MCID: SLL001
MIFTS: 43

Sialolithiasis malady

Categories: Gastrointestinal diseases, Oral diseases, Endocrine diseases

Aliases & Classifications for Sialolithiasis

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Aliases & Descriptions for Sialolithiasis:

Name: Sialolithiasis 10 12 65
Stone of Salivary Gland or Duct 10
Salivary Gland Calculi 36
 
Salivary Gland Stone 10
Sialolithiasis Nos 10
Sialolith 10

Classifications:



External Ids:

Disease Ontology10 DOID:12905
ICD1027 K11.5
ICD9CM29 527.5
MeSH36 D015494
NCIt42 C34994
UMLS65 C0036091

Summaries for Sialolithiasis

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Wikipedia:68 Sialolithiasis (also termed salivary calculi, or salivary stones), is a condition where a calcified mass... more...

MalaCards based summary: Sialolithiasis, also known as stone of salivary gland or duct, is related to best1 retinopathy and non-distal monosomy 10q, and has symptoms including sialectasia nosand salivary gland pain. An important gene associated with Sialolithiasis is ACBD6 (Acyl-CoA Binding Domain Containing 6), and among its related pathways are Downstream signaling in naive CD8+ T cells and IL12-mediated signaling events. Affiliated tissues include salivary gland, lung and b cells, and related mouse phenotypes are normal and endocrine/exocrine gland.

Related Diseases for Sialolithiasis

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Diseases related to Sialolithiasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 54)
idRelated DiseaseScoreTop Affiliating Genes
1best1 retinopathy10.7HLA-DPB1, HLA-DQB1
2non-distal monosomy 10q10.7HLA-DPB1, HLA-DQB1
3subcorneal pustular dermatosis10.6HLA-DPB1, HLA-DQB1
4dental pulp calcification10.6FASLG, GZMB
5pineal region choriocarcinoma10.5FASLG, GZMB
6somatoform disorder10.5ALB, CASR
7sialolithiasis10.5ITGA2, NOTCH1
8necrotizing gastritis10.5CD8A, GZMB
9ocular muscular dystrophy10.4CTGF, HLA-DQB1
10monkeypox10.4CD38, CD8A
11episodic ataxia10.4ALB, CTGF
12subacute glomerulonephritis10.3ALB, CFP, FASLG
13ossifying fibroma10.3ALB, CTGF, HAVCR1
14autoimmune disease of musculoskeletal system10.3CD8A, HLA-DPB1, HLA-DQB1
15indolent myeloma10.2ALB, CD38
16spondyloarthropathy 110.2CD8A, FASLG, GZMB
17ulcerative stomatitis10.2ALB, CD8A
18sialadenitis10.2
19benign shuddering attacks10.1CD38, NOTCH1
20myositis ossificans10.1CD38, CD8A
21sarcoidosis 110.0GZMB, HLA-DPB1, HLA-DQB1
22psychotic disorder10.0ALB, CTGF, HBA1
23cell type cancer9.9ALB, CD8A, NOTCH1
24hemangioma9.9
25gastrointestinal tuberculosis9.9NOTCH1, PRTN3
26q fever9.8FASLG, NOTCH1
27tenosynovitis of foot and ankle9.8ALB, CD8A, ZNF135
28cystic fibrosis9.7
29multiple myeloma9.7
30nephrolithiasis9.7
31adenoiditis9.7
32myeloma9.7
33cholelithiasis9.7
34salivary gland disease9.7
35primary hyperparathyroidism9.7
36hyperparathyroidism9.7
37down syndrome9.7
38cervicitis9.7
39epidermolysis bullosa9.7
40cavernous hemangioma9.7
41pancreatitis9.7
42acquired immunodeficiency syndrome9.7
43periodontitis9.7
44actinomycosis9.7
45neuropathy9.7
46odontoma9.7
47vascular malformation9.7
48chronic pain9.7
49dysphagia9.7
50glycogen storage disease9.7ALB, CFP, PRTN3

Comorbidity relations with Sialolithiasis via Phenotypic Disease Network (PDN):


Hypertension, EssentialSialadenitis

Graphical network of the top 20 diseases related to Sialolithiasis:



Diseases related to sialolithiasis

Symptoms for Sialolithiasis

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UMLS symptoms related to Sialolithiasis:


sialectasia nos, salivary gland pain

Drugs & Therapeutics for Sialolithiasis

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Sialolithiasis


Cochrane evidence based reviews: salivary gland calculi

Genetic Tests for Sialolithiasis

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Anatomical Context for Sialolithiasis

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MalaCards organs/tissues related to Sialolithiasis:

33
Salivary gland, Lung, B cells, Pituitary, Heart, Breast, Myeloid

Animal Models for Sialolithiasis or affiliated genes

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MGI Mouse Phenotypes related to Sialolithiasis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00028738.2ALB, CD8A, CFP, CTGF, FASLG, HLA-DQB1
2MP:00053797.9ALB, CASR, CD38, CD8A, FASLG, HLA-DQB1
3MP:00053847.0ALB, CASR, CD38, CTGF, FASLG, HLA-DQB1
4MP:00053976.9CASR, CD38, CD8A, FASLG, HLA-DQB1, ITGA2
5MP:00053766.8ALB, CASR, CD38, CFP, CTGF, FASLG
6MP:00053876.7CASR, CD38, CD8A, CFP, FASLG, HLA-DQB1

Publications for Sialolithiasis

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Articles related to Sialolithiasis:

(show top 50)    (show all 238)
idTitleAuthorsYear
1
Sialolithiasis in horses: A retrospective study of 25 cases (2002-2013). (26663918)
2015
2
Endoscopic-assisted gland preserving therapy for the management of parotid gland sialolithiasis: Our preliminary experience. (26293189)
2015
3
Sialolithiasis: Use tomosynthesis! (25523323)
2015
4
Salivary gland diseases: infections, sialolithiasis and mucoceles. (24862601)
2014
5
Foreign body induced sialolithiasis treated by sialoendoscopic intervention. (25006917)
2014
6
Sialolithiasis. Proposal for a new minimally invasive procedure: Piezoelectric surgery. (25136434)
2014
7
Reliability of sonography in the assessment of sialolithiasis: is the fishnet mesh too small? (24370156)
2014
8
What is your diagnosis? Mandibular sialolithiasis. (24548226)
2014
9
An aberrant parotid gland duct with a cutaneous orifice, accompanied by sialolithiasis. (22901859)
2013
10
Sialolithiasis in a 10 year old child. (23257494)
2012
11
Etiologic factors in sialolithiasis. (21753035)
2011
12
Complication of adenoid cystic carcinoma and sialolithiasis in the submandibular gland: report of a case and its etiological background. (21159490)
2011
13
Increased calcium and decreased magnesium and citrate concentrations of submandibular/sublingual saliva in sialolithiasis. (19962126)
2010
14
Pathogenesis and diverse histologic findings of sialolithiasis in minor salivary glands. (20116725)
2010
15
In reference to Lithotripsy for refractory pediatric sialolithiasis (Laryngoscope 2009;119:298-299). (19688849)
2009
16
Sialolithiasis of the submandibular salivary gland treated with the 810- to 830-nm diode laser. (19099383)
2008
17
Sublingual salivary gland sialolithiasis in a dog. (18373538)
2008
18
Tonsilloliths associated with sialolithiasis in the submandibular gland. (18201626)
2008
19
Parotid duct sialolithiasis in a dog. (17209085)
2007
20
First case of sialolithiasis associated with atomoxetine. (17224735)
2007
21
Submandibular duct sialolithiasis : an unusual presentation. (17007760)
2006
22
An unusual case of bilateral submandibular sialolithiasis in a young female patient. (15850690)
2005
23
Sialolithiasis of submandibular gland. (14980352)
2004
24
Characterization of lymphoid infiltrates in chronic obstructive sialadenitis associated with sialolithiasis. (15078491)
2004
25
Endoscopic management of submandibular sialolithiasis. (12618947)
2003
26
Sialolithiasis: an unusually large submandibular salivary stone. (12199129)
2002
27
Histopathology of submandibular glands removed for sialolithiasis. (11372932)
2001
28
Pediatric sialolithiasis. (11113815)
2000
29
Symptomatic sialoadenitis and sialolithiasis in the English population, an estimate of the cost of hospital treatment. (10365495)
1999
30
The management of sialolithiasis in 2 children through use of extracorporeal shock wave lithotripsy. (10442944)
1999
31
Laser lithotripsy: a preliminary study on its application for sialolithiasis. (7947565)
1994
32
Angiolithiasis and sialolithiasis in the head and neck. (1570941)
1992
33
An uncommon case of parotid sialolithiasis. (1872587)
1991
34
Submandibular sialolithiasis: transoral excision. (2593220)
1989
35
Effects of experimentally-induced sialolithiasis on the composition of rat submandibular saliva. (3465945)
1986
36
Submandibular sialolithiasis in children. (6955470)
1982
37
Sialolithiasis: the radiolucent ones. (1059067)
1975
38
Sialolithiasis and sialoadenitis of a minor salivary gland: report of case. (4503105)
1972
39
Sialolithiasis of accessory salivary glands: review of 55 cases. (4507238)
1972
40
Sialolithiasis of a minor salivary gland. A case report and review of the literature. (5264862)
1970
41
Sialolithiasis and enlarged genial tubercles. (5272046)
1970
42
Sialolithiasis of the minor salivary glands: report of three cases. (5238931)
1968
43
Sialolithiasis--diagnosis and treatment. (5237062)
1967
44
MINOR SALIVARY GLAND SIALOLITHIASIS. REPORT OF A CASE. (14117364)
1964
45
Sialographic studies on submandibular sialolithiasis. (13946669)
1963
46
Sialolithiasis of a minor salivary gland. (13809470)
1960
47
Studies in sialolithiasis. I. The structure and mineralogical composition of salivary gland calculi. (13583890)
1958
48
Studies in sialolithiasis. II. Uric acid calculus of the parotid gland; report of a case. (13606697)
1958
49
Sialolithiasis, Wharton's duct, left submaxillary gland; report of a case. (13297388)
1956
50
Sialolithiasis. (18873404)
1948

Variations for Sialolithiasis

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Expression for genes affiliated with Sialolithiasis

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Search GEO for disease gene expression data for Sialolithiasis.

Pathways for genes affiliated with Sialolithiasis

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GO Terms for genes affiliated with Sialolithiasis

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Cellular components related to Sialolithiasis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1MHC class II protein complexGO:004261310.1HLA-DPB1, HLA-DQB1
2integral component of lumenal side of endoplasmic reticulum membraneGO:007155610.0HLA-DPB1, HLA-DQB1

Biological processes related to Sialolithiasis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1antigen processing and presentationGO:001988210.3HLA-DPB1, HLA-DQB1
2response to organic cyclic compoundGO:00140709.6CASR, CTGF, ITGA2
3branching morphogenesis of an epithelial tubeGO:00487549.5CASR, NOTCH1

Sources for Sialolithiasis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet