Aliases & Classifications for Skin Disease

Summaries for Skin Disease

Disease Ontology : 12 An integumentary system disease that is located in skin.

MalaCards based summary : Skin Disease, also known as skin diseases, genetic, is related to bullous skin disease and vesiculobullous skin disease, and has symptoms including pruritus, exanthema and nasal itching. An important gene associated with Skin Disease is COL17A1 (Collagen Type XVII Alpha 1 Chain), and among its related pathways/superpathways are Developmental Biology and Keratinization. The drugs Chlorhexidine and Benzocaine have been mentioned in the context of this disorder. Affiliated tissues include skin, skin and breast, and related phenotypes are craniofacial and integument

Related Diseases for Skin Disease

Diseases related to Skin Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 328)
# Related Disease Score Top Affiliating Genes
1 bullous skin disease 33.9 COL17A1 DSG1 DSG3 DST
2 vesiculobullous skin disease 33.7 COL17A1 COL7A1 DST KRT14 LAMC2
3 hidradenitis suppurativa 32.3 KRT10 KRT14 TNF
4 neurotic excoriation 32.3 COL17A1 COL7A1 DST
5 pemphigus 32.2 COL17A1 DSG1 DSG3 DST
6 dermatitis 32.2 DSG1 FLG IL4 SPINK5
7 tungiasis 32.2 IL4 TNF
8 epidermolytic hyperkeratosis 31.9 FLG KRT1 KRT10 LOR
9 epidermolysis bullosa 31.8 COL17A1 COL7A1 DST KRT14 LAMC2
10 bullous pemphigoid 31.8 COL17A1 DSG1 DSG3 DST IVL LAMC2
11 dermatitis, atopic 31.8 FLG IL4 IVL LOR SPINK5 TNF
12 pemphigoid gestationis 31.6 COL17A1 DST
13 cicatricial pemphigoid 31.5 COL17A1 DST LAMC2
14 white sponge nevus 1 31.3 KRT1 KRT10 KRT14
15 psoriasis 31.3 CDSN FLG IL4 IVL KRT1 KRT10
16 contact dermatitis 31.3 FLG IL4 TNF
17 keratosis 31.3 FLG IVL KRT1 KRT10
18 ichthyosis 31.3 ABCA12 FLG KRT1 KRT10 LOR SPINK5
19 allergic contact dermatitis 31.2 FLG IL4 TNF
20 pemphigus vulgaris 30.2 DSG1 DSG3 DST
21 hidradenitis 30.1 KRT10 KRT14 TNF
22 ige responsiveness, atopic 30.1 FLG IL4 SPINK5
23 pemphigus foliaceus 30.0 DSG1 DSG3 DST
24 striate palmoplantar keratoderma 29.9 DSG1 KRT1 KRT10 KRT14
25 netherton syndrome 29.9 DSG1 FLG SPINK5 TGM1
26 erythrokeratodermia variabilis et progressiva 1 29.9 GJB3 GJB4 LOR
27 paraneoplastic pemphigus 29.9 COL17A1 DSG1 DSG3 DST
28 ichthyosis, congenital, autosomal recessive 4b 29.7 ABCA12 FLG TGM1
29 vohwinkel syndrome 29.7 LOR TGM1
30 autoimmune disease 29.6 COL17A1 DSG1 IL4 TNF
31 basal cell carcinoma 29.5 COL17A1 IVL KRT10 KRT14 LAMC2
32 ichthyosis vulgaris 29.3 ABCA12 FLG KRT1 KRT14 LOR TGM1
33 granulomatous slack skin disease 12.1
34 vascular skin disease 11.8
35 degos 'en cocarde' erythrokeratoderma 11.5
36 keratolytic winter erythema 11.4
37 incontinentia pigmenti 11.2
38 neurofibromatosis, type ii 11.0
39 psoriatic arthritis 10.9
40 pyoderma gangrenosum 10.9
41 arthritis 10.8
42 lupus erythematosus 10.8
43 vitiligo-associated multiple autoimmune disease susceptibility 1 10.8
44 onchocerciasis 10.8
45 rosacea 10.8
46 dyskeratosis congenita 10.8
47 pemphigus vulgaris, familial 10.7
48 skin conditions 10.7
49 urticaria 10.7
50 rheumatoid arthritis 10.7

Graphical network of the top 20 diseases related to Skin Disease:



Diseases related to Skin Disease

Symptoms & Phenotypes for Skin Disease

UMLS symptoms related to Skin Disease:


pruritus, exanthema, nasal itching, dry skin, skin manifestations, enanthema

MGI Mouse Phenotypes related to Skin Disease:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 craniofacial MP:0005382 9.5 IL4 KRT14 LAMC2 TNF ABCA12 COL7A1
2 integument MP:0010771 9.4 KRT1 KRT14 LAMC2 SPINK5 TGM1 TNF

Drugs & Therapeutics for Skin Disease

Drugs for Skin Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 1348)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Chlorhexidine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 55-56-1 2713 9552079
2
Benzocaine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 1994-09-7, 94-09-7 2337
3
Acitretin Approved Phase 4,Phase 3,Phase 2 55079-83-9 5284513 6437841
4
Tacrolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 104987-11-3 445643 439492
5
Metformin Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 657-24-9 4091 14219
6
Ethanol Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 64-17-5 702
7
Petrolatum Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 8009-03-8
8 Titanium dioxide Approved Phase 4,Phase 2 13463-67-7
9
Ustekinumab Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 815610-63-0
10
Desonide Approved, Investigational Phase 4,Phase 3 638-94-8 5311066
11
Esomeprazole Approved, Investigational Phase 4,Phase 1 161796-78-7, 119141-88-7 9579578 4594
12
Etanercept Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 185243-69-0
13
Methotrexate Approved Phase 4,Phase 3,Phase 2,Phase 1 1959-05-2, 59-05-2 126941
14
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 22916-47-8 4189
15
Ciclopirox Approved, Investigational Phase 4,Phase 3 29342-05-0 2749
16
Adalimumab Approved Phase 4,Phase 3,Phase 2,Phase 1 331731-18-1 16219006
17
Infliximab Approved Phase 4,Phase 3,Phase 2,Phase 1 170277-31-3
18
Phenol Approved, Experimental Phase 4 108-95-2 996
19
Clindamycin Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 18323-44-9 29029
20
Clobetasol Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 25122-41-2, 25122-46-7 5311051 32798
21
Glycerol Approved, Investigational Phase 4,Phase 3,Phase 1 56-81-5 753
22
Triamcinolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 124-94-7 31307
23
Aminolevulinic acid Approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 106-60-5 137
24
Isotretinoin Approved Phase 4,Phase 3,Phase 2,Phase 1 4759-48-2 5282379 5538
25
Salicylic acid Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 69-72-7 338
26
Fexofenadine Approved, Investigational Phase 4,Phase 2 83799-24-0 3348
27
Gabapentin Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 60142-96-3 3446
28
Histamine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 51-45-6, 75614-87-8 774
29
Pregabalin Approved, Illicit, Investigational Phase 4 148553-50-8 5486971
30
Imiquimod Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 99011-02-6 57469
31
Alginic acid Approved, Experimental, Investigational Phase 4,Phase 3 9005-32-7
32
Benzoyl peroxide Approved Phase 4,Phase 3,Phase 1,Phase 2 94-36-0 7187
33
Bosentan Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 147536-97-8 104865
34
Hydroquinone Approved, Investigational Phase 4,Phase 3,Phase 2 123-31-9 785
35
Acetylcholine Approved Phase 4,Phase 3,Phase 2,Phase 1 51-84-3 187
36
Pimecrolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 137071-32-0 17753757 6447131
37
Azelaic acid Approved Phase 4,Phase 2,Phase 3,Phase 1 123-99-9 2266
38
Menthol Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 2216-51-5 16666
39
Zinc Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 7440-66-6 32051 23994
40
Zinc oxide Approved Phase 4,Phase 3,Phase 2 1314-13-2
41
Iron Approved Phase 4,Phase 3,Phase 2,Early Phase 1 7439-89-6 23925
42
Iodine Approved, Investigational Phase 4,Phase 2,Phase 1,Early Phase 1 7553-56-2 807
43
Povidone Approved Phase 4,Phase 3,Phase 2 9003-39-8
44
Povidone-iodine Approved Phase 4,Phase 3 25655-41-8
45
Carboplatin Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 41575-94-4 10339178 38904 498142
46
Epirubicin Approved Phase 4,Phase 3,Phase 2,Phase 1 56420-45-2 41867
47
Paclitaxel Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 33069-62-4 36314
48
Letrozole Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 112809-51-5 3902
49
Anastrozole Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 120511-73-1 2187
50
Exemestane Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 107868-30-4 60198

Interventional clinical trials:

(show top 50) (show all 10000)

# Name Status NCT ID Phase Drugs
1 Effect of Chlorhexidine Skin Cleansing on Skin Flora Unknown status NCT00198679 Phase 4 Chlorhexidine
2 Weight Reduction Alone May Not be Sufficient to Maintain Disease Remission in Obese Patients With Psoriasis Unknown status NCT01439425 Phase 4
3 Low-Dose (17.5 mg/Day) Acitretin: Comparable Efficacy Without the Side Effects? Unknown status NCT01228409 Phase 4 Acitretin 17.5 mg/day
4 Comparison of Efficacy and Safety of 0.1% Tacrolimus and 0.1% Mometasone Furoate for Adult Vitiligo Unknown status NCT01333410 Phase 4 tacrolimus ointment;Mometasone furoate
5 Study of Efficacy of Metformin in the Treatment of Acanthosis Nigricans in Children With Obesity Unknown status NCT02438020 Phase 4 Metformin
6 Mometasone Furoate Cream Reduces Acute Radiation Dermatitis in Head and Neck Squamous Cell Carcinomas' Patients Unknown status NCT02495064 Phase 4 Mometasone Furoate Cream
7 The Difference of Microparticles in Patients With Psoriasis Vulgaris Who Received Stelara(Ustekinumab) Unknown status NCT02693470 Phase 4 Ustekinumab
8 Proton Pump Inhibitors Use in Patients With Psoriasis Unknown status NCT02624544 Phase 4 esomeprazole;desonide
9 Optimizing Psoriasis Treatment of Etanercept Combined Methotrexate Unknown status NCT02313922 Phase 4 etanercept combined with methotrexate or etanercept combined with placebo
10 Quality of Life of Patients With Psoriasis Treated With Methotrexate: Prospective, Randomized, Double-blind, Parallel Group Study. Unknown status NCT02248792 Phase 4 Methotrexate
11 Effects of Treatment With Biological Agents on Vascular and Cardiac Function in Psoriasis Unknown status NCT02144857 Phase 4 etanercept;ustekinumab;cyclosporine
12 A Study to Evaluate the Effectiveness of STELARA ™ (USTEKINUMAB) in the Treatment of Scalp Psoriasis Unknown status NCT01558310 Phase 4 Ustekinumab;Placebo
13 Study Evaluating the Efficacy and Safety of Triptergium Wilfordii and Acitretin in Psoriasis Vulgaris - CHINA201002016-2 Unknown status NCT01443338 Phase 4 Triptergium Wilfordii;Acitretin
14 Efficacy, Safety and Cost-effectiveness of a Sequential Therapy With RV4104A Ointment, Ciclopiroxolamine Cream and Ciclopirox Film-forming Solution Compared With Amorolfine Nail Lacquer in Dermatophytic Onychomycosis Unknown status NCT01014637 Phase 4 Amorolfine (Antifungal);RV4104A, Ciclopiroxolamine, Cyclopirox (Keratolytic Agents/Antifungal)
15 Evaluation of Lymphocytic Infiltrate, Dendritic Cells and Cytokines Expression in Psoriatic Lesion and Normal Skin Before and After TNF Alfa Inhibitors Therapy Unknown status NCT01237262 Phase 4 Adalimumab, etanercept, infliximab
16 An Open-label Study to Evaluate the Efficacy of Re-treatment for Patients With a History of Etanercept Use Unknown status NCT01132235 Phase 4
17 Combining Acitretin and Efalizumab in the Therapy of Chronic Plaque Psoriasis Unknown status NCT00707070 Phase 4 efalizumab plus placebo;efalizumab plus acitretin
18 Home UVB Phototherapy for Psoriasis: Effectiveness, Quality of Life and Cost-Effectiveness Unknown status NCT00150930 Phase 4
19 Epidermal Grafting in Wound Healing Unknown status NCT02535481 Phase 4
20 Effectiveness of Lavage With Alcohol - Chlorhexidine for Chemical Matricectomy Unknown status NCT01844141 Phase 4 70% alcohol;70% alcohol - 0.5% clorhexidine
21 Efficacy & Safety of Clindamycin and Tretinoin in Acne Unknown status NCT01111994 Phase 4 Clindamycin Phosphate 1.2% and Tretinoin 0.025% Gel
22 Efficacy of Glycerol, Two Topical Steroids, and a Topical Immune Modulator Against Skin Irritation Unknown status NCT00779792 Phase 4 clobetasol;triamcinolone acetonide;tacrolimus;glycerol;vehicle ointment (paraffin oil/soft white paraffin)
23 Superficial Basal Cell Carcinoma Treatment With Topical Photodynamic Therapy With Fractionated 5-aminolevulinic Acid 20% Versus Two Stage Methylaminolevulinate Unknown status NCT01491711 Phase 4 Methylaminolevulinate PDT in 2 sessions;Fractionated 5-aminolevulinic acid hydrochloride 20% gel PDT
24 Efficacy and Safety of Low-dose Oral Isotretinoin for Seborrhea Unknown status NCT01139749 Phase 4 oral isotretinoin;salicylic acid and ciclopirox olamine
25 Efficacy and Safety of Treatment of Actinic Keratoses With Photodynamic Therapy Between MAL Cream and ALA Gel Unknown status NCT02647151 Phase 4 METHYLAMINOLEVULINATE HYDROCHLORIDE;AMINOLEVULINIC ACID HYDROCHLORIDE
26 Pregabalin for the Treatment of Uremic Pruritus Unknown status NCT01852318 Phase 4 pregabalin 75mg daily for 12 weeks;fexofenadine 60 mg daily for 12 weeks;placebo
27 Long Term Efficacy and Safety of Eryfotona AK-NMSC® in Patients With Actinic Keratosis Unknown status NCT01656226 Phase 4
28 Potential Effect of Topical Imiquimod on Atrial Ectopy in Patients With Actinic Keratosis Unknown status NCT01413763 Phase 4 Imiquimod cream 3.75%;Placebo cream
29 Efficacy of Pregabalin in the Management of Chronic Uremic Pruritus Unknown status NCT01073501 Phase 4 Pregabalin;Placebo
30 Leptospermum Scoparium Honey and Wound Care for Pressure Ulcers Unknown status NCT02689310 Phase 4
31 Safety and Tolerability of Acanya Gel in Combination With Atralin Gel for Acne Vulgaris Unknown status NCT01448733 Phase 4 Benzoyl peroxide 2.5%/clindamycin phosphate 1.2% in the morning with with tretinoin 0.05% gel in the evening
32 A Study Comparing Combination Clindamycin Phosphate/Tretinoin Gel Alone Versus With Benzoyl Peroxide Foaming Cloths for Facial Acne Unknown status NCT01422785 Phase 4 clindamycin phosphate 1.2%/tretinoin 0.025% gel alone;clindamycin phosphate 1.2%/tretinoin 0.025% gel plus benzoyl peroxide 6% foaming cloths
33 The Clinical And Subclinical Effects on Arterial Stiffness of Bosentan in Patients With Systemic Sclerosis Unknown status NCT02480335 Phase 4 bosentan
34 Clinical Study to Evaluate the Efficacy of Topical Medications Containing Benzoyl Peroxide and Sulfur in the Regression in the Short Time (24 Hours) of Moderate Acne Vulgaris Grade II (Pimples) Unknown status NCT01260571 Phase 4 Benzoyl peroxide and sulfur
35 Efficacy of Quantum NPWT With Simultaneous Irrigation on Reduction of Wound Volume in Stage III/IV Pressure Ulcers. Unknown status NCT01734109 Phase 4
36 Clinical Trial of Hydroquinone Versus Miconazol in Melasma Unknown status NCT01661556 Phase 4 Miconazole;Hydroquinone
37 Olive Oil's Cream Effectiveness in Prevention of Pressure Ulcers in Immobilized Patients in Primary Care Unknown status NCT01595347 Phase 4 Hyper-oxigenated fatty acid
38 Forehead Scars Following Mohs Micrographic Surgery and Reconstruction for Skin Cancer Unknown status NCT01459666 Phase 4 Dysport (abobotulinumtoxinA);Bacteriostatic 0.9% Sodium Chloride (vehicle)
39 Effect of Fluticasone Proprionate 0.05% on Narrow Band UV-B in Active Vitiligo Unknown status NCT01246921 Phase 4 Fluticasone proprionate 0.05% cream
40 Vitiligo and the Koebner Phenomenon (Model of Vitiligo Induction and Therapy: a Clinical and Immunological Analysis) Unknown status NCT01082393 Phase 4 topical tacrolimus treatment;topical pimecrolimus treatment;local mometasone furoate treatment;cold cream
41 Azelaic Acid Versus Hydroquinone in Melasma Unknown status NCT00927771 Phase 4 azelaic acid gel;hydroquinone cream
42 Trial Comparing Calmoseptine Ointment and Desitin Diaper Rash Paste in Diaper Dermatitis in Neonates and Infants Unknown status NCT02716415 Phase 4 Calmoseptine Ointment;Destin Maximum Strength 40% Zinc
43 Imiquimod 3.75% Cream in Combination With Cryotherapy in the Treatment of Hypertrophic Actinic Keratoses Unknown status NCT01229319 Phase 4 Cryotherapy alone to Left arm plus cryotherapy + imiquimod to Right arm;Cryotherapy alone to Left arm plus cryotherapy + imiquimod to Right arm
44 Sienna+® Injection Time Study 4 Arms Unknown status NCT02612870 Phase 4
45 Wound Infections in Breast Cancer Surgery After Preoperative Skin Preparation With Chlorhexidine vs. Povidone-iodine Unknown status NCT02479347 Phase 4 Chlorhexidine;Povidone-Iodine
46 Paclitaxel in Combination With Carboplatin Versus Paclitaxel Plus Epirubicin in Metastatic Breast Cancer Unknown status NCT02207361 Phase 4 Paclitaxel, Carboplatin;Paclitaxel, Epirubicin
47 Weekly and Every 3 Week Administration of Paclitaxel Liposome Injection in Metastatic Breast Cancer Unknown status NCT02142790 Phase 4 paclitaxel liposome injection
48 Safety and Efficacy of Clobetasol Propionate 0.05% E Foam in Alopecia Unknown status NCT01111981 Phase 4 Clobetasol Propionate 0.05% Emollient Foam
49 Proton MR Spectroscopy and 18F-Fluorocholine PET for Breast Cancer Diagnosis Unknown status NCT01956409 Phase 4 18F-FCH;Magnevist
50 Evaluation of Predictive Factors Regarding the Effectivity of Aromatase Inhibitor Therapy (PreFace) Unknown status NCT01908556 Phase 4 Letrozole

Search NIH Clinical Center for Skin Disease

Inferred drug relations via UMLS 69 / NDF-RT 47 :


Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Skin Disease cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Skin Disease:
JACE
Embryonic/Adult Cultured Cells Related to Skin Disease:
Cultured epidermis (JACE PMIDs: 23265935 17465819 11987545

Cochrane evidence based reviews: skin diseases

Genetic Tests for Skin Disease

Genetic tests related to Skin Disease:

# Genetic test Affiliating Genes
1 Abnormality of the Skin 28

Anatomical Context for Skin Disease

The Foundational Model of Anatomy Ontology organs/tissues related to Skin Disease:

18
Skin

MalaCards organs/tissues related to Skin Disease:

38
Skin, Breast, Testes, Lymph Node, Bone, T Cells, Brain

Publications for Skin Disease

Articles related to Skin Disease:

(show top 50) (show all 859)
# Title Authors Year
1
Identification and characterization of lumpy skin disease virus isolated from cattle in the Republic of North Ossetia-Alania in 2015. ( 29363284 )
2018
2
Miscellaneous skin disease and the metabolic syndrome. ( 29241760 )
2018
3
Neuromodulation in Inflammatory Skin Disease. ( 29427206 )
2018
4
Pustular psoriasis and related pustular skin diseases. ( 29333670 )
2018
5
Wild primates threaten efforts to wipe out skin disease. ( 29446404 )
2018
6
Gaps in Workplace Education For Prevention of Occupational Skin Disease. ( 29220520 )
2018
7
Epidemiology of tattoo skin disease in captive common bottlenose dolphins (Tursiops truncatus): Are males more vulnerable than females? ( 29353509 )
2018
8
Skin and Diet: An Update on the Role of Dietary Change as a Treatment Strategy for Skin Disease. ( 29357214 )
2018
9
Cytokine Targeted Therapeutics forA Alopecia Areata: Lessons fromA Atopic Dermatitis and OtherA Inflammatory Skin Diseases. ( 29273110 )
2018
10
Lumpy skin disease outbreaks in Greece during 2015-16, implementation of emergency immunization and genetic differentiation between field isolates and vaccine virus strains. ( 28284627 )
2017
11
Vitiligo: Not Simply a Skin Disease. ( 28528606 )
2017
12
Economic impact of lumpy skin disease and cost effectiveness of vaccination for the control of outbreaks in Ethiopia. ( 29254706 )
2017
13
Long-term changes in the spatial distribution of lumpy skin disease hotspots in Zimbabwe. ( 27785763 )
2017
14
Undifferentiated pleomorphic sarcoma of the skin - a UV-induced occupational skin disease? ( 28220622 )
2017
15
Retinoid Expression in Onchocercal Skin Disease: Pilot Study. ( 29317828 )
2017
16
The genetic basis for most patients with pustular skin disease remains elusive. ( 28887889 )
2017
17
Association Between Inflammatory Skin Disease and Cardiovascular and Cerebrovascular Co-Morbidities in US Adults: Analysis of Nationwide Inpatient Sample Data. ( 28534318 )
2017
18
Two Cases of Successful Treatment of Refractory Chronic Inflammatory Skin Disease, Atopic Dermatitis and Psoriasis with Oral Alitretinoin. ( 28761307 )
2017
19
Global Burden of Skin Disease: Inequities and Innovations. ( 29226027 )
2017
20
Atopic Dermatitis, The Skin-Disease. ( 28905494 )
2017
21
Association between schizophrenia and an autoimmune bullous skin disease-pemphigus: a population-based large-scale study. ( 28942756 )
2017
22
Eosinophils mediate tissue injury in autoimmune skin disease bullous pemphigoid. ( 29246800 )
2017
23
The Molecular Revolution in Cutaneous Biology: Identification of Skin Disease Genes. ( 28411848 )
2017
24
Skin Disease as Art. ( 28492841 )
2017
25
Laser treatment of medical skin disease in women. ( 28831422 )
2017
26
Identification of unique proteomic signatures in allergic and non-allergic skin disease. ( 28703865 )
2017
27
Ultrasound assessment of skin thickness performed on fingers: a tool for estimating overall severity of skin disease in Systemic Sclerosis patients? ( 28917220 )
2017
28
Pre-control relationship of onchocercal skin disease with onchocercal infection in Guinea Savanna, Northern Nigeria. ( 28355223 )
2017
29
Complete Genome Sequence of the Lumpy Skin Disease Virus Isolated from the First Reported Case in Greece in 2015. ( 28729259 )
2017
30
Long-term efficacy and tolerability of mycophenolate mofetil therapy in diffuse scleroderma skin disease. ( 28337853 )
2017
31
Knowledge, attitudes and practices towards yaws and yaws-like skin disease in Ghana. ( 28759580 )
2017
32
Skin disease in captive bats: results of an online survey of zoos and rehabilitators in Europe, North America and Australasia. ( 28044386 )
2017
33
Minimal improvements in the global burden of skin disease from 1990 to 2013. ( 27986134 )
2017
34
RIG-I antiviral signaling drives interleukin-23 production and psoriasis-like skin disease. ( 28377495 )
2017
35
Transmission dynamics of lumpy skin disease in Ethiopia. ( 28768560 )
2017
36
Preventing Occupational Skin Disease: A Review of Training Programs. ( 28509714 )
2017
37
Translation and Validation of the Serbian Version of the Skindex-29 Instrument for Measuring Impact of Skin Disease on Quality of Life. ( 28871926 )
2017
38
Field study on the use of vaccination to control the occurrence of lumpy skin disease in Ethiopian cattle. ( 29254724 )
2017
39
Complete Genome Sequence of Lumpy Skin Disease Virus Isolate SERBIA/Bujanovac/2016, Detected during an Outbreak in the Balkan Area. ( 28860246 )
2017
40
Validation of an Egyptian Arabic Version of Skindex-16 and Quality of Life Measurement in Egyptian Patients with Skin Disease. ( 28748378 )
2017
41
Bacterial diversity in Buruli ulcer skin lesions: Challenges in the clinical microbiome analysis of a skin disease. ( 28750103 )
2017
42
Effective Collaboration on Skin Disease Starts With Medical Education. ( 28350601 )
2017
43
Lumpy skin disease in cattle: Frequency of occurrence in a dairy farm and a preliminary assessment of its possible impact on Egyptian buffaloes. ( 28397517 )
2017
44
Prediction and benefits of minimal disease activity in patients with psoriatic arthritis and active skin disease in the ADEPT trial. ( 29225916 )
2017
45
SCIENTIFIC ABSTRACTS; Skin Disease Education Foundation's 18th Annual Las Vegas Dermatology Seminara8c. ( 29292805 )
2017
46
PAMs ameliorates the imiquimod-induced psoriasis-like skin disease in mice by inhibition of translocation of NF-I_B and production of inflammatory cytokines. ( 28464025 )
2017
47
Anti-inflammatory, tissue remodeling, immunomodulatory, and anticancer activities of oregano (<i>Origanum vulgare</i>) essential oil in a human skin disease model. ( 29450144 )
2017
48
Highlights of Skin Disease Education Foundation's 41st Annual Hawaii Dermatology Seminara8c. ( 28745729 )
2017
49
Development and validation of a TaqMan probe-based real-time PCR method for the differentiation of wild type lumpy skin disease virus from vaccine virus strains. ( 28837841 )
2017
50
Skin biopsy in the diagnosis of inflammatory skin disease. ( 28472573 )
2017

Variations for Skin Disease

Expression for Skin Disease

Search GEO for disease gene expression data for Skin Disease.

Pathways for Skin Disease

Pathways related to Skin Disease according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.95 CDSN DSG1 DSG3 FLG IVL KRT1
2
Show member pathways
11.82 CDSN DSG1 DSG3 FLG IVL KRT1
3
Show member pathways
11.53 DST KRT1 KRT14
4 11.3 IVL KRT1 KRT14
5 10.56 COL17A1 COL7A1 IL4 LAMC2 TNF

GO Terms for Skin Disease

Cellular components related to Skin Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell junction GO:0030054 9.93 COL17A1 DSG1 DSG3 DST GJB3 GJB4
2 cell-cell junction GO:0005911 9.67 CDSN COL17A1 DSG1 GJB3
3 basement membrane GO:0005604 9.46 COL17A1 COL7A1 DST LAMC2
4 desmosome GO:0030057 9.43 CDSN DSG1 DSG3
5 hemidesmosome GO:0030056 9.4 COL17A1 DST
6 intermediate filament GO:0005882 9.35 DST FLG KRT1 KRT10 KRT14
7 epidermal lamellar body GO:0097209 9.32 ABCA12 SPINK5
8 cornified envelope GO:0001533 9.28 CDSN DSG1 DSG3 FLG IVL KRT1
9 extracellular exosome GO:0070062 10.13 CDSN DSG1 DSG3 DST IVL KRT1

Biological processes related to Skin Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell adhesion GO:0007155 9.91 CDSN COL7A1 DSG1 DSG3 DST LAMC2
2 extracellular matrix organization GO:0030198 9.76 COL7A1 LAMC2 SPINK5 TNF
3 peptide cross-linking GO:0018149 9.73 FLG IVL KRT1 KRT10 LOR TGM1
4 epidermis development GO:0008544 9.72 CDSN COL17A1 COL7A1 KRT14 LAMC2
5 keratinocyte differentiation GO:0030216 9.7 ABCA12 CDSN FLG IVL KRT10 LOR
6 keratinization GO:0031424 9.61 ABCA12 DSG1 DSG3 IVL KRT1 KRT10
7 establishment of skin barrier GO:0061436 9.58 ABCA12 FLG KRT1
8 hemidesmosome assembly GO:0031581 9.54 COL17A1 KRT14 LAMC2
9 positive regulation of protein localization to cell surface GO:2000010 9.48 ABCA12 TNF
10 cornification GO:0070268 9.36 CDSN DSG1 DSG3 FLG IVL KRT1

Molecular functions related to Skin Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural molecule activity GO:0005198 9.35 FLG IVL KRT1 KRT10 LOR
2 structural constituent of epidermis GO:0030280 8.92 FLG KRT1 KRT10 LOR

Sources for Skin Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
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47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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