MCID: SLN001
MIFTS: 26

Silent Myocardial Infarction malady

Summaries for Silent Myocardial Infarction

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33MalaCards
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MalaCards: Silent Myocardial Infarction is related to acute myocardial infarction and septal myocardial infarction. An important gene associated with Silent Myocardial Infarction is INS (insulin), and among its related pathways are Regulation of Actin Cytoskeleton and Glioma. The compounds gemfibrozil and bezafibrate have been mentioned in the context of this disorder. Affiliated tissues include lung and heart.

Aliases & Classifications for Silent Myocardial Infarction

Sources:
8Disease Ontology, 61UMLS, 40NCIt, 57SNOMED-CT
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Aliases & Descriptions:

silent myocardial infarction 8 61


External Ids:

Disease Ontology8 DOID:5854
NCIt40 C35400

Related Diseases for Silent Myocardial Infarction

Sources:
17GeneCards, 18GeneDecks
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Diseases related to Silent Myocardial Infarction via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 46)
idRelated DiseaseScoreTop Affiliating Genes
1acute myocardial infarction30.6PIK3C2A
2septal myocardial infarction10.4
3wegener's granulomatosis10.3
4ventricular septal defect10.3
5antiphospholipid syndrome10.2
6hypoglycemic coma10.2
7coronary aneurysm10.2
8polyarteritis nodosa10.2
9dextrocardia10.2
10posterior myocardial infarction10.2
11inferior myocardial infarction10.2
12kawasaki disease10.2
13diabetic autonomic neuropathy10.2
14aneurysm disease10.2
15autonomic neuropathy10.2
16vasculitis10.2
17cutaneous polyarteritis nodosa10.2
18stroke, ischemic10.0INS
19morbid obesity10.0INS
20hyperthyroidism10.0INS
21hypercholesterolemia10.0INS
22hyperglycemia10.0INS
23gas gangrene10.0PIK3C2A
24malignant hyperthermia10.0PIK3C2A
25cholera10.0INS
26metabolic acidosis10.0PIK3C2A
27respiratory failure10.0PIK3C2A
28eosinophilia10.0PIK3C2A
29myotonic dystrophy10.0PIK3C2A
30dermatomyositis10.0PIK3C2A
31myositis10.0PIK3C2A
32thrombocytopenia10.0PIK3C2A
33infertility10.0INS
34dilated cardiomyopathy10.0PIK3C2A
35vascular disease10.0PIK3C2A
36diabetic ketoacidosis10.0PIK3C2A, INS
37hypokalemia10.0PIK3C2A, INS
38hyperuricemia10.0INS, PIK3C2A
39primary hyperoxaluria10.0INS, PIK3C2A
40familial hyperlipidemia10.0INS, PIK3C2A
41coronary artery disease,10.0INS, PIK3C2A
42proteinuria10.0PIK3C2A, INS
43dementia10.0PIK3C2A
44hypothyroidism10.0PIK3C2A, INS
45coronary heart disease10.0INS, PIK3C2A
46myopathy10.0INS, PIK3C2A

Graphical network of the top 20 diseases related to Silent Myocardial Infarction:



Diseases related to silent myocardial infarction

Clinical Features for Silent Myocardial Infarction

Drugs & Therapeutics for Silent Myocardial Infarction

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Silent Myocardial Infarction

Drug clinical trials:

Search ClinicalTrials for Silent Myocardial Infarction

Search NIH Clinical Center for Silent Myocardial Infarction

Search CenterWatch for Silent Myocardial Infarction

Genetic Tests for Silent Myocardial Infarction

Anatomical Context for Silent Myocardial Infarction

Sources:
33MalaCards
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MalaCards organs/tissues related to Silent Myocardial Infarction:

33
Lung, Heart

Animal Models for Silent Myocardial Infarction or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Silent Myocardial Infarction

Sources:
51PubMed
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Articles related to Silent Myocardial Infarction:

(show top 50)    (show all 63)
idTitleAuthorsYear
1
Clinical characteristics of silent myocardial ischemia diagnosed with adenosine stress 99mTc-tetrofosmin myocardial scintigraphy in Japanese patients with acute cerebral infarction. (22124530)
2013
2
An unusual case of silent acute ST-elevation myocardial infarction following amphetamine use. (24353688)
2013
3
Prognostic significance of silent myocardial infarction in newly diagnosed type 2 diabetes mellitus: United Kingdom Prospective Diabetes Study (UKPDS) 79. (23362315)
2013
4
Prevalence, extent, and independent predictors of silent myocardial infarction. (23597799)
2013
5
Is silent myocardial infarction more common in women with type 2 diabetes than in men? (22446034)
2012
6
Silent myocardial infarction during hypoglycemic coma. (22276266)
2012
7
An unusual case of left ventricular free wall rupture caused by a silent myocardial infarction. (23170099)
2012
8
Prevalence, incidence, predictive factors and prognosis of silent myocardial infarction: a review of the literature. (21497307)
2011
9
Silent myocardial infarction: the risk beyond the first admission. (20813725)
2010
10
Does silent myocardial infarction add prognostic value in ST-elevation myocardial infarction patients without a history of prior myocardial infarction? Insights from the Assessment of Pexelizumab in Acute Myocardial Infarction (APEX-AMI) Trial. (20934561)
2010
11
Coronary aneurysm and silent myocardial infarction in an adolescent secondary to undiagnosed childhood Kawasaki disease. (20664770)
2010
12
Cerebral transient ischemic attack due to left ventricular thrombus formation in a young patient with silent myocardial infarction and normal coronary arteries. (18160151)
2009
13
Silent inferior myocardial infarction with extensive right ventricular scarring. (17643510)
2008
14
Silent myocardial infarction in women with type II diabetes mellitus and microalbuminuria. (19209251)
2008
15
The prevalence and prognosis of unrecognized myocardial infarction and silent myocardial ischemia in patients undergoing major vascular surgery. (17925612)
2007
16
Unruptured giant left ventricular pseudoaneurysm complicating silent myocardial infarction in a diabetic young adult: left ventricular giant pseudoaneurysm after silent myocardial infarction. (16015433)
2005
17
Silent myocardial infarction and its prognosis in a community-based cohort of Type 2 diabetic patients: the Fremantle Diabetes Study. (14963648)
2004
18
Detection of a silent myocardial infarction with phosphor-31 two-dimensional chemical shift imaging (31P 2-D CSI). (12928747)
2003
19
Association of two silent polymorphisms of platelet glycoprotein Ia/IIa receptor with risk of myocardial infarction: a case-control study. (9950439)
1999
20
Impairment of plasma fibrinolysis in young survivors of myocardial infarction with silent ischaemia. (9663707)
1998
21
Silent myocardial infarction during hypoglycaemic coma. (8894868)
1996
22
Silent myocardial infarction in Wegener's granulomatosis. (7748024)
1995
23
Importance of thrombosis and thrombolysis in silent ischaemia: comparison of patients with acute myocardial infarction and unstable angina. (8130023)
1994
24
Infection of left ventricular thrombus in a patient with silent myocardial infarction--a unique complication. (8375427)
1993
25
Silent myocardial infarction caused by acute carbon monoxide poisoning]. (8405820)
1993
26
Silent obstruction of the coronary stenosis between diagnostic angiography and later percutaneous transluminal coronary angioplasty without myocardial infarction. (2063401)
1991
27
Silent myocardial infarction discovered during indium-111 white blood cell imaging. (3383524)
1988
28
Utility of echocardiography in diagnosis of ventricular septal rupture following electrocardiographically silent myocardial infarction. (3450564)
1987
29
Silent myocardial infarction and diabetic cardiovascular autonomic neuropathy. (3778054)
1986
30
Complete AV heart block during acute silent myocardial infarction detected only by myocardial perfusion scintigraphy. (4048796)
1985
31
Silent myocardial infarction in the elderly. (6473293)
1984
32
Silent myocardial infarction in the diabetic population. (6711568)
1984
33
Coincidence of cerebrovascular accident and silent myocardial infarction. (6215869)
1982
34
Gallium-67 uptake in silent myocardial infarction: a case report. (693859)
1978
35
SILENT MYOCARDIAL INFARCTION WITH POSTERIOR INFERIOR PSEUDOANEURYSM OF THE LEFT VENTRICLE PRESENTING AS A POSTERIOR LUNG MASS. (15216055)
1978
36
Silent mitral regurgitation complicating silent myocardial infarction: hemodynamic and morphologic documentation. (5050232)
1972
37
Silent myocardial infarction in a chronic psychotic population. (5089995)
1971
38
The variables of silent myocardial infarction in a psychotic population. (5470675)
1970
39
Silent myocardial infarction in USAF flyers detected solely by annual required electrocardiograms. (5446925)
1970
40
Silent myocardial infarction in mirror-image dextrocardia. (5371988)
1969
41
Silent myocardial infarction. (5634865)
1968
42
Components of the coronary-prone behavior pattern. Their relation to silent myocardial infarction and blood lipids. (5966009)
1966
43
Silent myocardial infarction in diabetes mellitus. (13859554)
1962
44
Sudden arterial occlusion: a clue to silent myocardial infarction. (13904888)
1962
45
Silent myocardial infarction. EKG survey of mentally ill patients at the Hudson River State Hospital. (14415836)
1960
46
Silent myocardial infarction. (13673172)
1959
47
The simultaneous occurrence of perforated peptic ulcer and silent myocardial infarction. (13580284)
1958
48
Silent myocardial infarction; a case report with a brief review of literature. (13431149)
1957
49
Silent myocardial infarction. (13094919)
1953
50
The so-called silent myocardial infarction. (18148882)
1949

Genetic Variations for Silent Myocardial Infarction

Expression for genes affiliated with Silent Myocardial Infarction

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Silent Myocardial Infarction

Search GEO for disease gene expression data for Silent Myocardial Infarction.

Pathways for genes affiliated with Silent Myocardial Infarction

Sources:
38NCBI BioSystems Database, 30KEGG, 50PharmGKB
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Pathways related to Silent Myocardial Infarction according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
9.1INS, PIK3C2A
2
Hide members
9.1INS, PIK3C2A
3
Hide members
9.1INS, PIK3C2A

Compounds for genes affiliated with Silent Myocardial Infarction

Sources:
45Novoseek, 29IUPHAR, 11DrugBank, 50PharmGKB, 24HMDB
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Compounds related to Silent Myocardial Infarction according to GeneCards/GeneDecks:

(show all 15)
idCompoundScoreTop Affiliating Genes
1gemfibrozil45 29 1111.4INS, PIK3C2A
2bezafibrate45 29 1111.4INS, PIK3C2A
3fenofibrate45 50 1111.4INS, PIK3C2A
4uric acid45 2410.4PIK3C2A, INS
5thyroxine45 2410.4INS, PIK3C2A
6glycerol45 11 2411.4INS, PIK3C2A
7acth459.3INS, PIK3C2A
8epinephrine45 11 2411.3PIK3C2A, INS
9fibrinogen459.3INS, PIK3C2A
10ly294002459.2INS, PIK3C2A
11wortmannin459.2INS, PIK3C2A
12glycogen45 2410.1PIK3C2A, INS
13creatinine459.1INS, PIK3C2A
14fatty acid459.0INS, PIK3C2A
15lactate458.8INS, PIK3C2A

GO Terms for genes affiliated with Silent Myocardial Infarction

Sources:
16Gene Ontology
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Biological processes related to Silent Myocardial Infarction according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1insulin receptor signaling pathwayGO:0082869.1INS, PIK3C2A

Products for genes affiliated with Silent Myocardial Infarction

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Sources for Silent Myocardial Infarction

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet