MCID: SLN001
MIFTS: 32

Silent Myocardial Infarction malady

Categories: Cardiovascular diseases

Aliases & Classifications for Silent Myocardial Infarction

Aliases & Descriptions for Silent Myocardial Infarction:

Name: Silent Myocardial Infarction 12 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:5854
NCIt 47 C35400
SNOMED-CT 64 194796000 233843008
UMLS 69 C0340324

Summaries for Silent Myocardial Infarction

MalaCards based summary : Silent Myocardial Infarction is related to myocardial infarction and myositis fibrosa. An important gene associated with Silent Myocardial Infarction is AGTR1 (Angiotensin II Receptor Type 1), and among its related pathways/superpathways are TRAF Pathway and Signaling events mediated by VEGFR1 and VEGFR2. The drugs Nitric Oxide and Aspirin have been mentioned in the context of this disorder. Affiliated tissues include lung and heart.

Related Diseases for Silent Myocardial Infarction

Graphical network of the top 20 diseases related to Silent Myocardial Infarction:



Diseases related to Silent Myocardial Infarction

Symptoms & Phenotypes for Silent Myocardial Infarction

Drugs & Therapeutics for Silent Myocardial Infarction

Drugs for Silent Myocardial Infarction (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 99)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Nitric Oxide Approved Phase 4 10102-43-9 145068
2
Aspirin Approved, Vet_approved Phase 4 50-78-2 2244
3
Metoprolol Approved, Investigational Phase 4 37350-58-6, 51384-51-1 4171
4
Nebivolol Approved, Investigational Phase 4 152520-56-4, 99200-09-6, 118457-14-0 71301
5
Ticlopidine Approved Phase 4,Phase 3 55142-85-3 5472
6
Ticagrelor Approved Phase 4,Phase 3 274693-27-5 9871419
7
Nitrous oxide Approved, Vet_approved Phase 4 10024-97-2 948
8
Verapamil Approved Phase 4 52-53-9 2520
9
Miconazole Approved, Investigational, Vet_approved Phase 4 22916-47-8 4189
10
Everolimus Approved Phase 4 159351-69-6 6442177
11
Sirolimus Approved, Investigational Phase 4 53123-88-9 5284616 6436030 46835353
12
Glyburide Approved Phase 4 10238-21-8 3488
13
Pioglitazone Approved, Investigational Phase 4 111025-46-8 4829
14
Gliclazide Approved Phase 4 21187-98-4 3475
15
Glimepiride Approved Phase 4,Phase 3 93479-97-1 3476
16
Metformin Approved Phase 4 657-24-9 14219 4091
17
Salicylic acid Approved, Vet_approved Phase 4 69-72-7 338
18
Tacrolimus Approved, Investigational Phase 4 104987-11-3 445643 439492
19
Clopidogrel Approved, Nutraceutical Phase 4,Phase 3 120202-66-6, 113665-84-2 60606
20
Cobalt Phase 4 7440-48-4 104729
21
Chromium Phase 4 7440-47-3 27668
22 Trace Elements Phase 4
23 Micronutrients Phase 4
24 Analgesics Phase 4
25 Adrenergic Agents Phase 4
26 Adrenergic Agonists Phase 4
27 Adrenergic Antagonists Phase 4
28 Adrenergic beta-1 Receptor Antagonists Phase 4
29 Adrenergic beta-Agonists Phase 4
30 Neurotransmitter Agents Phase 4,Phase 3
31 Adrenergic beta-Antagonists Phase 4
32 Sympatholytics Phase 4
33 Cyclooxygenase Inhibitors Phase 4
34 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 3
35 Analgesics, Non-Narcotic Phase 4
36 Anesthetics Phase 4
37 Anesthetics, General Phase 4
38 Anesthetics, Inhalation Phase 4
39 Peripheral Nervous System Agents Phase 4
40 Vasodilator Agents Phase 4
41 Endothelium-Dependent Relaxing Factors Phase 4
42 Anti-Arrhythmia Agents Phase 4,Phase 3
43 Hypoglycemic Agents Phase 4,Phase 3
44 Platelet Aggregation Inhibitors Phase 4,Phase 3
45 Fibrinolytic Agents Phase 4,Phase 3
46 Anti-Inflammatory Agents Phase 4
47 Antihypertensive Agents Phase 4
48 Purinergic P2 Receptor Antagonists Phase 4,Phase 3
49 Purinergic P2Y Receptor Antagonists Phase 4,Phase 3
50 Anti-Inflammatory Agents, Non-Steroidal Phase 4

Interventional clinical trials:

(show all 35)
id Name Status NCT ID Phase
1 Comparative Phase IV Study: Efficacy And Safety of TiTAN2 Versus COBALT-CHROME Stents- EVIDENCEII Unknown status NCT01918150 Phase 4
2 The ENIGMA II Trial:Nitrous Oxide Anaesthesia and Cardiac Morbidity After Major Surgery: a Randomised Controlled Trial Completed NCT00430989 Phase 4
3 The Effect of Nebivolol on Endothelial Dysfunction in African Americans With Hypertension Completed NCT01049009 Phase 4
4 Harmonizing Optimal Strategy for Treatment of Coronary Artery Stenosis - Coronary Intervention With Next Generation Drug-Eluting Stent Platforms and Abbreviated Dual Antiplatelet Therapy (HOST-IDEA) Trial Recruiting NCT02601157 Phase 4
5 Prevention of Silent Cerebral Thromboembolism by Oral Anticoagulation With Dabigatran After Pulmonary Vein Isolation for Atrial Fibrillation Recruiting NCT02067182 Phase 4
6 Thiazolidinediones Or Sulphonylureas and Cardiovascular Accidents.Intervention Trial Active, not recruiting NCT00700856 Phase 4
7 Efficacy and Safety of New Generation Drug Eluting Stents Associated With an Ultra Short Duration of Dual Antiplatelet Therapy. Design of the Short Duration of Dual antiplatElet Therapy With SyNergy II Stent in Patients Older Than 75 Years Undergoing Perc Active, not recruiting NCT02099617 Phase 4
8 PROMUS Element Plus US Post-Approval Study Active, not recruiting NCT01589978 Phase 4
9 SILENT - Subclinical AtrIal FibrilLation and StrokE PreveNtion Trial Not yet recruiting NCT02004509 Phase 4
10 Brazilian and Italian Evaluation of Safety Using Tacrolimus-eluting Stent With Short-term Dual Antiplatelet Regimen Terminated NCT01122719 Phase 4
11 International Randomized Comparison Between DES Limus Carbostent and Taxus Drug Eluting Stents in the Treatment of De-novo Coronary Lesions Unknown status NCT01373502 Phase 3
12 BI 10773 (Empagliflozin) Cardiovascular Outcome Event Trial in Type 2 Diabetes Mellitus Patients (EMPA-REG OUTCOME). Completed NCT01131676 Phase 3
13 A Comparison of Ticagrelor (AZD6140) and Clopidogrel in Patients With Acute Coronary Syndrome Completed NCT00391872 Phase 3
14 Sonolysis in Risk Reduction of Symptomatic and Silent Brain Infarctions During Coronary Stenting Recruiting NCT02351050 Phase 3
15 CAROLINA: Cardiovascular Outcome Study of Linagliptin Versus Glimepiride in Patients With Type 2 Diabetes Active, not recruiting NCT01243424 Phase 3
16 Second Generation" Drug-Eluting Stents Implantation Followed by Six Versus Twelve-Month - Dual Antiplatelet Therapy Terminated NCT00944333 Phase 3
17 Pilot Study of Atorvastatin for Orthopedic Surgery Patients Completed NCT02197065 Phase 2
18 Feasibility Study of Photopheresis Post Angioplasty Terminated NCT00157001 Phase 2
19 Pain Perception is Attenuated in Patients With Painless Myocardial Infarction Completed NCT00192790
20 Comparison of Anti-Ischemic Drug Therapy and Percutaneous Transluminal Angioplasty After Myocardial Infarction Completed NCT00387231
21 Detection of Ischemia in Asymptomatic Diabetics Completed NCT00769275
22 Study to Investigate Effects of Antiischemic Drug Therapy in Silent Ischemia Completed NCT00382421
23 The Effect of Exercise Training on Mental Stress-Induced Silent Ischemia Completed NCT00018252
24 Multicenter Study of Silent Myocardial Ischemia (MSSMI) Completed NCT00005216
25 The Silent Cortical Infarcts in the Cerebral Amyloid Angiopathy: Is There a Link With Subarachnoid Hemorrhage? Completed NCT02837354
26 MYOCARDIAL SILENT INFARCTIONS AND FIBROSIS IN FAMILIAL HYPERCHOLESTEROLEMIA (CHOLCOEUR) Recruiting NCT02517944
27 Imaging Silent Brain Infarct And Thrombosis in Acute Myocardial Infarction Recruiting NCT02917213
28 Detection no Invasive of a Silent Myocardial Ischemia Recruiting NCT02885428
29 SONOlysis in Prevention of Brain InfaRctions During Internal Carotid Endarterectomy Recruiting NCT02398734
30 Visualization of Asymptomatic Atherosclerotic Disease for Optimum Cardiovascular Prevention Active, not recruiting NCT01849575
31 A Randomized Clinical Evaluation of the BioFreedomâ„¢ Stent Active, not recruiting NCT01623180
32 Trial of MiStent Compared to Xience in Japan Active, not recruiting NCT02972671
33 Early Versus Late Initiation of Direct Oral Anticoagulants in Post-ischaemic Stroke Patients With Atrial fibrillatioN (ELAN): an International, Multicentre, Randomised-controlled, Two-arm, Assessor-blinded Trial Not yet recruiting NCT03148457
34 Do You Need to Assess Myocardial Ischemia in Type 2 Diabetes Terminated NCT00627783
35 Does Ranolazine Decrease Biomarkers of Myocardial Damage in Diabetics Withdrawn NCT02611596

Search NIH Clinical Center for Silent Myocardial Infarction

Genetic Tests for Silent Myocardial Infarction

Anatomical Context for Silent Myocardial Infarction

MalaCards organs/tissues related to Silent Myocardial Infarction:

39
Lung, Heart

Publications for Silent Myocardial Infarction

Articles related to Silent Myocardial Infarction:

(show top 50) (show all 65)
id Title Authors Year
1
Race and Sex Differences in the Incidence and Prognostic Significance of Silent Myocardial Infarction in the Atherosclerosis Risk in Communities (ARIC) Study. ( 27185168 )
2016
2
Erratum to: Association of cardiovascular disease risk factors with left ventricular mass, biventricular function, and the presence of silent myocardial infarction on cardiac MRI in an asymptomatic population. ( 27376356 )
2016
3
A Novel and Practical Screening Tool for the Detection of Silent Myocardial Infarction in Patients With Type 2 Diabetes. ( 27300573 )
2016
4
Association of cardiovascular disease risk factors with left ventricular mass, biventricular function, and the presence of silent myocardial infarction on cardiac MRI in an asymptomatic population. ( 27209284 )
2016
5
Silent myocardial infarction secondary to cardiac autonomic neuropathy in a patient with rheumatoid arthritis. ( 27489064 )
2016
6
Sudden death associated with silent myocardial infarction in a 35-year-old man: a case report. ( 26925778 )
2016
7
Silent myocardial infarction and stroke: findings of multimodality imaging. ( 25514927 )
2015
8
A rare long-term survival of the life-threatening trio: silent myocardial infarction complicated by ventricular septal rupture, type 2 diabetes mellitus and chronic bronchitis. ( 26543616 )
2015
9
A new cause of silent myocardial infarction: Bonsai. ( 25550251 )
2015
10
A silent myocardial infarction in the diabetes outpatient clinic: case report and review of the literature. ( 24616778 )
2013
11
Prevalence, extent, and independent predictors of silent myocardial infarction. ( 23597799 )
2013
12
Prognostic significance of silent myocardial infarction in newly diagnosed type 2 diabetes mellitus: United Kingdom Prospective Diabetes Study (UKPDS) 79. ( 23362315 )
2013
13
Silent myocardial infarction during hypoglycemic coma. ( 22276266 )
2012
14
Is silent myocardial infarction more common in women with type 2 diabetes than in men? ( 22446034 )
2012
15
An unusual case of left ventricular free wall rupture caused by a silent myocardial infarction. ( 23170099 )
2012
16
Prevalence, incidence, predictive factors and prognosis of silent myocardial infarction: a review of the literature. ( 21497307 )
2011
17
Silent myocardial infarction subsequent to cutaneous polyarteritis nodosa in a patient with positive lupus anticoagulant. ( 21763578 )
2011
18
Coronary aneurysm and silent myocardial infarction in an adolescent secondary to undiagnosed childhood Kawasaki disease. ( 20664770 )
2010
19
Incidence and predictors of silent myocardial infarction in type 2 diabetes and the effect of fenofibrate: an analysis from the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study. ( 19797259 )
2010
20
Does silent myocardial infarction add prognostic value in ST-elevation myocardial infarction patients without a history of prior myocardial infarction? Insights from the Assessment of Pexelizumab in Acute Myocardial Infarction (APEX-AMI) Trial. ( 20934561 )
2010
21
Silent myocardial infarction: the risk beyond the first admission. ( 20813725 )
2010
22
Cerebral transient ischemic attack due to left ventricular thrombus formation in a young patient with silent myocardial infarction and normal coronary arteries. ( 18160151 )
2009
23
Giant left ventricular aneurysm and intraventricular septal defect after silent myocardial infarction. ( 19329416 )
2009
24
Silent myocardial infarction in women with type II diabetes mellitus and microalbuminuria. ( 19209251 )
2008
25
The impact of remote patient monitoring in managing silent myocardial infarction in a residential home setting. ( 17584720 )
2007
26
Paradoxical mesentery embolism and silent myocardial infarction in primary antiphospholipid syndrome: a case report. ( 16543157 )
2006
27
Giant left-ventricular pseudoaneurysm following silent myocardial infarction. ( 16428885 )
2006
28
Unruptured giant left ventricular pseudoaneurysm complicating silent myocardial infarction in a diabetic young adult: left ventricular giant pseudoaneurysm after silent myocardial infarction. ( 16015433 )
2005
29
Silent myocardial infarction and its prognosis in a community-based cohort of Type 2 diabetic patients: the Fremantle Diabetes Study. ( 14963648 )
2004
30
Small vessel vasculitis with pulmonary aneurysms and silent myocardial infarction. ( 12869681 )
2003
31
Detection of a silent myocardial infarction with phosphor-31 two-dimensional chemical shift imaging (31P 2-D CSI). ( 12928747 )
2003
32
Silent myocardial infarction in women with impaired glucose tolerance: the Northern Sweden MONICA study. ( 14498994 )
2003
33
Silent myocardial infarction in Wegener's granulomatosis. ( 8612034 )
1996
34
Silent myocardial infarction during hypoglycaemic coma. ( 8894868 )
1996
35
Silent myocardial infarction in Wegener's granulomatosis. ( 7748024 )
1995
36
Infection of left ventricular thrombus in a patient with silent myocardial infarction--a unique complication. ( 8375427 )
1993
37
[Silent myocardial infarction caused by acute carbon monoxide poisoning]. ( 8405820 )
1993
38
Silent myocardial infarction. ( 2320516 )
1990
39
Silent myocardial infarction complicated by asymptomatic ventricular septal defect and deferred rupture of left ventricular pseudoaneurysm. ( 15227401 )
1990
40
Myocardial abscess after silent myocardial infarction. ( 2658198 )
1989
41
Silent myocardial infarction discovered during indium-111 white blood cell imaging. ( 3383524 )
1988
42
Utility of echocardiography in diagnosis of ventricular septal rupture following electrocardiographically silent myocardial infarction. ( 3450564 )
1987
43
Silent myocardial infarction and diabetic cardiovascular autonomic neuropathy. ( 3778054 )
1986
44
Complete AV heart block during acute silent myocardial infarction detected only by myocardial perfusion scintigraphy. ( 4048796 )
1985
45
Silent myocardial infarction in the elderly. ( 6473293 )
1984
46
Silent myocardial infarction in the diabetic population. ( 6711568 )
1984
47
Coincidence of cerebrovascular accident and silent myocardial infarction. ( 6215869 )
1982
48
Gallium-67 uptake in silent myocardial infarction: a case report. ( 693859 )
1978
49
SILENT MYOCARDIAL INFARCTION WITH POSTERIOR INFERIOR PSEUDOANEURYSM OF THE LEFT VENTRICLE PRESENTING AS A POSTERIOR LUNG MASS. ( 15216055 )
1978
50
Silent mitral regurgitation complicating silent myocardial infarction: hemodynamic and morphologic documentation. ( 5050232 )
1972

Variations for Silent Myocardial Infarction

Expression for Silent Myocardial Infarction

Search GEO for disease gene expression data for Silent Myocardial Infarction.

Pathways for Silent Myocardial Infarction

GO Terms for Silent Myocardial Infarction

Biological processes related to Silent Myocardial Infarction according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 positive regulation of MAPK cascade GO:0043410 9.4 FLT4 KDR
2 vascular endothelial growth factor receptor signaling pathway GO:0048010 9.37 FLT4 KDR
3 positive regulation of endothelial cell proliferation GO:0001938 9.32 FLT4 KDR
4 vasculogenesis GO:0001570 9.26 KDR TNNI3
5 positive regulation of endothelial cell migration GO:0010595 9.16 FLT4 KDR
6 cellular response to vascular endothelial growth factor stimulus GO:0035924 8.96 FLT4 KDR
7 vascular endothelial growth factor signaling pathway GO:0038084 8.62 FLT4 KDR

Molecular functions related to Silent Myocardial Infarction according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 integrin binding GO:0005178 9.26 KDR NISCH
2 transmembrane receptor protein tyrosine kinase activity GO:0004714 9.16 FLT4 KDR
3 growth factor binding GO:0019838 8.96 FLT4 KDR
4 vascular endothelial growth factor-activated receptor activity GO:0005021 8.62 FLT4 KDR

Sources for Silent Myocardial Infarction

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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