MCID: SRT002
MIFTS: 41

Sertoli Cell Tumor malady

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Summaries for Sertoli Cell Tumor

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Wikipedia:65 A Sertoli cell tumour, also Sertoli cell tumor (US spelling), is a Sex cord-gonadal stromal tumor of a... more...

MalaCards based summary: Sertoli Cell Tumor, also known as tubular androblastoma nos, is related to leydig cell tumor and seminoma. An important gene associated with Sertoli Cell Tumor is INHA (inhibin, alpha). The compounds ganglioside and nad+ have been mentioned in the context of this disorder. Affiliated tissues include testis, ovary and testes, and related mouse phenotype tumorigenesis.

Aliases & Classifications for Sertoli Cell Tumor

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Sources:
8Disease Ontology, 10DISEASES, 44Novoseek, 62UMLS, 57SNOMED-CT, 39NCIt, 34MeSH
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Sertoli Cell Tumor, Aliases & Descriptions:

Name: Sertoli Cell Tumor 8 10 44 62
 
Tubular Androblastoma Nos 8


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


External Ids:

Disease Ontology8 DOID:3577
NCIt39 C39976
MeSH34 D012707

Related Diseases for Sertoli Cell Tumor

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Diseases in the Sertoli Cell Tumor family:

Malignant Sertoli Cell Tumor

Diseases related to Sertoli Cell Tumor via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 93)
idRelated DiseaseScoreTop Affiliating Genes
1leydig cell tumor30.9INHA
2seminoma30.9INHA, AFP
3cushing's syndrome30.5INHA, SYP
4adenoma30.3MUC1, INHA, SYP
5neuroendocrine carcinoma30.3MUC1, SYP
6pheochromocytoma30.1SYP, INHA
7adenocarcinoma30.0SYP, MUC1, INHA, AFP
8malignant sertoli cell tumor10.8
9peutz-jeghers syndrome10.7
10gynecomastia10.5
11androgen insensitivity syndrome10.4
12cryptorchidism10.4
13gonadoblastoma10.4
14spermatic cord torsion10.3
15carney complex10.3
16prostatitis10.3
17fibrous meningioma10.3MUC1
18syringoma10.3MUC1
1921-hydroxylase deficiency10.2INHA, SYP
20endometrial stromal sarcoma10.2INHA, DES
21paraganglioma10.2SYP, DES
22adrenocortical carcinoma10.2SYP, INHA
23adrenal cortical adenoma10.2SYP, INHA
24germinoma10.2AFP, INHA
25endodermal sinus tumor10.2INHA, AFP
26dysgerminoma10.2INHA, AFP
27alopecia10.2
28frasier syndrome10.2
29hypertension10.2
30mast-cell sarcoma10.2
31familial adenomatous polyposis10.2
32arteriovenous malformation10.2
33prostatic cyst10.2
34brucellosis10.2
35gastric adenocarcinoma10.2
36hermaphroditism10.2
37hypothyroidism10.2
38peritonitis10.2
39prostate adenocarcinoma10.2
40renal adenoma10.2
41sarcoma10.2
42struma ovarii10.2
43thyroiditis10.2
44vaginitis10.2
45complete androgen insensitivity syndrome10.2
46precocious puberty10.2
47testicular cancer10.1AFP, INHA
48pituitary adenoma10.1SYP, INHA
49rhabdomyosarcoma10.1INHA, DES
50wilms tumor10.1DES, INHA

Graphical network of the top 20 diseases related to Sertoli Cell Tumor:



Diseases related to sertoli cell tumor

Symptoms for Sertoli Cell Tumor

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Drugs & Therapeutics for Sertoli Cell Tumor

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Drug clinical trials:

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Search NIH Clinical Center for Sertoli Cell Tumor

Genetic Tests for Sertoli Cell Tumor

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Anatomical Context for Sertoli Cell Tumor

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MalaCards organs/tissues related to Sertoli Cell Tumor:

32
Testis, Ovary, Testes, Bone, Bone marrow, Lung, Prostate, Thyroid

Animal Models for Sertoli Cell Tumor or affiliated genes

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MGI Mouse Phenotypes related to Sertoli Cell Tumor:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.6MUC1, AFP, INHA

Publications for Sertoli Cell Tumor

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Articles related to Sertoli Cell Tumor:

(show top 50)    (show all 172)
idTitleAuthorsYear
1
Observations on the paper "sclerosing Sertoli cell tumor of the testis: a clinicopathologic study of 20 cases" by Kao et al. (25025367)
2014
2
Struma ovarii simulating ovarian sertoli cell tumor: a case report with literature review. (23412916)
2013
3
Malignant large cell calcifying sertoli cell tumor of testis with skip metastasis to lung presented with peutz-jeghers syndrome. (25191441)
2012
4
Large cell calcifying Sertoli cell tumor: a clinicopathologic study of 1 malignant and 3 benign tumors using histomorphology, immunohistochemistry, ultrastructure, comparative genomic hybridization, and polymerase chain reaction analysis of the PRKAR1A gene. (20004940)
2010
5
Sertoli cell tumor, a rare testicular tumor, our experience and review of the literature. (20587845)
2010
6
Acute abdomen due to rupture of Sertoli cell tumor. (19597832)
2010
7
Case report of malignant sertoli cell tumor]. (18697473)
2008
8
Sertoli cell tumor of the testis: a case with late metastasis. (18500567)
2008
9
Benign large cell calcifying Sertoli cell tumor of the testis in a prepubescent patient. (17646440)
2007
10
Sertoli cell tumor of the testis, not otherwise specified, presenting extensive hemorrhage and overexpression of alpha-methylacyl-CoA racemase (AMACR/P504S). (17252229)
2007
11
Interstitial cell tumor and Sertoli cell tumor in the testis of a cat. (17491086)
2007
12
Testicular superoxide dismutase activity, heat shock protein 70 concentration and blood plasma inhibin-alpha concentration of dogs with a Sertoli cell tumor in a unilateral cryptorchid testis. (18176022)
2007
13
A 67-year-old woman with abdominal distention, vaginal bleeding, and elevated CA 125 level. Pure Sertoli cell tumor of the ovary with differentiation varying from well-differentiated tubules, to intermediate foci, to sarcomatoid spindle cell areas. (16683900)
2006
14
Large cell calcifying Sertoli cell tumor of the testis in a boy with brucellosis. (16970792)
2006
15
Carboplatin for treatment of a Sertoli cell tumor in a mallard (Anas platyrhynchos). (19754829)
2006
16
Sertoli cell tumor causing prepubertal gynecomastia in a boy with peutz-jeghers syndrome: the outcome of 1-year treatment with the aromatase inhibitor testolactone. (15947469)
2005
17
Sertoli cell tumor of the testis in children: reevaluation of a rarely encountered tumor. (16189443)
2005
18
Sclerosing Sertoli cell tumor of the testis. (16197877)
2005
19
Large cell calcifying Sertoli cell tumor of the testis: comparative immunohistochemical study with Leydig cell tumor. (15943795)
2005
20
Malignant seminoma with metastasis, Sertoli cell tumor, and pheochromocytoma in a spotted dolphin (Stenella frontalis) and malignant seminoma with metastasis in a bottlenose dolphin (Tursiops truncatus). (15872383)
2005
21
Sertoli cell tumors of the ovary: a clinicopathologic and immunohistochemical study of 54 cases. (15644771)
2005
22
Pathologic quiz case: testicular pain and scrotal swelling in a 25-year-old man. Large cell calcifying Sertoli cell tumor of the testis. (15387684)
2004
23
Simultaneous sertoli cell tumor and adenocarcinoma of the tunica vaginalis testis in a patient with testicular feminization. (11855889)
2002
24
A case report of Sertoli cell tumor in a patient with testicular feminization: many dilemmas for the pathologist. (19753733)
2002
25
Utility of immunostaining for S-100 protein subunits in gonadal sex cord-stromal tumors, with emphasis on the large-cell calcifying Sertoli cell tumor of the testis. (11979368)
2002
26
Sertoli cell proliferations of the infantile testis: an intratubular form of Sertoli cell tumor? (11688457)
2001
27
Pathological case of the month. Sertoli cell tumor. (10768686)
2000
28
Sclerosing sertoli cell tumor of the testis--a case report and review of the literature. (10452297)
1999
29
A case of large cell calcifying Sertoli cell tumor in a child with a history of nasal myxoid tumor in infancy. (10417694)
1999
30
Malignant large cell calcifying sertoli cell tumor with endocrine overactivity. (10210408)
1999
31
Malignant Sertoli cell tumor of the ovary metastatic to the lung mimicking neuroendocrine carcinoma: report of a case. (10459047)
1999
32
Metastatic testicular Sertoli-cell tumor: cytopathologic findings on fine-needle aspiration. (9702492)
1998
33
Sertoli cell tumor of the testis. Report of a case with imprint cytology findings. (9850662)
1998
34
Feminizing Sertoli cell tumors associated with Peutz-Jeghers syndrome: an increasingly recognized cause of prepubertal gynecomastia. (9734436)
1998
35
Sclerosing Sertoli cell tumor of the testis: a distinct histological subtype. (7563340)
1995
36
Carney's complex in a patient with hormone-producing Sertoli cell tumor of the testicle. (8411442)
1993
37
Fine needle aspiration cytology in malignant Sertoli cell tumor of the testis. A case report. (1636354)
1992
38
Large cell calcifying Sertoli cell tumor of the testis. A clinicopathologic, immunohistochemical, and ultrastructural study of two cases. (1746487)
1991
39
Fine needle aspiration cytology of a large cell calcifying Sertoli cell tumor of the testis. (3673461)
1987
40
Bone marrow hypoplasia in eight dogs with Sertoli cell tumor. (6113231)
1981
41
Malignant (androblastoma) Sertoli cell tumor of testes. (7281397)
1981
42
Gonadal stromal or sertoli cell tumor. (7052719)
1980
43
Peutz-Jeghers syndrome with feminizing sertoli cell tumor. (6770991)
1980
44
Sertoli cell tumor in two related newborn shorthorn calves. (7459797)
1980
45
Malignant androblastoma (Sertoli cell tumor) of the testis. A case report with a review of the literature. (167202)
1975
46
A sertoli-cell tumor in ectopic testicular tissue. (4747285)
1973
47
Malignant sertoli cell tumor of the testis. (5566364)
1971
48
Metastasizing Sertoli-cell tumor (androblastoma). (5812721)
1969
49
Androblastoma (Sertoli cell tumor): case report. (6057873)
1967
50
Sertoli cell tumor in an infant. (13346827)
1956

Variations for Sertoli Cell Tumor

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Expression for genes affiliated with Sertoli Cell Tumor

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Expression patterns in normal tissues for genes affiliated with Sertoli Cell Tumor

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Pathways for genes affiliated with Sertoli Cell Tumor

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Compounds for genes affiliated with Sertoli Cell Tumor

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Compounds related to Sertoli Cell Tumor according to GeneCards/GeneDecks:

(show top 50)    (show all 57)
idCompoundScoreTop Affiliating Genes
1ganglioside449.7SYP, DES
2nad+449.7DES, INHA
3ccl444 2810.7DES, AFP
4azathioprine44 2 50 1112.5AFP, DES
5lithium44 50 24 1112.4SYP, MUC1
6progestin449.4MUC1, DES
7polyethylene glycol449.3MUC1, AFP
8galactose449.3MUC1, AFP
9hydrogen44 2410.2INHA, AFP, SYP
10fatty acid449.2AFP, INHA, DES
11silver449.2SYP, AFP, DES
12mifepristone44 28 61 1112.2MUC1, AFP
13agarose449.2MUC1, INHA
14h2o2449.1SYP, AFP, DES
15biotin44 24 1111.1DES, INHA, MUC1
16acth449.1INHA, MUC1, SYP
17s 100449.1SYP, MUC1, DES
18forskolin44 50 1111.0SYP, MUC1, INHA
19reticulin449.0SYP, MUC1, DES
20mucicarmine449.0DES, MUC1, SYP
21sialic acid449.0MUC1, AFP
22formaldehyde44 2410.0SYP, MUC1, DES
23adriamycin448.9MUC1, AFP, DES
24actinomycin d448.9MUC1, AFP, DES
25thymidine44 249.9DES, AFP, MUC1
26cisplatin44 50 61 1111.8SYP, MUC1, AFP
27dihydrotestosterone44 28 24 1111.8MUC1, DES
28cholesterol44 28 24 1111.8AFP, MUC1, SYP
29dexamethasone44 50 28 1111.8AFP, MUC1, SYP
30steroid448.7DES, INHA, AFP, SYP
31nitric oxide44 24 1110.7SYP, MUC1, DES
32hematoxylin448.6DES, INHA, MUC1, SYP
33threonine448.6DES, AFP, MUC1
34cyclic amp44 249.6DES, INHA, MUC1, SYP
35b 723448.4SYP, MUC1, AFP, DES
36gold448.4SYP, MUC1, AFP, DES
37ethanol44 50 24 1111.4SYP, MUC1, AFP, DES
38oxygen44 249.4DES, AFP, MUC1
39glycogen44 249.4DES, AFP, MUC1, SYP
40creatinine448.4DES, AFP, MUC1, SYP
41vegf448.4DES, AFP, MUC1, SYP
42retinoic acid44 249.4DES, AFP, MUC1, SYP
43serine448.3SYP, MUC1, AFP, DES
44calcium44 50 24 1111.3DES, AFP, MUC1, SYP
45estradiol44 24 1110.0DES, INHA, AFP, MUC1, SYP
46paraffin448.0DES, INHA, AFP, MUC1, SYP
47progesterone44 28 61 24 1112.0DES, INHA, AFP, MUC1, SYP
48testosterone44 61 24 1111.0DES, INHA, AFP, MUC1, SYP
49estrogen448.0DES, INHA, AFP, MUC1, SYP
50tyrosine447.9SYP, MUC1, AFP, INHA, DES

GO Terms for genes affiliated with Sertoli Cell Tumor

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Products for genes affiliated with Sertoli Cell Tumor

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  • Antibodies
  • Proteins
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Sources for Sertoli Cell Tumor

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet