MCID: SKL007
MIFTS: 32

Skeletal Muscle Regeneration malady

Bone diseases category
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Summaries for Skeletal Muscle Regeneration

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Wikipedia:65 Hereditary inclusion body myopathies (HIBM) are a heterogeneous group of genetic disorders which have... more...

MalaCards based summary: Skeletal Muscle Regeneration, also known as hereditary inclusion body myopathy, is related to myopathy and dementia. An important gene associated with Skeletal Muscle Regeneration is TNFSF12 (tumor necrosis factor (ligand) superfamily, member 12), and among its related pathways are WNT Signaling and Wnt Signaling Pathway. Affiliated tissues include skeletal muscle, bone and endothelial, and related mouse phenotype muscle.

Aliases & Classifications for Skeletal Muscle Regeneration

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Skeletal Muscle Regeneration, Aliases & Descriptions:

Name: Skeletal Muscle Regeneration 65
 
Hereditary Inclusion Body Myopathy 65 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Bone diseases


Related Diseases for Skeletal Muscle Regeneration

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Diseases related to Skeletal Muscle Regeneration via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 23)
idRelated DiseaseScoreTop Affiliating Genes
1myopathy11.1
2dementia10.5
3muscular dystrophy10.5
4frontotemporal dementia10.4
5hereditary inclusion body myopathy type 410.4
6endotheliitis10.4
7leukemia10.3
8ischemia10.3
9myositis10.3
10rhabdomyosarcoma10.3
11gne-related myopathy10.3
12hereditary myopathy with early respiratory failure10.3
13diabetes mellitus10.2
14duchenne muscular dystrophy10.2
15obesity10.2
16limb ischemia10.2
17inclusion body myositis10.2
18compartment syndrome10.2
19endometriosis10.2
20thyroiditis10.2
21myotonic dystrophy10.2
22polymyositis10.2
23hypoxia10.2

Graphical network of the top 20 diseases related to Skeletal Muscle Regeneration:



Diseases related to skeletal muscle regeneration

Symptoms for Skeletal Muscle Regeneration

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Drugs & Therapeutics for Skeletal Muscle Regeneration

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Drug clinical trials:

Search ClinicalTrials for Skeletal Muscle Regeneration

Search NIH Clinical Center for Skeletal Muscle Regeneration

Genetic Tests for Skeletal Muscle Regeneration

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Anatomical Context for Skeletal Muscle Regeneration

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MalaCards organs/tissues related to Skeletal Muscle Regeneration:

32
Skeletal muscle, Bone, Endothelial, Bone marrow, Brain, Thyroid, Myeloid, Monocytes, T cells, Tongue, Neutrophil

Animal Models for Skeletal Muscle Regeneration or affiliated genes

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MGI Mouse Phenotypes related to Skeletal Muscle Regeneration:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053699.0BCL9, IFRD1, WNT10B

Publications for Skeletal Muscle Regeneration

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Articles related to Skeletal Muscle Regeneration:

(show top 50)    (show all 238)
idTitleAuthorsYear
1
Leucine supplementation improves skeletal muscle regeneration after cryolesion in rats. (24416379)
2014
2
Altered macrophage phenotype transition impairs skeletal muscle regeneration. (24525152)
2014
3
Intramuscular administration of PEGylated IGF-I improves skeletal muscle regeneration after myotoxic injury. (23608055)
2013
4
Monocyte/macrophage interactions with myogenic precursor cells during skeletal muscle regeneration. (23384231)
2013
5
Myeloid hypoxia-inducible factor-1I+ is essential for skeletal muscle regeneration in mice. (23729446)
2013
6
Delta-like 1 homolog (dlk1): a marker for rhabdomyosarcomas implicated in skeletal muscle regeneration. (23577150)
2013
7
microRNA-206 promotes skeletal muscle regeneration and delays progression of Duchenne muscular dystrophy in mice. (22546853)
2012
8
Biochemical and mechanical environment cooperatively regulate skeletal muscle regeneration. (22415307)
2012
9
Tissue engineering for skeletal muscle regeneration. (23738301)
2012
10
MASTR directs MyoD-dependent satellite cell differentiation during skeletal muscle regeneration. (22279050)
2012
11
Impaired skeletal muscle regeneration in the absence of fibrosis during hibernation in 13-lined ground squirrels. (23155423)
2012
12
Sdf-1 (CXCL12) improves skeletal muscle regeneration via the mobilisation of Cxcr4 and CD34 expressing cells. (22978573)
2012
13
Sca-1 influences the innate immune response during skeletal muscle regeneration. (21123737)
2011
14
PC4/Tis7/IFRD1 stimulates skeletal muscle regeneration and is involved in myoblast differentiation as a regulator of MyoD and NF-kappaB. (21127072)
2011
15
Uncovering the transcriptional circuitry in skeletal muscle regeneration. (21509518)
2011
16
Macrophage-specific expression of urokinase-type plasminogen activator promotes skeletal muscle regeneration. (21709151)
2011
17
Sphingosine 1-phosphate signaling is involved in skeletal muscle regeneration. (20042733)
2010
18
Sca-1 expression is required for efficient remodeling of the extracellular matrix during skeletal muscle regeneration. (19059231)
2009
19
Matrix metalloproteinase-9 inhibition ameliorates pathogenesis and improves skeletal muscle regeneration in muscular dystrophy. (19401296)
2009
20
Acceleration of skeletal muscle regeneration in a rat skeletal muscle injury model by local injection of human peripheral blood-derived CD133-positive cells. (19353523)
2009
21
Age influences the early events of skeletal muscle regeneration: studies of whole muscle grafts transplanted between young (8 weeks) and old (13-21 months) mice. (18364250)
2008
22
Tumor necrosis factor-alpha inhibition of skeletal muscle regeneration is mediated by a caspase-dependent stem cell response. (18258721)
2008
23
Delayed angiogenesis and VEGF production in CCR2-/- mice during impaired skeletal muscle regeneration. (17522124)
2007
24
AHNAK, a novel component of the dysferlin protein complex, redistributes to the cytoplasm with dysferlin during skeletal muscle regeneration. (17185750)
2007
25
Skeletal muscle regeneration may be enhanced by overexpression of aquaporin 1 in intramuscular capillary endothelial cells. (17052860)
2007
26
Modulation of insulin-like growth factor (IGF)-I and IGF-binding protein interactions enhances skeletal muscle regeneration and ameliorates the dystrophic pathology in mdx mice. (17823291)
2007
27
VEGF overexpression via adeno-associated virus gene transfer promotes skeletal muscle regeneration and enhances muscle function in mdx mice. (17575261)
2007
28
Bex1 knock out mice show altered skeletal muscle regeneration. (17884015)
2007
29
Type I insulin-like growth factor receptor signaling in skeletal muscle regeneration and hypertrophy. (17947802)
2007
30
Increased expression of deltaCaMKII isoforms in skeletal muscle regeneration: Implications in dystrophic muscle disease. (16215994)
2006
31
The plasminogen activation system in skeletal muscle regeneration: antagonistic roles of urokinase-type plasminogen activator (uPA) and its inhibitor (PAI-1). (15970552)
2005
32
Hematopoietic contribution to skeletal muscle regeneration by myelomonocytic precursors. (15353585)
2004
33
Sox15 is required for skeletal muscle regeneration. (15367664)
2004
34
Highly coordinated gene regulation in mouse skeletal muscle regeneration. (12477723)
2003
35
Mitochondrial biogenesis during skeletal muscle regeneration. (11882500)
2002
36
Skeletal muscle regeneration after insulin-like growth factor I gene transfer by recombinant Sendai virus vector. (11526451)
2001
37
Regulation of alpha7 integrin by mechanical stress during skeletal muscle regeneration. (11369187)
2001
38
Murray L. Barr Award Lecture. Studies of the dynamics of skeletal muscle regeneration: the mouse came back! (9666302)
1998
39
Skeletal muscle regeneration mimicking rhabdomyosarcoma: a potential diagnostic pitfall. (9762546)
1998
40
Growth factors in skeletal muscle regeneration. (8971480)
1996
41
Skeletal muscle regeneration after injury: an overview. (8167787)
1994
42
Effect of torbafylline on mitochondrial calmitine in mouse skeletal muscle regeneration after injection of a myotoxic drug. (8229057)
1993
43
The role of basic fibroblast growth factor in skeletal muscle regeneration. (1591017)
1992
44
The effect of X-irradiation on skeletal muscle regeneration in the adult rat. (3572447)
1987
45
Time course of changes in protein synthesis in marcaine-induced skeletal muscle regeneration. (6083423)
1984
46
Skeletal muscle regeneration after myonecrosis induced by crude venom and a myotoxin from the snake Bothrops asper (Fer-de-Lance). (6523503)
1984
47
Skeletal muscle: regeneration and transplantation studies. (7020842)
1980
48
Choline acetyltransferase and cholinesterase in skeletal muscle regeneration. (1123632)
1975
49
A histological and histochemical study of skeletal muscle regeneration in polymyositis. (5444895)
1970
50
Origin of myoblasts during skeletal muscle regeneration. Electron microscopic observations. (5776329)
1969

Variations for Skeletal Muscle Regeneration

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Expression for genes affiliated with Skeletal Muscle Regeneration

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Expression patterns in normal tissues for genes affiliated with Skeletal Muscle Regeneration

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Pathways for genes affiliated with Skeletal Muscle Regeneration

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Pathways related to Skeletal Muscle Regeneration according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.5BCL9, WNT10B
2
Show member pathways
Wnt Signaling Pathway NetPath37
9.5BCL9, WNT10B

Compounds for genes affiliated with Skeletal Muscle Regeneration

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GO Terms for genes affiliated with Skeletal Muscle Regeneration

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Cellular components related to Skeletal Muscle Regeneration according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1sarcolemmaGO:0423839.0AQP1, AHNAK2

Biological processes related to Skeletal Muscle Regeneration according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of angiogenesisGO:0457669.2AQP1, TNFSF12
2cellular response to cAMPGO:0713209.2WNT10B, AQP1
3canonical Wnt signaling pathwayGO:0600709.2BCL9, WNT10B
4cellular response to retinoic acidGO:0713009.1WNT10B, AQP1

Products for genes affiliated with Skeletal Muscle Regeneration

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Sources for Skeletal Muscle Regeneration

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet