SND
MCID: SCK002
MIFTS: 50

Sick Sinus Syndrome (SND) malady

Categories: Genetic diseases, Cardiovascular diseases, Muscle diseases, Rare diseases

Aliases & Classifications for Sick Sinus Syndrome

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Aliases & Descriptions for Sick Sinus Syndrome:

Name: Sick Sinus Syndrome 11 25 27 50 39 13 68
Sinus Node Dysfunction 25 27 68
Sinus Node Infection 11
 
Sinus Node Disease 25
Snd 25
Sss 25

Classifications:



External Ids:

Disease Ontology11 DOID:13884
ICD1030 I49.5
MeSH39 D012804
NCIt45 C62244

Summaries for Sick Sinus Syndrome

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Genetics Home Reference:25 Sick sinus syndrome (also known as sinus node dysfunction) is a group of related heart conditions that can affect how the heart beats. "Sick sinus" refers to the sino-atrial (SA) node, which is an area of specialized cells in the heart that functions as a natural pacemaker. The SA node generates electrical impulses that start each heartbeat. These signals travel from the SA node to the rest of the heart, signaling the heart (cardiac) muscle to contract and pump blood. In people with sick sinus syndrome, the SA node does not function normally. In some cases, it does not produce the right signals to trigger a regular heartbeat. In others, abnormalities disrupt the electrical impulses and prevent them from reaching the rest of the heart.

MalaCards based summary: Sick Sinus Syndrome, also known as sinus node dysfunction, is related to sick sinus syndrome 1 and sick sinus syndrome 2. An important gene associated with Sick Sinus Syndrome is SCN5A (Sodium Voltage-Gated Channel Alpha Subunit 5), and among its related pathways are Antiarrhythmic Pathway, Pharmacodynamics and Cardiac Progenitor Differentiation. Affiliated tissues include heart, testes and atrioventricular node, and related mouse phenotypes are Increased shRNA abundance (Z-score > 2) and cardiovascular system.

Wikipedia:71 Sick sinus syndrome (SSS), also called sinus dysfunction, or sinoatrial node disease (\"SND\"), is a... more...

Related Diseases for Sick Sinus Syndrome

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Diseases in the Sick Sinus Syndrome family:

Sick Sinus Syndrome 1 Sick Sinus Syndrome 3
Sick Sinus Syndrome 2 Familial Sick Sinus Syndrome

Diseases related to Sick Sinus Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 79)
idRelated DiseaseScoreTop Affiliating Genes
1sick sinus syndrome 112.4
2sick sinus syndrome 212.4
3sick sinus syndrome 312.4
4familial sick sinus syndrome12.2
5sinus node disease and myopia12.0
6isolated levocardia11.3
7chronic atrial and intestinal dysrhythmia11.2
8cardiac arrhythmia, ankyrin-b-related10.9
9atrial fibrillation10.4
10syncope10.3
11atrioventricular block10.2
12lipodystrophy, familial partial, type 510.2HCN4, SCN5A
13uterine fibroid10.1HCN4, SCN5A
14third-degree atrioventricular block10.1HCN4, SCN5A
15amyloidosis10.1
16lymphoma10.0
17synostosis10.0F2, XK
18optic nerve disease10.0F2, MYH6
19brugada syndrome10.0
20cardiomyopathy10.0
21antley-bixler syndrome9.9HCN4, RANGRF, SCN5A
22hemorrhagic shock and encephalopathy syndrome9.9SCN5A, XK
23micturation-induced seizures9.9AGT, HCN4, MYH6, SCN5A
24heart disease9.9
25adams-oliver syndrome9.9AGT, F2, HCN4, SCN5A
26myocardial infarction9.8
27artery disease9.8
28pericarditis9.8
29dextrocardia9.8
30myotonic dystrophy9.8
31polymyositis9.8
32levocardia9.8
33familial periodic paralysis9.8F2, HCN4, SCN5A, SHOX2
34brachyolmia type 39.7MYH6, SHOX2, TBX3
35coronary artery disease9.7
36hodgkin lymphoma9.7
37hemochromatosis9.7
38ebstein anomaly9.7
39acute myocardial infarction9.7
40arteriovenous fistula9.7
41atherosclerosis9.7
42cataract9.7
43dilated cardiomyopathy9.7
44sinoatrial node disease9.7
45crest syndrome9.7
46cardiac arrest9.7
47esophagitis9.7
48conduct disorder9.7
49typhoid fever9.7
50scrub typhus9.7

Graphical network of the top 20 diseases related to Sick Sinus Syndrome:



Diseases related to sick sinus syndrome

Symptoms & Phenotypes for Sick Sinus Syndrome

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GenomeRNAi Phenotypes related to Sick Sinus Syndrome according to GeneCards Suite gene sharing:

26
idDescriptionGenomeRNAi Source AccessionScoreTop Affiliating Genes
1GR00366-A-19210.2F2, SCN5A, SHOX2

MGI Mouse Phenotypes related to Sick Sinus Syndrome according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053858.5AGT, F2, HCN4, MYH6, SCN5A, SHOX2
2MP:00053697.9AGT, HCN4, MYH6, SCN5A, TBX3, XK
3MP:00107687.5AGT, F2, HCN4, MYH6, SCN5A, SGO1

Drugs & Therapeutics for Sick Sinus Syndrome

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Drugs for Sick Sinus Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 56)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
PropafenoneapprovedPhase 43054063-53-54932
Synonyms:
1-(2-(2-Hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-1-propanone
1-(2-(2-Hydroxy-3-propylaminopropoxy)phenyl)-3-phenylpropan-1-one
1-[2-(2-Hydroxy-3-(propylamino)propoxy)phenyl]-3-phenyl-1-propanone hydrochloride
1-[2-(2-Hydroxy-3-[propylamino]- propoxy)phenyl]-3-phenyl-1-propanone
1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenylpropan-1-one
107300-59-4
2-(2'-Hydroxy-3'-propylaminopropoxy)-omega-phenylpropiophenone
34183-22-7 (hydrochloride)
54063-53-5
AB00053687
AC1L1J9C
AKOS000276940
BCBcMAP01_000079
BPBio1_000437
BRD-A26334849-001-02-1
BRD-A26334849-003-05-0
BSPBio_000397
BSPBio_001465
BSPBio_003470
C07381
CHEBI:127112
CHEMBL631
CID4932
CPD001453705
D08435
DB01182
DivK1c_000906
EINECS 258-955-6
HMS1791J07
HMS1989J07
HMS2089E09
IDI1_000906
KBio1_000906
KBio2_002092
KBio2_004660
KBio2_007228
KBio3_002974
KBioGR_000817
KBioSS_002092
 
LS-123071
Lopac0_000919
MolPort-000-881-283
MolPort-002-545-323
NCGC00015819-10
NCGC00089784-02
NCGC00089784-03
NCGC00089784-04
NCGC00089784-05
NINDS_000906
P4670_SIGMA
Prestwick0_000499
Prestwick1_000499
Prestwick2_000499
Prestwick3_000499
Propafenon Hexal
Propafenon hexal (TN)
Propafenona
Propafenona [INN-Spanish]
Propafenone (INN)
Propafenone HCl
Propafenone [INN:BAN]
Propafenone hydrochloride
Propafenone-HCl
Propafenonum
Propafenonum [INN-Latin]
Rythmol
Rythmol SR
S2500_Selleck
SAM002564228
SBB067234
SPBio_001605
SPBio_002318
Spectrum2_001603
Spectrum3_001905
Spectrum4_000209
Spectrum5_001271
Spectrum_001612
UNII-68IQX3T69U
propafenone
2
Amiodaroneapproved, investigationalPhase 41221951-25-32157
Synonyms:
(2-Butyl-3-benzofuranyl)(4-(2-(diethylamino)ethoxy)-3,5-diidophenyl)methanone
(2-butyl-1-benzofuran-3-yl)(4-{[2-(diethylamino)ethyl]oxy}-3,5-diiodophenyl)methanone
(2-butyl-1-benzofuran-3-yl)-[4-(2-diethylaminoethyloxy)-3,5-diiodophenyl]methanone
(2-butyl-1-benzofuran-3-yl){4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl}methanone
(2-butylbenzofuran-3-yl)-[4-(2-diethylaminoethoxy)-3,5-diiodo-phenyl]-methanone
(2-{4-[(2-butyl-1-benzofuran-3-yl)carbonyl]-2,6-diiodophenoxy}ethyl)diethylamine
1951-25-3
2-Butyl-3-(3,5-diiodo-4-(2-diethylaminoethoxy)benzoyl)benzofuran
2-Butyl-3-(3,5-diiodo-4-(beta-diethylaminoethoxy)benzoyl)benzofuran
2-Butyl-3-(4'-beta-N-diethylaminoethoxy-3',5'-diiodobenzoyl)benzofuran
2-Butyl-3-[3,5-diiodo-4-(2-di
2-Butyl-3-benzofuranyl 4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl ketone
2-Butyl-3-benzofuranyl p-((2-diethylamino)ethoxy)-m,m-diiodophenyl ketone
2-Butyl-3-benzofuranyl p-[(2-diethylamino)ethoxy]-m,m-diiodophenyl ketone
2-N-Butyl-3',5'-diiodo-4'-N-diethylaminoethoxy-3-benzoylbenzofuran
2-n-Butyl-3',5'-diiodo-4'-N-diethylaminoethoxy-3-benzoylbenzofuran
5-18-02-00353 (Beilstein Handbook Reference)
AB00053422
AC1L1D1R
AC1Q2VCU
ASTA Medica Brand of Amiodarone Hydrochloride
Alphapharm Brand of Amiodarone Hydrochloride
Amidorone
Aminodarone
Amio-Aqueous IV
Amiobeta
Amiodarex
Amiodarona
Amiodarona [INN-Spanish]
Amiodarone
Amiodarone (USAN/INN)
Amiodarone Base
Amiodarone HCL
Amiodarone Hydrochloride
Amiodarone [USAN:BAN:INN]
Amiodarons
Amiodaronum
Amiodaronum [INN-Latin]
Amiohexal
Amjodaronum
Ancar
Aratac
Armstrong Brand of Amiodarone Hydrochloride
Arycor
BIDD:GT0425
BIDD:PXR0146
BPBio1_000372
BRN 1271711
BSPBio_000338
BSPBio_001574
BSPBio_002580
Berenguer Infale Brand of Amiodarone Hydrochloride
Betapharm Brand of Amiodarone Hydrochloride
Bio1_000026
Bio1_000515
Bio1_001004
Bio2_000294
Bio2_000774
Braxan
C06823
C25H29I2NO3
CAS-19774-82-4
CBiol_001740
CHEBI:2663
CHEMBL633
CID2157
Corbionax
Cordarex
Cordarone
Cordarone Intravenous
D000638
D02910
DB01118
DivK1c_000079
EINECS 217-772-1
 
G Gam Brand of Amiodarone Hydrochloride
HMS1791O16
HMS1989O16
HMS2089C07
Hexal Brand of Amiodarone Hydrochloride
IDI1_000079
IDI1_034044
KBio1_000079
KBio2_000294
KBio2_000741
KBio2_002862
KBio2_003309
KBio2_005430
KBio2_005877
KBio3_000587
KBio3_000588
KBio3_001800
KBioGR_000294
KBioGR_001859
KBioSS_000294
KBioSS_000741
Ketone, 2-butyl-3-benzofuranyl 4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl
Ketone, 2-butyl-3-benzofuranyl 4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl (7CI,8CI)
Kordaron
L 3428
L-3428
L001174
L3428
LS-87088
Labaz
Leurquin Brand of Amiodarone Hydrochloride
Lopac-A-8423
Lopac0_000122
MolPort-003-703-670
NCGC00015096-01
NCGC00015096-02
NCGC00015096-03
NCGC00015096-10
NCGC00024242-03
NCGC00024242-04
NCGC00024242-05
NCGC00024242-06
NCI60_041885
NINDS_000079
Ortacrone
Pacerone
Pharma Investi Brand of Amiodarone Hydrochloride
Prestwick0_000409
Prestwick1_000409
Prestwick2_000409
Prestwick3_000409
QTL1_000008
Rytmarone
SKF 33134-A
SKF 33134A
SPBio_001825
SPBio_002277
STK529812
STOCK1S-12240
Sanofi Winthrop Brand of Amiodarone Hydrochloride
Sedacoron
Sedacorone
Spectrum2_001813
Spectrum3_001050
Spectrum4_001190
Spectrum5_001533
Spectrum_000261
Tachydaron
UNII-N3RQ532IUT
UNM000001215003
Wyeth Brand of Amiodarone Hydrochloride
amiodarone
ethylaminoethoxy)benzoyl]benzofuran
nchembio.79-comp9
nchembio732-comp1
on
pms-Amiodarone
3
SotalolapprovedPhase 440959-24-0, 3930-20-95253
Synonyms:
.beta.-Cardone
27948-47-6
3930-20-9
4'-(1-Hydroxy-2-(isopropylamino)ethyl)methane sulfonanilide
4'-(1-Hydroxy-2-isopropylaminoethyl)methanesulfonanilid
959-24-0 (mono-hydrochloride)
AB00514715
AC-19021
AC1L1JXU
BPBio1_001069
BRD-A33168282-003-03-2
BSPBio_000971
Betapace
Betapace AF
C07309
C12H20N2O3S
CCRIS 4204
CHEMBL471
CID5253
D08525
DB00489
Darob mite
Darob mite (TN)
HMS2089K09
L013427
LS-90249
Lopac0_001055
 
MJ-1999
Methanesulfonamide, N-(4-(1-hydroxy-2-((1-methylethyl)amino)ethyl)phenyl)- (9CI)
MolPort-002-042-381
N-(4-{1-hydroxy-2-[(1-methylethyl)amino]ethyl}phenyl)methanesulfonamide
N-[4-[1-hydroxy-2-(propan-2-ylamino)ethyl]phenyl]methanesulfonamide
N-{4-[1-hydroxy-2-(propan-2-ylamino)ethyl]phenyl}methanesulfonamide
NCGC00015919-05
NCGC00024899-02
NCGC00024899-03
Prestwick0_000966
Prestwick1_000966
Prestwick2_000966
Prestwick3_000966
SBB066409
SPBio_002892
Sorine
Sotalol
Sotalol (INN)
Sotalol HCL
Sotalol Monohydrochloride
Sotalol [INN:BAN]
Sotalolo
Sotalolum
Sotalolum [INN-Latin]
UNII-A6D97U294I
beta-Cardone
d,l-Sotalol
sotalol
4
EthanolapprovedPhase 4213764-17-5702
Synonyms:
(C6-C9)Alkyl alcohol
02483_FLUKA
02851_FLUKA
02853_FLUKA
02854_FLUKA
02855_FLUKA
02856_FLUKA
02856_SIAL
02857_FLUKA
02857_SIAL
02858_FLUKA
02858_SIAL
02860_FLUKA
02865_FLUKA
02865_SIAL
02870_FLUKA
02870_SIAL
02875_FLUKA
02877_FLUKA
02878_FLUKA
02882_FLUKA
02882_SIAL
02883_FLUKA
02884_FLUKA
02890_FLUKA
02890_SIAL
02891_FLUKA
02891_SIAL
1-Hydroxyethane
100C.NPA
121182-78-3
187380_ALDRICH
187380_SIAL
24102_RIEDEL
24102_SIAL
24103_RIEDEL
24103_SIAL
24105_RIEDEL
24105_SIAL
24106_RIEDEL
24106_SIAL
24194_RIEDEL
24194_SIAL
245119_ALDRICH
245119_SIAL
270741_ALDRICH
270741_SIAL
277649_ALDRICH
277649_SIAL
2858_SIGMA
29221_FLUKA
32205_RIEDEL
32205_SIAL
32221_RIEDEL
32221_SIAL
32294_RIEDEL
32294_SIAL
34870_SIAL
34963_RIEDEL
39278_FLUKA
40210_ALDRICH
40210_RIEDEL
41322_FLUKA
458600_ALDRICH
458600_SIAL
459828_ALDRICH
459828_SIAL
459836_ALDRICH
459836_SIAL
459844_SIAL
48075_SUPELCO
493511_SIAL
493538_ALDRICH
493538_SIAL
493546_ALDRICH
493546_SIAL
64-17-5
676829_SIAL
68475-56-9
71076-86-3
71329-38-9
8000-16-6
8024-45-1
AC1L19TW
AC1Q31MM
AHD 2000
AI3-01706
ALCOHOL 5% IN D5-W
Absolute Alcohol
Absolute Ethanol
Absolute alcohol
Absolute ethanol
Absolute ethyl alcohol
Aethanol
Aethanol [German]
Aethylalkohol
Alcare Hand Degermer
Alcohol
Alcohol (USP)
Alcohol (ethyl)
Alcohol Anhydrous
Alcohol [USP]
Alcohol anhydrous
Alcohol dehydrated
Alcohol denatured
Alcohol etílico
Alcohol, Absolute
Alcohol, Dehydrated
Alcohol, Diluted
Alcohol, Grain
Alcohol, anhydrous
Alcohol, dehydrated
Alcohol, denatured
Alcohol, diluted
Alcohol, ethyl
Alcohols
Alcohols, C1-3
Alcohols, C30
Alcohols, C6-9
Alcool Ethylique
Alcool Etilico
Alcool ethylique
Alcool etilico
Alcool éthylique
Algrain
Alkohol
Alkohol [German]
Alkoholu Etylowego
Alkoholu etylowego
Aminoethanol
Anhydrol
Anhydrol PM 4085
Anhydrous alcohol
Anhydrous ethanol
Beta-Aminoethanol
Beta-Aminoethyl Alcohol
Beta-Ethanolamine
Beta-Hydroxyethylamine
C00469
C2H5OH
C2H6O
CCRIS 945
CDA 19
CDA 19-200
CHEBI:16236
CHEMBL545
CID702
Caswell No. 426
Caswell No. 430
Colamine
Cologne Spirit
Cologne spirit
Cologne spirits
 
D000431
D00068
DB00898
Dehydrated Ethanol
Dehydrated alcohol
Dehydrated ethanol
Denatured Alcohol
Denatured Alcohol Cd-10
Denatured Alcohol Cd-5
Denatured Alcohol Cd-5a
Denatured Alcohol Sd-1
Denatured Alcohol Sd-13a
Denatured Alcohol Sd-17
Denatured Alcohol Sd-23a
Denatured Alcohol Sd-28
Denatured Alcohol Sd-30
Denatured Alcohol Sd-39b
Denatured Alcohol Sd-39c
Denatured Alcohol Sd-3a
Denatured Alcohol Sd-40m
Denatured Ethanol
Denatured alcohol
Denatured ethanol
Desinfektol EL
Diluted Alcohol
Distilled spirits
E2385_SIGMA
E7023_ALDRICH
E7023_SIAL
E7148_ALDRICH
E7148_SIAL
E7517_SIGMA
EINECS 200-578-6
EINECS 270-649-4
EOH
EOX
ETA
Envision Conditioner Pdd 9020
Esumiru WK 88
EtOH
Etanolo
Etanolo [Italian]
Ethanol (9CI)
Ethanol 200 Proof
Ethanol 200 proof
Ethanol Absolute
Ethanol Absolute Bp
Ethanol Anhydrous
Ethanol Extra Pure
Ethanol Vapor
Ethanol [JAN]
Ethanol solution
Ethanol, Silent Spirit
Ethanol, undenatured
Ethanolum anhydricum
Ethicap
Ethyl Alcohol
Ethyl Alcohol & Water, 10%
Ethyl Alcohol & Water, 20%
Ethyl Alcohol & Water, 30%
Ethyl Alcohol & Water, 40%
Ethyl Alcohol & Water, 5%
Ethyl Alcohol & Water, 50%
Ethyl Alcohol & Water, 60%
Ethyl Alcohol & Water, 70%
Ethyl Alcohol & Water, 80%
Ethyl Alcohol & Water, 95%
Ethyl Alcohol & Water, 96%
Ethyl Alcohol Anhydrous
Ethyl Alcohol, Anhydrous
Ethyl Alcohol, Denatured
Ethyl Hydrate
Ethyl Hydroxide
Ethyl alc
Ethyl alcohol
Ethyl alcohol anhydrous
Ethyl alcohol in alcoholic beverages
Ethyl alcohol usp
Ethyl hydrate
Ethyl hydroxide
Ethylalcohol
Ethylalcohol [Dutch]
Ethylol
Ethylolamine
Ethyloxy Group
Etylowy alkohol
FEMA No. 2419
FEMA Number 2419
Fermentation alcohol
Glycinol
Grain alcohol
HSDB 531
HSDB 82
HYDROXYETHYL GROUP
Hinetoless
Hydroxyethane
I14-12648
IMS 99
Infinity Pure
Jaysol
Jaysol S
LS-1539
LTBB002977
Lux
Methylated Spirit Mineralised
Methylated spirit
Methylcarbinol
MolPort-001-785-844
Molasses alcohol
NCGC00091458-01
NCI-C03134
NSC 85228
NSC85228
Oxydimethylene Group
Potato alcohol
Punctilious ethyl alcohol
Pyro
QMHAIh@
Reagent Alcohol
Ru-Tuss Expectorant
SDA 3A
SDA 40-2
SDM No. 37
SY Fresh M
Sekundasprit
Silent spirit
Spirit
Spirits of wine
Spiritus vini
Spirt
Synasol
Tecsol
Tecsol C
Thanol
Thiofaco M-50
UNII-3K9958V90M
USAF EK-1597
Undenatured Ethanol
WLN: Q2
absolute alcohol
alcohol
alcohol etilico
bmse000297
etanol
ethanol
ethyl alcohol
grain alcohol
nchem.651-comp3c
nchembio.552-comp10
nchembio.94-comp20
spiritus vini
Äthanol
Äthylalkohol
éthanol
5Potassium Channel BlockersPhase 4180
6Neurotransmitter AgentsPhase 4, Phase 318340
7Peripheral Nervous System AgentsPhase 4, Phase 323689
8Sodium Channel BlockersPhase 41593
9SympatholyticsPhase 4, Phase 3580
10Diuretics, Potassium SparingPhase 41917
11Vasodilator AgentsPhase 43543
12Cytochrome P-450 Enzyme InhibitorsPhase 4, Phase 33917
13Anti-Arrhythmia AgentsPhase 4, Phase 33093
14Adrenergic beta-AntagonistsPhase 4, Phase 31193
15Adrenergic AntagonistsPhase 4, Phase 31573
16Autonomic AgentsPhase 4, Phase 310150
17Cytochrome P-450 CYP1A2 InhibitorsPhase 4, Phase 3572
18Cytochrome P-450 CYP3A InhibitorsPhase 41715
19Adrenergic AgentsPhase 4, Phase 35352
20Cytochrome P-450 CYP2D6 InhibitorsPhase 4727
21Cytochrome P-450 CYP2C9 InhibitorsPhase 4669
22
LosartanapprovedPhase 3286114798-26-43961
Synonyms:
(2-Butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazol-5-yl)methanol
(2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-1H-imidazol-5-yl)methanol
(2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazol-5-yl)methanol
114798-26-4
124750-99-8 (mono-potassium salt)
1H-Imidazole-5-methanol, 2-butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]- (9CI)
2-Butyl-4-chloro-1-((2'-(1H-etrazol-5-yl) (1,1'-biphenyl)-4-yl)methyl)-1H-imidazole-5-methanol
2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl-1H-imidazole-5-methanol
2-N-Butyl-4-chloro-5-hydroxymethyl-1-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]imidazole
2-butyl-4-chloro-1-[p-(o-1H-tetrazol-5ylphenyl)benzyl]imidazole-5-methanol
2-n-butyl-4-chloro-5-hydroxymethyl-1-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]imidazole
2-n-butyl-4-chloro-5-hydroxymethyl-1-[[2'-(1H-tetrazol-5-yl)-biphenyl-4-yl]methyl]imidazole
AC1L1H3Q
BIDD:GT0286
BRD-K76205745-001-02-5
BSPBio_002695
C07072
C22H23ClN6O
CHEBI:6541
CHEMBL191
CID3961
CL23623
Cozaar
D08146
DB00678
DUP 89
DuP 89
DuP-753
HMS1922J13
HMS2093E22
Hyzaar
I14-9710
Jsp001094
KBio2_002193
 
KBio2_004761
KBio2_007329
KBio3_001915
KBioGR_001611
KBioSS_002193
L000351
LOSARTAN POTASSIUM
LS-78746
Lacidipine
Lortaan
Losartan
Losartan (INN)
Losartan Potassium
Losartan [INN:BAN]
Losartan monopotassium salt
Losartic
Losartic (TN)
MK-954
MK954
MolPort-003-666-553
NCGC00095125-01
NCGC00095125-02
NCGC00095125-03
Oprea1_644635
SPBio_001893
SPECTRUM1504268
Spectrum2_001677
Spectrum3_000998
Spectrum4_001126
Spectrum5_001466
Spectrum_001713
UNII-JMS50MPO89
[2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol
losartan
losartan potassium
23
AtenololapprovedPhase 310429122-68-72249
Synonyms:
( inverted question mark)-Atenolol
(+-)-4-(2-Hydroxy-3-isopropylaminopropoxy)phenylacetamide
(+-)-Atenolol
(+/-)-4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide
(1)-2-(4-(2-Hydroxy-3-(isopropylamino)propoxy)phenyl)acetamide
(?)-Atenolol
1-p-Carbamoylmethylphenoxy-3-isopropylamino-2-propanol
2-(4-(2-Hydroxy-3-isopropylaminopropoxy)phenyl)acetamid
2-(4-{2-hydroxy-3-[(propan-2-yl)amino]propoxy}phenyl)acetamide
2-(p-(2-Hydroxy-3-(isopropylamino)propoxy)phenyl)acetamide
2-[4-(2-Hydroxy-3-isopropylaminopropoxy)phenyl]acetamide
2-[4-({2-hydroxy-3-[(1-methylethyl)amino]propyl}oxy)phenyl]acetamide
2-[4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]acetamide
2-{4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl}acetamide
29122-68-7
4-(2-Hydroxy-3-((1-methylethyl)amino)propoxy)benzeneacetamide
4-[2 -Hydroxy-3 -(isopropylamino)-propoxy]phenylacetamide
4-[2'-Hydroxy-3'-(isopropylamino)propoxy]phenylacetamide
60966-51-0
A 7655
A7655_SIGMA
AC-11142
AC1L1D99
AC1Q1QBX
AKOS005111050
ARONIS23884
Acetamide,2-(p-(2-hydroxy-3-(isopropylamino)propoxy)phenyl)
Aircrit
Alinor
Altol
Anselol
Antipressan
Apo-Atenolol
Atcardil
Atecard
Atehexal
Atenblock
Atendol
Atenet
Ateni
Atenil
Atenol
Atenol 1A Pharma
Atenol 1A pharma
Atenol AL
Atenol Acis
Atenol Atid
Atenol CT
Atenol Cophar
Atenol Fecofar
Atenol GNR
Atenol Gador
Atenol Genericon
Atenol Heumann
Atenol MSD
Atenol NM Pharma
Atenol Nordic
Atenol PB
Atenol Quesada
Atenol Stada
Atenol Tika
Atenol Trom
Atenol Von CT
Atenol acis
Atenol ct
Atenol von ct
Atenol-Mepha
Atenol-Ratiopharm
Atenol-Wolff
Atenol-ratiopharm
Atenolin
Atenolol (JAN/USP)
Atenolol (JP15/USP/INN)
Atenolol [USAN:BAN:INN:JAN]
Atenolol [USAN:INN:BAN:JAN]
Atenololum
Atenololum [INN-Latin]
Atenomel
Atereal
Aterol
BB_SC-1519
BIM-0050109.0001
BRD-A20239487-001-02-5
BRN 2739235
BSPBio_002915
Betablok
Betacard
Betasyn
Betatop GE
Betatop Ge
Blocotenol
Blokium
CCRIS 4196
CHEBI:2904
CHEMBL24
CID2249
CPD000036768
Cardaxen
Cardiopress
Corotenol
Cuxanorm
D001262
D00235
DB00335
DivK1c_000057
Duraatenolol
Duratenol
 
EINECS 249-451-7
EINECS 262-544-7
EU-0100121
Evitocor
Farnormin
Felo-Bits
HMS1569L13
HMS1921H09
HMS2090I19
HMS2092D19
HMS500C19
HSDB 6526
Hipres
Hypoten
I01-3572
ICI 66,082
ICI 66082
ICI-66082
ICI66082
IDI1_000057
Ibinolo
InChI=1/C14H22N2O3/c1-10(2)16-8-12(17)9-19-13-5-3-11(4-6-13)7-14(15)18/h3-6,10,12,16-17H,7-9H2,1-2H3,(H2,15,18)
Internolol
Jenatenol
Juvental
KBio1_000057
KBio2_001844
KBio2_004412
KBio2_006980
KBio3_002415
KBioGR_000790
KBioSS_001844
L000116
LS-28557
LS-9707
Lo-Ten
Lo-ten
Lopac0_000121
Loten
Lotenal
MLS000069622
MLS001066372
MLS001074163
MLS001304038
MolPort-001-792-717
Myocord
NCGC00015007-07
NCGC00015007-13
NCGC00024566-03
NCGC00024566-04
NCGC00024566-05
NCGC00024566-06
NCGC00024566-07
NINDS_000057
Neatenol
Normalol
Normiten
Noten
Oprea1_448775
Oraday
Ormidol
Panapres
Plenacor
Premorine
Prenolol
Prenormine
Prinorm
SAM002564193
SMR000036768
SPBio_001482
SPECTRUM1501127
STK528649
Scheinpharm Atenol
Seles Beta
Seles beta
Selobloc
Serten
Servitenol
Spectrum2_001411
Spectrum3_001448
Spectrum4_000435
Spectrum5_001509
Spectrum_001364
Stermin
Tenidon
Teno-Basan
Teno-basan
Tenobloc
Tenoblock
Tenolol
Tenoprin
Tenoretic
Tenormin
Tenormin (TN)
Tenormine
Tenormine [French]
Tensimin
Tensotin
Tredol
UNII-50VV3VW0TI
Unibloc
Uniloc
Vascoten
Vericordin
Wesipin
Xaten
atenolol
benzeneacetamide, 4-[2'-hydroxy-3
duratenol
24
Cephalexinapproved, vet_approvedPhase 35115686-71-227447
Synonyms:
(6R,7R)-7-{[(2R)-2-amino-2-phenylacetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
105879-42-3 (mono-hydrochloride, mono-hydrate)
105879-42-3 (mono-hydrochloride,mono-hydrate)
14101-75-8
15686-71-2
15686-71-2 (Parent)
17692-47-6
23325-78-2
23325-78-2 (mono-hydrate)
38932-40-0 (mono-hydrochloride salt)
66905-57-5 (di-hydrate)
7-(D-2-Amino-2-phenylacetamido)-3-methyl-delta (sup 3)-cephem-4- carboxylic acid
7-(D-2-Amino-2-phenylacetamido)-3-methyl-delta3-cephem-4-carboxylic acid
7-(D-alpha-Aminophenylacetamido)desacetoxycephalosporanic acid
7-beta-(D-alpha-Amino-alpha-phenylacetylamino)-3-methyl-3-cephem-4-carboxylic acid
AC1L1D8M
AC1L1Y1M
AC1O6OSE
AKOS004119846
Adcadina
Ades[prex
Alcephin
Alexin
Alsporin
Ambal
Anhydrous cefalexin
Anhydrous cephalexin
Aristosporin
Azabort
BB_NC-1052
BPBio1_000501
BRD-K90733503-002-03-6
BRN 0965503
BSPBio_000455
Bactopenor
Beliam
Biocef
C06895
C08099
C16H17N3O4S
CEX
CHEBI:3534
CHEBI:3535
CHEMBL1200544
CHEMBL1727
CID27447
CID62921
CID6560168
CPD-9227
CPD000338536
Carnosporin
Cefa-iskia
Cefablan
Cefacet
Cefadal
Cefadin
Cefadina
Cefalekey
Cefaleksin
Cefalessina
Cefalessina [DCIT]
Cefalexgobens
Cefalexin
Cefalexin (JP15)
Cefalexin Scand Pharm
Cefalexin Sodium
Cefalexin anhydrous
Cefalexin generics
Cefalexina
Cefalexina Northia
Cefalexina Richet
Cefalexina [INN-Spanish]
Cefalexine
Cefalexine [INN-French]
Cefalexinum
Cefalexinum [INN-Latin]
Cefalin
Cefalival
Cefaloto
Cefaseptin
Cefax
Ceffanex
Cefibacter
Ceflax
Ceforal
Cefovit
Celexin
Cepastar
Cepexin
Cephacillin
Cephalex von ct
Cephalexin (USP)
Cephalexin (anhydrous)
Cephalexin 1-hydrate
Cephalexin 1-wasser
Cephalexin [USAN:BAN]
Cephalexin anhydrous
Cephalexin hydrate
Cephalexin monohydrate
Cephalexin, (6R-(6alpha,7beta))-Isomer
Cephalexine
Cephalexinum
Cephalobene
Cephanasten
Cephaxin
Cephin
Cepol
Ceporex
Ceporex Forte
Ceporexin
Ceporexin-E
Ceporexine
Check
Cophalexin
Cusisporina-Cefalox
Céfalexine
D00263
 
D00906
DB00567
Domucef
Doriman
Durantel
Durantel DS
EINECS 239-773-6
Ed A-Ceph
Efemida
Erocetin
Factagard
Felexin
Fexin
HMS1569G17
HMS2051A04
HSDB 3022
Henina Oral
Ibilex
Ibrexin
Inphalex
KS-1134
Karilexina
Kefalospes
Keflet
Keflex
Keflex (TN)
Kefolan
Keforal
Keftab
Keftab (TN)
Kekrinal
Kidolex
L-Keflex
LS-149963
LS-173992
LS-174191
Lafarine
Larixin
Lenocef
Lexibiotico
Lilly 66873
Loisine
Lonflex
Lopilexin
Losporal
MLS000759527
Madlexin
Maksipor
Mamalexin
Mamlexin
Medolexin
Medoxine
MolPort-002-507-304
MolPort-006-823-789
NCGC00159522-02
NCGC00159522-03
Neokef
Neolexina
Noveol
Novolexin
Nufex
Oracef
Oriphex
Oroxin
Ortisporina
Ospexin
Palitrex
Panixine Disperdose
Panixine disperdose (TN)
Pectril
Prestwick0_000358
Prestwick1_000358
Prestwick2_000358
Prestwick3_000358
Prestwick_750
Prindex
Pyassan
Rilexine
Roceph
Roceph Distab
Rogevil
S 6437
SAM001246761
SMR000338536
SPBio_002376
SQ 20248
Sanaxin
Sartosona
Sencephalin
Sepexin
Servicef
Servispor
Sialexin
Sinthecillin
Sintolexyn
Sporicef
Sporidex
Syncl
Syncle
Synecl
Tepaxin
Theratrex
Tokiolexin
UNII-5SFF1W6677
UNII-OBN7UDS42Y
Uphalexin
Viosporine
Voxxim
Winlex
ZINC01530596
ZINC03830500
Zabytrex
Zozarine
cefalexin hydrate
cefalexin monohydrate
cefalexin.H2O
cephalexin
cephalexin.H2O
25
Bacitracinapproved, vet_approvedPhase 3401405-87-4439542, 10909430
Synonyms:
(4R)-4-[[(2S)-2-[[(4R)-2-[(1S,2S)-1-amino-2-methylbutyl]-4,5-dihydro-1,3-thiazole-4-carbonyl]amino]-4-methylpentanoyl]amino]-5-[[(2S,3S)-1-[[(3S,6R,9S,12R,15R,18R,21S)-3-(2-amino-2-oxoethyl)-18-(3-aminopropyl)-12-benzyl-15-[(2S)-butan-2-yl]-6-(carboxymethyl)-9-(1H-imidazol-5-ylmethyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclopentacos-21-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-5-oxopentanoic acid
(4R)-4-[[(2S)-2-[[2-(1-amino-2-methylbutyl)-4,5-dihydro-1,3-thiazole-4-carbonyl]amino]-4-methylpentanoyl]amino]-5-[[(2S,3S)-1-[[(3S,6R,9S,12R,15S,18R,21S)-3-(2-amino-2-oxoethyl)-18-(3-aminopropyl)-12-benzyl-15-[(2S)-butan-2-yl]-6-(carboxymethyl)-9-(1H-imidazol-5-ylmethyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclopentacos-21-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-5-oxopentanoic acid
11702_FLUKA
11702_SIGMA
22601-59-8
4-[[2-[[2-(1-amino-2-methylbutyl)-4,5-dihydro-1,3-thiazole-4-carbonyl]amino]-4-methylpentanoyl]amino]-5-[[1-[[3-(2-amino-2-oxoethyl)-18-(3-aminopropyl)-12-benzyl-15-butan-2-yl-6-(carboxymethyl)-9-(1H-imidazol-5-ylmethyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclopentacos-21-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-5-oxopentanoic acid
46084_RIEDEL
AB00513964
AC1L22YV
AC1O6F67
AC1O8Q0J
AC1Q6GKZ
Altracin
B0125_SIGMA
BPBio1_000878
BSPBio_000798
Baciguent
Baciquent
Bacitracin A
Bacitracin A1
Bacitracin A2a
Bacitracin a2a
C15482
 
CHEMBL1200558
CID10909430
CID6474109
CID65281
CID6714010
Citracin
EINECS 245-115-9
Fortracin
HMS1570H20
L-Asparagine, N-[[(4R)-2-[(1S,2S)-1-amino-2-methylbutyl]-4,5-dihydro-4-thiazolyl]carbonyl]-L-leucyl-D-.alpha.-glutamyl-L-isoleucyl-L-lysyl-D-ornithyl-L-isoleucyl-D-phenylalanyl-L-histidyl-D-.alpha.-as
LS-23608
MLS002695992
MolPort-003-926-019
NSC 45737
Prestwick1_000919
Prestwick2_000919
Prestwick3_000919
SMR001562136
SPBio_002987
Solu-Tracin 50
UNII-DDA3RRX0P7
bacitracin
n-{[2-(1-amino-2-methylbutyl)-4,5-dihydro-1,3-thiazol-4-yl]carbonyl}leucyl-|A-glutamyl-n-[3-(2-amino-2-oxoethyl)-18-(3-aminopropyl)-12-benzyl-15-(butan-2-yl)-6-(carboxymethyl)-9-(1h-imidazol-5-ylmethyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclopentacosan-21-yl]isoleucinamide
partyl-, (10.4)-lactam
26
Levofloxacinapproved, investigationalPhase 3236100986-85-4149096
Synonyms:
(−
(-)-(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid
(-)-(S)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyridol[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid hemihydrate
(-)-(S)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7Hpyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid hemihydrate
(-)-Ofloxacin
(3S)-(-)-9-Fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid
(3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
(R)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid
(R)-isomer
(S)-(-)-9-Fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzooxazine-6-carboxylic acid
(S)-(-)-Ofloxacin
(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid
(S)-Ofloxacin
)-Ofloxacin
100986-85-4
100986-86-5
28266_FLUKA
28266_SIGMA
AC-7593
AC1L3YF8
Aeroquin
Ambap100986-85-4
BRD-K09471561-001-06-7
BSPBio_002689
C07660
C18H20FN3O4
C18H20FN3O4.H2O
CCRIS 4073
CCRIS 4074
CHEMBL33
CID149096
CPD000466387
Cravit
Cravit (TN)
Cravit Ophthalmic
D08120
DB01137
DR 3354
DR-3355
DR-3355: L-isomer of ofloxacin
DR3355
Elequine
Floxacin
Floxel
Floxin
HMS1922J07
HMS2051G04
HMS2090O10
HMS2093E18
HR 355
HR-355
Iquix
KBio2_002199
KBio2_004767
KBio2_007335
KBio3_001909
 
KBioGR_001605
KBioSS_002199
L-Ofloxacin
L-ofloxacin
L0193
LEVAQUIN IN DEXTROSE 5% IN PLASTIC CONTAINER
LEVOFLOXACIN
LFX
LS-133260
LS-171761
LVX
Leroxacin
Lesacin
Levaquin
Levofloxacin
Levofloxacin (INN)
Levofloxacin [USAN:INN:JAN]
Levofloxacin hydrate
Levofloxacin tablet, suspension or intravenous
Levofloxacine
Levofloxacine [INN-French]
Levofloxacino
Levofloxacino [INN-Spanish]
Levofloxacinum
Levofloxacinum [INN-Latin]
Levokacin
Levox
Levoxacin
MLS000759524
MLS001165709
MLS001423977
MP-376
MolPort-002-885-835
Mosardal
NCGC00178529-01
Nofaxin
Ofloxacin
Ofloxacin S-(-)-form
Oftaquix
Quixin
R-Ofloxacin
RWJ 25213-097
RWJ-25213
Reskuin
S-(-)-Ofloxacin
S1940_Selleck
SAM001246758
SMR000466387
SPBio_001891
SPECTRUM1504260
Spectrum2_001676
Spectrum3_000995
Spectrum4_001123
Spectrum5_001438
Spectrum_001719
Tavanic
Volequin
d-Levofloxacin
27
Clindamycinapproved, vet_approvedPhase 317218323-44-929029
Synonyms:
13441-63-9
16669-21-9
18323-44-9
21462-39-5 (mono-hydrochloride)
24620-78-8
24696-19-3
58207-19-5
7(S)-Chloro-7-deoxylincomycin
7-CDL
7-Chloro-7-deoxylincomycin
7-Chlorolincomycin
7-Deoxy-7(S)-chlorolincomycin
AC1L1EGQ
AC1L1GLA
AC1L9JV8
AC1MHD7N
AC1MHE1M
AC1MHUOE
AC1MHX4G
AC1NWAKO
AC1O7ENS
AC1O7GED
AC1OFCIP
AC1OFCIV
AC1OFCJ1
AC1OFCJ7
AC1OIBYJ
AC1OIBYL
AC1OIBYN
AC1Q2V4O
Antirobe
BIDD:GT0418
BPBio1_000236
BRD-A23034328-003-03-4
BSPBio_000214
BSPBio_002049
C06914
C18H33ClN2O5S
CAS-21462-39-5
CHEBI:3745
CHEMBL187
CID2786
CID29029
CID3000512
CID3001928
CID3032758
CID3034218
CID446598
CID5702026
CID6602476
CID6604361
CID7048642
CID7048644
CID7048646
CID7048648
CID7276014
CID7276016
CID7276018
CID9812677
CLDM
CLINDA & IL-12
CLY
Chlolincocin
Chlorlincocin
Chlorodeoxylincomycin
Chlorolincomycin
Cleocin
Cleocin (TN)
Cleocin (tn)
Cleocin HCl
Cleocin Hcl
Cleocin Pediatric
Cleocin Phosphate
Cleocin T
Cleocin T Gel
Cleocin T Lotion
Cleocin T Topical Solution
 
Clinda-Derm
ClindaDerm
Clindagel
Clindamicina
Clindamicina [INN-Spanish]
Clindamycin
Clindamycin & Interleukin 12
Clindamycin & VRC3375
Clindamycin (USAN/INN)
Clindamycin Hcl
Clindamycin Hydrochloride
Clindamycin Phosphate
Clindamycin [USAN:BAN:INN]
Clindamycine
Clindamycine [French]
Clindamycine [INN-French]
Clindamycinum
Clindamycinum [INN-Latin]
Clindesse
Clindets
Clinimycin
D00277
DB01190
Dalacin
Dalacin C
Dalacin C Flavored Granules
Dalacin C Phosphate
Dalacin T Topical Solution
Dalacine
DivK1c_000464
EINECS 242-209-1
Evoclin
HMS2089A05
HMS2089N16
HSDB 3037
I06-0826
IDI1_000464
KBio1_000464
KBio2_000638
KBio2_003206
KBio2_005774
KBio3_001269
KBioGR_000844
KBioSS_000638
Klimicin
Klindan 300
LS-187128
LS-98131
MLS001183714
Methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-alpha-D-galacto-octopyranoside
MolPort-002-323-206
MolPort-002-964-479
NCGC00016752-01
NCGC00178843-01
NCGC00179636-01
NINDS_000464
Prestwick0_000137
Prestwick1_000137
Prestwick2_000137
Prestwick3_000137
ResiDerm A
SMP2_000295
SMR000677917
SPBio_000670
SPBio_002153
STK177246
STOCK1N-31150
Sobelin
Spectrum2_000885
Spectrum3_000355
Spectrum4_000292
Spectrum5_001525
Spectrum_000158
U 21251
U-21,251
U-21251
UNII-3U02EL437C
Zindaclin
clindamycin
28
OfloxacinapprovedPhase 323682419-36-14583
Synonyms:
( -)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)(1,4)benzoxazin-6-carbonsaeure
(+-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid
(+/-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperaz inyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid
(+/-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7- -oxo-7H-pyrido(1,2,3-de)- -1,4-benzoxazine-6-carboxylic acid
(+/-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid
(+/-)-Floxin
118120-51-7 (hydrochloride)
33703_FLUKA
33703_RIEDEL
8-Fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid
82419-36-1
83380-47-6
85344-55-4
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
AB00513820
AC-7616
AC1L1IHM
AKOS001033517
BB_SC-1252
BPBio1_000345
BRD-A24228527-001-05-9
BRN 3657947
BSPBio_000313
BSPBio_003117
Bactocin
C07321
C18H20FN3O4
CCRIS 5233
CHEBI:7731
CHEMBL4
CID4583
CPD000058192
D00453
DB01165
DEXTROFLOXACINE
DL 8280
DL-8280
DL-8280, HOE-280, Exocin, Flobacin, Floxin, Floxil, Monoflocet, Ofloxacin
Danoflox
DivK1c_000721
EU-0100904
Effexin
Exocin
Exocine
FLOXIN IN DEXTROSE 5%
FLOXIN IN DEXTROSE 5% IN PLASTIC CONTAINER
Flobacin
Flodemex
Flotavid
Flovid
Floxal
Floxil
Floxin
Floxin (TN)
Floxin otic
Floxstat
Fugacin
HMS1568P15
HMS1921H12
HMS2090F07
HMS2092B10
HMS502E03
HOE 280
Hoe-280
I06-0112
I06-0380
IDI1_000721
Inoflox
KBio1_000721
KBio2_001666
KBio2_004234
KBio2_006802
KBio3_002617
KBioGR_000667
KBioSS_001666
Kinflocin
Kinoxacin
LS-133259
Liflox
Lopac0_000904
Loxinter
MLS000028749
MLS001074203
Marfloxacin
Medofloxine
Mergexin
MolPort-000-422-241
MolPort-000-873-068
NCGC00015772-02
NCGC00015772-10
 
NCGC00094219-01
NCGC00094219-02
NCGC00094219-03
NCGC00094219-04
NCGC00094219-05
NCGC00094219-06
NCGC00178284-01
NCGC00178284-02
NINDS_000721
NSC727071
Novecin
Nufafloqo
O 8757
O-Flox
O8757_SIGMA
OFLX
OFX
ORF 18489
ORF-28489
Obide
Occidal
Ocuflox
Ofcin
Oflin
Oflocee
Oflocet
Oflocin
Oflodal
Oflodex
Oflodura
Oflox
Ofloxacin (JP15/USP/INN)
Ofloxacin Otic
Ofloxacin [USAN:BAN:INN:JAN]
Ofloxacin, (S)-Isomer
Ofloxacina
Ofloxacina [DCIT]
Ofloxacine
Ofloxacine [French]
Ofloxacino
Ofloxacino [Spanish]
Ofloxacinum
Ofloxacinum [Latin]
Ofloxin
Ofus
Onexacin
Operan
Oprea1_242882
Orocin
Otonil
Oxaldin
PT 01
Pharflox
Praxin
Prestwick0_000237
Prestwick1_000237
Prestwick2_000237
Prestwick3_000237
Puiritol
Qinolon
Qipro
Quinolon
Quotavil
Rilox
Ru-43280
S1463_Selleck
SAM002264629
SMR000058192
SPBio_001387
SPBio_002234
SPECTRUM1502044
STK256723
Sinflo
Spectrum2_001464
Spectrum3_001499
Spectrum4_000324
Spectrum5_001063
Spectrum_001186
Tabrin
Taravid
Tariflox
Tarivid
Telbit
Tructum
UNII-A4P49JAZ9H
Uro Tarivid
Viotisone
Visiren
WP-0405
XED
Zanocin
ofloxacin
29Angiotensin II Type 1 Receptor BlockersPhase 31091
30Angiotensin Receptor AntagonistsPhase 31191
31AngiotensinogenPhase 31177
32Antihypertensive AgentsPhase 34207
33
Angiotensin IIPhase 3117868521-88-0, 11128-99-765143, 172198
Synonyms:
1-8-Angiotensin I
1-L-Aspasaginyl-5-L-valyl angiotensin octapeptide
Ang II
Angiotensin 2
Angiotensin II (human)
 
Angiotensin II (mouse)
Angiotonin
Asp-arg-val-TYR-ile-his-pro-phe
Human angiotensin II
Hypertensin
Ile(5)-angiotensin II
34Rho(D) Immune GlobulinPhase 2, Phase 3326
35Pharmaceutical SolutionsPhase 2, Phase 38192
36gamma-GlobulinsPhase 2, Phase 3326
37AntibodiesPhase 2, Phase 36394
38Adrenergic beta-1 Receptor AntagonistsPhase 3364
39ImmunoglobulinsPhase 2, Phase 36394
40Immunoglobulins, IntravenousPhase 2, Phase 3333
41Renal AgentsPhase 3754
42PolymyxinsPhase 362
43Polymyxin BPhase 349
44Topoisomerase InhibitorsPhase 35069
45Antitubercular AgentsPhase 31343
46Antibiotics, AntitubercularPhase 37180
47Clindamycin phosphatePhase 3172
48Anti-Infective AgentsPhase 322062
49Anti-Bacterial AgentsPhase 311226
50Clindamycin palmitatePhase 3172

Interventional clinical trials:

(show top 50)    (show all 64)
idNameStatusNCT IDPhase
1Mode Evaluation in Sick Sinus Syndrome Trial (MODEST)Unknown statusNCT00161551Phase 4
2Efficacy of a Pacemaker Algorithm in Promotion of the Intrinsic Heart Activity.Unknown statusNCT00156741Phase 4
3Arrhythmia Restart Prevention and RatE STabilization in Atrial FibrillationUnknown statusNCT00224341Phase 4
4Antiarrhythmic Drugs Assessment in Preventing Atrial FibrillationUnknown statusNCT02145546Phase 4
5Pacing of the Atria in Sick Sinus Syndrome Trial Preventive Strategies for Atrial FibrillationCompletedNCT00161538Phase 4
6Beluga - Clinical Observations of Automatic Algorithms for Cardiac PacingCompletedNCT00286858Phase 4
7Austria Study - Analysis of Difference Between Active and Passive Fixation LeadsCompletedNCT00180557Phase 4
8Prevention of Atrial Arrhythmia in Patients Without Atrioventricular (AV) Conduction DiseaseCompletedNCT01170611Phase 4
9Medtronic Genetic Arrhythmia Markers for Early Detection (GAME Study)CompletedNCT00664807Phase 4
10DISCOVERY: Diagnostic Data and Genetic Polymorphisms in ICD Patients.CompletedNCT00478933Phase 4
11Falls and Cardiovascular Events in Pacemaker PatientsCompletedNCT01037426Phase 4
12PANORAMA Observational StudyCompletedNCT00382525Phase 4
13Spontaneous Atrio Ventricular Conduction PreservationCompletedNCT00655213Phase 4
14Syncope: Pacing or Recording in the Later YearsActive, not recruitingNCT01423994Phase 4
15Use of Amiodarone in Atrial Fibrillation Associated With Severe Sepsis or Septic ShockEnrolling by invitationNCT02668432Phase 4
16Virtual Clinic Pacemaker Follow-upTerminatedNCT00475124Phase 4
17Increasing Atrial Base Rate Pacing to Reduce Atrial FibrillationCompletedNCT02317068Phase 3
18Mode Selection Trial in Sinus Node Dysfunction (MOST)CompletedNCT00000561Phase 3
19Comparison of Two Medications Aimed at Slowing Aortic Root Enlargement in Individuals With Marfan Syndrome--Pediatric Heart NetworkCompletedNCT00429364Phase 3
20Phase 2/3 Study of IGSC, 20% in PIDDCompletedNCT01218438Phase 2, Phase 3
21Perioperative Antibiotic Therapy to Prevent Cardiac Implantable Electronic Device Infections.RecruitingNCT02809131Phase 3
22The Danish Multicenter Randomised Study on AAI Versus DDD Pacing in Sick Sinus SyndromeTerminatedNCT00236158Phase 2, Phase 3
23Left Ventricular Septum Pacing in Patients by Transvenous Approach Through the Inter-ventricular SeptumCompletedNCT01609738Phase 1, Phase 2
24Second Study on Cardio-neuromodulation in HumansRecruitingNCT02954666Phase 2
25Gulf War Illness Nasal Irrigation StudyActive, not recruitingNCT01700725Phase 2
26RV Septal Versus Minimized RV Pacing in Sick Sinus SyndromeUnknown statusNCT01477138
27The Role of Angiotensinogen Gene Polymorphism in the Pathogenesis of Non-familial Sick Sinus SyndromeUnknown statusNCT01310920
28The Effect of Losartan on Atrial Fibrillation (AF) Burden and Pacemaker Dependence in Patients With Sick Sinus SyndromeUnknown statusNCT00647257
29Left Ventricular Function and Remodelling During Permanent PacingUnknown statusNCT00228241
30Imaging Cardiac Electrical Remodeling With Electrocardiogram Imaging (ECGI)Unknown statusNCT00785564
31Left Ventricular Pacing to Prevent Iatrogenic TR Pilot StudyUnknown statusNCT02314897
32Identification of Gene Polymorphism in Patients With Sick Sinus Syndrome in Chinese Population in TaiwanUnknown statusNCT00314223
33Right Ventricular Lead Placement in a Pacemaker Population: Evaluation of Apical and Alternative PositionUnknown statusNCT01647490
34A Comparison of Rate Response Performance in Pacemaker Patients With an Indication of Sinus Node DysfunctionUnknown statusNCT02027909
35Minimizing Ventricular PacingUnknown statusNCT01611389
36Ventricular Pace Suppression Versus Intrinsic Rhythm Support StudyCompletedNCT01528657
37Right Ventricle (RV) Markers of Future Pacing Induced Ventricular Dysfunction - PilotCompletedNCT02198781
38The Atrial High Rate Episodes in Pacemaker PatientsCompletedNCT00627328
39Prospective Registry of Pacemaker Patients Concerning Percentage of Right Ventricular Pacing, LVEF and NYHA ClassCompletedNCT00292539
40SAVEPACe - Search AV Extension and Managed Ventricular Pacing for Promoting Atrio-Ventricular ConductionCompletedNCT00284830
41Natural Evolution of AV Conduction Disorders in Patients Implanted With Cardiac PacemakersCompletedNCT00531037
42To Pace or Not to Pace in Sinus Node DiseaseCompletedNCT02485093
43Right Ventricular Outflow Tract StudyCompletedNCT01294839
44Evaluation of Pacemaker Algorithms to Avoid Unnecessary Right Ventricular PacingCompletedNCT01803217
45Ingenio Device Algorithm StudyCompletedNCT01441583
46IES-ACap: Influence of Atrial Pulse Width in the Behaviour of ACap™ Confirm Algorithm.CompletedNCT00832260
47Real Life Automatic Atrial Capture Device ControlCompletedNCT02400983
48Reducing Atrial Pacing Rate to Reduce Atrial Fibrillation in Patients With Sick Sinus Syndrome.RecruitingNCT02034526
49Left Ventricular Pacing to Avoid Cardiac Enlargement StudyRecruitingNCT01302717
50Registry to Improve the Adoption of Consensus Treatment Guidelines (IMPROVE Brady)RecruitingNCT01643707

Search NIH Clinical Center for Sick Sinus Syndrome


Cochrane evidence based reviews: sick sinus syndrome

Genetic Tests for Sick Sinus Syndrome

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Genetic tests related to Sick Sinus Syndrome:

id Genetic test Affiliating Genes
1 Sick Sinus Syndrome27
2 Sinus Node Disease27

Anatomical Context for Sick Sinus Syndrome

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MalaCards organs/tissues related to Sick Sinus Syndrome:

36
Heart, Testes, Atrioventricular node, B cells, Lung, Brain, Spleen

Publications for Sick Sinus Syndrome

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Articles related to Sick Sinus Syndrome:

(show top 50)    (show all 530)
idTitleAuthorsYear
1
Short-term heart rate variability in dogs with sick sinus syndrome or chronic mitral valve disease as compared to healthy controls. (28525326)
2017
2
Persistent Sick Sinus Syndrome in Scrub Typhus. (28500798)
2017
3
SEVERE AMIODARONE-INDUCED BRADICARDIA CONCEALES SICK SINUS SYNDROME: CASE REPORT. (27125081)
2016
4
Outcome and survival in canine sick sinus syndrome and sinus node dysfunction: 93 cases (2002-2014). (27286907)
2016
5
Transforming Growth Factor-I^1 T869C Gene Polymorphism Is Associated with Acquired Sick Sinus Syndrome via Linking a Higher Serum Protein Level. (27380173)
2016
6
Genetic Variation of SCN5A in Korean Patients with Sick Sinus Syndrome. (26798387)
2016
7
G protein-gated IKACh channels as therapeutic targets for treatment of sick sinus syndrome and heart block. (26831068)
2016
8
Exome Sequencing Identifies a Novel LMNA Splice-Site Mutation and Multigenic Heterozygosity of Potential Modifiers in a Family with Sick Sinus Syndrome, Dilated Cardiomyopathy, and Sudden Cardiac Death. (27182706)
2016
9
Single lead atrial vs. dual chamber pacing in sick sinus syndrome: extended register-based follow-up in the DANPACE trial. (28039212)
2016
10
Autosomal recessive atrial disease presenting with sick sinus syndrome (SSS), right atrial fibrosis and biatrial dilatation: Clinical impact of genetic diagnosis. (26828384)
2016
11
Predictors of sick sinus syndrome in patients after successful radiofrequency catheter ablation of atrial flutter. (25510744)
2015
12
Beneficial effects of losartan for prevention of paroxysmal atrial fibrillation in patients with sick sinus syndrome: analysis with memory function of pacemaker. (25787020)
2015
13
Beware of Venous Anomalies in Young Patients with Sick Sinus Syndrome: A Report of Two Cases of Sick Sinus Syndrome with Systemic Venous Anomalies. (27326354)
2015
14
Development of Atrioventricular Block and Diagnostic Value of Stored Electrograms in Patients With Sick Sinus Syndrome and Implanted Pacemaker. (25753690)
2015
15
Anaplastic lymphoma kinase-positive lung adenocarcinoma patient with development of sick sinus syndrome while on targeted treatment with crizotinib. (25922742)
2015
16
Combined Algorithm Using a Poor Increase in Inferior P-Wave Amplitude During Sympathetic Stimulation and Sinus Node Recovery Time for the Diagnosis of Sick Sinus Syndrome. (26289967)
2015
17
Sodium Hydroxide Pinpoint Pressing Permeation Method for the Animal Modeling of Sick Sinus Syndrome. (26118592)
2015
18
Sick Sinus Syndrome. (26485000)
2015
19
Stored intracardiac electrograms reveal patients with sick sinus syndrome frequently develop atrioventricular block. (25947003)
2015
20
Novel Mutation in the I+-Myosin Heavy Chain Gene Is Associated With Sick Sinus Syndrome. (25717017)
2015
21
ECG of the Month. Third-degree AV block with sick sinus syndrome. (25835165)
2015
22
Effective Management of Atrioventricular Interval for Paroxysmal Atrial Fibrillation That Developed After DDDR Pacemaker Implantation in a Sick Sinus Syndrome Patient. (26370366)
2015
23
Elevated plasma norepinephrine level and sick sinus syndrome in patients with lone atrial fibrillation. (25968056)
2015
24
Red blood cell distribution width and atrial fibrillation in patients with sick sinus syndrome. (26321105)
2015
25
Dual-chamber pacemakers for treating symptomatic bradycardia due to sick sinus syndrome without atrioventricular block: a systematic review and economic evaluation. (26293406)
2015
26
Sick sinus syndrome and atrial fibrillation in older persons - A view from the sinoatrial nodal myocyte. (25668431)
2015
27
Role of temporary pacing at the right ventricular outflow tract in anesthetic management of a patient with asymptomatic sick sinus syndrome. (26712989)
2015
28
Sodium channelopathy underlying familial sick sinus syndrome with early onset and predominantly male characteristics. (24762805)
2014
29
Association of sick sinus syndrome with incident cardiovascular disease and mortality: the atherosclerosis risk in communities study and cardiovascular health study. (25285853)
2014
30
Sick sinus syndrome: synopsis. (25104520)
2014
31
Genetic analysis in a family affected by sick sinus syndrome may reduce the sudden death risk in a young aspiring competitive athlete. (24295898)
2014
32
Right versus left atrial pacing in patients with sick sinus syndrome and paroxysmal atrial fibrillation (Riverleft study): study protocol for randomized controlled trial. (25403703)
2014
33
The effectiveness of the atrial or atrio-ventricular stimulation for sick sinus syndrome in a long term observation. (25001847)
2014
34
Syncope in paced patients with sick sinus syndrome from the DANPACE trial: incidence, predictors and prognostic implication. (24711481)
2014
35
Isoprenaline: a potential contributor in sick sinus syndrome--insights from a mathematical model of the rabbit sinoatrial node. (24578642)
2014
36
Donepezil-associated sick sinus syndrome. (24515686)
2014
37
Sick sinus syndrome associated with hypopituitarism: a case report and literature review. (25332716)
2014
38
Health economic evaluation of single-lead atrial pacing vs. dual-chamber pacing in sick sinus syndrome. (24451290)
2014
39
A truncating SCN5A mutation combined with genetic variability causes sick sinus syndrome and early atrial fibrillation. (24582607)
2014
40
Familial sick sinus syndrome. (24172807)
2013
41
Autosomal recessive paediatric sick sinus syndrome associated with novel compound mutations in SCN5A. (23200271)
2013
42
CHADS2 and CHA2DS2-VASc score to assess risk of stroke and death in patients paced for sick sinus syndrome. (23539553)
2013
43
Sick sinus syndrome: a review. (23939447)
2013
44
Sick sinus syndrome: a family study. (24020943)
2013
45
Sick Sinus Syndrome in HCN1-Deficient Mice. (24218458)
2013
46
Efficacy of catheter ablation for atrial fibrillation in patients with a permanent pacemaker for sick sinus syndrome. (24126390)
2013
47
Symptomatic sick sinus syndrome requiring permanent pacemaker implantation in a patient uwith mirror image dextrocardia with situs inversus and infertility. (24000510)
2013
48
MOG1 rescues defective trafficking of Na(v)1.5 mutations in Brugada syndrome and sick sinus syndrome. (23420830)
2013
49
Left atrial responses to acute right ventricular apical pacing in patients with sick sinus syndrome. (23822568)
2013
50
A novel SCN5A mutation demonstrating a variety of clinical phenotypes in familial sick sinus syndrome. (23955615)
2013

Variations for Sick Sinus Syndrome

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Expression for genes affiliated with Sick Sinus Syndrome

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Search GEO for disease gene expression data for Sick Sinus Syndrome.

Pathways for genes affiliated with Sick Sinus Syndrome

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Pathways related to Sick Sinus Syndrome according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.9HCN4, SCN5A
29.8MYH6, SCN5A

GO Terms for genes affiliated with Sick Sinus Syndrome

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Cellular components related to Sick Sinus Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1caveolaGO:000590110.1RANGRF, SCN5A
2intercalated discGO:00147049.7RANGRF, SCN5A

Biological processes related to Sick Sinus Syndrome according to GeneCards Suite gene sharing:

(show all 13)
idNameGO IDScoreTop Affiliating Genes
1membrane depolarization during cardiac muscle cell action potentialGO:008601210.5HCN4, SCN5A
2membrane depolarization during SA node cell action potentialGO:008604610.5HCN4, SCN5A
3cardiac muscle contractionGO:006004810.4MYH6, SCN5A
4regulation of heart rate by cardiac conductionGO:008609110.3HCN4, SCN5A
5positive regulation of phosphatidylinositol 3-kinase signalingGO:001406810.2AGT, F2
6positive regulation of reactive oxygen species metabolic processGO:200037910.2AGT, F2
7regulation of cardiac muscle cell action potential involved in regulation of contractionGO:009890910.2HCN4, RANGRF
8regulation of postsynaptic membrane potentialGO:006007810.1HCN4, SCN5A
9regulation of membrane depolarizationGO:000325410.1HCN4, RANGRF
10embryonic forelimb morphogenesisGO:003511510.1SHOX2, TBX3
11SA node cell action potentialGO:00860159.9HCN4, SCN5A
12regulation of sodium ion transmembrane transportGO:19023059.8RANGRF, SCN5A
13regulation of heart rateGO:00020279.1AGT, HCN4, MYH6, RANGRF, SCN5A

Molecular functions related to Sick Sinus Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1sodium channel activityGO:000527210.3HCN4, SCN5A
2sodium channel regulator activityGO:001708010.0RANGRF, SCN5A
3voltage-gated sodium channel activityGO:00052489.9HCN4, SCN5A

Sources for Sick Sinus Syndrome

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet