Aliases & Classifications for Sexual Disorder

Aliases & Descriptions for Sexual Disorder:

Name: Sexual Disorder 12 14
Sexual Dysfunction 69

Classifications:



External Ids:

Disease Ontology 12 DOID:0060043

Summaries for Sexual Disorder

Disease Ontology : 12 A disease of mental health that involves the impairment in normal sexual functioning.

MalaCards based summary : Sexual Disorder, also known as sexual dysfunction, is related to 7q11.23 duplication syndrome and proliferating trichilemmal cyst, and has symptoms including decreased libido and increased libido. An important gene associated with Sexual Disorder is PDE5A (Phosphodiesterase 5A), and among its related pathways/superpathways are Vascular smooth muscle contraction and Prolactin Signaling Pathway. The drugs Felodipine and Irbesartan have been mentioned in the context of this disorder. Affiliated tissues include prostate, and related phenotypes are cardiovascular system and nervous system

Wikipedia : 71 Sexual dysfunction (or sexual malfunction or sexual disorder) is difficulty experienced by an individual... more...

Related Diseases for Sexual Disorder

Diseases related to Sexual Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 43)
id Related Disease Score Top Affiliating Genes
1 7q11.23 duplication syndrome 10.3 NOS1 NOS3 PRL
2 proliferating trichilemmal cyst 10.2 EDN1 NOS3
3 gastroduodenal crohn's disease 10.2 ALDH7A1 NOS1 NOS3
4 glioblastoma mesenchymal subtype 10.2 KLK3 PRL SHBG
5 astroblastoma 10.2 OXT PRL SHBG
6 dry eye syndrome 10.2 HTR1A PDE5A SHBG
7 retroperitoneal sarcoma 10.2 NOS3 PRL SHBG
8 polyneuropathy 10.2 HTR1A SHBG
9 capillary disease 10.2 KLK3 PRL SHBG
10 traumatic glaucoma 10.2 EDN1 NOS3 PDE5A
11 spondylolysis 10.2 OXT PRL SHBG
12 renovascular hypertension 10.2 EDN1 NOS1 NOS3
13 kartagener syndrome 10.2 ACE NOS3 PDE5A
14 villous adenoma 10.2 ACE NOS3 PDE5A
15 exocervical carcinoma 10.1 KLK3 PDE5A PRL SHBG
16 avoidant personality disorder 10.1 KLK3 OXT PRL SHBG
17 necrobiosis lipoidica 10.1 KLK3 PRL SHBG
18 chronic conjunctivitis 10.1 HTR1A NOS1 OXT PRL
19 aplasia cutis congenita recessive 10.1 ACE EDN1 NOS3
20 lymphadenitis 10.1 ACE EDN1 NOS3
21 hypothyroidism, congenital nongoitrous, 5 10.1 ACE KCNMA1
22 acute posterior multifocal placoid pigment epitheliopathy 10.1 ACE EDN1 NOS3
23 oppositional defiant disorder 10.1 ACE EDN1 NOS3
24 rapidly progressive glomerulonephritis 10.1 ACE ALDH7A1 NOS3 PDE5A
25 hepatitis d 10.1 HTR1A OXT PRL
26 pyelonephritis 10.1 ACE EDN1 NOS3
27 body dysmorphic disorder 10.1 ACE NOS3 PRL SHBG
28 limb ischemia 10.1 ACE EDN1 NOS3
29 diabetic encephalopathy 10.1 ACE EDN1 NOS3
30 alpha-2-plasmin inhibitor deficiency 10.0 ACE EDN1 NOS3 PDE5A
31 testicular lymphoma 10.0 ACE EDN1 PRL
32 cone-rod dystrophy 3 10.0 ALDH7A1 KCNMA1
33 calcinosis 9.9 ACE EDN1 KLK3
34 xanthogranulomatous pyelonephritis 9.9 ACE EDN1 NOS3 PDE5A
35 sydenham chorea 9.8 ACE EDN1 NOS3 PDE5A RHOA
36 prostatic hypertrophy 9.5
37 social phobia 9.5
38 fetishism 9.5
39 gynecomastia 9.5
40 premature ejaculation 9.5
41 prostatitis 9.5
42 viral hepatitis 9.4 ACE ALDH7A1 EDN1 KCNMA1 KLK3 NOS1
43 aphasia 7.9 ACE ALDH7A1 EDN1 HTR1A KCNMA1 KLK3

Graphical network of the top 20 diseases related to Sexual Disorder:



Diseases related to Sexual Disorder

Symptoms & Phenotypes for Sexual Disorder

UMLS symptoms related to Sexual Disorder:


decreased libido, increased libido

MGI Mouse Phenotypes related to Sexual Disorder:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.91 ACE EDN1 HTR1A KCNMA1 NOS1 NOS3
2 nervous system MP:0003631 9.9 RHOA ROCK2 SEPT3 EDN1 HTR1A KCNMA1
3 normal MP:0002873 9.56 ALDH7A1 EDN1 NOS1 NOS3 PRKG1 RHOA
4 renal/urinary system MP:0005367 9.17 ACE EDN1 KCNMA1 NOS1 NOS3 OXT

Drugs & Therapeutics for Sexual Disorder

Drugs for Sexual Disorder (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 1205)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Felodipine Approved, Investigational Phase 4 72509-76-3 3333
2
Irbesartan Approved, Investigational Phase 4 138402-11-6 3749
3
Metoprolol Approved, Investigational Phase 4 37350-58-6, 51384-51-1 4171
4
Aripiprazole Approved, Investigational Phase 4,Phase 2 129722-12-9 60795
5
Dopamine Approved Phase 4,Phase 3,Phase 2,Phase 1 51-61-6, 62-31-7 681
6
Risperidone Approved, Investigational Phase 4,Phase 3,Phase 1 106266-06-2 5073
7
Methyltestosterone Approved Phase 4,Phase 3,Phase 1,Phase 2,Early Phase 1 58-18-4 6010
8
Testosterone Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2,Early Phase 1 58-22-0 6013
9
Nebivolol Approved, Investigational Phase 4 152520-56-4, 99200-09-6, 118457-14-0 71301
10
Tadalafil Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 171596-29-5 110635
11
Bupivacaine Approved, Investigational Phase 4,Phase 1 2180-92-9, 38396-39-3 2474
12
Triamcinolone Approved, Vet_approved Phase 4 124-94-7 31307
13
Benzocaine Approved Phase 4,Phase 3,Phase 2 1994-09-7, 94-09-7 2337
14
Drospirenone Approved Phase 4,Phase 3,Phase 2 67392-87-4 68873
15
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 50-28-2 5757 53477783
16
Ethinyl Estradiol Approved Phase 4,Phase 3,Phase 2,Phase 1 57-63-6 5991
17
Azithromycin Approved Phase 4,Phase 3,Phase 2,Phase 1 83905-01-5 55185 53477736 447043
18
Prednisone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 53-03-2 5865
19
Acetylcholine Approved Phase 4,Phase 3,Phase 2,Phase 1 51-84-3 187
20
Povidone-iodine Approved Phase 4 25655-41-8
21
Letrozole Approved, Investigational Phase 4,Phase 3,Phase 2 112809-51-5 3902
22
Acetylcysteine Approved, Investigational Phase 4,Phase 2,Phase 1 616-91-1 12035
23
Ezetimibe Approved Phase 4,Phase 2 163222-33-1 150311
24
Warfarin Approved Phase 4,Phase 2,Phase 3,Phase 1 81-81-2 6691 54678486
25
Emtricitabine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 143491-57-0 60877
26
Tenofovir Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 147127-20-6 464205
27
Copper Approved Phase 4,Phase 2,Phase 1 15158-11-9, 7440-50-8 27099
28
Norethindrone Approved Phase 4,Phase 3,Phase 2 68-22-4 6230
29
Abacavir Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 136470-78-5 65140 441300
30
Darunavir Approved Phase 4,Phase 2,Phase 3,Phase 1 635728-49-3, 206361-99-1 213039
31
Lamivudine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 134678-17-4 60825
32
Ritonavir Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 155213-67-5 392622
33
Mycophenolate mofetil Approved, Investigational Phase 4,Phase 2 128794-94-5 5281078
34
Mycophenolic acid Approved Phase 4,Phase 2 24280-93-1 446541
35
Efavirenz Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 154598-52-4 64139
36
Lopinavir Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 192725-17-0 92727
37
Zidovudine Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 30516-87-1 35370
38
Citalopram Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 59729-33-8 2771
39
Paroxetine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 61869-08-7 43815
40
Buprenorphine Approved, Illicit, Investigational, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 52485-79-7 40400 644073
41
Artemether Approved Phase 4,Phase 3 71963-77-4 119380 68911
42
Lumefantrine Approved Phase 4,Phase 3 82186-77-4 6437380
43
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 22916-47-8 4189
44
Nevirapine Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 129618-40-2 4463
45
Rifampin Approved Phase 4,Phase 3,Phase 2,Phase 1 13292-46-1 5458213 5381226
46
Guaifenesin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 93-14-1 3516
47
Methadone Approved Phase 4,Phase 3,Phase 1,Phase 2 76-99-3 4095
48
Isoniazid Approved Phase 4,Phase 3,Phase 2,Phase 1 54-85-3 3767
49
Cyclosporine Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 1 79217-60-0, 59865-13-3 5284373 6435893
50
Alfuzosin Approved, Investigational Phase 4,Phase 3 81403-80-7 2092

Interventional clinical trials:

(show top 50) (show all 5000)
id Name Status NCT ID Phase
1 Clinical Study to Assess the Influence of a Saw Palmetto Preparation in Patients With Benign Prostatic Hyperplasia (BPH) and Sexual Dysfunctions Unknown status NCT01021267 Phase 4
2 Combined Antihypertensive Therapy and Sexual Dysfunction Unknown status NCT01238705 Phase 4
3 A Multicenter Study to Evaluate the Effects of Switching to Aripiprazole 12 Weeks on the Sexual Dysfunction From Risperidone or Paliperidone in Patients With Schizophrenia Spectrum Disorders or Bipolar Spectrum Disorders Unknown status NCT01742390 Phase 4
4 Effect of Sildenafil on Quality of Sexual Life in Mild to Normally Sexually Functioning Males Unknown status NCT00313898 Phase 4
5 Functional Outcome After Groin Hernia Mesh Repair: Open Versus Laparoscopy Unknown status NCT00625534 Phase 4
6 Testosterone Patch's Effects on the Cardiovascular System and Libido Unknown status NCT01208038 Phase 4
7 Safety and Clinical Effectiveness of 2 Lower Dose Combined PDE5i's vs. Single Maximal Dose PDE5i Unknown status NCT00498680 Phase 4
8 Nebivolol Effects on Endothelial Function and Erectile Function Unknown status NCT01885988 Phase 4
9 Evaluation of Safety and Effectiveness of 2 Lower Dose Combined PDE5i's Versus Single Maximal Dose PDE5i Treatment Unknown status NCT01364701 Phase 4
10 Treatment of Erectile Dysfunction in Hypogonadal Men With Testosterone Undecanoate Unknown status NCT00555087 Phase 4
11 Trigger Point Injections and Pelvic Rehabilitation for the Treatment of Pelvic Floor Myalgia and Sexual Pain Unknown status NCT02022722 Phase 4
12 The Incidence and Treatment of Insulin Resistance Among Men With Erectile Dysfunction Unknown status NCT00284960 Phase 4
13 A Study to Evaluate the Efficacy and Safety of Vardenafil in Men With Erectile Dysfunction Caused by Spinal Cord Injury Unknown status NCT00725790 Phase 4
14 Continuous Versus Cyclic Oral Contraceptives for Endometriosis Unknown status NCT02237131 Phase 4
15 Can Hyperbaric Oxygen Improve Erectile Function Following Surgery for Prostate Cancer Unknown status NCT00906269 Phase 4
16 Weight Reduction Alone May Not be Sufficient to Maintain Disease Remission in Obese Patients With Psoriasis Unknown status NCT01439425 Phase 4
17 A Prospective, Placebo Controlled, Double-Blind, Cross-over Study on the Effects of a Probiotic Preparation (VSL#3) on Metabolic Profile, Intestinal Permeability, Microbiota, Cytokines and Chemokines Expression and Other Inflammatory Markers in Pediatric Unknown status NCT01632462 Phase 4
18 Female Sexual Function and Back Pain Unknown status NCT01420276 Phase 4
19 The Efficacy of Prednisone and Azithromycin in the Treatment of Patients With Cat Scratch Disease Unknown status NCT01469702 Phase 4
20 Botox on Vulvar Vestibulitis Unknown status NCT00119886 Phase 4
21 Immunogenicity of Influenza Vaccines in HIV-infected Persons in Thailand Unknown status NCT01538940 Phase 4
22 Primary and Secondary Prevention of Human Papillomavirus (HPV) Disease in China Unknown status NCT01021904 Phase 4
23 Sex Steroids in Sjögren's Syndrome: Effect of Substitution Treatment on Fatigue Unknown status NCT00543166 Phase 4
24 Efficacy and Safety of Pulsatile Gonadotropin Releasing Hormone Pump Treatment in Patients With Idiopathic Hypogonadotropic Hypogonadism Unknown status NCT02310074 Phase 4
25 Odense Androgen Study - The Effect of Testim and Training in Hypogonadal Men Unknown status NCT00700024 Phase 4
26 A Prospective Trial of Povidone-iodine Suppository Before Transrectal Ultrasound Guided Prostate Biopsy Unknown status NCT02245334 Phase 4
27 Evaluation of Predictive Factors Regarding the Effectivity of Aromatase Inhibitor Therapy (PreFace) Unknown status NCT01908556 Phase 4
28 Comparative Study of Mesh Versus No Mesh in Prolapse Surgery Unknown status NCT00153257 Phase 4
29 Anti-Oxidant Effect on Peritoneal Membrane in Peritoneal Dialysis (PD) Patients Unknown status NCT01111422 Phase 4
30 A Study Evaluating the Effects of Lipid Lowering Treatment on Steroid Synthesis Unknown status NCT00433823 Phase 4
31 Continuous Postoperative Use of Low-Dose Combined Oral Contraceptivesfor for Endometriosis-Related Chronic Pelvic Pain Unknown status NCT00844012 Phase 4
32 The Effect of N-Acetylcystein on Quality of Life and Air Trapping During Rest and After Exercise Unknown status NCT00476736 Phase 4
33 Effect of Rotigotine Patch Treatment on Cardiovascular Markers in Idiopathic Restless Legs Syndrome Unknown status NCT01823770 Phase 4
34 Applying Pharmacogenetics to Warfarin Dosing in Chinese Patients Unknown status NCT01610141 Phase 4
35 PrEP Demonstration Project (PRELUDE Study) Unknown status NCT02206555 Phase 4
36 Comparative Validation of the Triptorelin Test for the Diagnosis of CPP in Girls Unknown status NCT01278290 Phase 4
37 Oral Contraceptive Ethinyl Estradiol Dose Effect on Postpartum Depression and Sexual Functioning Scales Unknown status NCT02210702 Phase 4
38 Evaluation of the Efficacy and Safety Between Two Antiretroviral Regimens, in HIV-1-infected Treatment-naïve Subjects With Low CD4 Counts Unknown status NCT01928407 Phase 4
39 Effects of Mycophenolate Mofetil (MMF) on Surrogate Markers for Cardiovascular Disease in HIV-1 Infected Patients Unknown status NCT00247494 Phase 4
40 Pilot Study With Isentress (Raltegravir) and Epzicom (Abacavir/Lamivudine) in Treatment Naive HIV-Infected Subjects Unknown status NCT00740064 Phase 4
41 PI Vs. NNRTI Based Therapy for HIV Advanced Disease Unknown status NCT00162643 Phase 4
42 Clinical Pharmacogenomics of Antidepressant Response Unknown status NCT00269334 Phase 4
43 7-valent Pneumococcal Conjugated Vaccination Unknown status NCT00885625 Phase 4
44 Comparing a Nucleoside-Analogue-Sparing Regimen and a Protease-Inhibitor-Sparing Regimen in HIV Infected Patients Unknown status NCT00135460 Phase 4
45 Buprenorphine and Integrated HIV Care Evaluation Unknown status NCT00124358 Phase 4
46 Protease Inhibitor Monotherapy Versus Ongoing Triple-therapy in the Long Term Management of HIV Infection (PIVOT) Unknown status NCT01230580 Phase 4
47 Impaired Decision Making in Pedophilic Offenders Unknown status NCT01541150 Phase 4
48 Drug Interaction Between Coartem® and Nevirapine, Efavirenz or Rifampicin in HIV Positive Ugandan Patients Unknown status NCT00620438 Phase 4
49 Safety and Efficacy Study Comparing Raltegravir to a Protease Inhibitor in Treatment-naïve, HIV/Hepatitis C Drug Users Unknown status NCT01105611 Phase 4
50 Diagnosis and Treatment of Co-infection With Human Immunodeficiency Virus /Latent Tuberculosis Infection (HIV/TBL) Unknown status NCT01875952 Phase 4

Search NIH Clinical Center for Sexual Disorder

Genetic Tests for Sexual Disorder

Anatomical Context for Sexual Disorder

MalaCards organs/tissues related to Sexual Disorder:

39
Prostate

Publications for Sexual Disorder

Articles related to Sexual Disorder:

(show all 19)
id Title Authors Year
1
Technological change and sexual disorder. ( 27028747 )
2016
2
Hebephilia as a sexual disorder. ( 25723776 )
2015
3
Sexual disorder improvement: a target or a way in treatment of fibromyalgia. A case report and brief review. ( 19802653 )
2010
4
Drug treatment of paraphilic and nonparaphilic sexual disorders. ( 19243704 )
2009
5
Male sexuality and psychological trauma: soldiers and sexual disorder in World War I and Weimar Germany. ( 19260157 )
2008
6
Finasteride: new indication. Benign prostatic hypertrophy: sexual disorders. ( 17724838 )
2007
7
Treatment of paraphilic sexual disorder: the use of topiramate in fetishism. ( 16687996 )
2006
8
Comorbidity between social phobia and premature ejaculation: study on 242 males affected by sexual disorders. ( 16418108 )
2006
9
[The significance of the androgen-estrogen ratios in the clinical picture of sexual disorders in men]. ( 10878975 )
2000
10
Female hypoactive sexual disorder: case studies of physiologic androgen replacement. ( 10407790 )
1999
11
Pharmacological era in the treatment of sexual disorder. ( 9611685 )
1998
12
Gynecomastia and sexual disorders after the administration of omeprazole. ( 7771409 )
1995
13
Neurotransmitter, opiodergic system, steroid-hormone interaction and involvement in the replacement therapy of sexual disorders. ( 1979499 )
1990
14
Interruption in the maintenance of compulsive sexual disorder: two case studies. ( 3219064 )
1988
15
Treatment of sexual disorder: a prophylaxis for major pathology? ( 3820157 )
1987
16
Dyspareunia; a symptom of sexual disorder in the female. ( 1043847 )
1976
17
A note on avoidance conditioning techniques in sexual disorder. ( 5853245 )
1965
18
SEXUAL DISORDER IN POSTTRAUMATIC AND POSTCONCUSSIONAL STATES. ( 14128413 )
1964
19
Sexual disorder in 'mepacrine psychoses'. ( 15412077 )
1950

Variations for Sexual Disorder

Expression for Sexual Disorder

Search GEO for disease gene expression data for Sexual Disorder.

Pathways for Sexual Disorder

Pathways related to Sexual Disorder according to GeneCards Suite gene sharing:

(show all 15)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
12.46 KCNMA1 NOS3 OXT PDE5A PRKG1 RHOA
2
Show member pathways
12.28 NOS3 PRL RHOA ROCK2
3
Show member pathways
11.94 EDN1 PRKG1 RHOA ROCK2
4
Show member pathways
11.93 KCNMA1 NOS1 NOS3 PDE5A PRKG1
5 11.8 NOS1 RHOA ROCK2
6 11.79 NOS3 PRKG1 RHOA ROCK2
7 11.78 NOS3 RHOA ROCK2
8 11.65 KLK3 RHOA ROCK2
9 11.5 NOS1 RHOA ROCK2
10 11.5 RHOA SEPT3 SEPT6 SEPT8
11
Show member pathways
11.39 ALDH7A1 NOS1 NOS3
12 10.96 NOS3 RHOA ROCK2
13
Show member pathways
10.64 KCNMA1 NOS1 NOS3 PDE5A PRKG1
14 10.38 NOS1 NOS3
15 10.25 NOS1 NOS3 PDE5A

GO Terms for Sexual Disorder

Cellular components related to Sexual Disorder according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytoskeleton GO:0005856 9.5 NOS1 NOS3 RHOA ROCK2 SEPT3 SEPT6
2 caveola GO:0005901 8.8 KCNMA1 NOS1 NOS3

Biological processes related to Sexual Disorder according to GeneCards Suite gene sharing:

(show all 17)
id Name GO ID Score Top Affiliating Genes
1 regulation of blood pressure GO:0008217 9.58 ACE EDN1 NOS3
2 nitric oxide mediated signal transduction GO:0007263 9.57 NOS1 NOS3
3 vasoconstriction GO:0042310 9.56 EDN1 HTR1A
4 regulation of blood vessel size GO:0050880 9.55 EDN1 NOS3
5 positive regulation of cardiac muscle hypertrophy GO:0010613 9.54 EDN1 PDE5A
6 positive regulation of renal sodium excretion GO:0035815 9.52 EDN1 OXT
7 nitric oxide biosynthetic process GO:0006809 9.51 NOS1 NOS3
8 negative regulation of calcium ion transport GO:0051926 9.49 NOS1 NOS3
9 positive regulation of guanylate cyclase activity GO:0031284 9.48 NOS1 NOS3
10 negative regulation of potassium ion transport GO:0043267 9.46 NOS1 NOS3
11 response to hypoxia GO:0001666 9.46 EDN1 KCNMA1 NOS1 RHOA
12 multicellular organismal response to stress GO:0033555 9.43 NOS1 PRL
13 positive regulation of prostaglandin secretion GO:0032308 9.37 EDN1 OXT
14 arginine catabolic process GO:0006527 9.32 NOS1 NOS3
15 negative regulation of hydrolase activity GO:0051346 9.26 NOS1 NOS3
16 negative regulation of blood pressure GO:0045776 9.13 NOS1 NOS3 OXT
17 regulation of systemic arterial blood pressure by endothelin GO:0003100 8.8 EDN1 NOS3 RHOA

Molecular functions related to Sexual Disorder according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 9.61 EDN1 OXT PRL
2 FMN binding GO:0010181 9.4 NOS1 NOS3
3 cGMP binding GO:0030553 9.37 PDE5A PRKG1
4 arginine binding GO:0034618 9.32 NOS1 NOS3
5 cadmium ion binding GO:0046870 9.26 NOS1 NOS3
6 NADPH-hemoprotein reductase activity GO:0003958 9.16 NOS1 NOS3
7 tetrahydrobiopterin binding GO:0034617 8.96 NOS1 NOS3
8 nitric-oxide synthase activity GO:0004517 8.62 NOS1 NOS3

Sources for Sexual Disorder

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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