MCID: SKL007
MIFTS: 42

Skeletal Muscle Regeneration malady

Bone diseases category

Summaries for Skeletal Muscle Regeneration

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63Wikipedia, 32MalaCards
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Wikipedia:63 Hereditary inclusion body myopathies (HIBM) are a heterogeneous group of genetic disorders which have... more...

MalaCards: Skeletal Muscle Regeneration, also known as hereditary inclusion body myopathy, is related to muscular dystrophy and ischemia. An important gene associated with Skeletal Muscle Regeneration is WNT10B (wingless-type MMTV integration site family, member 10B), and among its related pathways are Basal cell carcinoma and Transcription Androgen Receptor nuclear signaling. The compounds matrigel and prostaglandin have been mentioned in the context of this disorder. Affiliated tissues include skeletal muscle, endothelial and bone, and related mouse phenotypes are reproductive system and muscle.

Aliases & Classifications for Skeletal Muscle Regeneration

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63Wikipedia
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Bone diseases


Aliases & Descriptions:

skeletal muscle regeneration 63
hereditary inclusion body myopathy 63


Related Diseases for Skeletal Muscle Regeneration

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Skeletal Muscle Regeneration:



Diseases related to skeletal muscle regeneration

Clinical Features for Skeletal Muscle Regeneration

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Drugs & Therapeutics for Skeletal Muscle Regeneration

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Skeletal Muscle Regeneration

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Genetic Tests for Skeletal Muscle Regeneration

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Anatomical Context for Skeletal Muscle Regeneration

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32MalaCards
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MalaCards organs/tissues related to Skeletal Muscle Regeneration:

32
Skeletal muscle, Endothelial, Bone, Bone marrow, Myeloid, Monocytes, Tongue

Animal Models for Skeletal Muscle Regeneration or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Skeletal Muscle Regeneration:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053899.7AQP1, PLAU, WNT7A, MYOD1, LIF
2MP:00053698.9BCL9, CAPN3, SOX15, LIF, MYOD1, CXCL12
3MP:00053858.7CAPN3, FZD7, LIF, MYOD1, CXCL12, WNT7A

Publications for Skeletal Muscle Regeneration

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50PubMed
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Articles related to Skeletal Muscle Regeneration:

(show top 50)    (show all 260)
idTitleAuthorsYear
1
Monocyte/macrophage interactions with myogenic precursor cells during skeletal muscle regeneration. (23384231)
2013
2
Myeloid hypoxia-inducible factor-1I+ is essential for skeletal muscle regeneration in mice. (23729446)
2013
3
Delta-like 1 homolog (dlk1): a marker for rhabdomyosarcomas implicated in skeletal muscle regeneration. (23577150)
2013
4
The time course effects of electroacupuncture on promoting skeletal muscle regeneration and inhibiting excessive fibrosis after contusion in rabbits. (23990848)
2013
5
Monocarboxylate transporter expression at the onset of skeletal muscle regeneration. (24303150)
2013
6
Heat stress promotes skeletal muscle regeneration after crush injury in rats. (24071519)
2013
7
Unacylated ghrelin promotes skeletal muscle regeneration following hindlimb ischemia via SOD-2-mediated miR-221/222 expression. (24308935)
2013
8
Fundamental Differences in Dedifferentiation and Stem Cell Recruitment during Skeletal Muscle Regeneration in Two Salamander Species. (24268695)
2013
9
The effects of obesity on skeletal muscle regeneration. (24381559)
2013
10
S1P lyase in skeletal muscle regeneration and satellite cell activation: exposing the hidden lyase. (22750505)
2013
11
Skeletal muscle involvement in friedreich ataxia and potential effects of recombinant human erythropoietin administration on muscle regeneration and neovascularization. (22805773)
2012
12
Satellite cells are essential for skeletal muscle regeneration: the cell on the edge returns centre stage. (22833472)
2012
13
PC4/Tis7/IFRD1 stimulates skeletal muscle regeneration and is involved in myoblast differentiation as a regulator of MyoD and NF-kappaB. (21127072)
2011
14
Rantes secreted from macrophages disturbs skeletal muscle regeneration after cardiotoxin injection in Cbl-b-deficient mice. (21254087)
2011
15
Pax7-expressing satellite cells are indispensable for adult skeletal muscle regeneration. (21828093)
2011
16
Intra-arterial transplantation of adult bone marrow cells restores blood flow and regenerates skeletal muscle in ischemic limbs. (19628514)
2009
17
Modulation of caspase activity regulates skeletal muscle regeneration and function in response to vasopressin and tumor necrosis factor. (19440308)
2009
18
Common micro-RNA signature in skeletal muscle damage and regeneration induced by Duchenne muscular dystrophy and acute ischemia. (19528256)
2009
19
Urokinase-type plasminogen activator increases hepatocyte growth factor activity required for skeletal muscle regeneration. (19812386)
2009
20
Age influences the early events of skeletal muscle regeneration: studies of whole muscle grafts transplanted between young (8 weeks) and old (13-21 months) mice. (18364250)
2008
21
Endogenous interferon-gamma is required for efficient skeletal muscle regeneration. (18353892)
2008
22
Skeletal muscle regeneration may be enhanced by overexpression of aquaporin 1 in intramuscular capillary endothelial cells. (17052860)
2007
23
Modulation of insulin-like growth factor (IGF)-I and IGF-binding protein interactions enhances skeletal muscle regeneration and ameliorates the dystrophic pathology in mdx mice. (17823291)
2007
24
Skeletal muscle regeneration: report of a case presenting as a cutaneous nodule following blunt trauma to the lip. (17381808)
2007
25
A naturally occurring calcineurin variant inhibits FoxO activity and enhances skeletal muscle regeneration. (18086917)
2007
26
Xin, an actin binding protein, is expressed within muscle satellite cells and newly regenerated skeletal muscle fibers. (17855775)
2007
27
Rskalpha-actin/hIGF-1 transgenic mice with increased IGF-I in skeletal muscle and blood: impact on regeneration, denervation and muscular dystrophy. (16716629)
2006
28
Participation of stem cells from human cord blood in skeletal muscle regeneration of SCID mice. (16939819)
2006
29
Transition of Homer isoforms during skeletal muscle regeneration. (16236824)
2006
30
Salamander limb regeneration involves the activation of a multipotent skeletal muscle satellite cell population. (16449193)
2006
31
The plasminogen activation system in skeletal muscle regeneration: antagonistic roles of urokinase-type plasminogen activator (uPA) and its inhibitor (PAI-1). (15970552)
2005
32
Sox15 is required for skeletal muscle regeneration. (15367664)
2004
33
A-utrophin up-regulation in mdx skeletal muscle is independent of regeneration. (14659408)
2004
34
Transient up-regulation of biglycan during skeletal muscle regeneration: delayed fiber growth along with decorin increase in biglycan-deficient mice. (15063173)
2004
35
Myogenic and nonmyogenic cells differentially express proteinases, Hsc/Hsp70, and BAG-1 during skeletal muscle regeneration. (12791605)
2003
36
Mitochondrial biogenesis during skeletal muscle regeneration. (11882500)
2002
37
Kinetics of myoblast proliferation show that resident satellite cells are competent to fully regenerate skeletal muscle fibers. (12441128)
2002
38
Plasmin activity is required for myogenesis in vitro and skeletal muscle regeneration in vivo. (11929773)
2002
39
Skeletal muscle regeneration associated with the stroma reaction during tumor invasion in the rat tongue. (12575835)
2002
40
The expression of intermediate filament protein nestin as related to vimentin and desmin in regenerating skeletal muscle. (11398835)
2001
41
The role of tumor necrosis factor-alpha (TNF-alpha) in skeletal muscle regeneration. Studies in TNF-alpha(-/-) and TNF-alpha(-/-)/LT-alpha(-/-) mice. (11457927)
2001
42
Skeletal muscle regeneration is not impaired in Fgf6 -/- mutant mice. (10872817)
2000
43
Murray L. Barr Award Lecture. Studies of the dynamics of skeletal muscle regeneration: the mouse came back! (9666302)
1998
44
Interactions between tissues engaged in wound repair and skeletal muscle regeneration. (8986462)
1996
45
Association of an unusual form of a Pax7-like gene with increased efficiency of skeletal muscle regeneration. (7590262)
1995
46
Leukemia inhibitory factor (LIF) infusion stimulates skeletal muscle regeneration after injury: injured muscle expresses lif mRNA. (8064301)
1994
47
Immunohistochemical analysis of myoblast proliferation and differentiation in experimental skeletal muscle regeneration. (8105886)
1993
48
Skeletal muscle regeneration and plasticity of grafts. (8504844)
1993
49
Glycolysis in skeletal muscle regeneration. (133807)
1976
50
A histological and histochemical study of skeletal muscle regeneration in polymyositis. (5444895)
1970

Genetic Variations for Skeletal Muscle Regeneration

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Expression for genes affiliated with Skeletal Muscle Regeneration

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Skeletal Muscle Regeneration

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Pathways for genes affiliated with Skeletal Muscle Regeneration

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29KEGG, 59Tocris Bioscience, 12EMD Millipore, 51QIAGEN, 52R&D Systems, 37NCBI BioSystems Database
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Compounds for genes affiliated with Skeletal Muscle Regeneration

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44Novoseek, 11DrugBank, 24HMDB, 49PharmGKB, 2BitterDB, 59Tocris Bioscience, 28IUPHAR
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Compounds related to Skeletal Muscle Regeneration according to GeneCards/GeneDecks:

(show all 18)
idCompoundScoreTop Affiliating Genes
1matrigel4410.1PLAU, MME, CXCL12, LIF
2prostaglandin4410.1LIF, MYOD1, CXCL12, MME
3ribonucleic acid4410.0LIF, CXCL12, MME, PLAU
4paraffin449.9AQP1, PLAU, MME, MYOD1, LIF
5gp 130449.9LIF, MYOD1, CXCL12
612-o-tetradecanoylphorbol 13-acetate449.9PLAU, MME, MYOD1, LIF
7actinomycin d449.9LIF, MYOD1, CXCL12, MME, PLAU
8potassium44 11 2411.9AQP1, MME, CXCL12, LIF
9azathioprine44 49 2 1112.8PLAU, MYOD1, LIF
10progesterone44 59 28 11 2413.8LIF, CXCL12, WNT10B, MME, PLAU
11creatinine449.8CAPN3, LIF, MYOD1, MME, PLAU, AQP1
12vegf449.7LIF, MYOD1, CXCL12, MME, PLAU, AQP1
13arginine449.7LIF, MYOD1, CXCL12, MME, PLAU, AQP1
14steroid449.7LIF, MYOD1, CXCL12, WNT7A, MME, PLAU
15estrogen449.7LIF, MYOD1, CXCL12, WNT7A, MME, PLAU
16serine449.6LIF, MYOD1, RRAD
17cysteine449.6AQP1, PLAU, MME, MYOD1, LIF, CAPN3
18calcium44 49 11 2411.8AQP1, CAPN3, FZD7, LIF, MYOD1, CD101

GO Terms for genes affiliated with Skeletal Muscle Regeneration

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16Gene Ontology
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Cellular components related to Skeletal Muscle Regeneration according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:0056159.6PLAU, WNT7A, WNT10B, CXCL12, LIF, TNFSF12

Biological processes related to Skeletal Muscle Regeneration according to GeneCards/GeneDecks:

(show all 11)
idNameGO IDScoreTop Affiliating Genes
1cellular response to salt stressGO:07147210.4CAPN3, AQP1
2positive regulation of satellite cell activation involved in skeletal muscle regenerationGO:01471810.3CAPN3, SOX15
3myotube differentiation involved in skeletal muscle regenerationGO:01490810.3MYOD1, BCL9
4satellite cell maintenance involved in skeletal muscle regenerationGO:01483410.3WNT7A, FZD7
5positive regulation of epithelial cell proliferation involved in wound healingGO:06005410.3WNT7A, FZD7
6somatic stem cell divisionGO:04810310.1WNT7A, FZD7
7canonical Wnt receptor signaling pathwayGO:06007010.1BCL9, WNT7A, WNT10B, FZD7
8cellular response to retinoic acidGO:07130010.1FZD7, WNT10B, AQP1
9neuron differentiationGO:0301829.9WNT7A, WNT10B, FZD7
10skeletal muscle fiber developmentGO:0487419.8MYOD1, WNT10B
11positive regulation of transcription from RNA polymerase II promoterGO:0459449.7BCL9, WNT7A, MYOD1, LIF, SOX15

Molecular functions related to Skeletal Muscle Regeneration according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1receptor agonist activityGO:04801810.2WNT7A, WNT10B
2titin bindingGO:0314329.9ACTN2, CAPN3
3receptor bindingGO:0051029.8TNFSF12, LIF, CXCL12, WNT7A
4protein bindingGO:0055158.2AQP1, CAPN3, TNFRSF12A, TNFSF12, FZD7, MYOD1

Products for genes affiliated with Skeletal Muscle Regeneration

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Sources for Skeletal Muscle Regeneration

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet