,Early Phase 1
12 Respiratory System Agents Phase 4,Phase 3,Phase 2,Phase 1
13 penicillins Phase 4
14 Gentamicins Phase 4,Phase 2,Phase 3
15 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 3,Phase 1
16 Immunoglobulins Phase 4,Phase 2,Phase 3,Phase 1
17 Antibodies Phase 4,Phase 2,Phase 3,Phase 1
18 Autonomic Agents Phase 4,Phase 3,Phase 2,Phase 1
19 Bronchodilator Agents Phase 4,Phase 3,Phase 2
20 Pulmonary Surfactants Phase 4,Phase 2,Phase 3
21 Vaccines Phase 4
22
Nitrofurantoin Approved, Vet_approved Phase 3 67-20-9 5353830
23
Betamethasone Approved, Vet_approved Phase 3,Phase 2 378-44-9 9782
24
Pentoxifylline Approved, Investigational Phase 3,Phase 2 6493-05-6 4740
25
Clindamycin Approved, Vet_approved Phase 3 18323-44-9 29029
26
Nitric Oxide Approved Phase 3,Phase 2 10102-43-9 145068
27
Progesterone Approved, Vet_approved Phase 2, Phase 3 57-83-0 5994
28
Acetaminophen Approved Phase 3,Phase 1,Phase 2 103-90-2 1983
29
Ibuprofen Approved Phase 2, Phase 3, Phase 1 15687-27-1 3672
30
Meropenem Approved, Investigational Phase 3 119478-56-7 64778 441130
31
Benzocaine Approved Phase 2, Phase 3 1994-09-7, 94-09-7 2337
32
Metformin Approved Phase 3 657-24-9 14219 4091
33
Ampicillin Approved, Vet_approved Phase 2, Phase 3 69-53-4 6249
34
Mechlorethamine Approved Phase 3 51-75-2 4033
35
Sulbactam Approved Phase 2, Phase 3 68373-14-8
36 Beractant Approved Phase 2, Phase 3 108778-82-1
37
leucovorin Approved, Nutraceutical Phase 3 58-05-9 54575, 6560146 143
38 tannic acid Approved, Nutraceutical Phase 2, Phase 3
39
Cholecalciferol Approved, Nutraceutical Phase 2, Phase 3, Phase 1 67-97-0 6221 10883523 5280795
40
Ergocalciferol Approved, Nutraceutical Phase 2, Phase 3,Phase 1 50-14-6 5280793
41
Folic Acid Approved, Nutraceutical, Vet_approved Phase 3 59-30-3 6037
42 Betamethasone Valerate Phase 3,Phase 2 2152-44-5
43 Clindamycin palmitate Phase 3
44 Clindamycin phosphate Phase 3
45 Hematinics Phase 3,Phase 1,Phase 2
46 Vasodilator Agents Phase 3,Phase 2,Phase 1
47 Pharmaceutical Solutions Phase 3,Phase 2,Phase 1
48 Phosphodiesterase Inhibitors Phase 3,Phase 2
49 Platelet Aggregation Inhibitors Phase 3,Phase 2
50 Protective Agents Phase 3,Phase 2,Phase 1

Interventional clinical trials:

(show top 50) (show all 207)
id Name Status NCT ID Phase
1 Cpap at Delivery Room for Preterm Infants Unknown status NCT01024361 Phase 4
2 Early Versus Late Lactoferrin in Prevention of Neonatal Sepsis Completed NCT02959229 Phase 4
3 Infant Severe Sepsis and Bacterial Meningitis in Malawi Completed NCT01247909 Phase 4
4 Is a Woolen Cap Effective in Maintaining Normothermia in Preterm Infants During Kangaroo Mother Care? Completed NCT02645526 Phase 4
5 Evaluation of Use of Plastic Bags to Prevent Neonatal Hypothermia-Part V Completed NCT01604460 Phase 4
6 Evaluation of Use of Plastic Bags to Prevent Neonatal Hypothermia-Part IV Completed NCT01604447 Phase 4
7 Evaluation of Use of Plastic Bags to Prevent Neonatal Hypothermia-Part II Recruiting NCT01604421 Phase 4
8 Evaluation of Use of Plastic Bags to Prevent Neonatal Hypothermia-Part I Recruiting NCT01604317 Phase 4
9 Evaluation of Use of Plastic Bags to Prevent Neonatal Hypothermia-Part III Recruiting NCT01604434 Phase 4
10 Babies Born Early Antibody Response to Men B Vaccination: BEAR Men B Not yet recruiting NCT03125616 Phase 4
11 Cytokine Change in Bronchoalveolar Lavage Fluid After Early Budesonide-Surfactant Treatment in Premature Infants Terminated NCT00146497 Phase 4
12 Sodium Supplementation and Growth in Very Low Birth Weight Infants Terminated NCT01795638 Phase 4
13 Removal Versus Retention of Cerclage in Preterm Premature Rupture of Membranes (PPROM) Terminated NCT00201656 Phase 4
14 Randomized Study of Pessary Versus Standard Management in Women With Increased Chance of Premature Birth Unknown status NCT00735137 Phase 3
15 Cysteine Supplementation in Critically Ill Neonates Unknown status NCT00254176 Phase 2, Phase 3
16 Maternal Genitourinary Infections and Adverse Perinatal Outcomes Unknown status NCT01572532 Phase 3
17 Pentoxifylline and Late Onset Sepsis in Preterm Infants Completed NCT02163174 Phase 3
18 Glutamine Supplementation to Prevent Death or Infection in Extremely Premature Infants Completed NCT00005775 Phase 3
19 Lactoferrin for Prevention of Sepsis in Infants Completed NCT01525316 Phase 3
20 High-dose Ibuprofen for Patent Ductus Arteriosus (PDA) in Preterm Infant Completed NCT01243996 Phase 2, Phase 3
21 Bolus Versus Prolonged Infusion of Meropenem in Newborn With Late Onset Sepsis Completed NCT02503761 Phase 3
22 Donor Human Milk and Neurodevelopmental Outcomes in Very Low Birthweight (VLBW) Infants Completed NCT01232725 Phase 3
23 NIV Strategies for RDS in Preterm Infants. NIV (Non Invasive Ventilation), RDS (Respiratory Distress Syndrome) Completed NCT02259400 Phase 2, Phase 3
24 Vitamin D Supplementation for Extremely Preterm Infants Completed NCT01600430 Phase 2, Phase 3
25 Role of Probiotics for Prevention of NEC in Preterm VLBW Infants Completed NCT02650869 Phase 3
26 Intravenous Immune Globulin (IVIG) to Prevent Neonatal Infection Completed NCT01203345 Phase 2, Phase 3
27 17OHP for Reduction of Neonatal Morbidity Due to Preterm Birth (PTB) in Twin and Triplet Pregnancies Completed NCT00163020 Phase 2, Phase 3
28 Trial of Aggressive Versus Conservative Phototherapy in Infants <1,000 Grams Birth Weight Completed NCT00114543 Phase 3
29 Progesterone for Prevention of Preterm Birth in Women With Short Cervix: Randomized Controlled Trial Completed NCT00422526 Phase 3
30 Progesterone Vaginal Pessary for Prevention of Preterm Twin Birth Completed NCT02350231 Phase 2, Phase 3
31 Trial of Progesterone in Twins and Triplets to Prevent Preterm Birth (STTARS) Completed NCT00099164 Phase 3
32 PREGNANT Short Cervix Trial Completed NCT00615550 Phase 3
33 High Dose Folic Acid Supplementation Throughout Pregnancy for Preeclampsia Prevention Completed NCT01355159 Phase 3
34 Ibuprofen in Sepsis Study Completed NCT00000574 Phase 3
35 Prophylactic Acetaminophen for Prevention Intraventricular Hemorrhage in Premature Infants Recruiting NCT03024814 Phase 3
36 Maternal Omega-3 Supplementation to Reduce Bronchopulmonary Dysplasia Recruiting NCT02371460 Phase 3
37 Dose Reduction of Antenatal Betamethasone Given to Prevent the Neonatal Complications Associated With Very Preterm Birth Recruiting NCT02897076 Phase 3
38 Metformin in Women With Type 2 Diabetes in Pregnancy Trial Recruiting NCT01353391 Phase 3
39 Liberal Oxygenation Versus Conservative Oxygenation in ARDS Recruiting NCT02713451 Phase 3
40 Impact of Sunflower Seed Oil Massage on Neonatal Mortality and Morbidity in Nepal Active, not recruiting NCT01177111 Phase 3
41 Ampicillin / Sulbactam vs. Ampicillin / Gentamicin for Treatment of Chorioamnionitis Active, not recruiting NCT00879190 Phase 2, Phase 3
42 Darbepoetin Trial to Improve Red Cell Mass and Neuroprotection in Preterm Infants Not yet recruiting NCT03169881 Phase 3
43 Does a Rescue Course of Betamethasone in Pregnant Women With PPROM Decrease Neonatal Morbidity? Not yet recruiting NCT02939742 Phase 2, Phase 3
44 Efficacy and Safety of Goat Lung Surfactant for the Treatment of Respiratory Distress Syndrome in Preterm Neonates Not yet recruiting NCT02774044 Phase 2, Phase 3
45 Prophylactic Probiotics in Premature Infants Terminated NCT00727363 Phase 3
46 Probiotics for Prevention Neonatal Infection Terminated NCT01214473 Phase 2, Phase 3
47 Inhaled Nitric Oxide for Preterm Infants With Severe Respiratory Failure Terminated NCT00016523 Phase 3
48 Probiotics for the Prevention of Premature Birth and Neonatal Related Morbidity Terminated NCT00303082 Phase 3
49 Skin-to-skin Contact to Promote Bacterial Decolonization in Preterm Infants Unknown status NCT01498133 Phase 2
50 Recombinant Erythropoietin for Neuroprotection in Very Preterm Infants Unknown status NCT00910234 Phase 1, Phase 2

Search NIH Clinical Center for Sepsis in Premature Infants

Genetic Tests for Sepsis in Premature Infants

Anatomical Context for Sepsis in Premature Infants

MalaCards organs/tissues related to Sepsis in Premature Infants:

39
Testes

Publications for Sepsis in Premature Infants

Articles related to Sepsis in Premature Infants:

id Title Authors Year
1
Comparison of serum amyloid A concentrations with those of C-reactive protein and procalcitonin in diagnosis and follow-up of neonatal sepsis in premature infants. ( 19078972 )
2009
2
Is urine interleukin-8 level a reliable laboratory test for diagnosing late onset sepsis in premature infants? ( 17596292 )
2007

Variations for Sepsis in Premature Infants

Expression for Sepsis in Premature Infants

Search GEO for disease gene expression data for Sepsis in Premature Infants.

Pathways for Sepsis in Premature Infants

GO Terms for Sepsis in Premature Infants

Cellular components related to Sepsis in Premature Infants according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 8.62 CALCA CRP

Biological processes related to Sepsis in Premature Infants according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 8.62 CALCA CRP

Sources for Sepsis in Premature Infants

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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