MCID: SKN011
MIFTS: 22

Skin Pilomatrix Carcinoma

Categories: Cancer diseases, Skin diseases

Aliases & Classifications for Skin Pilomatrix Carcinoma

MalaCards integrated aliases for Skin Pilomatrix Carcinoma:

Name: Skin Pilomatrix Carcinoma 12 14
Pilomatrix Carcinoma of Skin 12 69
Pilomatricoma, Malignant 12
Malignant Pilomatricoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5376
NCIt 46 C4114
SNOMED-CT 64 24762001 307610008
UMLS 69 C0585475

Summaries for Skin Pilomatrix Carcinoma

MalaCards based summary : Skin Pilomatrix Carcinoma, also known as pilomatrix carcinoma of skin, is related to pilomatrix carcinoma and hair follicle neoplasm. An important gene associated with Skin Pilomatrix Carcinoma is KRT31 (Keratin 31), and among its related pathways/superpathways are DNA Damage Response (only ATM dependent) and Glioblastoma Multiforme. Affiliated tissues include skin.

Related Diseases for Skin Pilomatrix Carcinoma

Diseases related to Skin Pilomatrix Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 pilomatrix carcinoma 11.2
2 hair follicle neoplasm 9.8 CTNNB1 HOXC13
3 arrhythmogenic right ventricular cardiomyopathy 9.6 CTNNB1 LEF1

Symptoms & Phenotypes for Skin Pilomatrix Carcinoma

Drugs & Therapeutics for Skin Pilomatrix Carcinoma

Search Clinical Trials , NIH Clinical Center for Skin Pilomatrix Carcinoma

Genetic Tests for Skin Pilomatrix Carcinoma

Anatomical Context for Skin Pilomatrix Carcinoma

MalaCards organs/tissues related to Skin Pilomatrix Carcinoma:

38
Skin

Publications for Skin Pilomatrix Carcinoma

Articles related to Skin Pilomatrix Carcinoma:

# Title Authors Year
1
Expression patterns of hair and epithelial keratins and transcription factors HOXC13, LEF1, and beta-catenin in a malignant pilomatricoma: a histological and immunohistochemical study. ( 16441405 )
2006

Variations for Skin Pilomatrix Carcinoma

Expression for Skin Pilomatrix Carcinoma

Search GEO for disease gene expression data for Skin Pilomatrix Carcinoma.

Pathways for Skin Pilomatrix Carcinoma

GO Terms for Skin Pilomatrix Carcinoma

Cellular components related to Skin Pilomatrix Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein-DNA complex GO:0032993 8.96 CTNNB1 LEF1
2 beta-catenin-TCF complex GO:1990907 8.62 CTNNB1 LEF1

Biological processes related to Skin Pilomatrix Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transcription by RNA polymerase II GO:0006366 9.65 CTNNB1 HOXC13 LEF1
2 cornification GO:0070268 9.46 KRT31 KRT35
3 canonical Wnt signaling pathway GO:0060070 9.43 CTNNB1 LEF1
4 odontogenesis of dentin-containing tooth GO:0042475 9.4 CTNNB1 LEF1
5 positive regulation of epithelial to mesenchymal transition GO:0010718 9.37 CTNNB1 LEF1
6 beta-catenin-TCF complex assembly GO:1904837 9.32 CTNNB1 LEF1
7 epithelial to mesenchymal transition GO:0001837 9.26 CTNNB1 LEF1
8 Wnt signaling pathway, calcium modulating pathway GO:0007223 9.16 CTNNB1 LEF1
9 branching involved in blood vessel morphogenesis GO:0001569 8.96 CTNNB1 LEF1
10 vasculature development GO:0001944 8.62 CTNNB1 LEF1

Molecular functions related to Skin Pilomatrix Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 chromatin binding GO:0003682 9.13 CTNNB1 HOXC13 LEF1
2 estrogen receptor binding GO:0030331 8.62 CTNNB1 LEF1

Sources for Skin Pilomatrix Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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