MCID: SRT002
MIFTS: 41

Sertoli Cell Tumor malady

Cancer diseases category

Summaries for Sertoli Cell Tumor

About this section
Sources:
66Wikipedia, 34MalaCards
See all sources

Fully expand this MalaCard

Download this MalaCard
Wikipedia:66 A Sertoli cell tumour, also Sertoli cell tumor (US spelling), is a Sex cord-gonadal stromal tumor of a... more...

MalaCards: Sertoli Cell Tumor, also known as tubular androblastoma nos, is related to seminoma and adenoma. An important gene associated with Sertoli Cell Tumor is INHA (inhibin, alpha). The compounds ganglioside and nad+ have been mentioned in the context of this disorder. Affiliated tissues include testis, ovary and testes, and related mouse phenotype tumorigenesis.

Aliases & Classifications for Sertoli Cell Tumor

About this section
Sources:
9Disease Ontology, 11DISEASES, 46Novoseek, 63UMLS, 59SNOMED-CT, 41NCIt, 36MeSH
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


Aliases & Descriptions:

sertoli cell tumor 9 11 46 63
tubular androblastoma nos 9


External Ids:

Disease Ontology9 DOID:3577
NCIt41 C39976
MeSH36 D012707

Related Diseases for Sertoli Cell Tumor

About this section
Sources:
18GeneCards, 19GeneDecks
See all sources

Diseases in the Sertoli Cell Tumor family:

Malignant Sertoli Cell Tumor

Diseases related to Sertoli Cell Tumor via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 94)
idRelated DiseaseScoreTop Affiliating Genes
1seminoma30.8INHA, AFP
2adenoma30.5MUC1, INHA, SYP
3adenocarcinoma30.4SYP, MUC1, INHA, AFP
4leydig cell tumor30.4INHA
5cushing's syndrome30.3INHA, SYP
6neuroendocrine carcinoma30.2MUC1, SYP
7pheochromocytoma30.2SYP, INHA
8malignant sertoli cell tumor10.7
9peutz-jeghers syndrome10.7
10gynecomastia10.4
11androgen insensitivity syndrome10.4
12cryptorchidism10.4
13gonadoblastoma10.4
14spermatic cord torsion10.3
15carney complex10.3
16mast-cell sarcoma10.1
17arteriovenous malformation10.1
18familial adenomatous polyposis10.1
19frasier syndrome10.1
20alopecia10.1
21brucellosis10.1
22gastric adenocarcinoma10.1
23hermaphroditism10.1
24hypertension10.1
25hypothyroidism10.1
26peritonitis10.1
27prostate adenocarcinoma10.1
28prostatitis10.1
29renal adenoma10.1
30sarcoma10.1
31struma ovarii10.1
32thyroiditis10.1
33vaginitis10.1
34complete androgen insensitivity syndrome10.1
35precocious puberty10.1
36ovarian malignant sertoli-leydig cell tumor10.1
37fibrous meningioma10.1MUC1
38syringoma10.1MUC1
3921-hydroxylase deficiency10.1INHA, SYP
40endometrial stromal sarcoma10.1INHA, DES
41glomus tumor10.0SYP, DES
42adrenocortical carcinoma10.0SYP, INHA
43adrenal adenoma10.0SYP, INHA
44germinoma10.0AFP, INHA
45endodermal sinus tumor10.0INHA, AFP
46dysgerminoma10.0INHA, AFP
47testicular cancer10.0AFP, INHA
48pituitary adenoma10.0SYP, INHA
49rhabdomyosarcoma10.0INHA, DES
50wilms tumor10.0DES, INHA

Graphical network of the top 20 diseases related to Sertoli Cell Tumor:



Diseases related to sertoli cell tumor

Symptoms for Sertoli Cell Tumor

About this section

Drugs & Therapeutics for Sertoli Cell Tumor

About this section
Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 63UMLS, 42NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Sertoli Cell Tumor

Drug clinical trials:

Search ClinicalTrials for Sertoli Cell Tumor

Search NIH Clinical Center for Sertoli Cell Tumor

Search CenterWatch for Sertoli Cell Tumor

Genetic Tests for Sertoli Cell Tumor

About this section

Anatomical Context for Sertoli Cell Tumor

About this section
Sources:
34MalaCards
See all sources

MalaCards organs/tissues related to Sertoli Cell Tumor:

34
Testis, Ovary, Testes, Bone marrow, Bone, Lung, Thyroid, Prostate

Animal Models for Sertoli Cell Tumor or affiliated genes

About this section
Sources:
38MGI
See all sources

MGI Mouse Phenotypes related to Sertoli Cell Tumor:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.6MUC1, AFP, INHA

Publications for Sertoli Cell Tumor

About this section
Sources:
53PubMed
See all sources

Articles related to Sertoli Cell Tumor:

(show top 50)    (show all 163)
idTitleAuthorsYear
1
Struma ovarii simulating ovarian sertoli cell tumor: a case report with literature review. (23412916)
2013
2
Magnetic resonance imaging findings of sclerosing Sertoli cell tumor of the testis. (23329316)
2013
3
Sertoli cell tumor and gonadoblastoma in an untreated 29-year-old 46,XY phenotypic male with Frasier syndrome carrying a WT1 IVS9+4C>T mutation. (22908070)
2012
4
Large cell calcifying Sertoli cell tumor: a clinicopathologic study of 1 malignant and 3 benign tumors using histomorphology, immunohistochemistry, ultrastructure, comparative genomic hybridization, and polymerase chain reaction analysis of the PRKAR1A gene. (20004940)
2010
5
Sertoli cell tumor, a rare testicular tumor, our experience and review of the literature. (20587845)
2010
6
Acute abdomen due to rupture of Sertoli cell tumor. (19597832)
2010
7
Case report of malignant sertoli cell tumor]. (18697473)
2008
8
Sertoli cell tumor of the testis: a case with late metastasis. (18500567)
2008
9
Benign large cell calcifying Sertoli cell tumor of the testis in a prepubescent patient. (17646440)
2007
10
Sertoli cell tumor of the testis, not otherwise specified, presenting extensive hemorrhage and overexpression of alpha-methylacyl-CoA racemase (AMACR/P504S). (17252229)
2007
11
Interstitial cell tumor and Sertoli cell tumor in the testis of a cat. (17491086)
2007
12
Testicular superoxide dismutase activity, heat shock protein 70 concentration and blood plasma inhibin-alpha concentration of dogs with a Sertoli cell tumor in a unilateral cryptorchid testis. (18176022)
2007
13
A 67-year-old woman with abdominal distention, vaginal bleeding, and elevated CA 125 level. Pure Sertoli cell tumor of the ovary with differentiation varying from well-differentiated tubules, to intermediate foci, to sarcomatoid spindle cell areas. (16683900)
2006
14
Large cell calcifying Sertoli cell tumor of the testis in a boy with brucellosis. (16970792)
2006
15
Carboplatin for treatment of a Sertoli cell tumor in a mallard (Anas platyrhynchos). (19754829)
2006
16
Sertoli cell tumor causing prepubertal gynecomastia in a boy with peutz-jeghers syndrome: the outcome of 1-year treatment with the aromatase inhibitor testolactone. (15947469)
2005
17
Sertoli cell tumor of the testis in children: reevaluation of a rarely encountered tumor. (16189443)
2005
18
Sclerosing Sertoli cell tumor of the testis. (16197877)
2005
19
Large cell calcifying Sertoli cell tumor of the testis: comparative immunohistochemical study with Leydig cell tumor. (15943795)
2005
20
Malignant seminoma with metastasis, Sertoli cell tumor, and pheochromocytoma in a spotted dolphin (Stenella frontalis) and malignant seminoma with metastasis in a bottlenose dolphin (Tursiops truncatus). (15872383)
2005
21
Sertoli cell tumors of the ovary: a clinicopathologic and immunohistochemical study of 54 cases. (15644771)
2005
22
Simultaneous sertoli cell tumor and adenocarcinoma of the tunica vaginalis testis in a patient with testicular feminization. (11855889)
2002
23
A case report of Sertoli cell tumor in a patient with testicular feminization: many dilemmas for the pathologist. (19753733)
2002
24
Utility of immunostaining for S-100 protein subunits in gonadal sex cord-stromal tumors, with emphasis on the large-cell calcifying Sertoli cell tumor of the testis. (11979368)
2002
25
Sertoli cell proliferations of the infantile testis: an intratubular form of Sertoli cell tumor? (11688457)
2001
26
Pathological case of the month. Sertoli cell tumor. (10768686)
2000
27
Sclerosing sertoli cell tumor of the testis--a case report and review of the literature. (10452297)
1999
28
A case of large cell calcifying Sertoli cell tumor in a child with a history of nasal myxoid tumor in infancy. (10417694)
1999
29
Malignant large cell calcifying sertoli cell tumor with endocrine overactivity. (10210408)
1999
30
Malignant Sertoli cell tumor of the ovary metastatic to the lung mimicking neuroendocrine carcinoma: report of a case. (10459047)
1999
31
Metastatic testicular Sertoli-cell tumor: cytopathologic findings on fine-needle aspiration. (9702492)
1998
32
Sertoli cell tumor of the testis. Report of a case with imprint cytology findings. (9850662)
1998
33
Feminizing Sertoli cell tumors associated with Peutz-Jeghers syndrome: an increasingly recognized cause of prepubertal gynecomastia. (9734436)
1998
34
Sclerosing Sertoli cell tumor of the testis: a distinct histological subtype. (7563340)
1995
35
Carney's complex in a patient with hormone-producing Sertoli cell tumor of the testicle. (8411442)
1993
36
Fine needle aspiration cytology in malignant Sertoli cell tumor of the testis. A case report. (1636354)
1992
37
Large cell calcifying Sertoli cell tumor of the testis. A clinicopathologic, immunohistochemical, and ultrastructural study of two cases. (1746487)
1991
38
Fine needle aspiration cytology of a large cell calcifying Sertoli cell tumor of the testis. (3673461)
1987
39
Bone marrow hypoplasia in eight dogs with Sertoli cell tumor. (6113231)
1981
40
Malignant (androblastoma) Sertoli cell tumor of testes. (7281397)
1981
41
Gonadal stromal or sertoli cell tumor. (7052719)
1980
42
Peutz-Jeghers syndrome with feminizing sertoli cell tumor. (6770991)
1980
43
Sertoli cell tumor in two related newborn shorthorn calves. (7459797)
1980
44
Malignant androblastoma (Sertoli cell tumor) of the testis. A case report with a review of the literature. (167202)
1975
45
Sertoli cell tumor of testis in childhood. (4415735)
1974
46
A sertoli-cell tumor in ectopic testicular tissue. (4747285)
1973
47
Malignant sertoli cell tumor of the testis. (5566364)
1971
48
Metastasizing Sertoli-cell tumor (androblastoma). (5812721)
1969
49
Androblastoma (Sertoli cell tumor): case report. (6057873)
1967
50
Sertoli cell tumor in an infant. (13346827)
1956

Variations for Sertoli Cell Tumor

About this section

Expression for genes affiliated with Sertoli Cell Tumor

About this section
Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Sertoli Cell Tumor

Search GEO for disease gene expression data for Sertoli Cell Tumor.

Pathways for genes affiliated with Sertoli Cell Tumor

About this section

Compounds for genes affiliated with Sertoli Cell Tumor

About this section
Sources:
46Novoseek, 30IUPHAR, 3BitterDB, 52PharmGKB, 12DrugBank, 25HMDB, 62Tocris Bioscience
See all sources

Compounds related to Sertoli Cell Tumor according to GeneCards/GeneDecks:

(show top 50)    (show all 57)
idCompoundScoreTop Affiliating Genes
1ganglioside469.7DES, SYP
2nad+469.7INHA, DES
3ccl446 3010.7AFP, DES
4azathioprine46 3 52 1212.5DES, AFP
5lithium46 52 25 1212.4MUC1, SYP
6progestin469.4MUC1, DES
7polyethylene glycol469.3AFP, MUC1
8galactose469.3AFP, MUC1
9hydrogen46 2510.2INHA, AFP, SYP
10fatty acid469.2INHA, DES, AFP
11silver469.2DES, AFP, SYP
12mifepristone46 30 62 1212.2AFP, MUC1
13agarose469.2INHA, MUC1
14h2o2469.1AFP, SYP, DES
15biotin46 25 1211.1INHA, MUC1, DES
16acth469.1INHA, MUC1, SYP
17s 100469.1SYP, DES, MUC1
18forskolin46 52 1211.0INHA, MUC1, SYP
19reticulin469.0SYP, DES, MUC1
20mucicarmine469.0SYP, MUC1, DES
21sialic acid469.0MUC1, AFP
22formaldehyde46 2510.0MUC1, SYP, DES
23adriamycin468.9AFP, MUC1, DES
24actinomycin d468.9MUC1, DES, AFP
25thymidine46 259.9AFP, MUC1, DES
26cisplatin46 52 62 1211.8SYP, MUC1, AFP
27dihydrotestosterone46 30 25 1211.8MUC1, DES
28cholesterol46 30 25 1211.8MUC1, SYP, AFP
29dexamethasone46 52 30 1211.8AFP, MUC1, SYP
30steroid468.7SYP, AFP, INHA, DES
31nitric oxide46 25 1210.7SYP, MUC1, DES
32hematoxylin468.6SYP, DES, INHA, MUC1
33threonine468.6MUC1, DES, AFP
34cyclic amp46 259.6MUC1, SYP, DES, INHA
35b 723468.4DES, AFP, MUC1, SYP
36gold468.4MUC1, AFP, SYP, DES
37ethanol46 52 25 1211.4AFP, SYP, MUC1, DES
38oxygen46 259.4AFP, MUC1, DES
39glycogen46 259.4SYP, MUC1, AFP, DES
40creatinine468.4DES, AFP, MUC1, SYP
41vegf468.4MUC1, AFP, DES, SYP
42retinoic acid46 259.4AFP, DES, MUC1, SYP
43serine468.3DES, SYP, AFP, MUC1
44calcium46 52 25 1211.3AFP, MUC1, SYP, DES
45estradiol46 25 1210.0DES, INHA, AFP, MUC1, SYP
46paraffin468.0AFP, SYP, MUC1, INHA, DES
47progesterone46 30 62 25 1212.0MUC1, SYP, DES, AFP, INHA
48testosterone46 62 25 1211.0DES, INHA, MUC1, SYP, AFP
49estrogen468.0INHA, DES, SYP, MUC1, AFP
50tyrosine467.9AFP, INHA, SYP, DES, MUC1

GO Terms for genes affiliated with Sertoli Cell Tumor

About this section

Products for genes affiliated with Sertoli Cell Tumor

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Sertoli Cell Tumor

About this section
4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet