MCID: SLN001
MIFTS: 31

Silent Myocardial Infarction malady

Cardiovascular diseases category

Summaries for Silent Myocardial Infarction

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34MalaCards
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MalaCards: Silent Myocardial Infarction is related to diabetes mellitus and neuropathy. An important gene associated with Silent Myocardial Infarction is INS (insulin), and among its related pathways are Regulation of Actin Cytoskeleton and Glioma. The compounds gemfibrozil and bezafibrate have been mentioned in the context of this disorder. Affiliated tissues include heart and lung, and related mouse phenotypes are renal/urinary system and adipose tissue.

Aliases & Classifications for Silent Myocardial Infarction

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Sources:
9Disease Ontology, 63UMLS, 59SNOMED-CT, 41NCIt
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Cardiovascular diseases


Aliases & Descriptions:

silent myocardial infarction 9 63


External Ids:

Disease Ontology9 DOID:5854
NCIt41 C35400

Related Diseases for Silent Myocardial Infarction

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Sources:
18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Silent Myocardial Infarction:



Diseases related to silent myocardial infarction

Symptoms for Silent Myocardial Infarction

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Drugs & Therapeutics for Silent Myocardial Infarction

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

Search CenterWatch for Silent Myocardial Infarction

Drug clinical trials:

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Search NIH Clinical Center for Silent Myocardial Infarction

Search CenterWatch for Silent Myocardial Infarction

Genetic Tests for Silent Myocardial Infarction

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Anatomical Context for Silent Myocardial Infarction

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Sources:
34MalaCards
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MalaCards organs/tissues related to Silent Myocardial Infarction:

34
Heart, Lung

Animal Models for Silent Myocardial Infarction or affiliated genes

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38MGI
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MGI Mouse Phenotypes related to Silent Myocardial Infarction:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053679.1INS, PIK3C2A
2MP:00053758.8INS, PIK3C2A

Publications for Silent Myocardial Infarction

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53PubMed
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Articles related to Silent Myocardial Infarction:

(show top 50)    (show all 55)
idTitleAuthorsYear
1
Prognostic significance of silent myocardial infarction in newly diagnosed type 2 diabetes mellitus: United Kingdom Prospective Diabetes Study (UKPDS) 79. (23362315)
2013
2
Prevalence, extent, and independent predictors of silent myocardial infarction. (23597799)
2013
3
Is silent myocardial infarction more common in women with type 2 diabetes than in men? (22446034)
2012
4
Silent myocardial infarction during hypoglycemic coma. (22276266)
2012
5
An unusual case of left ventricular free wall rupture caused by a silent myocardial infarction. (23170099)
2012
6
Prevalence, incidence, predictive factors and prognosis of silent myocardial infarction: a review of the literature. (21497307)
2011
7
Silent myocardial infarction subsequent to cutaneous polyarteritis nodosa in a patient with positive lupus anticoagulant. (21763578)
2011
8
Silent myocardial infarction: the risk beyond the first admission. (20813725)
2010
9
Does silent myocardial infarction add prognostic value in ST-elevation myocardial infarction patients without a history of prior myocardial infarction? Insights from the Assessment of Pexelizumab in Acute Myocardial Infarction (APEX-AMI) Trial. (20934561)
2010
10
Incidence and predictors of silent myocardial infarction in type 2 diabetes and the effect of fenofibrate: an analysis from the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study. (19797259)
2010
11
Coronary aneurysm and silent myocardial infarction in an adolescent secondary to undiagnosed childhood Kawasaki disease. (20664770)
2010
12
Cerebral transient ischemic attack due to left ventricular thrombus formation in a young patient with silent myocardial infarction and normal coronary arteries. (18160151)
2009
13
Giant left ventricular aneurysm and intraventricular septal defect after silent myocardial infarction. (19329416)
2009
14
The impact of remote patient monitoring in managing silent myocardial infarction in a residential home setting. (17584720)
2007
15
Paradoxical mesentery embolism and silent myocardial infarction in primary antiphospholipid syndrome: a case report. (16543157)
2006
16
Unruptured giant left ventricular pseudoaneurysm complicating silent myocardial infarction in a diabetic young adult: left ventricular giant pseudoaneurysm after silent myocardial infarction. (16015433)
2005
17
Silent myocardial infarction and its prognosis in a community-based cohort of Type 2 diabetic patients: the Fremantle Diabetes Study. (14963648)
2004
18
Silent myocardial infarction in women with impaired glucose tolerance: the Northern Sweden MONICA study. (14498994)
2003
19
Small vessel vasculitis with pulmonary aneurysms and silent myocardial infarction. (12869681)
2003
20
Detection of a silent myocardial infarction with phosphor-31 two-dimensional chemical shift imaging (31P 2-D CSI). (12928747)
2003
21
Silent myocardial infarction in Wegener's granulomatosis. (8612034)
1996
22
Silent myocardial infarction during hypoglycaemic coma. (8894868)
1996
23
Silent myocardial infarction in Wegener's granulomatosis. (7748024)
1995
24
Infection of left ventricular thrombus in a patient with silent myocardial infarction--a unique complication. (8375427)
1993
25
Silent myocardial infarction caused by acute carbon monoxide poisoning]. (8405820)
1993
26
Silent myocardial infarction complicated by asymptomatic ventricular septal defect and deferred rupture of left ventricular pseudoaneurysm. (15227401)
1990
27
Silent myocardial infarction. (2320516)
1990
28
Myocardial abscess after silent myocardial infarction. (2658198)
1989
29
Silent myocardial infarction discovered during indium-111 white blood cell imaging. (3383524)
1988
30
Utility of echocardiography in diagnosis of ventricular septal rupture following electrocardiographically silent myocardial infarction. (3450564)
1987
31
Silent myocardial infarction and diabetic cardiovascular autonomic neuropathy. (3778054)
1986
32
Silent myocardial infarction in the elderly. (6473293)
1984
33
Coincidence of cerebrovascular accident and silent myocardial infarction. (6215869)
1982
34
Gallium-67 uptake in silent myocardial infarction: a case report. (693859)
1978
35
SILENT MYOCARDIAL INFARCTION WITH POSTERIOR INFERIOR PSEUDOANEURYSM OF THE LEFT VENTRICLE PRESENTING AS A POSTERIOR LUNG MASS. (15216055)
1978
36
Silent mitral regurgitation complicating silent myocardial infarction: hemodynamic and morphologic documentation. (5050232)
1972
37
Silent myocardial infarction in a chronic psychotic population. (5089995)
1971
38
The variables of silent myocardial infarction in a psychotic population. (5470675)
1970
39
Silent myocardial infarction in USAF flyers detected solely by annual required electrocardiograms. (5446925)
1970
40
Silent myocardial infarction in mirror-image dextrocardia. (5371988)
1969
41
Silent myocardial infarction. (5634865)
1968
42
Components of the coronary-prone behavior pattern. Their relation to silent myocardial infarction and blood lipids. (5966009)
1966
43
Silent myocardial infarction in diabetes mellitus. (13859554)
1962
44
Sudden arterial occlusion: a clue to silent myocardial infarction. (13904888)
1962
45
Silent myocardial infarction. EKG survey of mentally ill patients at the Hudson River State Hospital. (14415836)
1960
46
Cold foot; postoperative sign of silent myocardial infarction. (13664498)
1959
47
Silent myocardial infarction. (13673172)
1959
48
The simultaneous occurrence of perforated peptic ulcer and silent myocardial infarction. (13580284)
1958
49
Silent myocardial infarction. (13094919)
1953
50
The so-called silent myocardial infarction. (18148882)
1949

Variations for Silent Myocardial Infarction

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Expression for genes affiliated with Silent Myocardial Infarction

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Silent Myocardial Infarction

Search GEO for disease gene expression data for Silent Myocardial Infarction.

Pathways for genes affiliated with Silent Myocardial Infarction

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Sources:
51PathCards, 39NCBI BioSystems Database, 31KEGG, 52PharmGKB
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Pathways related to Silent Myocardial Infarction according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.1INS, PIK3C2A
2
Show member pathways
Signaling Pathways in Glioblastoma39
9.1INS, PIK3C2A
3
Show member pathways
9.1INS, PIK3C2A

Compounds for genes affiliated with Silent Myocardial Infarction

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Sources:
30IUPHAR, 46Novoseek, 12DrugBank, 52PharmGKB, 25HMDB, 62Tocris Bioscience
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Compounds related to Silent Myocardial Infarction according to GeneCards/GeneDecks:

(show all 24)
idCompoundScoreTop Affiliating Genes
1gemfibrozil30 46 1211.5INS, PIK3C2A
2bezafibrate46 30 1211.5INS, PIK3C2A
3fenofibrate46 52 1211.5INS, PIK3C2A
4uric acid46 2510.5PIK3C2A, INS
5thyroxine46 2510.5INS, PIK3C2A
6glycerol46 25 1211.5INS, PIK3C2A
7acth469.5PIK3C2A, INS
8epinephrine46 25 1211.4INS, PIK3C2A
9fibrinogen469.4INS, PIK3C2A
10norepinephrine46 25 1211.4PIK3C2A, INS
11ly294002469.4INS, PIK3C2A
12wortmannin469.4INS, PIK3C2A
13glycogen46 2510.4PIK3C2A, INS
14fatty acid469.4INS, PIK3C2A
15lactate469.4INS, PIK3C2A
16creatinine469.3PIK3C2A, INS
17testosterone46 62 25 1212.3INS, PIK3C2A
18cholesterol46 30 25 1212.3INS, PIK3C2A
19arginine469.2PIK3C2A, INS
20phosphatidylinositol469.2INS, PIK3C2A
21glutamate469.1INS, PIK3C2A
22lipid469.1INS, PIK3C2A
23alanine469.0PIK3C2A, INS
24glucose468.8INS, PIK3C2A

GO Terms for genes affiliated with Silent Myocardial Infarction

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17Gene Ontology
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Biological processes related to Silent Myocardial Infarction according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1insulin receptor signaling pathwayGO:0082869.1INS, PIK3C2A

Products for genes affiliated with Silent Myocardial Infarction

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  • Antibodies
  • Proteins
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  • Antibodies

Sources for Silent Myocardial Infarction

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet