MCID: SKN020
MIFTS: 34

Skin Papilloma

Categories: Skin diseases, Cancer diseases

Aliases & Classifications for Skin Papilloma

MalaCards integrated aliases for Skin Papilloma:

Name: Skin Papilloma 12 14 69
Cutaneous Papilloma 12
Skin Papilloma Nos 12
Papilloma of Skin 12
Papilloma Skin 51

Classifications:



External Ids:

Disease Ontology 12 DOID:3178
NCIt 46 C4614
UMLS 69 C0347390

Summaries for Skin Papilloma

MalaCards based summary : Skin Papilloma, also known as cutaneous papilloma, is related to squamous cell papilloma of skin and papilloma. An important gene associated with Skin Papilloma is SP8 (Sp8 Transcription Factor), and among its related pathways/superpathways is Influenza A. The drugs Miconazole and Salicylic acid have been mentioned in the context of this disorder. Affiliated tissues include skin, testes and kidney, and related phenotypes are cellular and growth/size/body region

Related Diseases for Skin Papilloma

Diseases related to Skin Papilloma via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 squamous cell papilloma of skin 11.0
2 papilloma 10.4
3 adenoma 9.8
4 multiple mitochondrial dysfunctions syndrome 5 9.6
5 breast adenoma 9.6
6 lung adenoma 9.6
7 endotheliitis 9.6

Graphical network of the top 20 diseases related to Skin Papilloma:



Diseases related to Skin Papilloma

Symptoms & Phenotypes for Skin Papilloma

MGI Mouse Phenotypes related to Skin Papilloma:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.7 SP8 CCDC39 EIF2AK4 IRF9 MAP2K2 ODC1
2 growth/size/body region MP:0005378 9.43 SP8 CCDC39 EIF2AK4 MAP2K2 ODC1 SMARCAL1
3 skeleton MP:0005390 9.02 SP8 CCDC39 IRF9 MAP2K2 SMARCAL1

Drugs & Therapeutics for Skin Papilloma

Drugs for Skin Papilloma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 133)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3 22916-47-8 4189
2
Salicylic acid Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3 69-72-7 338
3
Imiquimod Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 99011-02-6 57469
4
Zinc Approved, Investigational Phase 4,Phase 2,Phase 3 7440-66-6 32051 23994
5
Fluorouracil Approved Phase 4 51-21-8 3385
6 Analgesics Phase 4,Phase 2,Phase 3
7 Analgesics, Non-Narcotic Phase 4,Phase 2,Phase 3
8 Antifungal Agents Phase 4,Phase 2,Phase 3
9 Anti-Infective Agents Phase 4,Phase 2,Phase 3,Phase 1
10 Anti-Inflammatory Agents Phase 4,Phase 2,Phase 3
11 Anti-Inflammatory Agents, Non-Steroidal Phase 4,Phase 2,Phase 3
12 Antirheumatic Agents Phase 4,Phase 2,Phase 3
13 Cyclooxygenase Inhibitors Phase 4,Phase 2,Phase 3
14 Dermatologic Agents Phase 4,Phase 2,Phase 3
15 Keratolytic Agents Phase 4,Phase 2,Phase 3
16 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 3
17 Salicylates Phase 4,Phase 2,Phase 3
18 Liver Extracts Phase 4,Phase 3
19 Vaccines Phase 4,Phase 3,Phase 2,Phase 1
20 Immunosuppressive Agents Phase 4,Phase 3,Phase 2,Phase 1
21 Adjuvants, Immunologic Phase 4,Phase 3,Phase 2,Phase 1
22 Interferon Inducers Phase 4,Phase 3,Phase 2,Phase 1
23 interferons Phase 4,Phase 3,Phase 2,Phase 1
24 Antibodies Phase 4,Phase 1
25 Immunoglobulins Phase 4,Phase 1
26 Micronutrients Phase 4,Phase 2,Phase 3
27 Trace Elements Phase 4,Phase 2,Phase 3
28 Antimetabolites Phase 4,Phase 1,Phase 2
29 Antimetabolites, Antineoplastic Phase 4,Phase 1,Phase 2
30 pyruvate Nutraceutical Phase 4,Phase 2,Phase 3
31
Catechin Nutraceutical Phase 4,Phase 1 154-23-4 9064
32
Epicatechin Investigational, Nutraceutical Phase 4,Phase 1 490-46-0 72276
33 Tea Nutraceutical Phase 4,Phase 3,Phase 2,Phase 1
34
Ethanol Approved Phase 2, Phase 3 64-17-5 702
35
Petrolatum Approved, Investigational Phase 2, Phase 3 8009-03-8
36
Aminolevulinic acid Approved Phase 3 106-60-5 137
37
Cyclophosphamide Approved, Investigational Phase 3 50-18-0, 6055-19-2 2907
38
Pancrelipase Approved, Investigational Phase 3 53608-75-6
39
Benzocaine Approved, Investigational Phase 3 1994-09-7, 94-09-7 2337
40
Furosemide Approved, Vet_approved Phase 3,Phase 2 54-31-9 3440
41
Lenograstim Approved, Investigational Phase 3 135968-09-1
42 Zinc sulfate Approved, Investigational Phase 3 7733-02-0
43 tannic acid Approved, Nutraceutical Phase 3
44 Pharmaceutical Solutions Phase 2, Phase 3, Phase 1
45 Alkylating Agents Phase 3
46 Methyl 5-aminolevulinate Phase 3
47 Photosensitizing Agents Phase 3
48 pancreatin Phase 3
49 Anti-HIV Agents Phase 3,Phase 1
50 Anti-Retroviral Agents Phase 3,Phase 1

Interventional clinical trials:

(show top 50) (show all 185)

# Name Status NCT ID Phase Drugs
1 17% Salicylate Versus 17% Salicylate-Ethyl Pyruvate for Plantar Foot Warts Unknown status NCT01712295 Phase 4 17% Salicylate with ethyl pyruvate;Salicylates
2 Does the HPV Vaccine Cause the Same Response in Adolescent Kidney and Liver Transplant Patients as in Healthy Controls? Unknown status NCT01101750 Phase 4
3 Imiquimod 5% Cream in the Treatment of External Genital or Perianal Warts in HIV+ Patients Completed NCT00761371 Phase 4 Imiquimod 5% cream
4 Study of Imiquimod Cream Prior to Ablative Therapy in External Ano-Genital Warts Completed NCT00189293 Phase 4 Imiquimod
5 Pharmacokinetic Study of Topically Applied Veregen 15% Compared With Oral Intake of Green Tea Beverage Completed NCT01082302 Phase 4 Polyphenon E (Veregen) 15% ointment
6 Investigating Veregen ™ 15% Ointment Treatment For Non-facial Verrucae in Pediatric Patients: A Pilot Study Completed NCT02622568 Phase 4 Veregen only
7 Pulsed 1064nm Nd:YAG in the Treatment of Verruca Vulgaris Versus Conventional Therapy With Liquid Nitrogen Cryotherapy Completed NCT01609530 Phase 4
8 Alternate Dosing Schedules Study for HPV Vaccine (ADS) Completed NCT02280642 Phase 4
9 Alternate Dosing Schedules Study for HPV Vaccine Completed NCT00862810 Phase 4
10 Intralesional Measles, Mumps, Rubella (MMR) Vaccine Versus Cryotherapy in Treatment of Multiple Common and Planter Warts Recruiting NCT03183765 Phase 4 Measles-Mumps-Rubella Vaccine
11 Scientific Evaluation of One or Two Doses of the Bivalent or Nonavalent Prophylactic HPV Vaccines Recruiting NCT03180034 Phase 4
12 HPV (Human Papilloma Virus) Vaccination After Treatment of Anal Intraepithelial Neoplasia (AIN) Recruiting NCT02087384 Phase 4 Placebo
13 Immunogenicity and Safety of Human Papilloma Virus Vaccine in Solid Organ Transplant Recipients Active, not recruiting NCT02624349 Phase 4 Quadravalent human papillomavirus vaccine
14 A RTC to Examine the Effectiveness of 400 mg of Oral Zinc Gluconate as Adjunctive Therapy for Ano-genital Warts Terminated NCT01468636 Phase 4 Oral Zinc;Placebo
15 Comparison of Five Treatments in Patients With Plantar Warts Terminated NCT01059110 Phase 4 Salicylate ointment;Imiquimod;5-Fluoro-Uracil;Cryotherapy
16 Pyruvic Acid Versus Salicylic Acid Preparation in Treatment of Plantar Warts Unknown status NCT02151630 Phase 2, Phase 3 Pyruvic acid;Salicylic Acid
17 Efficacy of Laser Versus Cryotherapy in the Treatment of Warts Unknown status NCT01808443 Phase 3
18 Topical 5-ALA Photodynamic Therapy for the Treatment of Verruca Vulgaris Unknown status NCT00155584 Phase 3
19 Two-dose Schedule of Quadrivalent HPV Recombinant Vaccine in 11-year-old Boys in Mexico City Unknown status NCT02382900 Phase 3
20 Phase 3 Study of Imiquimod Creams in the Treatment of External Genital Warts Completed NCT00735462 Phase 3 2.5% imiquimod cream;3.75% imiquimod cream;Placebo cream
21 Safety and Effectiveness Study of Imiquimod Creams in the Treatment of External Genital Warts Completed NCT00674739 Phase 3 Imiquimod;3.75% imiquimod cream;placebo cream
22 Oral Zinc Gluconate as Treatment for Recalcitrant Cutaneous Warts: A Randomized, Double-blind, Placebo-controlled Trial Completed NCT01783353 Phase 2, Phase 3
23 Low Dose Cyclophosphamide Treats Genital Warts Completed NCT00999986 Phase 3 cyclophosphamide
24 Glizigen-Viudid-External Anogenital Warts in Children and Adolescents Completed NCT01111344 Phase 3
25 Cervical Intraepithelial Neoplasm (CIN)-Warts Efficacy Trial in Women (Gardasil)(V501-013)(COMPLETED) Completed NCT00092521 Phase 3
26 An Investigational Study of Gardasil™ (qHPV, V501) Vaccine in Reducing the Incidence of Anogenital Warts in Young Men (V501-020) Completed NCT00090285 Phase 3
27 Efficacy and Safety Study of Polyphenon E to Treat External Genital Warts Completed NCT00449982 Phase 3 Polyphenon E Ointment 10%, Polyphenon E Ointment 15%
28 PDT With Metvix® 160 mg/g Cream in Organ Transplant Recipients With Non-melanoma Skin Cancer Completed NCT00472459 Phase 3
29 Study to Test the Safety of HPV Vaccine in Women (V501-011)(COMPLETED) Completed NCT00517309 Phase 3
30 A Controlled Trial to Assess the Immunogenicity of a Proposed Paediatric Dosing Schedule of Human Papillomavirus Vaccine Completed NCT00501137 Phase 3
31 Cervical Intraepithelial Neoplasm (CIN) in Women (Gardasil)(V501-015) Completed NCT00092534 Phase 3
32 Study of an Investigational Vaccine in Pre-Adolescents and Adolescents (Gardasil)(V501-016) Completed NCT00092495 Phase 3
33 Immunogenicity Bridge Between an Investigational Monovalent Vaccine and the Equivalent Component of Gardasil (V501) a Quadrivalent Vaccine (V501-012)(COMPLETED) Completed NCT00092482 Phase 3
34 Evaluation of Long Term Immunity Following HPV Vaccination Completed NCT02276521 Phase 2, Phase 3
35 A Study of V503, a 9-valent Human Papillomavirus (9vHPV) Vaccine in Females 12-26 Years of Age Who Have Previously Received GARDASIL™ (V503-006) Completed NCT01047345 Phase 3
36 Multivalent HPV (Human Papillomavirus) Vaccine Study in 16- to 26-Year Old Men and Women (V503-003) Completed NCT01651949 Phase 3
37 Safety and Immunogenicity of Human Papillomavirus (HPV) Vaccine in Solid Organ Transplant Recipients Completed NCT00677677 Phase 3
38 Protecting Young Special Risk Females From Cervical Cancer Through Human Papilloma Virus (HPV) Vaccination Completed NCT00964210 Phase 3 Licensed quadrivalent HPV vaccine, Gardasil
39 Immunogenicity of GlaxoSmithKline Biological's Human Papillomavirus (HPV) Vaccine (580299) Versus Merck's Gardasil® in Healthy Females 18-45 Years of Age Completed NCT00423046 Phase 3
40 Topical Green Tea Ointment in Treatment of Superficial Skin Cancer Completed NCT02029352 Phase 2, Phase 3 Sinecatechins 10%;Placebo
41 Broad Spectrum HPV (Human Papillomavirus) Vaccine Study in 16-to 26-Year-Old Women (V503-001) Completed NCT00543543 Phase 3
42 A Study to Evaluate the Safety, Immune Response, and Efficacy of Gardasil (V501, qHPV) in Mid-Adult Women (V501-019) Completed NCT00090220 Phase 3
43 GARDASIL™ Study in Healthy Females Between 9 and 26 Years of Age in Sub-Saharan Africa (V501-046) Completed NCT01245764 Phase 3
44 A Study of Gardasil (V501) in Preadolescents and Adolescents (V501-018) Completed NCT00092547 Phase 3
45 Efficacy of Quadrivalent HPV Vaccine to Prevent Relapses of Genital Warts After Initial Therapeutic Response Recruiting NCT03296397 Phase 3
46 A Study to Evaluate the Safety and Efficacy of CLS006 Versus Vehicle in Subjects 2 Years of Age or Older With Cutaneous Common Warts Recruiting NCT03259620 Phase 3 CLS006;CLS006 Vehicle
47 Plerixafor Versus G-CSF in the Treatment of People With WHIM Syndrome Recruiting NCT02231879 Phase 3 Plerixafor;G-CSF
48 A Trial of X4P-001 in Patients With WHIM Syndrome Recruiting NCT03005327 Phase 2, Phase 3 X4P-001;Placebo
49 Radiotherapy or Imiquimod in Complex Lentigo Maligna Recruiting NCT02394132 Phase 3 Imiquimod
50 Immunogenicity and Tolerability of Broad Spectrum Human Papillomavirus (HPV) Vaccine in Adult and Young Adult Women (V503-004) Recruiting NCT03158220 Phase 3

Search NIH Clinical Center for Skin Papilloma

Genetic Tests for Skin Papilloma

Anatomical Context for Skin Papilloma

MalaCards organs/tissues related to Skin Papilloma:

38
Skin, Testes, Kidney, Liver, Bone, Breast, Endothelial

Publications for Skin Papilloma

Articles related to Skin Papilloma:

(show all 40)
# Title Authors Year
1
Poly-MVA attenuates 7,12- dimethylbenz[a]anthracene initiated and croton oil promoted skin papilloma formation on mice skin. ( 28976135 )
2017
2
Deletion of epidermal Rac1 inhibits HPV-8 induced skin papilloma formation and facilitates HPV-8- and UV-light induced skin carcinogenesis. ( 27506937 )
2016
3
Attenuation of DMBA/croton oil induced mouse skin papilloma by Apodytes dimidiata mediated by its antioxidant and antimutagenic potential. ( 26878464 )
2016
4
Activation of MEK2 is sufficient to induce skin papilloma formation in transgenic zebrafish. ( 26572230 )
2015
5
The loss of Tm7sf gene accelerates skin papilloma formation in mice. ( 25804527 )
2015
6
Flower-deficient mice have reduced susceptibility to skin papilloma formation. ( 22362363 )
2012
7
Photodynamic therapy using a novel photosensitizer, TONS501, is similarly effective to ALA and EC036 photodynamic therapy on DMBA-and TPA-induced mouse skin papilloma. ( 22464765 )
2012
8
Phellinus rimosus (Berk.) pilat attenuates 7,12-dimethylbenz[a] anthracene induced and croton oil promoted skin papilloma formation in mice. ( 22070052 )
2011
9
Bilharzia of the breast masquerading as a breast skin papilloma in a pregnant woman. ( 22353277 )
2011
10
Increased skin papilloma formation in mice lacking glutathione transferase GSTP. ( 21975931 )
2011
11
Modulation of Signal Proteins: A Plausible Mechanism to Explain How a Potentized Drug Secale Cor 30C Diluted beyond Avogadro's Limit Combats Skin Papilloma in Mice. ( 19617203 )
2011
12
Mouse Prkar1a haploinsufficiency leads to an increase in tumors in the Trp53+/- or Rb1+/- backgrounds and chemically induced skin papillomas by dysregulation of the cell cycle and Wnt signaling. ( 20080939 )
2010
13
Anti-oncogenic potentials of a plant coumarin (7-hydroxy-6-methoxy coumarin) against 7,12-dimethylbenz [a] anthracene-induced skin papilloma in mice: the possible role of several key signal proteins. ( 20619141 )
2010
14
The prostaglandin receptor EP2 activates multiple signaling pathways and beta-arrestin1 complex formation during mouse skin papilloma development. ( 19587094 )
2009
15
Potential of diallyl sulfide bearing pH-sensitive liposomes in chemoprevention against DMBA-induced skin papilloma. ( 17622315 )
2007
16
Reduction in IkappaB kinase alpha expression promotes the development of skin papillomas and carcinomas. ( 17909021 )
2007
17
Congenital mucus retention cyst of penis presenting as skin papilloma. ( 17320684 )
2007
18
Identification of genes and gene ontology processes critical to skin papilloma development in Tg.AC transgenic mice. ( 16329151 )
2006
19
Mutation of p53 in skin papilloma and tubular breast adenoma of albino mice. ( 16624193 )
2006
20
Treatment of skin papillomas with topical alpha-lactalbumin-oleic acid. ( 15215482 )
2004
21
Control of intracellular movement of connexins by E-cadherin in murine skin papilloma cells. ( 11640887 )
2001
22
Prevention of carcinogen-induced mouse skin papilloma by whole fruit aqueous extract of Momordica charantia. ( 10958332 )
2000
23
Topical retinoic acid reduces skin papilloma formation but resistant papillomas are at high risk for malignant conversion. ( 9537245 )
1998
24
Comparative expression of novel vascular endothelial growth factor/vascular permeability factor transcripts in skin, papillomas, and carcinomas of v-Ha-ras Tg.AC transgenic mice and FVB/N mice. ( 9647747 )
1998
25
Mathematical modeling of skin papilloma data in SENCAR mice. ( 9439737 )
1997
26
Suppression of mouse skin papilloma by canthaxanthin and beta-carotene in vivo: possibility of the regression of tumorigenesis by carotenoids without conversion to retinoic acid. ( 8875557 )
1996
27
Inhibition of 12-O-tetradecanoylphorbol-13-acetate promoted mouse skin papilloma by digalactosyl diacylglycerols from the fresh water cyanobacterium Phormidium tenue. ( 8640752 )
1996
28
Expression of protein kinase C isoforms in skin papilloma and carcinoma of mice. ( 8062222 )
1994
29
Effect of excess dietary retinoic acid on skin papilloma and carcinoma formation induced by a complete carcinogenesis protocol in female Sencar mice. ( 8180970 )
1994
30
Mouse skin papilloma formation by chronic dermal application of 7,12-dimethylbenz[a]anthracene is not reduced by diet restriction. ( 8293538 )
1994
31
Effects of dietary retinoic acid on skin papilloma and carcinoma formation in female SENCAR mice. ( 8453733 )
1993
32
Dietary retinoids are essential for skin papilloma formation induced by either the two-stage or the complete tumorigenesis model in female SENCAR mice. ( 1451104 )
1992
33
Inhibition of 12-O-tetradecanoylphorbol-13-acetate-promoted mouse skin papilloma by saponins. ( 1846234 )
1991
34
Inhibition of 7,12-dimethylbenz[a]anthracene-initiated and 12-O-tetradecanoylphorbol-13-acetate-promoted skin papilloma formation in mice by dehydroepiandrosterone and two synthetic analogs. ( 2529051 )
1989
35
A combined carcinogen bioassay utilizing both the lung adenoma and skin papilloma protocols. ( 3780626 )
1986
36
Inhibition by quercetin of the promoting effect of teleocidin on skin papilloma formation in mice initiated with 7,12-dimethylbenz[a]anthracene. ( 6428958 )
1984
37
Dehydroepiandrosterone (DHEA) and 3 beta-methylandrost-5-en-17-one: inhibitors of 7,12-dimethylbenz[a]anthracene (DMBA)-initiated and 12-O-tetradecanoylphorbol-13-acetate (TPA)-promoted skin papilloma formation in mice. ( 6231135 )
1984
38
Further studies of eel virus (Berlin) isolated from the blood of eels (Anguilla anguilla) with skin papilloma. ( 981684 )
1976
39
Suspicious influence of thymectomy on skin papilloma induction. ( 5781976 )
1969
40
Close-packed array of virus-like particles within cells of a human skin papilloma. ( 13121031 )
1953

Variations for Skin Papilloma

Expression for Skin Papilloma

Search GEO for disease gene expression data for Skin Papilloma.

Pathways for Skin Papilloma

Pathways related to Skin Papilloma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.49 EIF2AK4 IRF9 MAP2K2

GO Terms for Skin Papilloma

Sources for Skin Papilloma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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