Aliases & Classifications for Skin Disease

Summaries for Skin Disease

Disease Ontology : 12 An integumentary system disease that is located in skin.

MalaCards based summary : Skin Disease, also known as skin diseases, genetic, is related to epidermolysis bullosa and dermatitis herpetiformis, and has symptoms including exanthema, pruritus and enanthema. An important gene associated with Skin Disease is COL17A1 (Collagen Type XVII Alpha 1 Chain), and among its related pathways/superpathways are Developmental Biology and Keratinization. The drugs Chlorhexidine and Benzocaine have been mentioned in the context of this disorder. Affiliated tissues include skin, breast and testes, and related phenotypes are craniofacial and integument

Related Diseases for Skin Disease

Diseases related to Skin Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 303)
id Related Disease Score Top Affiliating Genes
1 epidermolysis bullosa 32.1 DSG1 FLG IL4 SPINK5
2 dermatitis herpetiformis 30.2 COL17A1 DSG1 DSG3 DST
3 lymphoma 30.2 CDSN COL17A1 DST IL4 TNF
4 squamous cell carcinoma 30.2 KRT1 KRT10
5 ichthyosis vulgaris 29.4 ABCA12 FLG KRT1 KRT14 LOR TGM1
6 granulomatous slack skin disease 11.9
7 bullous skin disease 11.9
8 vesiculobullous skin disease 11.9
9 vascular skin disease 11.7
10 degos 'en cocarde' erythrokeratoderma 11.4
11 incontinentia pigmenti 11.1
12 intellectual disability-short stature-hypertelorism syndrome 11.0 DSG1 DSG3 DST
13 psoriasis 11.0
14 acute ackee fruit intoxication 11.0 IL4 TNF
15 dermatitis, atopic 2 11.0 FLG LOR
16 transient neonatal multiple acyl-coa dehydrogenase deficiency 11.0 GJB3 GJB4
17 ligneous conjunctivitis 11.0 COL17A1 DST
18 peri-anal fistula 11.0 DSG1 DSG3 DST
19 isolated scaphocephaly 11.0 DSG1 DSG3
20 rectum carcinoma in situ 11.0 COL17A1 COL7A1 DST
21 penis agenesis 11.0 COL17A1 DST
22 autism spectrum disorder 11.0 COL17A1 DSG1 DST
23 nephrosclerosis 11.0 COL17A1 DST LAMC2
24 pilar sheath acanthoma 10.9 COL17A1 COL7A1 DST
25 pseudocholinesterase deficiency 10.9 GJB3 GJB4 LOR
26 familial nephrotic syndrome 10.9 COL7A1 DST FLG
27 jejunal somatostatinoma 10.9 COL17A1 DST LAMC2
28 peripheral t-cell lymphoma 10.9 DSG1 DSG3 DST
29 hidradenitis suppurativa 10.9
30 spermatogenic failure 18 10.9 COL7A1 FLG
31 erythrokeratodermia variabilis et progressiva 1 10.9 GJB3 GJB4 LOR
32 andersen syndrome 10.9 KRT1 KRT10
33 lip and oral cavity cancer 10.9 COL17A1 DST
34 marburg hemorrhagic fever 10.9 KRT1 KRT10
35 basidiobolomycosis 10.9 IL4 TNF
36 epidermolysis bullosa, junctional, non-herlitz type 10.9 COL17A1 COL7A1 DST LAMC2
37 acne 10.9
38 roussy-levy syndrome 10.9 LOR TGM1
39 light chain deposition disease 10.9 COL17A1 KRT14
40 ichthyosis histrix, curth-macklin type 10.9 KRT1 KRT10
41 acute pulmonary heart disease 10.9 COL17A1 DSG1 DSG3 DST
42 lagophthalmos 10.9 IL4 TNF
43 classic hairy cell leukemia 10.9 COL17A1 DSG1 DSG3 DST
44 hand dermatosis 10.9 DSG1 FLG KRT10
45 dermatitis 10.9
46 central nervous system chondroma 10.9 FLG IVL LOR
47 dyskinesia of esophagus 10.9 COL17A1 DSG1 DSG3 DST
48 churg-strauss syndrome 10.9 FLG IL4 TNF
49 urinary bladder inverted papilloma 10.9 IVL KRT14
50 uremic neuropathy 10.8 FLG KRT1 KRT10

Graphical network of the top 20 diseases related to Skin Disease:



Diseases related to Skin Disease

Symptoms & Phenotypes for Skin Disease

UMLS symptoms related to Skin Disease:


exanthema, pruritus, enanthema, skin manifestations, dry skin, nasal itching

MGI Mouse Phenotypes related to Skin Disease:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 craniofacial MP:0005382 9.5 ABCA12 COL7A1 DSG3 IL4 KRT14 LAMC2
2 integument MP:0010771 9.36 TGM1 TNF ABCA12 COL7A1 DSG3 GJB3

Drugs & Therapeutics for Skin Disease

Drugs for Skin Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 1355)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Chlorhexidine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 55-56-1 9552079 2713
2
Benzocaine Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 1994-09-7, 94-09-7 2337
3
Acitretin Approved Phase 4,Phase 3,Phase 2 55079-83-9 6437841 5284513
4
Tacrolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 104987-11-3 445643 439492
5
Metformin Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 657-24-9 14219 4091
6
Adalimumab Approved Phase 4,Phase 3,Phase 2,Phase 1 331731-18-1 16219006
7
Etanercept Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 185243-69-0
8
Infliximab Approved Phase 4,Phase 3,Phase 2,Phase 1 170277-31-3
9
Methotrexate Approved Phase 4,Phase 3,Phase 2,Phase 1 1959-05-2, 59-05-2 126941
10
Ciclopirox Approved, Investigational Phase 4,Phase 3 29342-05-0 2749
11
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 22916-47-8 4189
12
Ustekinumab Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 815610-63-0
13
Clindamycin Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 18323-44-9 29029
14
Ethanol Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 64-17-5 702
15
Phenol Approved, Experimental Phase 4 108-95-2 996
16
Glycerol Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2 56-81-5 753
17
Triamcinolone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 124-94-7 31307
18
Aminolevulinic acid Approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 106-60-5 137
19
Isotretinoin Approved Phase 4,Phase 3,Phase 2,Phase 1 4759-48-2 5538 5282379
20
Salicylic acid Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 69-72-7 338
21
Pimecrolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 137071-32-0 6447131 17753757
22
Pregabalin Approved, Illicit, Investigational Phase 4 148553-50-8 5486971
23
Fexofenadine Approved Phase 4,Phase 2,Phase 3 83799-24-0 3348
24
Gabapentin Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 60142-96-3 3446
25
Histamine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 75614-87-8, 51-45-6 774
26
Imiquimod Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 99011-02-6 57469
27
Benzoyl peroxide Approved Phase 4,Phase 3,Phase 1,Phase 2 94-36-0 7187
28
Acetylcholine Approved Phase 4,Phase 3,Phase 2,Phase 1 51-84-3 187
29
Hydroquinone Approved Phase 4,Phase 3,Phase 2,Phase 1 123-31-9 785
30
Bosentan Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 147536-97-8 104865
31
Azelaic acid Approved Phase 4,Phase 2,Phase 3,Phase 1 123-99-9 2266
32
Dimethyl fumarate Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 624-49-7 5271565 637568
33
Zinc Approved Phase 4,Phase 3,Phase 2,Phase 1 7440-66-6 32051 23994
34
Letrozole Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 112809-51-5 3902
35
Toremifene Approved, Investigational Phase 4,Phase 3,Phase 2 89778-26-7 3005573
36
Paclitaxel Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 33069-62-4 36314
37
Carboplatin Approved Phase 4,Phase 3,Phase 2,Phase 1 41575-94-4 10339178 498142 38904
38
Epirubicin Approved Phase 4,Phase 2,Phase 3,Phase 1 56420-45-2 41867
39
Anastrozole Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 120511-73-1 2187
40
Exemestane Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 107868-30-4 60198
41
Tamoxifen Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 10540-29-1 2733526
42
Zoledronic acid Approved Phase 4,Phase 2,Phase 3,Phase 1 118072-93-8 68740
43
Cyclophosphamide Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 50-18-0, 6055-19-2 2907
44
Doxorubicin Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 23214-92-8 31703
45
Fluorouracil Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 51-21-8 3385
46
Diazepam Approved, Illicit, Vet_approved Phase 4,Phase 3,Phase 2 439-14-5 3016
47
Trastuzumab Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 180288-69-1 9903
48
Bacitracin Approved, Vet_approved Phase 4,Phase 3,Phase 2 1405-87-4 439542 10909430
49
Hydrocortisone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 50-23-7 5754 657311
50
Cetirizine Approved Phase 4,Phase 3,Phase 2,Phase 1 83881-51-0 2678

Interventional clinical trials:

(show top 50) (show all 10000)

id Name Status NCT ID Phase Drugs
1 Effect of Chlorhexidine Skin Cleansing on Skin Flora Unknown status NCT00198679 Phase 4 Chlorhexidine
2 Weight Reduction Alone May Not be Sufficient to Maintain Disease Remission in Obese Patients With Psoriasis Unknown status NCT01439425 Phase 4
3 Low-Dose (17.5 mg/Day) Acitretin: Comparable Efficacy Without the Side Effects? Unknown status NCT01228409 Phase 4 Acitretin 17.5 mg/day
4 Comparison of Efficacy and Safety of 0.1% Tacrolimus and 0.1% Mometasone Furoate for Adult Vitiligo Unknown status NCT01333410 Phase 4 tacrolimus ointment;Mometasone furoate
5 Study of Efficacy of Metformin in the Treatment of Acanthosis Nigricans in Children With Obesity Unknown status NCT02438020 Phase 4 Metformin
6 Evaluation of Lymphocytic Infiltrate, Dendritic Cells and Cytokines Expression in Psoriatic Lesion and Normal Skin Before and After TNF Alfa Inhibitors Therapy Unknown status NCT01237262 Phase 4 Adalimumab, etanercept, infliximab
7 Quality of Life of Patients With Psoriasis Treated With Methotrexate: Prospective, Randomized, Double-blind, Parallel Group Study. Unknown status NCT02248792 Phase 4 Methotrexate
8 Efficacy, Safety and Cost-effectiveness of a Sequential Therapy With RV4104A Ointment, Ciclopiroxolamine Cream and Ciclopirox Film-forming Solution Compared With Amorolfine Nail Lacquer in Dermatophytic Onychomycosis Unknown status NCT01014637 Phase 4 Amorolfine (Antifungal);RV4104A, Ciclopiroxolamine, Cyclopirox (Keratolytic Agents/Antifungal)
9 Effects of Treatment With Biological Agents on Vascular and Cardiac Function in Psoriasis Unknown status NCT02144857 Phase 4 etanercept;ustekinumab;cyclosporine
10 Optimizing Psoriasis Treatment of Etanercept Combined Methotrexate Unknown status NCT02313922 Phase 4 etanercept combined with methotrexate or etanercept combined with placebo
11 A Study to Evaluate the Effectiveness of STELARA ™ (USTEKINUMAB) in the Treatment of Scalp Psoriasis Unknown status NCT01558310 Phase 4 Ustekinumab;Placebo
12 Study Evaluating the Efficacy and Safety of Triptergium Wilfordii and Acitretin in Psoriasis Vulgaris - CHINA201002016-2 Unknown status NCT01443338 Phase 4 Triptergium Wilfordii;Acitretin
13 An Open-label Study to Evaluate the Efficacy of Re-treatment for Patients With a History of Etanercept Use Unknown status NCT01132235 Phase 4
14 Combining Acitretin and Efalizumab in the Therapy of Chronic Plaque Psoriasis Unknown status NCT00707070 Phase 4 efalizumab plus placebo;efalizumab plus acitretin
15 Home UVB Phototherapy for Psoriasis: Effectiveness, Quality of Life and Cost-Effectiveness Unknown status NCT00150930 Phase 4
16 Efficacy & Safety of Clindamycin and Tretinoin in Acne Unknown status NCT01111994 Phase 4 Clindamycin Phosphate 1.2% and Tretinoin 0.025% Gel
17 Effectiveness of Lavage With Alcohol - Chlorhexidine for Chemical Matricectomy Unknown status NCT01844141 Phase 4 70% alcohol;70% alcohol - 0.5% clorhexidine
18 Efficacy of Glycerol, Two Topical Steroids, and a Topical Immune Modulator Against Skin Irritation Unknown status NCT00779792 Phase 4 clobetasol;triamcinolone acetonide;tacrolimus;glycerol;vehicle ointment (paraffin oil/soft white paraffin)
19 Superficial Basal Cell Carcinoma Treatment With Topical Photodynamic Therapy With Fractionated 5-aminolevulinic Acid 20% Versus Two Stage Methylaminolevulinate Unknown status NCT01491711 Phase 4 Methylaminolevulinate PDT in 2 sessions;Fractionated 5-aminolevulinic acid hydrochloride 20% gel PDT
20 Effect of Fluticasone Proprionate 0.05% on Narrow Band UV-B in Active Vitiligo Unknown status NCT01246921 Phase 4 Fluticasone proprionate 0.05% cream
21 Efficacy and Safety of Low-dose Oral Isotretinoin for Seborrhea Unknown status NCT01139749 Phase 4 oral isotretinoin;salicylic acid and ciclopirox olamine
22 Vitiligo and the Koebner Phenomenon (Model of Vitiligo Induction and Therapy: a Clinical and Immunological Analysis) Unknown status NCT01082393 Phase 4 topical tacrolimus treatment;topical pimecrolimus treatment;local mometasone furoate treatment;cold cream
23 Efficacy of Pregabalin in the Management of Chronic Uremic Pruritus Unknown status NCT01073501 Phase 4 Pregabalin;Placebo
24 Long Term Efficacy and Safety of Eryfotona AK-NMSC® in Patients With Actinic Keratosis Unknown status NCT01656226 Phase 4
25 Pregabalin for the Treatment of Uremic Pruritus Unknown status NCT01852318 Phase 4 pregabalin 75mg daily for 12 weeks;fexofenadine 60 mg daily for 12 weeks;placebo
26 Potential Effect of Topical Imiquimod on Atrial Ectopy in Patients With Actinic Keratosis Unknown status NCT01413763 Phase 4 Imiquimod cream 3.75%;Placebo cream
27 Clinical Study to Evaluate the Efficacy of Topical Medications Containing Benzoyl Peroxide and Sulfur in the Regression in the Short Time (24 Hours) of Moderate Acne Vulgaris Grade II (Pimples) Unknown status NCT01260571 Phase 4 Benzoyl peroxide and sulfur
28 Forehead Scars Following Mohs Micrographic Surgery and Reconstruction for Skin Cancer Unknown status NCT01459666 Phase 4 Dysport (abobotulinumtoxinA);Bacteriostatic 0.9% Sodium Chloride (vehicle)
29 Safety and Tolerability of Acanya Gel in Combination With Atralin Gel for Acne Vulgaris Unknown status NCT01448733 Phase 4 Benzoyl peroxide 2.5%/clindamycin phosphate 1.2% in the morning with with tretinoin 0.05% gel in the evening
30 A Study Comparing Combination Clindamycin Phosphate/Tretinoin Gel Alone Versus With Benzoyl Peroxide Foaming Cloths for Facial Acne Unknown status NCT01422785 Phase 4 clindamycin phosphate 1.2%/tretinoin 0.025% gel alone;clindamycin phosphate 1.2%/tretinoin 0.025% gel plus benzoyl peroxide 6% foaming cloths
31 Clinical Trial of Hydroquinone Versus Miconazol in Melasma Unknown status NCT01661556 Phase 4 Miconazole;Hydroquinone
32 The Clinical And Subclinical Effects on Arterial Stiffness of Bosentan in Patients With Systemic Sclerosis Unknown status NCT02480335 Phase 4 bosentan
33 Efficacy of Quantum NPWT With Simultaneous Irrigation on Reduction of Wound Volume in Stage III/IV Pressure Ulcers. Unknown status NCT01734109 Phase 4
34 Olive Oil's Cream Effectiveness in Prevention of Pressure Ulcers in Immobilized Patients in Primary Care Unknown status NCT01595347 Phase 4 Hyper-oxigenated fatty acid
35 Azelaic Acid Versus Hydroquinone in Melasma Unknown status NCT00927771 Phase 4 azelaic acid gel;hydroquinone cream
36 The Influence of Adalimumab on Cardiovascular and Metabolic Risk in Psoriasis Unknown status NCT01088165 Phase 4 Adalimumab treatment arm;Fumaric acid esters treatment group
37 Imiquimod 3.75% Cream in Combination With Cryotherapy in the Treatment of Hypertrophic Actinic Keratoses Unknown status NCT01229319 Phase 4 Cryotherapy alone to Left arm plus cryotherapy + imiquimod to Right arm;Cryotherapy alone to Left arm plus cryotherapy + imiquimod to Right arm
38 Extended Adjuvant Treatment With Letrozole in Breast Cancer Who Complete 5 Years of Toremifene Unknown status NCT01072318 Phase 4 Letrozole
39 Clinical Outcomes After Letrozole Treatment According to the Estrogen Receptor Expression in Postmenopausal Women Unknown status NCT01069211 Phase 4
40 Evaluation of Predictive Factors Regarding the Effectivity of Aromatase Inhibitor Therapy (PreFace) Unknown status NCT01908556 Phase 4 Letrozole
41 Safety and Efficacy of Clobetasol Propionate 0.05% E Foam in Alopecia Unknown status NCT01111981 Phase 4 Clobetasol Propionate 0.05% Emollient Foam
42 A Clinical Trial of Paclitaxel Loaded Polymeric Micelle in Patients With Taxane-Pretreated Recurrent Breast Cancer Unknown status NCT00912639 Phase 4 Paclitaxel loaded Polymeric micelle
43 Paclitaxel in Combination With Carboplatin Versus Paclitaxel Plus Epirubicin in Metastatic Breast Cancer Unknown status NCT02207361 Phase 4 Paclitaxel, Carboplatin;Paclitaxel, Epirubicin
44 Weekly and Every 3 Week Administration of Paclitaxel Liposome Injection in Metastatic Breast Cancer Unknown status NCT02142790 Phase 4 paclitaxel liposome injection
45 Circulating miRNAs as Biomarkers of Hormone Sensitivity in Breast Cancer Unknown status NCT01612871 Phase 4 Tamoxifen, Letrozole , Anastrozole, Exemestane
46 Benefits of Breast MRI for Predicting of Histopathologic Cell Type of Small Breast Cancer Unknown status NCT01597999 Phase 4
47 Clinical Trial Comparing Outcomes of Breast Conserving Operations With Classic v High-frequency Electrocoagulation Unknown status NCT01216254 Phase 4
48 Assessment of Quality of Life, Bone Density and Safety in Postmenopausal Breast Cancer Patients With Letrozole Therapy Unknown status NCT00913016 Phase 4
49 Evaluate the Relationship of Bone Remodeling Markers for Skeletal Complications in Metastatic Breast Cancer Patients Unknown status NCT00912938 Phase 4 zoledronic acid
50 Study of the Effect of Glutamine Supplementation on Chemotherapy Induced Toxicities in Breast Cancer Patients Unknown status NCT00772824 Phase 4

Search NIH Clinical Center for Skin Disease

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Skin Disease cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Skin Disease:
JACE
Embryonic/Adult Cultured Cells Related to Skin Disease:
Cultured epidermis (JACE PMIDs: 23265935 17465819 11987545

Cochrane evidence based reviews: skin diseases

Genetic Tests for Skin Disease

Genetic tests related to Skin Disease:

id Genetic test Affiliating Genes
1 Abnormality of the Skin 29

Anatomical Context for Skin Disease

MalaCards organs/tissues related to Skin Disease:

39
Skin, Breast, Testes, Lymph Node, Bone, T Cells, Brain

Publications for Skin Disease

Articles related to Skin Disease:

(show top 50) (show all 834)
id Title Authors Year
1
Long-term efficacy and tolerability of mycophenolate mofetil therapy in diffuse scleroderma skin disease. ( 28337853 )
2017
2
Knowledge, attitudes and practices towards yaws and yaws-like skin disease in Ghana. ( 28759580 )
2017
3
Preventing Occupational Skin Disease: A Review of Training Programs. ( 28509714 )
2017
4
Long-term changes in the spatial distribution of lumpy skin disease hotspots in Zimbabwe. ( 27785763 )
2017
5
Aggression and its associations in patients with skin disease. ( 28504399 )
2017
6
Mesenchymal stem cells may hold the secret to healing skin disease. ( 28297166 )
2017
7
Atopic Dermatitis, The Skin-Disease. ( 28905494 )
2017
8
Allergic Skin Disease and the Practicing Allergist: Growing Unmet Need, New Science, and New Treatments. ( 27886914 )
2017
9
Translation and Validation of the Serbian Version of the Skindex-29 Instrument for Measuring Impact of Skin Disease on Quality of Life. ( 28871926 )
2017
10
Analogs of human genetic skin disease in domesticated animals. ( 28831430 )
2017
11
Development and validation of a TaqMan probe-based real-time PCR method for the differentiation of wild type lumpy skin disease virus from vaccine virus strains. ( 28837841 )
2017
12
Antiinflammatory Activity of Cinnamon (Cinnamomum zeylanicum) Bark Essential Oil in a Human Skin Disease Model. ( 28444928 )
2017
13
Pre-control relationship of onchocercal skin disease with onchocercal infection in Guinea Savanna, Northern Nigeria. ( 28355223 )
2017
14
The Molecular Revolution in Cutaneous Biology: Identification of Skin Disease Genes. ( 28411848 )
2017
15
Two Cases of Successful Treatment of Refractory Chronic Inflammatory Skin Disease, Atopic Dermatitis and Psoriasis with Oral Alitretinoin. ( 28761307 )
2017
16
Skin biopsy in the diagnosis of neoplastic skin disease. ( 28472574 )
2017
17
Laser treatment of medical skin disease in women. ( 28831422 )
2017
18
Validation of an Egyptian Arabic Version of Skindex-16 and Quality of Life Measurement in Egyptian Patients with Skin Disease. ( 28748378 )
2017
19
Severe Mucha-Habermann-Like Ulceronecrotic Skin Disease in T-Cell Acute Lymphoblastic Leukemia Responsive to Basiliximab and Stem Cell Transplant. ( 28884915 )
2017
20
Association Between Inflammatory Skin Disease and Cardiovascular and Cerebrovascular Co-Morbidities in US Adults: Analysis of Nationwide Inpatient Sample Data. ( 28534318 )
2017
21
Contribution of health care factors to the burden of skin disease in the United States. ( 28427793 )
2017
22
Vitiligo: Not Simply a Skin Disease. ( 28528606 )
2017
23
Transmission dynamics of lumpy skin disease in Ethiopia. ( 28768560 )
2017
24
The genetic basis for most patients with pustular skin disease remains elusive. ( 28887889 )
2017
25
Skin disease in captive bats: results of an online survey of zoos and rehabilitators in Europe, North America and Australasia. ( 28044386 )
2017
26
Association between schizophrenia and an autoimmune bullous skin disease-pemphigus: a population-based large-scale study. ( 28942756 )
2017
27
Bacterial diversity in Buruli ulcer skin lesions: Challenges in the clinical microbiome analysis of a skin disease. ( 28750103 )
2017
28
The Use of Adipose-Derived Stem Cells in Selected Skin Diseases (Vitiligo, Alopecia, and Nonhealing Wounds). ( 28904532 )
2017
29
Minimal improvements in the global burden of skin disease from 1990 to 2013. ( 27986134 )
2017
30
Phenotypic analysis of circulating T-cell subset and its association with burden of skin disease in patients with chronic actinic dermatitis: a hematologic and clinicopathologic study of 20 subjects. ( 28176301 )
2017
31
Investigation on the incidence of adverse reactions, viraemia and haematological changes following field immunization of cattle using a live attenuated vaccine against lumpy skin disease. ( 28391652 )
2017
32
Lumpy skin disease in cattle: Frequency of occurrence in a dairy farm and a preliminary assessment of its possible impact on Egyptian buffaloes. ( 28397517 )
2017
33
Lumpy skin disease outbreaks in Greece during 2015-16, implementation of emergency immunization and genetic differentiation between field isolates and vaccine virus strains. ( 28284627 )
2017
34
Skin biopsy in the diagnosis of inflammatory skin disease. ( 28472573 )
2017
35
Complete Genome Sequence of Lumpy Skin Disease Virus Isolate SERBIA/Bujanovac/2016, Detected during an Outbreak in the Balkan Area. ( 28860246 )
2017
36
RIG-I antiviral signaling drives interleukin-23 production and psoriasis-like skin disease. ( 28377495 )
2017
37
Skin Disease as Art. ( 28492841 )
2017
38
Dermatology in Ghana: a retrospective review of skin disease at the Korle Bu Teaching Hospital Dermatology Clinic. ( 28533848 )
2017
39
Highlights of Skin Disease Education Foundation's 41st Annual Hawaii Dermatology Seminara8c. ( 28745729 )
2017
40
PAMs ameliorates the imiquimod-induced psoriasis-like skin disease in mice by inhibition of translocation of NF-I_B and production of inflammatory cytokines. ( 28464025 )
2017
41
Ultrasound assessment of skin thickness performed on fingers: a tool for estimating overall severity of skin disease in Systemic Sclerosis patients? ( 28917220 )
2017
42
A type of human skin dendritic cell marked by CD5 is associated with the development of inflammatory skin disease. ( 28931765 )
2017
43
Complete Genome Sequence of the Lumpy Skin Disease Virus Isolated from the First Reported Case in Greece in 2015. ( 28729259 )
2017
44
Undifferentiated pleomorphic sarcoma of the skin - a UV-induced occupational skin disease? ( 28220622 )
2017
45
Identification of unique proteomic signatures in allergic and non-allergic skin disease. ( 28703865 )
2017
46
Effective Collaboration on Skin Disease Starts With Medical Education. ( 28350601 )
2017
47
Advances in the Application and Impact of MicroRNAs as Therapies for Skin Disease. ( 28875300 )
2017
48
Occupational skin diseases from 1997 to 2004 at the Department of Dermatology, University Hospital of Northern Norway (UNN): an investigation into the course and treatment of occupational skin disease 10-15 years after first consultations with a dermatologist. ( 27172061 )
2016
49
Skin disease of penis and male genitalia is linked to atopy and circumcision: caseload in a male genital dermatology clinic. ( 27170096 )
2016
50
Therapeutic RNAi robed with ionic liquid moieties as a simple, scalable prodrug platform for treating skin disease. ( 27612407 )
2016

Variations for Skin Disease

Expression for Skin Disease

Search GEO for disease gene expression data for Skin Disease.

Pathways for Skin Disease

Pathways related to Skin Disease according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1
Show member pathways
12.95 CDSN DSG1 DSG3 FLG IVL KRT1
2
Show member pathways
11.82 CDSN DSG1 DSG3 FLG IVL KRT1
3
Show member pathways
11.47 DST KRT1 KRT14
4 11.3 IVL KRT1 KRT14

GO Terms for Skin Disease

Cellular components related to Skin Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cell junction GO:0030054 9.91 COL17A1 DSG1 DSG3 DST GJB3 GJB4
2 cell-cell junction GO:0005911 9.67 CDSN COL17A1 DSG1 GJB3
3 basement membrane GO:0005604 9.46 COL17A1 COL7A1 DST LAMC2
4 desmosome GO:0030057 9.43 CDSN DSG1 DSG3
5 hemidesmosome GO:0030056 9.4 COL17A1 DST
6 intermediate filament GO:0005882 9.35 DST FLG KRT1 KRT10 KRT14
7 epidermal lamellar body GO:0097209 9.32 ABCA12 SPINK5
8 cornified envelope GO:0001533 9.28 CDSN DSG1 DSG3 FLG IVL KRT1
9 extracellular exosome GO:0070062 10.16 CDSN DSG1 DSG3 DST IVL KRT1

Biological processes related to Skin Disease according to GeneCards Suite gene sharing:

(show all 13)
id Name GO ID Score Top Affiliating Genes
1 cell adhesion GO:0007155 9.95 CDSN COL7A1 DSG1 DSG3 DST LAMC2
2 extracellular matrix organization GO:0030198 9.8 COL7A1 LAMC2 SPINK5 TNF
3 epidermis development GO:0008544 9.77 CDSN COL17A1 COL7A1 KRT14 LAMC2
4 peptide cross-linking GO:0018149 9.73 FLG IVL KRT1 KRT10 LOR TGM1
5 keratinocyte differentiation GO:0030216 9.7 ABCA12 CDSN FLG IVL KRT10 LOR
6 skin epidermis development GO:0098773 9.62 FLG KRT1 KRT10 LOR
7 establishment of skin barrier GO:0061436 9.61 ABCA12 FLG KRT1
8 keratinization GO:0031424 9.61 ABCA12 DSG1 DSG3 IVL KRT1 KRT10
9 hemidesmosome assembly GO:0031581 9.58 COL17A1 KRT14 LAMC2
10 positive regulation of protein localization to cell surface GO:2000010 9.52 ABCA12 TNF
11 positive regulation of chemokine biosynthetic process GO:0045080 9.51 IL4 TNF
12 positive regulation of mononuclear cell migration GO:0071677 9.46 IL4 TNF
13 cornification GO:0070268 9.36 CDSN DSG1 DSG3 FLG IVL KRT1

Molecular functions related to Skin Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 structural molecule activity GO:0005198 9.26 FLG IVL KRT1 LOR
2 structural constituent of epidermis GO:0030280 8.92 FLG KRT1 KRT10 LOR

Sources for Skin Disease

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16 ExPASy
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