MCID: SHR002
MIFTS: 64

Short Stature malady

Endocrine category

Summaries for Short Stature

Sources:
64Wikipedia, 47OMIM, 33MalaCards
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Wikipedia:64 Short stature refers to a height of a human being which is below expected. Shortness is a vague term... more...

MalaCards: Short Stature, also known as short stature due to growth hormone secretagogue receptor deficiency, is related to mental retardation and growth hormone deficiency. An important gene associated with Short Stature is GHSR (growth hormone secretagogue receptor), and among its related pathways are Signaling by GPCR and Class A/1 (Rhodopsin-like receptors). The compounds arginine and ribonucleic acid have been mentioned in the context of this disorder. Affiliated tissues include skin, kidney and whole blood, and related mouse phenotypes are homeostasis/metabolism and growth/size.

Description from OMIM:47 604271

Aliases & Classifications for Short Stature

Sources:
47OMIM, 45Novoseek, 49Orphanet, 26ICD10 via Orphanet
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Endocrine


Characteristics (Orphanet epidemiological data):

49
short stature due to growth hormone secretagogue receptor deficiency:
Inheritance: Autosomal dominant,Autosomal recessive; Prevalence: <1/1000000; Age of onset: Neonatal/infancy


Aliases & Descriptions:

short stature 47 45
short stature due to growth hormone secretagogue receptor deficiency 49
short stature due to partial growth hormone receptor deficiency 49
short stature due to partial ghr deficiency 49
short stature due to ghsr deficiency 49


External Ids:

OMIM47 604271
ICD10 via Orphanet26 E34.3

Related Diseases for Short Stature

Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases in the Short Stature family:

short stature with optic atrophy and pelger-huët anomaly syndrome

Diseases related to Short Stature via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 1187)
idRelated DiseaseScoreTop Affiliating Genes
1mental retardation31.1PTPN11, FGFR3, GHR
2growth hormone deficiency31.1IGF1, IGFBP3, IGFBP1, GH1, GHRHR, GHR
3brachydactyly30.9FGFR3
4turner syndrome30.8IGFBP1, GHR, GH1, SHOX, IGFBP3, IGF1
5dwarfism30.5IGFBP3, SHOX, GH1, GHR, GHRHR, IGF1
6noonan syndrome30.5GHR, IGFBP3, IGF1, PTPN11
7laron syndrome30.4GHR, IGFBP3, IGF1, IGFBP1, GH1
8prader-willi syndrome30.4GHRL, GH1, IGF1, GHSR
9achondroplasia30.3FGFR3, ACAN
10hypochondroplasia30.3SHOX, FGFR3
11costello syndrome30.3PTPN11
12insulin resistance30.3IGF1, IGFBP1, GHR, GHRL, GH1, IGFBP3
13arthritis30.2GHRL, CTSK, ACAN, PTPN11
14panhypopituitarism30.2GH1, GHR, IGF1
15hypoglycemia30.0GH1, IGFBP3, IGFBP1, GNRH1, IGF1, GHRL
16precocious puberty30.0IGFBP3, GNRH1, GH1, IGF1, GHR
17skeletal dysplasias30.0SHOX, FGFR3, ACAN, CTSK
18amenorrhea30.0GNRH1, IGF1
19x-linked spondyloepiphyseal dysplasia tarda30.0ACAN, FGFR3
20pycnodysostosis30.0CTSK
21werner syndrome30.0IGFBP3
22anorexia nervosa29.8IGF1, GHRL, GH1, IGFBP3, IGFBP1, GHR
23type 1 diabetes29.8IGF1, IGFBP3, IGFBP1, GH1, GHR
24acanthosis nigricans29.8FGFR3, IGF1R, IGF1
25rabson-mendenhall syndrome29.8IGFBP3, IGF1
26partial isolated growth hormone deficiency29.8GHSR, GHR
27insulin-like growth factor i deficiency29.8IGF1, GHR
28isolated growth hormone deficiency type 1b29.8GH1, GHRHR
29hepatitis c29.8PTPN11
30empty sella syndrome29.8GH1, IGF1
31donohue syndrome29.8IGF1, IGF1R
32premature ovarian failure29.8GNRH1
33neurofibromatosis29.8PTPN11
34down syndrome29.8FGFR3
35deficiency anemia29.8GHRL
36short syndrome11.0
37microcephaly10.7
38micro syndrome10.6
39n syndrome10.6
40multiple epiphyseal dysplasia10.4
41cleft palate10.4
42deafness, epiphyseal dysplasia, short stature10.4
43celiac disease10.4
44blepharophimosis with ptosis, syndactyly, and short stature10.4
45leri weill dyschondrosteosis10.4
46isolated growth hormone deficiency10.4
47subaortic stenosis short stature syndrome10.3
48floating-harbor syndrome10.3
49extrasystoles short stature hyperpigmentation microcephaly10.3
50myhre syndrome10.3

Graphical network of the top 20 diseases related to Short Stature:



Diseases related to short stature

Clinical Features for Short Stature

Sources:
47OMIM
See all sources

Clinical features from OMIM:

604271

Clinical synopsis from OMIM:

604271

Drugs & Therapeutics for Short Stature

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Short Stature

Drug clinical trials:

Search ClinicalTrials for Short Stature

Search NIH Clinical Center for Short Stature

Search CenterWatch for Short Stature

Genetic Tests for Short Stature

Anatomical Context for Short Stature

Sources:
33MalaCards
See all sources

MalaCards organs/tissues related to Short Stature:

33
Skin, Kidney, Whole blood, Heart, Skeletal muscle, Thyroid, Testis, T cells, B cells, Fetal thyroid, Pituitary

Animal Models for Short Stature or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
See all sources

Publications for Short Stature

Sources:
51PubMed
See all sources

Articles related to Short Stature:

(show top 50)    (show all 873)
idTitleAuthorsYear
1
Treatment of children and adolescents with idiopathic short stature. (23609338)
2013
2
Lactose intolerance: lack of evidence for short stature or vitamin d deficiency in prepubertal children. (24205288)
2013
3
Molecular study of a Hoxa2 gain-of-function in chondrogenesis: a model of idiopathic proportionate short stature. (24129174)
2013
4
SAMS, a syndrome of short stature, auditory-canal atresia, mandibular hypoplasia, and skeletal abnormalities is a unique neurocristopathy caused by mutations in Goosecoid. (24290375)
2013
5
Duplication of the Xq27.3-q28 region, including the FMR1 gene, in an X-linked hypogonadism, gynecomastia, intellectual disability, short stature, and obesity syndrome. (23897859)
2013
6
Profile and Height Outcomes of Children with Short Stature in North India: An Experience from a Tertiary Care Centre. (23616062)
2013
7
Severe lateral tibial bowing with short stature in two siblings--a provisionally novel syndrome. (22927185)
2012
8
Definition and subcategorization of idiopathic short stature: between consensus and controversy. (21912144)
2011
9
Indirect evidence for the genetic determination of short stature in African Pygmies. (21541921)
2011
10
Report of two brothers with short stature, microcephaly, mental retardation, and retinoschisis-A new mental retardation syndrome? (21204205)
2011
11
Identification and functional analysis of novel human growth hormone secretagogue receptor (GHSR) gene mutations in Japanese subjects with short stature. (21084395)
2011
12
A two year observation of the process of applying recombinant IGF-1 to treat short stature in children with primary IGF-1 deficiency -- case reports of 3 patients. (22248785)
2011
13
Chairman's summary: Therapeutic options for the treatment of children with idiopathic short stature. (21912154)
2011
14
Safety of growth hormone treatment of children with idiopathic short stature: the US experience. (21912165)
2011
15
Relationship between short stature and obesity in Brazil: a multilevel analysis. (20070916)
2010
16
Deletion of the CUL4B gene in a boy with mental retardation, minor facial anomalies, short stature, hypogonadism, and ataxia. (20014135)
2010
17
Variable degree of growth hormone (GH) and insulin-like growth factor (IGF) sensitivity in children with idiopathic short stature compared with GH-deficient patients: evidence from an IGF-based dosing study of short children. (20207829)
2010
18
The continuum of growth hormone-IGF-I axis defects causing short stature: diagnostic and therapeutic challenges. (20050859)
2010
19
A second patient with Tsukahara syndrome: type A1 brachydactyly, short stature, hearing loss, microcephaly, mental retardation and ptosis. (20358606)
2010
20
Evaluation of insulin-like growth factor-1 and insulinlike growth factor binding protein-3 in diagnosis of growth hormone deficiency in short-stature children. (20929010)
2009
21
Impact of aromatase inhibitor therapy on bone turnover, cortical bone growth and vertebral morphology in pre- and peripubertal boys with idiopathic short stature. (19339794)
2009
22
Clinical application of automated Greulich-Pyle bone age determination in children with short stature. (19333590)
2009
23
Dose-dependent effect of growth hormone on final height in children with short stature without growth hormone deficiency. (18728172)
2008
24
Short stature as a presenting feature of pheochromocytoma. (18279225)
2008
25
Statement 4: therapy should be offered to children with idiopathic short stature (ISS) whose heights are &lt; -2.25 standard deviation (SD) score. (18438328)
2008
26
Short stature, smoking habits and birth outcome in international adoptees in Sweden. (18972233)
2008
27
Age at growth hormone therapy start and first-year responsiveness to growth hormone are major determinants of height outcome in idiopathic short stature. (17228181)
2007
28
Four siblings with distal renal tubular acidosis and nephrocalcinosis, neurobehavioral impairment, short stature, and distinctive facial appearance: a possible new autosomal recessive syndrome. (17663471)
2007
29
Osteopoikilosis, short stature and mental retardation as key features of a new microdeletion syndrome on 12q14. (17220210)
2007
30
Osseous dysplasia with severe short stature, multiple dislocations, and delayed bone age: report on a second Lebanese patient. (17618475)
2007
31
Brachydactyly short-stature hypertension syndrome: a case with associated vascular malformations. (16369843)
2006
32
Genetic variants in the promoter region of the IGF-I gene as a reason for short stature. (16789640)
2006
33
Estimated cost-effectiveness of growth hormone therapy for idiopathic short stature. (16520445)
2006
34
Growth hormone use in children with idiopathic short stature. (15266039)
2004
35
Optic nerve size evaluated by magnetic resonance imaging in children with optic nerve hypoplasia, multiple pituitary hormone deficiency, isolated growth hormone deficiency, and idiopathic short stature. (15480381)
2004
36
A novel heterozygous T51I mutation of growth hormone receptor is not associated with short stature. (12423626)
2002
37
Cerebellar hypoplasia, hypergonadotrophic hypogonadism, retinitis pigmentosa, alopecia, microcephaly, psychomotor retardation, and short stature: &quot;D-CHRAMPS syndrome&quot;. (11998919)
2002
38
Poor reproducibility of IGF-I and IGF binding protein-3 generation test in children with short stature and normal coding region of the GH receptor gene. (11836270)
2002
39
Short stature in a mother and daughter caused by familial der(X)t(X;X)(p22.1-3;q26). (11471178)
2001
40
Short stature homeobox-containing gene duplication on the der(X) chromosome in a female with 45,X/46,X, der(X), gonadal dysgenesis, and tall stature. (10946905)
2000
41
Growth during and after a trial of growth hormone releasing hormone 1-29 in children with idiopathic short stature or growth hormone neurosecretory dysfunction. (10905389)
2000
42
A dominant-negative mutation of the growth hormone receptor causes familial short stature. (9140387)
1997
43
Diagnostic studies with intravenous and intranasal growth hormone-releasing peptide-2 in children of short stature. (7559885)
1995
44
Mutations of the growth hormone receptor in children with idiopathic short stature. (7565946)
1995
45
Reduced concentration of serum growth hormone-binding protein in children with idiopathic short stature. National Cooperative Growth Study. (8200933)
1994
46
The treatment with biosynthetic growth hormone (GH) of familial short stature]. (7935253)
1994
47
Mental retardation, congenital heart defect, cleft palate, short stature, and facial anomalies: a new X-linked multiple congenital anomalies/mental retardation syndrome: clinical description and molecular studies. (7943045)
1994
48
Postnatal short stature, microcephaly, severe syndactyly of hands and feet, dysmorphic face, and mental retardation: a new syndrome? (1316441)
1992
49
Partial isodisomy for maternal chromosome 7 and short stature in an individual with a mutation at the COL1A2 locus. (1463018)
1992
50
Autosomal recessive blepharophimosis, ptosis, V-esotropia, syndactyly and short stature. (1311991)
1992

Genetic Variations for Short Stature

Sources:
63UniProtKB/Swiss-Prot
See all sources

Genetic disease variations for Short Stature:

63
id Symbol AA change Variation SNP ID
1GHRp.Glu62LysVAR_002708
2GHRp.Arg179CysVAR_002714rs121909362
3GHSRp.Ala204GluVAR_032705

Expression for genes affiliated with Short Stature

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Short Stature

Search GEO for disease gene expression data for Short Stature.

Pathways for genes affiliated with Short Stature

Sources:
54Reactome, 30KEGG, 38NCBI BioSystems Database, 52QIAGEN, 12EMD Millipore
See all sources

Pathways related to Short Stature according to GeneCards/GeneDecks:

(show all 22)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
11.2GNRH1, GHRHR, GHR, GHSR, GHRL, GH1
2
Hide members
10.9GNRH1, GHRHR, GHR, GHSR, GHRL, GH1
3
Hide members
10.9GNRH1, GHR, GH1, IGF1R, IGF1, FGFR3
4
Translation Insulin regulation of translation
Hide members
10.9GHR, GH1, IGFBP3, IGF1R, IGF1, PTPN11
510.9ACAN, FGFR3, IGF1, IGF1R, GH1, GHR
6
Hide members
10.9GNRH1, GH1, IGF1R, IGF1, FGFR3, PTPN11
710.8GHR, GH1, IGF1R, IGF1, FGFR3
8
Hide members
10.8GNRH1, GH1, IGF1R, IGF1, FGFR3
9
Hide members
10.8GNRH1, GH1, IGF1R, IGF1, FGFR3
10
Hide members
10.8GNRH1, GH1, IGF1R, IGF1, FGFR3
11
Hide members
10.8GNRH1, GH1, IGF1R, IGF1, FGFR3
12
Hide members
10.8GHR, GH1, IGF1R, IGF1
13
Hide members
10.8PTPN11, FGFR3, GH1, GHR
14
Hide members
10.8GNRH1, GH1, IGF1, FGFR3
15
Hide members
10.8FGFR3, IGF1R, GH1, GNRH1
16
Hide members
10.7IGFBP1, IGFBP3, IGF1R, IGF1
17
Hide members
10.7PTPN11, FGFR3, IGF1, IGF1R
1810.7IGFBP1, GHSR, GHR
1910.7IGFBP1, IGFBP3, IGF1
2010.7IGF1, IGF1R, IGFBP3
21
Cell adhesion ECM remodeling
Hide members
10.7IGF1R, IGF1, ACAN
22
Hide members
10.6FGFR3, GH1

Compounds for genes affiliated with Short Stature

Sources:
45Novoseek, 60Tocris Bioscience, 29IUPHAR, 11DrugBank, 24HMDB, 50PharmGKB, 2BitterDB
See all sources

Compounds related to Short Stature according to GeneCards/GeneDecks:

(show top 50)    (show all 119)
idCompoundScoreTop Affiliating Genes
1arginine4511.7FGFR3, IGF1, IGFBP3, IGFBP1, GH1, GHRL
2ribonucleic acid4511.6IGF1, GHRHR, GNRH1, GHR, GHSR, GHRL
3octreotide45 60 29 1114.5IGF1, IGFBP3, IGFBP1, GH1, GHRL, GHSR
4estradiol45 11 2413.5GHR, GHSR, GHRL, GH1, IGFBP1, GNRH1
5testosterone45 60 11 2414.5GHR, GHSR, GH1, GHRL, GNRH1, IGFBP1
6steroid4511.5IGFBP1, GNRH1, GHR, SHOX, GHSR, GH1
7acth4511.5IGF1, IGFBP3, IGFBP1, GH1, GHRL, GHSR
8gnrh4511.4GNRH1, GH1, GHR, IGF1, GHRL, IGF1R
9vitamin d4511.4IGFBP1, IGF1R, IGFBP3, GHR, ACAN, IGF1
10hexarelin45 2912.4GHR, GHRHR, GHSR, GHRL, GH1, IGFBP3
11ghrp4511.4GHR, GHRHR, GHSR, GHRL, GH1, IGFBP3
12dexamethasone45 50 29 1114.4GHRHR, GHSR, GHRL, GH1, IGF1R, ACAN
13dehydroepiandrosterone sulfate4511.4IGF1, GNRH1, GHR, GHRL, GH1, IGFBP1
14c-peptide4511.4IGF1, GHR, GH1, IGFBP1, IGFBP3, IGF1R
15thymidine45 2412.4IGF1, PTPN11, IGF1R, GHRL, IGFBP3, IGFBP1
16dihydrotestosterone45 29 11 2414.4IGF1, IGFBP1, GH1, GHR, IGFBP3, GNRH1
17thyroxine45 2412.4GH1, IGFBP1, IGF1, IGFBP3, GNRH1, GHRL
18lanreotide45 2912.3GHR, GHSR, GH1, IGFBP1, IGFBP3, IGF1
19pegvisomant45 1112.3GH1, IGF1, IGFBP3, IGFBP1, GHRL, GHR
20clomiphene citrate4511.3IGFBP3, IGFBP1, IGF1R, IGF1, GNRH1, GH1
21tamoxifen45 50 29 1114.3IGF1R, IGF1, IGFBP1, GNRH1, GHR, IGFBP3
22triiodothyronine4511.3GHR, GHRL, GH1, IGFBP3, IGF1, IGFBP1
23creatinine4511.3IGF1, IGF1R, IGFBP3, IGFBP1, GHRL, GHR
24androstenedione45 2412.3GNRH1, GHR, GH1, IGFBP1, IGFBP3, IGF1
25retinoic acid45 2412.2IGFBP3, IGF1R, IGF1, IGFBP1, ACAN, GH1
26pyridostigmine45 1112.2GH1, IGFBP1, IGFBP3, IGF1, GHRL
27cabergoline29 45 1113.2GNRH1, IGF1, IGFBP3, GHR, GH1
28oxandrolone45 1112.1IGF1, IGFBP3, GH1, GHRL
29metformin45 50 1113.1IGF1, IGFBP1, GH1, GHRL, GNRH1
30calcitriol45 60 11 2414.1IGFBP3, IGF1, IGFBP1, GH1, GHR, IGF1R
31serine4511.1CTSK, GHRL, GH1, FGFR3, PTPN11
32glucose4511.1IGF1R, IGF1, GHRL, IGFBP3
33raloxifene45 29 50 1114.1GNRH1, GH1, IGF1, IGF1R
34dhea4511.1IGFBP1, IGFBP3, IGF1, GH1, GHRL
35buserelin45 29 1113.1IGFBP3, IGF1, IGFBP1, GNRH1
36leuprolide acetate4511.1GHR, GNRH1, GH1, IGF1
37glutamate4511.1GHRHR, GHRL, GNRH1
38bromocriptine29 45 1113.0IGFBP3, GNRH1, GHR
39pirenzepine45 29 1113.0IGFBP1, IGF1, GH1, GHRL
40naltrexone45 50 29 1114.0IGF1, GNRH1, GH1, IGFBP3
41cysteine4511.0CTSK, GHRHR, IGFBP1, IGF1R, FGFR3, PTPN11
42progestin4511.0IGF1, IGFBP3, GNRH1, IGFBP1, IGF1R
43estrogen4510.9SHOX
44forskolin45 50 1112.9PTPN11, GHSR, GHRHR
45hydrocortisone45 2 60 1113.8IGFBP1, GH1, GHRL, GHSR, IGF1
46estrone45 29 11 2413.8IGF1, GNRH1, GH1, IGFBP1, IGFBP3
47deoxypyridinoline4510.8GH1, IGF1, IGFBP3, IGFBP1
48procollagen4510.8ACAN
49vegf4510.7IGF1R, PTPN11, GH1, IGFBP3, IGFBP1, GHRL
50mecasermin45 1111.6IGF1, IGF1R, IGFBP3

GO Terms for genes affiliated with Short Stature

Sources:
16Gene Ontology
See all sources

Cellular components related to Short Stature according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:00557611.1ACAN, GNRH1, CTSK, GHR, GHRL, GH1
2extracellular spaceGO:00561510.7GNRH1, CTSK, GHR, GHRL, GH1, IGFBP1
3insulin-like growth factor binding protein complexGO:01694210.6IGF1, IGFBP3

Biological processes related to Short Stature according to GeneCards/GeneDecks:

(show all 32)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of insulin-like growth factor receptor signaling pathwayGO:04356811.2IGF1, IGFBP3, GH1, GHSR, GHRHR
2positive regulation of multicellular organism growthGO:04001811.2GHRHR, GHR, GHSR, GHRL, GH1
3skeletal system developmentGO:00150111.2SHOX, SHOX2, IGF1, FGFR3, ACAN
4hormone-mediated signaling pathwayGO:00975511.1GHR, GHSR, GHRL, PTPN11
5positive regulation of MAPK cascadeGO:04341011.1IGFBP3, IGF1R, IGF1, FGFR3
6phosphatidylinositol-mediated signalingGO:04801511.1PTPN11, FGFR3, IGF1, IGF1R
7growth hormone secretionGO:03025211.1GHRL, GHSR, GHRHR
8insulin-like growth factor receptor signaling pathwayGO:04800911.1IGF1, IGF1R, GHR
9positive regulation of tyrosine phosphorylation of Stat5 proteinGO:04252311.1IGF1, GH1, GHR
10insulin receptor signaling pathwayGO:00828611.0IGFBP1, IGF1R, FGFR3, PTPN11
11negative regulation of insulin secretionGO:04667611.0GHSR, GHRL, PTPN11
12regulation of multicellular organism growthGO:04001411.0GHR, IGF1, PTPN11
13JAK-STAT cascadeGO:00725911.0GHR, GH1, FGFR3
14positive regulation of tyrosine phosphorylation of Stat3 proteinGO:04251711.0FGFR3, GH1, GHR
15cellular response to insulin stimulusGO:03286911.0GHRHR, GHR, GHSR
16bone maturationGO:07097711.0GH1, FGFR3
17multicellular organismal reproductive processGO:04860910.9GHRHR, PTPN11
18positive regulation of appetiteGO:03210010.9GHSR, GHRL
19positive regulation of peptidyl-tyrosine phosphorylationGO:05073110.9IGF1, GH1, GHR
20water homeostasisGO:03010410.9IGF1, GHRHR
21negative regulation of tumor necrosis factor biosynthetic processGO:04253610.9GHRL, GHSR
22negative regulation of interleukin-6 biosynthetic processGO:04540910.9GHRL, GHSR
23negative regulation of interleukin-1 beta productionGO:03269110.9GHSR, GHRL
24growth hormone receptor signaling pathwayGO:06039610.8GHR, GH1
25cartilage development involved in endochondral bone morphogenesisGO:06035110.8GHR, SHOX2
26positive regulation of growth hormone secretionGO:06012410.8GHRHR, GHRL
27exocrine pancreas developmentGO:03101710.7IGF1R, IGF1
28response to foodGO:03209410.7GHSR, GHR
29adult feeding behaviorGO:00834310.6GHSR, GHRL
30hormone metabolic processGO:04244510.6PTPN11, GHRHR
31actin polymerization or depolymerizationGO:00815410.5GHRL, GHSR
32activation of MAPK activityGO:00018710.4PTPN11, GHRL, GHR

Molecular functions related to Short Stature according to GeneCards/GeneDecks:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1insulin-like growth factor bindingGO:00552010.8IGF1R, IGFBP3, IGFBP1
2peptide hormone bindingGO:01704610.8GHRHR, GHR, GHSR
3insulin receptor bindingGO:00515810.7PTPN11, IGF1, IGF1R
4growth hormone-releasing hormone receptor activityGO:01652010.6GHRHR, GHSR
5insulin receptor substrate bindingGO:04356010.6PTPN11, IGF1R
6insulin-like growth factor I bindingGO:03199410.5IGF1R, IGFBP3
7hormone activityGO:00517910.4IGF1, GH1, GNRH1

Products for genes affiliated with Short Stature

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Short Stature

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet