MCID: SKL007
MIFTS: 39

Skeletal Muscle Regeneration malady

Bone category

Summaries for Skeletal Muscle Regeneration

Sources:
64Wikipedia, 33MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
Wikipedia:64 Hereditary inclusion body myopathies (HIBM) are a heterogeneous group of genetic disorders which have... more...

MalaCards: Skeletal Muscle Regeneration, also known as hereditary inclusion body myopathy, is related to inclusion body myopathy 3 and frontotemporal dementia. An important gene associated with Skeletal Muscle Regeneration is WNT10B (wingless-type MMTV integration site family, member 10B), and among its related pathways are Basal cell carcinoma and Transcription Androgen Receptor nuclear signaling. The compounds matrigel and prostaglandin have been mentioned in the context of this disorder. Affiliated tissues include tongue, bone marrow and whole blood, and related mouse phenotypes are reproductive system and muscle.

Aliases & Classifications for Skeletal Muscle Regeneration

Sources:
64Wikipedia
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Bone


Aliases & Descriptions:

skeletal muscle regeneration 64
hereditary inclusion body myopathy 64


Related Diseases for Skeletal Muscle Regeneration

Sources:
17GeneCards, 18GeneDecks
See all sources

Graphical network of the top 20 diseases related to Skeletal Muscle Regeneration:



Diseases related to skeletal muscle regeneration

Clinical Features for Skeletal Muscle Regeneration

Drugs & Therapeutics for Skeletal Muscle Regeneration

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Skeletal Muscle Regeneration

Drug clinical trials:

Search ClinicalTrials for Skeletal Muscle Regeneration

Search NIH Clinical Center for Skeletal Muscle Regeneration

Search CenterWatch for Skeletal Muscle Regeneration

Genetic Tests for Skeletal Muscle Regeneration

Anatomical Context for Skeletal Muscle Regeneration

Sources:
33MalaCards
See all sources

MalaCards organs/tissues related to Skeletal Muscle Regeneration:

33
Tongue, Bone marrow, Whole blood, Skeletal muscle, Myeloid, Monocytes, T cells, B cells, Endothelial

Animal Models for Skeletal Muscle Regeneration or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
See all sources

MGI Mouse Phenotypes related to Skeletal Muscle Regeneration:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053899.7PLAU, LIF, MYOD1, AQP1, WNT7A
2MP:00053698.9CAPN3, BCL9, PLAU, RRAD, WNT10B, CXCL12
3MP:00053858.7AQP1, LIF, PLAU, RRAD, WNT7A, CAPN3

Publications for Skeletal Muscle Regeneration

Sources:
51PubMed
See all sources

Articles related to Skeletal Muscle Regeneration:

(show top 50)    (show all 247)
idTitleAuthorsYear
1
Monocyte/macrophage interactions with myogenic precursor cells during skeletal muscle regeneration. (23384231)
2013
2
Myeloid hypoxia-inducible factor-1I+ is essential for skeletal muscle regeneration in mice. (23729446)
2013
3
The time course effects of electroacupuncture on promoting skeletal muscle regeneration and inhibiting excessive fibrosis after contusion in rabbits. (23990848)
2013
4
Monocarboxylate transporter expression at the onset of skeletal muscle regeneration. (24303150)
2013
5
Heat stress promotes skeletal muscle regeneration after crush injury in rats. (24071519)
2013
6
Stem cells for skeletal muscle regeneration: therapeutic potential and roadblocks. (24299739)
2013
7
SPARC is up-regulated during skeletal muscle regeneration and inhibits myoblast differentiation. (23670848)
2013
8
Magnetic targeting of human peripheral blood CD133+ cells for skeletal muscle regeneration. (23298291)
2013
9
Genomic profiling reveals that transient adipogenic activation is a hallmark of mouse models of skeletal muscle regeneration. (23976982)
2013
10
microRNA-206 promotes skeletal muscle regeneration and delays progression of Duchenne muscular dystrophy in mice. (22546853)
2012
11
VEGF improves skeletal muscle regeneration after acute trauma and reconstruction of the limb in a rabbit model. (22806260)
2012
12
Skeletal muscle regeneration is delayed by reduction in Xin expression: consequence of impaired satellite cell activation? (21975424)
2012
13
Six1 regulates stem cell repair potential and self-renewal during skeletal muscle regeneration. (22945933)
2012
14
Rantes secreted from macrophages disturbs skeletal muscle regeneration after cardiotoxin injection in Cbl-b-deficient mice. (21254087)
2011
15
CD34 promotes satellite cell motility and entry into proliferation to facilitate efficient skeletal muscle regeneration. (21997891)
2011
16
Inhibition of plasminogen activator inhibitor-1 restores skeletal muscle regeneration in untreated type 1 diabetic mice. (21593201)
2011
17
Long-term contribution of human bone marrow mesenchymal stromal cells to skeletal muscle regeneration in mice. (20719081)
2011
18
Aligned electrospun polymer fibres for skeletal muscle regeneration. (20467965)
2010
19
Regulatory factors and cell populations involved in skeletal muscle regeneration. (20232319)
2010
20
Endometriosis-associated skeletal muscle regeneration: a hitherto undescribed entity and a potential diagnostic pitfall. (19956057)
2010
21
Sonic hedgehog regulates angiogenesis and myogenesis during post-natal skeletal muscle regeneration. (18662193)
2009
22
mTOR regulates skeletal muscle regeneration in vivo through kinase-dependent and kinase-independent mechanisms. (19794149)
2009
23
Dual and beneficial roles of macrophages during skeletal muscle regeneration. (19098520)
2009
24
Tumor necrosis factor-alpha inhibition of skeletal muscle regeneration is mediated by a caspase-dependent stem cell response. (18258721)
2008
25
Endogenous interferon-gamma is required for efficient skeletal muscle regeneration. (18353892)
2008
26
The therapeutic potential of embryonic and adult stem cells for skeletal muscle regeneration. (18607783)
2008
27
AHNAK, a novel component of the dysferlin protein complex, redistributes to the cytoplasm with dysferlin during skeletal muscle regeneration. (17185750)
2007
28
Skeletal muscle regeneration may be enhanced by overexpression of aquaporin 1 in intramuscular capillary endothelial cells. (17052860)
2007
29
Modulation of insulin-like growth factor (IGF)-I and IGF-binding protein interactions enhances skeletal muscle regeneration and ameliorates the dystrophic pathology in mdx mice. (17823291)
2007
30
Type I insulin-like growth factor receptor signaling in skeletal muscle regeneration and hypertrophy. (17947802)
2007
31
Multiple effects of high mobility group box protein 1 in skeletal muscle regeneration. (17872450)
2007
32
Increased expression of deltaCaMKII isoforms in skeletal muscle regeneration: Implications in dystrophic muscle disease. (16215994)
2006
33
Rskalpha-actin/hIGF-1 transgenic mice with increased IGF-I in skeletal muscle and blood: impact on regeneration, denervation and muscular dystrophy. (16716629)
2006
34
Macrophages and skeletal muscle regeneration: a clodronate-containing liposome depletion study. (16424086)
2006
35
Hematopoietic contribution to skeletal muscle regeneration by myelomonocytic precursors. (15353585)
2004
36
Sox15 is required for skeletal muscle regeneration. (15367664)
2004
37
A-utrophin up-regulation in mdx skeletal muscle is independent of regeneration. (14659408)
2004
38
Myogenic and nonmyogenic cells differentially express proteinases, Hsc/Hsp70, and BAG-1 during skeletal muscle regeneration. (12791605)
2003
39
The expression of dystrophin, alpha-sarcoglycan, and beta-dystroglycan during skeletal muscle regeneration: immunohistochemical and western blot studies. (12086334)
2002
40
Skeletal muscle regeneration after insulin-like growth factor I gene transfer by recombinant Sendai virus vector. (11526451)
2001
41
Skeletal muscle regeneration is not impaired in Fgf6 -/- mutant mice. (10872817)
2000
42
Fusion of myogenic cells to the newly sealed region of damaged myofibres in skeletal muscle regeneration. (8232756)
1993
43
Activation of insulin-like growth factor II expression during skeletal muscle regeneration in the rat: correlation with myotube formation. (1406701)
1992
44
Nerve-muscle interrelationships in mammalian skeletal muscle regeneration. (3045527)
1988
45
Effects of aging on skeletal muscle regeneration. (3193124)
1988
46
Skeletal muscle regeneration: a historical perspective. (3082678)
1986
47
Skeletal muscle regeneration. (7017402)
1981
48
Proceedings: Induction of skeletal muscle regeneration. (1141303)
1975
49
Skeletal-muscle regeneration. (5553469)
1971
50
A histological and histochemical study of skeletal muscle regeneration in polymyositis. (5444895)
1970

Genetic Variations for Skeletal Muscle Regeneration

Expression for genes affiliated with Skeletal Muscle Regeneration

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Skeletal Muscle Regeneration

Search GEO for disease gene expression data for Skeletal Muscle Regeneration.

Pathways for genes affiliated with Skeletal Muscle Regeneration

Sources:
30KEGG, 60Tocris Bioscience, 12EMD Millipore, 52QIAGEN, 53R&D Systems, 38NCBI BioSystems Database
See all sources

Compounds for genes affiliated with Skeletal Muscle Regeneration

Sources:
45Novoseek, 11DrugBank, 24HMDB, 50PharmGKB, 2BitterDB, 60Tocris Bioscience, 29IUPHAR
See all sources

Compounds related to Skeletal Muscle Regeneration according to GeneCards/GeneDecks:

(show all 18)
idCompoundScoreTop Affiliating Genes
1matrigel4510.1MME, CXCL12, LIF, PLAU
2prostaglandin4510.1MME, CXCL12, LIF, MYOD1
3ribonucleic acid4510.0PLAU, CXCL12, MME, LIF
4paraffin459.9MYOD1, MME, PLAU, AQP1, LIF
5gp 130459.9LIF, MYOD1, CXCL12
612-o-tetradecanoylphorbol 13-acetate459.9PLAU, MME, MYOD1, LIF
7actinomycin d459.9LIF, CXCL12, MME, PLAU, MYOD1
8potassium45 11 2411.9MME, AQP1, CXCL12, LIF
9azathioprine45 50 2 1112.8PLAU, MYOD1, LIF
10progesterone45 60 29 11 2413.8LIF, PLAU, WNT10B, MME, CXCL12
11creatinine459.8AQP1, PLAU, CAPN3, LIF, MYOD1, MME
12vegf459.7MYOD1, LIF, CXCL12, MME, PLAU, AQP1
13arginine459.7AQP1, MME, CXCL12, LIF, PLAU, MYOD1
14steroid459.7MME, PLAU, WNT7A, CXCL12, MYOD1, LIF
15estrogen459.7PLAU, MME, WNT7A, CXCL12, MYOD1, LIF
16serine459.6LIF, RRAD, MYOD1
17cysteine459.6MME, MYOD1, PLAU, CAPN3, AQP1, LIF
18calcium45 50 11 2411.8CD101, FZD7, LIF, MYOD1, AHNAK, CXCL12

GO Terms for genes affiliated with Skeletal Muscle Regeneration

Sources:
16Gene Ontology
See all sources

Cellular components related to Skeletal Muscle Regeneration according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:0056159.6PLAU, WNT7A, WNT10B, CXCL12, LIF, TNFSF12

Biological processes related to Skeletal Muscle Regeneration according to GeneCards/GeneDecks:

(show all 11)
idNameGO IDScoreTop Affiliating Genes
1cellular response to salt stressGO:07147210.4AQP1, CAPN3
2positive regulation of satellite cell activation involved in skeletal muscle regenerationGO:01471810.4SOX15, CAPN3
3satellite cell maintenance involved in skeletal muscle regenerationGO:01483410.3WNT7A, FZD7
4myotube differentiation involved in skeletal muscle regenerationGO:01490810.3MYOD1, BCL9
5positive regulation of epithelial cell proliferation involved in wound healingGO:06005410.3FZD7, WNT7A
6somatic stem cell divisionGO:04810310.1WNT7A, FZD7
7canonical Wnt receptor signaling pathwayGO:06007010.1FZD7, WNT10B, WNT7A, BCL9
8cellular response to retinoic acidGO:07130010.1AQP1, WNT10B, FZD7
9neuron differentiationGO:0301829.9WNT10B, FZD7, WNT7A
10skeletal muscle fiber developmentGO:0487419.8MYOD1, WNT10B
11positive regulation of transcription from RNA polymerase II promoterGO:0459449.7SOX15, MYOD1, WNT7A, BCL9, LIF

Molecular functions related to Skeletal Muscle Regeneration according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1receptor agonist activityGO:04801810.2WNT7A, WNT10B
2titin bindingGO:0314329.9ACTN2, CAPN3
3receptor bindingGO:0051029.8WNT7A, TNFSF12, LIF, CXCL12
4protein bindingGO:0055158.2RRAD, AHNAK, FZD7, MME, CMYA5, PLAU

Products for genes affiliated with Skeletal Muscle Regeneration

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Skeletal Muscle Regeneration

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet