Aliases & Classifications for Sexual Disorder

MalaCards integrated aliases for Sexual Disorder:

Name: Sexual Disorder 12 14
Sexual Dysfunction 69

Classifications:



External Ids:

Disease Ontology 12 DOID:0060043

Summaries for Sexual Disorder

Disease Ontology : 12 A disease of mental health that involves the impairment in normal sexual functioning.

MalaCards based summary : Sexual Disorder, also known as sexual dysfunction, is related to progressive black carbon hyperpigmentation of infancy and ileocolitis, and has symptoms including decreased libido and increased libido. An important gene associated with Sexual Disorder is PDE5A (Phosphodiesterase 5A), and among its related pathways/superpathways are Vascular smooth muscle contraction and Platelet homeostasis. The drugs Felodipine and Irbesartan have been mentioned in the context of this disorder. Affiliated tissues include prostate, testes and brain, and related phenotypes are cardiovascular system and nervous system

Wikipedia : 72 Sexual dysfunction (or sexual malfunction or sexual disorder) is difficulty experienced by an individual... more...

Related Diseases for Sexual Disorder

Diseases related to Sexual Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 48)
id Related Disease Score Top Affiliating Genes
1 progressive black carbon hyperpigmentation of infancy 10.7 EDN1 NOS3
2 ileocolitis 10.6 ALDH7A1 NOS1 NOS3
3 polyneuropathy 10.6 HTR1A SHBG
4 conjunctival degeneration 10.6 HTR1A PDE5A SHBG
5 47,xyy syndrome 10.6 NOS1 NOS3 PRL
6 endometriosis 10.5 KLK3 PRL SHBG
7 traumatic glaucoma 10.5 EDN1 NOS3 PDE5A
8 renovascular hypertension 10.5 EDN1 NOS1 NOS3
9 glioblastoma proneural subtype 10.5 KLK3 PRL SHBG
10 hepatocellular adenoma 10.5 ACE NOS3 PDE5A
11 retroperitoneal sarcoma 10.5 NOS3 PRL SHBG
12 capillary disease 10.5 KLK3 PRL SHBG
13 atrial septal defect 7, with or without av conduction defects 10.4 ACE KCNMA1
14 aortopulmonary window 10.4 ACE EDN1 NOS3
15 plague 10.4 KLK3 PRL SHBG
16 lymphadenitis 10.4 ACE EDN1 NOS3
17 acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22) 10.4 ACE EDN1 NOS3
18 renal fibrosis 10.4 ACE EDN1 NOS3
19 retinitis pigmentosa 19 10.4 ALDH7A1 KCNMA1
20 pyelonephritis 10.3 ACE EDN1 NOS3
21 clitoris cancer 10.3 ACE NOS3
22 diabetic encephalopathy 10.3 ACE EDN1 NOS3
23 periampullary adenoma 10.3 ACE EDN1 NOS3
24 joint disorders 10.3 ACE EDN1 NOS3 PDE5A
25 calcinosis 10.3 ACE EDN1 KLK3
26 bernard-soulier syndrome, type a2 10.3 ACE EDN1 NOS3 PDE5A
27 survival motor neuron spinal muscular atrophy 10.2 ACE NOS3 PRL SHBG
28 temporomandibular ankylosis 10.2 ACE EDN1 PRL
29 uterine corpus adenocarcinofibroma 10.1 OXT PRL SHBG
30 ulceroglandular tularemia 10.1 OXT SHBG
31 spondylolysis 10.1 OXT PRL SHBG
32 indeterminate leprosy 10.1 EDN1 NOS3
33 senile ectropion 10.0 OXT PRL
34 personality disorder 10.0 HTR1A OXT PDE5A
35 avoidant personality disorder 9.9 KLK3 OXT PRL SHBG
36 chronic conjunctivitis 9.9 HTR1A NOS1 OXT PRL
37 anogenital venereal wart 9.9 ACE EDN1 PDE4A
38 epithelial predominant pulmonary blastoma 9.8 ACE ALDH7A1 NOS3 PDE4A PDE5A
39 aicardi-goutieres syndrome 2 9.6 HTR1A OXT PRL
40 prostatic hypertrophy 9.5
41 social phobia 9.5
42 fetishism 9.5
43 gynecomastia 9.5
44 premature ejaculation 9.5
45 prostatitis 9.5
46 lubani-al saleh-teebi syndrome 9.2 ACE EDN1 NOS3 PDE4A PDE5A RHOA
47 viral hepatitis 8.8 ALDH7A1 EDN1 KCNMA1 KLK3 NOS1 NOS3
48 munchausen by proxy 4.4 ACE ALDH7A1 EDN1 HTR1A KCNMA1 KLK3

Graphical network of the top 20 diseases related to Sexual Disorder:



Diseases related to Sexual Disorder

Symptoms & Phenotypes for Sexual Disorder

UMLS symptoms related to Sexual Disorder:


decreased libido, increased libido

MGI Mouse Phenotypes related to Sexual Disorder:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.91 ACE EDN1 HTR1A KCNMA1 NOS1 NOS3
2 nervous system MP:0003631 9.9 EDN1 HTR1A KCNMA1 NOS1 NOS3 OXT
3 normal MP:0002873 9.56 EDN1 NOS1 NOS3 PRKG1 RHOA SEPT3
4 renal/urinary system MP:0005367 9.17 ACE EDN1 KCNMA1 NOS1 NOS3 OXT

Drugs & Therapeutics for Sexual Disorder

Drugs for Sexual Disorder (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 787)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Felodipine Approved, Investigational Phase 4 72509-76-3 3333
2
Irbesartan Approved, Investigational Phase 4 138402-11-6 3749
3
Metoprolol Approved, Investigational Phase 4 37350-58-6, 51384-51-1 4171
4
Aripiprazole Approved, Investigational Phase 4 129722-12-9 60795
5
Dopamine Approved Phase 4,Phase 2,Phase 3,Phase 1 51-61-6, 62-31-7 681
6
Risperidone Approved, Investigational Phase 4,Phase 3 106266-06-2 5073
7
Methyltestosterone Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 58-18-4 6010
8
Testosterone Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 58-22-0 6013
9
Nebivolol Approved, Investigational Phase 4 152520-56-4, 99200-09-6, 118457-14-0 71301
10
Tadalafil Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 171596-29-5 110635
11
Bupivacaine Approved, Investigational Phase 4,Phase 1 2180-92-9, 38396-39-3 2474
12
Triamcinolone Approved, Vet_approved Phase 4 124-94-7 31307
13
Benzocaine Approved Phase 4,Phase 3,Phase 2 1994-09-7, 94-09-7 2337
14
Drospirenone Approved Phase 4,Phase 3,Phase 2 67392-87-4 68873
15
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 50-28-2 5757
16
Ethinyl Estradiol Approved Phase 4,Phase 3,Phase 2,Phase 1 57-63-6 5991
17
Azithromycin Approved Phase 4,Phase 3,Phase 2 83905-01-5 55185 53477736 447043
18
Prednisone Approved, Vet_approved Phase 4,Phase 2,Phase 1 53-03-2 5865
19
Acetylcholine Approved Phase 4,Phase 3,Phase 2,Phase 1 51-84-3 187
20
Povidone Approved Phase 4 9003-39-8
21 Povidone-iodine Approved Phase 4 25655-41-8
22
Letrozole Approved, Investigational Phase 4,Phase 3,Phase 2 112809-51-5 3902
23
Acetylcysteine Approved, Investigational Phase 4,Phase 1,Phase 2 616-91-1 12035
24
Ezetimibe Approved Phase 4 163222-33-1 150311
25
Alfuzosin Approved, Investigational Phase 4,Phase 3 81403-80-7 2092
26
Cyproterone Acetate Approved, Investigational Phase 4,Phase 3 427-51-0
27
Menthol Approved Phase 4,Phase 3,Phase 2 2216-51-5 16666
28
Tamoxifen Approved Phase 4,Phase 3,Phase 2 10540-29-1 2733526
29
Methylphenidate Approved, Investigational Phase 4,Phase 1 113-45-1 4158
30
Citalopram Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 59729-33-8 2771
31
Lamivudine Approved, Investigational Phase 4,Phase 3 134678-17-4 60825
32
Zidovudine Approved Phase 4,Phase 3 30516-87-1 35370
33
Lopinavir Approved Phase 4,Phase 3 192725-17-0 92727
34
Ritonavir Approved, Investigational Phase 4,Phase 3,Phase 1 155213-67-5 392622
35
Histamine Approved, Investigational Phase 4,Phase 2,Phase 1 75614-87-8, 51-45-6 774
36
Methamphetamine Approved, Illicit Phase 4,Phase 2,Phase 3,Phase 1 537-46-2 10836
37
Progesterone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 57-83-0 5994
38
Estrone Approved Phase 4,Phase 2,Phase 1 53-16-7 5870
39
Lidocaine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 137-58-6 3676
40
Ethanol Approved Phase 4,Phase 2,Phase 3,Phase 1 64-17-5 702
41
Buprenorphine Approved, Illicit, Investigational, Vet_approved Phase 4,Phase 2,Phase 1 52485-79-7 40400 644073
42
Guaifenesin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 93-14-1 3516
43
Heroin Approved, Illicit Phase 4,Phase 3,Phase 2,Phase 1 561-27-3 5462328
44
Methadone Approved Phase 4,Phase 3,Phase 1,Phase 2 76-99-3 4095
45
Alprostadil Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 745-65-3 149351
46
Ropinirole Approved, Investigational Phase 4 91374-20-8, 91374-21-9 5095 497540
47
Tiagabine Approved Phase 4 115103-54-3 60648
48
Zinc Approved Phase 4,Phase 1,Phase 2 7440-66-6 32051 23994
49
Udenafil Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 268203-93-6 6918523
50
Bupropion Approved Phase 4,Phase 2,Phase 3,Phase 1 34841-39-9, 34911-55-2 444

Interventional clinical trials:

(show top 50) (show all 2382)

id Name Status NCT ID Phase Drugs
1 Clinical Study to Assess the Influence of a Saw Palmetto Preparation in Patients With Benign Prostatic Hyperplasia (BPH) and Sexual Dysfunctions Unknown status NCT01021267 Phase 4 Saw palmetto berry extract
2 Combined Antihypertensive Therapy and Sexual Dysfunction Unknown status NCT01238705 Phase 4 Felodipine add Irbesartan;Felodipine add Metoprolol
3 A Multicenter Study to Evaluate the Effects of Switching to Aripiprazole 12 Weeks on the Sexual Dysfunction From Risperidone or Paliperidone in Patients With Schizophrenia Spectrum Disorders or Bipolar Spectrum Disorders Unknown status NCT01742390 Phase 4 Aripiprazole;risperidone or paliperidone
4 Effect of Sildenafil on Quality of Sexual Life in Mild to Normally Sexually Functioning Males Unknown status NCT00313898 Phase 4 sildenafil (viagra)
5 Functional Outcome After Groin Hernia Mesh Repair: Open Versus Laparoscopy Unknown status NCT00625534 Phase 4
6 Testosterone Patch's Effects on the Cardiovascular System and Libido Unknown status NCT01208038 Phase 4 Intrinsa Transdermal testosterone patch
7 Safety and Clinical Effectiveness of 2 Lower Dose Combined PDE5i's vs. Single Maximal Dose PDE5i Unknown status NCT00498680 Phase 4 Sildenafil, Vardenafil;Sildenafil;Vardenafil;Sildenafil & Vardenafil
8 Nebivolol Effects on Endothelial Function and Erectile Function Unknown status NCT01885988 Phase 4 Nebivolol;Sugar Pill
9 Evaluation of Safety and Effectiveness of 2 Lower Dose Combined PDE5i's Versus Single Maximal Dose PDE5i Treatment Unknown status NCT01364701 Phase 4 Sildenafil 100 mg;Tadalafil 20 mg;Combination half of maximal dose for sildenafil & tadalafil
10 Treatment of Erectile Dysfunction in Hypogonadal Men With Testosterone Undecanoate Unknown status NCT00555087 Phase 4 Testosterone Undecanoate and/or PDE-5
11 Trigger Point Injections and Pelvic Rehabilitation for the Treatment of Pelvic Floor Myalgia and Sexual Pain Unknown status NCT02022722 Phase 4 Trigger Point Injections Triamcinolone Acetonide, Bupivacaine Hydrochloride
12 Effect of Vardenafil on Erectile Dysfunction and Portal Hemodynamics in Patients With Liver Cirrhosis Unknown status NCT02344823 Phase 4 Vardenafil;Placebo intake once daily
13 A Study to Evaluate the Efficacy and Safety of Vardenafil in Men With Erectile Dysfunction Caused by Spinal Cord Injury Unknown status NCT00725790 Phase 4 Vardenafil;Placebo
14 Continuous Versus Cyclic Oral Contraceptives for Endometriosis Unknown status NCT02237131 Phase 4 Oral contraceptives cyclic;Oral contraceptives continuous
15 Can Hyperbaric Oxygen Improve Erectile Function Following Surgery for Prostate Cancer Unknown status NCT00906269 Phase 4 Sildenafil therapy plus post-NSRRP HBO2T;Sildenafil therapy plus sham post-NSRRP HBO2T
16 Weight Reduction Alone May Not be Sufficient to Maintain Disease Remission in Obese Patients With Psoriasis Unknown status NCT01439425 Phase 4
17 A Prospective, Placebo Controlled, Double-Blind, Cross-over Study on the Effects of a Probiotic Preparation (VSL#3) on Metabolic Profile, Intestinal Permeability, Microbiota, Cytokines and Chemokines Expression and Other Inflammatory Markers in Pediatric Unknown status NCT01632462 Phase 4 VSL#3
18 Female Sexual Function and Back Pain Unknown status NCT01420276 Phase 4
19 The Efficacy of Prednisone and Azithromycin in the Treatment of Patients With Cat Scratch Disease Unknown status NCT01469702 Phase 4 prednison and azithromycin;prednison, azithromycin;prednison, Azenil
20 Botox on Vulvar Vestibulitis Unknown status NCT00119886 Phase 4 Botulinum toxin
21 Immunogenicity of Influenza Vaccines in HIV-infected Persons in Thailand Unknown status NCT01538940 Phase 4
22 Primary and Secondary Prevention of Human Papillomavirus (HPV) Disease in China Unknown status NCT01021904 Phase 4
23 Sex Steroids in Sjögren's Syndrome: Effect of Substitution Treatment on Fatigue Unknown status NCT00543166 Phase 4 dehydroepiandrosterone
24 Efficacy and Safety of Pulsatile Gonadotropin Releasing Hormone Pump Treatment in Patients With Idiopathic Hypogonadotropic Hypogonadism Unknown status NCT02310074 Phase 4 Pulsatile Gonadotropin Releasing Hormone;Human chorionic gonadotropin;Urinary Follicle-Stimulating Hormone
25 Odense Androgen Study - The Effect of Testim and Training in Hypogonadal Men Unknown status NCT00700024 Phase 4 Testim;placebo
26 A Prospective Trial of Povidone-iodine Suppository Before Transrectal Ultrasound Guided Prostate Biopsy Unknown status NCT02245334 Phase 4 Povidone-Iodine
27 Evaluation of Predictive Factors Regarding the Effectivity of Aromatase Inhibitor Therapy (PreFace) Unknown status NCT01908556 Phase 4 Letrozole
28 Comparative Study of Mesh Versus No Mesh in Prolapse Surgery Unknown status NCT00153257 Phase 4
29 Anti-Oxidant Effect on Peritoneal Membrane in Peritoneal Dialysis (PD) Patients Unknown status NCT01111422 Phase 4 N-acetylcysteine
30 A Study Evaluating the Effects of Lipid Lowering Treatment on Steroid Synthesis Unknown status NCT00433823 Phase 4 Atorvastatin, Ezetimibe
31 Treating Sexual Dysfunction From Selective Serotonin Reuptake Inhibitor (SSRI) Medication: a Study Comparing Requip CR to Placebo Completed NCT00334048 Phase 4 Ropinirole (Requip)
32 Switching From an SSRI to Tiagabine(GABITRIL) in Order to Alleviate SSRI Induced Sexual Dysfunction Completed NCT00174850 Phase 4 Gaitril
33 Study of Sildenafil for Treatment of SSRI-Antidepressant Sexual Dysfunction in Women Completed NCT00375297 Phase 4 sildenafil
34 PRILIGY Usage Patterns in Selected Populations Completed NCT01273545 Phase 4 PRILIGY (dapoxetine hydrochloride)
35 Statin Lowering Testosterone and Sexual Function Completed NCT02612714 Phase 4 Rosuvastatin
36 An Observational Study of Men With Premature Ejaculation Who Are Treated With Dapoxetine Hydrochloride or Alternate Care Defined as Any Treatment Other Than Dapoxetine Hydrochloride Completed NCT01021670 Phase 4 Dapoxetine hydrochloride
37 Levitra (Vardenafil, BAY38-9456) Partner Satisfaction Study II Completed NCT00377793 Phase 4 Levitra (Vardenafil, BAY38-9456);Placebo
38 Effects of Tribulus Terrestris in Women With Hypoactive Sexual Desire Disorder Completed NCT01971099 Phase 4 tribulus terrestris
39 Daily Tadalafil on Body Fat and Lean Mass Completed NCT02554045 Phase 4 Tadalafil;Placebo
40 Effects of Tribulus Terrestris in Postmenopausal Women With Hypoactive Sexual Desire Disorder Completed NCT01975649 Phase 4 Tribulus Terrestris
41 SAMBA: Sexuality And Management of Benign Prostatic Hyperplasia With Alfuzosin Completed NCT00486785 Phase 4 Alfuzosin
42 Exploratory CSII Trial on Erectile Dysfunction in T2DM Patients Completed NCT01468519 Phase 4 Insulin;Insulin
43 The Efficacy of Penile Rehabilitation Using Udenafil After Total Mesorectal Excision of Rectal Cancer Completed NCT01421940 Phase 4 Placebo drug;Udenafil
44 Sexual Functioning Study With Antidepressants Completed NCT00316160 Phase 4 Bupropion Hydrochloride Extended-release;Extended-release Venlafaxine
45 Effects of Korean Red Ginseng on Semen Parameters in Male Infertility Patients: a Randomized, Placebo-controlled, Double-blind Clinical Study Completed NCT02204826 Phase 4 Korean Red Ginseng (KRG)
46 Comparing Effects of Diet, With or Without Exercise, on Sexual, Urinary and Endothelial Function, Inflammatory Profile and Quality of Life in Obese Men Completed NCT01642576 Phase 4
47 Effects of Diet-induced Weight Loss in Obese Men Completed NCT01554865 Phase 4
48 Effects of Lifestyle-modification Induced Weight Loss on Sexual and Urinary Function, and Quality of Life in Obese Men Completed NCT01554735 Phase 4
49 Wellbutrin XL Effects on SSRIs Induced Changes Completed NCT00456820 Phase 4 Wellbutrin XL
50 Effects of Tribulus Terrestris on Sexual Function in Post-menopausal Women Completed NCT01407445 Phase 4 Placebo;Tribulus terrestris

Search NIH Clinical Center for Sexual Disorder

Genetic Tests for Sexual Disorder

Anatomical Context for Sexual Disorder

MalaCards organs/tissues related to Sexual Disorder:

39
Prostate, Testes, Brain, Heart, Bone, Liver, Spinal Cord

Publications for Sexual Disorder

Articles related to Sexual Disorder:

(show all 20)
id Title Authors Year
1
Technological change and sexual disorder. ( 27028747 )
2016
2
Hebephilia as a sexual disorder. ( 25723776 )
2015
3
Sexual disorder improvement: a target or a way in treatment of fibromyalgia. A case report and brief review. ( 19802653 )
2010
4
Drug treatment of paraphilic and nonparaphilic sexual disorders. ( 19243704 )
2009
5
Male sexuality and psychological trauma: soldiers and sexual disorder in World War I and Weimar Germany. ( 19260157 )
2008
6
Finasteride: new indication. Benign prostatic hypertrophy: sexual disorders. ( 17724838 )
2007
7
Comorbidity between social phobia and premature ejaculation: study on 242 males affected by sexual disorders. ( 16418108 )
2006
8
Treatment of paraphilic sexual disorder: the use of topiramate in fetishism. ( 16687996 )
2006
9
[The significance of the androgen-estrogen ratios in the clinical picture of sexual disorders in men]. ( 10878975 )
2000
10
Female hypoactive sexual disorder: case studies of physiologic androgen replacement. ( 10407790 )
1999
11
SEIZURE RELATED SEXUAL DISORDER. ( 28775613 )
1999
12
Pharmacological era in the treatment of sexual disorder. ( 9611685 )
1998
13
Gynecomastia and sexual disorders after the administration of omeprazole. ( 7771409 )
1995
14
Neurotransmitter, opiodergic system, steroid-hormone interaction and involvement in the replacement therapy of sexual disorders. ( 1979499 )
1990
15
Interruption in the maintenance of compulsive sexual disorder: two case studies. ( 3219064 )
1988
16
Treatment of sexual disorder: a prophylaxis for major pathology? ( 3820157 )
1987
17
Dyspareunia; a symptom of sexual disorder in the female. ( 1043847 )
1976
18
A note on avoidance conditioning techniques in sexual disorder. ( 5853245 )
1965
19
SEXUAL DISORDER IN POSTTRAUMATIC AND POSTCONCUSSIONAL STATES. ( 14128413 )
1964
20
Sexual disorder in 'mepacrine psychoses'. ( 15412077 )
1950

Variations for Sexual Disorder

Expression for Sexual Disorder

Search GEO for disease gene expression data for Sexual Disorder.

Pathways for Sexual Disorder

GO Terms for Sexual Disorder

Cellular components related to Sexual Disorder according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 caveola GO:0005901 8.8 KCNMA1 NOS1 NOS3

Biological processes related to Sexual Disorder according to GeneCards Suite gene sharing:

(show all 16)
id Name GO ID Score Top Affiliating Genes
1 positive regulation of cardiac muscle hypertrophy GO:0010613 9.56 EDN1 PDE5A
2 regulation of sodium ion transport GO:0002028 9.55 NOS1 NOS3
3 regulation of blood vessel size GO:0050880 9.54 EDN1 NOS3
4 regulation of blood pressure GO:0008217 9.54 ACE EDN1 NOS3
5 vasoconstriction GO:0042310 9.52 EDN1 HTR1A
6 nitric oxide mediated signal transduction GO:0007263 9.51 NOS1 NOS3
7 positive regulation of renal sodium excretion GO:0035815 9.49 EDN1 OXT
8 nitric oxide biosynthetic process GO:0006809 9.48 NOS1 NOS3
9 negative regulation of calcium ion transport GO:0051926 9.46 NOS1 NOS3
10 positive regulation of guanylate cyclase activity GO:0031284 9.43 NOS1 NOS3
11 negative regulation of potassium ion transport GO:0043267 9.4 NOS1 NOS3
12 positive regulation of prostaglandin secretion GO:0032308 9.32 EDN1 OXT
13 arginine catabolic process GO:0006527 9.26 NOS1 NOS3
14 negative regulation of hydrolase activity GO:0051346 9.16 NOS1 NOS3
15 regulation of systemic arterial blood pressure by endothelin GO:0003100 8.96 EDN1 NOS3
16 negative regulation of blood pressure GO:0045776 8.8 NOS1 NOS3 OXT

Molecular functions related to Sexual Disorder according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 9.61 EDN1 OXT PRL
2 cGMP binding GO:0030553 9.4 PDE5A PRKG1
3 FMN binding GO:0010181 9.37 NOS1 NOS3
4 arginine binding GO:0034618 9.32 NOS1 NOS3
5 cadmium ion binding GO:0046870 9.26 NOS1 NOS3
6 NADPH-hemoprotein reductase activity GO:0003958 9.16 NOS1 NOS3
7 tetrahydrobiopterin binding GO:0034617 8.96 NOS1 NOS3
8 nitric-oxide synthase activity GO:0004517 8.62 NOS1 NOS3

Sources for Sexual Disorder

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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