MCID: SKN020
MIFTS: 34

Skin Papilloma malady

Summaries for Skin Papilloma

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33MalaCards
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MalaCards: Skin Papilloma, also known as cutaneous papilloma, is related to adenoma and squamous cell papilloma. An important gene associated with Skin Papilloma is SP8 (Sp8 transcription factor), and among its related pathways are Integrated Breast Cancer Pathway and Integrated Pancreatic Cancer Pathway. The compounds 3,3-diindolylmethane and temozolomide have been mentioned in the context of this disorder. Related mouse phenotypes are digestive/alimentary and craniofacial.

Aliases & Classifications for Skin Papilloma

Sources:
8Disease Ontology, 10DISEASES, 61UMLS, 45Novoseek, 40NCIt, 57SNOMED-CT
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Aliases & Descriptions:

skin papilloma 8 10 61
cutaneous papilloma 8
skin papilloma nos 8
papilloma of skin 8
papilloma skin 45


External Ids:

Disease Ontology8 DOID:3178
NCIt40 C4614

Related Diseases for Skin Papilloma

Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Skin Papilloma:



Diseases related to skin papilloma

Clinical Features for Skin Papilloma

Drugs & Therapeutics for Skin Papilloma

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
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Approved drugs:

Search CenterWatch for Skin Papilloma

Drug clinical trials:

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Search NIH Clinical Center for Skin Papilloma

Search CenterWatch for Skin Papilloma

Genetic Tests for Skin Papilloma

Anatomical Context for Skin Papilloma

Animal Models for Skin Papilloma or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
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MGI Mouse Phenotypes related to Skin Papilloma:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053818.8TP53, SP8, PRKAR1A, CHUK, VEGFA
2MP:00053828.7TP53, VEGFA, PRKAR1A, CHUK, SP8
3MP:00053888.5CHUK, VEGFA, SP8, TP53, PRKAR1A
4MP:00053908.4TP53, PRKAR1A, CHUK, VEGFA, SP8, SMARCAL1

Publications for Skin Papilloma

Sources:
51PubMed
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Articles related to Skin Papilloma:

(show top 50)    (show all 95)
idTitleAuthorsYear
1
Case-control study of cutaneous human papillomavirus infection in Basal cell carcinoma of the skin. (23303448)
2013
2
IL-13 but not IL-4 signaling via IL-4RI+ protects mice from papilloma formation during DMBA/TPA two-step skin carcinogenesis. (24403255)
2013
3
Cutaneous human papillomavirus infection and Basal cell carcinoma of the skin. (23673499)
2013
4
Detection of Human Papillomavirus in Nonmelanoma Skin Cancer Lesions and Healthy Perilesional Skin in Kidney Transplant Recipients and Immunocompetent Patients. (24360728)
2013
5
Human papillomavirus and squamous cell cancer of the skin--epidermodysplasia verruciformis-associated human papillomavirus revisited. (22377919)
2012
6
Photodynamic therapy using a novel photosensitizer, TONS501, is similarly effective to ALA and EC036 photodynamic therapy on DMBA-and TPA-induced mouse skin papilloma. (22464765)
2012
7
Esophageal papillomas and skin abnormalities. Focal dermal hypoplasia (Goltz syndrome) manifesting with esophageal papillomatosis. (21272558)
2011
8
Modulation of Signal Proteins: A Plausible Mechanism to Explain How a Potentized Drug Secale Cor 30C Diluted beyond Avogadro's Limit Combats Skin Papilloma in Mice. (19617203)
2011
9
Dendritic cell subsets and immunological milieu in inflammatory human papilloma virus-related skin lesions. (21715145)
2011
10
Phellinus rimosus (Berk.) pilat attenuates 7,12-dimethylbenz[a] anthracene induced and croton oil promoted skin papilloma formation in mice. (22070052)
2011
11
Bilharzia of the breast masquerading as a breast skin papilloma in a pregnant woman. (22353277)
2011
12
A case of epidermodysplasia verruciformis (EV) with human papillomavirus 16 (HPV16) DNA detected in the skin lesions: can HPV16 infect patients with EV? (22126886)
2011
13
The E2 protein of human papillomavirus type 8 increases the expression of matrix metalloproteinase-9 in human keratinocytes and organotypic skin cultures. (21274725)
2011
14
HLA-DR alleles associated with skin warts induced by human papillomavirus infection. (21155086)
2010
15
Mouse Prkar1a haploinsufficiency leads to an increase in tumors in the Trp53+/- or Rb1+/- backgrounds and chemically induced skin papillomas by dysregulation of the cell cycle and Wnt signaling. (20080939)
2010
16
The prostaglandin receptor EP2 activates multiple signaling pathways and beta-arrestin1 complex formation during mouse skin papilloma development. (19587094)
2009
17
Reduction in IkappaB kinase alpha expression promotes the development of skin papillomas and carcinomas. (17909021)
2007
18
The characteristics of human papillomavirus expression and cell proliferation in actinic keratosis and Bowen's disease of the skin. (16905862)
2006
19
Detection of mucosal human papilloma virus DNA in bowenoid papulosis, Bowen's disease and squamous cell carcinoma of the skin. (16700665)
2006
20
Identification of genes and gene ontology processes critical to skin papilloma development in Tg.AC transgenic mice. (16329151)
2006
21
Human papillomaviruses associated with epidermodysplasia verruciformis in non-melanoma skin cancers: guilty or innocent? (15982294)
2005
22
The E7 protein of cutaneous human papillomavirus type 8 causes invasion of human keratinocytes into the dermis in organotypic cultures of skin. (15781634)
2005
23
Treatment of skin papillomas with topical alpha-lactalbumin-oleic acid. (15215482)
2004
24
Survivin expression in mouse skin prevents papilloma regression and promotes chemical-induced tumor progression. (12566297)
2003
25
Depletion of Langerhans cells in human papillomavirus type 16-infected skin is associated with E6-mediated down regulation of E-cadherin. (12857907)
2003
26
Seroreactivity to epidermodysplasia verruciformis-related human papillomavirus types is associated with nonmelanoma skin cancer. (12750299)
2003
27
Altered p53 expression in benign and malignant skin lesions from renal transplant recipients and immunocompetent patients with skin cancer: correlation with human papillomaviruses? (11552722)
2001
28
Distinctive distribution of human papillomavirus type 16 and type 20 DNA in the tonsillar and the skin carcinomas of a patient with epidermodysplasia verruciformis. (11069510)
2000
29
Prevention of carcinogen-induced mouse skin papilloma by whole fruit aqueous extract of Momordica charantia. (10958332)
2000
30
The promoter of a novel human papillomavirus (HPV77) associated with skin cancer displays UV responsiveness, which is mediated through a consensus p53 binding sequence. (10508168)
1999
31
ComA"l-Netherton syndrome complicated by papillomatous skin lesions containing human papillomaviruses 51 and 52 and plane warts containing human papillomavirus 16. (10354085)
1999
32
Comparative expression of novel vascular endothelial growth factor/vascular permeability factor transcripts in skin, papillomas, and carcinomas of v-Ha-ras Tg.AC transgenic mice and FVB/N mice. (9647747)
1998
33
Human papillomavirus DNA in non-melanoma skin cancers of a renal transplant recipient: detection of a new sequence related to epidermodysplasia verruciformis associated types. (8980287)
1997
34
Skin autografts in epidermodysplasia verruciformis: human papillomavirus-associated cutaneous changes need over 20 years for malignant conversion. (9331078)
1997
35
p53, WAF1/CIP1 and mdm2 expression in skin lesions associated with human papillomavirus and human immunodeficiency virus. (9137486)
1997
36
Suppression of mouse skin papilloma by canthaxanthin and beta-carotene in vivo: possibility of the regression of tumorigenesis by carotenoids without conversion to retinoic acid. (8875557)
1996
37
Epidermodysplasia verruciformis as a model of human papillomavirus-induced genetic cancer of the skin. (7503577)
1995
38
Effect of excess dietary retinoic acid on skin papilloma and carcinoma formation induced by a complete carcinogenesis protocol in female Sencar mice. (8180970)
1994
39
Posttransplant skin cancer: a possible role for p53 gene mutation but not for oncogenic human papillomaviruses. (8176007)
1994
40
Detection of epidermodysplasia verruciformis-like human papillomavirus types in malignant and premalignant skin lesions of renal transplant recipients. (7917987)
1994
41
Mouse skin papilloma formation by chronic dermal application of 7,12-dimethylbenz[a]anthracene is not reduced by diet restriction. (8293538)
1994
42
Alterations in cytokine/antioncogene expression in skin lesions caused by "low-risk" types of human papillomaviruses. (8166933)
1993
43
Effects of dietary retinoic acid on skin papilloma and carcinoma formation in female SENCAR mice. (8453733)
1993
44
Enhanced papilloma formation in response to skin tumor promotion in transgenic mice overexpressing the human ornithine decarboxylase gene. (1520339)
1992
45
Skin hyperkeratosis and papilloma formation in transgenic mice expressing a ras oncogene from a suprabasal keratin promoter. (1696852)
1990
46
A combined carcinogen bioassay utilizing both the lung adenoma and skin papilloma protocols. (3780626)
1986
47
Epidermodysplasia verruciformis. Skin carcinoma containing human papillomavirus type 5 DNA sequences and primary hepatocellular carcinoma associated with chronic hepatitis B virus infection in a patient. (2426900)
1986
48
Dehydroepiandrosterone (DHEA) and 3 beta-methylandrost-5-en-17-one: inhibitors of 7,12-dimethylbenz[a]anthracene (DMBA)-initiated and 12-O-tetradecanoylphorbol-13-acetate (TPA)-promoted skin papilloma formation in mice. (6231135)
1984
49
Inhibition by quercetin of the promoting effect of teleocidin on skin papilloma formation in mice initiated with 7,12-dimethylbenz[a]anthracene. (6428958)
1984
50
Further studies of eel virus (Berlin) isolated from the blood of eels (Anguilla anguilla) with skin papilloma. (981684)
1976

Genetic Variations for Skin Papilloma

Expression for genes affiliated with Skin Papilloma

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Skin Papilloma

Search GEO for disease gene expression data for Skin Papilloma.

Pathways for genes affiliated with Skin Papilloma

Sources:
38NCBI BioSystems Database, 30KEGG, 52QIAGEN
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Compounds for genes affiliated with Skin Papilloma

Sources:
45Novoseek, 11DrugBank, 50PharmGKB, 60Tocris Bioscience, 24HMDB
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Compounds related to Skin Papilloma according to GeneCards/GeneDecks:

(show all 12)
idCompoundScoreTop Affiliating Genes
13,3-diindolylmethane459.9TP53, VEGFA
2temozolomide45 1110.8TP53, VEGFA
3taxane459.8VEGFA, TP53
4triptolide459.8TP53, VEGFA
5bortezomib45 1110.7TP53, VEGFA, CHUK
6geldanamycin45 50 60 1112.7TP53, VEGFA, CHUK
7resveratrol45 60 11 2412.7CHUK, VEGFA, TP53
8egcg459.7TP53, VEGFA, CHUK
9curcumin459.6CHUK, VEGFA, TP53
10arsenite45 2410.6TP53, VEGFA, CHUK
11radicicol45 60 1111.5TP53, VEGFA
125fluorouracil459.4TP53, VEGFA, CHUK

GO Terms for genes affiliated with Skin Papilloma

Sources:
16Gene Ontology
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Biological processes related to Skin Papilloma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1lactationGO:0075959.8VEGFA, CHUK
2DNA strand renaturationGO:0007339.8TP53, SMARCAL1
3mammary gland alveolus developmentGO:0607499.7VEGFA, CHUK
4regulation of transcription from RNA polymerase II promoterGO:0063579.1SMARCAL1, VEGFA, PRKAR1A

Products for genes affiliated with Skin Papilloma

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Sources for Skin Papilloma

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet