Shox-related Haploinsufficiency Disorders malady

MalaCards: Shox-related Haploinsufficiency Disorders, also known as haploinsufficiency, is related to leukemia and short stature. An important gene associated with Shox-related Haploinsufficiency Disorders is SHOX (short stature homeobox).

GeneReviews summary for lwd

shox-related haploinsufficiency disorders 15 16 haploinsufficiency 43

Diseases related to shox-related haploinsufficiency disorders by text searches and GeneDecks gene sharing:

(show top 50)    (show all 120)

id	Related Disease	Score	Top Affiliating Genes
1	leukemia	7.3
2	short stature	6.9
3	cardiomyopathy	6.4
4	neurofibromatosis	6.0
5	prostatitis	6.0
6	saethre-chotzen syndrome	6.0
7	williams-beuren syndrome	6.0
8	waardenburg's syndrome	6.0
9	waardenburg syndrome type 2	6.0
10	chondrodysplasia	6.0
11	dyskeratosis congenita	6.0
12	dyskeratosis	6.0
13	ehlers-danlos syndrome	6.0
14	hypertrophic cardiomyopathy	6.0
15	keratoderma	5.5
16	schmid metaphyseal chondrodysplasia	5.5
17	leri-weill dyschondrosteosis	5.5
18	smith-magenis syndrome	5.5
19	lymphedema	5.5
20	supravalvular aortic stenosis	5.5
21	lymphoblastic leukemia	5.5
22	sotos syndrome	5.5
23	lymphedema-distichiasis syndrome	5.5
24	medulloblastoma	5.5
25	turner syndrome	5.5
26	marfan syndrome	5.5
27	waardenburg syndrome type 2a	5.5
28	acute myeloid leukemia	5.5
29	metaphyseal chondrodysplasia	5.5
30	acute lymphoblastic leukemia	5.5
31	myeloid leukemia	5.5
32	anemia	5.5
33	myopathy	5.5
34	osteochondroma	5.5
35	pfeiffer syndrome	5.5
36	fibrosis	5.5
37	polyposis	5.5
38	holoprosencephaly	5.5
39	pancreatitis	5.5
40	infertility	5.5
41	prostate cancer	5.5
42	angioedema	4.6
43	carney complex	4.6
44	lymphoproliferative syndrome	4.6
45	peters anomaly	4.6
46	williams syndrome	4.6
47	aplastic anemia	4.6
48	corticosteroid-binding globulin deficiency	4.6
49	hereditary angioedema	4.6
50	rhabdomyosarcoma	4.6

Approved drugs:

Drug clinical trials:

Genetic tests related to shox-related haploinsufficiency disorders:

id	Genetic test	Affiliating Genes
1	Shox-related Haploinsufficiency Disorders clinical/research	SHOX

Genes related to shox-related haploinsufficiency disorders according to GeneCards:

id	Symbol	Description	Score	GeneCards Section Context
1	SHOX	short stature homeobox	11.1	Disorders