MCID: SCK001
MIFTS: 42

Sick Building Syndrome malady

Respiratory diseases category
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Summaries for Sick Building Syndrome

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Disease Ontology:8 An extrinsic allergic alveolitis that is characterized by a set of symptoms such as headache, fatigue, eye irritation, and breathing difficulties that affect workers in modern airtight office buildings. the disease is caused by indoor pollutants (as formaldehyde fumes, particulate matter, or microorganisms), and the symptoms tend to disappear when affected individuals leave the building.

MalaCards based summary: Sick Building Syndrome is related to asthma and adrenal carcinoma. An important gene associated with Sick Building Syndrome is POMC (proopiomelanocortin), and among its related pathways are Peptide hormone metabolism and Adipocytokine signaling pathway. The compounds shu 9119 and alpha msh have been mentioned in the context of this disorder. Affiliated tissues include eye, colon and endothelial, and related mouse phenotypes are tumorigenesis and immune system.

CDC:3   

Wikipedia:65 Sick building syndrome (SBS) is used to describe situations in which building occupants experience acute... more...

Aliases & Classifications for Sick Building Syndrome

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Sick Building Syndrome, Aliases & Descriptions:

Name: Sick Building Syndrome 8 10 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Respiratory diseases


External Ids:

Disease Ontology8 DOID:2710
SNOMED-CT57 19076009
MeSH34 D018877

Related Diseases for Sick Building Syndrome

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Graphical network of the top 20 diseases related to Sick Building Syndrome:



Diseases related to sick building syndrome

Symptoms for Sick Building Syndrome

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Drugs & Therapeutics for Sick Building Syndrome

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Drug clinical trials:

Search ClinicalTrials for Sick Building Syndrome

Search NIH Clinical Center for Sick Building Syndrome

Genetic Tests for Sick Building Syndrome

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Anatomical Context for Sick Building Syndrome

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MalaCards organs/tissues related to Sick Building Syndrome:

32
Eye, Colon, Endothelial

Animal Models for Sick Building Syndrome or affiliated genes

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MGI Mouse Phenotypes related to Sick Building Syndrome:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020069.0MMP9, POMC, LEP
2MP:00053878.3MMP9, POMC, LEP, IGHE
3MP:00053978.0IGHE, LEP, POMC, MMP9

Publications for Sick Building Syndrome

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Articles related to Sick Building Syndrome:

(show top 50)    (show all 192)
idTitleAuthorsYear
1
A Longitudinal Study of Sick Building Syndrome (SBS) among Pupils in Relation to SO2, NO2, O3 and PM10 in Schools in China. (25398002)
2014
2
Prevalence and risk factors of sick building syndrome among office workers. (23963091)
2013
3
Sick building syndrome by indoor air pollution in Dalian, China. (23579877)
2013
4
A longitudinal study of aldehydes and volatile organic compounds associated with subjective symptoms related to sick building syndrome in new dwellings in Japan. (22265600)
2012
5
The prevalence and incidence of sick building syndrome in Chinese pupils in relation to the school environment: a two-year follow-up study. (21615503)
2011
6
Sick building syndrome in a general hospital and the risks for pregnant workers. (21458809)
2011
7
The possible role of fungal contamination in sick building syndrome. (21196335)
2011
8
Association study between sick building syndrome and polymorphisms of seven human detoxification genes in the Japanese. (21787601)
2010
9
A longitudinal study of environmental risk factors for subjective symptoms associated with sick building syndrome in new dwellings. (19608217)
2009
10
An update on sick building syndrome. (19532093)
2009
11
Case study of volatile organic compounds in indoor air of a house before and after repair where sick building syndrome occurred. (17903361)
2007
12
Projective drawings for assessing stress among subjects with medical symptoms compatible with sick building syndrome, and validation of a modified version of the Stress Load Index from the Drawing Personality Profile: a pilot study. (17450971)
2007
13
Office work exposures [corrected] and respiratory and sick building syndrome symptoms. (17339295)
2007
14
Serum levels of volatile organic compounds in patients with sick building syndrome. (17033858)
2006
15
Associations among sick building syndrome, psychosocial factors, and personality traits. (16060437)
2005
16
Bioaerosols and sick building syndrome: particles, inflammation, and allergy. (15764903)
2005
17
A time-series study of sick building syndrome: chronic, biotoxin-associated illness from exposure to water-damaged buildings. (15681119)
2005
18
Multiple logistic regression modelling substantiates multifactor contributions associated with sick building syndrome in residential interiors in Mauritius. (12745349)
2003
19
The full circle: from the Minamata disaster to the sick building syndrome. (11564629)
2001
20
Why do women suffer from sick building syndrome more often than men?--subjective higher sensitivity versus objective causes. (11761596)
2001
21
Environmental tobacco smoke exposure and overtime work as risk factors for sick building syndrome in Japan. (11682362)
2001
22
The effects of outdoor air supply rate in an office on perceived air quality, sick building syndrome (SBS) symptoms and productivity. (11089327)
2000
23
Sick building syndrome. Indoor air quality and your patients' health. (11521615)
2000
24
The sick building syndrome. (10598396)
1999
25
Sick building syndrome. (10212636)
1999
26
The sick building syndrome as a subjective perception-theoretical approach and assessment methods. (10507132)
1999
27
Visual analogue scales for detecting changes in symptoms of the sick building syndrome in an intervention study. (10505662)
1999
28
Sick building syndrome: association of symptoms with serum IgE specific to fungi. (9561392)
1998
29
Sick-building syndrome. (9235451)
1997
30
Indoor air pollutants and sick building syndrome: a case study and implications for the community health nurse. (9078851)
1997
31
Sick building syndrome, work factors and occupational stress. (8881012)
1996
32
Fungal colonization of fiberglass insulation in the air distribution system of a multi-story office building: VOC production and possible relationship to a sick building syndrome. (8757941)
1996
33
Sick building syndrome and gender bias: imperiling women's health. (7747241)
1995
34
The Sick Building Syndrome (SBS) in office workers. A case-referent study of personal, psychosocial and building-related risk indicators. (7721522)
1994
35
Building and Home-Related Complaints and Illnesses: Sick Building Syndrome. Conference proceedings. Lake Buena Vista, Florida, December 3-5, 1992. (7915735)
1994
36
Textile wall materials and sick building syndrome. (8185388)
1994
37
Town planning & health. Sick building syndrome. (10135739)
1994
38
Building components contributors of the sick building syndrome. (8175632)
1994
39
The effect of varying levels of outdoor-air supply on the symptoms of sick building syndrome. (8441426)
1993
40
Building-related illnesses and sick building syndrome. (8089648)
1993
41
Sick building syndrome--know your ventilation rates. (10126689)
1993
42
The feasibility of using a double blind experimental cross-over design to study interventions for sick building syndrome. (1607899)
1992
43
The sick building syndrome. (1580467)
1992
44
Field studies on the sick building syndrome. (1580471)
1992
45
High prevalence of sick building syndrome in a new air-conditioned building in Italy. (1539998)
1992
46
Sick building syndrome. (1683923)
1991
47
Environmental, occupational, and personal factors related to the prevalence of sick building syndrome in the general population. (1854648)
1991
48
The sick building syndrome: where is the epidemiologic basis? (2400024)
1990
49
Sick building syndrome. (2616483)
1989
50
The sick building syndrome. (3917804)
1985

Variations for Sick Building Syndrome

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Expression for genes affiliated with Sick Building Syndrome

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Expression patterns in normal tissues for genes affiliated with Sick Building Syndrome

Search GEO for disease gene expression data for Sick Building Syndrome.

Pathways for genes affiliated with Sick Building Syndrome

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Pathways related to Sick Building Syndrome according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.6POMC, LEP
29.6POMC, LEP
3
Show member pathways
9.6POMC, LEP
49.5MMP9, LEP

Compounds for genes affiliated with Sick Building Syndrome

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Compounds related to Sick Building Syndrome according to GeneCards/GeneDecks:

(show top 50)    (show all 73)
idCompoundScoreTop Affiliating Genes
1shu 911961 4411.0POMC, LEP
2alpha msh4410.0LEP, POMC
3megestrol acetate4410.0LEP, POMC
4topiramate44 50 24 1113.0LEP, POMC
5thiopental44 1111.0POMC, LEP
6fenfluramine44 28 1112.0POMC, LEP
7cortisone44 2410.9POMC, LEP
811beta-hydroxysteroid449.9POMC, LEP
9naloxone44 28 50 1112.9POMC, LEP
10dehydroepiandrosterone sulfate449.9LEP, POMC
11clonidine44 50 28 1112.9POMC, LEP
128-isoprostane449.8LEP, MMP9
13fenofibrate44 50 1111.7MMP9, LEP
14beclomethasone dipropionate449.7POMC, IGHE
15ribavirin44 50 1111.6MMP9, LEP
16dhea449.6POMC, LEP
17heroin44 50 1111.6IGHE, POMC
18propofol44 50 1111.5POMC, IGHE
19metformin44 50 1111.5POMC, LEP
20gnrh449.5RGS3, POMC, LEP
21gaba449.5MMP9, POMC, LEP
22paraffin449.4MMP9, POMC, LEP
23ganciclovir44 1110.3POMC, LEP
24ivig449.3MMP9, IGHE
25budesonide44 50 1111.2POMC, LEP, IGHE
26thyroxine44 2410.2IGHE, LEP, POMC
27capsaicin44 2810.2IGHE, LEP
28glycerol44 24 1111.2POMC, LEP, IGHE
29fluticasone propionate44 50 61 1112.2IGHE, POMC, MMP9
30ascorbic acid44 2410.1IGHE, LEP, POMC
31indomethacin44 28 61 1112.1POMC, LEP, IGHE
32l-nmma449.1IGHE, LEP, MMP9
33acetylcholine44 50 28 24 1113.1POMC, LEP, IGHE
34inositol449.1MMP9, LEP, IGHE
35nicotine44 28 50 1112.1MMP9, LEP, IGHE
36vitamin a44 24 1111.1MMP9, LEP, IGHE
37methotrexate50 44 1111.1IGHE, LEP, MMP9
38n acetylcysteine449.0MMP9, LEP, IGHE
39heparin44 28 24 1112.0IGHE, LEP, POMC
40aspartate448.9MMP9, POMC, IGHE
41adenylate448.8MMP9, POMC, IGHE
42epinephrine44 24 1110.7MMP9, POMC, LEP, IGHE
43norepinephrine44 24 1110.7MMP9, POMC, LEP, IGHE
44cyclosporin a44 28 6110.7MMP9, POMC, LEP, IGHE
45creatinine448.7IGHE, LEP, POMC, MMP9
46cycloheximide448.7IGHE, LEP, POMC, MMP9
47testosterone44 61 24 1111.7IGHE, LEP, POMC, MMP9
48dexamethasone44 50 28 1111.7MMP9, POMC, LEP, IGHE
49vegf448.7IGHE, LEP, POMC, MMP9
50estrogen448.6IGHE, LEP, POMC, MMP9

GO Terms for genes affiliated with Sick Building Syndrome

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Cellular components related to Sick Building Syndrome according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:0056159.1MMP9, POMC, LEP
2extracellular regionGO:0055768.0MMP9, POMC, LEP, IGHE

Biological processes related to Sick Building Syndrome according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1regulation of blood pressureGO:0082179.6POMC, LEP

Molecular functions related to Sick Building Syndrome according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1hormone activityGO:0051799.6POMC, LEP

Products for genes affiliated with Sick Building Syndrome

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Sources for Sick Building Syndrome

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet