MCID: SLL001
MIFTS: 39

Sialolithiasis malady

Categories: Gastrointestinal diseases, Oral diseases, Endocrine diseases

Aliases & Classifications for Sialolithiasis

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Aliases & Descriptions for Sialolithiasis:

Name: Sialolithiasis 11 13 66
Stone of Salivary Gland or Duct 11
Salivary Gland Calculi 37
 
Salivary Gland Stone 11
Sialolithiasis Nos 11
Sialolith 11

Classifications:



External Ids:

Disease Ontology11 DOID:12905
ICD1028 K11.5
ICD9CM30 527.5
MeSH37 D015494
NCIt43 C34994

Summaries for Sialolithiasis

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Wikipedia:69 Sialolithiasis (also termed salivary calculi, or salivary stones), is a condition where a calcified mass... more...

MalaCards based summary: Sialolithiasis, also known as stone of salivary gland or duct, is related to trigeminal nerve disease and granulomatous gastritis, and has symptoms including salivary gland pain and sialectasia nos. An important gene associated with Sialolithiasis is TRPC3 (Transient Receptor Potential Cation Channel Subfamily C Member 3), and among its related pathways are Transcription_Role of VDR in regulation of genes involved in osteoporosis and IL12-mediated signaling events. Affiliated tissues include salivary gland, and related mouse phenotypes are integument and endocrine/exocrine gland.

Related Diseases for Sialolithiasis

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Diseases related to Sialolithiasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 49)
idRelated DiseaseScoreTop Affiliating Genes
1trigeminal nerve disease10.5FASLG, GZMB
2granulomatous gastritis10.5FASLG, GZMB
3plasmodium ovale malaria10.4ITGA2, NOTCH1
4chronic progressive external ophthalmoplegia10.3ALB, HAVCR1, XK
5testicular brenner tumor10.3ALB, CASR
6mixed hepatoblastoma10.3NOTCH1, SPP1
7mesangial proliferative glomerulonephritis10.3ALB, CFP, FASLG
8subvalvular aortic stenosis10.2HAVCR1, MGAM, XK
9astrakhan spotted fever10.2CASR, MGAM, XK
10sialadenitis10.2
11vaccinia10.2CD38, CD8A
12stomatitis10.1ALB, CTGF
13breast mucoepidermoid carcinoma10.1ALB, CASR, SPP1
14intestinal disaccharidase deficiency10.1ALB, CD8A
15spondyloarthropathy 110.1CD8A, FASLG, GZMB
16white platelet syndrome10.0CD38, NOTCH1
17perianal skin paget's disease10.0ALB, CD8A, XK
18testicular malignant germ cell cancer10.0FASLG, GZMB
19angiomyolipoma9.9ALB, CD8A, XK
20hemangioma9.9
21taylor's syndrome9.9ALB, CD38, CD8A
22chronic intestinal vascular insufficiency9.8ALB, CD8A, XK
23cystic fibrosis9.7
24multiple myeloma9.7
25nephrolithiasis9.7
26adenoiditis9.7
27myeloma9.7
28cholelithiasis9.7
29salivary gland disease9.7
30primary hyperparathyroidism9.7
31hyperparathyroidism9.7
32down syndrome9.7
33cervicitis9.7
34epidermolysis bullosa9.7
35cavernous hemangioma9.7
36pancreatitis9.7
37acquired immunodeficiency syndrome9.7
38periodontitis9.7
39actinomycosis9.7
40neuropathy9.7
41odontoma9.7
42vascular malformation9.7
43chronic pain9.7
44dysphagia9.7
45gemistocytic astrocytoma9.6ALB, CD8A, XK
46skeletal muscle cancer9.6NOTCH1, PRTN3, SPP1
47brachyolmia9.6ALB, CD8A, NOTCH1
48mononeuritis9.3ALB, CTGF, HAVCR1, PRTN3, XK
49hypodermyiasis4.4ALB, ATP2B3, CASR, CD38, CD8A, CFP

Comorbidity relations with Sialolithiasis via Phenotypic Disease Network (PDN):


Hypertension, EssentialSialadenitis

Graphical network of the top 20 diseases related to Sialolithiasis:



Diseases related to sialolithiasis

Symptoms for Sialolithiasis

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UMLS symptoms related to Sialolithiasis:


salivary gland pain, sialectasia nos

Drugs & Therapeutics for Sialolithiasis

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Sialolithiasis


Cochrane evidence based reviews: salivary gland calculi

Genetic Tests for Sialolithiasis

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Anatomical Context for Sialolithiasis

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MalaCards organs/tissues related to Sialolithiasis:

34
Salivary gland

Animal Models for Sialolithiasis or affiliated genes

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MGI Mouse Phenotypes related to Sialolithiasis:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00107718.2CASR, CD8A, CTGF, FASLG, ITGA2, NOTCH1
2MP:00053797.1ALB, CASR, CD38, CD8A, FASLG, ITGA2
3MP:00028737.0ALB, CD8A, CFP, CTGF, FASLG, ITGA2
4MP:00053876.8CASR, CD38, CD8A, CFP, FASLG, LRP5
5MP:00053846.6ALB, CASR, CD38, CTGF, FASLG, ITGA2
6MP:00053976.3CASR, CD38, CD8A, FASLG, ITGA2, LRP5
7MP:00053766.3ALB, CASR, CD38, CFP, CTGF, FASLG

Publications for Sialolithiasis

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Articles related to Sialolithiasis:

(show top 50)    (show all 239)
idTitleAuthorsYear
1
Sialolithiasis in an Accessory Submandibular Gland Identified by Magnetic Resonance Sialography. (26961009)
2016
2
Possible Drug-Associated Sialolithiasis From the Bicarbonate Anhydrase Inhibitor Topiramate: A Case Report and Literature Review. (27292524)
2016
3
Sialolithiasis in horses: A retrospective study of 25 cases (2002-2013). (26663918)
2015
4
Sialolithiasis of an accessory parotid gland: an unusual case. (26048098)
2015
5
Reliability of sonography in the assessment of sialolithiasis: is the fishnet mesh too small? (24370156)
2014
6
What is your diagnosis? Mandibular sialolithiasis. (24548226)
2014
7
Submandibular sialolithiasis in a child. (23378557)
2013
8
Ho:Yag laser for sialolithiasis of Wharton's duct. (23462654)
2013
9
Submandibular sialolithiasis: Report of six cases. (24082702)
2013
10
Algorithm changes in treatment of submandibular gland sialolithiasis. (23568038)
2013
11
Contrast-enhanced ultrasound for monitoring effects of extracorporeal shock wave sialolithotripsy in sialolithiasis. (22522958)
2012
12
Etiologic factors in sialolithiasis. (21753035)
2011
13
Sialolithiasis of the submandibular gland. (21586966)
2011
14
A rare case of sialolithiasis of the lower lip simulating a mucocele and review of the literature. (21716987)
2011
15
Increased calcium and decreased magnesium and citrate concentrations of submandibular/sublingual saliva in sialolithiasis. (19962126)
2010
16
Pathogenesis and diverse histologic findings of sialolithiasis in minor salivary glands. (20116725)
2010
17
In reference to Lithotripsy for refractory pediatric sialolithiasis (Laryngoscope 2009;119:298-299). (19688849)
2009
18
Diagnosis and management of sialolithiasis with a semirigid endoscope. (19272805)
2009
19
Sialolithiasis of the submandibular salivary gland treated with the 810- to 830-nm diode laser. (19099383)
2008
20
Tonsilloliths associated with sialolithiasis in the submandibular gland. (18201626)
2008
21
Oral diagnosis. Panoramic radiopacities. Sialolithiasis. (18050589)
2007
22
Submandibular duct sialolithiasis : an unusual presentation. (17007760)
2006
23
Ultrasound-guided mechanical intraductal stone fragmentation and removal for sialolithiasis: a new technique. (16437264)
2006
24
Current opinions in sialolithiasis diagnosis and treatment. (16450768)
2005
25
Characterization of lymphoid infiltrates in chronic obstructive sialadenitis associated with sialolithiasis. (15078491)
2004
26
Sialolithiasis: an unusually large submandibular salivary stone. (12199129)
2002
27
Histopathology of submandibular glands removed for sialolithiasis. (11372932)
2001
28
Sialolithiasis and salivary ductal stenosis: diagnostic accuracy of MR sialography with a three-dimensional extended-phase conjugate-symmetry rapid spin-echo sequence. (11058627)
2000
29
Laser lithotripsy: a preliminary study on its application for sialolithiasis. (7947565)
1994
30
An uncommon case of parotid sialolithiasis. (1872587)
1991
31
Bilateral submandibular sialolithiasis and concurrent sialadenitis: a case report. (1941338)
1991
32
Submandibular sialolithiasis: transoral excision. (2593220)
1989
33
Sialolithiasis of an accessory salivary gland. (2539848)
1989
34
Salivary gland function after sialolithiasis: scintigraphic examination of submandibular glands with 99mTc-pertechnetate. (2543802)
1989
35
Sialolithiasis of a Blandin's gland duct. (3133429)
1988
36
Submandibular gland sialolithiasis--sialographic and pathologic findings with evaluation using SEM and EPMA analysis. (3478426)
1987
37
Submandibular sialolithiasis in children. (6955470)
1982
38
Diagnostic use of ultrasound in sialolithiasis of the parotid gland. (7119544)
1982
39
Recurrent parotid sialolithiasis and chronic pancreatitis: report of a case. (4511079)
1973
40
Sialolithiasis of accessory salivary glands: review of 55 cases. (4507238)
1972
41
The clinical entity of sialolithiasis of the minor salivary glands. (5280619)
1971
42
Sialolithiasis of a minor salivary gland. A case report and review of the literature. (5264862)
1970
43
Sialolithiasis and enlarged genial tubercles. (5272046)
1970
44
Sialolithiasis of the minor salivary glands: report of three cases. (5238931)
1968
45
Bilateral submandibular sialolithiasis. (5216231)
1966
46
Sialographic studies on submandibular sialolithiasis. (13946669)
1963
47
Sialolithiasis with sialoadenitis of a minor salivary gland. (14002089)
1963
48
Sialolithiasis, Wharton's duct, left submaxillary gland; report of a case. (13297388)
1956
49
Etiology of sialolithiasis. (18147764)
1949
50
Sialolithiasis. (18887973)
1948

Variations for Sialolithiasis

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Expression for genes affiliated with Sialolithiasis

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Search GEO for disease gene expression data for Sialolithiasis.

Pathways for genes affiliated with Sialolithiasis

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GO Terms for genes affiliated with Sialolithiasis

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Cellular components related to Sialolithiasis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cell surfaceGO:00099868.7CD38, CD8A, FASLG, ITGA2, NOTCH1
2extracellular regionGO:00055767.9ALB, CD8A, CFP, CTGF, FASLG, NOTCH1
3extracellular spaceGO:00056157.4ALB, CFP, CTGF, FASLG, PRTN3, SEMA3G
4plasma membraneGO:00058865.8ATP2B3, CASR, CD38, CD8A, CTGF, FASLG

Biological processes related to Sialolithiasis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cellular calcium ion homeostasisGO:00068749.8ATP2B3, CASR, XK
2response to organic substanceGO:00100339.7ALB, SPP1, TIMP3
3positive regulation of cell proliferationGO:00082848.2CTGF, FASLG, LRP5, NOTCH1, PRTN3

Sources for Sialolithiasis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet