MCID: SLL001
MIFTS: 29

Sialolithiasis malady

Categories: Gastrointestinal diseases, Oral diseases, Endocrine diseases

Aliases & Classifications for Sialolithiasis

Aliases & Descriptions for Sialolithiasis:

Name: Sialolithiasis 12 14 69
Stone of Salivary Gland or Duct 12
Salivary Gland Calculi 42
Salivary Gland Stone 12
Sialolith 12

Classifications:



External Ids:

Disease Ontology 12 DOID:12905
ICD10 33 K11.5
ICD9CM 35 527.5
MeSH 42 D015494
NCIt 47 C34994
UMLS 69 C0036091

Summaries for Sialolithiasis

MalaCards based summary : Sialolithiasis, also known as stone of salivary gland or duct, is related to sialadenitis and hypertension, essential. An important gene associated with Sialolithiasis is TRPC3 (Transient Receptor Potential Cation Channel Subfamily C Member 3), and among its related pathways/superpathways are Ion channel transport and Platelet homeostasis. Affiliated tissues include salivary gland.

Wikipedia : 71 Sialolithiasis (also termed salivary calculi, or salivary stones), is a condition where a calcified mass... more...

Related Diseases for Sialolithiasis

Diseases related to Sialolithiasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 25)
id Related Disease Score Top Affiliating Genes
1 sialadenitis 10.1
2 hypertension, essential 10.0 TRPC3 XK
3 angiokeratoma 9.8 CFP XK
4 hemangioma 9.8
5 odontoma 9.6
6 nephrolithiasis 9.6
7 vascular malformation 9.6
8 adenoiditis 9.6
9 chronic pain 9.6
10 cholelithiasis 9.6
11 dysphagia 9.6
12 salivary gland disease 9.6
13 hyperparathyroidism 9.6
14 down syndrome 9.6
15 cervicitis 9.6
16 epidermolysis bullosa 9.6
17 cavernous hemangioma 9.6
18 pancreatitis 9.6
19 acquired immunodeficiency syndrome 9.6
20 periodontitis 9.6
21 cystic fibrosis 9.6
22 actinomycosis 9.6
23 multiple myeloma 9.6
24 neuropathy 9.6
25 screw worm infectious disease 9.2 ATP2B3 CFP HAVCR1 TRPC3 XK

Comorbidity relations with Sialolithiasis via Phenotypic Disease Network (PDN):


Hypertension, Essential Sialadenitis

Graphical network of the top 20 diseases related to Sialolithiasis:



Diseases related to Sialolithiasis

Symptoms & Phenotypes for Sialolithiasis

Drugs & Therapeutics for Sialolithiasis

Interventional clinical trials:


id Name Status NCT ID Phase
1 The Association Between Nephrolithiasis and Periodontal Status Not yet recruiting NCT03102086

Search NIH Clinical Center for Sialolithiasis

Cochrane evidence based reviews: salivary gland calculi

Genetic Tests for Sialolithiasis

Anatomical Context for Sialolithiasis

MalaCards organs/tissues related to Sialolithiasis:

39
Salivary Gland

Publications for Sialolithiasis

Articles related to Sialolithiasis:

(show top 50) (show all 248)
id Title Authors Year
1
Transoral submandibulotomy for deep hilar submandibular gland sialolithiasis. ( 28052363 )
2017
2
Rapid recurrent sialolithiasis: Altered stone composition and potential factors for recurrence. ( 27753112 )
2016
3
Sialendoscopy for Sublingual Gland Sialolithiasis. ( 28056531 )
2016
4
Possible Drug-Associated Sialolithiasis From the Bicarbonate Anhydrase Inhibitor Topiramate: A Case Report and Literature Review. ( 27292524 )
2016
5
Sialolithiasis is associated with nephrolithiasis: a case-control study. ( 26808906 )
2016
6
Parotid cyst due to sialolithiasis masquerading as pilomatrixoma on FNA. ( 27943427 )
2016
7
Sialolithiasis in an Accessory Submandibular Gland Identified by Magnetic Resonance Sialography. ( 26961009 )
2016
8
A Hard Calculus: Submandibular Sialolithiasis. ( 27742262 )
2016
9
A Case of Sialolithiasis in a Minor Salivary Gland of the Buccal Mucosa. ( 28050512 )
2016
10
Sialadenitis without sialolithiasis: Prospective outcomes after sialendoscopy-assisted salivary duct surgery. ( 27701754 )
2016
11
A population-based study on the association between chronic periodontitis and sialolithiasis. ( 26808379 )
2016
12
Recurrent sialoliths after excision of the bilateral submandibular glands for sialolithiasis treatment: A case report. ( 26889264 )
2016
13
Incidence of sialolithiasis in Denmark: a nationwide population-based register study. ( 28005152 )
2016
14
Canine Sialolithiasis: Two Case Reports with Breed, Gender, and Age Distribution of 29 Cases (1964-2010). ( 26606211 )
2016
15
Does saliva composition affect the formation of sialolithiasis? ( 27974066 )
2016
16
Does drinking water influence hospital-admitted sialolithiasis on an epidemiological level in Denmark? ( 25941183 )
2015
17
Clinicopathological aspects of 25 cases of sialolithiasis of minor salivary glands. ( 25945774 )
2015
18
Sialolithiasis in horses: A retrospective study of 25 cases (2002-2013). ( 26663918 )
2015
19
Unusual form of sialolithiasis: case report with 3-dimensional imaging. ( 26530733 )
2015
20
Endoscopic-assisted gland preserving therapy for the management of parotid gland sialolithiasis: Our preliminary experience. ( 26293189 )
2015
21
Sialolithiasis of an accessory parotid gland: an unusual case. ( 26048098 )
2015
22
Sialolithiasis: Use tomosynthesis! ( 25523323 )
2015
23
Combined approach sialendoscopy for management of submandibular gland sialolithiasis. ( 26052045 )
2015
24
Sialadenitis Without Sialolithiasis Treated by Sialendoscopy. ( 25863231 )
2015
25
Foreign body induced sialolithiasis treated by sialoendoscopic intervention. ( 25006917 )
2014
26
Bedside emergency ultrasound in a case of acute parotid duct sialolithiasis. ( 24877763 )
2014
27
Sialolithiasis. Proposal for a new minimally invasive procedure: Piezoelectric surgery. ( 25136434 )
2014
28
Multiple bilateral submandibular gland sialolithiasis. ( 24326820 )
2014
29
What is your diagnosis? Mandibular sialolithiasis. ( 24548226 )
2014
30
The Association of Sialolithiasis with Cholelithiasis: A Population-Based Study. ( 25482495 )
2014
31
Submandibular hemangioma with multiple phleboliths mimicking sialolithiasis: the first pediatric case. ( 25010807 )
2014
32
Zygomatic sialolithiasis diagnosed with computed tomography in a dog. ( 24942114 )
2014
33
Objective and subjective outcome in 42 patients after treatment of sialolithiasis by transoral incision of Warthon's duct: a retrospective middle-term follow-up study. ( 24493562 )
2014
34
Learning Progression in the Use of Sialendoscopy for Sialolithiasis: Effect on Gland Preservation. ( 24812078 )
2014
35
Minimally invasive surgery of sialolithiasis using sialendoscopy. ( 24970706 )
2014
36
Outcomes of Holmium Laser-Assisted Lithotripsy with Sialendoscopy in Treatment of Sialolithiasis. ( 24598407 )
2014
37
Reliability of sonography in the assessment of sialolithiasis: is the fishnet mesh too small? ( 24370156 )
2014
38
Long-term results of combined approach in parotid sialolithiasis. ( 25388993 )
2014
39
Submandibular venous malformation phleboliths mimicking sialolithiasis in children. ( 24986521 )
2014
40
Scintigraphic detection of a parotid salivary gland malfunction, in chronic sialolithiasis and fat infiltration with no risk factors. ( 24563881 )
2014
41
Salivary gland diseases: infections, sialolithiasis and mucoceles. ( 24862601 )
2014
42
Comparative analysis of sialendoscopy, sonography, and CBCT in the detection of sialolithiasis. ( 25345873 )
2014
43
Algorithm changes in treatment of submandibular gland sialolithiasis. ( 23568038 )
2013
44
An aberrant parotid gland duct with a cutaneous orifice, accompanied by sialolithiasis. ( 22901859 )
2013
45
Submandibular sialolithiasis in a child. ( 23378557 )
2013
46
Deep and unusual sialolithiasis of submandibular duct and gland: a surgical dilemma. ( 24427589 )
2013
47
Ho:Yag laser for sialolithiasis of Wharton's duct. ( 23462654 )
2013
48
Submandibular sialolithiasis: Report of six cases. ( 24082702 )
2013
49
Minor salivary gland sialolithiasis of the upper lip. ( 24371404 )
2013
50
Combined endoscopic-transcutaneous surgery in parotid gland sialolithiasis and other ductal diseases: reporting medium- to long-term objective and patients' subjective outcomes. ( 23224766 )
2013

Variations for Sialolithiasis

Expression for Sialolithiasis

Search GEO for disease gene expression data for Sialolithiasis.

Pathways for Sialolithiasis

Pathways related to Sialolithiasis according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1
Show member pathways
11.45 ATP2B3 TRPC3
2
Show member pathways
10.9 ATP2B3 TRPC3

GO Terms for Sialolithiasis

Biological processes related to Sialolithiasis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 calcium ion transport GO:0006816 9.16 ATP2B3 TRPC3
2 calcium ion transmembrane transport GO:0070588 8.96 ATP2B3 TRPC3
3 cellular calcium ion homeostasis GO:0006874 8.62 ATP2B3 XK

Sources for Sialolithiasis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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