MCID: SPT004
MIFTS: 60

Septic Arthritis malady

Categories: Rare diseases, Bone diseases

Aliases & Classifications for Septic Arthritis

Summaries for Septic Arthritis

MedlinePlus : 41 most kinds of arthritis cause pain and swelling in your joints. joints are places where two bones meet, such as your elbow or knee. infectious arthritis is an infection in the joint. the infection comes from a bacterial, viral, or fungal infection that spreads from another part of the body. symptoms of infectious arthritis include intense pain in the joint joint redness and swelling chills and fever inability to move the area with the infected joint one type of infectious arthritis is reactive arthritis. the reaction is to an infection somewhere else in your body. the joint is usually the knee, ankle, or toe. sometimes, reactive arthritis is set off by an infection in the bladder, or in the urethra, which carries urine out of the body. in women, an infection in the vagina can cause the reaction. for both men and women, it can start with bacteria passed on during sex. another form of reactive arthritis starts with eating food or handling something that has bacteria on it. to diagnose infectious arthritis, your health care provider may do tests of your blood, urine, and joint fluid. treatment includes medicines and sometimes surgery.

MalaCards based summary : Septic Arthritis, also known as infectious arthritis, is related to rheumatoid arthritis and neuropathy, and has symptoms including back pain, fever and muscle cramp. An important gene associated with Septic Arthritis is CRP (C-Reactive Protein), and among its related pathways/superpathways are Akt Signaling and Integrin Pathway. The drugs Cyclosporine and Tacrolimus have been mentioned in the context of this disorder. Affiliated tissues include testes, bone and skin, and related phenotypes are hematopoietic system and homeostasis/metabolism

NIH Rare Diseases : 50 infectious arthritis is joint pain, soreness, stiffness and swelling caused by a bacterial, viral, or fungal infection that spreads from another part of the body. depending on the type of infection, one or more joints may be affected. certain bacteria can cause a form of infectious arthritis called reactive arthritis, which appears to be caused by the immune system reacting to bacteria, rather than by the infection itself. in reactive arthritis, joint inflammation develops weeks, months or even years after the infection. reactive arthritis happens most commonly after infections of the genital and gastrointestinal tracts. to diagnose infectious arthritis, your health care provider may do tests of your blood, urine, and joint fluid. treatment includes medicines and sometimes surgery. last updated: 3/31/2012

Disease Ontology : 12 An arthritis that involves infection by a pathogen located in joint.

Wikipedia : 71 Septic arthritis, also known as infectious arthritis or joint infection, is the purulent invasion of a... more...

Related Diseases for Septic Arthritis

Diseases related to Septic Arthritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 179)
id Related Disease Score Top Affiliating Genes
1 rheumatoid arthritis 30.0 CRP CXCL8 MMP3 TLR2 TLR4
2 neuropathy 29.8 CRP CXCL8 TLR4
3 osteonecrosis 29.7 CRP CXCL8 MMP3
4 arthritis 10.9
5 osteomyelitis 10.3
6 pseudoainhum 10.3 TLR2 TLR4
7 myeloid proliferations related to down syndrome 10.2 CXCL8 TLR2
8 spotted fever 10.2 TLR2 TLR4
9 hypertensive heart disease 10.2 CRP TLR2 TLR4
10 myoclonic astatic epilepsy 10.2 CXCL8 TLR2
11 hyperlucent lung 10.2 CRP TLR2 TLR4
12 pericholangitis 10.2 CRP TLR2 TLR4
13 glycogen storage disease due to glucose-6-phosphatase deficiency 10.2 CCR3 CXCR3
14 omphalocele 10.2 CRP TLR4
15 sosby syndrome 10.2 CRP CXCL8
16 coronary arterial fistulas 10.2 CXCL8 TLR4
17 capillary leak syndrome 10.2 CRP CXCL8
18 neonatal hypoxic and ischemic brain injury 10.2 CXCL8 MMP2
19 ectothrix infectious disease 10.1 CXCL8 TLR2 TLR4
20 ovarian cystic teratoma 10.1 CXCL8 TLR2 TLR4
21 atrophy of prostate 10.1 CRP CXCL8 TLR2
22 myiasis 10.1 CRP CXCL8 TLR4
23 blepharochalasis 10.1 CRP CXCL8 TLR4
24 optic nerve hypoplasia 10.1 CXCL8 TLR2 TLR4
25 choroiditis 10.1 CRP CXCL8 TLR4
26 nephropathy with pretibial epidermolysis bullosa and deafness 10.1 CXCL8 TLR2 TLR4
27 asbestosis 10.1 CRP CXCL8 TLR2
28 infancy electroclinical syndrome 10.1 CRP CXCL8 TLR4
29 cardiomyopathy diabetes deafness 10.1 CRP CXCL8
30 crohn's colitis 10.1 CCR3 TLR2 TLR4
31 sclerosing adenosis of breast 10.1 CRP CXCL8 TLR2
32 neovascular glaucoma 10.1 CRP CXCL8 TLR4
33 benign eccrine breast spiradenoma 10.1 CXCL8 CXCR3 TLR4
34 primary optic atrophy 10.1 TLR2 TLR4
35 detrusor sphincter dyssynergia 10.1 CXCL8 TLR2 TLR4
36 bare lymphocyte syndrome, type i 10.1 CRP CXCL8 TLR4
37 uterine ligament clear cell adenocarcinoma 10.1 CRP CXCL8 TLR4
38 chordoid meningioma 10.1 CRP CXCL8 MMP3
39 stomach carcinoma in situ 10.1 CXCL8 DEFB4A TLR2
40 pulmonary eosinophilia 10.1 CRP CXCL8 TLR2
41 prostate embryonal rhabdomyosarcoma 10.1 CRP CXCR3 ITGA2
42 acute chest syndrome 10.1 CRP CXCL8 TLR4
43 synovium cancer 10.1 CRP CXCL8 MMP3
44 angiomyoma 10.1 MMP2 MMP3
45 handl syndrome 10.1 CXCL8 TLR2
46 bone angioendothelial sarcoma 10.1 CRP CXCL8 MMP3
47 childhood malignant hemangiopericytoma 10.1 CRP CXCL8 TLR4
48 pyomyositis 10.1
49 retinal artery occlusion 10.1 CCR3 MMP2 MMP3
50 wagr syndrome 10.1 CRP CXCL8 TLR4

Comorbidity relations with Septic Arthritis via Phenotypic Disease Network (PDN):


Acute Cystitis

Graphical network of the top 20 diseases related to Septic Arthritis:



Diseases related to Septic Arthritis

Symptoms & Phenotypes for Septic Arthritis

UMLS symptoms related to Septic Arthritis:


back pain, fever, muscle cramp, pruritus, sciatica

MGI Mouse Phenotypes related to Septic Arthritis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.97 RELA TLR2 TLR4 CCR3 CXCR3 ITGA2
2 homeostasis/metabolism MP:0005376 9.96 CCR3 CRP CXCR3 ITGA2 MMP2 MMP3
3 cardiovascular system MP:0005385 9.91 CRP CXCR3 MMP2 MMP7 RELA TLR2
4 immune system MP:0005387 9.81 CCR3 CRP CXCR3 MMP2 MMP3 MMP7
5 neoplasm MP:0002006 9.35 MMP2 MMP7 TLR2 TLR4 CXCR3
6 respiratory system MP:0005388 9.1 CCR3 CXCR3 MMP2 RELA TLR2 TLR4

Drugs & Therapeutics for Septic Arthritis

Drugs for Septic Arthritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 380)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cyclosporine Approved, Investigational, Vet_approved Phase 4 79217-60-0, 59865-13-3 5284373 6435893
2
Tacrolimus Approved, Investigational Phase 4,Phase 2 104987-11-3 445643 439492
3
Methotrexate Approved Phase 4,Phase 3,Phase 2,Phase 1 1959-05-2, 59-05-2 126941
4
Cyclophosphamide Approved, Investigational Phase 4,Phase 2,Phase 1 50-18-0, 6055-19-2 2907
5
Mycophenolic acid Approved Phase 4 24280-93-1 446541
6
Mycophenolate mofetil Approved, Investigational Phase 4 128794-94-5 5281078
7
Sulfasalazine Approved Phase 4,Phase 2,Phase 3,Phase 1 599-79-1 5353980 5359476
8
Hyaluronic acid Approved, Vet_approved Phase 4 9004-61-9 53477741 24759
9
Adalimumab Approved Phase 4,Phase 2,Phase 3 331731-18-1 16219006
10
Etanercept Approved, Investigational Phase 4,Phase 3,Phase 2 185243-69-0
11
Infliximab Approved Phase 4,Phase 3,Phase 2,Phase 1 170277-31-3
12
Hydroxychloroquine Approved Phase 4,Phase 3,Phase 2,Phase 1 118-42-3 3652
13
Prednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 50-24-8 5755
14
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 1,Phase 2 22916-47-8 4189
15
Calcium carbonate Approved Phase 4 471-34-1
16
Azithromycin Approved Phase 4,Phase 3 83905-01-5 55185 53477736 447043
17
Everolimus Approved Phase 4,Phase 1,Phase 2 159351-69-6 6442177
18
Vancomycin Approved Phase 4,Phase 2 1404-90-6 441141 14969
19
Linezolid Approved, Investigational Phase 4,Phase 2 165800-03-3 441401
20
Certolizumab pegol Approved Phase 4,Phase 3,Phase 1 428863-50-7
21
Methylprednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 83-43-2 6741
22
Sirolimus Approved, Investigational Phase 4,Phase 1,Phase 2 53123-88-9 5284616 6436030 46835353
23
Prednisone Approved, Vet_approved Phase 4,Phase 2 53-03-2 5865
24
Polidocanol Approved Phase 4 9002-92-0
25
Heparin Approved, Investigational Phase 4 9005-49-6 772 46507594
26
Colchicine Approved Phase 4,Phase 2 64-86-8 6167 2833
27
Indomethacin Approved, Investigational Phase 4,Phase 3 53-86-1 3715
28
Diclofenac Approved, Vet_approved Phase 4,Phase 3 15307-86-5 3033
29
Morphine Approved, Investigational Phase 4,Phase 2,Phase 3 57-27-2 5288826
30
Acetaminophen Approved Phase 4 103-90-2 1983
31
Celecoxib Approved, Investigational Phase 4,Phase 3,Phase 2 169590-42-5 2662
32
Alendronate Approved Phase 4 121268-17-5, 66376-36-1 2088
33
Azathioprine Approved Phase 4,Phase 3 446-86-6 2265
34
Allopurinol Approved Phase 4 315-30-0 2094
35
Naproxen Approved, Vet_approved Phase 4,Phase 3 22204-53-1 1302 156391
36
Tranexamic Acid Approved Phase 4 1197-18-8 5526
37
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
38
Chlorhexidine Approved, Vet_approved Phase 4,Phase 3,Phase 2 55-56-1 9552079 2713
39
Aceclofenac Approved Phase 4 89796-99-6
40
Dalteparin Approved Phase 4 9041-08-1
41
Tofacitinib Approved, Investigational Phase 4,Phase 3,Phase 2 477600-75-2
42
Triclosan Approved Phase 4 3380-34-5 5564
43
Dexamethasone Approved, Investigational, Vet_approved Phase 4 50-02-2 5743
44
Ketorolac Approved Phase 4,Phase 3 74103-06-3, 66635-83-4 3826
45
Hydrocodone Approved, Illicit Phase 4 125-29-1 5284569
46
Oxycodone Approved, Illicit, Investigational Phase 4,Phase 3 76-42-6 5284603
47
Hydromorphone Approved, Illicit Phase 4,Phase 3 466-99-9 5284570
48
Entecavir Approved, Investigational Phase 4,Phase 3 142217-69-4 153941
49
Ropivacaine Approved Phase 4,Phase 3 84057-95-4 71273 175805
50
Thioguanine Approved Phase 4 154-42-7 2723601

Interventional clinical trials:

(show top 50) (show all 622)
id Name Status NCT ID Phase
1 The Effect of Intraaricular Knee Injections of Hyaluronic Acid (HA) on Bone and Cartilaginous Debris, as a Therapeutic Indicator Unknown status NCT00422643 Phase 4
2 Oral Versus Intravenous Antibiotics for Bone and Joint Infections (OVIVA B&J) Unknown status NCT00974493 Phase 4
3 Vaccination Against Pertussis, Tetanus and Diphtheria in Patients Suffering From Rheumatoid Arthritis Unknown status NCT01301703 Phase 4
4 Effect of Tocilizumab to the Cellular Immune Response to Influenza Vaccine Unknown status NCT01980836 Phase 4
5 The Efficacy of Prednisone and Azithromycin in the Treatment of Patients With Cat Scratch Disease Unknown status NCT01469702 Phase 4
6 Safety and Efficacy of Anti-Pandemic H1N1 Vaccination in Rheumatic Diseases Unknown status NCT01151644 Phase 4
7 Immune Response After Human Papillomavirus Vaccination in Patients With Autoimmune Disease Unknown status NCT00815282 Phase 4
8 Everolimus + Very Low Tacrolimus vs Enteric-coated Mycophenolate Sodium + Low Tacrolimus in de Novo Renal Transplant Unknown status NCT02084446 Phase 4
9 An Assessment of Intra-lesional 3% Polidocanol Solution in the Treatment of Digital Myxoid Cyst Unknown status NCT02154789 Phase 4
10 Heart Function in Rheumatoid Arthritis and Ankylosing Spondylitis Pre and Post-TNF Blocker Unknown status NCT01072058 Phase 4
11 Cell Immunity Response to Vaccination Against Influenza in Patients With Rheumatoid Arthritis Unknown status NCT01002716 Phase 4
12 Effects of Biological Treatment on Blood Pressure and Endothelial Function in Patients With Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis Unknown status NCT02132234 Phase 4
13 Investigation of Sacroiliac Fusion Treatment (INSITE) Unknown status NCT01681004 Phase 4
14 Sensitivity and Specificity of QuantiFeron -TB Gold Test (QFT-G)in Patients With Psoriasis Unknown status NCT01223976 Phase 4
15 Bipolar Sealer Aquamantys Use in Total Knee Replacement Unknown status NCT01736644 Phase 4
16 Cyclosporine A in the TReatment of Interstitial Pneumonitis Associated With Sjogren's Syndrome Unknown status NCT02370550 Phase 4
17 Post-Operative Colonization Rates of Femoral Nerve Catheters Treated With Chlorhexidine-Impregnated Patch Completed NCT01411891 Phase 4
18 Study of Enbrel in Rheumatoid Arthritis (RA) Subjects With Comorbid Disorders Completed NCT00132418 Phase 4
19 Anti-TNF Agents for the Treatment of Rheumatoid Arthritis Completed NCT00837434 Phase 4
20 Compare Antimicrobial to Conventional Suture in Patients Receiving Primary Total Knee Replacement Completed NCT02533492 Phase 4
21 An Observational Study of Lymphoma in Patients With Rheumatoid Arthritis or Crohn's Disease. Completed NCT00440817 Phase 4
22 Duration of Immune Response to Influenza Vaccination in Patients With RA Completed NCT02311855 Phase 4
23 Study Evaluating the Efficacy of Enbrel (Etanercept) in Subjects in Japan Completed NCT00503503 Phase 4
24 A Long-term Safety Study of Infliximab (Remicade) Completed NCT00261976 Phase 4
25 A Study of Infliximab for Treatment Resistant Major Depression Completed NCT00463580 Phase 4
26 A Study To Evaluate The Effects Of Celecoxib (Celebrex®) Or Naproxen On Blood Pressure In Pediatric Subjects Completed NCT00807846 Phase 4
27 Preoperative Versus Postoperative Start With Thromboprophylaxis in THA (Total Hip Arthroplasty) Completed NCT01714297 Phase 4
28 Safety and Efficacy of Measles, Mumps, Rubella Vaccination in Juvenile Idiopathic Arthritis Completed NCT00731965 Phase 4
29 An Observational Study of Infliximab Injection in Ankylosing Spondylitis, Rheumatoid Arthritis, Psoriatic Arthritis and Psoriasis Participants Completed NCT00760669 Phase 4
30 Assessing the Use of Certolizumab Pegol in Adult Subjects With Rheumatoid Arthritis on the Antibody Response When Receiving Influenza Virus and Pneumococcal Vaccines Completed NCT00993668 Phase 4
31 Zurich Multiple Endpoint Vitamin D Trial in Knee OA Patients Completed NCT00599807 Phase 4
32 TNFalfa Blocking Treatment of Spondylarthropathies Completed NCT00133315 Phase 4
33 Tramadol/Acetaminophen(Ultracet) AS add-on Therapy in the Treatment of Patients With Ankylosing Spondylitis Completed NCT00647517 Phase 4
34 Intestinal Inflammation in Ankylosing Spondylitis and the Effects of Adalimumab on Mucosal Healing Completed NCT01174186 Phase 4
35 Initiation of Allopurinol at First Medical Contact for Acute Attacks of Gout Completed NCT01310673 Phase 4
36 Relapse of Ankylosing Spondylitis Patients Withdrawal Etanercept After Clinical Remission: a Following-up Study Completed NCT02915354 Phase 4
37 The Comparison of the Efficacy of Once and Twice Daily Colchicine Dosage in Pediatric Patients With FMF Completed NCT02602028 Phase 4
38 Efficacy and Safety of FLOSEAL for Hemostasis in Total Knee Arthroplasty Completed NCT01410240 Phase 4
39 Study Evaluating The Use Of Etanercept In Patients With Ankylosing Spondylitis Completed NCT00544557 Phase 4
40 A Study Of Celecoxib Versus Diclofenac In Patients With Ankylosing Spondylitis Completed NCT02528201 Phase 4
41 Effect of the Combination of Methotrexate and Adalimumab on Reduction of Immunization in Ankylosing Spondylitis (COMARIS) Completed NCT01895764 Phase 4
42 The Incidence of Extra-Articular Manifestations in Participants With Ankylosing Spondylitis Treated With Golimumab (MK-8259-012) Completed NCT01668004 Phase 4
43 Total Glucosides Paeony Capsules in Maintaining Clinical Remission in Patients With Ankylosing Spondylitis Which Achieve Clinical Remission After Anti-TNF Therapy Completed NCT01517620 Phase 4
44 Work Productivity in Active Ankylosing Spondylitis (AS) Patients Treated With Enbrel. Completed NCT01421303 Phase 4
45 Effect of Anti-TNF (Alpha) Treatment on Vascular Stiffness in Ankylosing Spondylitis (AS) Completed NCT01212653 Phase 4
46 Efficacy and Safety of Kunxian Capsule in Treatment Patients With Early Ankylosing Spondylitis Completed NCT00953979 Phase 4
47 Efficacy and Safety Study of Infliximab (Remicade) to Treat Early Ankylosing Spondylitis Completed NCT00936143 Phase 4
48 Study Evaluating Etanercept in Subjects With Ankylosing Spondylitis in Spain Completed NCT00873730 Phase 4
49 Growth Factor Concentration to Predict an Ankylosing Spondylitis Patient's Response to Infliximab (Study P04041)(COMPLETED) Completed NCT00779935 Phase 4
50 A Study of the Efficacy and Tolerance of Remicade in the Treatment of Active Ankylosing Spondylitis (Study P04042)(COMPLETED) Completed NCT00779012 Phase 4

Search NIH Clinical Center for Septic Arthritis

Cochrane evidence based reviews: arthritis, infectious

Genetic Tests for Septic Arthritis

Anatomical Context for Septic Arthritis

MalaCards organs/tissues related to Septic Arthritis:

39
Testes, Bone, Skin, Myeloid, Liver, Colon, Cervix

The Foundational Model of Anatomy Ontology organs/tissues related to Septic Arthritis:

18
Joint

Publications for Septic Arthritis

Articles related to Septic Arthritis:

(show top 50) (show all 701)
id Title Authors Year
1
Predicting Periarticular Infection in Children With Septic Arthritis of the Hip: Regionally Derived Criteria May Not Apply to All Populations. ( 28060181 )
2017
2
Mycobacterium avium Complex Septic Arthritis Presenting as Osteonecrosis of the Femoral Head in a Patient With Systemic Lupus Erythematosus. ( 28056158 )
2017
3
Arthrodesis for septic arthritis of the ankle: risk factors and complications. ( 27447881 )
2016
4
Pediatric hypervirulent Klebsiella pneumoniae septic arthritis. ( 27005513 )
2016
5
Adult Native Septic Arthritis in an Inner City Hospital: Effects on Length of Stay. ( 27111073 )
2016
6
Septic arthritis caused by Mycobacterium marinum infection. ( 27862193 )
2016
7
First diagnosis of septic arthritis in a dinosaur. ( 27853597 )
2016
8
Delayed treatment of septic arthritis in the neonate: A review of 52 cases. ( 28002339 )
2016
9
Life-threatening MRSA sepsis with bilateral pneumonia, osteomyelitis, and septic arthritis of the knee in a previously healthy 13-year-old boy: a case report. ( 27867536 )
2016
10
Septic Arthritis of an Atlantoaxial Facet Joint with Normal Inflammatory Markers: Case Report and Literature Review. ( 27993739 )
2016
11
Septic arthritis caused by Peptostreptococcus asaccharolyticus. ( 27155565 )
2016
12
Primary Bacterial Gluteal Pyomyositis: A Rare Disease in Temperate Climates Presenting as Suspected Septic Arthritis of the Hip. ( 27369856 )
2016
13
Rare case of Corynebacterium striatum septic arthritis. ( 27664229 )
2016
14
Mycotic Septic Arthritis of the Ankle Joint. ( 28005106 )
2016
15
Septic arthritis of the temporomandibular joint: a case report. ( 27595091 )
2016
16
Septic Arthritis Without a Clear Focus Due to Eikenella corrodens. ( 27567970 )
2016
17
When in Doubt, Examine the Patient: Commentary on an article by Keith D. Baldwin, MD, MSPT, MPH, et al.: "Predictive Factors for Differentiating Between Septic Arthritis and Lyme Disease of the Knee in Children". ( 27147695 )
2016
18
Septic arthritis of the knee due to Raoultella ornithinolytica. ( 27488819 )
2016
19
Septic arthritis in children in resource limited and non-resource limited countries: an update on diagnosis and treatment. ( 27629150 )
2016
20
Septic Arthritis of the Pediatric Shoulder: From Infancy to Adolescence. ( 27635147 )
2016
21
A population study of the reported incidence of native joint septic arthritis in the United Kingdom between 1998 and 2013. ( 27638811 )
2016
22
Key role of magnetic resonance imaging in the diagnosis of infections around the hip and pelvic girdle mimicking septic arthritis of the hip in children. ( 27007545 )
2016
23
Two-stage protocol and spacer implantation in the treatment of destructive septic arthritis of the hip joint. ( 27098293 )
2016
24
Laboratory predictors for risk of revision surgery in pediatric septic arthritis. ( 27174186 )
2016
25
Draft Whole-Genome Sequence of a Catalase-Negative Staphylococcus aureus subsp. aureus (Sequence Type 25) Strain Isolated from a Patient with Endocarditis and Septic Arthritis. ( 28007866 )
2016
26
Whipple destructive septic arthritis. ( 27860433 )
2016
27
The Contemporary Microbiology and Rates of Concomitant Osteomyelitis in Acute Septic Arthritis. ( 27870814 )
2016
28
Coexistent Pseudogout and Mycobacterium avium-intracellulare Septic Arthritis in a Patient with HIV and ESRD. ( 27803833 )
2016
29
Prognostic Factors Affecting the Clinical Outcome of Septic Arthritis of the Shoulder. ( 27595951 )
2016
30
A Medial Portal for Hip Arthroscopy in Children With Septic Arthritis: A Safety Study. ( 27603192 )
2016
31
Streptococcus bovis septic arthritis and osteomyelitis: A report of 21 cases and a literature review. ( 26992635 )
2016
32
Neutralization of MMP-2 protects Staphylococcus aureus infection induced septic arthritis in mice and regulates the levels of cytokines. ( 27554276 )
2016
33
A Neonatal Septic Arthritis Case Caused by Klebsiella pneumoniae: A Case Report. ( 27042550 )
2016
34
Surgical Management of Septic Arthritis. ( 27618571 )
2016
35
Septic arthritis due to Legionella cincinnatiensis: case report and review of the literature. ( 27848164 )
2016
36
Predictive Factors for Differentiating Between Septic Arthritis and Lyme Disease of the Knee in Children. ( 27147684 )
2016
37
Neonatal septic arthritis in a tertiary care hospital: a descriptive study. ( 27154290 )
2016
38
RAGE Deficiency Impairs Bacterial Clearance in Murine Staphylococcal Sepsis, but Has No Significant Impact on Staphylococcal Septic Arthritis. ( 27907047 )
2016
39
The use of continuous negative pressure after open debridement for septic arthritis of the shoulder. ( 27143738 )
2016
40
Staphylococcus capitis chronic non-destructive septic arthritis without orthopedic implant. ( 27132206 )
2016
41
Staphylococcus lugdunensis Septic Arthritis of a Native Knee A Case Report. ( 27815957 )
2016
42
Bilateral, simultaneous pneumococcal septic arthritis of the knees: a normal immune system, an unknown source. ( 27151056 )
2016
43
Septic arthritis of the knee: clinical and laboratory comparison of groups with different etiologies. ( 28076516 )
2016
44
An Unusual Case of Septic Arthritis of the Hip. ( 28050370 )
2016
45
Non-Type b Haemophilus influenzae Septic Arthritis in Children. ( 27150112 )
2016
46
Spontaneous septic arthritis due to Burkholderia cepacia in a 3-month-old pre-term infant. ( 27514974 )
2016
47
Risk assessment and usefulness of musculocutaneous flap transposition for recurrent septic arthritis of the hip in adults. ( 27132529 )
2016
48
Serum and Synovial Fluid Serum Amyloid A Response in Equine Models of Synovitis and Septic Arthritis. ( 27580707 )
2016
49
Brucella Septic Arthritis: Case Reports and Review of the Literature. ( 27200196 )
2016
50
Arthritis in children: comparison of clinical and biological characteristics of septic arthritis and juvenile idiopathic arthritis. ( 27655660 )
2016

Variations for Septic Arthritis

Expression for Septic Arthritis

Search GEO for disease gene expression data for Septic Arthritis.

Pathways for Septic Arthritis

Pathways related to Septic Arthritis according to GeneCards Suite gene sharing:

(show all 42)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.27 CCR3 CXCL8 CXCR3 ITGA2 TLR2 TLR4
2
Show member pathways
13.18 CCR3 CXCL8 CXCR3 ITGA2 MMP2 MMP3
3
Show member pathways
12.67 CXCL8 RELA TLR2 TLR4
4
Show member pathways
12.62 ITGA2 MMP2 MMP3 MMP7
5 12.55 CXCL8 ITGA2 MMP2 RELA
6 12.46 ITGA2 RELA TLR2 TLR4
7
Show member pathways
12.15 CXCL8 RELA TLR4
8
Show member pathways
12.14 RELA TLR2 TLR4
9 12.13 ITGA2 MMP2 TLR2 TLR4
10 12.12 CXCL8 MMP3 RELA
11 12.11 RELA TLR2 TLR4
12
Show member pathways
12.09 CXCL8 RELA TLR2 TLR4
13
Show member pathways
12.05 CXCL8 DEFB4A MMP3 RELA TLR2
14 12.02 ITGA2 TLR2 TLR4
15 11.98 MMP2 MMP7 TLR2 TLR4
16
Show member pathways
11.92 RELA TLR2 TLR4
17
Show member pathways
11.9 CCR3 CXCL8 CXCR3
18 11.87 CXCL8 MMP2 MMP3
19 11.79 CXCL8 MMP2 RELA
20
Show member pathways
11.79 MMP2 MMP3 MMP7
21 11.77 CXCL8 RELA TLR4
22 11.75 CXCL8 RELA TLR4
23
Show member pathways
11.74 CXCL8 RELA TLR4
24 11.71 MMP2 MMP3 MMP7
25 11.69 CXCL8 RELA TLR4
26 11.69 CXCL8 RELA TLR2 TLR4
27 11.68 ITGA2 TLR2 TLR4
28 11.62 CXCL8 RELA TLR4
29 11.62 CXCL8 MMP3 TLR2 TLR4
30 11.55 MMP2 MMP7 RELA
31 11.54 CXCL8 MMP2 RELA
32 11.51 CCR3 CXCL8 MMP2
33
Show member pathways
11.36 CXCL8 MMP2 MMP3 RELA
34 11.34 CXCL8 TLR2 TLR4
35 11.24 CXCL8 MMP2 MMP3 MMP7
36
Show member pathways
11.24 CXCL8 DEFB4A RELA TLR2 TLR4
37 11.13 CXCL8 ITGA2 MMP2
38 11.07 CCR3 TLR2
39 11.05 CXCL8 RELA
40 11 CXCL8 RELA TLR2 TLR4
41 10.98 RELA TLR2
42 10.93 CRP CXCL8

GO Terms for Septic Arthritis

Cellular components related to Septic Arthritis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.43 CRP CXCL8 DEFB4A MMP2 MMP3 MMP7
2 intrinsic component of plasma membrane GO:0031226 9.16 TLR2 TLR4
3 cell surface GO:0009986 9.02 CXCR3 ITGA2 MMP7 TLR2 TLR4

Biological processes related to Septic Arthritis according to GeneCards Suite gene sharing:

(show all 25)
id Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.92 CXCL8 DEFB4A TLR2 TLR4
2 response to hypoxia GO:0001666 9.79 ITGA2 MMP2 TLR2
3 defense response GO:0006952 9.75 CXCL8 DEFB4A RELA
4 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.74 RELA TLR2 TLR4
5 cellular response to lipopolysaccharide GO:0071222 9.72 CXCL8 RELA TLR4
6 extracellular matrix disassembly GO:0022617 9.63 MMP2 MMP3 MMP7
7 positive regulation of interferon-beta production GO:0032728 9.62 TLR2 TLR4
8 positive regulation of interleukin-8 production GO:0032757 9.61 TLR2 TLR4
9 cellular response to mechanical stimulus GO:0071260 9.61 ITGA2 MMP7 TLR4
10 positive regulation of interleukin-12 production GO:0032735 9.6 TLR2 TLR4
11 positive regulation of interleukin-10 production GO:0032733 9.59 TLR2 TLR4
12 positive regulation of NF-kappaB import into nucleus GO:0042346 9.58 TLR2 TLR4
13 chemokine-mediated signaling pathway GO:0070098 9.58 CCR3 CXCL8 CXCR3
14 positive regulation of chemokine production GO:0032722 9.56 TLR2 TLR4
15 positive regulation of nitric-oxide synthase biosynthetic process GO:0051770 9.54 TLR2 TLR4
16 defense response to Gram-positive bacterium GO:0050830 9.54 CRP DEFB4A TLR2
17 response to molecule of bacterial origin GO:0002237 9.52 CXCL8 TLR2
18 I-kappaB phosphorylation GO:0007252 9.51 TLR2 TLR4
19 collagen catabolic process GO:0030574 9.5 MMP2 MMP3 MMP7
20 regulation of cytokine secretion GO:0050707 9.49 TLR2 TLR4
21 cellular response to lipoteichoic acid GO:0071223 9.48 TLR2 TLR4
22 positive regulation of inflammatory response GO:0050729 9.33 ITGA2 TLR2 TLR4
23 positive regulation of interleukin-12 biosynthetic process GO:0045084 9.26 RELA TLR4
24 chemotaxis GO:0006935 9.26 CCR3 CXCL8 CXCR3 DEFB4A
25 inflammatory response GO:0006954 9.17 CCR3 CRP CXCL8 CXCR3 RELA TLR2

Molecular functions related to Septic Arthritis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 metallopeptidase activity GO:0008237 9.5 MMP2 MMP3 MMP7
2 lipopolysaccharide binding GO:0001530 9.26 TLR2 TLR4
3 chemokine receptor activity GO:0004950 9.16 CCR3 CXCR3
4 metalloendopeptidase activity GO:0004222 9.13 MMP2 MMP3 MMP7
5 lipopolysaccharide receptor activity GO:0001875 8.62 TLR2 TLR4

Sources for Septic Arthritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
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48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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