Aliases & Classifications for Sinusitis

Aliases & Descriptions for Sinusitis:

Name: Sinusitis 38 29 52 41 69

Classifications:



Summaries for Sinusitis

MedlinePlus : 41 sinusitis means your sinuses are inflamed. the cause can be an infection or another problem. your sinuses are hollow air spaces within the bones surrounding the nose. they produce mucus, which drains into the nose. if your nose is swollen, this can block the sinuses and cause pain. there are several types of sinusitis, including acute, which lasts up to 4 weeks subacute, which lasts 4 to 12 weeks chronic, which lasts more than 12 weeks and can continue for months or even years recurrent, with several attacks within a year acute sinusitis often starts as a cold, which then turns into a bacterial infection. allergies, nasal problems, and certain diseases can also cause acute and chronic sinusitis. symptoms of sinusitis can include fever, weakness, fatigue, cough, and congestion. there may also be mucus drainage in the back of the throat, called postnasal drip. your health care professional diagnoses sinusitis based on your symptoms and an examination of your nose and face. you may also need imaging tests. treatments include antibiotics, decongestants, and pain relievers. using heat pads on the inflamed area, saline nasal sprays, and vaporizers can also help. nih: national institute of allergy and infectious diseases

MalaCards based summary : Sinusitis is related to middle lobe syndrome and thrombophlebitis migrans, and has symptoms including angina pectoris, coughing and fever. An important gene associated with Sinusitis is IL12RB2 (Interleukin 12 Receptor Subunit Beta 2), and among its related pathways/superpathways are Innate Immune System and Jak-STAT signaling pathway (KEGG). The drugs Augmentin and Avelox I.V. have been mentioned in the context of this disorder. Affiliated tissues include bone, testes and skin, and related phenotypes are immune system and respiratory system

Wikipedia : 71 Sinusitis, also known as a sinus infection or rhinosinusitis, is inflammation of the sinuses resulting... more...

Related Diseases for Sinusitis

Diseases in the Sinusitis family:

Chronic Frontal Sinusitis Frontal Sinusitis
Acute Frontal Sinusitis

Diseases related to Sinusitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 464)
id Related Disease Score Top Affiliating Genes
1 middle lobe syndrome 29.4 CXCL8 IL5
2 thrombophlebitis migrans 29.3 CD79A IL5
3 orbit alveolar rhabdomyosarcoma 29.3 CD79A IL5 RNASE3
4 uveitis 29.2 CD79A MPO
5 tracheitis 29.1 CD79A CXCL8 IL5 RNASE3
6 maxillary sinusitis 12.3
7 sphenoid sinusitis 12.3
8 frontal sinusitis 12.3
9 ethmoid sinusitis 12.2
10 chronic maxillary sinusitis 12.2
11 acute maxillary sinusitis 12.2
12 acute frontal sinusitis 12.2
13 chronic frontal sinusitis 12.2
14 chronic sphenoidal sinusitis 12.2
15 acute sphenoidal sinusitis 12.2
16 rokitansky-aschoff sinuses of the gallbladder 11.9
17 microcornea, glaucoma, and absent frontal sinuses 11.8
18 chronic ethmoiditis 11.8
19 kartagener syndrome 11.6
20 acute ethmoiditis 11.6
21 sinonasal undifferentiated carcinoma 11.5
22 common cold 11.4
23 young syndrome 11.4
24 inverted papilloma 11.2
25 primary ciliary dyskinesia 11.1
26 yellow nail syndrome 11.1
27 phaeohyphomycosis 11.1
28 orbital cellulitis 11.0
29 aspergillosis 11.0
30 cavernous sinus thrombosis 11.0
31 paranasal sinus disease 11.0
32 cystic fibrosis 11.0
33 nasopharyngitis 10.9
34 pharyngitis 10.9
35 van der woude syndrome 10.9
36 mycetoma 10.9
37 zygomycosis 10.9
38 panbronchiolitis, diffuse 10.9
39 wegener granulomatosis 10.8
40 acne inversa, familial, 3 10.7
41 ciliary dyskinesia, primary, 5 10.7
42 olfactory neuroblastoma 10.7
43 acne inversa, familial, 1 10.7
44 acne inversa, familial, 2 10.7
45 common variable immunodeficiency 10.7
46 extranodal nasal nk/t cell lymphoma 10.7
47 ciliary dyskinesia, primary, 1, with or without situs inversus 10.7
48 ciliary dyskinesia, primary, 22 10.6
49 paranasal sinus cancer 10.6
50 respiratory system disease 10.6

Graphical network of the top 20 diseases related to Sinusitis:



Diseases related to Sinusitis

Symptoms & Phenotypes for Sinusitis

UMLS symptoms related to Sinusitis:


angina pectoris, coughing, fever, halitosis, headache, pruritus, snoring, tremor, sinus congestion, sore throat, vertigo/dizziness, equilibration disorder

MGI Mouse Phenotypes related to Sinusitis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 immune system MP:0005387 9.61 CD79A CFTR CYSLTR1 IL12RB2 IL4R IL5
2 respiratory system MP:0005388 9.1 CFTR CYSLTR1 IL4R IL5 LTC4S MUC5B

Drugs & Therapeutics for Sinusitis

FDA approved drugs:

id Drug Name Active Ingredient(s) 17 Company Approval Date
1
Augmentin 17 AMOXICILLIN; CLAVULANATE POTASSIUM SmithKline Beecham Approved February 1996
2
Avelox I.V. 17 MOXIFLOXACIN HYDROCHLORIDE Bayer Approved November 2001
3
Biaxin XL 17 CLARITHROMYCIN Abbott Laboratories Approved March 2000
4
Cipro 17 CIPROFLOXACIN HYDROCHLORIDE; HYDROCORTISONE Bayer Approved June 1997
5
Tequin 17 Bristol-Myers Squibb December, 1999

Drugs for Sinusitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 304)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Amoxicillin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 26787-78-0 33613 2171
2
Montelukast Approved Phase 4 158966-92-8 5281040
3
Cefditoren Approved Phase 4 117467-28-4, 104145-95-1 9571074 9870843
4
Ephedrine Approved Phase 4,Phase 3,Phase 2 299-42-3 9294
5
Pseudoephedrine Approved Phase 4,Phase 3,Phase 2 90-82-4 7028
6
Prednisone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 53-03-2 5865
7
Budesonide Approved Phase 4,Phase 3,Phase 2,Phase 1 51333-22-3 63006 5281004
8
Epinephrine Approved, Vet_approved Phase 4,Phase 3 51-43-4 5816
9
Omalizumab Approved, Investigational Phase 4,Phase 2 242138-07-4
10
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 3 50-28-2 5757 53477783
11
Ethinyl Estradiol Approved Phase 4,Phase 3 57-63-6 5991
12
Moxifloxacin Approved, Investigational Phase 4,Phase 3 354812-41-2, 151096-09-2 152946
13
Norgestimate Approved Phase 4,Phase 3 35189-28-7 6540478
14
Cefdinir Approved Phase 4 91832-40-5 6915944
15
Levofloxacin Approved, Investigational Phase 4,Phase 3 100986-85-4 149096
16
Ofloxacin Approved Phase 4,Phase 3 82419-36-1 4583
17
Telithromycin Approved Phase 4,Phase 3 191114-48-4 5462516
18
Azithromycin Approved Phase 4,Phase 3,Phase 2 83905-01-5 55185 53477736 447043
19
Acetaminophen Approved Phase 4,Phase 2,Phase 3 103-90-2 1983
20
Dextromethorphan Approved Phase 4 125-71-3 5360696 5362449
21
Guaifenesin Approved, Vet_approved Phase 4,Phase 2 93-14-1 3516
22
Doxycycline Approved, Investigational, Vet_approved Phase 4,Phase 2 564-25-0 54671203
23
Triamcinolone Approved, Vet_approved Phase 4,Phase 3 124-94-7 31307
24
Cocaine Approved, Illicit Phase 4 50-36-2 5760 446220
25
Dopamine Approved Phase 4,Phase 2 51-61-6, 62-31-7 681
26
Dexmedetomidine Approved, Vet_approved Phase 4 76631-46-4, 113775-47-6 68602 5311068 56032
27
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
28
Remifentanil Approved Phase 4 132875-61-7 60815
29
Hyaluronic acid Approved, Vet_approved Phase 4 9004-61-9 53477741 24759
30
Almotriptan Approved, Investigational Phase 4 154323-57-6, 181183-52-8 123606
31
Histamine Approved, Investigational Phase 4 75614-87-8, 51-45-6 774
32
Clarithromycin Approved Phase 4,Phase 3 81103-11-9 84029
33
Erythromycin Approved, Vet_approved Phase 4 114-07-8 12560
34
Etanercept Approved, Investigational Phase 4 185243-69-0
35
Methylprednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3 83-43-2 6741
36
Prednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3 50-24-8 5755
37
Omeprazole Approved, Investigational, Vet_approved Phase 4 73590-58-6 4594
38
Oseltamivir Approved Phase 4,Phase 3 204255-11-8, 196618-13-0 65028
39
Cefazolin Approved Phase 4 25953-19-9 656510 33255
40
Cefuroxime Approved Phase 4,Phase 2 55268-75-2 5361202 5479529
41
Clindamycin Approved, Vet_approved Phase 4 18323-44-9 29029
42
Menthol Approved Phase 4,Phase 2 2216-51-5 16666
43
Sulfamethoxazole Approved Phase 4 723-46-6 5329
44
Trimethoprim Approved, Vet_approved Phase 4 738-70-5 5578
45
Metoprolol Approved, Investigational Phase 4 37350-58-6, 51384-51-1 4171
46
Rocuronium Approved Phase 4 119302-91-9, 143558-00-3 441290
47
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
48
Calcium carbonate Approved Phase 4 471-34-1
49
Citalopram Approved Phase 4 59729-33-8 2771
50
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 2 59-30-3 6037

Interventional clinical trials:

(show top 50) (show all 295)
id Name Status NCT ID Phase
1 Middle Meatal Bacteriology During Acute Respiratory Infection in Children Unknown status NCT00545961 Phase 4
2 Comparison of Daily Mometasone Furoate Nasal Spray Alone Versus a Combination With Montelukast for Treatment of Chronic Rhinosinusitis With Asthma After Functional Endoscopic Sinus Surgery Unknown status NCT02110654 Phase 4
3 Study of Cefditoren Pivoxil in Treatment of Childhood With Acute Rhinosinusitis Unknown status NCT01553006 Phase 4
4 Sinuclean's Treatment Of Sinusitis' Symptoms Completed NCT00747747 Phase 4
5 Xolair in Patients With Chronic Sinusitis Completed NCT00117611 Phase 4
6 Trial to Evaluate Time to Symptom Relief and Elimination of Infecting Bacteria in Treating Sinusitis With Avelox Completed NCT00668304 Phase 4
7 Study of the Safety and Efficacy of Cefdinir and Levofloxacin for the Treatment of Subjects With Acute Bacterial Sinusitis Completed NCT00645073 Phase 4
8 Efficacy and Safety of Sinusitis Hevert SL Tablets Compared to Placebo in Adult Patients With Acute, Uncomplicated Rhinosinusitis Completed NCT02296814 Phase 4
9 Comparison Study Between Cefdinir & Amoxicilline/Clavulanate in Acute Sinusitis and Assessment of Quality of Life Completed NCT00147914 Phase 4
10 CHOOSE : Telithromycin, Acute Bacterial Sinusitis Completed NCT00174694 Phase 4
11 Zmax Compared to Augmentin in Sinusitis Completed NCT00367120 Phase 4
12 Treatment of Acute Sinusitis Completed NCT00377403 Phase 4
13 Duration of Antibiotic Therapy as Part of Maximal Medical Therapy for Chronic Rhinosinusitis Completed NCT01825408 Phase 4
14 Saline Irrigation After Surgery in Patients With Chronic Sinusitis Completed NCT01575223 Phase 4
15 The Optimal Head Position for Distributing Topical Nasal Medication Using the Mucosal Atomization Device Completed NCT02079792 Phase 4
16 Medicated Punctured-Glove-Finger Spacer Study Completed NCT01420471 Phase 4
17 Hemostatic Matrix in Endoscopic Sinus Surgery Completed NCT00242437 Phase 4
18 Study of Asthma and Nasal Steroids Completed NCT01118312 Phase 4
19 The PIO II Study of In-office Placement of a Steroid-eluting Sinus Implant Completed NCT02668302 Phase 4
20 Comparison of Topical Vasoconstriction in Endoscopic Sinus Surgery Completed NCT01706952 Phase 4
21 Randomized Controlled Trial to Evaluate of Dexmedetomidine for the Effect on Operative Visibility in Patients Undergoing Endoscopic Sinus Surgery Completed NCT01569048 Phase 4
22 Study to Evaluate Safety and Effectiveness of AdvaCoat Sinus Gel Completed NCT00554190 Phase 4
23 Evaluation of Histamine, CGRP and VIP as Markers for Activation of Trigeminal and Parasympathetic Nerve Fibers Completed NCT00208065 Phase 4
24 Use of Probiotics as Adjunctive Treatment for Chronic Rhinosinusitis Completed NCT00396162 Phase 4
25 The Effect of Packing in Post Operative Management of FESS Completed NCT00793117 Phase 4
26 Aizthromycin or Clarithromycin in H-pylori Eradication Regimen Completed NCT01667692 Phase 4
27 Study of Enbrel in Rheumatoid Arthritis (RA) Subjects With Comorbid Disorders Completed NCT00132418 Phase 4
28 The Impact Of The Addition Of Budesonide To Low-Pressure, High-Volume Saline Sinus Irrigation For Chronic Rhinosinusitis Completed NCT02696850 Phase 4
29 Telithromycin in Respiratory Tract Infections Completed NCT00261105 Phase 4
30 Proteomic Profiling for Influenza Completed NCT00133588 Phase 4
31 Systemic Methylprednisolone in Chronic Rhinosinusitis Completed NCT01205984 Phase 4
32 Omeprazole 20 mg in Patients With Laryngopharyngeal reflux and Comorbid Chronic Rhinosinusitis Completed NCT03086070 Phase 4
33 The Efficacy and Safety of Hyeonggaeyeongyo-tang for Chronic Rhinitis According to Pattern Identification in Korean Medicine Completed NCT02477293 Phase 4
34 The Efficacy and Complication of Gentamicin Nasal Irrigation in Chronic Rhinosinusitis and Recurrent Sinusitis Recruiting NCT02582099 Phase 4
35 Improvement of Outcomes in Draf III/Endoscopic Modified Lothrop Procedure Recruiting NCT02981017 Phase 4
36 Response of the Airway in Sinusitis and Asthma Recruiting NCT03011632 Phase 4
37 Prophylactic Antibiotics After Functional Endoscopic Sinus Surgery: a Randomized, Double-blind Placebo Controlled Trial Recruiting NCT01919411 Phase 4
38 Prophylactic Oral Antibiotics on Sinonasal Outcomes Following Endoscopic Transsphenoidal Surgery for Pituitary Lesions Recruiting NCT03014687 Phase 4
39 Remifentanil and Controlled Hypotension for Functional Endoscopic Sinus Surgery: Comparison With Tramadol and Metoprolol Recruiting NCT02484859 Phase 4
40 Azithromycin for Patients With Chronic Rhinosinusitis Failing Medical and Surgical Therapy Recruiting NCT02307825 Phase 4
41 Systemic Corticosteroids in the Perioperative Management of Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP) Recruiting NCT02119273 Phase 4
42 Chronic Rhinosinusitis With or Without Nasal Polyps Steroid Study Active, not recruiting NCT00841802 Phase 4
43 A Trial of Oseltamivir in High-Risk Patients Presenting to the Emergency Department With Influenza Not yet recruiting NCT02561169 Phase 4
44 Study to Measure the Impact of Antibiotics on Bacterial Flora in Adults With Acute Sinusitis Terminated NCT00245440 Phase 4
45 Sinusitis and Facial Pain Disorders Anti-Depression Trial Terminated NCT00754793 Phase 4
46 Study of the Use of LUMA Lightwire Terminated NCT00705237 Phase 4
47 Study to Evaluate the Efficacy and Safety of Moxifloxacin Versus Amoxicillin/Clavulanate in the Treatment of Acute Bacterial Rhinosinusitis Terminated NCT00493038 Phase 4
48 Canadian Health Economics, Outcome, and Effectiveness Comparison of Treatment in Patients With Chronic Rhinosinusitis Terminated NCT01455948 Phase 4
49 Corticosteroid Therapy for Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP) Terminated NCT01676415 Phase 4
50 Surgical Reduction of the Inferior Turbinates for Nasal Obstruction Terminated NCT00737906 Phase 4

Search NIH Clinical Center for Sinusitis

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Genetic Tests for Sinusitis

Genetic tests related to Sinusitis:

id Genetic test Affiliating Genes
1 Sinusitis 29

Anatomical Context for Sinusitis

MalaCards organs/tissues related to Sinusitis:

39
Bone, Testes, Skin, Brain, Tonsil, Lymph Node, T Cells

Publications for Sinusitis

Articles related to Sinusitis:

(show top 50) (show all 1726)
id Title Authors Year
1
Improvement of psychiatric symptoms in youth following resolution of sinusitis. ( 28012531 )
2017
2
Delayed Diagnosis of a Nasal Type Lymphoma Misdiagnosed as Persistent Sinusitis. ( 28061034 )
2017
3
Salmonella enterica Subspecies diarizonae Maxillary Sinusitis in a Snake Handler: First Report. ( 27186588 )
2016
4
Badly Behaving Noses in Children: Rhinitis, Sinusitis, or Neither? ( 27841920 )
2016
5
Evaluation of the efficacy of curcumin in experimentally induced acute sinusitis in rats. ( 27929603 )
2016
6
USE OF COMPUTED TOMOGRAPHY FOR INVESTIGATION OF RHINITIS AND SINUSITIS IN A GREATER RHEA (RHEA AMERICANA). ( 28080910 )
2016
7
Radiological and clinical difficulties in the management of chronic maxillary sinusitis in I^ Thalassemic paediatric patients. ( 27063757 )
2016
8
Differential protein expression in the secretory fluids of maxillary sinusitis and maxillary retention cyst. ( 27422628 )
2016
9
Single-center retrospective series of fourteen patients with mucosal melanoma of the nasal cavity and paranasal sinuses. ( 27502822 )
2016
10
Medical Management of Frontal Sinusitis. ( 27329981 )
2016
11
Rare and Serious Complications of Sinusitis in Pediatric Patients: Epidural Abscess. ( 28027170 )
2016
12
Sporotrichosis of Maxillary Sinuses in a Middle Aged Female Patient from Rural Area of Eastern India. ( 27134873 )
2016
13
Are Zygomatic Implants Associated With Maxillary Sinusitis? ( 27070844 )
2016
14
Pott's puffy tumor: rare complication of sinusitis. ( 27593895 )
2016
15
A 44-Year-Old Man with Waldenstrom Macroglobulinemia and Bilateral Maxillary Sinusitis. ( 27840358 )
2016
16
Socioeconomic Disparities in the Presentation of Acute Bacterial Sinusitis Complications in the Pediatric Population. ( 27128685 )
2016
17
Lymphoma of the nasal cavity and paranasal sinuses: A case series. ( 27657899 )
2016
18
Haemophilus parainfluenzae endocarditis with systemic embolisation following maxillary sinusitis. ( 27599807 )
2016
19
Bone Remodeling around Implants Placed in Augmented Sinuses in Patients with and without History of Periodontitis. ( 27633527 )
2016
20
Outcomes of chronic frontal sinusitis treated with ethmoidectomy: a prospective study. ( 26879467 )
2016
21
Fungal Mycotic Aneurysm of the Internal Carotid Artery Associated with Sphenoid Sinusitis in an Immunocompromised Patient: A Case Report and Review of the Literature. ( 26687073 )
2016
22
Sinusitis. ( 27622225 )
2016
23
Balloon dilation of the sphenoid sinus ostium for recurrent sphenoid sinusitis. ( 27551838 )
2016
24
Headache with markedly hypodense cerebral venous sinuses. ( 27625436 )
2016
25
Predictive factors in patients undergoing endoscopic sinus surgery for odontogenic sinusitis. ( 27028710 )
2016
26
Contralateral Hypoplastic Venous Draining Sinuses Are Associated with Elevated Intracranial Pressure in Unilateral Cerebral Sinovenous Thrombosis. ( 27469210 )
2016
27
Utilization of computer-aided detection system in diagnosing unilateral maxillary sinusitis on panoramic radiographs. ( 26837670 )
2016
28
Results of transnasal transostial sphenoidotomy in 79A cases of chronic sphenoid sinusitis. ( 27079741 )
2016
29
Incidental paranasal sinusitis on routine brain magnetic resonance scans: association with atherosclerosis. ( 27509266 )
2016
30
Clinical Inquiry: Which treatments are safe and effective for chronic sinusitis? ( 28087873 )
2016
31
Chronic invasive fungal sinusitis: characterization and shift in management of a rare disease. ( 27463614 )
2016
32
Management of frontal sinusitis-associated subperiosteal abscess in children less than 9A years of age. ( 27810421 )
2016
33
Acute sinusitis. ( 27990044 )
2016
34
Chronic invasive fungal sinusitis causing a pathologic Le Fort I fracture in an immunocompetent patient. ( 27657320 )
2016
35
In this issue - November 2016: More education needed on health hazards of chemotherapy agents A^ Congenital disseminated neosporosis in a pup A^ Obstructive hydrocephalus in two dogs A^ Iodine packing of the sinuses for aspergillosis A^ Buffalos unlikely to be a large risk for BVDV infection in cattle A^ Obesity in ponies A^ Death of a white rhino. ( 27785802 )
2016
36
CLINICAL PRACTICE. Acute Sinusitis in Adults. ( 27602668 )
2016
37
Management of acute maxillary sinusitis after sinus bone grafting procedures with simultaneous dental implants placement - a retrospective study. ( 27169511 )
2016
38
Sinusitis in patients on tumor necrosis factor alpha inhibitors. ( 27958666 )
2016
39
Role of Anatomic variations of Uncinate Process in Frontal Sinusitis. ( 27833869 )
2016
40
Sporadic Burkitt Lymphoma Presenting as Acute Pancreatitis, Concurrent Sinusitis, and Enlarged Adenoids. ( 27213067 )
2016
41
Extramedullary Plasmacytoma of the Paranasal Sinuses: Combining Surgery with External Radiotherapy. ( 27066407 )
2016
42
Metastatic mammary carcinoma to the orbit masquerading as maxillary sinusitis. ( 27103558 )
2016
43
Invasive Fungal Sinusitis by Lasiodiplodia theobromae in an Patient with Aplastic Anemia: An Extremely Rare Case Report and Literature Review. ( 27650099 )
2016
44
Chronic Sinusitis and Risk of Head and Neck Cancer in the US Elderly Population. ( 27606895 )
2016
45
Relationship between dacryoadenitis subtype of idiopathic orbital inflammatory pseudotumor and paranasal sinusitis. ( 27158618 )
2016
46
Superior Branch Palsy of the Oculomotor Nerve Caused by Frontal Sinusitis. ( 27100635 )
2016
47
Multiple Cerebrovascular Complications due to Sphenoid Sinusitis. ( 28050478 )
2016
48
Rapid development of a mycotic aneurysm of the intracranial artery secondary to Scedosporium apiospermum sinusitis. ( 28053848 )
2016
49
Orbital Cellulitis, Cavernous Sinus Thrombosis, Internal Jugular Vein Thrombus, and Clival Osteomyelitis Secondary to Acute Sinusitis. ( 27983875 )
2016
50
Possible allergic fungal sinusitis. ( 27055989 )
2016

Variations for Sinusitis

Expression for Sinusitis

LifeMap Discovery
Genes differentially expressed in tissues of Sinusitis patients vs. healthy controls: 35 (show all 38)
id Gene Description Tissue Up/Dn Fold Change (log2) P value
1 FDCSP follicular dendritic cell secreted protein Nose + 5.87 0.000
2 MUC7 mucin 7, secreted Nose + 5.43 0.001
3 PIP prolactin-induced protein Nose + 5.28 0.000
4 STATH statherin Nose + 5.17 0.000
5 KRT14 keratin 14, type I Nose + 4.90 0.000
6 CRISP3 cysteine-rich secretory protein 3 Nose + 4.46 0.007
7 C6orf58 chromosome 6 open reading frame 58 Nose + 4.30 0.002
8 BPIFB2 BPI fold containing family B, member 2 Nose + 4.26 0.002
9 IGHM immunoglobulin heavy constant mu Nose + 4.22 0.000
10 ZG16B zymogen granule protein 16B Nose + 3.91 0.000
11 LOC285628 MIR146A host gene Nose + 3.85 0.000
12 CXCL13 chemokine (C-X-C motif) ligand 13 Nose + 3.84 0.001
13 AZGP1 alpha-2-glycoprotein 1, zinc-binding Nose + 3.78 0.001
14 SEC14L3 SEC14-like lipid binding 3 Nose - 3.72 0.000
15 TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) Nose + 3.70 0.000
16 DSG3 desmoglein 3 Nose + 3.65 0.000
17 DMBT1 deleted in malignant brain tumors 1 Nose + 3.65 0.003
18 SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) Nose - 3.61 0.000
19 GREM2 gremlin 2, DAN family BMP antagonist Nose - 3.60 0.002
20 SLC26A4 solute carrier family 26 (anion exchanger), member 4 Nose + 3.55 0.001
21 PRB3 proline-rich protein BstNI subfamily 3 Nose + 3.55 0.001
22 LTF lactotransferrin Nose + 3.49 0.008
23 FLJ26850 FLJ26850 protein Nose - 3.49 0.000
24 NCAPG non-SMC condensin I complex, subunit G Nose + 3.48 0.000
25 DUOX2 dual oxidase 2 Nose + 3.43 0.007
26 MUC5B mucin 5B, oligomeric mucus/gel-forming Nose + 3.41 0.000
27 LPO lactoperoxidase Nose + 3.31 0.003
28 C15orf48 chromosome 15 open reading frame 48 Nose + 3.29 0.001
29 STK33 serine/threonine kinase 33 Nose - 3.28 0.008
30 CXCL5 chemokine (C-X-C motif) ligand 5 Nose + 3.20 0.001
31 CXorf57 chromosome X open reading frame 57 Nose - 3.16 0.002
32 ODAM odontogenic, ameloblast asssociated Nose + 3.12 0.007
33 IDO1 indoleamine 2,3-dioxygenase 1 Nose + 3.11 0.011
34 TF transferrin Nose + 3.11 0.000
35 CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) Nose + 3.11 0.003
36 PRB4 proline-rich protein BstNI subfamily 4 Nose + 3.09 0.005
37 LRP1B low density lipoprotein receptor-related protein 1B Nose - 3.06 0.003
38 CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 Nose - 3.04 0.001
Search GEO for disease gene expression data for Sinusitis.

Pathways for Sinusitis

GO Terms for Sinusitis

Cellular components related to Sinusitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.5 CXCL8 DEFB4A IL4R IL5 MPO MUC5B
2 extracellular space GO:0005615 9.17 CXCL8 DEFB4A IL4R IL5 MPO MUC5B

Biological processes related to Sinusitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.62 CXCL8 DEFB4A IL4R IL5
2 chemotaxis GO:0006935 9.43 CXCL8 CYSLTR1 DEFB4A
3 cytokine-mediated signaling pathway GO:0019221 9.33 IL12RB2 IL4R IL5
4 defense response to bacterium GO:0042742 9.26 DEFB4A MPO MUC5B RNASE3
5 defense response GO:0006952 8.92 CXCL8 CYSLTR1 DEFB4A MPO

Molecular functions related to Sinusitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytokine receptor activity GO:0004896 8.62 IL12RB2 IL4R

Sources for Sinusitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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