MCID: SLN001
MIFTS: 28

Silent Myocardial Infarction

Categories: Cardiovascular diseases

Aliases & Classifications for Silent Myocardial Infarction

MalaCards integrated aliases for Silent Myocardial Infarction:

Name: Silent Myocardial Infarction 12 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:5854
NCIt 46 C35400
SNOMED-CT 64 194796000 233843008
UMLS 69 C0340324

Summaries for Silent Myocardial Infarction

MalaCards based summary : Silent Myocardial Infarction is related to myocardial infarction and diabetes mellitus. An important gene associated with Silent Myocardial Infarction is TRPV1 (Transient Receptor Potential Cation Channel Subfamily V Member 1). The drugs Chromium and Nitrous oxide have been mentioned in the context of this disorder. Affiliated tissues include heart, lung and kidney.

Related Diseases for Silent Myocardial Infarction

Diseases related to Silent Myocardial Infarction via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 25)
# Related Disease Score Top Affiliating Genes
1 myocardial infarction 10.7
2 diabetes mellitus 10.1
3 aneurysm 10.0
4 autonomic neuropathy 9.9
5 neuropathy 9.9
6 atrial standstill 1 9.8
7 blood group, i system 9.8
8 rheumatoid arthritis 9.8
9 kawasaki disease 9.8
10 polyarteritis nodosa, childhood-onset 9.8
11 acute myocardial infarction 9.8
12 arthritis 9.8
13 chronic kidney failure 9.8
14 hypoglycemic coma 9.8
15 ventricular septal defect 9.8
16 antiphospholipid syndrome 9.8
17 coronary aneurysm 9.8
18 cerebritis 9.8
19 kidney disease 9.8
20 bronchitis 9.8
21 vasculitis 9.8
22 dextrocardia 9.8
23 polyarteritis nodosa 9.8
24 cutaneous polyarteritis nodosa 9.8
25 arteries, anomalies of 9.6 AGTR1 TRPV1

Graphical network of the top 20 diseases related to Silent Myocardial Infarction:



Diseases related to Silent Myocardial Infarction

Symptoms & Phenotypes for Silent Myocardial Infarction

Drugs & Therapeutics for Silent Myocardial Infarction

Drugs for Silent Myocardial Infarction (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 30)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Chromium Approved Phase 4 7440-47-3 27668
2
Nitrous oxide Approved, Vet_approved Phase 4 10024-97-2 948
3
Glyburide Approved Phase 4 10238-21-8 3488
4
Pioglitazone Approved, Investigational Phase 4 111025-46-8 4829
5
Gliclazide Approved Phase 4 21187-98-4 3475
6
Glimepiride Approved Phase 4,Phase 3 93479-97-1 3476
7
Metformin Approved Phase 4 657-24-9 4091 14219
8
2,4-thiazolidinedione Investigational Phase 4 2295-31-0
9
Cobalt Phase 4 7440-48-4 104729
10 Micronutrients Phase 4
11 Trace Elements Phase 4
12 Analgesics Phase 4
13 Central Nervous System Depressants Phase 4
14 Analgesics, Non-Narcotic Phase 4
15 Anesthetics Phase 4
16 Anesthetics, General Phase 4
17 Anesthetics, Inhalation Phase 4
18 Peripheral Nervous System Agents Phase 4
19 Hypoglycemic Agents Phase 4,Phase 3
20
Empagliflozin Approved Phase 3 864070-44-0
21
Linagliptin Approved Phase 3 668270-12-0 10096344
22
protease inhibitors Phase 3
23 HIV Protease Inhibitors Phase 3
24 Hormone Antagonists Phase 3
25 Hormones Phase 3
26 Dipeptidyl-Peptidase IV Inhibitors Phase 3
27 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3
28 Anti-Arrhythmia Agents Phase 3
29 Immunosuppressive Agents Phase 3
30 Incretins Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Comparative Phase IV Study: Efficacy And Safety of TiTAN2 Versus COBALT-CHROME Stents- EVIDENCEII Unknown status NCT01918150 Phase 4
2 The ENIGMA II Trial:Nitrous Oxide Anaesthesia and Cardiac Morbidity After Major Surgery: a Randomised Controlled Trial Completed NCT00430989 Phase 4 Nitrous Oxide;Nitrous Oxide
3 Thiazolidinediones Or Sulphonylureas and Cardiovascular Accidents.Intervention Trial Active, not recruiting NCT00700856 Phase 4 add-on pioglitazone;add-on sulphonylurea
4 BI 10773 (Empagliflozin) Cardiovascular Outcome Event Trial in Type 2 Diabetes Mellitus Patients (EMPA-REG OUTCOME). Completed NCT01131676 Phase 3 BI 10773 low dose;Placebo BI 10773 high dose;BI 10773 high dose;Placebo BI 10773 low dose;Placebo BI 10773 low dose;Placebo BI 10773 high dose
5 CAROLINA: Cardiovascular Outcome Study of Linagliptin Versus Glimepiride in Patients With Type 2 Diabetes Active, not recruiting NCT01243424 Phase 3 linagliptin;glimepiride;linagliptin placebo;glimepride placebo
6 MYOCARDIAL SILENT INFARCTIONS AND FIBROSIS IN FAMILIAL HYPERCHOLESTEROLEMIA (CHOLCOEUR) Unknown status NCT02517944
7 Pain Perception is Attenuated in Patients With Painless Myocardial Infarction Completed NCT00192790
8 Microparticles in Obstructive Sleep Apnea Recruiting NCT03438149

Search NIH Clinical Center for Silent Myocardial Infarction

Genetic Tests for Silent Myocardial Infarction

Anatomical Context for Silent Myocardial Infarction

MalaCards organs/tissues related to Silent Myocardial Infarction:

38
Heart, Lung, Kidney

Publications for Silent Myocardial Infarction

Articles related to Silent Myocardial Infarction:

(show top 50) (show all 70)
# Title Authors Year
1
Silent Myocardial Infarction: Listen to the Evidence. ( 29301632 )
2018
2
Acute coronary syndromes: Silent myocardial infarction increases the risk of heart failure. ( 29368702 )
2018
3
Silent Myocardial Infarction and Long-Term Risk of Heart Failure: The ARIC Study. ( 29301615 )
2018
4
Prognostic value of silent myocardial infarction in patients with chronic kidney disease being evaluated for kidney transplantation. ( 28958755 )
2017
5
Electrocardiographic QRS-T angle and the risk of incident silent myocardial infarction in the Atherosclerosis Risk in Communities study. ( 28515002 )
2017
6
Woven coronary anomaly leading to silent myocardial infarction: A case report. ( 29095260 )
2017
7
Silent myocardial infarction secondary to cardiac autonomic neuropathy in a patient with rheumatoid arthritis. ( 27489064 )
2016
8
Race and Sex Differences in the Incidence and Prognostic Significance of Silent Myocardial Infarction in the Atherosclerosis Risk in Communities (ARIC) Study. ( 27185168 )
2016
9
Association of cardiovascular disease risk factors with left ventricular mass, biventricular function, and the presence of silent myocardial infarction on cardiac MRI in an asymptomatic population. ( 27209284 )
2016
10
A Novel and Practical Screening Tool for the Detection of Silent Myocardial Infarction in Patients With Type 2 Diabetes. ( 27300573 )
2016
11
Sudden death associated with silent myocardial infarction in a 35-year-old man: a case report. ( 26925778 )
2016
12
A rare long-term survival of the life-threatening trio: silent myocardial infarction complicated by ventricular septal rupture, type 2 diabetes mellitus and chronic bronchitis. ( 26543616 )
2015
13
A new cause of silent myocardial infarction: Bonsai. ( 25550251 )
2015
14
Silent myocardial infarction and stroke: findings of multimodality imaging. ( 25514927 )
2015
15
Prognostic significance of silent myocardial infarction in newly diagnosed type 2 diabetes mellitus: United Kingdom Prospective Diabetes Study (UKPDS) 79. ( 23362315 )
2013
16
Prevalence, extent, and independent predictors of silent myocardial infarction. ( 23597799 )
2013
17
A silent myocardial infarction in the diabetes outpatient clinic: case report and review of the literature. ( 24616778 )
2013
18
Silent myocardial infarction during hypoglycemic coma. ( 22276266 )
2012
19
An unusual case of left ventricular free wall rupture caused by a silent myocardial infarction. ( 23170099 )
2012
20
Is silent myocardial infarction more common in women with type 2 diabetes than in men? ( 22446034 )
2012
21
Prevalence, incidence, predictive factors and prognosis of silent myocardial infarction: a review of the literature. ( 21497307 )
2011
22
Silent myocardial infarction subsequent to cutaneous polyarteritis nodosa in a patient with positive lupus anticoagulant. ( 21763578 )
2011
23
Does silent myocardial infarction add prognostic value in ST-elevation myocardial infarction patients without a history of prior myocardial infarction? Insights from the Assessment of Pexelizumab in Acute Myocardial Infarction (APEX-AMI) Trial. ( 20934561 )
2010
24
Silent myocardial infarction: the risk beyond the first admission. ( 20813725 )
2010
25
Incidence and predictors of silent myocardial infarction in type 2 diabetes and the effect of fenofibrate: an analysis from the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study. ( 19797259 )
2010
26
Coronary aneurysm and silent myocardial infarction in an adolescent secondary to undiagnosed childhood Kawasaki disease. ( 20664770 )
2010
27
Cerebral transient ischemic attack due to left ventricular thrombus formation in a young patient with silent myocardial infarction and normal coronary arteries. ( 18160151 )
2009
28
Giant left ventricular aneurysm and intraventricular septal defect after silent myocardial infarction. ( 19329416 )
2009
29
Silent myocardial infarction in women with type II diabetes mellitus and microalbuminuria. ( 19209251 )
2008
30
The impact of remote patient monitoring in managing silent myocardial infarction in a residential home setting. ( 17584720 )
2007
31
Giant left-ventricular pseudoaneurysm following silent myocardial infarction. ( 16428885 )
2006
32
Paradoxical mesentery embolism and silent myocardial infarction in primary antiphospholipid syndrome: a case report. ( 16543157 )
2006
33
Unruptured giant left ventricular pseudoaneurysm complicating silent myocardial infarction in a diabetic young adult: left ventricular giant pseudoaneurysm after silent myocardial infarction. ( 16015433 )
2005
34
Silent myocardial infarction and its prognosis in a community-based cohort of Type 2 diabetic patients: the Fremantle Diabetes Study. ( 14963648 )
2004
35
Small vessel vasculitis with pulmonary aneurysms and silent myocardial infarction. ( 12869681 )
2003
36
Silent myocardial infarction in women with impaired glucose tolerance: the Northern Sweden MONICA study. ( 14498994 )
2003
37
Detection of a silent myocardial infarction with phosphor-31 two-dimensional chemical shift imaging (31P 2-D CSI). ( 12928747 )
2003
38
Silent myocardial infarction during hypoglycaemic coma. ( 8894868 )
1996
39
Silent myocardial infarction in Wegener's granulomatosis. ( 8612034 )
1996
40
Silent myocardial infarction in Wegener's granulomatosis. ( 7748024 )
1995
41
[Silent myocardial infarction caused by acute carbon monoxide poisoning]. ( 8405820 )
1993
42
Infection of left ventricular thrombus in a patient with silent myocardial infarction--a unique complication. ( 8375427 )
1993
43
Silent myocardial infarction complicated by asymptomatic ventricular septal defect and deferred rupture of left ventricular pseudoaneurysm. ( 15227401 )
1990
44
Silent myocardial infarction. ( 2320516 )
1990
45
Myocardial abscess after silent myocardial infarction. ( 2658198 )
1989
46
Silent myocardial infarction discovered during indium-111 white blood cell imaging. ( 3383524 )
1988
47
Utility of echocardiography in diagnosis of ventricular septal rupture following electrocardiographically silent myocardial infarction. ( 3450564 )
1987
48
Silent myocardial infarction and diabetic cardiovascular autonomic neuropathy. ( 3778054 )
1986
49
Complete AV heart block during acute silent myocardial infarction detected only by myocardial perfusion scintigraphy. ( 4048796 )
1985
50
Silent myocardial infarction in the elderly. ( 6473293 )
1984

Variations for Silent Myocardial Infarction

Expression for Silent Myocardial Infarction

Search GEO for disease gene expression data for Silent Myocardial Infarction.

Pathways for Silent Myocardial Infarction

GO Terms for Silent Myocardial Infarction

Biological processes related to Silent Myocardial Infarction according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of cytosolic calcium ion concentration GO:0007204 9.16 AGTR1 TRPV1
2 protein homotetramerization GO:0051289 8.96 GLS TRPV1
3 glutamate secretion GO:0014047 8.62 GLS TRPV1

Molecular functions related to Silent Myocardial Infarction according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 phosphatidylinositol binding GO:0035091 8.62 NISCH TRPV1

Sources for Silent Myocardial Infarction

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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