MCID: SKN020
MIFTS: 39

Skin Papilloma malady

Skin diseases category

Summaries for Skin Papilloma

About this section
Sources:
32MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
MalaCards: Skin Papilloma, also known as cutaneous papilloma, is related to papilloma and adenoma. An important gene associated with Skin Papilloma is SP8 (Sp8 transcription factor), and among its related pathways are Integrated Breast Cancer Pathway and Integrated Pancreatic Cancer Pathway. The compounds 3,3-diindolylmethane and temozolomide have been mentioned in the context of this disorder. Affiliated tissues include skin, breast and lung, and related mouse phenotypes are digestive/alimentary and craniofacial.

Aliases & Classifications for Skin Papilloma

About this section
Sources:
8Disease Ontology, 10DISEASES, 60UMLS, 44Novoseek, 39NCIt, 56SNOMED-CT
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Skin diseases


Aliases & Descriptions:

skin papilloma 8 10 60
cutaneous papilloma 8
skin papilloma nos 8
papilloma of skin 8
papilloma skin 44


External Ids:

Disease Ontology8 DOID:3178
NCIt39 C4614

Related Diseases for Skin Papilloma

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Graphical network of the top 20 diseases related to Skin Papilloma:



Diseases related to skin papilloma

Clinical Features for Skin Papilloma

About this section

Drugs & Therapeutics for Skin Papilloma

About this section
Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Skin Papilloma

Drug clinical trials:

Search ClinicalTrials for Skin Papilloma

Search NIH Clinical Center for Skin Papilloma

Search CenterWatch for Skin Papilloma

Genetic Tests for Skin Papilloma

About this section

Anatomical Context for Skin Papilloma

About this section
Sources:
32MalaCards
See all sources

MalaCards organs/tissues related to Skin Papilloma:

32
Skin, Breast, Lung, Endothelial

Animal Models for Skin Papilloma or affiliated genes

About this section
Sources:
36MGI
See all sources

MGI Mouse Phenotypes related to Skin Papilloma:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053818.8TP53, SP8, PRKAR1A, CHUK, VEGFA
2MP:00053828.7TP53, VEGFA, PRKAR1A, CHUK, SP8
3MP:00053888.5CHUK, VEGFA, SP8, TP53, PRKAR1A
4MP:00053908.4TP53, PRKAR1A, CHUK, VEGFA, SP8, SMARCAL1

Publications for Skin Papilloma

About this section
Sources:
50PubMed
See all sources

Articles related to Skin Papilloma:

(show all 45)
idTitleAuthorsYear
1
IL-13 but not IL-4 signaling via IL-4RI+ protects mice from papilloma formation during DMBA/TPA two-step skin carcinogenesis. (24403255)
2013
2
Flower-deficient mice have reduced susceptibility to skin papilloma formation. (22362363)
2012
3
Photodynamic therapy using a novel photosensitizer, TONS501, is similarly effective to ALA and EC036 photodynamic therapy on DMBA-and TPA-induced mouse skin papilloma. (22464765)
2012
4
Esophageal papillomas and skin abnormalities. Focal dermal hypoplasia (Goltz syndrome) manifesting with esophageal papillomatosis. (21272558)
2011
5
Modulation of Signal Proteins: A Plausible Mechanism to Explain How a Potentized Drug Secale Cor 30C Diluted beyond Avogadro's Limit Combats Skin Papilloma in Mice. (19617203)
2011
6
Increased skin papilloma formation in mice lacking glutathione transferase GSTP. (21975931)
2011
7
Dendritic cell subsets and immunological milieu in inflammatory human papilloma virus-related skin lesions. (21715145)
2011
8
Phellinus rimosus (Berk.) pilat attenuates 7,12-dimethylbenz[a] anthracene induced and croton oil promoted skin papilloma formation in mice. (22070052)
2011
9
Detection of human papilloma virus in normal skin and in superficial and nodular basal cell carcinomas in immunocompetent subjects. (21054564)
2011
10
Bilharzia of the breast masquerading as a breast skin papilloma in a pregnant woman. (22353277)
2011
11
Anti-oncogenic potentials of a plant coumarin (7-hydroxy-6-methoxy coumarin) against 7,12-dimethylbenz [a] anthracene-induced skin papilloma in mice: the possible role of several key signal proteins. (20619141)
2010
12
Mouse Prkar1a haploinsufficiency leads to an increase in tumors in the Trp53+/- or Rb1+/- backgrounds and chemically induced skin papillomas by dysregulation of the cell cycle and Wnt signaling. (20080939)
2010
13
The prostaglandin receptor EP2 activates multiple signaling pathways and beta-arrestin1 complex formation during mouse skin papilloma development. (19587094)
2009
14
Potential of diallyl sulfide bearing pH-sensitive liposomes in chemoprevention against DMBA-induced skin papilloma. (17622315)
2007
15
A case of neglected inverted papilloma with invasion to the skin. (17536095)
2007
16
Congenital mucus retention cyst of penis presenting as skin papilloma. (17320684)
2007
17
Reduction in IkappaB kinase alpha expression promotes the development of skin papillomas and carcinomas. (17909021)
2007
18
Mutation of p53 in skin papilloma and tubular breast adenoma of albino mice. (16624193)
2006
19
Detection of mucosal human papilloma virus DNA in bowenoid papulosis, Bowen's disease and squamous cell carcinoma of the skin. (16700665)
2006
20
Identification of genes and gene ontology processes critical to skin papilloma development in Tg.AC transgenic mice. (16329151)
2006
21
Treatment of skin papillomas with topical alpha-lactalbumin-oleic acid. (15215482)
2004
22
Survivin expression in mouse skin prevents papilloma regression and promotes chemical-induced tumor progression. (12566297)
2003
23
Control of intracellular movement of connexins by E-cadherin in murine skin papilloma cells. (11640887)
2001
24
Prevention of carcinogen-induced mouse skin papilloma by whole fruit aqueous extract of Momordica charantia. (10958332)
2000
25
Comparative expression of novel vascular endothelial growth factor/vascular permeability factor transcripts in skin, papillomas, and carcinomas of v-Ha-ras Tg.AC transgenic mice and FVB/N mice. (9647747)
1998
26
Topical retinoic acid reduces skin papilloma formation but resistant papillomas are at high risk for malignant conversion. (9537245)
1998
27
Mathematical modeling of skin papilloma data in SENCAR mice. (9439737)
1997
28
Suppression of mouse skin papilloma by canthaxanthin and beta-carotene in vivo: possibility of the regression of tumorigenesis by carotenoids without conversion to retinoic acid. (8875557)
1996
29
Inhibition of 12-O-tetradecanoylphorbol-13-acetate promoted mouse skin papilloma by digalactosyl diacylglycerols from the fresh water cyanobacterium Phormidium tenue. (8640752)
1996
30
Effect of excess dietary retinoic acid on skin papilloma and carcinoma formation induced by a complete carcinogenesis protocol in female Sencar mice. (8180970)
1994
31
Multiple metachronous skin squamous cell carcinomas and epidermodysplasia verruciformis in the head region: a human papilloma virus-associated disease. (7848644)
1994
32
Expression of protein kinase C isoforms in skin papilloma and carcinoma of mice. (8062222)
1994
33
Mouse skin papilloma formation by chronic dermal application of 7,12-dimethylbenz[a]anthracene is not reduced by diet restriction. (8293538)
1994
34
Effects of dietary retinoic acid on skin papilloma and carcinoma formation in female SENCAR mice. (8453733)
1993
35
Enhanced papilloma formation in response to skin tumor promotion in transgenic mice overexpressing the human ornithine decarboxylase gene. (1520339)
1992
36
Dietary retinoids are essential for skin papilloma formation induced by either the two-stage or the complete tumorigenesis model in female SENCAR mice. (1451104)
1992
37
Inhibition of 12-O-tetradecanoylphorbol-13-acetate-promoted mouse skin papilloma by saponins. (1846234)
1991
38
Skin hyperkeratosis and papilloma formation in transgenic mice expressing a ras oncogene from a suprabasal keratin promoter. (1696852)
1990
39
Inhibition of 7,12-dimethylbenz[a]anthracene-initiated and 12-O-tetradecanoylphorbol-13-acetate-promoted skin papilloma formation in mice by dehydroepiandrosterone and two synthetic analogs. (2529051)
1989
40
A combined carcinogen bioassay utilizing both the lung adenoma and skin papilloma protocols. (3780626)
1986
41
Dehydroepiandrosterone (DHEA) and 3 beta-methylandrost-5-en-17-one: inhibitors of 7,12-dimethylbenz[a]anthracene (DMBA)-initiated and 12-O-tetradecanoylphorbol-13-acetate (TPA)-promoted skin papilloma formation in mice. (6231135)
1984
42
Inhibition by quercetin of the promoting effect of teleocidin on skin papilloma formation in mice initiated with 7,12-dimethylbenz[a]anthracene. (6428958)
1984
43
Further studies of eel virus (Berlin) isolated from the blood of eels (Anguilla anguilla) with skin papilloma. (981684)
1976
44
Suspicious influence of thymectomy on skin papilloma induction. (5781976)
1969
45
Close-packed array of virus-like particles within cells of a human skin papilloma. (13121031)
1953

Genetic Variations for Skin Papilloma

About this section

Expression for genes affiliated with Skin Papilloma

About this section
Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Skin Papilloma

Search GEO for disease gene expression data for Skin Papilloma.

Pathways for genes affiliated with Skin Papilloma

About this section
Sources:
37NCBI BioSystems Database, 29KEGG, 51QIAGEN
See all sources

Compounds for genes affiliated with Skin Papilloma

About this section
Sources:
44Novoseek, 11DrugBank, 49PharmGKB, 59Tocris Bioscience, 24HMDB
See all sources

Compounds related to Skin Papilloma according to GeneCards/GeneDecks:

(show all 12)
idCompoundScoreTop Affiliating Genes
13,3-diindolylmethane449.9TP53, VEGFA
2temozolomide44 1110.8TP53, VEGFA
3taxane449.8VEGFA, TP53
4triptolide449.8TP53, VEGFA
5bortezomib44 1110.7TP53, VEGFA, CHUK
6geldanamycin44 49 59 1112.7TP53, VEGFA, CHUK
7resveratrol44 59 11 2412.7CHUK, VEGFA, TP53
8egcg449.7TP53, VEGFA, CHUK
9curcumin449.6CHUK, VEGFA, TP53
10arsenite44 2410.6TP53, VEGFA, CHUK
11radicicol44 59 1111.5TP53, VEGFA
125fluorouracil449.4TP53, VEGFA, CHUK

GO Terms for genes affiliated with Skin Papilloma

About this section
Sources:
16Gene Ontology
See all sources

Biological processes related to Skin Papilloma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1lactationGO:0075959.8VEGFA, CHUK
2DNA strand renaturationGO:0007339.8TP53, SMARCAL1
3mammary gland alveolus developmentGO:0607499.7VEGFA, CHUK
4regulation of transcription from RNA polymerase II promoterGO:0063579.1SMARCAL1, VEGFA, PRKAR1A

Products for genes affiliated with Skin Papilloma

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Skin Papilloma

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet