Aliases & Classifications for Skin Disease

Summaries for Skin Disease

Disease Ontology : 12 An integumentary system disease that is located in skin.

MalaCards based summary : Skin Disease, also known as skin diseases, genetic, is related to epidermolysis bullosa and squamous cell carcinoma, and has symptoms including exanthema, pruritus and enanthema. An important gene associated with Skin Disease is COL17A1 (Collagen Type XVII Alpha 1 Chain), and among its related pathways/superpathways are Developmental Biology and Keratinization. The drugs Chlorhexidine and Benzocaine have been mentioned in the context of this disorder. Affiliated tissues include skin, t cells and testes, and related phenotypes are craniofacial and integument

Related Diseases for Skin Disease

Diseases related to Skin Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 299)
id Related Disease Score Top Affiliating Genes
1 epidermolysis bullosa 31.4 DSG1 FLG IL4 TNF
2 squamous cell carcinoma 29.4 KRT1 KRT10 KRT14
3 granulomatous slack skin disease 12.0
4 bullous skin disease 11.9
5 vesiculobullous skin disease 11.9
6 vascular skin disease 11.7
7 incontinentia pigmenti 11.1
8 psoriasis 11.0
9 degos 'en cocarde' erythrokeratoderma 10.9
10 hidradenitis suppurativa 10.9
11 acne 10.9
12 dermatitis 10.9
13 pemphigus 10.8
14 psoriatic arthritis 10.8
15 tungiasis 10.8
16 pyoderma gangrenosum 10.8
17 keratolytic winter erythema 10.8
18 neurotic excoriation 10.7
19 lupus erythematosus 10.7
20 arthritis 10.7
21 bullous pemphigoid 10.7
22 ichthyosis 10.7
23 rosacea 10.7
24 dyskeratosis congenita 10.7
25 urticaria 10.7
26 pemphigus vulgaris 10.7
27 skin conditions 10.7
28 osteoarthritis 10.6
29 angioedema 10.6
30 rheumatoid arthritis 10.6
31 pyoderma 10.6
32 pityriasis rotunda 10.6
33 erythema multiforme 10.6
34 granuloma annulare 10.6
35 epidermolytic hyperkeratosis 10.6
36 miliaria 10.6
37 herpes gestationis 10.6
38 cellulitis 10.6
39 dowling-degos disease 1 10.6
40 keratosis palmoplantaris striata i, ad 10.5
41 fox-fordyce disease 10.5
42 myalgia-eosinophilia syndrome associated with tryptophan 10.4 DSG1 DSG3 DST
43 peripheral t-cell lymphoma 10.4 DSG1 DSG3 DST
44 atypical autism 10.4 COL17A1 DSG1 DST
45 gaucher disease, type i 10.4 FLG LOR
46 myelitis 10.4 COL17A1 DST LAMC2
47 nephrosclerosis 10.4 COL17A1 DST LAMC2
48 nephrotic syndrome, type 2 10.4 COL17A1 DST LAMC2
49 linear hamartoma syndrome 10.4 COL17A1 DST
50 pol iii-related leukodystrophies 10.4 DSG1 DSG3 DST

Graphical network of the top 20 diseases related to Skin Disease:



Diseases related to Skin Disease

Symptoms & Phenotypes for Skin Disease

UMLS symptoms related to Skin Disease:


exanthema, pruritus, enanthema, skin manifestations, dry skin, nasal itching

MGI Mouse Phenotypes related to Skin Disease:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 craniofacial MP:0005382 9.5 ABCA12 DSG3 GJB2 IL4 KRT14 LAMC2
2 integument MP:0010771 9.36 TGM1 TNF ABCA12 DSG3 GJB2 GJB3

Drugs & Therapeutics for Skin Disease

Drugs for Skin Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 1258)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Chlorhexidine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 55-56-1 9552079 2713
2
Benzocaine Approved Phase 4,Phase 3,Phase 2,Phase 1 1994-09-7, 94-09-7 2337
3
Acitretin Approved Phase 4,Phase 3,Phase 2 55079-83-9 6437841 5284513
4
Tacrolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 104987-11-3 445643 439492
5
Metformin Approved Phase 4,Phase 3,Phase 2 657-24-9 14219 4091
6
Adalimumab Approved Phase 4,Phase 3,Phase 2,Phase 1 331731-18-1 16219006
7
Etanercept Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 185243-69-0
8
Infliximab Approved Phase 4,Phase 3,Phase 2,Phase 1 170277-31-3
9
Methotrexate Approved Phase 4,Phase 3,Phase 2,Phase 1 1959-05-2, 59-05-2 126941
10
Cyclosporine Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 79217-60-0, 59865-13-3 5284373 6435893
11
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 22916-47-8 4189
12
Ustekinumab Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 815610-63-0
13
Ciclopirox Approved, Investigational Phase 4,Phase 3 29342-05-0 2749
14
Clindamycin Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 18323-44-9 29029
15
Ethanol Approved Phase 4,Phase 3,Phase 2,Phase 1 64-17-5 702
16
Phenol Approved, Experimental Phase 4,Phase 2 108-95-2 996
17
Glycerol Approved, Experimental Phase 4,Phase 3,Phase 1,Phase 2 56-81-5 753
18
Triamcinolone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 124-94-7 31307
19
Aminolevulinic acid Approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 106-60-5 137
20
Isotretinoin Approved Phase 4,Phase 3,Phase 2,Phase 1 4759-48-2 5538 5282379
21
Salicylic acid Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 69-72-7 338
22
Pimecrolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 137071-32-0 6447131 17753757
23
Pregabalin Approved, Illicit, Investigational Phase 4 148553-50-8 5486971
24
Imiquimod Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 99011-02-6 57469
25
Fexofenadine Approved Phase 4,Phase 2,Phase 3 83799-24-0 3348
26
Gabapentin Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 60142-96-3 3446
27
Histamine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 75614-87-8, 51-45-6 774
28
Benzoyl peroxide Approved Phase 4,Phase 3,Phase 1,Phase 2 94-36-0 7187
29
Acetylcholine Approved Phase 4,Phase 3,Phase 2,Phase 1 51-84-3 187
30
Hydroquinone Approved Phase 4,Phase 3,Phase 2 123-31-9 785
31
Bosentan Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 147536-97-8 104865
32
Azelaic acid Approved Phase 4,Phase 2,Phase 3,Phase 1 123-99-9 2266
33
Dimethyl fumarate Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 624-49-7 637568 5271565
34
Zinc Approved Phase 4,Phase 3,Phase 1,Phase 2 7440-66-6 32051 23994
35
Letrozole Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 112809-51-5 3902
36
Toremifene Approved, Investigational Phase 4,Phase 3,Phase 2 89778-26-7 3005573
37
Paclitaxel Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 33069-62-4 36314
38
Tetracycline Approved, Vet_approved Phase 4,Phase 2 60-54-8 5353990
39
Fluocinonide Approved, Investigational Phase 4,Early Phase 1 356-12-7 9642
40
Petrolatum Approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 8009-03-8
41
Fluocinolone Acetonide Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 1 67-73-2 6215
42
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 83-43-2 6741
43
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-24-8 5755
44
Cyclophosphamide Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 50-18-0, 6055-19-2 2907
45
Doxorubicin Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 23214-92-8 31703
46
Prednisone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 53-03-2 5865
47
Hyaluronic acid Approved, Vet_approved Phase 4,Phase 3,Phase 1 9004-61-9 53477741 24759
48
Lidocaine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 137-58-6 3676
49
Mupirocin Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 12650-69-0 446596
50
Fluorouracil Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 51-21-8 3385

Interventional clinical trials:

(show top 50) (show all 6588)
id Name Status NCT ID Phase
1 Effect of Chlorhexidine Skin Cleansing on Skin Flora Unknown status NCT00198679 Phase 4
2 Weight Reduction Alone May Not be Sufficient to Maintain Disease Remission in Obese Patients With Psoriasis Unknown status NCT01439425 Phase 4
3 Low-Dose (17.5 mg/Day) Acitretin: Comparable Efficacy Without the Side Effects? Unknown status NCT01228409 Phase 4
4 Comparison of Efficacy and Safety of 0.1% Tacrolimus and 0.1% Mometasone Furoate for Adult Vitiligo Unknown status NCT01333410 Phase 4
5 Study of Efficacy of Metformin in the Treatment of Acanthosis Nigricans in Children With Obesity Unknown status NCT02438020 Phase 4
6 Evaluation of Lymphocytic Infiltrate, Dendritic Cells and Cytokines Expression in Psoriatic Lesion and Normal Skin Before and After TNF Alfa Inhibitors Therapy Unknown status NCT01237262 Phase 4
7 Quality of Life of Patients With Psoriasis Treated With Methotrexate: Prospective, Randomized, Double-blind, Parallel Group Study. Unknown status NCT02248792 Phase 4
8 Effects of Treatment With Biological Agents on Vascular and Cardiac Function in Psoriasis Unknown status NCT02144857 Phase 4
9 Efficacy, Safety and Cost-effectiveness of a Sequential Therapy With RV4104A Ointment, Ciclopiroxolamine Cream and Ciclopirox Film-forming Solution Compared With Amorolfine Nail Lacquer in Dermatophytic Onychomycosis Unknown status NCT01014637 Phase 4
10 Optimizing Psoriasis Treatment of Etanercept Combined Methotrexate Unknown status NCT02313922 Phase 4
11 A Study to Evaluate the Effectiveness of STELARA ™ (USTEKINUMAB) in the Treatment of Scalp Psoriasis Unknown status NCT01558310 Phase 4
12 Study Evaluating the Efficacy and Safety of Triptergium Wilfordii and Acitretin in Psoriasis Vulgaris - CHINA201002016-2 Unknown status NCT01443338 Phase 4
13 An Open-label Study to Evaluate the Efficacy of Re-treatment for Patients With a History of Etanercept Use Unknown status NCT01132235 Phase 4
14 Combining Acitretin and Efalizumab in the Therapy of Chronic Plaque Psoriasis Unknown status NCT00707070 Phase 4
15 Home UVB Phototherapy for Psoriasis: Effectiveness, Quality of Life and Cost-Effectiveness Unknown status NCT00150930 Phase 4
16 Efficacy & Safety of Clindamycin and Tretinoin in Acne Unknown status NCT01111994 Phase 4
17 Effectiveness of Lavage With Alcohol - Chlorhexidine for Chemical Matricectomy Unknown status NCT01844141 Phase 4
18 Efficacy of Glycerol, Two Topical Steroids, and a Topical Immune Modulator Against Skin Irritation Unknown status NCT00779792 Phase 4
19 Superficial Basal Cell Carcinoma Treatment With Topical Photodynamic Therapy With Fractionated 5-aminolevulinic Acid 20% Versus Two Stage Methylaminolevulinate Unknown status NCT01491711 Phase 4
20 Effect of Fluticasone Proprionate 0.05% on Narrow Band UV-B in Active Vitiligo Unknown status NCT01246921 Phase 4
21 Efficacy and Safety of Low-dose Oral Isotretinoin for Seborrhea Unknown status NCT01139749 Phase 4
22 Vitiligo and the Koebner Phenomenon (Model of Vitiligo Induction and Therapy: a Clinical and Immunological Analysis) Unknown status NCT01082393 Phase 4
23 Efficacy of Pregabalin in the Management of Chronic Uremic Pruritus Unknown status NCT01073501 Phase 4
24 Imiquimod Versus Photodynamic Therapy of Actinic Keratoses in Organ Transplant Recipients Unknown status NCT01538901 Phase 4
25 Long Term Efficacy and Safety of Eryfotona AK-NMSC® in Patients With Actinic Keratosis Unknown status NCT01656226 Phase 4
26 Pregabalin for the Treatment of Uremic Pruritus Unknown status NCT01852318 Phase 4
27 Potential Effect of Topical Imiquimod on Atrial Ectopy in Patients With Actinic Keratosis Unknown status NCT01413763 Phase 4
28 Clinical Study to Evaluate the Efficacy of Topical Medications Containing Benzoyl Peroxide and Sulfur in the Regression in the Short Time (24 Hours) of Moderate Acne Vulgaris Grade II (Pimples) Unknown status NCT01260571 Phase 4
29 Forehead Scars Following Mohs Micrographic Surgery and Reconstruction for Skin Cancer Unknown status NCT01459666 Phase 4
30 Safety and Tolerability of Acanya Gel in Combination With Atralin Gel for Acne Vulgaris Unknown status NCT01448733 Phase 4
31 A Study Comparing Combination Clindamycin Phosphate/Tretinoin Gel Alone Versus With Benzoyl Peroxide Foaming Cloths for Facial Acne Unknown status NCT01422785 Phase 4
32 Clinical Trial of Hydroquinone Versus Miconazol in Melasma Unknown status NCT01661556 Phase 4
33 The Clinical And Subclinical Effects on Arterial Stiffness of Bosentan in Patients With Systemic Sclerosis Unknown status NCT02480335 Phase 4
34 Efficacy of Quantum NPWT With Simultaneous Irrigation on Reduction of Wound Volume in Stage III/IV Pressure Ulcers. Unknown status NCT01734109 Phase 4
35 Olive Oil's Cream Effectiveness in Prevention of Pressure Ulcers in Immobilized Patients in Primary Care Unknown status NCT01595347 Phase 4
36 Azelaic Acid Versus Hydroquinone in Melasma Unknown status NCT00927771 Phase 4
37 The Influence of Adalimumab on Cardiovascular and Metabolic Risk in Psoriasis Unknown status NCT01088165 Phase 4
38 Imiquimod 3.75% Cream in Combination With Cryotherapy in the Treatment of Hypertrophic Actinic Keratoses Unknown status NCT01229319 Phase 4
39 Extended Adjuvant Treatment With Letrozole in Breast Cancer Who Complete 5 Years of Toremifene Unknown status NCT01072318 Phase 4
40 Clinical Outcomes After Letrozole Treatment According to the Estrogen Receptor Expression in Postmenopausal Women Unknown status NCT01069211 Phase 4
41 Evaluation of Predictive Factors Regarding the Effectivity of Aromatase Inhibitor Therapy (PreFace) Unknown status NCT01908556 Phase 4
42 Safety and Efficacy of Clobetasol Propionate 0.05% E Foam in Alopecia Unknown status NCT01111981 Phase 4
43 A Clinical Trial of Paclitaxel Loaded Polymeric Micelle in Patients With Taxane-Pretreated Recurrent Breast Cancer Unknown status NCT00912639 Phase 4
44 Randomised Double Blind Crossover Placebo Controlled Study to Evaluate the Efficacy of Tetracycline in Epidermolysis Bullosa Unknown status NCT00336154 Phase 4
45 VANOS Cream and Skin Barrier Function Unknown status NCT00819507 Phase 4
46 Effect of Moisturizing Creams on Skin Barrier Function Unknown status NCT00771121 Phase 4
47 Punchgrafting Techniques for Vitiligo Unknown status NCT01377077 Phase 4
48 Efficacy of KAM2904 Face Cream and KAM3008 Body Lotion Treatment in Children With Atopic Dermatitis (AD) Unknown status NCT01781663 Phase 4
49 Flucinolone Acetonide Implant for Treating Refractory Ocular Behcet's Disease Unknown status NCT00720928 Phase 4
50 The Efficacy of Methylprednisolone in the Treatment of Patients With Ocular Involvement in Behcet's Disease Unknown status NCT01306955 Phase 4

Search NIH Clinical Center for Skin Disease

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Skin Disease cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Skin Disease:
JACE
Embryonic/Adult Cultured Cells Related to Skin Disease:
Cultured epidermis (JACE PMIDs: 23265935 17465819 11987545

Cochrane evidence based reviews: skin diseases

Genetic Tests for Skin Disease

Genetic tests related to Skin Disease:

id Genetic test Affiliating Genes
1 Abnormality of the Skin 29

Anatomical Context for Skin Disease

MalaCards organs/tissues related to Skin Disease:

39
Skin, T Cells, Testes, Neutrophil, Endothelial, Bone, Eye

The Foundational Model of Anatomy Ontology organs/tissues related to Skin Disease:

18
Skin

Publications for Skin Disease

Articles related to Skin Disease:

(show top 50) (show all 810)
id Title Authors Year
1
Preventing Occupational Skin Disease: A Review of Training Programs. ( 28509714 )
2017
2
Skin Disease as Art. ( 28492841 )
2017
3
The Molecular Revolution in Cutaneous Biology: Identification of Skin Disease Genes. ( 28411848 )
2017
4
Effective Collaboration on Skin Disease Starts With Medical Education. ( 28350601 )
2017
5
Contribution of health care factors to the burden of skin disease in the United States. ( 28427793 )
2017
6
Long-term changes in the spatial distribution of lumpy skin disease hotspots in Zimbabwe. ( 27785763 )
2017
7
Lumpy skin disease in cattle: Frequency of occurrence in a dairy farm and a preliminary assessment of its possible impact on Egyptian buffaloes. ( 28397517 )
2017
8
RIG-I antiviral signaling drives interleukin-23 production and psoriasis-like skin disease. ( 28377495 )
2017
9
Minimal improvements in the global burden of skin disease from 1990 to 2013. ( 27986134 )
2017
10
PAMs ameliorates the imiquimod-induced psoriasis-like skin disease in mice by inhibition of translocation of NF-I_B and production of inflammatory cytokines. ( 28464025 )
2017
11
Vitiligo: Not Simply a Skin Disease. ( 28528606 )
2017
12
Antiinflammatory Activity of Cinnamon (Cinnamomum zeylanicum) Bark Essential Oil in a Human Skin Disease Model. ( 28444928 )
2017
13
Pre-control relationship of onchocercal skin disease with onchocercal infection in Guinea Savanna, Northern Nigeria. ( 28355223 )
2017
14
Association Between Inflammatory Skin Disease and Cardiovascular and Cerebrovascular Co-Morbidities in US Adults: Analysis of Nationwide Inpatient Sample Data. ( 28534318 )
2017
15
Lumpy skin disease outbreaks in Greece during 2015-16, implementation of emergency immunization and genetic differentiation between field isolates and vaccine virus strains. ( 28284627 )
2017
16
Long-term efficacy and tolerability of mycophenolate mofetil therapy in diffuse scleroderma skin disease. ( 28337853 )
2017
17
Mesenchymal stem cells may hold the secret to healing skin disease. ( 28297166 )
2017
18
Skin disease in captive bats: results of an online survey of zoos and rehabilitators in Europe, North America and Australasia. ( 28044386 )
2017
19
Skin biopsy in the diagnosis of inflammatory skin disease. ( 28472573 )
2017
20
Dermatology in Ghana: a retrospective review of skin disease at the Korle Bu Teaching Hospital Dermatology Clinic. ( 28533848 )
2017
21
Investigation on the incidence of adverse reactions, viraemia and haematological changes following field immunization of cattle using a live attenuated vaccine against lumpy skin disease. ( 28391652 )
2017
22
Allergic Skin Disease and the Practicing Allergist: Growing Unmet Need, New Science, and New Treatments. ( 27886914 )
2017
23
Skin biopsy in the diagnosis of neoplastic skin disease. ( 28472574 )
2017
24
Aggression and its associations in patients with skin disease. ( 28504399 )
2017
25
Benign skin disease with pustules in the newborn. ( 27192509 )
2016
26
Vaccination against lumpy skin disease started in Bulgaria. ( 27179082 )
2016
27
The expanding role of methotrexate for treating skin disease. ( 27484263 )
2016
28
Use of mycophenolate mofetil to treat immune-mediated skin disease in 14 dogs - a retrospective evaluation. ( 27943548 )
2016
29
Rapid, noninvasive quantitation of skin disease in systemic sclerosis using optical coherence elastography. ( 27048877 )
2016
30
Treatment with DHA/EPA ameliorates atopic dermatitis-like skin disease by blocking LTB4 production. ( 27644556 )
2016
31
Epizootology and Molecular Diagnosis of Lumpy Skin Disease among Livestock in Azerbaijan. ( 27446057 )
2016
32
Necrolytic acral erythema: a rare skin disease associated with hepatitis C virus infection. ( 27828642 )
2016
33
Occupational skin diseases from 1997 to 2004 at the Department of Dermatology, University Hospital of Northern Norway (UNN): an investigation into the course and treatment of occupational skin disease 10-15 years after first consultations with a dermatologist. ( 27172061 )
2016
34
Emergence of Lumpy Skin Disease in Greece, 2015. ( 26991342 )
2016
35
Skin disease of penis and male genitalia is linked to atopy and circumcision: caseload in a male genital dermatology clinic. ( 27170096 )
2016
36
Spatial and Temporal Epidemiology of Lumpy Skin Disease in the Middle East, 2012-2015. ( 26973845 )
2016
37
Skin disease and thyroid autoimmunity in atopic South Italian children. ( 27610344 )
2016
38
Awareness of occupational skin disease in the service sector. ( 27402950 )
2016
39
Serum Malassezia-specific IgE in dogs with recurrent Malassezia otitis externa without concurrent skin disease. ( 27288851 )
2016
40
The x-ray crystal structure of the keratin 1-keratin 10 helix 2B heterodimer reveals molecular surface properties and biochemical insights into human skin disease. ( 27595935 )
2016
41
Occupational skin disease among Australian healthcare workers: a retrospective analysis from an occupational dermatology clinic, 1993-2014. ( 27436328 )
2016
42
Skin Disease in the Uninsured: Diagnoses, Management Decisions, and Referral Outcomes of an Urban Free Clinic. ( 27180711 )
2016
43
A case of alopecia as IgG4-related skin disease. ( 27846747 )
2016
44
IgG4-related skin disease may have distinct systemic manifestations: a systematic review. ( 27419384 )
2016
45
Non-infectious environmental antigens as a trigger for the initiation of an autoimmune skin disease. ( 27396816 )
2016
46
Lipidomic analysis of epidermal lipids: a tool to predict progression of inflammatory skin disease in humans. ( 27121756 )
2016
47
Measuring the impact of skin disease on children's quality of life. ( 27115588 )
2016
48
CD1a on Langerhans cells controls inflammatory skin disease. ( 27548435 )
2016
49
British Association of Dermatologists' guidelines for the safe and effective prescribing of methotrexate for skin disease 2016. ( 27484275 )
2016
50
Complete Genome Sequences of the Neethling-Like Lumpy Skin Disease Virus Strains Obtained Directly from Three Commercial Live Attenuated Vaccines. ( 27834707 )
2016

Variations for Skin Disease

Expression for Skin Disease

Search GEO for disease gene expression data for Skin Disease.

Pathways for Skin Disease

GO Terms for Skin Disease

Cellular components related to Skin Disease according to GeneCards Suite gene sharing:

(show all 12)
id Name GO ID Score Top Affiliating Genes
1 cell junction GO:0030054 9.87 COL17A1 DSG1 DSG3 DST GJB2 GJB3
2 cell-cell junction GO:0005911 9.73 CDSN COL17A1 DSG1 GJB3
3 basement membrane GO:0005604 9.69 COL17A1 DST LAMC2
4 gap junction GO:0005921 9.54 GJB2 GJB3 GJB4
5 hemidesmosome GO:0030056 9.46 COL17A1 DST
6 desmosome GO:0030057 9.43 CDSN DSG1 DSG3
7 epidermal lamellar body GO:0097209 9.4 ABCA12 SPINK5
8 intermediate filament GO:0005882 9.35 DST FLG KRT1 KRT10 KRT14
9 connexin complex GO:0005922 9.33 GJB2 GJB3 GJB4
10 cornified envelope GO:0001533 9.28 CDSN DSG1 DSG3 FLG IVL KRT1
11 cytosol GO:0005829 10.29 ABCA12 DSG1 DSG3 DST FLG GJB2
12 extracellular exosome GO:0070062 10.19 CDSN DSG1 DSG3 DST IVL KRT1

Biological processes related to Skin Disease according to GeneCards Suite gene sharing:

(show all 12)
id Name GO ID Score Top Affiliating Genes
1 epidermis development GO:0008544 9.73 CDSN COL17A1 KRT14 LAMC2
2 peptide cross-linking GO:0018149 9.73 FLG IVL KRT1 KRT10 LOR TGM1
3 keratinocyte differentiation GO:0030216 9.7 ABCA12 CDSN FLG IVL KRT10 LOR
4 cell communication GO:0007154 9.65 GJB2 GJB3 GJB4
5 skin epidermis development GO:0098773 9.62 FLG KRT1 KRT10 LOR
6 keratinization GO:0031424 9.61 ABCA12 DSG1 DSG3 IVL KRT1 KRT10
7 establishment of skin barrier GO:0061436 9.58 ABCA12 FLG KRT1
8 hemidesmosome assembly GO:0031581 9.54 COL17A1 KRT14 LAMC2
9 positive regulation of protein localization to cell surface GO:2000010 9.51 ABCA12 TNF
10 positive regulation of chemokine biosynthetic process GO:0045080 9.49 IL4 TNF
11 positive regulation of mononuclear cell migration GO:0071677 9.46 IL4 TNF
12 cornification GO:0070268 9.36 CDSN DSG1 DSG3 FLG IVL KRT1

Molecular functions related to Skin Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 structural molecule activity GO:0005198 9.26 FLG IVL KRT1 LOR
2 gap junction channel activity GO:0005243 9.16 GJB2 GJB3
3 structural constituent of epidermis GO:0030280 8.92 FLG KRT1 KRT10 LOR

Sources for Skin Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....