MCID: SHG001
MIFTS: 53

Shigellosis malady

Categories: Rare diseases, Infectious diseases, Gastrointestinal diseases

Aliases & Classifications for Shigellosis

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Sources:
2CDC, 11Disease Ontology, 13DISEASES, 29ICD10, 30ICD10 via Orphanet, 31ICD9CM, 38MeSH, 47NIH Rare Diseases, 49Novoseek, 53Orphanet, 61SNOMED-CT, 67UMLS, 68UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Shigellosis:

Name: Shigellosis 11 47 53 49 2 13
Dysentery, Bacillary 38 67
Shigella Flexneri Infectious Disease 11
Shigella Sonnei Infectious Disease 11
 
Shigella Boydii Infectious Disease 11
Shigella Gastroenteritis 11
Bacillary Dysentery 11
Shigella Infections 67

Characteristics:

Orphanet epidemiological data:

53
shigellosis:
Inheritance: Not applicable; Prevalence: 1-9/100000 (Europe); Age of onset: All ages

Classifications:



External Ids:

Disease Ontology11 DOID:12385
MeSH38 D004405
Orphanet53 ORPHA810
ICD10 via Orphanet30 A03.8, A03.9, A03.0 A03.2, A03.1, A03.3, more
UMLS via Orphanet68 C0013371

Summaries for Shigellosis

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Disease Ontology:11 A primary bacterial infectious disease that results in infection located in epithelium of colon, has material basis in Shigella boydii, has material basis in Shigella dysenteriae, has material basis in Shigella flexneri, or has material basis in Shigella sonnei, which produce toxins that can attack the lining of the large intestine, causing swelling, ulcers on the intestinal wall, and bloody diarrhea. The bacteria are transmitted by ingestion of food and water contaminated with feces.

MalaCards based summary: Shigellosis, also known as dysentery, bacillary, is related to flinders island spotted fever and maligant granulosa cell tumor of ovary. An important gene associated with Shigellosis is CASP1 (Caspase 1), and among its related pathways are Atypical NF-kappaB pathway and Signaling events mediated by VEGFR1 and VEGFR2. The drugs loperamide hydrochloride and bismuth hydroxide have been mentioned in the context of this disorder. Affiliated tissues include epithelium of colon, colon and t cells, and related mouse phenotypes are cardiovascular system and neoplasm.

Wikipedia:70 Shigellosis, also known as bacillary dysentery or Marlow syndrome, in its most severe manifestation, is... more...

Related Diseases for Shigellosis

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Diseases related to Shigellosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 96)
idRelated DiseaseScoreTop Affiliating Genes
1flinders island spotted fever10.4CASP1, CXCL8
2maligant granulosa cell tumor of ovary10.4CXCL8, LTA
3basidiobolomycosis10.3CXCL8, IL10
4gonadal disease10.3CXCL8, IL10
5focal embolic glomerulonephritis10.3CD79A, CXCL8
6acute interstitial pneumonia10.3CXCL8, IL10
7benign adult familial myoclonic epilepsy10.3CXCL8, IL10
8lymphangiectasia, intestinal10.2CXCL8, LTF
9infancy electroclinical syndrome10.2CXCL8, IL10
10cervical incompetence10.2CDC42, CXCL8
11chromophil adenoma of the kidney10.2IL10, LTA
12hypervitaminosis d10.2CD79A, TTR
13fallopian tube disease10.2CD79A, CXCL8
143-alpha hydroxyacyl-coa dehydrogenase deficiency10.1CXCL8, LTF
15hematocele of tunica vaginalis testis10.1CD79A, TTR
16plague10.1CD79A, TTR
17diversion colitis10.1CDC42, LTF
18neurotic excoriation10.0IL10, LTA
19pleomorphic lipoma10.0CASP1, CXCL8, IL10
20boutonneuse fever10.0CD79A, LTF
21cholera10.0
22common cold10.0CXCL8, IL10, LTA
23bacteriuria10.0CXCL8, IL10, LTA
24sialadenitis10.0CD79A, LTF
25dysentery10.0
26extrahepatic cholestasis10.0CD79A, CXCL8, TTR
27pseudoretinitis pigmentosa10.0CXCL8, IL10, LTF
28ankylosis9.9CD79A, CXCL8
29diarrhea9.9
30encephalopathy9.9
31addison's disease9.9CD79A, CXCL8, IL10
32crustacean allergy9.9CD79A, IL10
33kidney angiomyolipoma9.9CD79A, CXCL8, IL10
34vaginitis9.9CD79A, CXCL8, IL10
35geotrichosis9.9CD79A, CXCL8, IL10
36biliary tract disease9.9CD79A, CXCL8, IL10
37bone lymphoma9.9CD79A, TTR
38chronic hiccups9.9CD79A, IL10
39hemorrhagic fever with renal syndrome9.8CD79A, CXCL8, IL10
40xanthomatosis9.8CD79A, CXCL8, IL10
41hemolytic-uremic syndrome9.8
42typhoid fever9.8
43rectum leiomyosarcoma9.8CD79A, CXCL8, IL10
44laryngeal tuberculosis9.8CD79A, CXCL8, IL10
45hodgkin's lymphoma, mixed cellularity9.8CD79A, CXCL8, IL10
46congenital disorder of glycosylation, type ih9.8CD79A, CXCL8, IL10
47perianal skin paget's disease9.8CD79A, CXCL8, IL10
48palmoplantar keratosis9.8CD79A, CXCL8, IL10
49basaloid squamous cell carcinoma9.8CD79A, CXCL8, IL10
50hepatitis9.8

Graphical network of the top 20 diseases related to Shigellosis:



Diseases related to shigellosis

Symptoms for Shigellosis

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Drugs & Therapeutics for Shigellosis

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Drugs for Shigellosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 28)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Rifaximinapproved, investigationalPhase 310180621-81-46436173
Synonyms:
(2S,16Z,18E,20S,21S,22R,23R,24R,25S,26S,27S,28E)-5,6,21,23,25 Pentahydroxy-27-methoxy-2,4,11,16,20,22,24,26-octamethyl-2,7-(epoxypentadeca(1,11,13)trienimino)benzofuro(4,5-e)pyrido(1,2-a)benzimidazole-1,15(2H)-dione, 25-acetate
4-Deoxy-4'-methylpyrido(1',2'-1,2)imidazo(5,4-c)rifamycin SV
4-deoxy-4'-methylpyrido(1',2'-1,2)imidazo(5,4C)rifamycin
80621-81-4
88747-56-2
AC-19112
BRN 3584528
Bio-0556
C43H51N3O11
CHEMBL1617
D02554
DB01220
Fatroximin
Flonorm
L 105
L 105 (Ansamacrolide antibiotic)
L 105SV
LS-178059
LS-64147
Lormyx
Lumenax
MLS000759430
Normix
RedActiv
 
Rifacol
Rifamixin
Rifamycin L 105
Rifamycin L 105SV
Rifaxidin
Rifaximin
Rifaximin (USAN/INN)
Rifaximin [USAN:INN]
Rifaximina
Rifaximina [Spanish]
Rifaximine
Rifaximine [French]
Rifaximinum
Rifaximinum [Latin]
Rifaximinun
Rifaxin
Ritacol
S1790_Selleck
SMR000466324
Spiraxin
UNII-L36O5T016N
Xifaxan
Xifaxan, Rifacol, Fatroximin, Rifaximin
Xifaxsan
Xifaxsan (TN)
alpha-0817185
2
ZincapprovedPhase 322317440-66-632051, 23994
Synonyms:
30Zn
Cinc
Zinc
Zinc ion
 
Zincum
Zink
Zn
Zn(ii)
Zn2+
3Anti-Bacterial AgentsPhase 3, Phase 210884
4Nucleic Acid Synthesis InhibitorsPhase 34855
5RifamycinsPhase 397
6AntibodiesPhase 36045
7Gastrointestinal AgentsPhase 3, Phase 18109
8rifamycin SVPhase 397
9Anti-Infective AgentsPhase 3, Phase 221402
10ImmunoglobulinsPhase 36045
11MicronutrientsPhase 35802
12VaccinesPhase 3, Phase 2, Phase 16428
13Trace ElementsPhase 35802
14
Histamine PhosphateapprovedPhase 2103351-74-165513
Synonyms:
1H-Imidazole-4-ethanamine, phosphate (1:2)
2-Imidazol-4-ylethylamine orthophosphoric acid (1:2)
4-(2-Aminoethyl)imidazole bis(dihydrogen phosphate)
4-(2-Aminoethyl)imidazole di-acid phosphate
4-2(2-Aminoethyl)Imidazole-Di-Acid Phosphate
51-74-1
53623-99-7
74-56-6
AC1L23E4
CID65513
D04445
DB00667
 
EINECS 200-118-4
H0147
Histamine acid phosphate
Histamine biphosphate
Histamine dihydrogen phosphate
Histamine diphosphate
Histamine phosphate (1:2)
Histamine phosphate (TN)
Histamine phosphate (USP)
Histamine phosphate [USP]
Histamine positive
Histaminum
LS-78569
UNII-QWB37T4WZZ
15
HistamineapprovedPhase 2103475614-87-8, 51-45-6774
Synonyms:
.beta.-Imidazolyl-4-ethylamine
1H-Imidazole-4-ethanamine
1H-Imidazole-5-ethanamine
1avn
1qft
2-(1H-Imidazol-4-yl)ethanamine
2-(1H-Imidazol-4-yl)ethylamine
2-(1H-Imidazol-5-yl)ethanamine
2-(1H-Imidazol-5-yl)ethylamine
2-(1H-imidazol-4-yl)ethan-1-amine
2-(1H-imidazol-5-yl)ethanamine
2-(3H-Imidazol-4-yl)-ethylamine
2-(4-Imidazolyl)ethanamine
2-(4-Imidazolyl)ethylamine
2-Imidazol-4-yl-Ethylamine
2-Imidazol-4-ylethylamine
2-[4-Imidazolyl]ethylamine
4-(2-Aminoethyl)-1H-imidazole
4-(2-Aminoethyl)imidazole
4-Imidazoleethylamine
5-Imidazoleethylamine
51-45-6
53290_FLUKA
64422-25-9
924364-91-0
AC-13185
AC1L19ZT
AC1Q54BV
AC1Q54BW
AKOS000274386
ALBB-005968
BCBcMAP01_000250
BSPBio_001117
BSPBio_002124
Bio1_000487
Bio1_000976
Bio1_001465
Bio2_000389
Bio2_000869
C00388
CCRIS 6535
CHEBI:18295
CHEMBL90
CID774
D08040
DivK1c_000308
EINECS 200-100-6
Eramin
Ergamine
Ergotidine
F411C768-A159-4FC0-A195-291A08BB03AA
Free histamine
H7125_SIGMA
HMS1362G19
HMS1792G19
HMS1990G19
HSDB 3338
HSM
Histamine
Histamine (DCF)
Histamine Base
Histamine [USAN]
Histamine, Free Base
Histaminum
 
Histaminum (TN)
IDI1_000308
IDI1_002144
Imidazole-4-ethylamine
Istamina
Istamina [Italian]
KBio1_000308
KBio2_000457
KBio2_001325
KBio2_003025
KBio2_003893
KBio2_005593
KBio2_006461
KBio3_000853
KBio3_000854
KBio3_001344
KBioGR_000457
KBioGR_001580
KBioSS_000457
KBioSS_001325
L-Histamin base
L-Histamine
L-histamine
L000292
LS-75835
Lopac-H-7250
Lopac0_000595
MLS000069447
MolPort-001-785-597
MolPort-002-042-264
NCGC00015513-01
NCGC00015513-08
NCGC00093371-02
NCGC00093371-03
NCGC00093371-04
NCGC00093371-05
NINDS_000308
NSC 33792
NSC33792
SDCCGMLS-0066601.P001
SMP1_000151
SMR000059091
SPBio_000729
ST073926
STK346752
STOCK5S-55669
Spectrum2_000665
Spectrum3_000452
Spectrum4_000960
Spectrum5_000796
Spectrum_000845
Theramine
UNII-820484N8I3
WLN: T5M CNJ D2Z
ZERO/004089
[3H]histamine
b-Imidazolyl-4-ethylamine
beta-Aminoethylglyoxaline
beta-Aminoethylimidazole
beta-Aminothethylglyoxaline
beta-Imidazolyl-4-ethylamine
beta-aminothethylglyoxaline
bmse000744
histamine
nchembio.87-comp54
nchembio714-comp1
16
butyric acidexperimentalPhase 2363107-92-6264
Synonyms:
1-Butanoate
1-Butanoic acid
1-Butyrate
1-Butyric acid
1-Propanecarboxylate
1-Propanecarboxylic acid
Butanate
Butanic acid
Butanoate
Butanoic acid
Buttersaeure
Butyrate
 
Butyric acid
Ethylacetate
Ethylacetic acid
Honey robber
Kyselina maselna
N-Butanoate
N-Butanoic acid
N-Butyrate
N-Butyric acid
Propanecarboxylate
Propanecarboxylic acid
Propylformate
Propylformic acid
17Antibiotics, AntitubercularPhase 26972
18Histamine AntagonistsPhase 2946
19Pharmaceutical SolutionsPhase 27793
20Neurotransmitter AgentsPhase 217734
21
Aluminum hydroxideapprovedPhase 120121645-51-2
Synonyms:
Al(OH)3
Aluminium hydroxide
Aluminium hydroxide gel, dried
 
Aluminium hydroxide, dried
Aluminum hydroxide gel, dried
Aluminum hydroxide, dried
Dried aluminium hydroxide
Dried aluminum hydroxide gel
22Anti-Ulcer AgentsPhase 11767
23AntacidsPhase 11767
24Adjuvants, ImmunologicPhase 12484
25Aluminum sulfatePhase 187
26
Formaldehydeapproved, vet_approved8450-00-0712
Synonyms:
Aldeide formica
Fannoform
Formaldehyde
Formalin
Formalina
Formaline
Formalith
Formic aldehyde
Formol
 
Methaldehyde
Methanal
Methyl aldehyde
Methylene glycol
Methylene oxide
Oxomethane
Oxomethylene
Oxymethylene
Paraform
Paraformaldehyde
27Disinfectants547
28Ether60

Interventional clinical trials:

(show all 35)
idNameStatusNCT IDPhase
1Safety, Immunogenicity and Efficacy of Shigella Conjugate Vaccines in 1-4 Year Olds in IsraelCompletedNCT00368316Phase 3
2Zinc Supplementation in Shigella PatientsCompletedNCT00321126Phase 3
3Rifaximin for Prevention of Travellers' DiarrheaCompletedNCT00742469Phase 3
4Therapeutic Induction of Endogenous AntibioticsCompletedNCT00800930Phase 2
5Healthy Adult Volunteer Study for Two Doses of a Shigella VaccineCompletedNCT00210288Phase 2
6Shigella Flexneri 2a Invaplex 50 Vaccine Dose Finding and Assessment of ProtectionCompletedNCT00485134Phase 1, Phase 2
7Safety and Efficacy Study of WRSS1, a Shigella Sonnei Vaccine CandidateCompletedNCT01080716Phase 1, Phase 2
8A Study of the Safety and Immune Response of 2 Doses of a New Shigella Vaccine in Kenyan AdultsActive, not recruitingNCT02676895Phase 2
9Phase 2b Challenge Study With the Bioconjugate Vaccine Flexyn2aActive, not recruitingNCT02646371Phase 2
10Safety and Efficacy Challenge Study of CVD 1208S, a Live, Attenuated Oral Vaccine to Prevent Shigella: Phase IIbTerminatedNCT00866242Phase 2
11Safety and Efficacy Study of CVD 1208S, a Live, Attenuated Oral Vaccine to Prevent Shigella Infection: Phase IIaTerminatedNCT00866476Phase 2
12Safety and Efficacy Study of CVD 1208S, a Live, Attenuated Oral Vaccine to Prevent Shigella Infection Using cGMPCompletedNCT01531530Phase 1
13Shigella Sonnel O-SPC/rBRU Conjugate VaccineCompletedNCT01369927Phase 1
14A Phase 1, Dose Escalation Study, to Evaluate a New Shigella Sonnei Vaccine in Healthy Adults.CompletedNCT02017899Phase 1
15Evaluate a New Shigella Sonnei Vaccine Administered Either by Intradermal, Intranasal or Intramuscular Route in Healthy AdultsCompletedNCT02034500Phase 1
16Safety Study of Inactivated Shigella Whole Cell Vaccine in AdultsCompletedNCT01509846Phase 1
17Safety and Reactogenicity of Bioconjugate Vaccine to Prevent ShigellaCompletedNCT01069471Phase 1
18Safety and Immunogenicity of Two Live, Attenuated Oral Shigella Sonnei Vaccines: WRSs2 and WRSs3CompletedNCT01336699Phase 1
19Safety and Tolerability of a Bioconjugate Vaccine Against Shigella Flexneri 2aCompletedNCT02388009Phase 1
20Invaplex 50 Vaccine Dose-RangingCompletedNCT00082069Phase 1
21Effect of 15g Daily Consumption of NUTRIOSE on Healthy Volunteers Microbiota.CompletedNCT01897649Phase 1
22Safety and Immunogenicity of Artificial Invaplex (Shigella Flexneri 2a InvaplexAR) Administered Intranasally to Healthy, Adult VolunteersRecruitingNCT02445963Phase 1
23Phase 1 Study of dmLT ID Vaccination in Healthy AdultsRecruitingNCT02531685Phase 1
24Shigella Sonnei 53G ChallengeNot yet recruitingNCT02816346Phase 1
25Shigella WRSS1 Vaccine Trial in BangladeshNot yet recruitingNCT02934178Phase 1
26SF2a-TT15 Conjugate Vaccine in Healthy Adult VolunteersNot yet recruitingNCT02797236Phase 1
27Shigella Sonnei OSPC-rDT Conjugate VaccineWithdrawnNCT01399424Phase 1
28Identification of Correlates of Protection Against Shigella and Enterotoxigenic Escherichia Coli InfectionsUnknown statusNCT01638039
29A Registry Study on Xiyanping(a Chinese Medicine Injection) Used in Fifty HospitalsUnknown statusNCT01612572
30Experimental Phage Therapy of Bacterial InfectionsUnknown statusNCT00945087
31The Long Term Clinical Course of Postinfectious Irritable Bowel Syndrome After Shigellosis; A 10 Year Follow up StudyCompletedNCT02516683
32Safety Study of Live Shigella Vaccine in Bangladeshi Adults and ChildrenCompletedNCT01813071
33Evaluation of a Diagnostic Enteric Card for Management of DiarrheaCompletedNCT00736567
34Diagnosis of Neglected Tropical Diseases Among Patients With Persistent Digestive DisordersCompletedNCT02105714
35COmparison of MicroBiota AccordIng to Age in Crohn's Disease (COMeBACk)RecruitingNCT02839317

Search NIH Clinical Center for Shigellosis

Inferred drug relations via UMLS67/NDF-RT45:


Cochrane evidence based reviews: dysentery, bacillary

Genetic Tests for Shigellosis

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Anatomical Context for Shigellosis

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MalaCards organs/tissues related to Shigellosis:

35
Colon, T cells, Testes, Neutrophil, Appendix, Kidney, Brain

FMA organs/tissues related to Shigellosis:

17
Epithelium of colon

Animal Models for Shigellosis or affiliated genes

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MGI Mouse Phenotypes related to Shigellosis:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053857.9BTRC, CASP1, CRK, CTTN, IL10, LTA
2MP:00020067.9BTRC, CASP1, CD79A, IL10, LTF, SRC
3MP:00053847.1BTRC, CASP1, CD79A, CTTN, IL10, IRAK4
4MP:00053977.1BTRC, CASP1, CD79A, CTTN, IL10, IRAK4
5MP:00053877.0BTRC, CASP1, CD79A, CTTN, IL10, IRAK4
6MP:00053766.9BTRC, CASP1, CD79A, CRK, IL10, IRAK4

Publications for Shigellosis

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Articles related to Shigellosis:

(show top 50)    (show all 537)
idTitleAuthorsYear
1
Shigellosis in men who have sex with men: an overlooked opportunity to counsel with pre-exposure prophylaxis for HIV. (26945593)
2016
2
Shigellosis in Nepal: 13A years review of nationwide surveillance. (27814742)
2016
3
Shigellosis in refugees, Austria, July to November 2015. (26676065)
2015
4
Quantitative microbial risk assessment of antibacterial hand hygiene products on risk of shigellosis. (24680068)
2014
5
Cholera and shigellosis: different epidemiology but similar responses to climate variability. (25229494)
2014
6
Use of population-based surveillance to define the high incidence of shigellosis in an urban slum in Nairobi, Kenya. (23505506)
2013
7
Gastrointestinal and extra-intestinal manifestations of childhood shigellosis in a region where all four species of Shigella are endemic. (23691156)
2013
8
Characterization of Shigella sonnei in Malaysia, an increasingly prevalent etiologic agent of local shigellosis cases. (22606962)
2012
9
How we didn't clean up until we washed our hands: shigellosis in an elementary and middle school in North Texas. (22189658)
2012
10
A multi-center randomized trial to assess the efficacy of gatifloxacin versus ciprofloxacin for the treatment of shigellosis in Vietnamese children. (21829747)
2011
11
Zinc supplementation in the management of shigellosis in malnourished children in Bangladesh. (17554249)
2008
12
Comparison of cost-of-illness with willingness-to-pay estimates to avoid shigellosis: evidence from China. (18234703)
2008
13
Epidemiology of highly endemic multiply antibiotic-resistant shigellosis in children in the Peruvian Amazon. (18710884)
2008
14
Risk factors for shigellosis in Thailand. (16997593)
2006
15
Risk factors for mortality due to shigellosis: a case-control study among severely-malnourished children in Bangladesh. (16262023)
2005
16
Azithromycin as an alternative to nalidixic acid in the therapy of childhood shigellosis. (15071299)
2004
17
Laboratory-confirmed shigellosis in the United States, 1989-2002: epidemiologic trends and patterns. (15156473)
2004
18
Shigellosis: innate mechanisms of inflammatory destruction of the intestinal epithelium, adaptive immune response, and vaccine development. (15030306)
2003
19
Disease-dependent changes in T-cell populations in patients with shigellosis. (10843411)
2000
20
Shigellosis of childhood in northern Greece: epidemiological, clinical and laboratory data of hospitalized patients during the period 1971-96. (10826910)
2000
21
Shigellosis in a squirrel monkey: a clinical history. (10576630)
1999
22
Antimicrobial therapy for shigellosis: issues on antimicrobial resistance. (10211436)
1998
23
Epidemiology of shigellosis among children exposed to cases of Shigella dysentery: a multivariate assessment. (9129527)
1997
24
Prevalence of shigellosis in the U.S.: consistency with dose-response information. (8856376)
1996
25
Shigellosis: from molecular pathogenesis of infection to protective immunity and vaccine development. (9127893)
1996
26
Absorption of macronutrients from a calorie-dense diet in malnourished children during acute shigellosis. (8811519)
1996
27
Shigellosis in Thai children: experience from a rural hospital 1985-1993. (8629073)
1995
28
Epidemiological, clinical and microbiological features of shigellosis among hospitalized children in northern Israel. (7660077)
1995
29
Moose soup shigellosis in Alaska. (8048226)
1994
30
Short-course norfloxacin and trimethoprim-sulfamethoxazole treatment of shigellosis and salmonellosis in Egypt. (8074256)
1994
31
An outbreak of shigellosis in a slum colony of Delhi-1990. (8014439)
1993
32
Evaluation of an intervention program for the control of an outbreak of shigellosis among institutionalized persons. (8228351)
1993
33
Prevalence of shigellosis and other enteric pathogens in a zoologic collection of primates. (8407446)
1993
34
From the Centers for Disease Control. Shigellosis in child day care centers--Lexington-Fayette County, Kentucky, 1991. (1640601)
1992
35
Effects of a protein-rich diet during convalescence from shigellosis on catch-up growth, serum proteins, and insulin-like growth factor-I. (1287560)
1992
36
Natural immunity to shigellosis in two groups with different previous risks of exposure to Shigella is only partly expressed by serum antibodies to lipopolysaccharide. (1552217)
1992
37
Childhood shigellosis in Saudi Arabia. (1565538)
1992
38
Potentials of Shigella flexneri Y strain TSF21 as a candidate vaccine against shigellosis: safety, immunogenicity and protective efficacy in Bonnet monkeys. (1878259)
1991
39
Shigellosis in Kentucky, 1986 through 1989. (2068620)
1991
40
Epidemiologic aspects of shigellosis and other causes of dysentery in Thailand. (2047642)
1991
41
Prospective study of the association between serum antibodies to lipopolysaccharide O antigen and the attack rate of shigellosis. (1706731)
1991
42
Recurrent shigellosis complicating human immunodeficiency virus infection: failure of pre-existing antibodies to confer protection. (2642653)
1989
43
Shigellosis winter trends in Milwaukee. (2786286)
1989
44
Therapy for shigellosis. (2738789)
1989
45
An outbreak of shigellosis in central India: higher death rate in post-measles shigellosis. (2607100)
1989
46
A shigellosis outbreak traced to commercially distributed shredded lettuce. (3057879)
1988
47
Erythrocyte vacuolation in haemolytic anaemia during shigellosis. (2885569)
1987
48
The relation between production of cytotoxin and clinical features in shigellosis. (3519788)
1986
49
Incidence of shigellosis among paediatric diarrhoeal disorders (a bacteriological study). (6491334)
1984
50
Appendiceal perforation and shigellosis. (6364623)
1983

Variations for Shigellosis

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Expression for genes affiliated with Shigellosis

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Search GEO for disease gene expression data for Shigellosis.

Pathways for genes affiliated with Shigellosis

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Pathways related to Shigellosis according to KEGG:

33
id Name KEGG Source Accession
1Shigellosishsa05131

Pathways related to Shigellosis according to GeneCards Suite gene sharing:

(show all 34)
idSuper pathwaysScoreTop Affiliating Genes
19.5BTRC, SRC
2
Show member pathways
9.5CDC42, SRC, VCL
39.5CDC42, SRC, VCL
49.5CRK, SRC, VCL
59.4CDC42, CTTN, SRC
69.4CDC42, CTTN, SRC
79.4CDC42, CTTN, SRC
89.4CXCL8, IRAK4, LTA
99.4CTTN, CXCL8, SRC
10
Show member pathways
9.4CDC42, CRK, SRC
119.4CDC42, CRK, SRC
129.4CDC42, CRK, SRC
139.3CRK, CXCL8, SRC
14
Show member pathways
9.3CDC42, PFN1, VCL
159.3CDC42, IRAK4, SRC
16
Show member pathways
9.3BTRC, CASP1, IRAK4
17
Show member pathways
9.1CDC42, CXCL8, LTF, SRC
18
Show member pathways
9.1CDC42, CRK, SRC, VCL
199.1CDC42, CRK, CTTN, SRC
209.1CXCL8, IL10, VCL
21
Show member pathways
9.1CXCL8, IL10, LTA
229.0CDC42, CTTN, PFN1, VCL
23
Show member pathways
9.0CASP1, CDC42, CXCL8, PFN1
24
Show member pathways
8.9CDC42, CRK, IRAK4, SRC
258.8CDC42, CRK, CTTN, SRC, VCL
26
Show member pathways
8.8CDC42, CTTN, PFN1, SRC
27
Show member pathways
8.7CD79A, CDC42, CRK, IL10
28
Show member pathways
8.7CASP1, CXCL8, IL10, SRC
298.6CASP1, CXCL8, IL10, IRAK4
30
Show member pathways
8.5CDC42, CRK, PFN1, SRC, VCL
31
Show member pathways
8.5CDC42, CRK, PFN1, SRC, VCL
32
Show member pathways
7.5CASP1, CDC42, CRK, CXCL8, IL10, LTA
337.3BTRC, CDC42, CRK, CTTN, CXCL8, PFN1
34
Show member pathways
7.1BTRC, CASP1, CD79A, CDC42, CRK, IRAK4

GO Terms for genes affiliated with Shigellosis

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Cellular components related to Shigellosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cell-cell adherens junctionGO:00059138.6CTTN, PFN1, SRC, VCL
2cytoplasmGO:00057375.3BTRC, CD79A, CDC42, CRK, CTTN, IL10

Biological processes related to Shigellosis according to GeneCards Suite gene sharing:

(show all 9)
idNameGO IDScoreTop Affiliating Genes
1epithelial cell-cell adhesionGO:009013610.2CDC42, VCL
2branching involved in mammary gland duct morphogenesisGO:00604449.5BTRC, SRC
3response to molecule of bacterial originGO:00022379.5CXCL8, IL10
4negative regulation of growth of symbiont in hostGO:00441309.5IL10, LTA
5positive regulation of cytokine secretionGO:00507159.4CASP1, IL10, SRC
6ephrin receptor signaling pathwayGO:00480139.4CDC42, CRK, SRC
7vascular endothelial growth factor receptor signaling pathwayGO:00480109.3CDC42, CRK, SRC
8Fc-gamma receptor signaling pathway involved in phagocytosisGO:00380969.1CDC42, CRK, SRC
9cellular response to lipopolysaccharideGO:00712229.0CXCL8, IL10, SRC

Molecular functions related to Shigellosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1protein phosphorylated amino acid bindingGO:004530910.2BTRC, CRK
2cadherin binding involved in cell-cell adhesionGO:00986419.4CTTN, PFN1, SRC, VCL
3protein bindingGO:00055154.5BTRC, CASP1, CD79A, CDC42, CRK, CTTN

Sources for Shigellosis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet